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4.2 Solvents
Most solvents are liquid organic chemicals. They are used because of their ability to dissolve other
substances, particularly fat and grease, which are insoluble in water. Many of them evaporate rapidly at
ambient temperatures. They are often flammable and may ignite by heat from smoking, welding or static
electricity. Vapours move with air currents and can ignite even by a distant heat source.
Inhalation is the most common way for solvents to enter the body, but some of them penetrate intact healthy
skin. Once in the blood stream a solvent can be transported to different organs, such as the brain and liver.
Solvents have different effects on humans, depending on their evaporation rate and their solubility in water.
The risks of health effects depend on the period of exposure and the concentration of the solvent in the
inhaled air.
Many solvents have a narcotic effect; they may cause dizziness, headache, reduced comprehension or
tiredness. They may also irritate the eyes and the respiratory tract. Frequent skin contact defats the protective
layer of the skin causing irritation. Some solvents are very hazardous to the liver, kidneys, bone marrow or
nervous system. Benzene, carbon tetrachloride and carbon disulphide belong to the category of solvents
which should be substituted with less dangerous ones.
4.3 Metals
Metals can enter the body in the form of dust and fumes (in grinding or welding) or even through the skin. One
of these is tetraethyl lead, which is used as an anti-knocking agent in petrol. Mercury vapours are often
inhaled, as this liquid metal evaporates readily at room temperatures.
Lead is used in various industries: battery, glass and mining industries, cable manufacturing, foundries and in
printing works. Steel constructions are protected with anti-corrosive paint containing lead, which may be
released during welding operations, for example, on ships.
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4.5 Pesticides
Pesticides are intended to destroy or control pests of all kind. They are used in industry, for example, to
impregnate wood, and in agriculture to control insects, weed, fungi, and rats. These are many different types
of pesticide compounds and they are used also as mixtures.
Some countries apply restrictions in using certain compounds, and the use of some of them is completely
banned because of their serious adverse effects. In Europe, the list of banned pesticides includes compounds
such as inorganic mercury compounds, camphechlor, chlordane, dieldrin, DDT, HCH (lindane), heptachlor,
hexachlorobenzene, and nitrofen.
Insecticides are divided into following broad groups:
Organophosphorous compounds
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Picture
Picture
Picture
Picture 12
9
10
11
assess chemical hazards and set priorities concerning the safety in the organisation;
create emergency plans for the assessed hazards;
organize occupational health care and regular surveys as necessary;
organize contacts with authorities/laboratories to createa monitoring system for chemical hazards,
and to reliably measure and/or estimate occupational exposures to chemicals when needed;
start collecting case studies of accidents and sickness records in the enterprise to create a basis for
priority measures in the control of hazards;
identify chemicals in use;
obtain information of their hazards;
collect this data and make an inventory list of all chemicals used in the factory: create a Register for
Workplace Chemicals;
involve workers in safety organizations, such as the system of Safety Representatives, and Safety
Committees;
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13
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reduce the length of time and/or frequency of exposure of workers to dangerous chemicals;
train workers to know and understand the emergency procedures;
equip and train workers to use personnel protective equipment properly after all that is possible has
been done to eliminate hazards by means of other methods.
5.3 Storage
Planning and maintaining storage areas is very relevant for users of chemicals in order to avoid material
losses, accidents and disasters. Special attention should be paid to incompatible substances, suitable
location of products within the storage area and proper arrangements and climatic conditions. For example,
cylinders should be fixed with chains to upright position and the acids in the area or cupboard meant only for
them. The fumes or splashes should never reach the area where cylinders are kept.
Hazardous substances can leak, cause a fire or give off dangerous fumes and vapours. When two
substances come into contact with one another, they may react violently. The reaction products may be much
more dangerous than the original chemicals.
Written instructions of storage practices should be provided, and chemical safety data sheets of dangerous
substances kept in stock should be available in the storage area.
5.4 Waste
Chemicals react in the same characteristic ways whether they are wastes or are used in a production
process. The hazards are also the same. Where chemicals are used, the enterprise should plan labelling,
collecting and handling of wastes. Some countries have introduced legislation and provide detailed advises
on how to treat dangerous chemical waste. To gain maximum benefit for all, a response is essential, from the
shop-floor, where the chemicals are actually used, up to the management, which should plan the whole, safe
`lifecycle' for every substance. Cooperation with and within authorities is needed to fulfill these tasks.
Many accidents have based on a good belief that everyone is aware of the situation. Discuss in the work
place the ideas arising when asking the following questions:
Picture
Picture 16
15
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If the work cannot be finished today can it be left in a safe state? Are clear instructions available for
the next shift?
How is the communication in your work place? Do those in production know what maintenance is
going to be done, are any closures in some part of the production? Do the maintenance people know
the special demands of the jobs related to the one they are working on?
Is there any organized checking that the jobs are done in the way intended, or for general good house
keeping?
BIBLIOGRAPHY
ARBETARSKYDDSNMNDEN, Kemiska hlsorisker, Gummessons Tryckeri, Falkping, Sweden, 1990
BAKAR CHE MAN A. and GOLD D., Safety and Health in the use of Chemicals at Work: A training manual,
ILO, Geneva, 1993
FAO, Food and Agriculture Organization of the United Nations, International Code of Conduct on the
Distribution and Use of Pesticides, Rome 1990
HALTON D.M., How Workplace Chemicals Enter the Body, CCOHS, Canadian Centre for Occupational
Health and Safety, Hamilton, Ontario, 1985
HSE, Health and Safety Executive, Essentials of Health and Safety at work, HMSO, London, 1990
ILO, International Labour Organisation, Code of Practice: Safety in the Use of Chemicals at Work, Geneva
1993
ILO, International Labour Organisation, Safety and Health in the use of Agrochemicals: A Guide, Geneva,
1991
IPCS, International Programme on Chemical Safety, How to use the IPCS Health and Safety Guides
JOINT INDUSTRIAL SAFETY COUNCIL, Safety-Health and Working Conditions, TIBA Tryck AB, Stockholm,
1987
91/659/EEC Commission Directive of 3 December 1991 adapting to technical progress Annex I to Council
Directive 76/769/EEC on the approximation of the laws, regulations and administrative provisions of the
Member States relating to restrictions on the marketing and use of certain dangerous substances and
preparations (asbestos)
2455/92/EEC Council Regulation of 23 July 1992 concerning the export and import of certain dangerous
chemicals
Sykes R., Vhpassi A. and Ens H., Guidelines on Inspection of Chemical Factories, Especially Major
Accident Hazard Installations, Jakarta, 1990
TUC, Trade Union Congress, Hazards at Work, TUC Guide to health and safety, Macdermott and Chant Ltd.,
London, 1988
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for,
and
right
to,
information
about
the
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Article 1
1. This Convention
chemicals are used.
applies
to
all
branches
of
economic
activity
in
which
Article 2
For the purposes of this Convention:
(a) the term chemicals means chemical elements and compounds and
mixtures thereof, whether natural or synthetic;
(b) the term hazardous chemical includes any chemical which has
been classified as hazardous in accordance with Article 6 or
for which relevant information exists to indicate that the
chemical is hazardous;
(c) the term use of chemicals at work means any work activity
which may expose a worker to a chemical, including:
(i) the production of chemicals;
(ii) the handling of chemicals;
(iii)
the storage of chemicals;
(iv) the transport of chemicals;
(v) the disposal and treatment of waste chemicals;
(vi) the release of chemicals resulting from work activities;
(vii)
the maintenance, repair and cleaning of equipment
and containers for chemicals;
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Article 3
The most representative organisations of employers and workers
concerned shall be consulted on the measures to be taken to give
effect to the provisions of this Convention.
Article 4
In the light of national conditions and practice and in
consultation
with
the
most
representative
organisations
of
employers and workers, each Member shall formulate, implement and
periodically review a coherent policy on safety in the use of
chemicals at work.
Article 5
The competent authority shall have the power, if justified on
safety and health grounds, to prohibit or restrict the use of
certain hazardous chemicals, or to require advance notification and
authorisation before such chemicals are used.
Article 6
CLASSIFICATION SYSTEMS
1. Systems and specific criteria appropriate for the classification
of all chemicals according to the type and degree of their
intrinsic health and physical hazards and for assessing the
relevance of the information required to determine whether a
chemical is hazardous shall be established by the competent
authority, or by a body approved or recognised by the competent
authority, in accordance with national or international standards.
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systems
and
their
application
shall
be
Article 7
LABELLING AND MARKING
1. All chemicals shall be marked so as to indicate their identity.
2. Hazardous chemicals shall in addition be labelled, in a way
easily understandable to the workers, so as to provide essential
information regarding their classification, the hazards they
present and the safety precautions to be observed.
3.
(1)
Requirements
for
marking
or
labelling
chemicals
pursuant to paragraphs 1 and 2 of this Article shall be
established by the competent authority, or by a body approved
or recognised by the competent authority, in accordance with
national or international standards.
(2)
In the case of transport, such requirements shall take
into account the United Nations Recommendations on the
transport of dangerous goods.
Article 8
CHEMICAL SAFETY DATA SHEETS
1. For hazardous chemicals, chemical safety data sheets containing
detailed essential information regarding their identity, supplier
classification,
hazards,
safety
precautions
and
emergency
procedures shall be provided to employers.
2. Criteria for the preparation of chemical safety data sheets
shall be established by the competent authority, or by a body
approved or recognised by the competent authority, in accordance
with national or international standards.
3. The chemical or common name used to identify the chemical on the
chemical safety data sheet shall be the same as that used on the
label.
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Article 9
RESPONSIBILITIES OF SUPPLIERS
1. Suppliers of chemicals, whether manufacturers, importers or
distributors, shall ensure that:
(a) such chemicals have been classified in accordance with
Article 6 on the basis of knowledge of their properties and a
search of available information or assessed in accordance with
paragraph 3 below;
(b) such chemicals are marked so as to indicate their identity
in accordance with Article 7, paragraph 1;
(c) hazardous chemicals they supply are labelled in accordance
with Article 7, paragraph 2;
(d) chemical safety data sheets are prepared for such
hazardous chemicals in accordance with Article 8, paragraph 1,
and provided to employers.
2. Suppliers of hazardous chemicals shall ensure that revised
labels and chemical safety data sheets are prepared and provided to
employers, by a method which accords with national law and
practice, whenever new relevant safety and health information
becomes available.
3. Suppliers of chemicals which have not yet been classified in
accordance with Article 6 shall identify the chemicals they supply
and assess the properties of these chemicals on the basis of a
search of available information in order to determine whether they
are hazardous chemicals.
Article 10
IDENTIFICATION
1. Employers shall ensure that all chemicals used at work are
labelled or marked as required by Article 7 and that chemical
safety data sheets have been provided as required by Article 8 and
are made available to workers and their representatives.
2. Employers receiving chemicals that have not been labelled or
marked as required under Article 7, or for which chemical safety
data sheets have not been provided as required under Article 8
shall obtain the relevant information from the supplier or from
other reasonably available sources, and shall not use the chemicals
until such information is obtained.
3. Employers shall ensure that only chemicals which are classified
in accordance with Article 6 or identified and assessed in
accordance with Article 9, paragraph 3, and labelled or marked in
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that
any
necessary
Article 11
TRANSFER OF CHEMICALS
Employers shall ensure that when chemicals are transferred into
other containers or equipment, the contents are indicated in a
manner which will make known to workers their identity, any hazards
associated with their use and any safety precautions to be
observed.
Article 12
EXPOSURE
Employers shall:
(a) ensure that workers are not exposed to chemicals to an
extent which exceeds exposure limits or other exposure
criteria for the evaluation and control of the working
environment established by the competent authority, or by a
body approved or recognised by the competent authority, in
accordance with national or international standards;
(b) assess the exposure of workers to hazardous chemicals;
(c) monitor and record the exposure of workers to hazardous
chemicals when this is necessary to safeguard their safety and
health or as may be prescribed by the competent authority;
(d) ensure that the records of the monitoring of the working
environment and of the exposure of workers using hazardous
chemicals are kept for a period prescribed by the competent
authority and are accessible to the workers and their
representatives.
Article 13
OPERATIONAL CONTROL
1. Employers shall make an assessment of the risks arising from the
use of chemicals at work, and shall protect workers against such
risks by appropriate means, such as:
(a) the choice of chemicals that eliminate or minimise the
risk;
(b) the choice of technology that eliminates or minimises the
risk;
(c) the use of adequate engineering control measures;
(d) the adoption of working systems and practices that
eliminate or minimise the risk;
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Article 15
INFORMATION AND TRAINING
Employers shall:
(a) inform the workers of the hazards associated with exposure
to chemicals used at the workplace;
(b) instruct the workers how to obtain and use the information
provided on labels and chemical safety data sheets;
(c) use the chemical safety data sheets, along with
information specific to the workplace, as a basis for the
preparation of instructions to workers, which should be
written if appropriate;
(d) train the workers on a continuing basis in the practices
and procedures to be followed for safety in the use of
chemicals at work.
Article 16
CO-OPERATION
Employers, in discharging their responsibilities, shall co-operate
as closely as possible with workers or their representatives with
respect to safety in the use of chemicals at work.
Article 17
1. Workers shall co-operate as closely as possible with their
employers
in
the
discharge
by
the
employers
of
their
responsibilities and comply with all procedures and practices
relating to safety in the use of chemicals at work.
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Article 18
1. Workers shall have the right to remove themselves from danger
resulting from the use of chemicals when they have reasonable
justification to believe there is an imminent and serious risk to
their safety or health, and shall inform their supervisor
immediately.
2. Workers who remove themselves from danger in accordance with the
provisions of the previous paragraph or who exercise any other
rights under this Convention shall be protected against undue
consequences.
3. Workers concerned and their representatives shall have the right
to:
(a) information on the identity of chemicals used at work, the
hazardous properties of such chemicals, precautionary measures
education and training;
(b) the information contained in labels and markings;
(c) chemical safety data sheets;
(d) any other information required to be kept by this
Convention.
4. Where disclosure of the specific identity of an ingredient of a
chemical mixture to a competitor would be liable to cause harm to
the employer's business, the employer may, in providing the
information required under paragraph 3 above, protect that identity
in a manner approved by the competent authority under Article 1
paragraph 2 (b).
Article 19
When in an exporting member State all or some uses of hazardous
chemicals are prohibited for reasons of safety and health at work
this fact and the reasons for it shall be communicated by the
exporting member State to any importing country.
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Article 20
The formal ratifications of this Convention shall be communicated
to the Director-General of the International Labour Office for
registration.
Article 21
1. This Convention shall be binding only upon those Members of the
International Labour Organisation whose ratifications have been
registered with the Director-General.
2. It shall come into force twelve months after the date on which
the ratifications of two Members have been registered with the
Director-General.
3. Thereafter, this Convention shall come into force for any Member
twelve months after the date on which its ratification has been
registered.
Article 22
1. A Member which has ratified this Convention may denounce
after the expiration of ten years from the date on which
Convention first comes into force, by an act communicated to
Director-General
of
the
International
Labour
Office
registration. Such denunciation shall not take effect until
year after the date on which it is registered.
it
the
the
for
one
2. Each Member which has ratified this Convention and which does
not, within the year following the expiration of the period of ten
years mentioned in the preceding paragraph, exercise the right of
denunciation provided for in this Article, will be bound for
another period of ten years and, thereafter, may denounce this
Convention at the expiration of each period of ten years under the
terms provided for in this Article.
Article 23
1. The Director-General of the International Labour Office shall
notify all Members of the International Labour Organisation of the
registration of all ratifications and denunciations communicated to
him by the Members of the Organisation.
2. When notifying the Members of the Organisation of the
registration of the second ratification communicated to him, the
Director-General shall draw the attention of the Members of the
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Organisation to the date upon which the Convention will come into
force.
Article 24
The Director-General of the International Labour Office shall
communicate to the Secretary-General of the United Nations for
registration in accordance with Article 102 of the Charter of the
United Nations full particulars of all ratifications and acts of
denunciation registered by him in accordance with the provisions of
the preceding Articles.
Article 25
At such times as it may consider necessary the Governing Body of
the International Labour Office shall present to the General
Conference a report on the working of this Convention and shall
examine the desirability of placing on the agenda of the Conference
the question of its revision in whole or in part.
Article 26
1. Should the Conference adopt a new Convention revising this
Convention in whole or in part, then, unless the new Convention
otherwise provides:
(a) the ratification by a Member of the new revising
Convention shall ipso jure involve the immediate denunciation
of this Convention, notwithstanding the provisions of Article
22 above, if and when the new revising Convention shall have
come into force;
(b) as from the date when the new revising Convention comes
into force this Convention shall cease to be open to
ratification by the Members.
2. This Convention shall in any case remain in force in its actual
form and content for those Members which have ratified it but have
not ratified the revising Convention.
Article 27
The English and French versions of the text of this Convention are
equally authoritative.
I. GENERAL PROVISIONS
1. The provisions of this Recommendation should be applied in
conjunction with those of the Chemicals Convention, 1990 (hereafter
referred to as "the Convention").
2. The most representative organisations of employers and workers
concerned should be consulted on the measures to be taken to give
effect to the provisions of this Recommendation.
3. The competent authority should specify categories of workers who
for reasons of safety and health are not allowed to use specified
chemicals or are allowed to use them only under conditions
prescribed in accordance with national laws or regulations.
4. The provisions of this Recommendation should also apply to such
self-employed persons as may be specified by national laws or
regulations.
5. The special provisions established by the competent authority to
protect confidential information, under Article 1, paragraph 2(b)
and Article 18, paragraph 4, of the Convention, should:
(a) limit the disclosure of confidential information to those
who have a need related to workers' safety and health;
(b) ensure that those who obtain confidential information
agree to use it only to address safety and health needs and
otherwise to protect its confidentiality;
(c)
provide
that
relevant
confidential
information
be
disclosed immediately in an emergency;
(d) provide for procedures to consider promptly the validity
of the confidentiality claim and of the need for the
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MEDICAL SURVEILLANCE
18.
(1) The employer, or the institution competent under national
law and practice, should be required to arrange, through a
method which accords with national law and practice, such
medical surveillance of workers as is necessary:
(a) for the assessment of the health of workers in relation to
hazards caused by exposure to chemicals;
(b) for the diagnosis of work-related diseases and injuries
caused by exposure to hazardous chemicals.
(2) Where the results of medical tests or investigations
reveal clinical or preclinical effects, measures should be
taken to prevent or reduce exposure of the workers concerned,
and to prevent further deterioration of their health.
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IV. CO-OPERATION
20. Employers, workers and their representatives should co-operate
as closely as possible in the application of measures prescribed
pursuant to this Recommendation.
21. Workers should be required to:
(a) take care as far as possible of their own safety and
health and of that of other persons who may be affected by
their acts or omissions at work in accordance with their
training and with instructions given by their employer;
(b) use properly all devices provided for their protection or
the protection of others;
(c) report forthwith to their supervisor any situation which
they believe could present a risk, and which they cannot
properly deal with themselves.
22. Publicity material concerning hazardous chemicals intended for
use at work should call attention to their hazards and the
necessity to take precautions.
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V. RIGHTS OF WORKERS
24.
(1) Workers and their representatives should have the right
to:
(a) obtain chemical safety data sheets and other information
from the employer so as to enable them to take adequate
precautions, in co-operation with their employer, to protect
workers against risks from the use of hazardous chemicals at
work;
(b) request and participate in an investigation by the
employer or the competent authority of possible risks
resulting from the use of chemicals at work.
(2) Where the information requested is confidential in
accordance with Article 1, paragraph 2 (b), and Article 18,
paragraph 4, of the Convention, employers may require the
workers or workers' representatives to limit its use to the
evaluation and control of possible risks arising from the use
of chemicals at work, and to take reasonable steps to ensure
that
this
information
is
not
disclosed
to
potential
competitors.
(3) Having regard to the Tripartite Declaration of Principles
concerning
Multinational
Enterprises
and
Social
Policy
multinational enterprises should make available, upon request,
to workers concerned workers' representatives, the competent
authority and employers' and workers' organisations in all
countries in which they operate, information on the standards
and procedures related to the use of hazardous chemicals
relevant to their local operations which they observe in other
countries.
25.
(1) Workers should have the right:
(a) to bring to the attention of their representatives, the
employer or the competent authority, potential hazards arising
from the use of chemicals at work;
(b) to remove themselves from danger resulting from the use of
chemicals when they have reasonable justification to believe
there is an imminent and serious risk to their safety or
health, and should inform their supervisor immediately;
(c) in the case of a health condition, such as chemical
sensitisation, placing them at increased risk of harm from a
hazardous chemical, to alternative work not involving that
chemical, if such work is available and if the workers
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This information is obtained from laboratory tests with cells, bacteria, animals and from accidents involving
the substance.
Large amounts of toxicological information are collected into data bases and data banks.
2. Exposure
To have an adverse effect a substance must be able to enter the system. The exposure depends of the
amount of substance and the period during which it affects the target, e.g. humans, animals or bacteria.
2.1 Routes
The major routes through which the toxic substances may enter the body, under normal working condition,
are: inhalation, through the skin and ingestion.
For many substances the greatest effects and the most rapid responses occurs when the substance is
inserted directly into the blood circulation. In toxicological animal experiments the routes of exposure may be:
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Local/systemic toxicity
There are two main ways in which chemicals may exert their effects. Local effects occur at the area of the
body which has been in contact with the chemical. Examples are injuries from acids or lung injuries from
inhaled reactive gases. Systemic effects occur after the chemical has been absorbed and distributed from the
entry point to other parts of the body. Most substances produce systemic effects, but some substances may
cause both types of effects. An example is tetraethyl lead, which is a gasoline additive and produces skin
effects at the contact site. It is absorbed and transported into the body causing typical effects on the central
nervous system and on other organs.
Target organs
The degree of the toxic effect is not the same in all organs. Usually there are one or two organs which show
the major toxic effect. These are referred as target organs of toxicity of the particular substance. The central
nervous system is the target organ of toxicity most frequently involved in systemic effects. The blood
circulation system, liver, kidneys, lungs and skin follow in frequency of systemic effects. Muscle and bones are
the target organs for a few substances. The male and female reproduction systems are vulnerable to many
substances.
Skin is the largest organ in the human body, 1.5-2 m 2 in area. It provides a protective cover to the
body but can fail if the load is overwhelming. A number of substances can penetrate healthy intact
Page 31 of 236
Allergic reactions
An allergic reaction, or sensitization as it is also called, may appear after repeated contact to a substance.
Once the sensitization has bee produced, even very low doses can provoke a reaction. The different allergies
are numerous, varying from minor skin irritation to very severe or even fatal reactions.
The pattern of sensitization varies according to the species. In humans, the skin and the eyes are the most
common areas of allergic response, whereas, for example, in the guinea pigs reactions are more common in
the respiratory system.
Interactions
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BIBLIOGRAPHY
ARBETSMILJ (Working Environment/ The Work Environment Association), Your body at work, 2nd Ed.,
Stockholm 1987
CLAYTON G.D. and CLAYTON F.E., ed., Patty's Industrial Hygiene and Toxicology, 3rd Revised Ed., John
Wiley & Sons Inc., USA 1978
Page 33 of 236
Page 34 of 236
The United Nations Recommendations on the Transport of Dangerous Goods is widely recognized
and used among the UN member states.
An example of a system that has been designed for use in several countries is the classification and
labelling system of the European Communities (EC).
Several functioning national systems, such as those of Canada and USA, may also be used as
models for national systems.
This guide could be used as training material or at places of work when individual labels are checked or
prepared using the data on chemical substances listed in Annex 4. It may also serve as reference material, or
as a manual, providing basic safety information on these substances.
This guide describes the labelling system used in the countries of the European Union (EU) as an example
and the United Nations Recommendations on the Transport of Dangerous Goods is also briefly presented.
This document consists of:
Page 35 of 236
Page 37 of 236
F+
T+
Explanation
explosive
This symbol with the word 'explosive' denotes a substance which may explode under the effect of a
flame or if subjected to shocks or friction.
oxidizing
The symbol with the word 'oxidizing' refers to a substance which releases a lot of heat while it
reacts with other substances, particularly flammable substances.
highly flammable
This symbol with the words 'highly flammable' denotes a substance which may become hot and
finally catch fire in contact with air at ambient temperature or is a solid and may readily catch fire
after brief contact with the source of ignition and which continues to burn/to be consumed by
chemical reaction after removal of the source of ignition. If it is gas it may burn in air at normal
pressure. If it is a liquid it would catch fire with slight warming and exposure to a flame. In contact
with water or damp air the substance may release highly flammable gases in dangerous quantities.
extremely flammable
The same flammable symbol as above with words 'extremely flammable' denotes e.g. a liquid which
would boil at body temperature and would catch fire if vapours are exposed to a flame.
toxic
The symbol with skull and crossed bones with the word 'toxic' denotes a highly hazardous
substance.
very toxic
The same symbol as above with the words 'very toxic' is used to label a substance, which, if inhaled
or ingested or, if it penetrates the skin, may involve extremely serious immediate or long-term health
Page 38 of 236
Xn
Xi
less than 0.1% by weight for substances classified as very toxic T+, or toxic T
less than 1% for substances classified as harmful Xn, corrosive C, irritant Xi,
Information such as "non-toxic", "not harmful" should not be used in the labels.
The pictorial symbol indicating danger is drawn in black and the background colour should be orange.
The dimensions of the label:
Capacity of the package
Minimum dimensions in
millimeters
52x74
74x105
Each danger symbol must cover at least 1/10 of the surface area of the label. The minimum size of the
danger symbol shall not be less than 10mm x 10mm.
Example 1. Classification of a substance
1,1,1-Trichloroethane, used as solvent
Classified as harmful Xn and dangerous to the environment N, with following
R-phrases and S-phrases
R 20
Harmful by inhalation.
R 59
Dangerous for the ozone layer.
S2
Keep out of the reach of children.
S 24/25 Avoid contact with skin and eyes.
S 59
Refer to manufacturer/supplier for information on recovery/recycling.
Page 39 of 236
Symbol
Risk phrases
Safety phrases
R45
S53-45
Xn,N
Xn
T,N
R20-59
R10-20/21-38
R45-10-20/21-59
S24/25-59-61
S25
S53-45-59-61
Flammable.
Harmful by inhalation.
Harmful by inhalation and in contact with skin.
Irritating to skin.
Dangerous for the ozone layer.
Avoid contact with skin and eyes.
Avoid contact with eyes.
In case of accident or if you feel unwell, seek medical advice immediately (show the
label where possible)
Avoid exposure-obtain special instructions before use.
Refer to manufacturer/supplier for information on recovery/recycling.
Avoid release to the environment. Refer to special instructions/Safety Data Sheets.
Substance
TOLUENE
CAS number
108-88-3
Symbol
F, Xn
Risk phrase
R11-20
Safety phrase
(2-)16-25-29-33
Page 40 of 236
Page 41 of 236
radioactive
infectious
miscellaneous***
+
+
+
n
n
n
n
n
n
n
n
n
LEGEND:
+ : defined category
n : defined under other legislation or code
- : not defined
* : includes oral, dermal and inhalation toxicity
** : includes reproductive and developmental toxicity
*** : specific to UN RTDG; included in national transport legislation
ILO
none defined
UN RTDG
size of labels
varies with
transport mode.
EC
USA
Minimum label
none defined
dimensions are
defined for
different package
capacities;
contrasted danger
symbols and
background (black
on yellow
background);
language must be
that of the country
where the product
is put on market.
CANADA
1. Supplier
label:must appear
on all controlled
products received at
work-places;
required
information must be
set aside from sales
information;
surrounded by
WHMIS ; must be
printed in
contrasting colours;
must have all texts
in English and
French.
2. Workplace
label:must appear
on all products
produced in a
workplace or
transferred to other
containers by the
employer; may
appear in placard
form on products
received in bulk.
DATA ELEMENTS 1. Trade name
not mandated. 1. Chemical
1. Chemical
1. Supplier label:
2. Chemical
The UN RTDG identity
identity
-product identifier
identity
label defines
2. Hazard symbol 2. Supplier
-supplier
3. Supplier
hazards by the and indication of identification
identification
identification.
use of symbols, danger
3. Appropriate -reference to
4. Hazard symbols colours and
3. Risk phrases
hazard warnings existing CSDS
5. Risk phrases
danger warning 4. Safety phrases
-hazard symbols;
6. Safety phrases words for
5. Supplier
Employer must and for containers
7. Batch
specific hazards identification (full ensure that
over 100 ml:
identification
(explosive,
address and tel.
labels and other -risk and safety
8. Reference to
radioactive,
No.)
forms of
phrases
existing CSDS
corrosive, etc.). 6. EEC number if warning are in -first aid measures
9. Hazard
allocated
English and may 2. Workplace
classification
7. the wording
Page 42 of 236
BIBLIOGRAPHY
CLAYTON G.D. and CLAYTON F.E., ed., Patty's Industrial Hygiene and Toxicology, 3rd Revised Ed., John
Wiley & Sons Inc., USA 1978
67/548/EEC Council Directive of 27 June 1967 on the approximation of laws, regulations and administrative
provisions relating to the classification, packing and labelling of dangerous substances
This directive has been amended seven times and has eighteen adaptations to technical progress.
91/325/EEC Commission Directive of 1 March 1991 adapting to technical progress of the laws, regulations
and administrative provisions relating to the classification, packing and labelling of dangerous substances
92/32/EEC Council Directive of 30 April 1992 amending for the seventh time Directive 67/548/EEC on
approximation of the laws, regulations and administrative provisions relating to the classification, packing and
labelling of dangerous substances
Page 43 of 236
Page 44 of 236
Page 45 of 236
Explosive
Oxidizing
F+
Highly
flammable
Extremely
flammable
T+
Toxic
Very toxic
Page 46 of 236
Xn
Xi
Harmful
Irritant
Corrosive
Dangerous for
environment
Page 47 of 236
ANNEX 2.
Risk Phrases Used in the Countries of EU
(Phrases in parenthesis) are no longer in use.
Nature of Special Risks Attributed to Dangerous Substances and Preparations
R1
R2
R3
R4
R5
R6
R7
R8
R9
R10
R11
R12
(R13
R14
R15
R16
R17
R18
R19
R20
R21
R22
R23
R24
R25
R26
R27
R28
R29
R30
R31
R32
R33
R34
R35
R36
R37
R38
R39
R40
R41
Page 48 of 236
Combination of R-Phrases
R14/15
Reacts violently with water liberating highly flammable gases.
R15/29
Contact with water liberates toxic, highly flammable gas.
R20/21
Harmful by inhalation and in contact with skin.
R20/22
Harmful by inhalation and if swallowed.
R20/21/22
Harmful by inhalation, in contact with skin and if swallowed.
R21/22
Harmful in contact with skin and if swallowed.
R23/24
Toxic by inhalation and in contact with skin.
R23/25
Toxic by inhalation and if swallowed.
R23/24/25
Toxic by inhalation, in contact with skin and if swallowed.
R24/25
Toxic in contact with skin and if swallowed.
R26/27
Very toxic by inhalation and in contact with skin.
R26/28
Very toxic by inhalation and if swallowed.
R26/27/28
Very toxic by inhalation, in contact with skin and if swallowed.
R27/28
Very toxic in contact with skin and if swallowed.
R36/37
Irritating to eyes and respiratory system.
R36/38
Irritating to eyes and skin.
R36/37/38
Irritating to eyes, respiratory system and skin.
R37/38
Irritating to respiratory system and skin.
R39/23
Toxic: danger of very serious irreversible effects through inhalation.
R39/24
Toxic: danger of very serious irreversible effects in contact with skin.
R39/25
Toxic: danger of very serious irreversible effects if swallowed.
R39/23/24
Toxic: danger of very serious irreversible effects through inhalation and in contact with
skin.
R39/23/25
Toxic: danger of very serious irreversible effects through inhalation and if swallowed.
R39/24/25
Toxic: danger of very serious irreversible effects in contact with skin and if swallowed.
R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin
and if swallowed.
Page 49 of 236
R39/26
R39/27
R39/28
R39/26/27
R39/26/28
R39/27/28
R39/26/27/28
R40/20
R40/21
R40/22
R40/20/21
R40/20/22
R40/21/22
R40/20/21/22
R42/43
R48/20
R48/21
R48/22
R48/20/21
R48/20/22
R48/21/22
R48/20/21/22
R48/23
R48/24
R48/25
R48/23/24
R48/23/25
R48/24/25
R48/23/24/25
R50/53
R51/53
R52/53
Page 50 of 236
ANNEX 3
Safety Phrases Concerning Dangerous Chemical Substances and Preparations used
in the Countries of EU
(Phrases in parenthesis) are no longer in use.
S1
S2
S3
S4
S5
S6
S7
S8
S9
S12
S13
S14
S15
S16
S17
S18
S20
S21
S22
S23
S24
S25
S26
S27
S28
S29
S30
S33
(S34
S35
S36
S37
S38
S39
S40
S41
S42
S43
(S44
S45
Page 51 of 236
S46
S47
S48
S49
S50
S51
S52
S53
(S54
(S55
S56
S57
(S58
S59
S60
S61
S62
Combination of S-Phrases
S1/2
Keep locked up and out of reach of children.
S3/7
Keep container tightly closed in a cool place.
(S3/9
Keep in a cool, well-ventilated place.)
(S3/7/9
Keep container tightly closed in a cool, well-ventilated place.)
S3/9/14
Keep in a cool, well-ventilated place away from ... (incompatible materials to be indicated by the
manufacturer).
S3/9/49
Keep only in the original container in a cool, well-ventilated place.
S3/9/14/49 Keep only in the original container in a cool, well-ventilated place away from ... (incompatible
materials to be indicated by the manufacturer).
S3/14
Keep in a cool place away from ... (incompatible materials to be indicated by the manufacturer).
S7/8
Keep container tightly closed and dry.
S7/9
Keep container tightly closed and in a well-ventilated place.
S20/21
When using do not eat, drink or smoke.
S24/25
Avoid contact with skin and eyes.
S36/37
Wear suitable protective clothing and gloves.
S36/39
Wear suitable protective clothing and eye/face protection.
S37/39
Wear suitable gloves and eye/face protection.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S47/49
Keep only in the original container at temperature not exceeding ...C (to be specified by the
manufacturer).
S3/7
Keep container tightly closed in a cool place.
S7/47
Keep container tightly closed and at a temperature not exceeding ...0C (to be specified by the
manufacturer).
S29/56
Do not empty into drains, dispose of this material and its container at hazardous or special
waste collection point.
Page 52 of 236
ANNEX 4.
List of Substances with Risk and Safety Phrases Used in the Countries of EU
Note A
Note B
Where a substance is listed under a generic name (e.g. `...compounds' or `...salts') the
correct chemical name should be stated on the label. For example for BeCl2: Beryllium
chloride
Some substances (acids, bases, etc.) are placed on the market in aqueous solutions at
various concentrations and therefore require different labelling since hazards vary at different
concentrations.
The entries with Note B have a general designation of the type `...% Nitric acid'. The
actual concentration of the solution is stated on the label: `45% Nitric acid.
Note C
Note D
Note E
Note F
Note G
Page No.
Percentages always refer to weight ratio, unless otherwise stated. Additional data
(e.g. specific gravity, Baum values) or descriptions (e.g. glacial, fuming) are
permitted.
Some organic substances may be in a specific isomeric form or as a mixture of isomers with
a general designation. In this case the label states clearly whether the substance is a specific
isomer or a mixture of isomers. For example `Xylene' is specified: `o-Xylene' or `Xylene,
mixture of isomers'.
Some substances which polymerize readily or decompose spontaneously are normally
placed on the market in a stabilized form. However, such substances are sometimes placed
on the market in a non-stabilized form. This must be stated on the label with the name of the
substance:
`Methacrylic acid (non-stabilized)'.
Substances with specific effects on human health (classified as carcinogenic, mutagenic
and/or toxic to reproduction) if they are also classified as `Very toxic (T+)', `Toxic (T)' or
`Harmful (Xn)'. The word also shall precede the risk phrases R20, R21, R22, R23, R24, R25,
R26, R27, R28 when in a combination, for example:
R45-23 May cause cancer. Also toxic by inhalation.
R46-27/28 May cause heritable genetic damage. Also very toxic in contact with skin
and if swallowed.
The substance may contain a stabilizer. If the stabilizer changes the hazardous properties of
the substance as listed, a label must be compiled in accordance with rules for the resulting
hazardous preparations.
The substance may be marketed in an explosive form in which case it must be assessed
using the appropriate test methods and the label should reflect its explosive property.
Page 53 of 236
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
ACEPHATE
(2)-36
ACETAL
(2-)9-16-33
ACETALDEHYDE
(2-)16-33-36/37
ACETAMIDE
(2-)36/37
ACETIC ACID, conc.>90%
(1/2-)23-26-45 Note B
ACETIC ACID, conc. 25%-90%
(1/2-)23-26-45 Note B
ACETIC ANHYDRIDE
(1/2-)26-45
ACETONE
(2-)9-16-23-33
ACETONE CYANOHYDRIN
(1/2-)7/9-27-45-61
ACETONITRILE
(1/2-)16-27-45
ACETOPHENONE
(2-)26
ACETYLACETONE
(2-)21-23-24/25
ACETYL CHLORIDE
(1/2-)9-16-26-45
ACETYLENE
(2-)9-16-33
3-ACETYL-6-METHYL-2H-PYRAN-2,4(3H)-DIONE
(2)
ACLONIFEN
60-61
ACONITINE
(1/2-)24-45
ACONITINE, SALTS
(1/2-)24-45 Note A
ACROLEIN
(1/2-)3/9/14-26-36/37/39-38-45
ACRYLALDEHYDE
(1/2-)3/9/14-26-36/37/39-38-45
ACRYLAMIDE
48/23/24/25 53-45 Note D, E
ACRYLATES, with the exception of those
(2-)26-28
specified elsewhere in this Annex, conc.10%
ACRYLIC ACID
(1/2-)26-36-45 Note D
ACRYLONITRILE
23/24/25-38
53-45 Note D, E
30560-19-1
Xn
22
105-57-7
F,Xi
11-36/38
75-07-0
F+,Xn
12-36/37-40
60-35-5
Xn
40
64-19-7
10-35
34
108-24-7
10-34
67-64-1
11
75-86-5
T+,N
26/27/28-50
75-05-8
F,T
11-23/24/25
98-86-2
Xn
22-36
123-54-3
Xn
10-22
75-36-5
F,C
11-14-34
74-86-2
F+
5-6-12
520-45-6
Xn
22
74070-46-5
50/53
302-27-2
T+
26/28
T+
26/28
107-02-8
F,T+
11-25-26-34
107-02-8
F,T+
11-25-26-34
79-06-1
45-46-24/25-
Xi
36/37/38
79-10-7
10-34
107-13-1
F,T
45-11-
Page 54 of 236
ADIPIC ACID
(2)
ADZN
(2-)39-41-47
ALACHLOR
(2-)36/37/39
ALDICARB
(1/2-)22-36/37-45
ALDRIN
48/24/25-50/53 (1/2-)22-36/37-45-60-61
ALLETHRIN
(2-)36
ALLIDOCHLOR
(2-)26-28-36/37/39
ALLYL ALCOHOL
36/37/38-50 (1/2-)36/37/39-38-45-61
ALLYLAMINE
51/53
(1/2-)9-16-24/25-45-61
5-ALLYL-1,3-BENZODIOXOLE
53-45 Note E
ALLYL CHLORIDE
(1/2-)16-29-33-45-61 Note D
ALLYL 2,3-EPOXYPROPYL ETHER
(2-)24/25
ALLYL GLYCIDYL ETHER
(2-)24/25
ALLYL IODIDE
(1/2-)7-26-45
ALUMINIUM, ALKYLS
(1/2-)16-43-45 Note A
ALUMINIUM CHLORIDE, anhydrous
(1/2-)7/8-28-45
ALUMINIUM LITHIUM HYDRIDE
(2-)7/8-24/25-43
ALUMINIUM PHOSPHIDE
(1/2-)3/9/14-30-36/37-45
ALUMINIUM POWDER, PYROPHORIC
(2-)7/8-43
ALUMINIUM POWDER, STABILIZED
(2-)7/8-43
ALUMINIUM-TRI-ISOPROPOXIDE
(2-)8-16
AMETRYN
(2-)36
AMIDITHION
(2-)24-36
AMINES, POLYETHYLENEPOLY50/53
(1/2-)26-36/37/39-45-60-61
4-AMINOAZOBENZENE
53-45
o-AMINOAZOTOLUENE
53-45
3-AMINOBENZENE SULPHONIC ACID
(2-)25-28
4-AMINOBENZENE SULPHONIC ACID
(2-)24-37
4-AMINOBIPHENYL
53-45 Note E
4-AMINOBIPHENYL, SALTS
124-04-9
78-67-1
E,Xn
2-11-20/22
15972-60-8
Xn
22-40-43
116-06-3
T+
27/28
309-00-2
T,N
24/25-40-
584-79-2
Xn
22
93-71-0
Xn
21/22-36/38
107-18-6
T,N
10-23/24/25-
107-11-9
F,T,N
11-23/24/25-
94-59-7
45-22-40
107-05-1
F,T+,N
11-26-50
106-92-3
Xn
20-43
106-92-3
Xn
20-43
556-56-9
10-34
F,C
14-17-34
7446-70-0
34
16853-85-3
15
20859-73-8
F,T+
15/29-28-32
7429-90-5
15-17
10-15
555-31-7
11
834-12-8
Xn
22
919-76-6
Xn
22
68131-73-7
C,N
21/22-34-43-
60-09-3
45
97-56-3
45-43
121-47-1
Xn
20/21/22
121-57-3
Xi
36/38-43
92-67-1
45-22
45-22
Page 55 of 236
109-73-9
F,C
11-20/21/22-35
13952-84-6
F,C,N
11-20/22-35-50
2032-59-9
24/25
1698-60-8
Xi
43
93-05-0
25-34
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
3-AMINO-N,N'-DIMETHYLANILINE
(1/2-)28-45 Note C
4-AMINO-N,N-DIMETHYLANILINE
(1/2-)28-45 Note C
4-AMINO-2',3-DIMETHYLAZOBENZENE
53-45
2-AMINO-4,6-DINITROPHENOL
52/53
(2-)35-61
2-AMINOETHANOL
(2)
2-AMINOETHYLDIMETHYLAMINE
(1/2-)16-23-26-28-36-45
4-AMINO-3-FLUOROPHENOL
53-45-61 Note E
2-AMINO-2-METHYLPROPANOL
(2)
3-AMINOMETHYL-3,5,5-TRIMETHYLCYCLOHEXYLAMINE
52/53
(1/2-)26-36/37/39-45-61
2-AMINOPHENOL
(2-)28-36/37
5-AMINO-PHENYL-1,2,4-TRIAZOL-1-YL-N,N,N',N'(1/2-)22-28-36/37-45
TETRAMETHYL PHOSPHONIC DIAMIDE
2-AMINOPROPANE
(2-)16-26-29
1-AMINOPROPAN-2-OL
(1/2-)23-26-36-45
3-AMINOPROPYLDIETHYLAMINE
(1/2-)26-36/37/39-45
3-AMINOPROPYLDIMETHYLAMINE
(1/2-)26-36/37/39-45
3-AMINOPROPYLTRIETHOXYSILANE
(1/2-)26-36/37/39-45
2-AMINOTOLUENE
53-45-61 Note E
AMITRAZ
(2-)22
AMITROLE
(2-)36-37-61
AMMONIA, anhydrous
2836-04-6
23/24/25
99-98-9
23/24/25
97-56-3
45-43
96-91-3
E,Xn
1-20/21/22-
141-43-5
Xn
20-36/37/38
108-00-9
F,C
11-21/22-35
399-95-1
T,N
45-22-43-51/53
124-68-5
Xi
36/38
2855-13-2
21/22-34-43-
95-55-6
Xn
20/22-40
1031-47-6
T+
27/28
75-31-0
F+,Xi
12-36/37/38
78-96-6
34
104-78-9
10-21/22-34-43
109-55-7
10-22-34-43
919-30-2
22-34
95-53-4
T,N
45-23/25-36-50
33089-61-1
Xn
22
61-82-5
Xn,N
40-48/22-51/53
7664-41-7
T,N
10-23-34-50
Page 56 of 236
1336-21-6
C,N
34-50
1336-21-6
Xi
36/37/38
1341-49-7
T,C
25-34
2844-92-0
E,T+,N
1-26/27/28-33-
12125-02-9
Xn
22-36
7789-09-5
E,T+,N
49-46-1-8-2137/38-41-43-
12125-01-8
23/24/25
16919-19-0
23/24/25
1341-49-7
T,C
25-34
7790-98-9
9-44
9080-17-5
31-34
628-63-7
10
30899-19-5
Xn
10-20
9000-90-2
Xn
42
Xn
42
638-49-3
10
624-54-4
10
101-05-3
Xi
36/38
62-53-3
T,N
20/21/22-40-
T,N
48/23/24/25-50
20/21/22-40-
90-04-0
T+,N
48/23/24/25-50
45-26/27/28-
104-94-9
T+,N
26/27/28-33-50
Xn
20/22
7647-18-9
34-37
10025-91-9
34-37
ANILINE, SALTS
(1/2-)28-36/37-45-61 Note A
o-ANISIDINE
33-51/53
53-45-61 Note E
p-ANISIDINE
(1/2-)28-36/37-45-61
ANTIMONY COMPOUNDS except TETROXIDE and
(2-)22* Note A
PENTOXIDE, TRISULPHIDE, PENTASULPHIDE and
those specified elsewhere in this Annex
*If appropriate
ANTIMONY PENTACHLORIDE
(1/2-)26-45
ANTIMONY TRICHLORIDE
(1/2-)26-45
Page 57 of 236
ANTIMONY TRIFLUORIDE
7783-56-4
(1/2-)7-26-45
ANTIMONY TRIOXIDE
1309-64-4
(2-)22-36/37
ANTU
86-88-4
(1/2-)25-36/37-45
ARSENIC
7440-38-2
(1/2-)20/21-28-45
ARSENIC ACID and its SALTS
53-45 Note A, E
ARSENIC COMPOUNDS, conc.0.2%, with the
(1/2-)20/21-28-45 Note A
exception of those specified elsewhere in this Annex
ARSENIC OXIDE
1303-28-2
53-45 Note E
ARSENIC PENTOXIDE
1303-28-2
53-45 Note E
ARSENIC TRIOXIDE
1327-53-3
53-45 Note E
ARSINE
7784-42-1
50/53
(1/2-)9-16-28-33-36/37-45-60-61
Page No.
3
18/11/96
Substance
Safety phrases
ASBESTOS
53-45 Note E
ATRAZINE
(2-)36/37-46
ATROPINE
(1/2-)25-45
ATROPINE, SALTS
(1/2-)25-45 Note A
AURAMINE
(2-)36/37-61
AURAMINE, SALTS
(2-)36/37-61 Note A
AZACONAZOLE
(2-)24
AZINPHOS-ETHYL
(1/2-)28-36/37-45
AZINPHOS-METHYL
(1/2-)28-36/37-45
AZIRIDINE
26/27/28-3453-45-61 Note D, E
AZOBENZENE
(2-)28
AZOTHOATE
(2-)13
AZOXYBENZENE
(2-)28
BARBAN
(2-)24-36/37
BARIUM CARBONATE
40
T+
28-40
23/25
45-23/25
23/25
45-23/25
45-23/25
T+
45-28-34
F+,T+,N
12-26-48/20-
Symbol
Risk-phrases
45-48/23
1912-24-9
Xn
20/22-36-40-43
51-55-8
T+
26/28
T+
26/28
Xn,N
22-36-40-51/53
Xn,N
22-36-40-51/53
60207-31-0
Xn
22-44
2642-71-9
T+
24-28
86-50-0
T+
24-28
151-56-4
F,T+,N
45-46-11-
103-33-3
Xn
51/53
20/22
5834-96-8
Xn
20/22
495-48-7
Xn
20/22
101-27-9
Xn
22-43
513-77-9
Xn
22
CAS number
492-80-8
Page 58 of 236
Page 59 of 236
BENZO[d,e,f]CHRYSENE
53-45
BENZO[b]FLUORANTHENE
53-45
BENZO[j]FLUORANTHENE
53-45
BENZO[k]FLUORANTHENE
53-45
BENZOGUANAMINE
(2)
BENZONITRILE
(2-)23
BENZOPHENONE-3,3',4,4'-TETRACARBOXYLIC
(2-)25
DIANHYDRIDE
BENZO[a]PYRENE
53-45
p-BENZOQUINONE
(1/2-)26-28-45
p-BENZOQUINONE 1-BENZOYLHYDRAZONE 4-OXIME
(1/2-)36/37-45
BENZOTHIAZOLE-2-THIOL
(2-)24-37-60-61
1-(2-BENZOTHIAZOLYL)-3-METHYLUREA
(2-)24/25
(BENZOTHIAZOL-2-YLTHIO)SUCCINIC ACID
(2-)24-37
Page No.
4
18/11/96
50-32-8
Substance
Safety phrases
205-99-2
45
205-82-3
45
207-08-9
45
91-76-9
Xn
22
100-47-0
Xn
21/22
2421-28-5
Xi
36/37
50-32-8
45-46-60-61
106-51-4
23/25-36/37/38
495-73-8
21-25
149-30-4
Xi,N
43-50/53
1929-88-0
Xn
22
95154-01-1
Xi
43
CAS number
Symbol
Risk-phrases
I-3-(3-(2H-BENZOTRIAZOL-2-YL)-5-tertXn,N
43-48/22-51/53
(2-)36/37-61
BUTYL-4-HYDROXYPHENYL)PROPIONYLomega-HYDROXYPOLY(OXYETHYLENE) and
I-3-(3-(2H-BENZOTRIAZOL-2-YL)-5-tert-BUTYL-4-HYDROXYPHENYL)PROPIONYLomega-3(3-(2H-BENZOTRIAZOL-2-YL)-5-tert-BUTYL-4-HYDROXYPHENYL)PROPIONYLHYDROXYPOLY(OXYETHYLENE)
BENZOTRICHLORIDE
98-07-7
T
45-22-2337/38-41
53-45 Note E
BENZOTRIFLUORIDE
98-08-8
F,N
11-51/53
(2-)16-23-61
BENZOYL CHLORIDE
98-88-4
C
34
(1/2-)26-45
BENZOYL PEROXIDE
94-36-0
E,Xi
2-7-36-43
(2-)3/7-14-36/37/39
BENZOYLPROP-ETHYL
33878-50-1 Xn
22
(2-)24
BENZTHIAZURON
1929-88-0
Xn
22
(2-)24/25
BENZYL ALCOHOL
100-51-6
Xn
20/22
(2-)26
BENZYLAMINE
100-46-9
C
21/22-34
(1/2-)26-36/37/39-45
BENZYL BENZOATE
120-51-4
Xn
22
(2-)25
Page 60 of 236
BENZYL BROMIDE
(2-)39
BENZYL CHLORIDE
40-41
(1/2-)36/37-38-45
BENZYL CHLOROFORMATE
(1/2-)26-45
S-BENZYL DIISOPROPYL PHOSPHOROTHIOATE
(2)
BENZYLDIMETHYLAMINE
34-52/53
(1/2-)26-36-45-61
S-BENZYL N,N-DIPROPYLTHIOCARBAMATE
(2-)37-61
(N-BENZYL-N-ETHYL)AMINO-3'(2-)26-39-61
HYDROXYACETOPHENONE HYDROCHLORIDE
BENZYL-2-HYDROXYDECYLDIAMMONIUM BENZOATE
(1/2-)26-28-36/37/39-45-60-61
BENZYLIDENE CHLORIDE
40-41
(1/2-)36/37-38-45
BENZYLTRIBUTYLAMMONIUM 4-HYDROXYNAPHTHALENE(2-)22-61
1-SULPHONATE
BENZYL VIOLET 4B
(2-)36/37
BERYLLIUM
36/37/38-
100-39-0
100-44-7
22-23-37/38-
501-53-1
34-37
26087-47-8
Xn
22
103-83-3
10-20/21/22-
52888-80-9
Xn,N
22-48/22-51/53
55845-90-4
Xi,N
41-51/53
113694-52-3 C,N
22-34-50/53
98-87-3
22-23-37/38-
102561-46-6 Xn,N
20-51/53
1694-09-3
Xn
40
7440-41-7
T+
49-25-2643-48/23
53-45, Note E
BERYLLIUM COMPOUNDS
36/37/3853-45 Note A, E
BHC
(1/2-)22-36/37-45-60-61 Note C
BINAPACRYL
53-45 Note E
BIOALLETHRIN
(2-)24
S-BIOALLETHRIN
(2-)36/37-60-61
BIPHENYL
(2-)23-60-61
BIPHENYL-4-YLAMINE
53-45 Note E
BIPHENYL-4-YLAMINE, SALTS
53-45 Note A, E
BIPHENYL-4,4'-YLENEDIAMINE
53-45-60-61 Note E
BIPHENYL-4,4'-YLENEDIAMINE, SALTS
53-45-60-61 Note A, E
2,2-BIS(ACRYLOYLOXYMETHYL)BUTYL ACRYLATE
(2-)39 Note D
N,N-BIS(3-AMINOPROPYL)METHYLAMINE
(1/2-)26-36/37/39-45
BIS(2-CHLOROETHYL) ETHER
(1/2-)7/9-27-38-45
BIS(CHLOROMETHYL) ETHER
53-45 Note E
O,O-BIS(4-CHLOROPHENYL)
T+
49-25-2643-48/23
608-73-1
T,N
21-25-40-50/53
485-31-4
61-21/22
584-79-2
Xn
22
28434-00-6
Xn,N
21/22-50/53
92-52-4
Xi,N
36/37/38-50/53
92-67-1
45-22
45-22
T,N
45-22-50/53
T,N
45-22-50/53
15625-89-5
Xi
36/38-43
105-83-9
22-23/24-34
111-44-4
T+
10-26/27/28-40
542-88-1
T+
45-10-22-24-26
4104-14-7
T+,N
27/28-50/53
92-87-5
Page 61 of 236
Substance
Safety phrases
BIS(4-FLUOROPHENYL)-METHYL-(1,2,4-TRIAZOL(2-)26-61
4-YLMETHYL)SILANE HYDROCHLORIDE
BIS(HYDROXYLAMMONIUM) SULPHATE
48/22-50
(2-)22-24-37-61
2,5-BIS-(HYDROXYMETHYL)OXOLANE
(2-)39
BIS(8-HYDROXYQUINOLINE) SULPHATE
(2-)36
BIS(2-METHOXYETHYL) PHTHALATE
53-45
BIS(METHOXYTHIOCARBONOYL) DISULPHIDE
(2)
BISPHENOL-A-DIGLYCIDYL ETHER
(2-)28-37/39
BIS(PIPERIDINOTHIOCARBONYL) DISULPHIDE
(2-)24-26-37
BIS(2,2,6,6-TETRAMETHYL-4-PIPERIDYL)SUCCINATE
(2-)26-61
BIS(2,4,6-TRINITROPHENYL)AMINE
80-06-8
Xn
22
3030-47-5
22-24-34
80-43-3
O,Xi
7-36/38
51/53
Xn
22-36/37/38
101-90-6
23/24/25-40-43
2425-79-8
Xn
20/21-36/38-43
17557-23-2
Xi
38-43
1675-54-3
Xi
36/38-43
121-75-5
Xn
22
105254-85-1 C,N
34-43-50/53
91273-04-0
C,N
34-43-51/53
CAS number
Symbol
Risk-phrases
Xi,N
36-51/53
10039-54-0
Xn,N
22-36/38-43-
104-80-3
Xi
36/37/38
134-31-6
Xn
22
117-82-8
61-62
1468-37-7
Xn
22
1675-54-3
Xi
36/38-43
94-37-1
Xi
36/37/38-43
62782-03-0
Xi
36-52/53
131-73-7
E,T+,N
2-26/27/28-33-
Page 62 of 236
119-93-7
T,N
45-22-51/53
2079-00-7
T+
28
10294-33-4
T+,C
14-26/28-35
10294-34-5
T+
14-26/28-34
7637-07-2
T+,C
14-26-35
56073-10-0
T+
27/28-48/24/25
9001-00-7
Xn
36/37/38-42
7726-95-6
T+,C
26-35
79-08-3
T,C
23/24/25-35
108-86-1
Xi,N
10-38-51/53
99688-47-8
Xn,N
43-48/22-50/53
4824-78-6
T,N
21-25-50/53
21609-90-5
T,N
21-25-39/25-
74-96-4
Xn
20/21/22
4463-59-6
Xn
22-52/53
593-60-2
F+,T
45-12
13181-17-4
Xn
22
75-25-2
T,N
23-36/38-51/53
74-83-9
T,N
23-36/37/38-
2104-96-3
Xn
22
4824-78-6
T,N
21-25-50/53
106-94-5
Xn
10-20
100-39-0
Xi
36/37/38
1689-84-5
25-63
1689-99-2
Xn
21/22-63
52-51-7
Xn,N
21/22-37/38-
357-57-3
T+
26/28
Page 63 of 236
BRUCINE, SALTS
(1/2-)13-45 Note A
BUFENCARB
(1/2-)28-36/37-45
BUTANAL
(2-)9-29-33
1,3-BUTADIENE
53-45 Note D
BUTADIENE DIEPOXIDE
36/37/38-40(1/2-)23-24-45
BUTANEDIOLDIGLYCIDYL ETHER
(2-)26-28-37/39
BUTANE
(2-)9-16 Note C
BUTANOL, except tert-BUTYL ALCOHOL
(2-)16 Note C
tert-BUTANOL
(2-)9-16
2-BUTANONE
(2-)9-16-25-33
2-BUTANONE OXIME
(2-)23-24
2-BUTENAL
(1/2-)29-33-45
BUTENE, all isomers
(2-)9-16-33 Note C
2-BUTOXYETHANOL
(2-)24/25
2-(2-BUTOXYETHOXY)ETHANOL
(2-)26
2-(2-BUTOXYETHOXY)ETHYL THIOCYANATE
(1/2-)13-36/37-45
2-BUTOXYETHYL ACETATE
(2-)24
3-BUTOXY-2-PROPANOL
(2)
1-(2-BUTOXYPROPOXY)PROPAN-2-OL
(2)
n-BUTYL ACETATE
(2)
sec-BUTYL ACETATE
(2-)16-23-29-33 Note C
Page No.
