Beruflich Dokumente
Kultur Dokumente
Unicompartmental
Knee Arthroplasty
Todd Borus, MD
Abstract
Thomas Thornhill, MD
Unicompartmental
Knee Arthroplasty in the
Surgical Treatment of
Osteoarthritis
In the 1970s, several studies cast
doubt on the benefit of UKA as a sur-
Figure 1
study of 102 knees treated with either TKA or UKA, Newman et al5
showed that patients in the UKA
group had less perioperative morbidity, regained knee motion more rapidly, and had a higher percentage of
excellent outcomes based on the
Bristol knee score. Kinematics of the
knee after unicompartmental replacement have provided insight
into why patients may perceive a
more nearly normal knee function
after UKA. For example, Patil et al6
studied the kinematics of stair
climbing in a dynamic cadaveric
model and found that, with regard to
tibial axial rotation and femoral rollback, UKA more closely resembles
Indications for
Unicompartmental
Knee Arthroplasty
Classic Indications
Several algorithms have been
proposed to identify surgical candidates for UKA. Kozinn and Scott11
provided a framework of indications
and contraindications. Their criteria include a diagnosis of unicompartmental osteoarthritis or osteonecrosis in either the medial or
lateral compartment; age >60 years
with a low demand for activity;
weight <82 kg (181 lb); minimal pain
at rest; range of motion (ROM) arc
>90 with <5 flexion contracture;
and an angular deformity <15 that
is passively correctable to neutral.
Specific contraindications to UKA
are a diagnosis of inflammatory arthritis; patient age <60 years; high
patient activity level; pain at rest
(which may indicate an inflammatory component to the arthropathy);
and patellofemoral pain or exposed
bone in the patellofemoral joint or
opposite compartment. Asymptomatic chondromalacia in the patellofemoral joint is not a contraindication.
In an analysis of the surgical pathology from 4,021 knee arthroplasties, Ritter et al12 noted that only
6.1% of knees met these anatomic
qualifications for UKA and only
4.3% also met clinical standards ideal for UKA. Recent papers have
shown that with strict adherence to
the criteria of Kozinn and Scott, gratifying results can be achieved.13
Expanding Indications
Despite these generally wellaccepted and stringent selection
guidelines, recent studies have reported excellent results even as
these traditional indications are expanded. Some of the broadened criteria relate to patient demographics
such as age and weight. Pennington
Volume 16, Number 1, January 2008
Preoperative
Assessment
Preoperative
clinical
decisionmaking in assessing a patient for
UKA includes a detailed patient history, physical examination, and radiographs. One particularly important aspect of the history is that the
patient should localize his or her
pain to either the medial or lateral
joint line, with minimal indication
of pain in the opposite compartment
or the retropatellar region. Bert24 has
labeled this concept the one-finger
test. Asked to locate his or her pain,
the patient points to the involved
compartment with one finger. This
concept is in contradistinction to
the patient who performs a knee
grab when asked to localize his or
her pain, indicating more global pain
distribution.
Routine radiographs include a
weight-bearing anteroposterior, a 45
flexed-knee posteroanterior, a lateral, and an axial patellofemoral view
to assess for degeneration of adjacent
compartments and to evaluate for tibiofemoral subluxation, which may
indicate ligamentous insufficiency.
We do not routinely use MRI or arthroscopic evaluation during the
preoperative assessment. The ultimate decision to proceed with UKA
is made intraoperatively, when the
status of the other compartments
can be directly visualized.
12
Design Considerations
for Successful
Unicompartmental
Knee Arthroplasty
General Principles
Design of UKA implants continues to evolve in terms of geometry,
materials, fixation techniques, and
bearing surfaces. Generally, successful implant design relies on the following principles. First, implant design should permit stable, long-term
fixation to host bone. Second, the
sagittal and coronal plane geometry
between the femoral and tibial components should strike a balance between optimizing contact area and
limiting constraint. Limiting contact area can minimize polyethylene
contact stresses and wear; overconstraint can lead to accelerated loosening. Both Schai et al25 and Hodge
and Chandler26 reported an increased
rate of prosthetic loosening in UKA
designs with more constrained topography. Because knee kinematics
are driven by the cruciate ligaments
and the unresurfaced compartment,
a fixed bearing UKA cannot be fully
conforming.
Fixed-bearing Versus
Mobile-bearing Design
Fixed-bearing tibial components
can be either all polyethylene or
metal backed. One of the earliest
fixed-bearing designs was the Marmor prosthesis (Smith & Nephew,
Memphis, TN), introduced for clinical use in the early 1970s.27 The
original Marmor prosthesis was designed with a tibial component that
was cemented on cancellous bone
within the cortical rim as an inlay
prosthesis. As design modification
progressed, metal backing was introduced in the 1980s in an attempt to
more evenly distribute weightbearing stress to the underlying tibial bone. The modularity of metalbacked components also facilitates
easier femoral component insertion
during the cementing process and allows the possibility of isolated poly-
Failure Mechanisms:
Implications for Surgical
Technique
Although good long-term survivorship has been reported in recent studies, important causes of long-term
failure of UKAs include wear, loosening, and adjacent compartment degeneration.32,33 The relative incidence
of each of these factors varies. In an
analysis of UKA in a communitybased registry of 516 UKAs implanted by 23 different surgeons,
Gioe et al32 found an overall survivorship of several different fixed-bearing
designs of 88.6% at 10 years. Mean
time to revision surgery was 3.62
years (range, 5 months to 8.4 years).32
Progression of arthritis in uninvolved
compartments was the most com-
mon cause for revision (51%), followed by aseptic loosening, polyethylene wear or osteolysis, and
unexplained pain. The authors did
not indicate whether adjacent compartment degeneration requiring revision occurred in the contralateral
tibiofemoral compartment, the patellofemoral compartment, or a combination of the two. In contradistinction, an outcome analysis of 1,135
revised UKAs from the Swedish registry indicated that the primary reason for revