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MLS 3-D
HEMATOLOGY
12/11/14
POIKILOCYTES
Name
Acanthocyte
Synonyms
Spur cell
Illustration
Description
Associated Diseases
Abetalipoproteinemi
a
Severe hepatic
disease
Myeloproliferative
disorders
MAHA
Neuroacanthocytosis
Syndromes
Blister cell
Burr cell
Echinocyte
indication of
pulmonary emboli in
sickle cell anemia
A variety of anemias
Bleeding gastric ulcers
Abegail Ibanez
MLS 3-D
HEMATOLOGY
12/11/14
Crenated
erythrocyte
Echinocyte
Elliptocyte
Elliptocyte
Helmet cell
Schizocyte,
keratocyte
Gastric carcinoma
Peptic
Renal insufficiency
Pyruvate kinase defi
ciency
Uremia
Result from osmotic
imbalance
Dse-none
iron deficiency
anemia
myelofibrosis
megaloblastic
anemia
sickle cell anemia
hereditary
elliptocytosis
anemias associated
with malignancy
hemoglobin (Hb) C
disease
Hemolytic
anemias(occasionally)
pernicious anemia
sickle cell trait
thalassemia
Abegail Ibanez
MLS 3-D
HEMATOLOGY
Normal
erythrocyte
Oval macrocyte
Discocyte
Ovalocyte
Ovalocyte
Pyknocyte
Megalocyte
12/11/14
blister cell
formed as a result of the
physical process of
fragmentation
formed in the spleen and
intravascular fibrin clots
Abegail Ibanez
Schistocyte
MLS 3-D
Schizocyte
HEMATOLOGY
Sickle cell
Drepanocyte,
meniscocyte
Spiculated
erythrocyte
Spherocyte
burr cells,
crenated cells,
pyknocytes,
spur cells,
acanthocytes,
and
echinocytes
Spherocyte
12/11/14
fragments of erythrocytes
small and irregularly
shaped.
produced as the result of
the breaking apart of an
erythrocytes
about half the size of a
normal erythrocyte
may have a deeper red
appearance
resemble a crescent
At least one of the ends of
the cell must be pointed
the membrane is smooth
and the cell stains
uniformly throughout
irregularly contracted
erythrocytes
nearly spherical
erythrocytes, in
contradistinction to
normal biconcave disks.
diameter is smaller than
normal
lack the central pale area
or have a smaller, often
eccentric, pale area
(because the cell is
Hemolytic anemias
related to burns or
prosthetic implants
Renal transplant
rejection
Hereditary
spherocytosis
Certain hemolytic
anemias
Severe burns
Abegail Ibanez
MLS 3-D
HEMATOLOGY
12/11/14
Stomatocyte
Target cell
Codocyte
Teardrop
Keratocyte
Dacryocyte
bull's-eye morphology
erythrocytes that are
thinner than normal
(leptocytes)
peripheral rim of
hemoglobin (Hb),
dark, central, Hbcontaining area
Hemoglobinopathies
(e.g., sickle cell
disease)
hypochromic
anemia
Certain thalassemias
Splenectomy
obstructive jaundice
Myelofibrosis with
myeloid metaplasia
(MMM)
Disseminated (diffuse)
intravascular
coagulation (DIC)
Abegail Ibanez
MLS 3-D
HEMATOLOGY
Knizocyte
Leptocyte
12/11/14
spicules,resembling two
horns, result from a
ruptured vacuole
Usually the cell appears
like a half-moon or spindle
resemble a pinched bottle
hemolytic anemias :
hereditary
spherocytosis
hepatic disorders
iron deficiency
anemia
thalassemia
Abegail Ibanez
MLS 3-D
HEMATOLOGY
12/11/14
Abegail Ibanez
MLS 3-D
HEMATOLOGY
12/11/14