6
18/11/96
24/25
123-72-8
11
106-99-0
F+,T
45-12
1464-53-5
23/24/2542/43
2425-79-8
Xn
20/21-36/38-43
106-97-8
F+
12
71-36-3(n)
Xn
10-20
75-65-0
F,Xn
11-20
78-93-3
F,Xi
11-36/37
96-29-7
Xi
36-43
123-73-9
F,T
11-23-36/37/38
F+
12
111-76-2
Xn
20/21/22-37
112-34-5
Xi
36
112-56-1
10-24/25
112-07-2
Xn
20/21
5131-66-8
Xi
36/38
24083-03-2
Xn
21/22
123-86-4
10
105-46-4
11
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
tert-BUTYL ACETATE
(2-)16-23-29-33 Note C
ISOBUTYL ACETATE
(2-)16-23-29-33 Note C
n-BUTYL ACRYLATE
(2-)9 Note D
tert-BUTYL ALCOHOL
540-88-5
11
110-19-0
11
141-32-2
Xi
10-36/37/38-43
75-65-0
F,Xn
11-20
Page 64 of 236
71-36-3 (n) Xn
10-20
109-73-9
F,C
11-20/21/22-35
13952-84-6
F,C,N
11-20/22-35-50
3775-90-4
Xi
36/38-43
109-21-7
10
109-69-3
11
592-34-7
10-23-34
299-86-5
Xn,N
21/22-50/53
3457-61-2
O,Xi
7-38
F,Xi,N
11-36-51/53
3457-61-2
O,Xi
7-38
88-85-7
T,N
61-62-24/25-
1420-07-1
61-24/25-36-44
973-21-7
25
485-31-4
61-21/22
19485-03-1
21-34-43
1070-70-8
21-34-43
2426-08-6
Xn
20-43
106-35-4
Xn
10-20-36
592-84-7(n) F
11
2426-08-6
Xn
20-43
112-07-2
Xn
20/21
97-88-1
Xi
10-36/37/38-43
591-78-6
F,T
11-48/23
26576-84-1
Xn
22-52/53
924-43-6
F,Xn
11-20/22
Page 65 of 236
540-80-7
F,Xn
11-20/22
591-01-2(n) -
10
110-65-6
25-34
123-72-8
11
110-69-0
22-24-36
107-92-6
34
109-74-0
10-23/24/25
141-75-3
F,C
11-34
10108-64-2
45-48/23/25
Xn
20/21/22
542-83-6
T+
26/27/28-32-
7790-79-6
23/25-33-40
17010-21-8
23/25-33-40
4464-23-7
23/25-33-40
17010-21-8
23/25-33-40
7790-80-9
23/25-33-40
1306-19-0
49-22-48/23/25
10124-36-4
49-22-48/23/25
1306-23-6
22-40-48/23/25
58-08-2
Xn
22
7440-70-2
15
75-20-7
15
10043-52-4
Xi
36
13765-19-0
T,N
45-22-50/53
156-62-7
Xn
22-37-41
CAS number
Symbol
Risk-phrases
Page 66 of 236
T+
28-32
15
O,C
8-31-34
C,N
34-51/53
F,T+
15/29-28
Xi
31-36/37/38
Xi
31-36/37/38
Xn
22-36/37/38
T,N
21-25-37/38-
Xn
20/22-36/37/38
45-43
Xn
36-40-43
F,T
45-11-22
21-25-36/38-43
Xn
22
Xn
40
T+
26/28
Xn,N
22-36-40-51/53
Xn,N
22-36-40-51/53
F,T
11-36/38-
F+,T
61-12-23-48/23
T,N
23/24/25-40-
CARBONYL CHLORIDE
(1/2-)9-26-36/37/39-45
4,4'-CARBONYLDI(PHTHALIC ANHYDRIDE)
(2-)25
CARBOPHENOTHION
(1/2-)28-36/37-45-60-61
CARTAP HYDROCHLORIDE
(2-)36/37
CAUSTIC POTASH
(1/2-)26-37/39-45
CAUSTIC SODA
75-44-5
T+
52/53-59
26-34
2421-28-5
Xi
36/37
786-19-6
T,N
24/25-50/53
15263-52-2
Xn
21/22
1310-58-3
35
1310-73-2
35
Page 67 of 236
37329-65-0
Xn
42
9012-54-8
Xn
42
9012-54-8
Xn
42
11
9004-70-0
1-3
302-17-0
25-36/38
95-06-7
45-22
15879-93-3
Xn
20/22
127-65-1
Xi
36/37/38
118-75-2
Xi,N
36/38-50/53
57-74-9
Xn,N
21/22-40-50/53
143-50-0
24/25-40
6164-98-3
Xn
21/22-40
19750-95-9
Xn
22-40
115-27-5
Xi
36/37/38
85-34-7
Xn
22
80-06-8
Xn
22
14437-17-3
Xn
21/22
80-33-1
Xn
22-38
470-90-6
T+,N
24-28-50/53
7782-50-5
T,N
23-36/37/38-50
24934-91-6
T+
27/28
999-81-5
Xn
21/22
79-11-8
T,N
25-34-50
107-14-2
23/24/25
79-04-9
34-37
95-06-7
45-22
T,N
23/24/25-33-
Page 68 of 236
T+,N
26/27/28-33-
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
2-CHLOROBENZALDEHYDE
(1/2-)26-45
o-CHLOROBENZALDEHYDE
(1/2-)26-45
CHLOROBENZENE
(2-)24/25-61
CHLOROBENZILATE
(2)
2-CHLOROBENZONITRILE
(2-)23
2-CHLOROBUTA-1,3-DIENE
(2-)16 Note D
1-CHLOROBUTANE
(2-)9-16-29
4-CHLOROBUT-2-YNYL 3-CHLOROPHENYLCARBAMATE
(2-)24-36/37
CHLOROCRESOL
(2-)26-36/37/39-61
4-CHLORO-m-CRESOL
(2-)26-36/37/39-61
3-CHLORO-6-CYANO-BICYCLO(2.2.1)HEPTAN-2-ONE(1/2-)28-36/37-45
O(N-METHYLCARBAMOYL)OXIME
2-(4-CHLORO-6-ETHYLAMINO-1,3,5-TRIAZINE-2(2-)37
YLAMINO)-2-METHYLPROPIONITRILE
2-CHLORO-1-(2,4-DICHLOROPHENYL)VINYL DIETHYL
(1/2-)28-36/37-45-60-61
PHOSPHATE
2-CHLORO-2-DIETHYLCARBAMOYL-1-METHYLVINYL
(1/2-)23-36/37-45-60-61
DIMETHYL PHOSPHATE
2-CHLORO-4-DIMETHYLAMINO-6-METHYLPYRIMIDINE
(1/2-)36/37-45
CHLORODIMETHYL ETHER
53-45 Note E
CHLORODINITROBENZENE
50/53
(1/2-)28-36/37-45-60-61 Note C
1-CHLORO-2,3-EPOXYPROPANE
23/24/25-34-43
53-45 Note E
CHLOROETHANE
(2-)9-16-33-36/37-61
2-CHLOROETHANOL
(1/2-)7/9-28-45
2-CHLOROETHYL CHLOROPROPYL 2-CHLOROETHYL(2)
PHOSPHONATE and 2-CHLOROETHYL CHLOROPROPYL
89-98-5
34
89-98-5
34
108-90-7
Xn,N
10-20-51/53
510-15-6
Xn
22
873-32-5
Xn
21/22-36
126-99-8
F,Xn
11-20/22-36
109-69-3
11
101-27-9
Xn
22-43
59-50-7
Xn,N
21/22-41-43-50
59-50-7
Xn,N
21/22-41-43-50
15271-41-7
T+
24-28
21725-46-2
Xn
22
470-90-6
T+,N
24-28-50/53
13171-21-6
T+,N
24-28-40-50/53
535-89-7
T+
28
107-30-2
F,T
45-11-20/21/22
T,N
23/24/25-33-
106-89-8
45-10-
75-00-3
F+,Xn
12-40-52/53
107-07-3
T+
26/27/28
Xn
22
Page 69 of 236
F+,T
45-12
Xn
21/22
Xn
22-38-40-
10-23-34
10-23-34
Xn
22-36-43
F+,Xn
12-40-48/20
51/53
T+,N
21-28-50/53
F,T
45-11-20/21/22
Xn,N
21/22-41-43-50
Xn
22
Xn
22-38-41
F,C,N
11-20/22-34-
T+,N
26/27/28-33-
Xn,N
22-51/53
23/24/25-33
23/24/25-33
50/53
Xn
20/21/22
Xn
20/21/22
Xn
20/22
T,N
21-25-50/53
F,Xn
11-20/21/22
F,Xn
11-20/21/22
F,Xn
11-20/21/22
Xn,N
10-20/22-50-58
Page 70 of 236
Substance
Safety phrases
3691-35-8
T+
23-27/28-
Xn
20/21/22
122-88-3
Xn
22
5834-96-8
Xn
20/22
CAS number
Symbol
Risk-phrases
Xn
22-36
50/53
Xi,N
36-50/53
Xn
22-40
25
Xn
22
T+
23-27/28-
C,N
34-43-48/22-
T,N
24/25-50/53
T+,N
24-28-50/53
T+
22-26-36/37/38
F,Xn
11-20/22-36
F,Xn
11-20/21/22
F,Xn
11-20/21/22
F,T+,N
11-26-50
22-35
14-35-37
4-CHLOROPHENYL BENZENESULPHONATE
80-38-6
(2-)24-26
(CHLOROPHENYL)(CHLOROTOLYL)METHANE
60-61
2-(4-(3-(4-CHLOROPHENYL)-4,5106359-93-7
(2-)26-60-61
DIHYDROPYRAZOLYL)PHENYLSULPHONYL)ETHYLDIMETHYLAMMONIUM HYDROGEN PHOSPHONATE
3-(4-CHLOROPHENYL)-1,1-DIMETHYLUREA
150-68-5
(2-)36/37
4-(2-CHLOROPHENYLHYDRAZONO)-3-METHYL-55707-69-7
(1/2-)22-24-36/37-45
ISOXAZOLONE
3-(4-CHLOROPHENYL)-1-METHOXY-1-METHYLUREA
1746-81-2
(2-)22
2-[2-(4-CHLOROPHENYL)-2-PHENYLACETYL]INDAN3691-35-8
48/24/25
(1/2-)36/37-45
1,3-DIONE
2-(4-(3-(4-CHLOROPHENYL)-2-PYRAZOLIN-1-YL)
50/53
(1/2-)24-26-28-37/39-45-60-61
PHENYLSULPHONYL)ETHYLDIMETHYLAMMONIUM FORMATE
S-(4-CHLOROPHENYLTHIOMETHYL) O,O-DIETHYL
786-19-6
(1/2-)28-36/37-45-60-61
PHOSPHORODITHIOATE
2-CHLORO-1-PHTHALIMIDOETHYL O,O-DIETHYL
10311-84-9
(1/2-)28-36/37-45-60-61
PHOSPHORODITHIOATE
CHLOROPICRIN
76-06-2
(1/2-)36/37-38-45
CHLOROPRENE
126-99-8
(2-)16 Note D
1-CHLOROPROPANE
540-54-5
(2-)9-29 Note C
2-CHLOROPROPANE
75-29-6
(2-)9-29 Note C
3-CHLOROPROPENE
107-05-1
(1/2-)16-29-33-45-61 Note D
2-CHLOROPROPIONIC ACID
598-78-7
(1/2-)23-26-28-36-45
CHLOROSULPHONIC ACID
7790-94-5
Page 71 of 236
7790-94-5
14-35-37
1897-45-6
Xn
40
95-49-8
Xn,N
20-51/53
108-41-8
Xn,N
20-51/53
106-43-3
Xn,N
20-51/53
25168-05-2
Xn,N
20-51/53
100-44-7
22-23-37/38-
6164-98-3
Xn
21/22-40
19750-95-9
Xn
20-40
94-74-6
Xn
22-38-41
T,N
22-41-43-
79456-26-1
Xn
22-52/53
28260-61-9
E,T+
2-26/27/28
115-78-6
21-25-36/38
2921-88-2
T,N
24/25-50/53
1918-13-4
Xn
22
500-28-7
Xn
20/21/22
21923-23-9
T+
24-28
64-86-8
T+
26/28
24613-89-6
O,T,C,N
45-8-35-43-
14977-61-8
O,T,C,N
49-46-8-35-43-
24613-89-6
O,T,C,N
45-8-35-43-
T,N
49-43-50/53
1333-82-0
O,T,C,N
49-8-25-35-43-
14977-61-8
O,T,C,N
49-46-8-35-43-
1937-37-7
45-63
2602-46-2
45-63
Page 72 of 236
Substance
Safety phrases
16071-86-6
45
573-58-0
45-63
492-80-8
Xn,N
22-36-40-51/53
25402-06-6
Xn
22
121-20-0
Xn
22
5392-40-5
Xi
38-43
51337-71-4
Xn
22
CAS number
Symbol
Risk-phrases
Xi,N
41-51/53
Xn
42/43
Xn
22-43
Xi
43
T+
26/28
Xn
43
Xn
22
50/53
Xn
10-22
Xn
22
Xn
22-36/38
Xn
48/22
25-48/25
T+,N
21-28-50/53
T+
27/28-48/24/25
25
Xn
22
CLOPYRALID
1702-17-6
(2-)26-39-61
COBALT
7440-48-4
(2-)22-24-37
COBALT OXIDE
1307-96-6
(2-)24-37
COBALT SULPHIDE
1317-42-6
(2-)24-37
COLCHICINE
64-86-8
(1/2-)13-45
COLOPHONY
8050-09-7
(2-)24-37
COPPER CHLORIDE
7758-89-6
(2-)22
COPPER(I) O,O-DIISOPROPYL PHOSPHORODITHIOATE
60-61
and COPPER(I) O-ISOPROPYL O-(4-METHYLPENT2-YL) PHOSPHORODITHIOATE and COPPER(I)
O,O-BIS(4-METHYLPENT-2-YL) PHOSPHORODITHIOATE
COPPER NAPHTHENATE
1338-02-9
(2)
COPPER (I) OXIDE
1317-39-1
(2-)22
COPPER SULPHATE
7758-98-7
(2-)22
COUMACHLOR
81-82-3
(2-)37
COUMAFURYL
117-52-2
(1/2-)37-45
COUMAPHOS
56-72-4
(1/2-)28-36/37-45-60-61
COUMATETRALYL
5836-29-3
(1/2-)36/37-45
COUMITHOATE
572-48-5
(1/2-)28-36/37-45
4-CPA
122-88-3
Page 73 of 236
24/25-34
26447-14-3
Xi
38
535-89-7
T+
28
123-73-9
F,T
11-23-36/37/38
7700-17-6
24/25
299-86-5
Xn,N
21/22-50-53
15096-52-3
20/22-48/23/25
98-82-8
Xi
10-37
80-15-9
O,C
7-20/22-34
572-48-5
25
420-04-2
21-25-36/38-43
21725-46-2
Xn
22
T+
26/27/28-32
3734-95-0
T+
24-28
13067-93-1
21-25-36-39/25
460-19-5
F,T
11-23
2636-26-2
Xn,N
21/22-50/53
2636-26-2
Xn,N
21/22-50/53
75-86-5
T+,N
26/27/28-50
3734-95-0
T+
24-28
108-77-0
Xi
36/37/38
15506-53-3
11
110-82-7
11
85-42-7
Xi
108-93-0
108-94-1
Xn
10-20
12262-58-7
E,C
2-7-22-34
85-43-8
Xi
36/37
36/37/38
Xn
Page 74 of 236
CYCLOHEXYL ACRYLATE
(2) Note D
CYCLOHEXYLAMINE
(1/2-)36/37/39-45
2-CYCLOHEXYL-4,6-DINITROPHENOL
(1/2-)13-45
CYCLOOCT-4-EN-1-YL METHYL CARBONATE
(2-)24-37
CYCLOPENTANE
(2-)9-16-29-33
CYCLOPENTANE-1,2,3,4-TETRACARBOXYLIC
(2-)25
DIANHYDRIDE
CYCLOPENTANONE
(2-)23
CYCLOPROPANE
(2-)9-16-33
CYHEXATIN
(2-)13
CHYMOTRYPSIN
(2-)22-24-26-36/37
2,4-D
(2-)36/37
Page No.
11
18/11/96
3066-71-5
Substance
Safety phrases
2,4-D, SALTS and ESTERS
(2-)13 Note A
DALAPON
(2-)26-39
DAMINOZIDE
(2-)36/37
DAPSONE
(2-)22
DAZOMET
(2-)15-22-24
2,4-DB
(2-)36/37
2,4-DB, SALTS
(2-)13 Note A
DDT
50/53
(1/2-)22-36/37-45-60-61
DECACHLOROPENTACYCLO
(1/2-)22-36/37-45
(5.2.1.02,6.03,9.05,8) DECAN-4-ONE
DECARBOFURAN
(1/2-)13-36/37-45
DEHYDRACETIC ACID
(2)
DEMEPHION-O
(1/2-)28-36/37-45
DEMEPHION-S
(1/2-)28-36/37-45
DEMETON
108-91-8
10-21/22-34
131-89-5
23/24/25
87731-18-8
Xi
43
287-92-3
11
6053-68-5
Xi
36/37
120-92-3
Xi
10-36/38
75-19-4
F+
12
13121-70-5
Xn
20/21/22
9004-07-3
Xn
36/37/38-42
94-75-7
Xn
22-36/37/38
CAS number
Symbol
Risk-phrases
Xn
20/21/22
75-99-0
Xn
22-38-41
1596-84-5
Xn
40
80-08-0
Xn
22
533-74-4
Xn
22-36
94-82-6
Xn
21/22
Xn
20/21/22
50-29-3
T,N
25-40-48/25-
143-50-0
24/25-40
1563-67-3
23/24/25
520-45-6
Xn
22
682-80-4
T+
24-28
2587-90-8
T+
24-28
8065-48-3
T+,N
27/28-50
Page 75 of 236
298-03-3
T+,N
27/28-50
867-27-6
25
126-75-0
T+
27/28
919-86-8
T,N
24/25-51/53
17040-19-6
21-25
149-26-7
Xn
22-38-41
1014-69-3
Xn
21/22
123-42-2
F,Xi
11-36
123-42-2
F,Xi
11-36
613-35-4
Xn
20/21/22
10311-84-9
T+,N
24-28-50/53
2303-16-4
Xn
22-40
93-71-0
Xn
21/22-36/38
131-17-9
Xn
22
92-87-5
T,N
45-22-50/53
101-77-9
T,N
45-20/21/22-
80-08-0
Xn
48/20/21-51/53
22
107-15-3
10-21/22-34-
6369-59-1
T,N
20/21-25-43-
78-57-9
Xn
22-52/53
Xn,N
22-41-42/43-50
45-22
45-22
112-24-3
21-34-43-52/53
333-41-5
Xn,N
22-50/53
334-88-3
45
53-70-3
45
94-36-0
E,Xi
2-7-36-43
119-90-4
Page 76 of 236
1,2-DIBROMO-3-CHLOROPROPANE
48/20/2253-45-61 Note E
96-12-8
O-1,2-DIBROMO-2,2-DICHLOROETHYL
(2-)36/37
DIMETHYL PHOSPHATE
1,2-DIBROMOETHANE
36/37/3853-45-61 Note E
300-76-5
Xn
52/53
21/22-36/38
106-93-4
T,N
45-23/24/25-
3,5-DIBROMO-4-HYDROXYBENZALDEHYDE
(2-)25
O-(2,4-DINITROPHENYL) OXIME
3,5-DIBROMO-4-HYDROXYBENZONITRILE
(1/2-)36/37-45
DIBROMOMETHANE
(2-)24-61
DI-n-BUTYLAMINE
(2)
DI-sec-BUTYLAMINE
(2)
DIBUTYL ETHER
(2)
DI-n-BUTYL ETHER
(2)
DI-tert-BUTYL PEROXIDE
(2-)3/7-14-16-36/37/39
DIBUTYLTIN HYDROGEN BORATE
48/25-50/53 (1/2-)22-26-36/37-45-60-61
DICHLOBENIL
(2-)36/37
DICHLOFENTHION
(2)-60-61
Page No.
12
18/11/96
13181-17-4
Xn
51/53
22
1689-84-5
25-63
74-95-3
Xn
20-52/53
111-92-2
Xn
10-20/21/22
626-23-3
Xn
10-20/21/22
142-96-1
Xi
10-36/37/38
142-96-1
Xi
10-36/37/38
110-05-4
O,F
7-11
75113-37-0
T,N
21/22-41-43-
1194-65-6
Xn
21
97-17-6
Xn,N
22-50/53
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
DICHLOFLUANID
(2-)22-24-60-61
DICHLONE
(2-)26
DICHLOROACETIC ACID
(1/2-)26-45
DICHLOROACETYL CHLORIDE
(1/2-)9-26-45
DICHLOROACETYLENE
(2-)36/37
S-2,3-DICHLOROALLYL DIISOPROPYLTHIOCARBAMATE
(2-)25-36/37
DICHLOROANILINE
50/53
(1/2-)28-36/37-45-60-61 Note C
1,2-DICHLOROBENZENE
50/53
(2-)23-60-61
1,3-DICHLOROBENZENE
(2-)61
1,4-DICHLOROBENZENE
1085-98-9
Xi,N
36-43-50/53
117-80-6
Xn
22-36/38
79-43-6
35
79-36-7
35
7572-29-4
E,Xn
2-40-48/20
2303-16-4
Xn
22-40
T,N
23/24/25-33-
95-50-1
Xn,N
22-36/37/38-
541-73-1
Xn,N
22-51/53
106-46-7
Xn
22-36/38
Page 77 of 236
Page 78 of 236
1,1-DICHLORO-1-NITROETHANE
(1/2-)26-45
DICHLOROPHEN
(2-)26
2,4-DICHLOROPHENOL
(1/2-)26-36/37/39-45-61
2,4-DICHLOROPHENOXYACETIC ACID
(2-)36/37
4-(2,4-DICHLOROPHENOXY) BUTYRIC ACID
(2-)36/37
2-(2,4-DICHLOROPHENOXY)ETHYL HYDROGENSULPHATE
(2-)26
2-(2,4-DICHLOROPHENOXY) PROPIONIC ACID
(2-)26-36/37
O-(2,4-DICHLOROPHENYL) O,O-DIETHYL
(2)-60-61
PHOSPHOROTHIOATE
3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA
(2-)22-37
1-(3,4-DICHLOROPHENYLIMINO) THIOSEMICARBAZIDE
(1/2-)22-36/37-45
3-(3,4-DICHLOROPHENYL)-1-METHOXY-1-METHYLUREA
(2-)36/37
S-(2,5-DICHLOROPHENYLTHIOMETHYL) O,O-DIETHYL
(1/2-)13-45-60-61
PHOSPHORODITHIOATE
1,2-DICHLOROPROPANE
(2-)16-24
1,3-DICHLORO-2-PROPANOL
53-45 Note E
1,1-DICHLOROPROPENE
(1/2-)16-29-33-45-61
1,3-DICHLOROPROPENE
36/37/38(1/2-)36/37-45-60-61 Note D, C
594-72-9
97-23-4
Xn
22-36
120-83-2
C,N
21/22-34-51/53
94-75-7
Xn
22-36/37/38
94-82-6
Xn
21/22
149-26-8
Xn
22-38-41
120-36-5
Xn
21/22-38-41
97-17-6
Xn,N
22-50/53
330-54-1
Xn
48/22
5836-73-7
T+
28
330-55-2
Xn
40
2275-14-1
T,N
23/24/25-50/53
78-87-5
F,Xn
11-20/22
96-23-1
45-21-25
563-58-6
F,T
11-25-52/53
542-75-6
T,N
10-20/21-25-
(Z)-1,3-DICHLOROPROPENE
36/37/38(1/2-)36/37-45-60-61 Note D, C
10061-01-5
T,N
43-50/53
10-20/21-25-
3',4'-DICHLOROPROPIONANILIDE
(2-)22
Page No.
13
18/11/96
709-98-8
Xn
43-50/53
22
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
2,2-DICHLOROPROPIONIC ACID
(2-)26-39
3,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID
(2-)26-39-61
2,4-DICHLORO-I-(PYRIMIDIN-5-YL)
(2)
BENZHYDRYL ALCOHOL
3,7-DICHLOROQUINOLINE-8-CARBOXYLIC ACID
(2-)24-37
3,5-DICHLORO-4-(1,1,2,2-TETRAFLUOROETHOXY)
(2-)24/25-26-57-60-61
75-99-0
Xn
22-38-41
1702-17-6
Xi,N
41-51/53
26766-27-8
Xn
22
84-087-01-4 Xi
43
104147-32-2 Xn,N
22-50/53
Page 79 of 236
1918-13-4
Xn
22
98-87-3
22-23-36/37-
2782-57-2
O,Xn
8-22-31-36/37
2893-78-9
O,Xn
8-22-31-36/37
2244-21-5
62-73-7
24/25
7076-53-1
23/24/25
120-36-5
Xn
21/22-38-41
Xn
20/21/22
62-73-7
24/25
24613-89-6
O,T,C,N
45-8-35-43-
51338-27-3
Xn
22
115-32-2
Xn
21/22-38-43
66-76-2
22-48/25
141-66-2
T+,N
24-28-50/53
80-43-3
O,Xi
7-36/38
3347-22-6
Xn
22
101-83-7
C,N
22-34-50/53
3129-91-7
Xn
20/22
538-75-0
22-24-41-43
5124-30-1
23-36/37/38-
60-57-1
T+,N
25-27-40-
1464-53-5
23/24/2542/43
111-42-2
Xi
36/38
Xn
22
105-57-7
F,Xi
11-36/38
14816-18-3
Xn
22
Page 80 of 236
DIETHYLAMINE
(1/2-)3-16-26-29-36/37/39-45
2-DIETHYLAMINOETHANOL
(2-)28
2-DIETHYLAMINOETHYL METHACRYLATE
(2-)26 Note D
2,6-DIETHYLANILINE
(2-)23-34
N,N-DIETHYLANILINE
51/53
(1/2-)28-37-45-61
DIETHYLCARBAMOYL CHLORIDE
36/37/38-40
(2-)26-36/37
N,N-DIETHYL-1,3-DIAMINOPROPANE
(1/2-)26-36/37/39-45
O,O-DIETHYL O-2-DIETHYLAMINO-6(1/2-)23-36/37-45-60-61
METHYLPYRIMIDIN-4-YL PHOSPHOROTHIOATE
DIETHYLENE GLYCOL DIACRYLATE
(1/2-)28-39-45 Note D
DIETHYLENE GLYCOL DINITRATE
(1/2-)33-35-36/37-45
DIETHYLENETRIAMINE
(1/2-)26-36/37/39-45
DIETHYL ETHER
(2-)9-16-29-33
DIETHYL(ETHYLDIMETHYLSILANOLATO)ALUMINIUM
(1/2-)6-16-30-36/39-43-45
O,O-DIETHYL S-[2-(ETHYLSULPHINYL)ETHYL]
(1/2-)28-36/37-45
PHOSPHORODITHIOATE
O,O-DIETHYL-O-[2-(ETHYLTHIO)ETHYL] PHOSPHORO(1/2-)28-36/37-45-61
THIOATE
O,O-DIETHYL-S-[2-(ETHYLTHIO)ETHYL] PHOSPHORO(1/2-)28-36/37-45-60-61
DITHIOATE
DIETHYL-S-[2-(ETHYLTHIO)ETHYL] PHOSPHORO(1/2-)28-36/37-45
THIOATE
O,O-DIETHYL ETHYLTHIOMETHYL
(1/2-)28-36/37-45
PHOSPHORODITHIOATE
O,O-DIETHYL ISOPROPYLCARBAMOYLMETHYL
(1/2-)28-36/37-45
PHOSPHORODITHIOATE
Page No.
14
18/11/96
109-89-7
100-37-8
Xi
36/37/38
105-16-8
Xn
20-36/38-43
579-66-8
Xn
22
91-66-7
T,N
23/24/25-33-
88-10-8
Xn
20/22-
104-78-9
10-21/22-34-43
23505-41-1
T,N
21-25-50/53
4074-88-8
24-36/38-43
693-21-0
E,T+
3-26/27/28-33
111-40-0
21/22-34-43
60-29-7
F+
12-19
55426-95-4
F,C
14/15-17-35
2497-07-6
T+
24-28
298-03-3
T+,N
27/28-50
298-04-4
T+,N
27/28-50/53
126-75-0
T+
27/28
298-02-2
T+
27/28
2275-18-5
T+
27/28
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
O,O-DIETHYL-O-2-ISOPROPYL-6-METHYL(2-)24/25-60-61
PYRIMIDIN-4-YL PHOSPHOROTHIOATE
DIETHYL KETONE
(2-)9-16-33
O,O-DIETHYL-O-(4-METHYLCOUMARIN-7-YL)
(1/2-)13-28-45
333-41-5
Xn,N
22-50/53
96-22-0
11
299-45-6
T+
26/27/28
Page 81 of 236
950-10-7
T+,N
27/28-51/53
108-34-9
T+
26/27/28
115-90-2
T+,N
27/28-50/53
56-38-2
T+,N
27/28-50/53
95-92-1
Xn
22-36
2642-71-9
T+
24-28
93-05-0
25-34
64-67-5
45-46-
572-48-5
25
134-62-3
Xn
22-36/38
2921-88-2
T,N
24/25-50/53
56073-07-5
T+
28-48/25
43222-48-6
Xn
22
71-63-6
23/25-33
693-21-0
E,T+
3-26/27/28-33
2764-72-9
24/25-36/37/38
1563-66-2
T+
26/28
950-37-8
T+,N
21-28-50/53
1563-67-3
23/24/25
120-80-9
Xn
21/22-36/38
123-31-9
Xn
20/22
107-39-1
11
108-83-8
Xi
10-37
91-08-7
23-36/37/38-42
110-97-4
Xi
36
Page 82 of 236
DI-ISOPROPYL ETHER
(2-)9-16-33
DI-ISOPROPYL KETONE
(2-)16-23
O,O-DIISOPROPYL 2-PHENYLSULPHONYL(2-)24-36
AMINOETHYL PHOSPHORODITHIOATE
N,N'-DIISOPROPYLPHOSPHORODIAMINIC FLUORIDE
(1/2-)13-45
DIKETENE
(2-)3 Note D
DILAUROYL PEROXIDE
(2-)3/7-14-36/37/39
DILITHIUM 6-ACETAMIDO-4-HYDROXY-3-(4-((2(2-)24-37
SULPHONATOOXY)ETHYLSULPHONYL)PHENYLAZO)
NAPHTHALENE-2-SULPHONATE
DIMEFOX
(1/2-)23-28-36/37-38-45
DIMEPRANOL
(1/2-)23-26-36-45
DIMERCURY DICHLORIDE
(2-)13-24/25-46
DIMETAN
(1/2-)36/37-45
DIMETHOATE
(2-)36/37
3,3'-DIMETHOXYBENZIDINE
53-45 Note E
3,3'-DIMETHOXYBENZIDINE, SALTS
53-45 Note A, E
1,1-DIMETHOXYETHANE
(2-)9-16-33
1,2-DIMETHOXYETHANE
(2-)24/25
DIMETHYL ACETAL
(2-)9-16-33
N,N-DIMETHYLACETAMIDE
(2-)26-28-36
O,S-DIMETHYL ACETYLPHOSPHORAMIDOTHIOATE
(2-)36
2-DIMETHYLAMINO-5,6-DIMETHYLPYRIMIDIN-4-YL
(1/2-)22-37-45
DIMETHYLCARBAMATE
2-DIMETHYLAMINOETHANOL
(2-)28
Page No.
15
18/11/96
108-20-3
565-80-0
11
741-58-2
Xn
22
371-86-8
T+
39/26/27/28
674-82-8
Xn
10-20
105-74-8
Xi
43
115-26-4
T+
27/28
108-16-7
10-22-34
10112-91-1
Xn
22-36/37/38
122-15-6
25
60-51-5
Xn
21/22
119-90-4
45-22
45-22
534-15-6
11
110-71-4
Xn
10-19-20
534-15-6
11
127-19-5
Xn
20/21-36
30560-19-1
Xn
22
23103-98-2
25
108-01-0
Xi
10-36/37/38
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
2-DIMETHYLAMINOETHYLAMINE
(1/2-)16-23-26-28-36-45
3-DIMETHYLAMINOMETHYLENEAMINOPHENYL
(1/2-)22-36/37-45
METHYLCARBAMATE
2-DIMETHYLAMINOETHYL METHACRYLATE
108-00-9
F,C
11-21/22-35
22259-30-9
T+
28
2867-47-2
Xn
21/22-36/38-43
Page 83 of 236
31506-43-1
Xi
41
1596-84-5
Xn
40
2032-59-9
24/25
315-18-4
T+
21-28
121-69-7
T,N
23/24/25-40-
78-67-1
E,Xn
2-11-20/22
2836-04-6
23/24/25
99-98-9
23/24/25
119-93-7
T,N
45-22-51/53
T,N
45-22-51/53
2810-74-4
Xn
20/21/22
22961-82-6
Xi
41
80-15-9
O,C
7-20/22-34
4685-14-7
24/25-36/37/38
79-44-7
45-22-23-
644-64-4
21-25
616-38-6
11
10357-99-0
Xn,N
43-48/22-51/53
589-90-2
11
109-55-7
10-22-34-43
75-78-5
F,Xi
11-36/37/38
141-66-2
T+,N
22-28-50/53
957-51-7
Xn
22
115-10-6
F+
12
68-12-2
61-20/21-36
68-12-2
61-20/21-36
108-83-8
Xi
10-37
540-73-8
45-23/24/25
Page 84 of 236
57-14-7
F,T
45-11-23/25-34
1739-84-0
Xn
22-38-41
2275-23-2
T,N
21-25-50
60-51-5
Xn
21/22
1113-02-6
T,N
21-25-50
6923-22-4
T+,N
24-28-50/53
6864-37-5
T,C,N
22-23/24-35-
55-38-9
T,N
21-25-50/53
3254-63-5
T+
27/28
122-14-5
Xn,N
22-50/53
144-41-2
T,N
23/24/25-50/53
298-00-0
T+
24-28
62-75-9
T+,N
45-25-26-
22-35
86-50-0
T+
24-28
122-15-6
25
565-80-0
11
10265-92-6
T+,N
24-28-36-50
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
O,O-DIMETHYL S-PHTHALIMIDOMETHYL
(2-)22-36/37
PHOSPHORODITHIOATE
2,2-DIMETHYL PROPANE
732-11-6
Xn
21/22
463-82-1
F+
12
Page 85 of 236
1000-78-8
Xi
38-43
13360-57-1
T+
45-21/22-26-34
77-78-1
T+
45-25-26-34
23/24/25-33-
52-68-6
Xn
22-43
299-84-3
Xn
21/22
24602-86-6
Xn
21/22
2223-82-7
24-36/38-43
644-64-4
21-25
1468-37-7
Xn
22
131-89-5
23/24/25
23/24/25
1314-06-3
49-43
97-02-9
T+,N
26/27/28-33-
25154-54-5
T+,N
26/27/28-33-
2980-64-5
T+
26/27/28-33
5787-96-2
23/24/25-33
2312-76-7
23/24/25-33
10544-72-6
T+
26-34
39300-45-3
Xn
22-38
25550-58-7
23/24/25-33
23/24/25-33
25321-14-6
23/24/25-33
973-21-7
25
39300-45-3
Xn
22-38
63919-26-6
Xn
22
8069-76-9
Xn
22
Page 86 of 236
8,9-DINORBORN-5-ENE-2,3-DICARBOXYLIC
(2-)39 Note C
ANHYDRIDE
DINOSAM
(1/2-)13-45
DINOSAM, SALTS and ESTERS
(1/2-)13-45 Note A
DINOSEB
36-44-50/53 53-45-60-61 Note E
DINOSEB, SALTS and ESTERS
36-44
53-45 Note A, E
DINOTERB
36-44
53-45 Note E
DINOTERB, SALTS and ESTERS
53-45 Note A, E
DIOXACARB
(1/2-)37-45
1,4-DIOXANE
(2-)16-36/37
1,4-DIOXAN-2,3-DIYL-O,O,O',O'-TETRAETHYL
(1/2-)28-36/37-45
DI(PHOSPHORODITHIOATE)
DIOXATHION
(1/2-)28-36/37-45
1,3-DIOXOLANE
(2-)16
2-(1,3-DIOXOLAN-2-YL)PHENYL METHYLCARBAMATE
(1/2-)37-45
N-(4-(4-(2,5-DIOXOPYRROL(2-)24-37-60-61
1-YL)BENZYL)PHENYL)ACETAMIDE
DIPENTENE
(2-)28
DIPHACINONE
(1/2-)36/37-45
DIPHENAMID
(2)
DIPHENYL
(2-)23-60-61
DIPHENYLAMINE
50/53
(1/2-)28-36/37-45-60-61
1,2-DIPHENYLHYDRAZINE
53-45 Note E
DIPHENYLMETHANEDIISOCYANATE, isomers
(2-)26-28-38-45 Note C
and homologues
DIPHENYLMETHANE-2,2'-DIISOCYANATE
(2-)26-28-38-45 Note C
DIPHENYLMETHANE-2,4'-DIISOCYANATE
(2-)26-28-38-45 Note C
DIPHENYLMETHANE-4,4'-DIISOCYANATE
(2-)26-28-38-45 Note C
DIPICRYLAMINE, AMMONIUM SALT
51/53
(1/2-)28-36/37-45-61
Page No.
17
18/11/96
Substance
Safety phrases
23/24/25
23/24/25
T,N
61-62-24/25-
61-62-24/25-
61-23/24/25-
61-23/24/25
6988-21-2
25
123-91-1
F,Xn
11-19-36/37-40
78-34-2
T+
24-26/28
78-34-2
T+
24-26/28
646-06-0
11
6988-21-2
25
Xi,N
43-50/53
138-86-3
Xi
10-38
82-66-6
T+
28-48/23/24/25
957-51-7
Xn
22
92-52-4
Xi,N
36/37/38-50/53
122-39-4
T,N
23/24/25-33-
122-66-7
45-22
9016-87-9
Xn
20-36/37/38-42
2536-05-2
Xn
20-36/37/38-42
5873-54-1
Xn
20-36/37/38-42
101-68-8
Xn
20-36/37/38-42
2844-92-0
E,T+,N
1-26/27/28-33-
CAS number
Symbol
Risk-phrases
88-85-7
1420-07-1
Page 87 of 236
DIPROPYLAMINE
(1/2-)16-26-36/37/39-45
DIPROPYLENETRIAMINE
(1/2-)26-28-36/37/39-45
DI-n-PROPYL ETHER
(2-)9-16-33
DIPROPYL KETONE
(2-)23
DIQUAT
(1/2-)22-36/37/39-45
DIQUAT, SALTS
(1/2-)22-36/37/39-45 Note A
DISODIUM N-CARBOXYMETHYL-N-(2(2-)26-39
(2-HYDROXYETHOXY)ETHYL)GLYCINATE
DISODIUM ETHYLENEBISDITHIOCARBAMATE
(2-)8-24/25-46
DISODIUM S,S'-HEXANE-1,6-DIYLDI(THIOSULPHATE)
(2-)22-24-37-61
DIHYDRATE
DISODIUM METASILICATE
(1/2-)13-24/25-36/37/39-45
DISODIUM 7-OXABICYCLO(2,2,1)HEPTANE-2,3(1/2-)36/37/39-45
DICARBOXYLATE
DISULFOTON
(1/2-)28-36/37-45-60-61
DISULPHUR DICHLORIDE
(1/2-)26-45
DITALIMFOS
(2-)36/37
DITHALLIUM SULPHATE
(1/2-)13-36/37-45
DITHIANON
(2-)24
DIURON
(2-)22-37
DIXANTHOGEN
(2-)24
DNOC
40-44
(1/2-)36/37-45
DNOC, AMMONIUM SALT
(1/2-)13-28-45
DNOC, POTASSIUM SALT
(1/2-)13-45
DNOC, SODIUM SALT
(1/2-)13-45
DODECYLQUANIDIUM ACETATE
(2-)26
DODECYL 3,4,5-TRIHYDROXYBENZOATE
(2-)24-37
DODEMORPH
(2-)26
DODINE
(2-)26
DRAZOXOLON
(1/2-)22-24-36/37-45
EDIFENPHOS
(1/2-)28-36/37-45
142-84-7
56-18-8
T+,C
22-24-26-35-43
111-43-3
11-19
123-19-3
10
2764-72-9
24/25-36/37/38
24/25-36/37/38
92511-22-3
Xi
41
142-59-6
Xn
22-37-43
Xi
43-52/53
6834-92-0
34-37
129-67-9
21-25-36/37/38
298-04-4
T+,N
27/28-50/53
10025-67-9
14-34-37
5131-24-8
Xi
38-43
7446-18-6
T+
28-38-48/25
3347-22-6
Xn
22
330-54-1
Xn
48/22
502-55-6
Xn
22
534-52-1
T+
27/28-33-36-
2980-64-5
T+
26/27/28-33
5787-96-2
23/24/25-33
2312-76-7
23/24/25-33
2439-10-3
Xn
22-36/38
1166-52-5
Xi
43
1593-77-7
Xi
36/37/38
2439-10-3
Xn
22-36/38
5707-69-7
25
17109-49-8
23/24/25
Page 88 of 236
ENDOSULFAN
(1/2-)28-36/37-45-60-61
ENDOTHAL
(1/2-)36/37/39-45
ENDOTHAL-SODIUM
(1/2-)36/37/39-45
ENDOTHION
(1/2-)36/37-45
ENDRIN
(1/2-)22-36/37-45-60-61
EPHEDRINE
(2-)22-25
EPHEDRINE, SALTS
(2-)22-25 Note A
EPICHLOROHYDRIN
23/24/25-34-43
53-45 Note E
EPN
(1/2-)22-36/37-45-60-61
(EPOXYETHYL)BENZENE
53-45 Note E
1,2-EPOXY-4-EPOXYETHYLCYCLOHEXANE
(1/2-)23-24-45
2,3-EPOXY-1,4,5,6,7,8,8-HEPTACHLORO(1/2-)36/37-45-60-61
3a,4,7,7a-TETRAHYDRO-4,7-METHANOINDANE
1,2-EPOXY-3-PHENOXYPROPANE
(2-)24/25
1,2-EPOXYPROPANE
20/21/22-36/37/38 53-45 Note E
2,3-EPOXY-1-PROPANOL
36/37/38-42/43 (1/2-)45
2,3-EPOXYPROPYL ACRYLATE
(1/2-)26-36/37/39-45 Note D
2,3-EPOXYPROPYL-2-ETHYLCYCLOHEXYL ETHER
(2-)26-28-37/39
2,3-EPOXYPROPYL METHACRYLATE
36/38-43
(2-)26-28 Note D
EPOXYRESIN, reaction product:
(2-)28-37/39
BISPHENOL-A(EPICHLOROHYDRIN), average
molecule weight <700
1,2-EPOXY-3-(TOLYLOXY)PROPANE
(2-)26-28 Note C
EPTC
(2-)23
ERBON
(2)
ERIONITE
53-45
ESERIN
(1/2-)25-45
ETHANAL
(2-)16-33-36/37
ETHANE
(2-)9-16-33
ETHANEDIOL
(2)
ETHANE-1,2-DIONE
(2-)26-28 Note B
115-29-7
145-73-3
21-25-36/37/38
129-67-9
21-25-36/37/38
2778-04-3
24/25
72-20-8
T+,N
24-28-50/53
299-42-3
Xn
22
Xn
22
106-89-8
45-10-
2104-64-5
T+,N
27/28-50/53
96-09-03
45-21-36
106-87-6
23/24/25-40
1024-57-3
T,N
25-33-40-50/53
122-60-1
Xn
21-43
75-56-9
F+,T
45-12-
556-52-5
21/22-23-
106-90-1
23/24/25-34-43
130014-35-6 Xi
36/38-43
106-91-2
Xn
20/21/22-
25068-38-6
Xi
36/38-43
26447-14-3
Xi
38
759-94-4
Xn
22
136-25-4
Xn
22
12510-42-8
45
57-47-6
T+
26/28
75-07-0
F+,Xn
12-36/37-40
74-84-0
F+
12
107-21-1
Xn
22
107-22-2
Xi
36/38
Page 89 of 236
ETHANETHIOL
(2-)16-25
Page No.
18/11/96
75-08-1
18
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
ETHANOL
(2-)7-16
ETHANOLAMINE
(2)
ETHIOFENCARB
(2)
ETHION
(1/2-)25-36/37-45
ETHIRIMOL
(2-)36/37
ETHOATE-METHYL
(2-)36/37
ETHOPROPHOS
(1/2-)36/37/39-45
ETHOXIDES, ALKALI
(1/2-)8-16-26-43-45 Note A
2-ETHOXYANILINE
(1/2-)28-36/37-45 Note C
4-ETHOXYANILINE
(1/2-)28-36/37-45 Note C
N-ETHOXYCARBONYL-N-METHYLCARBAMOYLMETHYL
(1/2-)36/37-45-60-61
O,O-DIETHYL PHOSPHORODITHIOATE
6-ETHOXY-1,2-DIHYDRO-2,2,4-TRIMETHYLQUINOLINE
(2-)24
2-ETHOXYETHANOL
20/21/22
53-45 Note E
2-ETHOXYETHYL ACETATE
53-45 Note E
ETHOXYQUIN
(2-)24
ETHYL ACETATE
(2-)16-23-29-33
ETHYL ACRYLATE
36/37/38-43 (2-)9-16-33-36/37 Note D
ETHYL ALCOHOL
(2-)7-16
ETHYLAMINE
(2-)16-26-29
2-ETHYLAMINO-4-ISOPROPYLAMINO-6-METHYLTHIO(2-)36
1,3,5-TRIAZINE
N-ETHYLANILINE
(1/2-)28-37-45
ETHYLBENZENE
(2-)16-24/25-29
ETHYL BROMIDE
(2-)28
ETHYL BROMOACETATE
64-17-5
11
141-43-5
Xn
20-36/37/38
29973-13-5
Xn
22
563-12-2
21-25
23947-60-6
Xn
21
116-01-8
Xn
21/22
13194-48-4
T+
25-27
F,C
11-14-34
94-70-2
23/24/25-33
156-43-4
23/24/25-33
2595-54-2
T,N
24/25-50/53
91-53-2
Xn
22
110-80-5
60-61-10-
111-15-9
60-61-20/21/22
91-53-2
Xn
22
141-78-6
11
140-88-5
F,Xn
11-20/21/22-
64-17-5
11
75-04-7
F+,Xi
12-36/37
834-12-8
Xn
22
103-69-5
23/24/25-33
100-41-4
F,Xn
11-20
74-96-4
Xn
20/21/22
105-36-2
T+
26/27/28
Page 90 of 236
97-95-0
Xn
21/22
97-95-0
Xn
21/22
51-79-6
45
116-01-8
Xn
21/22
75-00-3
F+,Xn
12-40-52/53
105-39-5
T,N
23/24/25-50
541-41-3
F,T+
11-22-26-34
130014-35-6 Xi
36/38-43
4234-79-1
22-24
2597-03-7
Xn
21/22
598-56-1
F+,C
12-20/22-34
924-99-2
Xi
43
759-94-4
Xn
22
74-85-1
F+
12
2514-53-6
Xi
38
107-07-3
T+
26/27/28
107-15-3
10-21/22-34-
C,N
22-34-50/53
106-93-4
T,N
45-23/24/25-
107-06-2
F,T
51/53
45-11-22-
97-90-5
Xi
36/37
628-96-6
E,T+
2-26/27/28-33
1680-21-3
Xi
36/38-43
107-21-1
Xn
22
97-90-5
Xi
36/37
110-71-4
Xn
10-19-20
Page 91 of 236
628-96-6
111-76-2
Xn
20/21/22-37
110-80-5
60-61-10-
109-59-1
Xn
20/21-36
109-86-4
60-61-10-
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
2-ETHYLHEXYL 3,5-BIS(1,1-DIMETHYLETHYL)53-45
4-HYDROXYPHENYL METHYL THIOACETATE
ETHYLENEIMINE
26/27/28-3453-45-61 Note D, E
80387-97-9
61-43
151-56-4
F,T+,N
45-46-11-
ETHYLENE OXIDE
36/37/38
53-45 Note E
ETHYLENE THIOUREA
53-45 Note E
ETHYL FORMATE
(2-)9-16-33
ETHYL GLYCOL
20/21/22
53-45 Note E
ETHYLGLYCOL ACETATE
53-45 Note E
2-ETHYLHEXANE-1,3-DIOL
(2-)26
2-ETHYLHEXANOIC ACID
(2-)36/37
2-ETHYLHEXYL ACRYLATE
(2-)24-37 Note D
O-ETHYLHYDROXYLAMINE
36-43(1/2-)16-26-36/37/39-38-
75-21-8
F+,T
51/53
45-46-12-23-
96-45-7
61-22
109-94-4
11
110-80-5
60-61-10-
111-15-9
60-61-20/21/22
94-96-2
Xi
36
149-57-5
Xn
63
103-11-7
Xi
37/38-43
624-86-2
F,T,N
11-23/24/25-
45-61
ETHYLIDENE DICHLORIDE
52/53
(2-)16-23-61
ETHYL LACTATE
(2-)23
ETHYL MERCAPTAN
(2-)16-25
ETHYL METHACRYLATE
(2-)9-16-29-33 Note D
ETHYL METHYL ETHER
(2-)9-16-33
ETHYL METHYL KETONE
(2-)9-16-25-33
ETHYL METHYL KETOXIME
(2-)23-24
ETHYL NITRATE
48/20-50
75-34-3
F,Xn
11-22-36/37-
97-64-3
10
75-08-1
F,Xn
11-20
97-63-2
F,Xi
11-36/37/38-43
540-67-0
F+
12
78-93-3
F,Xi
11-36/37
96-29-7
Xi
36-43
625-58-1
Page 92 of 236
109-95-5
E,Xn
2-20/21/22
2104-64-5
T+,N
27/28-50/53
Xi
10-41
944-22-9
T+,N
27/28-50/53
105-37-3
11
78-10-4
Xn
10-20-36/37
2703-37-9
T+
26/27/28
301-12-2
T,N
24/25-50
5827-05-4
T+
25-27
17040-19-6
21-25
867-27-6
25
640-15-3
21-25
919-86-8
T,N
24/25-51/53
327-98-0
T+,N
24-28-50/53
74-86-2
F+
5-6-12
38260-54-7
Xn
22
97-56-3
45-43
Xi, N
38-51/53
140-56-7
21-25
22224-92-6
T+
24-28
14255-88-0
Xn
21/22
13356-0806
Xn
21-36/38
299-84-3
Xn
21/22
Page 93 of 236
FENITROTHION
(2-)60-61
FENOPROP
(2-)37
FENOPROP, SALTS
(2-)13 Note A
FENSON
(2-)24-26
FENSULFOTHION
(1/2-)23-28-36/37-45-60-61
FENTHION
(1/2-)36/37-45-60-61
Page No.
20
18/11/96
122-14-5
93-72-1
22-38
Xn
20/21/22
80-38-6
Xn
22-36
115-90-2
T+,N
27/28-50/53
55-38-9
T,N
21-25-50/53
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
FENTIN ACETATE
36/38-43-50/53 (1/2-)36/37-45-60-61
FENTIN HYDROXIDE
36/38-50/53
(1/2-)36/37-45-60-61
FENURON-TCA
(2)
FERBAM
(2)
FICIN
(2-)22-24-26-36/37
FLUENETIL
(1/2-)28-36/37-45
FLUORINE
(1/2-)9-26-36/37/39-45
2-FLUOROACETAMIDE
(1/2-)36/37-45
FLUOROACETATES, soluble
(1/2-)20-22-26-45 Note A
FLUOROACETIC ACID
(1/2-)20-22-26-45
FLUOROBORIC ACID, conc.>25%
(1/2-)26-27-45 Note B
N-(FLUORODICHLOROMETHYLTHIO)PHTHALIMIDE
(2-)28
2-FLUOROETHYL BIPHENYL-4-YLACETATE
(1/2-)28-36/37-45
FLUOROSILICATES, with the exception of those
(2-)13-24/25 Note A
specified elsewhere in this Annex
FLUOROSILICATES, ALKALINE (Na, K, NH4)
(1/2-)26-45 Note A
FLUOROSILICIC ACID
(1/2-)26-27-45 Note B
FLUOROSULPHONIC ACID
(1/2-)26-45
FLUOROSULPHURIC ACID
(1/2-)26-45
2-FLUORO-5-TRIFLUOROMETHYLPYRIDINE
(2-)24-37-61
900-95-8
T+,N
24/25-26-
76-87-9
T+,N
24/25-26-
4482-55-7
Xi
38
14484-64-1
Xi
36/37/38
9001-33-6
Xn
36/37/38-42
4301-50-2
T+
27/28
7782-41-4
T+,C
7-26-35
640-19-7
T+
24-28
T+
28
144-49-0
T+
28
16872-11-0
34
719-96-0
Xi
38
4301-50-2
T+
27/28
Xn
22
23/24/25
16961-83-4
34
7789-21-1
20-35
7789-21-1
20-35
69045-82-5
Xi
10-43-52/53
Page 94 of 236
FOLPET
(2-)36/37
FONOFOS
(1/2-)28-36/37-45-60-61
FORMALDEHYDE, reaction products with
(2-)24-37
BUTYLPHENOL
FORMALDEHYDE solution, 1%conc.<5%
(1/2-)23-37 Note B, D
FORMALDEHYDE solution, 5%conc.<25%
36/37/38-40-43 (1/2-)26-36/37-51 Note B, D
FORMALDEHYDE solution, conc.>25%
40-43
(1/2-)26-36/37/39-45-51
Note B, D
FORMETANATE
(1/2-)22-36/37-45
FORMETANATE HYDROCHLORIDE
(1/2-)22-36/37-45
FORMIC ACID, conc.>90%
(1/2-)23-26-45 Note B
FORMIC ACID, 10%<CONC.40%
(1/2-)7/9-26-45 Note B
HYDROCARBONS
53-45
C26-C55 aromatic rich
HYDROCHLORIC ACID, 10%conc.<25%
(1/2-)26 Note B
HYDROCHLORIC ACID, conc.25%
(1/2-)26-45 Note B
HYDROCYANIC ACID
(1/2-)7/9-16-36/37-38-45
HYDROFLUORIC ACID
(1/2-)7/9-26-36/37-45 Note B
Page No.
22
18/11/96
133-07-3
944-22-9
T+,N
27/28-50/53
91673-30-2
Xi
43
50-00-0
Xn
40-43
50-00-0
Xn
20/21/22-
50-00-0
23/24/25-34-
22259-30-9
T+
28
23422-53-9
T+
28
64-18-6
35
34-37
T
45
Xi
36/37/38
34-37
74-90-8
F+,T+
12-26
7664-39-3
T+,C
26/27/28-35
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
HYDROGEN
(2-)9-16-33
HYDROGEN BROMIDE
(1/2-)7/9-26-45
HYDROGEN CHLORIDE, water solution
(1/2-)26-45 Note B
HYDROGEN CHLORIDE, anhydrous
(1/2-)9-26-36/37/39-45
HYDROGEN CYANIDE
(1/2-)7/9-16-36/37-38-45
HYDROGEN CYANIDE, SALTS with the exception of
(1/2-)7-28-29-45 Note A
complex cyanides as FERRO-, FERRICYANIDES,
MERCURIC OXOCYANIDE
HYDROGEN FLUORIDE
(1/2-)7/9-26-36/37/39-45
HYDROGEN IODIDE anhydrous
(1/2-)9-26-36/37/39-45
1333-74-0
F+
12
10035-10-6
35-37
34-37
7647-01-0
T,C
23-35
74-90-8
F+,T+
12-26
T+
26/27/28-32
32057-09-3
T+,C
26/27/28-35
10034-85-2
35
97722-04-8
Page 95 of 236
7722-84-1
HYDROXYLAMINE HYDROCHLORIDE
48/22-50
(2-)22-24-37-61
HYDROXYLAMINE SULPHATE (1:1)
48/22-50
(2-)22-24-37-61
HYDROXYLAMINE SULPHATE (2:1)
48/22-50
(2-)22-24-37-61
HYDROXYLAMMONIUM CHLORIDE
48/22-50
(2-)22-24-37-61
HYDROXYLAMMONIUM HYDROGENSULPHATE
48/22-50
(2-)22-24-37-61
4-HYDROXY-4-METHYLPENTAN-2-ONE
(2-)7-16-24/25
4-HYDROXY-3-[3-OXO-1-(4-CHLOROPHENYL)BUTYL]
(2-)37
COUMARIN
4-HYDROXY-3-[3-OXO-1-(2-FURYL)BUTYL]COUMARIN
(1/2-)37-45
4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)COUMARIN
53-45 Note E
HYDROXYPROPYL ACRYLATE, mixture of isomers
(1/2-)26-36/37/39-45 Note C, D
HYDROXYPROPYL METHACRYLATE, mixture of
(2-)26-28 Note D
isomers
5-(I-HYDROXY-I-2-PYRIDYLBENZYL)-7(2)
(I-2-PYRIDYLBENZYLIDENE)BICYCLO [2.2.1]
HEPT-5-ENE-2,3-DICARBOXIMIDE
4-HYDROXY-3-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL)
(1/2-)36/37-45
COUMARIN
HYOSCINE
(1/2-)25-45
HYOSCINE, SALTS
(1/2-)25-45 Note A
36/38
Xi
43-52/53
F+,T+,N
12-26-50
34
123-31-9
Xn
20/22
1689-83-4
21-25-63
818-61-1
24-34-43
868-77-9
Xi
36/38-43
3547-33-9
Xi
41
7803-49-8
Xn,C
5-22-37/38-41-
5470-11-1
Xn,N
48/22-50
22-36/38-43-
10046-00-1
Xn,N
22-36/38-43-
10039-54-0
Xn,N
22-36/38-43-
5470-11-1
Xn,N
22-36/38-43-
10046-00-1
Xn,N
22-36/38-43-
123-42-2
F,Xi
11-36
81-82-3
Xn
48/22
117-52-2
25-48/25
81-81-2
61-48/25
25584-83-2
23/24/25-34-43
923-26-2
Xi
36/38
2761-09-3
991-42-4
Xn
22
5836-29-3
T+
27/28-48/24/25
51-34-3
T+
26/27/28
T+
26/27/28
7783-06-4
Page 96 of 236
HYOSCYAMINE
(1/2-)24-45
HYOSCYAMINE, SALTS
(1/2-)24-45 Note A
IMAZALIL
(2)
IMAZALIL SULPHATE
(2-)26
IMIDAZOLIDINE-2-THIONE
53-45 Note E
2-IMIDAZOLINE-2-THIOL
53-45 Note E
2,2'-IMINODIETHANOL
(2-)26
2,2'-IMINODIETHYLAMINE
(1/2-)26-36/37/39-45
1,1'-IMINODIPROPAN-2-OL
(2-)26
3,3'-IMINODI(PROPYLAMINE)
(1/2-)26-28-36/37/39-45
IODINE
(2-)23-25
IODOACETIC ACID
(1/2-)22-36/37/39-45
IODOMETHANE
37/38-40
(1/2-)36/37-38-45
IODOXYBENZENE
(2-)35
3-IODPROPENE
(1/2-)7-26-45
IOXYNIL
(1/2-)36/37-45
IOXYNIL OCTANOATE
(2-)36/37
IPROBENFOS
(2)
ISOBENZAN
(1/2-)28-36/37-45-61
ISOBORNYL THIOCYANOACETATE
(2-)24/25
Page No.
23
18/11/96
101-31-5
26/28
35554-44-0
Xn
22-36
58594-72-2
Xn
22-41
96-45-7
61-22
96-45-7
61-22
111-42-2
Xi
36/38
111-40-0
21/22-34-43
110-97-4
Xi
36
56-18-8
T+,C
22-24-26-35-43
7553-56-2
Xn
20/21
64-69-7
T,C
25-35
74-88-4
21-23/25-
696-33-3
556-56-9
10-34
1689-83-4
21-25-63
3861-47-0
Xn
22-63
26087-47-8
Xn
22
297-78-9
T+,N
27/28-50
115-31-1
Xn
22
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
ISOBUTYL ACRYLATE
(2-)9-24-37 Note D
ISOBUTYL 2-(4-(4-CHLOROPHENOXY)
(2)
PHENOXY)PROPIONATE
ISOBUTYL 3,4-EPOXYBUTYRATE
(2-)24-28-36/37-60-61
4,4'-ISOBUTYLETHYLIDENEDIPHENOL
(2-)26-60-61
ISOBUTYLISOPROPYLDIMETHOXYSILANE
(2-)25-26-36/37
ISOBUTYL METHACRYLATE
106-63-8
Xn
10-20/21-38-43
51337-71-4
Xn
22
100181-71-3 Xi,N
38-43-50/53
6807-17-6
36-50/53
Xi,N
111439-76-0 Xn
10-20-38
97-86-9
10-36/37/38-43
Xi
Page 97 of 236
79-31-2
Xn
21/22
79-30-1
F,C
11-35
4098-71-9
23-36/37/38-
4083-64-1
Xn
14-36/37/38-42
465-73-6
T+,N
26/27/28-50/53
25311-71-1
24/25
119-38-0
T+
27/28
78-78-4
11
78-59-1
Xi
36/37/38
2855-13-2
21/22-34-43-
4098-71-9
23-36/37/38-
78-79-5
F+
12
2631-40-5
Xn
22
78-96-6
34
98-83-9
Xi
10-36/37
109-59-1
Xn
20/21-36
114-26-1
25
108-21-4
11
67-63-0
11
75-31-0
F+,Xi
12-36/37/38
1014-69-3
Xn
21/22
98-82-8
Xi
10-37
25057-89-0
Xn
22-36
105-48-6
10-25-36/37/38
625-55-8
11
80-05-7
Xi
36/37/38-43
87172-89-2
O,Xn
8-22-36
Page 98 of 236
5-ISOPROPYL-3-METHYLPHENYL METHYLCARBAMATE
(1/2-)24-37-45
1-ISOPROPYL-3-METHYLPYRAZOL-5-YL
(1/2-)28-36/37/39-45
DIMETHYLCARBAMATE
S-[2-(ISOPROPYL SULPHINYL)-ETHYL]
(1/2-)13-45
O,O-DIMETHYL PHOSPHOROTHIOATE
ISOPROTURON
(2-)36/37
ISOTHIOATE
(1/2-)28-36/37-45
ISOXATHION
(1/2-)28-36/37-45
KELEVAN
(1/2-)36/37-45
LEAD ACETATE
48/22
53-45 Note E
LEAD ALKYLS
26/27/28-33-50/53 53-45-60-61 Note A, E
LEAD AZIDE
33
53-45 Note E
LEAD CHROMATE
50/53
53-45-60-61
LEAD COMPOUNDS with the exception of those
53-45 Note A, E
specified elsewhere in this Annex
LEAD DIACETATE
53-45 Note E
LEAD HEXAFLUOROSILICATE
53-45 Note E
LEAD(II) METHANESULPHONATE
33-3853-45-57-61 Note E
2631-37-0
119-38-0
T+
27/28
2635-50-9
23/24/25
34123-59-6
Xn
22-40
36614-38-7
24/25
18854-01-8
24/25
4234-79-1
22-24
1335-32-6
61-62-33-40-
T+,N
61-62-
13424-46-9
E,T
61-62-3-20/22-
7758-97-6
T,N
61-62-33-40-
61-62-20/22-33
301-04-2
61-62-33-48/22
25808-74-6
61-62-20/22-33
17570-76-2
T,N
61-62-20/22-
LEADSTYPHNATE
33
53-45 Note E
LEAD 2,4,6-TRINITRORESORCINOXIDE
33
53-45 Note E
LEPTOPHOS
50/53
(1/2-)25-36/37/39-45-60-61
LINDANE
36/38-50/53
(1/2-)13-45-60-61
LINURON
(2-)36/37
LITHIUM
(1/2-)8-43-45
Page No.
24
18/11/96
15245-44-0
E,T
41-48/20/22-58
61-62-3-20/22-
15245-44-0
E,T
61-62-3-20/22-
21609-90-5
T,N
21-25-39/25-
58-89-9
T,N
23/24/25-
330-55-2
Xn
40
7439-93-2
F,C
14/15-34
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
F,C
14-17-34
12057-74-8
F,T+
15/29-28
7439-95-4
15-17
Page 99 of 236
11-15
Xn
22
Xn
22-36/37/38
Xn
22-36/37/38-42
23/24/25
Xn
20/22
Xn
48/20/22
Xn
22-38-41
Xn
20/21/22
Xn
22
Xn
22
T,N
24/25-50/53
Xn
22-38-41
Xn
20/21/22
21-25
Xn
22-52/53
Xi
10-38
O,C
7-20-34
O,C
7-20-34
T+,N
27/28-51/53
25
T+
28-34-48/24/25
E,T
3-23/24/25-33
E,T
3-23/24/25-33
23-33
T+
26/27/28-33
T+
28-34-48/24/25
T+
26/27/28-33
T+
26/27/28-33
108-67-8
Xi
10-37
141-79-7
Xn
10-20/21/22
108-62-3
Xn
10-22
121-47-1
Xn
20/21/22
Xi
36/37/38
79-41-4
34
126-98-7
F,T
11-23/24/25-43
563-47-3
F,C,N
11-20/22-34-
10265-92-6
T+,N
24-28-36-50
74-82-8
F+
12
75-75-2
34
74-93-1
F+,Xn
12-20
67-56-1
F,T
11-23/25
20354-26-1
Xn
21/22-36/38
100-97-0
F,Xn
11-42/43
950-37-8
T+,N
21-28-50/53
2032-65-7
25
16752-77-5
T+
28
F,C
11-14-34
90-04-0
T+,N
45-26/27/28-
104-94-9
T+,N
26/27/28-33-50
4435-53-4
Xi
36
7786-34-7
T+
27/28
109-86-4
60-61-10-
110-49-6
60-61-20/21/22
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
2-METHOXYETHYLCARBAMOYLMETHYL
(2-)24-36
O,O-DIMETHYL PHOSPHORODITHIOATE
2-METHOXYETHYLMERCURY CHLORIDE
(1/2-)36/37/39-45
2-METHOXY-1-METHYLETHYL ACETATE
(2-)25
4-METHOXY-4-METHYLPENTAN-2-ONE
(2-)23
4-METHOXY-2-NITROANILINE
52/53
(1/2-)28-36/37-45-61
1-METHOXY-2-PROPANOL
(2-)24
S-(5-METHOXY-4-OXOPYRAN-2-YLMETHYL) DIMETHYL
(1/2-)36/37-45
PHOSPHOROTHIOATE
METHYL ACETATE
(2-)16-23-29-33
METHYL ACETOACETATE
(2-)26
METHYL ACRYLAMIDOMETHOXYACETATE
53-45 Note E
(containing 0.1% ACRYLAMIDE)
METHYL ACRYLATE
36/37/38
(2-)9-16-33 Note D
METHYL ALCOHOL
(1/2-)7-16-24-45
METHYLAMINE, mono-, di-, tri
(2-)16-26-39
METHYLAMINE, mono-, solution
(1/2-)3-16-26-29-36/37/39-45
919-76-6
Xn
22
123-88-6
25-34-48/25
108-65-6
Xi
10-36
107-70-0
10
96-96-8
T+
26/27/28-33-
107-98-2
10
2778-04-3
24/25
79-20-9
11
105-45-3
Xi
36
77402-03-0
45-46-22-36
96-33-3
F,Xn
11-20/22-
67-56-1
F,T
11-23/25
F+,Xn
12-20-37/38-41
74-89-5
F+,C
12-20/22-34
Note B
METHYLAMINE, di-, solution
(1/2-)3-16-26-29-36/37/39-45
124-40-3
F+,C
12-20/22-34
Note B
METHYLAMINE, tri-, solution
(1/2-)3-16-26-29-36/37/39-45
75-50-3
F+,C
12-20/22-34
109-83-1
34
109-83-1
34
100-61-8
T,N
23/24/25-33-
75-55-8
F,T+
45-11-
592-62-1
45-61
592-62-1
45-61
Note B
2-METHYLAMINOETHANOL
(1/2-)23-26-36-45
N-METHYL-2-AMINOETHANOL
(1/2-)23-26-36-45
N-METHYLANILINE
50/53
(1/2-)28-36/37-45-60-61
METHYLAZIRIDINE
26/27/28-41
53-45 Note E
METHYL-O,N,N-AZOXYMETHYL ACETATE
53-45
METHYL AZOXY METHYL ACETATE
53-45
DL-I-METHYLBENZYLAMINE
(1/2-)26-28-36/37/39-45
METHYL BROMIDE
50/53-59
(1/2-)15-27-36/37/39-38-
618-36-0
74-83-9
45-59-61
2-METHYLBUTA-1,3-DIENE
78-79-5
F+
(2-)9-16-29-33 Note D
2-METHYLBUTAN-2-OL
75-85-4
F,Xn
(2-)9-16-24/25
3-METHYLBUTAN-2-ONE
563-80-4
F
(2-)9-16-33
2-(1-METHYLBUTYL)-4,6-DINITROPHENOL
4097-36-3
T
(1/2-)13-45
METHYL n-BUTYL KETONE
591-78-6
F,T
(1/2-)9-16-29-45-51
METHYLCARBOPHENOTHIONE
953-17-3
T
(1/2-)28-36/37-45
METHYL CHLORIDE
74-87-3
F+,Xn
(2-)9-16-33
METHYL CHLOROACETATE
96-34-4
T
37/38-41
(1/2-)26-37/39-45
METHYL 2-CHLORO-3-(4-CHLOROPHENYL) PROPIONATE 14437-17-3 Xn
(2-)36/37
METHYL CHLOROFORM
71-55-6
Xn,N
(2-)24/25-59-61 Note F
METHYL CHLOROFORMATE
79-22-1
F,T
(1/2-)9-16-33-45
METHYLCYCLOHEXANE
108-87-2
F
(2-)9-16-33
2-METHYLCYCLOHEXANOL
583-59-5
Xn
(2-)24/25
2-METHYLCYCLOHEXANONE
583-60-8
Xn
(2-)25
METHYL 3,4-DICHLOROPHENYLCARBANILATE
1918-18-9
Xn
(2)
N-METHYLDIETHANOLAMINE
105-59-9
Xi
(2-)24
METHYL I-((4,6-DIMETHOXYPYRIMIDIN-2-YL)
83055-99-6 Xi,N
(2-)24-37-61
UREIDOSULPHONYL)-o-TOLUATE
6-METHYL-1,3-DITHIOLO(4,5-b)QUINOXALIN-2-ONE 2439-01-2
Xi
(2-)24-37
4,4'-METHYLENEBIS(2-CHLOROANILINE)
101-14-4
T,N
53-45-60-61 Note E
4,4'-METHYLENEBIS(2-CHLOROANILINE), SALTS
T,N
53-45-60-61 Note A, E
3,3'-METHYLENE BIS(4-HYDROXYCOUMARIN)
66-76-2
T
(1/2-)37-45
1,1'-[METHYLENEBIS(4,1-PHENYLENE)]DIPYRROLEXi,N
(2-)24-37-60-61
2,5-DIONE and 1-(4-(4-)5-OXO-2H-2-FURYLIDENEAMINO)BENZYL)
PHENYL)PYRROLE-2,5-DIONE
2,2'-METHYLENE BIS-(3,4,6-TRICHLOROPHENOL)
70-30-4
T,N
(1/2-)20-37-45-60-61
METHYLENE CHLORIDE
75-09-2
Xn
(2-)23-24/25-36/37
4,4'-METHYLENEDIANILINE
101-77-9
T,N
4353-45-61 Note E
23-36/37/38-
12
11-20
11
23/24/25
11-48/23
24/25
12-40-48/20
10-23/2521/22
20-59
11-23-36/37/38
11
20
10-20
22
36
43-51/53
36-43
45-22-50/53
45-22-50/53
22-48/25
43-50/53
24/25-50/53
40
45-20/21/22-
METHYLENE DIBROMIDE
(2-)24-61
4,4'-METHYLENEDI(CYCLOHEXYL ISOCYANATE)
42/43
(1/2-)26-28-38-45
METHYLENE DITHIOCYANATE
(2-)24-37-61
Page No.
26
18/11/96
74-95-3
5124-30-1
23-36/37/38-
6317-18-6
Xi,N
43-50
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
4,4'-METHYLENEDI-o-TOLUIDINE
53-45-60-61 Note E
N-METHYL-2-ETHANOLAMINE
(1/2-)23-26-36-45
METHYL ETHYL KETONE
(2-)9-16-25-33
METHYL FORMATE
(2-)9-16-33
METHYLGLYCOL ACETATE
53-45 Note E
5-METHYLHEPTAN-3-ONE
(2-)23
5-METHYLHEXAN-2-ONE
(2-)23
1-METHYLIMIDAZOLE
(1/2-)26-36-45
2,2'-(METHYLIMINO)DIETHANOL
(2-)24
METHYL IODIDE
37/38-40
(1/2-)36/37-38-45
METHYL ISOAMYL KETONE
(2-)23
METHYL ISOBUTYL CARBINOL
(2-)24/25
METHYL ISOBUTYL KETONE
(2-)9-16-23-33
METHYL ISOCYANATE
36/37/38
(1/2-)9-30-43-45
METHYL ISOPROPYL KETONE
(2-)9-16-33
METHYL ISOTHIOCYANATE
(1/2-)36/37-38-45
METHYL LACTATE
(2-)23
METHYL MERCAPTAN
(2-)16-25
METHYL METHACRYLATE
(2-)9-16-29-33 Note D
exo-(+/-)-1-METHYL-2-(2-METHYLBENZYLOXY)(2-)22-61
4-ISOPROPYL-7-OXABICYCLO(2.2.1)HEPTANE
2-METHYL-1-(4-METHYLTHIOPHENYL)(2-)22-61
2-MORPHOLINOPROPAN-1-ONE
838-88-0
T,N
45-22-43-50/53
109-83-1
34
78-93-3
F,Xi
11-36/37
107-31-3
F+
12
110-49-6
60-61-20/21/22
541-85-5
Xi
10-36/37
110-12-3
10
616-47-7
21/22-34
105-59-9
Xi
36
74-88-4
21-23/25-
110-12-3
10
108-11-2
Xi
10-37
108-10-1
11
624-83-9
F+,T
12-23/24/25-
563-80-4
11
556-61-6
23/25-34-43
547-64-8
10
74-93-1
F+,Xn
12-20
80-62-6
F,Xi
11-36/37/38-43
89368-00-3
Xn,N
20-51/53
71868-10-5
Xn,N
22-51/53
METHYL 2-(2-NITROBENZYLIDENE)ACETOACETATE
39562-27-1
(2-)24-37-61
METHYL 2-OCTYL-4,6-DINITROPHENYL CARBONATE
63919-26-6
(2)
and METHYL 4-OCTYL-2,6-DINITROPHENYL CARBONATE
1-METHYL-3-NITRO-1-NITROSOGUANIDINE
70-25-7
51/53
53-45-61 Note E
METHYLOXIRANE
75-56-9
20/21/22-36/37/38 53-45 Note E
2-METHYLPENTANE-2,4-DIOL
107-41-5
(2)
4-METHYLPENTAN-2-OL
108-11-2
(2-)24/25
4-METHYLPENTAN-2-ONE
108-10-1
(2-)9-16-23-33
4-METHYLPENT-3-EN-2-ONE
141-79-7
(2-)25
3-(3-METHYLPENT-3-YL)ISOXAZOL-5-YLAMINE
82560-06-3
(1/2-)22-26-36/37/39-45-61
2-METHYL-1-PENTYLPYRIDINIUM BROMIDE
(2-)36/37-61
METHYL PHENOL, all isomers
(1/2-)36/37/39-45 Note C
2-METHYL-m-PHENYLENEDIAMINE
823-40-5
50/53
(2-)24-36/37-60-61
4-METHYL-m-PHENYLENEDIAMINE
95-80-7
43-50/53
53-45-60-61 Note E
2-METHYL-p-PHENYLENEDIAMINE
95-70-5
50/53
(1/2-)24-37-45-60-61
2-METHYL-p-PHENYLENEDIAMINE SULPHATE
615-50-9
50/53
(1/2-)24-37-45-60-61
4-METHYL-m-PHENYLENEDIAMINE SULPHATE
65321-67-7
43-50/53
53-45-60-61 Note E
S-(1-METHYL-1-PHENYLETHYL) PIPERIDINE-161432-55-1
(2-)61
CARBOTHIOATE
2-METHYL-4-PHENYLPENTANOL
92585-24-5
(2-)24-37-61
2-METHYLPROPAN-2-OL
75-65-0
(2-)9-16
2-METHYL-2-PROPENE NITRILE
126-98-7
(1/2-)9-16-18-29-45 Note D
2-METHYLPROPENOIC ACID
79-41-4
(1/2-)15-26-45 Note D
METHYL PROPIONATE
554-12-1
(2-)16-23-29-33
2-METHYLPYRIDINE
109-06-8
36/37
(2-)26-36
4-METHYLPYRIDINE
108-89-4
36/37/38
(1/2-)26-36-45
N-METHYL-2-PYRROLIDONE
872-50-4
(2-)41
METHYL 3-SULPHAMOYL-2-THENOATE
(2-)24-37
I-METHYLSTYRENE
98-83-9
(2)
o-METHYLSTYRENE
611-15-4
(2-)24
METHYL-2,3,5,6-TETRACHLORO-4-PYRIDYLSULPHONE 13108-52-6
22
T,N
45-20-36/38-
F+,T
45-12-
Xi
36/38
Xi
10-37
11
Xn
10-20/21/22
23/25-41-52/53
Xn
21/22-52/53
24/25-34
Xn,N
21/22-40-43-
T,N
45-21-25-36-
T,N
20/21-25-43-
T,N
20/21-25-43-
T,N
45-21-25-36-
Xn,N
22-51/53
Xi,N
43-51/53
F,Xn
11-20
F,T
11-23/24/25-43
34
11
Xn
10-20/21/22-
10-20/22-24-
Xi
36/38
Xi
43
Xi
10-36/37
Xn
20
Xn
21/22-36-43
Xi,N
41-43-51/53
479-45-8
E,T
2-23/24/25-33
116-06-3
T+
27/28
2032-65-7
25
696-44-6
23/24/25-33-
611-21-2
23/24/25-33-
623-09-5
23/24/25-33-
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
5-METHYL-1,2,4-TRIAZOLO(3,4-b)BENZO(2)
1,3-THIAZOLE
METHYLTRICHLOROSILANE
(2-)26-39
1-METHYLTRIMETHYLENE DIACRYLATE
(1/2-)26-36/37/39-45 Note D
METHYL VINYL ETHER
(2-)9-16-33 Note D
METAM-SODIUM
(2-)26-36/37/39
METOLCARB
(2)
METRIBUZIN
(2)
MEVINPHOS
(1/2-)23-28-36/37-45
MEXACARBATE
(1/2-)36/37-45
MIBK
(2-)9-16-23-33
MIPAFOX
(1/2-)13-45
MOLINATE
(2-)24
MOLYBDEMUM TRIOXIDE
(2-)22-25
MONOCHLOROANILINE
50/53
(1/2-)28-36/37-45-60-61 Note C
MONOCHLOROBENZENE
(2-)24/25-61
MONOCROTOPHOS
(1/2-)23-36/37-45-60-61
MONOLINURON
41814-78-2
Xn
22
75-79-6
F,Xi
11-14-36/37/38
19485-03-1
21-34-43
107-25-5
F+
12
137-42-8
Xn
21/22-31-41
1129-41-5
Xn
22
21087-64-9
Xn
22
7786-34-7
T+
27/28
315-18-4
T+
21-28
108-10-1
11
371-86-8
T+
39/26/27/28
2212-67-1
Xn
22
1313-27-5
Xn
36/37-48/20/22
T,N
23/24/25-33-
108-90-7
Xn,N
10-20-51/53
6923-22-4
T+,N
24-28-50/53
1746-81-2
Xn
22
2532-43-6
23/24/25
107-98-2
10
150-68-5
Xn
22-40
Xn
22-36/37/38
Xn
22-36/37/38
110-91-8
10-20/21/22-34
15159-40-7
Xn
14-36/37-40
144-41-2
T,N
23/24/25-50/53
142-59-6
Xn
22-37-43
300-76-5
Xn
21/22-36/38
90-15-3
Xn
21/22-37/38-41
135-19-3
Xn
20/22
135-19-3
Xn
20/22
134-32-7
Xn,N
22-51/53
91-59-8
T,N
45-22-51/53
T,N
45-22-51/53
134-32-7
Xn,N
22-51/53
91-59-8
T,N
45-22-51/53
2243-62-1
Xn,N
40-50/53
3173-72-6
Xn
20-36/37/38-42
1786-03-4
25
1786-03-4
25
63-25-2
Xn
22
86-88-4
T+
28-40
86-88-4
T+
28-40
463-82-1
F+
12
2223-82-7
24-36/38-43
7440-02-0
Xn
40-43
3333-67-3
Xn
22-40-43
NICKEL DIHYDROXIDE
(2-)22-36
NICKEL DIOXIDE
53-45
NICKEL MONOXIDE
53-45
NICKEL SUBSULPHIDE
53-45
NICKEL SULPHATE
(2-)22-36/37
NICKEL SULPHIDE
53-45
NICKEL TETRACARBONYL
53-45 Note E
NICOTINE
(1/2-)36/37-45
NICOTINE, SALTS
(1/2-)13-28-45 Note A
NITRAPYRIN
(2-)24
NITRIC ACID, conc.>20%
(1/2-)23-26-36-45 Note B
NITRIC ACID, 5%conc.<20%
(1/2-)23-26-27 Note B
NITRIC ACID and SULPHURIC ACID,
(1/2-)23-26-30-36-45 Note B
mixture NITRIC ACID conc.>30%
1,1',1"-NITRILOTRIPROPAN-2-OL
(2-)26
5-NITROACENAPHTHENE
53-45
Page No.
28
18/11/96
12054-48-7
12035-36-8
49-43
1313-99-1
49-43
12035-72-2
49-43
7786-81-4
Xn
22-40-42/43
16812-54-7
49-43
13463-39-3
F,T+
61-11-26-40
54-11-5
T+
25-27
T+
26/27/28
1929-82-4
Xn
22
7697-37-2
O,C
8-35
35
51602-38-1
O,C
8-35
122-20-3
Xi
36
602-87-9
45
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
99-09-2 (o) T
23/24/25-33-
96-96-8
T+
26/27/28-33-
98-95-3
T,N
23/24/25-40-
4-NITROBIPHENYL
53-45
NITROCELLULOSE, containing a maximum of 12.6%
(2-)16-33-37/39
NITROGEN
NITROCELLULOSE, containing more than 12,6%
(2-)35
NITROGEN
NITROETHANE
(2-)9-25-41
NITROFEN
53-45
NITROGEN DIOXIDE
92-93-3
51/53-62
45
11
1-3
79-24-3
Xn
10-20/22
1836-75-5
45-61
10102-44-0
T+
26-34
55-63-0
E,T+
3-26/27/28-33
628-96-6
E,T+
2-26/27/28-33
15825-70-4
75-52-5
Xn
5-10-22
581-89-5
45
100-02-7
Xn
20/21/22-33
100-02-7
Xn
20/21/22-33
108-03-2
Xn
10-20/21/22
79-46-9
45-10-20/22
659-49-4
Xn
20/21/22
62-75-9
T+,N
45-25-26-
621-64-7
T,N
45-22-51/53
1116-54-7
45
88-72-2
T,N
23/24/25-33-
99-99-0
T,N
23/24/25-33-
T,N
23/24/25-33-
34
Xn,N
22-36-51/53
991-42-4
Xn
22
2163-79-3
Xn
22
297-78-9
T+,N
27/28-50
57-74-9
Xn,N
21/22-40-50/53
152-16-9
T+
27/28
111-65-9
11
94-96-2
Xi
36
3547-33-9
Xi
41
1034-01-0
Xn
22-43
14-35-37
112-05-0
OMETHOATE
(1/2-)23-36/37-45-61
ORTOPHOSPHORIC ACID, 10%conc.<25%
(2-)25 Note B
ORTOPHOSPHORIC ACID, conc.25%
(1/2-)26-45 Note B
OSMIC ACID
(1/2-)7/9-26-45
OSMIUM TETROXIDE
(1/2-)7/9-26-45
OUABAIN
(1/2-)45
OXADIAZON
60-61
OXALIC ACID
(2-)24/25
OXALIC ACID, SALTS
(2-)24/25 Note A
OXALIC ACID DIETHYLESTER
(2-)23
OXAMYL
(1/2-)36/37-45
OXIRANE
36/37/38
53-45 Note E
OXYCARBOXIN
(2)
OXYDEMETON-METHYL
(1/2-)23-36/37-45-61
2,2'-OXYDIETHYL DIACRYLATE
(1/2-)28-39-45 Note D
OXYDIETHYLENE BIS(CHLOROFORMATE)
(2-)23-26
OXYDISULFOTON
(1/2-)28-36/37-45
OXYGEN
(2-)17
PAPAIN
(2-)22-24-26-36/37
PAPAVERINE
(2-)22
PAPAVERINE, SALTS
(2-)22 Note A
Page No.
29
18/11/96
1113-02-6
Substance
Safety phrases
PARALDEHYDE
(2-)9-16-29-33
PARAQUAT
(1/2-)22-36/37/39-45
PARAQUAT, SALTS
(1/2-)22-36/37/39-45 Note A
PARATHION
(1/2-)28-36/37-45-60-61
PARATHION-METHYL
36/38
7664-38-2
34
20816-12-0
T+
26/27/28-34
20816-12-0
T+
26/27/28-34
630-60-4
23/25-33
19666-30-9
50/53
144-62-7
Xn
21/22
Xn
21/22
95-92-1
Xn
22-36
23135-22-0
T+
21-26/28
75-21-8
F+,T
45-46-12-23-
5259-88-1
Xn
22
301-12-2
T,N
24/25-50
4074-88-8
24-36/38-43
106-75-2
Xn
22-38-41
2497-07-6
T+
24-28
7782-44-7
9001-73-4
Xn
36/37/38-42
58-74-2
Xn
22
Xn
22
CAS number
Symbol
Risk-phrases
123-63-7
11
4685-14-7
24/25-36/37/38
24/25-36/37/38
56-38-2
T+,N
27/28-50/53
298-00-0
T+
24-28
1336-36-3
Xn,N
33-50/53
1114-71-2
Xn
22
40487-42-1
Xn
22
608-93-5
F,Xn,N
11-22-50/53
76-01-7
T,N
40-48/23-51/53
Xn,N
21/22-36/38-
82-68-8
Xi
43
87-86-5
T+,N
24/25-2640-50/53
(1/2-)22-36/37-45-52-60-61
PENTACHLOROPHENOL, SALTS
36/37/38(1/2-)2236/37-45-52-60-61 Note A
PENTAERYTHRITOL TETRA-ACRYLATE
(2-)26-39 Note D
PENTAERYTHRITOL TETRANITRATE
(2-)35
PENTAERYTHRITOL TRIACRYLATE
(2-)39 Note D
PENTAETHYLENEHEXAMINE
(1/2-)26-36/37/39-45-60-61
PENTANE
(2-)9-16-29-33 Note C
1,5-PENTANEDIAL
42/43-50
(1/2-)26-36/37/39-45-61
PENTANE-2,4-DIONE
(2-)21-23-24/25
tert-PENTANOL
(2-)9-16-24/25
PENTAN-3-ONE
(2-)9-16-33
PENTRIT
(2-)35
PENTYL ACETATE
(2-)23 Note C
PENTYL METHYLPHOSPHINATE and
(1/2-)26-36/37/39-45
2-METHYLBUTYL METHYLPHOSPHINATE mixture
PENTYL NITRITE, mixture of isomers
(2-)16-24-46
PENTYL PROPIONATE
(2-)23 Note C
PEPSIN A
(2-)22-24-26-36/37
PERACETIC ACID, conc.10%
35
(1/2-)3/7-14-36/37/39-45
T+,N
24/25-2640-50/53
4986-89-4
Xi
36/38-43
78-11-5
3524-68-3
Xi
36/38-43
4067-16-7
C,N
34-43-50/53
109-66-0
11
111-30-8
T,N
23/25-34-
123-54-6
Xn
10-22
75-85-4
F,Xn
11-20
96-22-0
11
78-11-5
628-63-7
10
87025-52-3
34
463-04-7
F,Xn
11-20/22
110-46-3
624-54-4
10
9001-75-6
Xn
36/37/38-42
79-21-0
O,C
7-10-20/21/22-
Note B, D
7601-90-3
34
127-18-4
Xn,N
40-51/53
52645-53-1
Xn
22
79-21-0
O,C
7-10-20/21/22-
78-11-5
45
45
91995-78-7
66-71-7
25
94-70-2
23/24/25-33
156-43-4
23/24/25-33
2275-14-1
T,N
23/24/25-50/53
108-95-2
24/25-34
122-99-6
Xn
22-36
2597-03-7
Xn
21/22
14255-88-0
Xn
21/22
108-45-2
T,N
23/24/25-43-
95-54-5
T,N
23/24/25-43-
106-50-3
T,N
23/24/25-43-
541-69-5
T,N
23/24/25-43-
624-18-0
T,N
23/24/25-43-
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
1-PHENYLETHYLAMINE
98-84-0
21/22-34
Note B, D
P.E.T.N.
(2-)35
PETROLEUM DISTILLATES,
53-45
light naphthalenic distillate solvent
heavy paraffinic distillate solvent
light paraffinic distillate solvent
heavy naphthalenic distillate solvent
PETROLEUM DISTILLATES,
53-45
light vacuum gas oil solvent
1,10-PHENANTHROLINE
(1/2-)45
o-PHENETIDINE
(1/2-)28-36/37-45 Note C
p-PHENETIDINE
(1/2-)28-36/37-45 Note C
PHENKAPTON
(1/2-)13-45-60-61
PHENOL
(1/2-)28-45
2-PHENOXYETHANOL
(2-)26
PHENTHOATE
(2-)22-36/37
PHENYL 5,6-DICHLORO-2-TRIFLUOROMETHYL(2-)36/37
BENZIMIDAZOLE-1-CARBOXYLATE
m-PHENYLENEDIAMINE
50/53
(1/2-)28-36/37-45-60-61 Note
o-PHENYLENEDIAMINE
50/53
(1/2-)28-36/37-45-60-61 Note
p-PHENYLENEDIAMINE
50/53
(1/2-)28-36/37-45-60-61 Note
m-PHENYLENEDIAMINE DIHYDROCHLORIDE
50/53
(1/2-)28-36/37-45-60-61 Note
p-PHENYLENEDIAMINE DIHYDROCHLORIDE
50/53
(1/2-)28-36/37-45-60-61 Note
Page No.
30
18/11/96
64742-03-6
64742-04-7
64742-05-8
64742-11-6
C
C
C
C
C
122-60-1
Xn
21-43
100-63-0
T,N
23/24/25-36-50
62-38-4
25-34-48/24/25
8003-05-2
25-34-37-44-
96-09-3
45-21-36
90-43-7
Xi
36/38
132-27-4
Xn
22-38-41
92-43-3
Xn
22
298-02-2
T+
27/28
4104-14-7
T+,N
27/28-50/53
2310-17-0
T,N
21-25-50/53
947-02-4
T+
27/28
75-44-5
T+
26-34
732-11-6
Xn
21/22
5826-76-6
Xn
20/21/22
13171-21-6
T+,N
24-28-40-50/53
7664-38-2
34
Xi
36/38
10025-87-3
34-37
10026-13-8
34-37
1314-80-3
F,Xn
11-20/22-29
1314-56-3
35
11-16
1314-85-8
F,Xn
11-22
7789-60-8
14-34-37
7719-12-2
34-37
12185-10-3
F,T+,C
17-26/28-35
10025-87-3
34-37
14816-18-3
Xn
22
85-44-9
Xi
36/37/38
57-47-6
T+
26/28
T+
26/28
109-06-8
Xn
10-20/21/22-
108-89-4
10-20/22-24-
96-91-3
E,Xn
1-20/21/22-
88-89-1
E,T
2-4-23/24/25
E,T
3-23/24/25
T+
26/28
T+
26/28
83-26-1
25-48/25
110-85-0
34-42/43-52/53
140-31-8
21/22-34-43-
110-89-4
F,T
11-23/24-34
24151-93-7
Xn
22
23103-98-2
25
23505-41-1
T,N
21-25-50/53
29232-93-7
Xn
22
83-26-1
25-48/25
1336-36-3
Xn,N
33-50/53
C,N
21/22-34-43-
7440-09-7
F,C
14/15-34
7789-29-9
T,C
25-34
7758-01-2
O,T
45-9-25
3811-04-9
O,Xn
9-20/22
7789-00-6
T,N
49-46-
590-28-3
Xn
22
7778-50-9
T+,N
49-46-21-25-
92-13-7
41-43-50/53
POTASSIUM FLUORIDE
(1/2-)26-45
POTASSIUM mu-FLUORO-BIS(TRIETHYLALUMINIUM)
(1/2-)16-30-36/39-43-45
Page No.
31
18/11/96
7789-23-3
12091-08-6
F,C
11-14/15-20-35
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
POTASSIUM HEKSAFLUOROSILICATE
(1/2-)26-45 Note A
POTASSIUM HYDROGEN DIFLUORIDE
(1/2-)22-26-37-45
POTASSIUM HYDROGENSULPHATE
(1/2-)26-36/37/39-45
POTASSIUM HYDROXIDE
(1/2-)26-37/39-45
POTASSIUM HYDROXIDE SOLUTION, conc.5%
(1/2-)26-27-37/39
POTASSIUM HYDROXIDE SOLUTION, 0.5%conc.<2%
(2-)26
POTASSIUM 2-HYDROXYCARBAZOLE-1-CARBOXYLATE
(2-)22-26-61
POTASSIUM NITRITE
(1/2-)45
POTASSIUM PERCHLORATE
(2-)13-22-27
POTASSIUM PERMANGANATE
(2)
POTASSIUM POLYSULPHIDES
(1/2-)26-45
POTASSIUM SULPHIDE
(1/2-)26-45
PROFENOFOS
(2-)36/37
PROFLURALIN
(2)
PROMECARB
(1/2-)24-37-45
PROPACHLOR
(2-)24-37
PROPANAL
(2-)9-16-29
PROPANE
(2-)9-16-33
1,3-PROPANESULTONE
53-45 Note E
PROPANIL
(2-)22
1-PROPANOL
(2-)7-16 Note C
PROPAN-2-OL
(2-)7-16 Note C
3-PROPANOLIDE
53-45 Note E
PROPARGITE
16871-90-2
23/24/25
7789-29-9
T,C
25-34
7646-93-7
34-37
1310-58-3
35
35
Xi
36/38
96566-70-0
Xn
22-36/37-52/53
7758-09-0
O,T
8-25
7778-74-7
O,Xn
9-22
7722-64-7
O,Xn
8-22
37199-66-9
31-34
1312-73-8
31-34
41198-08-7
Xn
20/21/22
26399-36-0
Xi
36
2631-37-0
25
1918-16-7
Xn
22-36-43
123-38-6
F,Xi
11-36/37/38
74-98-6
F+
12
1120-71-4
45-21/22
709-98-8
Xn
22
71-23-8
11
67-63-0
11
57-57-8
T+
45-26-36/38
2312-35-8
Xn
22-36
107-19-7
10-23/24/25-34
139-40-2
Xn
40
115-07-1
F+
12
2094-99-7
T+,N
26-34-42/43-
31218-83-4
25
57-57-8
T+
45-26-36/38
123-38-6
F,Xi
11-36/37/38
79-09-4
34
79-09-4
Xi
36/37/38
123-62-6
34
79-03-8
F,C
11-14-34
114-26-1
25
109-60-4
11
103-65-1
Xi
10-37
106-94-5
Xn
10-20
1114-71-2
Xn
22
540-54-5
F,Xn
11-20/21/22
109-61-5
10-23-34
115-07-1
F+
12
108-32-7
Xi
36
78-90-0
10-21/22-35
5131-66-8
Xi
36/38
75-55-8
F,T+
45-11-
75-56-9
F+,T
45-12-
503-30-0
F,Xn
11-20/21/22
2122-19-2
Xn
40
110-74-7
11
83-59-0
22-24
2-(PROPYLOXY)ETHANOL
(2-)24/25-36/37
PROPYL PROPIONATE
(2)
PROPYL 3,4,5-TRIHYDROXYBENZOATE
(2-)24-37
PROP-2-YN-1-OL
(1/2-)26-28-36-45
PROTEASES, with exception of those specified
(2-)22-24-26-36/37
elsewhere in this Annex
PROTEINASE, microbial neutral
(2-)22-24-26-36/37
PROTHIOCARB HYDROCHLORIDE
(2)
PROTHOATE
(1/2-)28-36/37-45
PROXAN-SODIUM
(2-)13
Page No.
32
18/11/96
2807-30-9
106-36-5
10
121-79-9
Xn
22-43
107-19-7
10-23/24/25-34
Xn
36/37/38-42
9068-59-1
Xn
36/37/38-42
19622-19-6
Xn
22
2275-18-5
T+
27/28
140-93-2
Xn
22-38
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
PYRAZON
(2-)24-37
PYRAZOPHOS
(2)
PYRAZOXON
(1/2-)13-28-45
PYRETHRIN I
(2-)13
PYRETHRIN II
(2-)13
PYRETHRINS including CINERINS
(2-)13
PYRIDINE
(2-)26-28
PYROCATECHOL
(2-)22-26-37
PYROGALLOL
(2)
PYROMELLITIC DIANHYDRIDE
(2-)25
QUINALPHOS
(1/2-)22-36/37-45
QUINOL
(2-)24/25-39
QUINOMETHIONATE
(2-)24-37
QUINONE
(1/2-)26-28-45
QUINTOZENE
(2-)24-37
RED SQUILL
(1/2-)36/37-45
1698-60-8
Xi
43
13457-18-6
Xn
22
108-34-9
T+
26/27/28
121-21-1
Xn
20/21/22
121-29-9
Xn
20/21/22
Xn
20/21/22
110-86-1
F,Xn
11-20/21/22
120-80-9
Xn
21/22-36/38
87-66-1
Xn
20/21/22
89-32-7
Xi
36/37/38
13593-03-8
21-25
123-31-9
Xn
20/22
2439-01-2
Xi
36-43
106-51-4
23/25-36/37/38
82-68-8
Xi
43
507-60-8
T+
28
RENNIN
(2-)22-24-26-36/37
RESMETHRIN
(2)
RESORCINOL
(2-)26
RESORCINOL DIGLYCIDYL ETHER
(1/2-)23-24-45
ROSIN
(2-)22-23-24-37
ROTENONE
(1/2-)22-24/25-36-45
RYANIA
(2-)36/37
SABADILLA
(2-)36/37/39
SAFROLE
53-45 Note E
SCHRADAN
(1/2-)36/37-38-45
SCILLIROSIDE
(1/2-)36/37-45
SCOPOLAMINE
(1/2-)25-45
SECBUMETON
(2)
SELENIUM
(1/2-)20/21-28-45
SELENIUM COMPOUNDS except CADMIUM
(1/2-)20/21-28-45 Note A
SULPHOSELENIDE
SESAMEX
(2)
SILVER NITRATE
(2-)26-45
SIMAZINE
(2-)36/37
SIMETRYN
(2)
SODIUM
(1/2-)5*-8-43-45
*If appropriate
SODIUM AZIDE
(1/2-)28-45
SODIUM BIFLUORIDE
(1/2-)22-26-37-45
SODIUM 2-BIPHENYLATE
(2-)22-26
SODIUM CARBONATE
(2-)22-26
SODIUM CHLORATE
(2-)13-17-46
SODIUM CHLOROACETATE
(1/2-)22-37-45
SODIUM 3-CHLOROACRYLATE
(2-)36/37
SODIUM-N-CHLORO-p-TOLUENESULPHONAMIDE
(2-)7-15
9001-98-3
10453-86-8
Xn
22
108-46-3
Xn
22-36/38
101-90-6
23/24/25-40-43
8050-09-7
Xn
42/43
83-79-4
25-36/37/38
15662-33-6
Xn
21/22
8051-02-3
Xi
36/37/38
94-59-7
45-22-40
152-16-9
T+
27/28
507-60-8
T+
28
51-34-3
T+
26/27/28
26259-45-0
Xn
22-36
7782-49-2
23/25-33
23/25-33
51-14-9
Xn
22
7761-88-8
34
122-34-9
Xn
40
1014-70-6
Xn
22
7440-23-5
F,C
14/15-34
26628-22-8
T+
28-32
1333-83-1
T,C
25-34
132-27-4
Xn
22-38-41
497-19-8
Xi
36
7775-09-9
O,Xn
9-22
3926-62-3
25-38
4312-97-4
Xn
21/22
127-65-1
Xi
36/37/38
SODIUM CYANATE
(2-)24/25
SODIUM DEHYDRACETATE
(2)
SODIUM DICHLOROISOCYANURATE, DIHYDRATE
(2-)8-26-41
SODIUM DICHROMATE
2653-45-60-61 Note E
50/53
SODIUM DICHROMATE, DIHYDRATE
26-37/3853-45-60-61 Note E
917-61-3
4418-26-2
Xn
22
51580-86-0
Xn
22-31-36/37
10588-01-9
O,T+,N
49-46-8-21-2537/38-41-43-
7789-12-0
T+,N
49-46-21-25-
SODIUM 4-DIMETHYLAMINOBENZENEDIAZOSULPHONATE
(1/2-)36/37-45
SODIUM DITHIONITE
(2-)7/8-26-28-43
SODIUM FLUORIDE
(1/2-)22-36-45
SODIUM FLUOROACETATE
(1/2-)13-22-36/37-45
SODIUM HEXAFLUOROSILICATE
(1/2-)26-45 Note A
SODIUM HYDRIDE
(2-)7/8-24/25-43
SODIUM HYDROGENSULPHATE
(1/2-)26-36/37/39-45
SODIUM HYDROSULPHITE
(2-)7/8-26-28-43
SODIUM HYDROXIDE
(1/2-)26-37/39-45
SODIUM HYDROXIDE SOLUTION, conc.5%
(1/2-)26-27-37/39-45
Page No.
33
18/11/96
140-56-7
41-43-50/53
21-25
7775-14-6
Xn
7-22-31
7681-49-4
25-32-36/38
62-74-8
T+
26/27/28
16893-85-9
23/24/25
7646-69-7
15
7681-38-1
34-37
7775-14-6
Xn
7-22-31
1310-73-2
35
35
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
34
Xi
36/38
7681-52-9
31-34
7681-52-9
Xi
31-36/38
140-93-2
Xn
22-38
137-42-8
Xn
21/22-31-41
7632-00-0
O,T
8-25
127-68-4
Xi
36-43
SODIUM PERCHLORATE
(2-)13-22-27
SODIUM PEROXIDE
(1/2-)8-27-39-45
SODIUM POLYSULPHIDES
(1/2-)26-45
SODIUM SULPHIDE
(1/2-)26-45
SODIUM TRICHLOROACETATE
(2-)24-25
SODIUM 4-2,4,4-TRIMETHYLPENTYLCARBONYLOXY)
43-48/23
(1/2-)22-24-36-45
BENZENESULPHONATE
STANNIC CHLORIDE
(1/2-)7/8-26-45
STRONTIUM CHROMATE
53-45-60-61 Note E
g-STROPHANTIN
(1/2-)45
STROPHANTIN-K
(1/2-)45
STRYCHNINE
(1/2-)36/37-45
STRYCHNINE, SALTS
(1/2-)13-28-45 Note A
STYPHNIC ACID
(2-)35
STYRENE
(2-)23 Note D
STYRENE OXIDE
53-45 Note E
SUBTILISIN
(2-)22-24-26-36/37/39
SUCCINIC ANHYDRIDE
(2-)25
SULFALLATE
53-45 Note E
SULFOTEP
(1/2-)23-28-36/37-45
SULPHAMIC ACID
(2-)26-28
SULPHANILIC ACID
(2-)24-37
SULPHOLANE
(2-)25
SULPHUR DICHLORIDE
(1/2-)26-45
SULPHUR DIOXIDE
(1/2-)9-26-36/37/39-45
SULPHURIC ACID, conc.>15%
(1/2-)26-30-45 Note B
SULPHURIC ACID, 5%<CONC.30% HNO3
SULPHUR TETRACHLORIDE
(1/2-)26-45
SULPHURYL CHLORIDE
(1/2-)26-45
SULPHURYL DIFLUORIDE
(1/2-)23-37/38-45
SWEP
7601-89-0
1313-60-6
O,C
8-35
1344-08-7
31-34
1313-82-2
31-34
650-51-1
Xn
22
22-23-36/37-
7646-78-8
34-37
7789-06-2
T,N
45-22-50/53
630-60-4
23/25-33
11005-63-3
23/25-33
57-24-9
T+
27/28
T+
26/28
82-71-3
E,Xn
2-4-20/21/22
100-42-5
Xn
10-20-36/38
96-09-3
45-21-36
9014-01-1
Xn
36/37/38-41-42
108-30-5
Xi
36/37
95-06-7
45-22
3689-24-5
T+
27/28
5329-14-6
Xi
36/38
121-57-3
Xi
36/38-43
126-33-0
Xn
22
10545-99-0
14-34-37
7446-09-5
23-34
7664-93-9
35
13451-08-6
14-34-37
7791-25-5
14-34-37
2699-79-8
23/25-36/37/38
1918-18-9
Xn
22
93-76-5
Xn
22-36/37/38
Xn
22-36/37/38
50-31-7
Xn
22
117-18-0
Xi
43
107-49-3
T+,N
27/28-50
13071-79-9
T+
27/28
33693-04-8
Xn
22
4067-16-7
C,N
34-43-50/53
118-75-2
Xi,N
36/38-50/53
79-27-6
T+
26-36-52/53
79-34-5
T+
26/27
127-18-4
Xn,N
40-51/53
1897-45-6
Xn
40
56-23-5
T,N
23/24/25-40-
2,3,5,6-TETRACHLORO-4-(METHYLSULPHONYL)
(2-)26/28
PYRIDINE
2,3,4,6-TETRACHLOROPHENOL
(1/2-)26-28-37-45
TETRACHLOROTEREPHTHALONITRILE
(2-)24-37-61
O,O,O',O'-TETRAETHYL DITHIOPYROPHOSPHATE
(1/2-)23-28-36/37-45
Page No.
34
18/11/96
13108-52-6
Xn
52/53-59
21/22-36-43
58-90-2
25-36/38
1897-41-2
Xi
43-53
3689-24-5
T+
27/28
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
TETRAETHYLENEPENTAMINE
51/53
(1/2-)26-36/37/39-45-61
O,O,O',O'-TETRAETHYL S,S'-METHYLENE
(1/2-)25-36/37-45
DI(PHOSPHORODITHIOATE)
TETRAETHYL PYROPHOSPHATE
(1/2-)36/37/39-38-45-61
TETRAETHYL SILICATE
(2)
TETRAHYDRO-3,5-DIMETHYL-1,3,5-THIADIAZINE(2-)15-22-24
2-THIONE
TETRAHYDROFURAN
112-57-2
C,N
21/22-34-43-
563-12-2
21-25
107-49-3
T+,N
27/28-50
78-10-4
Xn
10-20-36/37
533-74-4
Xn
22-36
109-99-9
F,Xi
11-19-36/37
Xi
36/37/38
Xi
36
Xi
36
F,Xn,N
11-20/22-
Xi
19-36/38
O,C
7-22-34
Xi
36/37
F,Xn
11-20/21/22-
Xn
22
O,C
7-22-34
21-34-43
F,C
11-20/22-34
Xn
20/21/22
T+
27/28
Xn
20/22-36/37-
E,Xn
1-20/21/22
E,Xn
2-20/21/22-33
Xn,N
21/22-50/53
Xn,N
45-51/53
E,T
2-23/24/25-33
46-23/25-41-
7446-18-6
T+
52/53
28-38-48/25
7440-28-0
T+
26/28-33
T+
26/28-33
25366-23-8
Xn
22
62-55-5
45-22-36/38
28249-77-6
Xn
22
THIOCARBAMIDE
(2-)22-24-36/37-61
THIOCARBONYL CHLORIDE
(1/2-)7-9-36/37-45
THIOCYANIC ACID
(2-)13
THIOCYANIC ACID, SALTS
(2-)13 Note A
THIOCYCLAM-OXALATE
(2-)36/37-46
2,2'-THIODIETHANOL
(2)
2-THIO-1,3-DITHIOLO-[4,5-b]QUINOXALINE
(2-)24
THIOFANOX
(1/2-)27-36/37-45
THIODIGLYCOL
(2)
THIOGLYCOLIC ACID
(1/2-)25-27-28-45
THIOMETON
(1/2-)36/37-45
THIONAZIN
(1/2-)36/37/39-38-45
THIONYL CHLORIDE
(1/2-)26-45
THIOPHANATE-METHYL
(2-)36/37
THIOQUINOX
(2-)24
THIOUREA
(2-)22-24-36/37-61
THIRAM
40-43
(2-)36/37
THYMOL
(1/2-)26-28-36/37/39
TIN(II) METHANESULPHONATE
(1/2-)22-26-36/37/39-45
TITANIUM TETRACHLORIDE
(1/2-)7/8-26-45
TNT
(1/2-)35-45
o-TOLIDINE, SALTS
53-45-61 Note A, E
TOLUENE
(2-)16-25-29-33
TOLUENE-2,4-DIAMMONIUM SULPHATE
43-50/53
53-45-60-61 Note E
Page No.
35
18/11/96
62-56-6
463-71-8
22-23-36/37/38
463-56-9
Xn
20/21/22-32
Xn
20/21/22-32
31895-22-4
Xn
21/22
111-48-8
Xi
36
93-75-4
Xn
22
39196-18-4
T+
27/28
111-48-8
Xi
36
68-11-1
23/24/25-34
640-15-3
21-25
297-97-2
T+
27/28
7719-09-7
14-34-37
23564-05-8
Xn
40
93-75-4
Xn
22
62-56-6
Xn,N
22-40-51/53
137-26-8
Xn
20/22-36/37-
89-83-8
22-34
53408-94-9
22-34-43
7550-45-0
14-34-36/37
118-96-7
E,T
2-23/24/25-33
T,N
45-22-51/53
108-88-3
F,Xn
11-20
65321-67-7
T,N
45-21-25-36-
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
TOLUENE-2,6-DIISOCYANATE
(1/2-)23-26-28-38-45 Note C
91-08-7
23-36/37/38-42
TOLUENE-2,4-DIISOCYANATE
(1/2-)23-26-28-38-45 Note C
p-TOLUENESULPHONIC ACID, containing more
(1/2-)26-37/39-45
than 5% H2SO4
p-TOLUENESULPHONIC ACID, containing a maximum
(2-)26-37
of 5% H2SO4
4-TOLUENESULPHONYLISOCYANATE
(2-)26-28-30
m-TOLUIDINE
(1/2-)28-36/37-45-61 Note C
p-TOLUIDINE
(1/2-)28-36/37-45-61 Note C
o-TOLUIDINE
53-45-61 Note E
4-o-TOLYLAZO-o-TOLUIDINE
53-45
TOSYLISOCYANATE
(2-)26-28-30
TOXAPHENE
40-50/53
(1/2-)36/37-45-60-61
TRIADIMEFON
(2)
TRIALKYLBORANES
(1/2-)7-23-26-36/37/39
-43-45 Note A
TRI-ALLATE
(2)
TRIAMIPHOS
(1/2-)22-28-36/37-45
TRIARIMOL
(2)
3,6,9-TRIAZAUNDECAMETHYLENEDIAMINE
51/53
(1/2-)26-36/37/39-45-61
1,2,4-TRIAZOL-3-YLAMINE
(2-)36-37-61
TRIAZOPHOS
(1/2-)23-36/37-45
TRIBROMOMETHANE
(1/2-)28-45-61
TRIBUTYL-(2,4-DICHLOROBENZYL) PHOSPHONIUM
(1/2-)36/37/39-45
CHLORIDE
TRIBUTYL PHOSPHATE
(2-)25
TRIBUTYLTIN COMPOUNDS with the exception of
48/23/25
(1/2-)35-36/37/39-45 Note A
those specified elsewhere in this Annex
TRICHLORFON
(2-)24-37
TRICHLOROACETIC ACID
(1/2-)24/25-26-45
TRICHLOROACETONITRILE
(1/2-)45
S-2,3,3-TRICHLOROALLYL-DIISOPROPYL(2)
THIOCARBAMATE
548-84-9
34
104-15-4
Xi
36/37/38
4083-64-1
Xn
14-36/37/38-42
108-44-1
T,N
23/24/25-33-50
106-49-0
T,N
23/24/25-33-50
95-53-4
T,N
45-23/25-36-50
97-56-3
45-43
4083-64-1
Xn
14-36/37/38-42
8001-35-2
T,N
21-25-37/38-
43121-43-3
Xn
22
F,C
17-34
2303-17-5
Xn
22
1031-47-6
T+
27/28
26766-27-8
Xn
22
112-57-2
C,N
21/22-34-43-
61-82-5
Xn,N
40-48/22-51/53
24017-47-8
24/25
75-25-2
T,N
23-36/38-51/53
115-78-6
21-25-36/38
126-73-8
Xn
22
21-25-36/38-
52-68-6
Xn
22-43
76-03-9
35
545-06-2
23/24/25
2303-17-5
Xn
22
TRICHLOROANILINE
50/53
(1/2-)28-36/37-45-60-61 Note C
2,3,6-TRICHLOROBENZOIC ACID
(2)
1,1,1-TRICHLORO-2,2-BIS(4-CHLOROPHENYL)ETHANE
50/53
(1/2-)22-36/37-45-60-61
2,2,2-TRICHLORO-1,1-BIS(4-CHLOROPHENYL)(2-)36/37
ETHANOL
2,3,4-TRICHLOROBUT-1-ENE
36/37/38-40-50/53 (1/2-)36/37-45-60-61
1,1,1-TRICHLOROETHANE
(2-)24/25-59-61 Note F
1,1,2-TRICHLOROETHANE
(2-)9
2,2,2-TRICHLOROETHANE-1,1-DIOL
(1/2-)25-45
TRICHLOROETHYLENE
(2-)23-36/37-61
TRICHLOROISOCYANURIC ACID
(2-)8-26-41
TRICHLOROMETHANE
48/20/22
(2-)36/37
TRICHLORO(METHYL)SILANE
(2-)26-39
TRICHLORONATE
(1/2-)23-28-36/37-45-60-61
TRICHLORONITROMETHANE
(1/2-)36/37-38-45
2,4,5-TRICHLOROPHENOL
(2-)26-28-60-61
2,4,6-TRICHLOROPHENOL
(2-)36/37
2,4,5-TRICHLOROPHENOXYACETIC ACID
(2-)24
2-(2,4,5-TRICHLOROPHENOXY)ETHYL
(2)
2,2-DICHLOROPROPIONATE
2-(2,4,5-TRICHLOROPHENOXY) PROPIONIC ACID
(2-)37
2,3,6-TRICHLOROPHENYLACETIC ACID
(2-)36
1,2,3-TRICHLOROPROPANE
(2-)37/39 Note D
TRICHLOROSILANE
(2-)24/25-43
I,I,I-TRICHLOROTOLUENE
37/38-41
53-45 Note E
2,4,6-TRICHLORO-1,3,5-TRIAZINE
(2-)28
TRICHLORO-1,3,5-TRIAZINE-2,4,6-TRIONE
(2-)8-26-41
TRICRESYL PHOSPHATE, o-o-o, o-o-m, o-o-p,
51/53
(1/2-)20/21-28-45-61 Note C
o-m-m, o-m-p, o-p-p, conc.1%
TRICRESYL PHOSPHATE, m-m-m, m-m-p, m-p-p,
(2-)28-61 Note C
p-p-p, conc.5%
Page No.
36
Xn
22
50-29-3
T,N
25-40-48/25-
115-32-2
Xn
21/22-38-43
2431-50-7
T,N
22-23-
71-55-6
Xn,N
20-59
79-00-5
Xn
20/21/22
302-17-0
25-36/38
79-01-6
Xn
40-52/53
87-90-1
O,Xn
8-22-31-36/37
67-66-3
Xn
22-38-40-
75-79-6
F,Xi
11-14-36/37/38
327-98-0
T+,N
24-28-50/53
76-06-2
T+
22-26-36/37/38
95-95-4
Xn,N
22-36/38-50/53
88-06-2
Xn
22-36/38-40
93-76-5
Xn
22-36/37/38
136-25-4
Xn
22
93-72-1
Xn
22-38
85-34-7
Xn
22
96-18-4
Xn
20/21/22
10025-78-2
15-17
98-07-7
45-22-23-
108-77-0
Xi
36/37/38
87-90-1
O,Xn
8-22-31-36/37
T,N
39-23/24/25-
Xn,N
21/2251/53
Substance
Safety phrases
CAS number
Symbol
Risk-phrases
TRICYCLAZOLE
(2)
TRICYCLOHEXYLTIN COMPOUNDS with the exception
(2-)26-28 Note A
of those specified elsewhere in this Annex
TRI(CYCLOHEXYL)TIN HYDROXIDE
(2-)13
TRIDEMORPH
(2-)25-36/37
TRIETHOXYISOBUTYLSILANE
(2-)24
TRIETHYLAMINE
(1/2-)3-16-26-29-36/37/39-45
TRIETHYLENE GLYCOL DIACRYLATE
(2-)26-28 Note D
TRIETHYLENETETRAMINE
(1/2-)26-36/37/39-45-61
TRIETHYL PHOSPHATE
(2-)25
TRIETHYLTIN COMPOUNDS with the exception of
(1/2-)26-27-28-45 Note A
those specified elsewhere in this Annex
TRIFENMORPH
(2-)22-24
TRIFLUOROACETIC ACID, conc.>10%
(1/2-)9-26-27-28-45 Note B
TRIFLUOROACETIC ACID, 1%conc.<5%
23-26
I,I,I-TRIFLUOROTOLUENE
(2-)16-23-61
TRIFLURALINE (containing <0.5ppm NPDA)
(2-)24-37
TRIHEXYLTIN COMPOUNDS with the exception of
(2-)26-28 Note A
those specified elsewhere in this Annex
1,2,3-TRIHYDROXYBENZENE
(2)
TRILEAD BIS(ORTHOPHOSPHATE)
53-45 Note E
TRIMELLITIC ANHYDRIDE
(2-)22-28
1,2,4-TRIMETHYLBENZENE
(2-)26
1,7,7-TRIMETHYLBICYCLO(2,2,1)HEPT-2-YL
(2-)24/25
THIOCYANATOACETATE
TRIMETHYLBORATE
(2-)23-25
3,5,5-TRIMETHYL-2-CYCLOHEXEN-1-ONE
(2-)26
TRIMETHYLENEDIAMINETETRAACETIC ACID
41814-78-2
Xn
22
Xn
20/21/22
13121-70-5
Xn
20/21/22
24602-86-6
Xn
21/22
17980-47-1
Xi
38
121-44-8
F,C
11-20/21/22-35
1680-21-3
Xi
36/38-43
112-24-3
21-34-43-52/53
78-40-0
Xn
22
T+
26/27/28
1420-06-0
Xn
22
76-05-1
20-35
76-05-1
Xi
36/38
98-08-8
F,N
11-51/53
1582-09-8
Xi
36-43
Xn
20/21/22
87-66-1
Xn
20/21/22
7446-27-7
61-62-33-48/22
552-30-7
Xn
36/37/38-42
95-63-6
Xn
10-20-36/37/38
115-31-1
Xn
22
121-43-7
Xn
10-21
78-59-1
Xi
36/37/38
1939-36-2
Xn
22-36
16938-22-0
23-36/37/38-42
57-47-6
T+
26/28
15625-89-5
Xi
36/38-43
107-39-1
11
T+
26/27/28
123-63-7
11
606-35-3
E,Xn
2-20/21/22
25377-32-6
E,T+
2-26/27/28-33
28905-71-7
E,Xn
2-4-20/21/22
88-89-1
E,T
2-4-23/24/25
82-71-3
E,Xn
2-4-20/21/22
118-96-7
E,T
2-23/24/25-33
15646-96-5
43-50/53
67297-26-1
E,Xn
2-20/21/22-33
129-64-6
Xi
36/37/38
10027-06-2
Xn
21-38-43
Xi
36/37/38
110-88-3
Xn
22
110-88-3
Xn
22
Xn
20/21/22
101-02-0
Xi
36/38
900-95-8
T+,N
24/25-26-
23/24/25
T+,N
24/25-26-
23/24/25
76-87-9
Substance
Safety phrases
115-96-8
Xn
22-36/38
CAS number
Symbol
Risk-phrases
Xi
36
Xn
22-36/38
Xn
22
24/25
46-23/25-41-
T,N
52/53
39-23/24/25-
F,T+
15/29-28-32
T+
26/28
Xn
36/37/38-42
Xn
10-20/21/22
T+
26/28-33
T+
26/28-33
45
34
Xi
36-43
T,N
21-25-50
Xn
20
Xi
36/37/38
Xn
22
11
F+,T
45-12
F+,T
45-12
(TRIS(CHLOROMETHYL)PHTHALOCYANINATO)COPPER(II),
(2-)26
reaction products with N-METHYLPIPERAZINE
and METHOXYACETIC ACID
2,4,6-TRIS(DIMETHYLAMINOMETHYL)PHENOL
90-72-2
(2-)26-28
TRIS(DODECYL-3-METHYL-27276-58-6
(2-)24
PHENYLBENZIMIDAZOLIUM)HEXACYANOFERRATE
N,N,N-TRIMETHYLANILINIUM CHLORIDE
138-24-9
(1/2-)25-39-45-53
1,3,5-TRIS(OXIRANYLMETHYL)-1,3,5-TRIAZINE2451-62-9
43-48/2253-45-61 Note E
2,4,6(1H,3H,5H)-TRIONE
TRITOLYL PHOSPHATE, o-o-o, o-o-m, o-o-p,
51/53
(1/2-)20/21-28-45-61 Note C
o-m-m, o-m-p, o-p-p
TRIZINC DIPHOSPHIDE
1314-84-7
(1/2-)3/9/14-30-36/37-45
L TROPYL-TROPAT
101-31-5
(1/2-)-24-45
TRYPSIN
9002-07-7
(2-)22-24-26-36/37
TURPENTINE
(mix) 8006-64-2
(2)
URANIUM
7440-61-1
(1/2-)20/21-45
URANIUM COMPOUNDS
(1/2-)20/21-45 Note A
URETHANE
51-79-6
53-45
VALERIC ACID
109-52-4
(1/2-)26-36-45
VALINAMIDE
20108-78-5
(2-)24-26-37
VAMIDOTHION
2275-23-2
(1/2-)36/37-45-61
VANADINIUM PENTOXIDE
1314-62-1
(2-)22
VERATRINE
8051-02-3
(2-)36/37/39
VERNOLATE
1929-77-7
(2)
VINYL ACETATE
108-05-4
(2-)16-23-29-33 Note D
VINYL BROMIDE
593-60-2
53-45
VINYL CHLORIDE
75-01-4
106-87-6
23/24/25-40
75-35-4
F+,Xn
12-20-40
611-15-4
Xn
20
81-81-2
61-48/25
45-22
2655-14-3
Xn
22
108-38-3
Xn
10-20/21-38
95-47-6
Xn
10-20/21-38
106-42-3
Xn
10-20/21-38
1330-20-7
Xn
10-20/21-38
1300-71-6
24/25-34
T,N
23/24/25-33-
2425-10-7
Xn
22
2655-14-3
Xn
22
F,C
14-17-34
137-30-4
Xn
22-36/37/38-40
7646-85-7
34
T,N
45-22-43-50/53
Xi,N
36/38-51/53
T+,F
15/29-28-32
10-15
7440-66-6
15-17
7733-02-0
Xi
36/38
137-30-4
Xn
22-36/37/38-40
15
15-17
1314-84-7
7740-67-7
Group 2A
Group 2B
________________________________________________________________________________
Agent/Industrial process
CAS Number
Occupational
sources
________________________________________________________________________________
1402-68-2
4-Aminobiphenyl
92-67-1
Arsenic and
Asbestos
Azathioprine
Benzene
material
Benzidine
impurity
Beryllium and
arsenic
compounds(b)
mycotoxins
Rubber manufacture
/1.,p.1292/f
7440-38-2
Drug, pesticide
1332-21-4 Roofing, friction
material
446-86-6
Drug
71-43-2
Solvent, raw
92-87-5
beryllium
compounds(d)
N,N-Bis(2-chloroethyl)-2-naphthylamine
(Chlornaphazine)
Bis(chloromethyl)ether and
chloromethyl methyl ether (technical-grade)
1,4-Butanediol dimethanesulfonate (Myleran)
Cadmium and cadmium compounds(d)
Chlorambucil
agent
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)
Feedstuff
Raw material,
7440-41-7
Raw material,
electronics industry
494-03-1 Drug
542-88-1
Laboratory chemical
107-30-2
55-98-1 Antineoplastic agent
7440-43-9
Raw material
305-03-3
Antineoplastic
-1-nitrosourea
(Methyl-CCNU)
Chromium(VI)
compounds
manufacturing
(1990)
Ciclosporin (1990)
Cyclophosphamide
agent
Diethylstilboestrol
Erionite
Melphalan
agent
8-Methoxypsoralen (Methoxsalen) plus
ultraviolet radiation
MOPP and other combined chemotherapy
including alkylating agents
Mustard gas (Sulfur mustard)
/2.,90-110/
2-Naphthylamine
Nickel
compounds (1990)
Oestrogen replacement therapy
1.,p.1666/
Oestrogens, nonsteroidal(b)
Oestrogens,
oesteroidal(b)
(1990)
Treosulfan
agent
Vinyl chloride (monomer)
505-60-2
91-59-8
Dermatological drug
/4.,p.243/
Antineoplastic agents
War gas
Dye manufacturing
Pigment, batteries,
impurity
Hormones /
Hormones,
pharmaceutical
industry /1.,p.1666/
Hormones,
pharmaceutical
industry /1.,p.1666/
Hormones
Hormones
10043-92-2
Mining
Extenders in paints
and ceramic products
/1.,p.2141/
52-24-4
Antineoplastic agent
/2.,91-572/
299-75-2
Antineoplastic
75-01-4
Plastic industry
Mixtures
Alcoholic beverages (1988)
Analgesic mixtures containing phenacetin
Betel quid with tobacco
Coal-tar pitches
Coal-tars
Mineral oils, untreated and mildly treated
Salted fish (Chinese-style) (1993)
Shale-oils
Soots
Tobacco products, smokeless
Drugs
65996-93-2 Raw material
8007-45-2
Drug, raw material
Use of crude
oil distillates
/2.,91-960/
68308-34-9
Agent/Industrial process
CAS Number
Occupational
sources
________________________________________________________________________________
Group 2A Probably carcinogenic to humans
Acrylonitrile
Adriamycind
agent
Androgenic (anabolic) steroids
Azacitidine (1990)(d)
Benz[a]anthracene(d)
Benzidine-based dyes(d)
Benzo[a]pyrene(d)
Bischloroethyl nitrosourea (BCNU)
1,3-Butadiene (1992)
Captafol (1991)(d)
pesticides
107-13-1
23214-92-8
Raw material
Antineoplastic
/2.,pp.82-736/
Drugs
320-67-2
Antineoplastic agent
/2.,pp.91-572/
56-55-3
Impurity
Dyes
50-32-8
Impurity
154-93-8 Antineoplastic agent
106-9-90
Manufacture of
synthetic rubber
/1.,p.347/
2425-06-1
Fungicides,
/1.,pp.927-1616/
Chloramphenicol (1990)(d)
56-75-7
Antibiotics /
1.,p.171/
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea 13010-47-4
Antineoplastic
agent
(CCNU)(d)
para-Chloro-ortho-toluidine and
its strong acid salts (1990)(d)
95-69-2
Synthesis of organic
dyestuffs
/1.,pp.146-147/
Chlorozotocin (1990)(d)
54749-90-5
Antineoplastic
agent
/2.,pp.91-572/
Cisplatin(d)
15663-27-1 Antineoplastic agent
/5.,II/p.125/
Dibenz[a,h]anthracene(d)
53-70-3
Coal-tar /
IQ(d) (2-Amino-3-methylimid-azo[4,5-f]
-quinoline) (1993)
5-Methoxypsoralend
64-67-5
Raw material,
laboratories
79-44-7
Laboratories
77-78-1
Raw material,
laboratories
106-89-8
Epoxyres in
raw material,
laboratories
106-93-4
Soil fumigant,
leaded gasoline
/1.p.623/
75-21-8
Pesticide,
intermediate
759-73-9
Laboratory
of diazoethane
/6.,p.192/
50-00-0
Preservative,
disinfectant, textile,
wood/timber industry,
raw material
76180-96-6 Grilled fish
and meat
/2.,pp.92-1997/
484-20-8
Dermatological agent
/4.,p.243/
4,4'-Methylene bis(2-chloroaniline)
(MOCA) (1993)
101-14-4
N-Methyl-N'-nitro-N-nitrosoguanidine
(MNNG)(d)
70-25-7
N-Methyl-N-nitrosourea(d)
synthesis
Nitrogen mustar(d)
N-Nitrosodiethylamine(d)
N-Nitrosodimethylamine(d)
Phenacetin
Procarbazine hydrochloride(d)
Propylene oxide(d)
propylene
Silica, crystalline
Styrene oxide
additive
Tris(2,3-dibromopropyl)phosphate
Ultraviolet radiation A (1992)(d)
Ultraviolet radiation B (1992)(d)
Ultraviolet radiation C (1992)(d)
Polyurethane
industry, curing agent
Laboratory agent
/2.,pp.92-1997/
684-93-5
Laboratory
of diazomethane
/21.,p.192/
51-75-2
Basis for some
antineoplastic agents
55-18-5
Laboratories
62-75-9
Laboratories,
pollutant
62-44-2
Drug
366-70-1 Antineoplastic agent
/2.,pp.85-1341/
75-56-9
Production of
glycol /1.,p.771/
14808-60-7 Ceramic
industry /1.,p.2034/
96-09-3
Epoxy resin
/7/
126-72-7
Solar radiation
Solar radiation
Welding operation,
Vinyl
bromided
Mixtures
Creosotes
Agent/Industrial process
M1 (1993)
para-Aminoazobenzene
ortho-Aminoazotoluene
2-Amino-5-(5-nitro-2-furyl)-1,3,4thiadiazole
Amitrole
26148-68-5
Grilled food,
tobacco smoke
/9.,p.294/
75-07-0
Manufacture of acetic
acid and ethyl
acetate /1.,p.36/
60-35-5
As a solvent for
organic compounds,
plasticizer /1.,p.139/
79-06-1
Manufacture of
acrylamide polymers
/1.,p.138/
3688-53-7
Ex-food
preservative
/10.,p.48/
6795-23-9
Found in the milk
60-09-3
97-56-3
ortho-Anisidine
Antimony trioxide
(1989)
AramiteR
Atrazine (1991)
1.,p.1626/
Auramine (technical-grade)
492-80-8
Dye manufacture
/2.,pp.80-121/
115-02-6
Antineoplastic
Azaserine
agent
Benzo[b]fluoranthene
Benzo[j]fluoranthene
Benzo[k]fluoranthene
Benzyl violet 4B
205-99-2
Impurity
205-82-3
Impurity
207-08-9
Impurity
1694-09-3
Textile dye
/13.,p.155/
11056-06-7
Antineoplastic drug
/12.,p.34/
Bleomycinse(e)
Bracken fern
Bromodichloromethane (1991)
Butylated
hydroxyanisole
75-27-4
(BHA)
b--Butyrolactone
Caffeic acid (1993)
plants
Carbon-black
/11.,p.207/
Manufacture of natural
and synthetic rubber
56-23-5
Solvent, raw
extracts
Carbon tetrachloride
material
Ceramic fibres (1988)
Use in manufacture of
paper felts, furnace
/2.,91-1961/
57-74-9
Pesticide
143-50-0
Pesticide
115-28-6
Chemical
Chlordane (1991)
Chlordecone (Kepone)
Chlorendic acid (1990)
intermediate
in the manufacture of
unsaturated polyester
resins /2.,pp.90-1979/
Intermediates
106-47-8
Dye industry
67-66-3
Solvent, raw
a-Chlorinated toluenes
para-Chloroaniline (1993)
Chloroform
material
Chlorophenols
Chlorophenoxy herbicides
4-Chloro-ortho-phenylenediamine
CI Acid Red 114 (1993)
CI Basic Red 9 (1993)
CI Direct Blue 15 (1993)
Citrus Red No. 2 (CI 12156)
Cobalt and cobalt compounds
magnets
para-Cresidine
Cycasin
Intermediate
solvent /5.,II/23/
25013-16-5
Food additive
/2.,pp.87-1414/
3068-88-0
Laboratories
331-39-5
Constituent of
(1991)
Fungicides,
bactericides
/1.,p.1673/
Herbicides
95-83-0 Hair-dye component
/14.,p.83/
6459-94-5
Dye
569-61-9
Dye
2429-74-5
Dye
6358-53-8
Dye
7440-48-4
Manufacture of
/1.,p.493/
120-71-8
Dye manufacturing
14901-08-7
Naturally occurring
Dacarbazine
Dantron (Chrysazin; 1,8Dihydroxyanthraquinone)(1990)
Daunomycin
DDT (para,para'-DDT) (1991)
N,N'-Diacetylbenzidine
2,4-Diaminoanisole
4,4'-Diaminodiphenyl ether
2,4-Diaminotoluene
Dibenz[a,h]acridine
Dibenz[a,j]acridine
1.,p.460/
7H-Dibenzo[c,g]carbazole
Dibenzo[a,e]pyrene
Dibenzo[a,h]pyrene
Dibenzo[a,i]pyrene
Dibenzo[a,l]pyrene
1,2-Dibromo-3-chloropropane
para-Dichlorobenzene
3,3'-Dichlorobenzidine
3,3'-Dichloro-4,4'-diaminodiphenyl ether
1,2-Dichloroethane
material
Dichloromethane (Methylene chloride)
1,3-Dichloropropene
(technical-grade)
Dichlorvos (1991)
Diepoxybutane
Di(2-ethylhexyl)phthalate
1,2-Diethylhydrazine
Diglycidyl resorcinol ether
Dihydrosafrole
intermediate
Tobacco smoke
/17.,p.318/
192-65-4
Diesel and gasoline
engine exhaust fumes
/18.,p.33/
189-64-0
Diesel and gasoline
engine exhaust fumes
/18.,p.33/
189-55-9
Diesel and gasoline
engine exhaust fumes
/18.,p.33/
191-30-0
Diesel and gasoline
engine exhaust fumes
/18.,p.33/
96-12-8
Pesticide
106-46-7
Fumigants,
insecticides
/1.,p.460/
91-94-1
Raw material, dye
manufacturing
28434-86-8
Dye, raw material
107-06-2
Solvent, raw
75-09-2
Solvent
542-75-6 Pesticides
/2.,pp.88-1251/
62-73-7
Pesticide
1464-53-5 Raw material,
laboratories
117-81-7
Plastic industry
/1.,p.1691/
1615-80-1 Laboratory chemical
/19.,p.154/
101-90-6
Epoxy resin,
aircraft equipment
industry /20.,p.154/
94-58-6
Chemical
for manufacture of
piperonyl butoxide
/15.,p.235/
3,3'-Dimethoxybenzidine (ortho-Dianisidine)
para-Dimethylaminoazobenzene
trans-2-[(Dimethylamino)methylimino]-5-[2(5-nitro-2-furyl)25962-77-0 Limited usage as a
vinyl]-1,3,4-oxadiazole
pharmaceutical
/21.,p.148/
2,6-Dimethylaniline (2,6-Xylidine) (1993)
87-62-7
Synthesis of
other chemicals
/1.,p.142/
3,3'-Dimethylbenzidine (ortho-Tolidine)
119-93-7
Dye, laboratories
Dimethylformamide (1989)
68-12-2
Solvent for liquids
and organic compounds
1,1-Dimethylhydrazine
57-14-7
Rocket fuel
formulations, chemical
synthesis /3.,p.149/
1,2-Dimethylhydrazine
540-73-8
Chemical intermediate
/19.,p.146/
1,6-Dinitropyrene (1989)
42397-64-8
Diesel and gasoline
engine exhaust fumes
/18.,p.216/
1,8-Dinitropyrene (1989)
42397-65-9
Diesel and gasoline
engine exhaust fumes
/18.,p.232/
1,4-Dioxane
123-91-1
Raw material,
solvent
Disperse Blue 1 (1990)
2475-45-8
Dye, hair dye
Ethyl
acrylate
140-88-5
As a component of
solution for coating
textiles, paper and
leather /1.,p.53/
Ethylene thiourea
96-45-7
Raw material,
laboratories, rubber
industry
Ethyl methanesulfonate
62-50-0
Laboratories
2-(2-Formylhydrazino)-4-(5-nitro-2furyl)thiazole
3570-75-0 No use
Glasswool (1988)
Glu-P-1 (2-Amino-6-methyldipyrido
[1,2-a:3',2'-d]imidazole)
67730-11-4 Charred fraction of
cooked fish and meat
/10.,p.37/
Glu-P-2 (2-Aminodipyrido
[1,2-a:3',2'-d]imidazole)
67730-10-3 Charred fraction of
cooked fish and meat
/10.,p.37/
Glycidaldehyde
765-34-4
Acrolein metabolite
Griseofulvin
126-07-8
Antibiotic drug,
veterinary medicine
HC Blue No. 1 (1993)
2784-94-3
Hair dye
Heptachlor (1991)
76-44-8
Pesticide
Hexachlorobenzene
118-74-1
Fungicide
Hexachlorocyclohexanes
Pesticide /
1.,p.1616/
Hexamethylphosphoramide
680-31-9
Solvent
Hydrazine
302-01-2
Raw material
Indeno[1,2,3-cd]pyrene
193-39-5
Tobacco smoke,
inhalation of polluted
Iron-dextran complex
Lasiocarpine
an
Nafenopin
Nickel, metallic
(1990)
Nitridazole
Nitrilotriacetic acid and its salts (1990)
5-Nitroacenaphthene
6-Nitrochrysene
(1989)
Nitrofen, technical-grade
2-Nitrofluorene (1989)
1-[(5-Nitrofurfurylidene)amino]-2imidazolidinone
Ochratoxin A (1993)
Oil Orange SS
Panfuran S, containing
dihydroxymethylfuratrizine
Pentachlorophenol (1991)
Phenazopyridine hydrochloride
Phenobarbital
Phenoxybenzamine hydrochloride
Phenyl glycidyl ether (1989)
Phenytoin
PhIP (2-Amino-1-methyl-6-phenylimidazo
[4,5-b]pyridine) (1993)
Ponceau MX
Ponceau 3R
Potassium bromate
Progestins
1,3-Propane sultone
b-Propiolactone
Propylthiouracil
agent
Rockwool (1988)
Saccharin
Safrole
Slagwool (1988)
Sodium ortho-phenylphenate
Sterigmatocystin
Streptozotocin
Styrenee
material
Sulfallate
2,3,7,8-Tetrachlorodibenzo-para-dioxin
(TCDD)
Tetrachloroethylene
cleaning/1.,p.677/
Thioacetamide
4,4'-Thiodianiline
Thiourea
794-93-4 Drug
87-86-5
136-40-3
50-06-6
63-92-3
122-60-1
57-41-0
Pesticide
Drug /4.,p.312/
Drug /4.,p.312/
Drug /27/
Epoxy compounds
Drug /5.,II/47/
Artificial sweeteners
/28.,p.111/
94-59-7
Parfumery, soaps,
flavouring agent in
drugs /15.,p.234/
132-27-4
Fungicide
/2.,pp.84-1614/
10048-13-2 Mycotoxin
18883-66-4 Drug
100-42-5
Solvent, raw
95-06-7
Herbicide
1746-01-6
Use as an analytical
reagent in the
laboratory /1.,p.1391/
139-65-1
Dye intermediate
/27.,p.152/
62-56-6
Photocopying, raw
material
Toluene diisocyanates
ortho-Toluidine
Trichlormethine (Trimustine hydrochloride)
(1990)
817-09-4
Trp-P-1
(3-Amino-1,4-dimethyl-5Hpyrido[4,3-b]indole)
Trp-P-2
(3-Amino-1-methyl-5Hpyrido[4,3-b]indole)
Trypan blue
Uracil mustard
agent
Urethane
Antineoplastic agent
/2.,pp.91-574/
Raw material
Mixtures
Bitumens, extracts of steam-refined and
air-refined
8052-42-4
Carrageenan, degraded
9000-07-1
Food additive
Chlorinated paraffins of average carbon chain length C12 and
average degree of chlorination approximately 60% (1990)
Coffee (urinary bladder) (1991)
Diesel fuel, marine(e) (1989)
Engine exhaust, gasoline (1989)
Fuel oils, residual (heavy) (1989)
Gasoline(e) (1989)
Pickled vegetables (traditional in Asia)
(1993)
Polybrominated
biphenyls (Firemaster
BP-6)
59536-65-1 Flame
retardant
Toxaphene (Polychlorinated camphenes)
8001-35-2
Pesticide
Toxins derived from Fusarium moniliforme
(1993)
Mycotoxins
Welding fumes (1990)
Exposure circumstances
Carpentry and joinery
Textile manufacturing industry (work in) (1990)
________________________________________________________________________________
25.
26.
27.
28.
ANNEX 6.
List of chemicals banned or severely restricted to certain uses owing to their effects on health and the
environment in the countries of EU
Use
Use
Chemical
CAS number
category limitation
MERCURIC OXIDE
21908-53-2
P
SR
MERCUROUS CHLORIDE
10112-91-1
P
SR
OTHER INORGANIC MERCURY COMPOUNDS
P
B
ALKYL MERCURY COMPOUNDS
P
SR
ALKOXYALKYL AND ARYL MERCURY COMPOUNDS
P
B
ALDRIN
309-00-2
P
SR
CHLORDANE
57-74-9
P
B
DIELDRIN
60-57-1
P
B
DDT
50-29-3
P
B
ENDRIN
72-20-8
P
SR
HCH (contains < 99% gamma isomer)
608-73-1
P
B
HEPTACHLOR
74-44-8
P
B
HEXACHLOROBENZENE
118-74-1
P
B
CAMPHECHLOR (TOXAPHENE)
8001-35-2
P
B
POLYCHLORINATED BIPHENYLS (PCB), except MONO- and
1336-36-3
I
B
DICHLORINATED BIPHENYLS
POLYCHLORINATED TERPHENYLS (PCT)
61788-33-8
I
B
PREPARATIONS with a PCB or PCT content higher than 0.01% by
I
B
weight
TRIS(2,3-DIBROMOPROPYL) PHOSPHATE
126-72-7
I
SR
TRIS-AZIRIDINYL-PHOSPHIOXIDE
545-55-1
I
SR
POLYBROMINATED BIPHENYLS (PBB)
I
SR
CROCIDOLITE
12001-28-4
I
SR
NITROFEN
1836-75-5
P
B
1,2-DIBROMOETHANE
106-93-4
P
B
1,2-DICHLOROETHANE
107-06-2
P
B
AMOSITE
12172-73-5
B
ANTHOPHYLLITE ASBESTOS
77536-67-5
B
ACTINOLITE ASBESTOS
77536-66-4
B
TREMOLITE ASBESTOS
77536-68-6
B
CADMIUM and its compounds
7440-43-9
R
2-NAPHTYLAMINE and its salts
91-59-8
B
4-AMINOPHENYL and its salts
92-67-1
B
BENZIDINE and its salts
92-87-5
B
4-NITROPHENYL
92-93-3
B
LEGEND:
Use category:
P plant-protection product
I industrial chemical
Use limitation:
SR severe restriction
B ban
R restrictions
ANNEX 7.
Substances and Quantities Potential to Cause Major Accidents
No.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
Quantity
1kg
1kg
1kg
1kg
1kg
10kg
1kg
1kg
1kg
500kg
100kg
10kg
1kg
1kg
750kg
25t
50t
200t
20t
200t
500t
500t
50t
50t
50t
50t
200t
200t
200t
200t
100kg
50t
50t
100kg
200t
150kg
50t
100kg
1kg
100kg
50t
50t
100kg
CAS No.
92-67-1
92-87-5
100kg
100kg
1kg
470-90-6
535-89-7
107-30-2
62-75-9
91-59-8
7440-41-7
542-88-1
1120-71-4
1746-01-6
1303-28-2
1327-53-3
7784-42-1
79-44-7
15159-40-7
75-44-5
7782-50-5
7783-06-4
107-13-1
74-90-8
75-15-0
7726-95-6
7664-41-7
74-86-2
1333-74-0
75-21-8
75-56-9
75-56-9
107-02-8
107-18-6
107-11-9
7803-52-3
151-56-4
50-00-0
7803-51-2
74-83-9
624-83-9
11104-93-1
10102-18-8
505-60-2
4104-14-7
78-00-2
75-74-1
5836-73-7
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
HEXAMETHYLPHOSPHOROAMIDE
JUGLONE (5-HYDROXYNAPHTHALENE-1,4-DIONE)
WARFARIN
4,4'-METHYLENEBIS(2-CHLOROANILINE)
ETHION
ALDICARB
NICKEL TETRACARBONYL
ISOBENZAN
PENTABORANE
1-PROPEN-2-CHLORO-1,3-DIOL-DIACETATE
PROPYLENEIMINE
OXYGEN DIFLUORIDE
SULPHUR DICHLORIDE
SELENIUM HEXAFLUORIDE
HYDROGEN SELENIDE
TEPP
SULFOTEPP
DIMEFOX
1-TRI(CYCLOHEXYL)STANNYL-1H-1,2,4-TRIAZOLE
TRIETHYLENEMELAMINE
COBALT METAL, OXIDES, CARBONATES, SULPHIDES, as powders
NICKEL METAL, OXIDES, CARBONATES, SULPHIDES, as powders
ANABASINE
TELLURIUM HEXAFLUORIDE
TRICHLOROMETHANESULPHENYL CHLORIDE
1,2-DIBROMOETHANE (ETHYLENE DIBROMIDE)
FLAMMABLE SUBSTANCES as defined in 82/501/EEC Annex IV(c)(i)
FLAMMABLE SUBSTANCES as defined in 82/501/EEC Annex IV(c)(ii)
DIAZODINITROPHENOL
DIETHYLENE GLYCOL DINITRATE
DINITROPHENOL, SALTS
1-GUANYL-4-NITROSAMINOGUANYL-1-TETRAZENE
BIS(2,4,6-TRINITROPHENYL)AMINE
HYDRAZINE NITRATE
NITROGLYCERIN
PENTAERYTHRITOL TETRANITRATE
CYCLOTRIMETHYLENE TRINITRAMINE
TRINITROANILINE
2,4,6-TRINITROANISOLE
TRINITROBENZENE
TRINITROBENZOIC ACID
CHLOROTRINITROBENZENE
N-METHYL-N,2,4,6-TETRANITROANILINE
2,4,6-TRINITROPHENOL (PICRIC ACID)
TRINITROCRESOL
2,4,6-TRINITROPHENETOLE
2,4,6-TRINITRORESORCINOL (STYPHNIC ACID)
2,4,6-TRINITROTOLUENE
(a) AMMONIUM NITRATES1
(b) AMMONIUM NITRATES IN THE FORM OF FERTILISERS2
147 NITROCELLULOSE (containing > 12,6% of NITROGEN)
148
149
150
151
152
50t
109-13-7
50t
1931-62-0
50t
2372-21-6
50t
2144-45-8
50t
2167-23-9
50t
3006-86-8
50t
19910-65-7
50t
2614-76-8
50t
16066-38-9
50t
22397-33-7
50t
1338-23-4
50t
37206-20-5
50t
79-21-0
50t
50t
10t
169
170
171
172
173
174
175
176
50t
50t
50t
10t
50t
50t
50t
50t
13424-46-9
63918-97-8
20820-45-5;
628-86-4
2691-41-0
20062-22-0
3058-38-6
628-96-6
625-58-1
831-52-7
18810-58-7
3437-84-1
50t
14666-78-5
50t
927-07-2
CYCLOTETRAMETHYLENETETRANITRAMINE
2,2',4,4',6,6'-HEXANITROSTILBENE
1,3,5-TRIAMINO-2,4,6-TRINITROBENZENE
ETHYLENE GLYCOL DINITRATE
ETHYL NITRATE
SODIUM PICRAMATE
BARIUM AZIDE
80%)
80%)
60%)
This applies to ammonium nitrate fertilizers (defined in Directive 80/876/EEC) and to compound fertilizers
where the nitrogen content derived from ammonium nitrate is >28% by weight. The compound fertilizer may
contain also other fertilizing agents, such as phosphate and potash.
ANNEX 8.
A. General Classification and Labelling Requirements for Dangerous Substances and Preparations
The assessment of the effects on health is tested using animals. The test substance or preparation can be
applied to the animal orally, under the skin or by inhalation. LD50 and LC50 are the parameters to explain the
results of different tests so that they are comparable. LD50 is an abbreviation used for the dose which kills
50% of the test population. LC50 is an abbreviation used for the exposure concentration of a toxicant lethal to
half of the test animals.
Classification to hazard categories can be done by determining the acute toxicity in animals, expressed in
LD50 or in LC50 values and using the following limit figures
25
LC50 absorbed by
inhalation in rat,
mg/litre par 4 hours
50
0.25
Toxic
25 -200
50 - 400
0.25 to 1
Harmful
200 - 2000
400 - 2000
1 to 5
LD50 and LC50 can be found for many substances and preparations in the literature.
The substances and preparations have also other effects, like flammability. These should be included in the
assessment of hazards for final classification.
B. Concentration Limits to be used in applying the Conventional Method of Assessing Health Hazards
Tables 1 - 6. Non-gaseous substances and preparations
Tables 7 - 12. Gaseous substances and preparations
Table 1. Acute lethal effects
Classification of the substance
concentration
7%
1%
Xn
conc. < 7%
concentration
0.1%
25%
1%
conc. < 1%
conc. < 25%
concentration
25%
T+ with R39
concentration
T
10%
1%
Xn
0.1%
concentration < 1%
R39 obligatory
T with R39
R40 obligatory
concentration 10%
R39 obligatory
1%
Xn with R40
concentration 10%
R40 obligatory
The R-phrases R20 to R28 are also to be assigned to indicate route of administration or means of
exposure.
Table 3. Severe effects after repeated or prolonged exposure
Classification of the substance
T with R48
Xn
concentration 10%
R48 obligatory
1%
Xn with R48
concentration 10%
R48 obligatory
The R-phrases R20 to R28 are also to be assigned to indicate route of administration or means of
exposure.
Table 4. Corrosive or irritant effects
Classification of the
substance and/or
relevant R-phrase
at least C with
R35
C with R35
concentration
10%
C with R34
at least C with
R34
at least Xi with
R41
5%
conc. <
10%
R34 obligatory
1% conc. < 5%
R36/ R38 obligatory
concentration
10%
R34 obligatory
Xi with R41
concentration
10%
R41 obligatory
5% conc. <10%
R36 obligatory
concentration 20%
R36, R37, R38 obligatory,
if they apply
Xn and R42
concentration 1%
R42 obligatory
Xi and R43
Xn and R42/43
concentration 1%
R43 obligatory
concentration
1%
at least Xn
concentration 1%
R40 obligatory
concentration 0.1%
R46 obligatory
concentration
0.1%
R46 obligatory
concentration 1%
R40 obligatory
T with R61 for substances causing birth defects of category 1 or concentration 0.5%
2
R61 obligatory
Xn with R63 for substances causing birth defects of category 3
T with R60 for substances impairing fertility of category 1 or 2
concentration 5%
R63 obligatory
concentration 0.5%
R60 obligatory
concentration 5%
R62 obligatory
concentration
1%
T with R23
0.2%
Xn with R20
concentration 0.02%
< 1%
concentration
5%
0.5%
concentration <
0.2%
concentration <
5%
concentration
5%
T+ with R39
concentration 1%
R39 obligatory
0.2%
T with R39
Xn
concentration < 1%
R39 obligatory
concentration 5%
R39 obligatory
Xn with R40
concentration 5%
R40 obligatory
The R-phrases R20, R23 or R26 are also to be assigned to indicate route of administration or means of
exposure.
Table 9. Gaseous preparations; severe effects after repeated or prolonged exposure
Classification of the substance (gas)
T with R48
Xn
concentration 5%
R48 obligatory
Xn with R48
0.5%
concentration < 5%
R48 obligatory
concentration 5%
R48 obligatory
The R-phrases R20 or R23 are also to be assigned to indicate route of administration or means
of exposure.
Table 10. Gaseous preparations; corrosive or irritant effects
Classification of the
substance (gas)
C with R35
C with R34
conc. 1%
R35 obligatory
concentration
< 1%
R34 obligatory
0.2%
concentration 5%
R34 obligatory
0.5%
concentration <
5%
R37 obligatory
0.5%
concentration <
5%
R36 obligatory
Xi with R41
conc. 5%
R41 obligatory
concentration 5%
R36, R37, R38 obligatory, if
they apply to the
substances
concentration 0.2%
R42 obligatory
Xn and R42/43
concentration 0.2%
R42/43 obligatory
concentration 0.1%
R45, R49 obligatory
at least Xn
concentration 1%
R40 obligatory
concentration 0.1%
R46 obligatory
concentration 0.1%
R46 obligatory
concentration 1%
R40 obligatory
concentration 0.2%
R61 obligatory
concentration 1%
R63 obligatory
concentration 0.2%
R60 obligatory
concentration 1%
R62 obligatory
ANNEX 9.
United Nations Classification Recommendation on Transport of Dangerous Goods
List of Classes
1. EXPLOSIVES
1.1.
Substances
and
articles
which
have
a
mass
explosion
hazard
1.2. Substances and articles which have a projection hazard but not a mass explosion hazard
1.3. Substances and articles which have a fire hazard and either a minor blast hazard or a minor
projection
hazard
but
not
a
mass
explosion
hazard
1.4.
Substances
and
articles
which
present
no
significant
hazard
1.5.
Very
insensitive
substances
which
have
a
mass
explosion
hazard
1.6. Extremely insensitive articles which do not have a mass explosion hazard
2. GASES
2.1.
Flammable
gases
2.2
Non-flammable,
non-toxic
gases
2.3. Toxic gases
3. FLAMMABLE LIQUIDS
4. FLAMMABLE SOLIDS
4.1.
Flammable
solids
4.2.
Substances
liable
to
spontaneous
combustion
4.3. Substances which in contact with water emit flammable gases
5. OXIDIZING SUBSTANCES; ORGANIC PEROXIDES
5.1.
Oxidizing
substances
5.2. Organic peroxides
6. POISONOUS (=TOXIC) SUBSTANCES
6.1.
Toxic
substances
6.2. Infectious substances
7. RADIOACTIVE MATERIAL
8. CORROSIVE SUBSTANCES
9. MISCELLANEOUS DANGEROUS SUBSTANCES
First-aid measures
Fire-fighting measures
Spillage, accidental release measures
Handling and storage
Exposure controls and personal protection
Physical and chemical properties
Stability and reactivity
Toxicological information
Ecological information
Disposal considerations
Transport information
National regulations and references
Other information
Chemical safety data sheets should be available within the enterprise for every chemical substance that has
been classified as hazardous. They should also be available for preparations (products) containing any of the
hazardous substances as components.
Chemical safety data sheets are published under several names, such as:
2. Composition/information on ingredients
The information on the ingredients enables the user to identify readily the relevant risks. For preparations it is
not necessary to reveal the full composition. However, substances which are known to present a health
hazard and substances for which an exposure limit value has been given should be included in the safety
data sheet with an indication of the concentration range (for example, the substances listed in `Identification,
Classification and Labelling of Dangerous Chemicals', Annex 4)
To identify the possible hazards of a substance, its chemical name should be compared with preferred names
of dangerous substances from existing lists or data bases.
To identify the ingredient substances of a preparation other information besides the name of the substance
may be included, for example, the Chemical Abstract Service number (CAS No) and/or the number given in
the Register of Toxic Effects of Chemical Substances (RTECS) number and/or the number given in the
European Inventory of Existing Commercial Chemical Substances (EINECS).
Even if certain substances are to be kept confidential, their chemical nature and the potential hazards
associated with that substance should be described. They should also have an unambiguous generic name.
3. Hazard identification
Under this heading should be given brief and clear descriptions of the most important hazards the substance
or the preparation creates for man, the environment or property.
Also the most important adverse human health effects and symptoms should be listed here. Furthermore,
these should all be related to the use and possible misuse that can reasonably be foreseen.
This information should be compatible with that shown on the product label but need not repeat it.
exposure by inhalation
exposure by skin and eye contact
ingestion
5. Firefighting
The information provided here can be used to plan appropriate fire and emergency procedures.
Indicate suitable extinguishing media, as well as incompatible extinguishing media that must not be used. For
example in fires of organic solvents, such as toluene, foam, carbon dioxide or dry chemical, but not water,
should be used.
Mention special exposure hazards caused by the substance or preparation, such as combustion products or
released gases. The need for firefighters' special protective equipment should be specified, if necessary.
for respiratory protection specify adequate masks and the filter type
for eye protection specify the type of protective equipment, such as safety glasses, safety goggles,
face shield
for hand protection specify the type and material of gloves to be worn when handling the substance or
preparation. An example of the importance of choosing the right material is that polyvinyl alcohol
(PVA) provides good protection against toluene diisocyanate but offers poor resistance to
trichloroethylene.
for skin protection specify the type and quality of equipment required, such as an apron, boots or full
protective suit. Indicate also the specific hygiene measures, such as eating or smoking prohibition
during handling, or washing methods.
Autoflammability:
Extremely flammable relates to liquids which have a flash point below 0C and a
boiling point below 35C, and to flammable gases when liquified.
-some materials have the feature of igniting in air in the absence of a spark or flame.
mobility
persistence and degradability
bioaccumulative potential
aquatic toxicity and other data, such as behaviour of the substance or preparation in sewage works.
Pay special attention to the properties of substances classified as being dangerous to the environment and
which are present in the preparation, such as aerosols that contain halogenated hydrocarbons hazardous to
the ozone layer.
IDENTIFICATION
Do you have the right card for the chemical with which you are working or will be working?
Do you have an up-to-date card?
POTENTIAL HAZARDS
PREVENTIVE MEASURES
EMERGENCY MEASURES
BIBLIOGRAPHY
CALLAGHAN J.M., DUMSCHAT C.J. and WHITING R.F., The Material Safety Data Sheet, A Basic Guide for
Users, Canadian Centre for Occupational Health and Safety, Hamilton 1987
CIS, Finnish National Board of Labour Protection, Machine Translated Finnish Chemical Safety Information
Sheets
91/155/EEC Commission Directive of 5 March 1991 defining and laying down the detailed arrangements for
the system of specific information relating to dangerous preparations in implementation of Article 10 of
Directive 88/379/EEC
ILO, International Labour Organisation, Code of Practice on Safety in the Use of Chemicals at Work, Geneva
1992
ILO, International Labour Organisation, Convention No. 170 Concerning Safety in the Use of Chemicals at
Work, Geneva 1990
ILO, International Labour Organisation, Recommendation No. 177 Concerning Safety in the Use of Chemicals
at Work, Geneva 1990
ILO, International Labour Organisation, Encyclopedia of Occupational Health and Safety, Vol I - III, Geneva
1983
risk of explosion
fire and smoke
chemical health hazards: immediate or delayed poisoning, burns, allergies
damage to the environment
Many companies allow uncontrolled access by diesel engines believing that they cannot ignite gas or vapour.
This is incorrect:
Four tons of hot, flammable hydrocarbon leaked out of the a plant while maintenance work was in process. A
diesel engine was on in the area. The flammable vapour was sucked into the air inlet and the engine started
to race. The driver tried to stop the engine by stopping the the fuel supply (usual way of stopping a diesel
engine) but without success as burning material was coming in through the the air inlet. Finally there was a
flash-back and the flammable liquid was ignited to a fire.
Another frequent incident is this type:
a tank trailer tipped up because of the rear compartments were emptied first. If it is not possible to keep trailer
connected to the truck,s driving unit the front comparments should be filled last and emptied first as the
normal support cannot alone prevent the trailer from tipping.
Picture 21
Picture 22
Picture 23
Picture 24
Picture 25
explosive
liable to spontaneous ignition or combustion
liberate flammable gases on contact with water
contain infectious microorganisms that are known or reasonably believed to cause disease in animals
or humans
radioactive
compressed, condensed or pressurized dissolved gases, or organic peroxides
Class
3017
6.1
1396
1005
1789
1011
4.3
2.3
8
2.1
Hazards
Subsidiary
risk
3
Risks involved
When flammable solids are handled there is a possibility of large amounts of dust being released in the air.
These mixtures of dust and air can lead to a dust explosion.
Many flammable solids give off hazardous fumes when they are burned. For example, the fumes of burning
sulphur or red phosphorous are toxic and corrosive.
The decomposition of self-reactive substances can be initiated by heat, contact with catalytic impurities
(acids, bases, heavy metal compounds), friction or impact. Decomposition may result in the emission of toxic
gases and vapours. In order to ensure safety during transport, a self-reactive substance may be desensitized
using a diluting agent compatible with the substance.
2.6 Class 4.3. Substances which in contact with water emit flammable gases
Carbides are among the substances in Class 4.3. An extremely flammable gas, acetylene, is produced by
adding water to calcium carbide. When sodium comes into contact with water it gives off hydrogen gas. The
reaction is violent and produces enough heat to ignite hydrogen. Hydrogen burns explosively with such a hot
flame that metallic material can start to burn.
Aluminium and magnesium powders, zinc dust and some metal hydrides are in this class.
Risks involved
In addition to the dangers of fire and explosion, goods belonging to this class can react with moisture on
human skin and cause burns.
neutral (water)
The pH value can often be found on the label or in the documents following the substance.
Some countries require that solutions must be classified, because of the corrosive effects, when the pH value
is less than 1.5 or greater than 11.5.
The pH of some common substances in dilute water solutions is given below:
Concentration
1%
1%
1%
1%
Substance
Hydrochloric acid
Acetic acid
Sodium hydroxide(caustic
soda)
Ammonia
Smell
sharp
typical
pH
~0.6
~2.8
Effect on skin
Slight feeling
None
none
~13.4
Strong
sharp
~11.4
Irritating
Acids and alkalis are normally transported at very high concentrations, e.g. 90-95% sulphuric acid, 65% nitric
acid, 30% hydrochloric acid, 50% sodium hydroxide and 50% phosphoric acid. At these concentrations the pH
value is not important, the substances are simply very corrosive.
Risks involved
These substances can attack and corrode many materials, for example, clothe, paper and several metals.
Decomposition often produces heat and gases, and in some cases extremely flammable hydrogen gas. The
choose of a packing material and loading should carefully planned, because it can be some time before the
consequences of corrosive effects are visible.
Accidental mixing of different corrosive materials can in some cases lead to violent reactions, which may give
off large amounts of gases.
In the case of strong alkalis ther is a latent period before a burning feeling on the skin is experienced. By then
the damage is already done. Skin contact with strong acids produces an immediate feeling. Both types of
corrosive substances can cause serious skin damages.
Corrosive material in the eyes requires a very rapid and long rinse with water (for at least 15 minutes) and
medical attention.
Primary
Subsidiary
Primary
Methanol
Subsidiary
Dibenzoyl peroxide
Keep dry
This way up
Fragile
In addition:
Other elements of information deemed necessary by national authorities, such as flash point.
If dangerous waste is transported for disposal, the proper shipping name should be preceded by the
word "WASTE"
b) Declaration or certificate that the consignment offered can be accepted for transport, and that the goods
are properly packed, marked and labelled.
Picture 31
Picture 32
Picture 33
Picture 34
Picture 35
4. Organizing safety
Safety measures should be considered from the request for transport up to the delivery at the end- point,
including the cleaning of the vehicle afterwards.
All levels of personnel involved should be well informed and these people should share the responsibility.
Safety measures should include organizational, personnel and engineering aspects, and co-operation
between operational staff during the transport should be emphasized.
point out practical problems concerning either the workplace as a whole or individual tasks;
create a forum to discuss these problems and to try to find solutions that improve the health of
workers and reduce loss of materials;
find out the risks of the work and the effects of these risks and to suggest a solution to minimize
them.
establish a priority list of improvements, with respect to time and resources;
ensure that the suggested practical solutions are properly implemented and the results are improving
the situation;
promote good housekeeping in the working environment.
This should involve all parties in the workplace. The task could be given to a committee including
representatives of different parts of the transport company.
The committee could consider emergency planning and safety education. Ideas from both workers and the
employer should be encouraged and discussed.
4.3. Responsibilities
It is the responsibility of the consignor to see that
goods are classified according to national and international regulations
the limitations on the transport of certain goods are respected
the goods are properly packed and marked
the appropriate documents are attached to the goods
The responsibilities of the transporter are
to equip the vehicle to meet national and international regulations
to see that the workers and drivers are trained to transport dangerous goods
to plan the transport, e.g., to select routes avoiding dense residential areas, and to arrange
supervision during parking.
The driver of a vehicle is responsible for
having necessary documents for the load at hand
accepting only undamaged, marked or labelled packages and containers
Specimen labels
Annex 1. Common rules that apply to all types of transport of dangerous goods
Annex 2. Quantity limits
Annex 3. Goods requiring supervision
Annex 4. Labels and document for transport of dangerous goods
Annex 5. Hazard identification numbers on placards
Picture 41
Picture 42
Picture 43
Picture 44
Picture 45
BIBLIOGRAPHY
The training module is based on the Swedish education material:
ARBETARSKYDDSNMNDEN, Transport av farligt gods, Sjuhradsbygdens Tryckeri AB, Boras 1985, ISBN
91-574-1346-0
ARBETARSKYDDSNMNDEN, Handbok fr vgtransport av farligt gods, Stockholm 1993
ILO, International Labour Organisation, Encyclopedia of Occupational Health and Safety, Vol I - III, Geneva
1983
IPCS, International Programme on Chemical Safety and CEC, Commission of the European Communities,
International Chemical Safety Cards
Kletz, T.A., What Went Wrong? Case Histories of Process Plant Disasters, Gulf Publishing Company, Houston
1988
UNITED NATIONS, Transport of Dangerous Goods, 8th Ed., New York 1993
UNITED NATIONS, European Agreement concerning the international carriage of dangerous goods by road
(ADR) and protocol of signature, New York 1992
ANNEX 1.
COMMON RULES THAT APPLY TO TRANSPORT OF DANGEROUS GOODS
Read the transport document(s) before loading in order to master the loading and to know what to do in case
of an accident or spill
Do not leave the vehicle containing dangerous goods unattended
Loading and unloading of some dangerous goods in public places requires the presence of or notice to
authorities (police, customs)
Do not take passenger(s)
No smoking during loading operations, or close to a vehicle that is waiting to be unloaded, or inside the
vehicle
Never use open flames of any kind in the area where there are dangerous or unknown goods Do not keep
engines running when they are not needed for loading (pumping, lifting...)
See that the goods, the names and the amount are the same in reality as in the enclosed documents
See that dangerous goods do not come into contact with food and feedstuff
See that the labels are placed on the dangerous goods and on the vehicle
Separate dangerous goods from other goods that are transported and place them properly (make a sketch
where they are located in the vehicle)
See that the load can not move during the transport (well fixed, no oil on floor that would make it slippery) See
that there is available the necessary equipment to conduct (un)loading and transport safely (e.g. grounding
cables, personal protection equipment)
Do not accept for transport damaged dangerous goods or leaking packages or containers
Drivers have no right to open packages or containers with dangerous goods
ANNEX 2
If following QUANTITY LIMITS for dangerous goods that are packed and distributed for sale through retail
agencies for consumption for personal care or household use are not exceeded, in this case no transport
documents, proper shipping names or UN numbers are required to be attached during the transport.
List of values for quantity limits for personal care and household use: (from UN Recommendation on the
transport of dangerous goods)
Class
Packing group
State
ANNEX 3.
GOODS REQUIRING SUPERVISION
Compiled from the European Agreement concerning the international carriage of dangerous goods by road
(ADR).
The lists of goods and substances in different classes presented below are not comprehensive.
Transport units carrying dangerous goods in quantities above the values indicated should be supervised or,
alternatively, may be parked unsupervised in an isolated location in the open at a secure depot or factory
premises.
Class
1. Explosives:
2. Gases:
Toxic or
corrosive:
Goods
Weight
Nature of
requiring surveillance
surveillance
over 50 kg all the time
1000 kg
limited
1000 kg
limited
limited
limited
limited
limited
limited
Limited
limited
limited
limited
Class
Flash point
below 21C,
corrosive
4.1 Flammable
solids:
Explosive
substances in
the nonexplosive state
Self-reactive
substances
Self-reactive
substance
Self-reactive
substances
4.2
Substances
liable to
spontaneous
combustion:
4.3
Substances
which in
contact with
water emit
flammable
gases:
5.1 Oxidizing
substances:
1000 kg
limited
100 kg
1000 kg
limited
limited
100 kg
limited
limited
10 000 kg
limited
500 kg
1000 kg
2000 kg
5000 kg
limited
5.2 Organic
peroxides:
6.1 Toxic
substances:
Highly toxic,
flash point
below 21C
Highly toxic,
flash point
21C or more
Highly toxic, in
contact with
water or acids
emit toxic
gases
limited
limited
limited
Class
Highly toxic
Highly toxic,
used as
pesticides,
rodenticides
Toxic, flash
point 21C or
more
Toxic, in
contact with
water or acids,
emit toxic
gases
Toxic
Dibutyl tin chloride, arsenic trichloride, arsenic pentoxide, various 5000 kg
arsenites, mercuric acetate, mercuric chloride, mercury nitrates,
selenium disulphide, selenium dioxide, vanadates
Toxic, used as Chlorfenvinphos, Chlormephos, Demeton-S-methyl, Dialifos,
5000 kg
pesticides,
Dichlorvos, Dicrotophos, Dioxathion, Endothion, Ethion, Mecarbam,
rodenticides
Methamidophos, Methidathion, Monocrotophos, Oxydemetonmethyl, Parathion-methyl, Phospholan, Phosphamidon, Propaphos,
Schradan, Sulfotep, Triamiphos, Trichloronat, Aldrin, Dieldrin,
Endosulfan, Heptachlor, Isodrin, Pentachlorophenol, Dinoseb,
Dinoterb, DNOC, Aminocarb, Carbofuran, Dimetilan, Formetanate,
Isolan, Mercaptodimethur, Methomyl, Mexacarbate, Oxamyl, PMA,
Chloro-methoxyethyl mercury, Coumaphos, Coumatetralyl,
Paraquat
7. Radioactive
substances:
8. Corrosive
Bromine
1000 kg
substances:
Highly
Chromosulphuric acid, sulphur trioxide, oleum, red fuming nitric
10 000 kg
corrosive
acid, mixtures of sulphuric acid with more than 30% of nitric acid,
aqueous solutions (60-85%) of hydrofluoric acid, selenic acid,
chlorosulphonic acid, chromyl chloride, disulphur dichloride,
sulphuryl chloride, thionyl chloride, sulphur dichloride, boron
bromide, trifluoracetic acid, aqueous solutions (more than 64%) of
hydrazine, allyl chloroformate, benzyl chloroformate
9.
5000 kg
Miscellaneous:
Substances
Crocidolite, amosite
which, on
inhalation as
fine dust, may
endanger
health
Substances
PCB, PTB and their mixtures (over 50 mg/kg)
limited
limited
limited
Class
Goods
and
apparatures
which in event
of fire may
form dioxins
ANNEX 4
LABELS AND DOCUMENT FOR TRANSPORT OF DANGEROUS CHEMICALS
recommended by the United Nations
ANNEX 5
HAZARD IDENTIFICATION NUMBER PLACARD
The following identification system is in use for placards in Europe (ADR) for road transport. The background
of the placard is orange. The border, horizontal line, and figures are black. Identification numbers are shown
in such a way, that the upper number is indicating the danger and the lower number identifies the substances
with the UN-number given in the UN Recommendations on the Transport of Dangerous Goods.
333
X333
336
338
X338
339
36
362
X362
38
382
X382
39
40
423
X423
44
446
46
462
48
482
50
539
55
556
558
559
56
568
58
59
60
63
638
639
66
663
68
69
70
72
723
73
74
75
76
78
80
X80
83
SECTION 6. SOLVENTS
Exposure to solvents and other organic liquids is one of the most common chemical health risk at places of
work. Most of the organic solvents are combustible, often highly volatile and extremely flammable and they
should always be handled with care. Some solvents produce vapours which are heavier than air. These may
move on the floor or ground to a distant ignition source, such as a spark from welding or caused by static
electricity. The vapours may also explode from smoking. Vapours of solvents can also accumulate in confined
places and stay there for a long time, presenting risks for health and property.
Solvents enter the body by inhalation, by swallowing and through the skin. The effect depends on several
factors, such as
Solvents, their vapours and mists have various effects on human health. Many of them have a narcotic effect,
causing fatigue, dizziness and intoxication. High doses may lead to unconsciousness and death.
Exposure to large doses of solvents may slow down reaction- time and affect rational judgement. This may
increase the risk of accidents both at work and outside, such as in the traffic on the way back home.
Solvents irritate the eyes and the respiratory tract.
Solvents clean and defat not only metal plates in industrial processes but also the skin. This is a very
common cause of skin disorders and dermatitis. Some solvents penetrate the skin and enter the blood
circulation.
Solvents may damage the liver, kidneys, heart, blood vessels, bone marrow and the nervous system.
The solvents which pose the most serious risk to health should be substituted by less hazardous ones. If this
is not possible with regard to the workprocess, at least the conditions during handling should be adjusted so
that there is no risk of skin contact and that the concentration of vapour in the air is kept low. This may be
achieved, for example, by using a closed process. Amongst the most hazardous solvents are benzene,
carbon disulphide and carbon tetrachloride.
Solvents are excreted in urine and sweat or they may be exhaled.
Workplace controls and practices
Good work practices and training can help to reduce hazardous exposures. For most of the hazardous
solvents it is possible to find a substitute with the same characteristics but less drastic effects on health.
Ventilation is important and it should be considered carefully when using solvents.
Equipment (fire extinguishers, absorbant material, etc.) should be considered and provided for situations such
as spillage or emergency.
Personal protective equipment such as aprons, gloves and masks with filters should be available where
needed, and they should be used according to the recommendations. Storage of this equipment should be in
a clean place away from possible contact with solvent vapours.
BENZENE
Benzene is a colourless, flammable liquid with a pleasant odour. It is used as a solvent in many areas of
industries, such as rubber and shoe manufacturing, and in the production of other important substances such
as styrene, phenol and cyclohexane. It is essential in the manufacture of detergents, pesticides, solvents and
paint removers. It is present in fuels such as in gasoline up to the level of 5%.
The Threshold Limit Value (TLV) in the workplace air over an 8- hour working day (as recommended in many
countries) is 10 ppm (or 32 mg/m3). Some countries recommend even lower levels. The odour threshold is 12
ppm. The odour serves only as a warning of exposure. If you are handling benzene without smelling it, this
does not mean that there is no exposure.
Health effects
Benzene enters the body through inhalation and it may pass through the skin. Exposure to low concentrations
of benzene vapour or to the liquid which has penetrated the skin may cause dizziness, lightheadedness,
headache, loss of appetite and stomach upset. Exposure can also irritate the nose and throat. High
exposures to benzene may cause irregularities in the heart beat which can lead to death.
Repeated exposure can damage the bone marrow, which is the blood-forming organ, causing a condition
called aplastic anaemia. This may also lead to death.
Long-term health effects may follow when exposure to benzene has lasted for a long period of time; several
months or years. Benzene is a cancer-causing substance: a carcinogen. There is sufficient evidence that
benzene causes leukaemia in exposed workers. Many scientists say that there is no safe level of exposure to
a carcinogen.
Benzene may cause birth defects in animals. Until further testing has been done it should be handled very
carefully as a possible agent causing birth defects in humans as well.
In several countries there are severe restrictions for using and selling benzene.
Workplace controls and practices
As a solvent benzene can be substituted with a variety of less hazardous ones. Toluene is a similar solvent
to benzene. It has the general adverse effects of solvents but it has been shown neither to cause cancer nor
to damage the bone marrow. White spirit is often used as a substitute for more dangerous solvents. Less
volatile solvents, such as xylene and mesitylene, have the same type of characteristics as toluene. Gasoline
should never be used as a substitute. It may contain benzene, tetraethyl lead or other hazardous substances.
Engineering control is the most effective way of reducing exposure where substitution is not possible.
Operations with benzene can be enclosed and/or exhaust ventilation can be provided at the site of chemical
release. Isolation of operations can also reduce exposure.
Personal protective equipment, for example, breathing protection, is sometimes necessary although less
effective. However, recommendations are only guidelines and may not apply to every situation.
Benzene is filtered with a mask and filter type A (for organic solvents with boiling point over 65 C). Improper
use of the respirator is dangerous. The best choice would be a helmet with fresh air supply and a face piece
operating with positive pressure, blowing clean air from inside the helmet or hood outward. Not all types of
gloves can resist the strong solvent power of benzene. Viton or PVA gloves are recommended although even
they have limited resistance to benzene.
Restrict persons from the area of spill unless they wear protective equipment.
Remove all ignition sources.
Ventilate the area of spill or leak.
Absorb the liquid in inert material, such as vermiculite, dry sand, earth and deposit in sealed
containers.
Do not wash benzene into the sewage system. It may cause an explosion. Benzene is a hazardous
waste.
BIBLIOGRAPHY
ARBETARSKYDDSNMNDEN, Kemiska hlsorisker, Gummessons Tryckeri, Falkping, Sweden, 1990
The Dutch Institute for the Working Environment and The Dutch Chemical Industry Association, Chemical
Safety Sheets 93/94, Alphen aan den Rijn, 1993
Guidance Note EH 40/90, Health and Safety Executive Occupational Exposure Limits, UK January 1990
SECTION 7. METALS
Approximately 35 metals are of major concern in regard to occupational exposure. Two thirds of them can
cause health hazards if not properly handled and may result in well-defined toxic effects in humans. Some
metals are not poisonous in small amounts and may, on the contrary, be necessary for good health. On the
other hands, some metals, even in small doses, may cause both immediate and chronic poisoning. Damage
may involve disturbances of the blood composition or nervous system, or injury to the liver or kidneys. Longterm exposure to certain metal compounds may cause cancer. Allergic reactions may result from repeated
long term contact with some metals and metal compounds.
Mercury, lead, cadmium, nickel, chromium, manganese, arsenic, antimony, zinc, copper, cobalt, vanadium
and beryllium are used in industry and are known to cause adverse health effects both as the metal and as
metallic compounds.
As a rule, acute poisoning results from inhalation of dust, fume or vapour dispersed in the workplace air.
Intake of some metals and their compounds is also possible through the skin.
Mercury is absorbed into the body through the inhalation of fumes. Mercury compounds may also pass
through the skin. Mercury causes damage to the nervous system. In the environment, mercury is converted to
an organic compound, methylmercury, which accumulates, for example, in fish and passes through the food
chain to humans. This compound is known to affect unborn babies. Mercury compounds are present in
chlorine production and mining and are used, for example, in tanner's mordant, pickling baths and pesticides.
Cadmium is a component of some solder metals and baths used for electroplating. It is used in Ni-Cd
batteries. PVC plastics may contain cadmium stearate as a heat stabilizer. Many pigments contain cadmium
compounds, often to make yellow or red colours.
The human body lacks the ability to expel this metal from its system. Practically all the cadmium taken in
during the lifetime is stored in the kidneys, which gradually results inreduced kidney function.
Cadmium and its compounds are environmental and marine pollutants. Many countries have banned or
severely restricted certain uses of cadmium compounds.
Nickel is used in the production of a wide range of alloys, including stainless steel. Nickel is a sensitizing
material; nickel allergy is fairly common where nickel or its compounds are worked with, for example, when
plating with nickel. Some nickel compounds also cause cancer.
Chromium, especially in salt and as chromic acid, is widely used in different types of industry. Chromium is
part of stainless steel and several other alloys, it is used in electroplating various metal parts, from electrical
equipment to car parts. Chromium compounds are used in dyeing of textiles and they can be present in small
amounts in concrete. Chromium compounds may cause cancer and are sensitizing.
Manganese is a component of many alloys, and is also used in making steel. Dust and smoke from mines
and smelting plants contain this metal and its compounds. It is also a component of welding electrodes which
likewise releases dust and fumes. Manganese exposure weakens the defense system of the body against
infections and may seriously damage the nervous system.
Zinc and copper are often components of the fumes causing `metal fever'.
LEAD
Properties
Care must be exercised when handling lead or its compounds as they are cumulative poisons. This means
that exposure to lead and its compounds causes a 'lead burden'. The normal lead burden is the amount of
lead derived from the environment (air, water, soil) mainly through food. Working conditions may add to the
total lead burden.
The Threshold Limit Value (TLV) for lead compounds, such as lead acetate, lead arsenate, lead carbonate
and lead phosphate, is 0.15 mg/m3. The TLV is 0.05 for lead chromate and tetraethyl lead. For total dust, lead
metal and most of its inorganic compounds, the TLV is 0.1 mg/m 3 in some countries.
In the EU countries lead compounds are classified either as harmful: Xn, or toxic: T.
Health effects of lead
Lead can be absorbed into the body through the respiratory tract or from the stomach. Some lead compounds
penetrate the skin, such as tetraethyl lead, which is used in fuel as an antiknock agent. About one third of
inhaled lead fumes is absorbed. One tenth of ingested lead is absorbed.
Once lead has entered the human body it causes adverse effects. It combines with red blood cells causing
anaemia. Lead also settles in bones taking the place of calcium. It can be found in the liver and kidneys.
Lead affects the nervous system, including the brain.
Lead may pass through the placenta from mother to the unborn baby and it is found in milk if the mother has
been exposed.
Worker and/or their representatives should have access to the results of lead-in-air measurements and the
statistical results of medical findings.
BIBLIOGRAPHY
ARBETARSKYDDSNMNDEN, Kemiska hlsorisker, Gummessons Tryckeri, Falkping, Sweden, 1990
BAKAR CHE MAN A. and GOLD D., Safety and Health in the use of Chemicals at Work: A training manual,
ILO, Geneva, 1993
leakage of a flammable substance, mixing of the substance with air, formation of a flammable vapour
cloud and drifting of the cloud to a source of ignition leading to a fire or an explosion.
leakage of toxic substances, formation of a toxic vapour cloud and drifting of the cloud.
These clouds would directly affect the site as well as possibly the surrounding populated areas. In the case of
flammable substances the greatest danger arises from sudden massive escape of volatile liquids or gases. If
the cloud were ignited, the effects of combustion would depend on many factors, such as wind speed and the
extent to which the cloud was diluted. The area affected would generally be limited to a few hundred metres
from the site.
Much larger areas can be dangerously affected in a sudden release or by very large quantities of toxic
materials. In favorable conditions such a cloud can still contain lethal concentrations of toxic chemicals
several kilometers from the accident site. The extent of casualty depends on the number of people in the path
of the cloud and on the efficiency of emergency arrangements, for example, evacuation before the cloud
reaches the populated areas.
The effect can also migrate into other factories situated nearby and containing flammable, reactive or toxic
chemicals, escalating the disaster. This is sometimes referred to as the `domino effect'.
Not only does the cloud itself pose a health hazard, but the fires cause depletion of oxygen and fumes
generated by the fire may contain toxic gases.
Chlorine and ammonia are the toxic chemicals most commonly used in quantities large enough to pose a
major hazard. Both have a history of major accidents. There are also other chemicals which, although used in
smaller quantities should, be handled with particular care because of their higher toxicity.
An industrial accident classified as a `major hazard' leads to tighter control, more specific than that applied in
the normal factory operations. This is in order to protect both workers and outside people, to avoid economical
losses to the factory and damage to the environment.
The first step in a systematic approach is to identify the installations susceptible to a `major hazard'. For this
purpose, EU in Europe has a Directive which has been in use since 1984. The Directive sets certain criteria
based on the toxic, flammable and explosive properties of the chemicals. For the selection of specific
industrial activities which involve a `major hazard' risk, a list of substances with limit amounts is provided. The
list contains 180 toxic substances whith the limits varying from 1 kg for extremely toxic substances to 50 000
tons for highly flammable liquids. (See the list in the section: `Identification, Classification and Labelling of
Chemicals', Annex 7.)
Criteria for Major Hazard Installation
1. Very Toxic (Category 1 and 2) and Toxic substances (Category 3)
Substances classified to hazard categories below according to their acute toxicity.
LC50 absorbed by
inhalation in rat
(mg/litre per 4 hours)
<0.10
0.1 - 0.5
0.5 - 2
2. Flammable substances
3. Substances which may explode when in contact with a source of ignition or which are more sensitive to
shock and friction than dinitrobenzene.
The industrial activities creating the risk of a major hazard may not be restricted to defined sectors.
Experience has shown that such installations are most commonly associated with the following activities:
To set priorities a shortened list of Major Hazard Chemicals is provided to be used as a guide. Priorities can
also be set within the factory to identify the most hazardous areas in the production activities.
Below is a list of priority chemicals used in identifying major hazard installations.
Name of the substance
General flammable substances
Flammable gases
Highly flammable liquids
Specific flammable substances
Hydrogen
Ethylene oxide
Specific explosives
Ammonium nitrate
Nitroglycerine
Trinitrotoluene
Specific toxic substances
Acrylonitrile
Quantity
EC list number
200 t
50 000 t
124
125
50 t
50 t
24
25
2500 t
10 t
50 t
146 b
132
145
200 t
18
500 t
25 t
250 t
50 t
20 t
200 t
50 t
250 t
100 t
22
16
148
17
19
20
94
149
180
150 kg
750 kg
36
15
CHLORINE
Cases
Chlorine poisoning in Sri Lanka
A case of chlorine poisoning in a 37-year-old mechanical supervisor at a water purification plant in Sri
Lanka is described. Manipulating the main cylinder valve, he was exposed to chlorine fumes for a few
seconds as he was running in and out to stop the gas flow. He started to have an intense feeling of
suffocation and tightness of chest, coughing, intolerable irritation of eyes and mouth, headache and
stomach problems. He still had symptoms 27 days after the incident.
Transport accident
A massive chlorine release as a result of a tank leak in a car carrying chlorine took place in Norway. A
total of 85 people, from 6 months to 82 years of age were hospitalized, and out of those 3 died.
approximately 7-8 tons of chlorine gas formed a 10 km long cloud which covered the valley.
Facts about chlorine
It is a greenish-yellow gas with a pungent odour. Chlorine is heavier than air and the cloud formed tends to
spread along the ground. It can fill cellars or flow into subway tunnels as it did in an accident in New York
leading to the hospitalization of 208 persons.
Chlorine is chemically very active. Dry chlorine at ambient temperatures reacts directly with many materials
including metals. Dry chlorine does not attack steel and it is supplied commercially in steel containers in liquid
form under pressure.
As liquid chlorine evaporats, at boiling point (-340 C), one volume unit of liquid forms 457 volume units of
gas.
Traces of moisture in chlorine lead to rapid corrosion of steel, copper and nickel. Chlorine react vigorously
with organic compounds including mineral oils and greases. Mixtures of chlorine and hydrogen gases are
explosive.
Chlorine dissolves in water at a rate of 6.5 g of chlorine to one litre of water at ambient temperature. The
solution is acidic and corrosive, and it has oxidizing, bleaching and germicidal properties. The water solution
in a process should be kept above a temperature of 9.60 C in order to avoid blockages as a result of
formation of solid chlorine hydrate.
The reactivity of chlorine strongly limits the choice of materials used in construction when planning an
installation. A system constructed of steel must itself be dry before allowing chlorine to enter in it. Titanium is a
satisfactory construction material at temperatures well below 1000 C provided that the moisture level is kept
high. Titanium is resistant only to wet chlorine, and consideration should be given to a possible fault where dry
Time
Effect
10
10-20
100-150
300-400
1000
1 min
30 min
5-10 min
30 min
A few breaths
Causes burning feeling which can be tolerated, if not other ill effects,
for up to 1 hour
Coughing
Dangerous-immediate irritation of nose, throat and eyes
More vulnerable persons might die
Predicted average lethal concentration for active, healthy people
Likely to be fatal
Gas filters are effective against chlorine only at low concentrations. Filter type B can be used for
concentrations below 0.1 % by volume. If the colour of chlorine gas is visible the concentration exceeds the
recommended exposure limit mentioned above (TLV).
BIBLIOGRAPHY
CLAYTON G.D. and CLAYTON F.E., ed., Patty's Industrial Hygiene and Toxicology, 3rd Revised Ed., John
Wiley & Sons Inc., USA 1978
82/501/EEC Council Directive of 24 June 1982 on the major accident hazards of certain industrial activities
87/216/EEC Council Directive of 19 March 1987 amending Directive 82/501/EEC on the major-accident
hazards of certain industrial activities
East African Newsletter on Occupational Health and Safety, Supplement 2/ 1989, Institute of Occupational
Health, Finland 1989
ILO, International Labour Organisation, Encyclopedia of Occupational Health and Safety, Vol I -III, Geneva
1983
ILO, International Labour Organisation, Major Hazard Control, A Practical Manual, 2nd Ed., Geneva 1990
ILO, International Labour Organisation, Prevention of Major Industrial accidents, Code of Practice, Geneva
1991
IPCS, International Programme on Chemical Safety, Environmental Health Criteria 21, Chlorine and
Hydrogen Chloride, WHO, Geneva 1982
IPCS, International Programme on Chemical Safety and CEC, Commission of the European Communities,
International Chemical Safety Cards, Chlorine ICSC#126
UNITED NATIONS, Transport of Dangerous Goods, 8th Ed., New York 1993
chemicals.
INTRODUCTION
The language of chemical safety is drawn from many sources. These include medicine, toxicology,
pharmacology, epidemiology, ecotoxicology and environmental pollution. Its terminology has developed in an
unstructured manner with proliferation into multiple terms, some with overlapping, alternative, or even
ambiguous meanings. This situation is a source of confusion to both authors and readers of publications on
chemical safety and a cause of difficulty in translation into other languages.
To facilitate international communication and comprehension, economy should be exercised in the use of
terms and definitions already formulated by various scientific bodies. However, this glossary is not, on the one
hand, an exhaustive compilation nor, on the other, a definitive list of approved terms. It is intended to be a
guide of terms widely used and adequately defined.
Grateful acknowledgement is made to the experts in the scientific bodies which form the sources for the terms
and definitions. In particular the work of the International Epidemiological Association in sponsoring a
Dictionary of Epidemiology, ably edited by Dr John M. Last, deserves credit for providing a sound international
basis for terminology in this field of science. The glossary has drawn heavily on this publication.
Language and terminology are not static. Comments and suggestions for additions and improvements would
be welcomed by the International Programme on Chemical Safety. These should be sent to:
The
International
Division
World
1211
Switzerland
Programme
of
Health
Geneva
Manager
on
Environmental
Chemical
Safety
Health
Organization
27
NOTE
Users of the Glossary should note that the terms in the Glossary are defined primarily for use in the
Environmental Health Criteria of the International Programme on Chemical Safety (IPCS) and in other IPCS
publications, such as those resulting from the activity of the Joint FAO/WHO Expert Meeting on Food
Additives (JECFA) and the Joint FAO/WHO Meeting on Pesticide Residues (JMPR). The terms may be used
differently by other bodies and in other publications.
abiotic: This is a term used to describe anything which is characterized by the absence of life or incompatible
with life. In toxicology and ecotoxicology it refers to physical (e.g. heat, sunlight) or chemical processes (e.g.
hydrolysis) that are capable of modifying chemical structures.
Disease
No disease
Exposed
a
c
Unexposed
b
d
True status
Diseased
Not diseased
Positive
a
b
Negative
c
d
Total
a+c
b+d
a.
Diseased
individuals
detected
by
the
test
b.
Nondiseased
individuals
positive
by
the
test
c. Diseased individuals not detectable by the test
d. Nondiseased individuals negative by the test (true negatives)
Total
a+b
c+d
a+b+c+d
(true
positives)
(false
positives)
(false negatives)
d
Specificity= -------b+d
a
REFERENCES
BIPM (1977) Le systme international d'units(SI) Svres, Bureau international des Poids et Mesures.
BISHOP, C.A. (1957) EJC policy statement on air pollution and its control. Chem. eng. Process, 53(11): 146170.
DUSTMAN, E.H. & STICKEL, L.F. (1969) The occurrence and significance of pesticide residue in wild
animals. Ann. N.Y. Acad. Sci., 160: 162-170.
FINNEY, D.G. (1971) Probit Analysis, 3rd ed., London, Cambridge University Press.
HAGAN, J.M. (1959) Acute toxicity. Q. J. Assoc. Food Drug Off., 22: 17-25.
IAEA (1978) Particle size analysis in estimating the significance of airborne contamination, Vienna,
International Atomic Energy Agency (Technical Report Series No. 179).
IARC (1977) IARC monograph programme on the evaluation of the carcinogenic risk of chemicals to humans,
Lyon, International Agency for Research on Cancer (Technical Report No. 77/002).
ICRP (1965) Principles of environmental monitoring related to the handling of radioactive materials. Report of
Committee IV of the International Commission on Radiological Protection, Oxford, Pergamon Press.
ICRP (1977) Radiation protection. Recommendations of the International Commission on Radiological
Protection, Oxford, Pergamon Press (Annals of the IPRP, Publication No. 26).
ICRU (1980) Radiation quantities and units, Washington, DC, International Commission on Radiation Units
and Measurements (ICRU Report No. 33).
ILO (1977) Code of practice on occupational exposure to airborne substances harmful to health, Geneva,
International Labour Office (MELE/1977/V).
ISO (1972) Nuclear energy glossary, Geneva, International Organization for Standardization (ISO, 921).
ISO (1975) Vibration and shock - Vocabulary, Geneva, International Organization for Standardization (ISO,
2041).
ISO (1977) Statistics - Vocabulary and symbols, Geneva, International Organization for Standardization (ISO,
3534).
ISO (1979) Cleaning equipment for air or other gases - Vocabulary, Geneva, International Organization for
Standardization (ISO, 3649).
ISO (1980) Air quality: General Aspects - Vocabulary, Geneva, International Organization for Standardization
(ISO, 3649).
ISO (1981) Terms and definitions used in connection with reference materials, Geneva, International
Organization for Standardization (ISO Guide 30).
IUPAC (1972) Manual of symbols and terminology for physicochemical quantities and units. Appendix:
Definitions, terminology and symbols in colloid and surface chemistry.Pure appl. Chem., 31: 577-638.
ICSC
ILO
IMDG
IMO
IPCS
IRPTC
ISO
IUPAC
LC50
LD50
MARPOL
MSDS
NBS
NIOSH
NTP
NTP
O.LD
OECD
OEL
OSHA
RTECS
SOLAS 74
STEL
TDG
TLV
TSCA
TWA
UN/CETDG
UN No
UNRTDG
UNEP
UNESCO
VI.LC50
VP
WHMIS
WHO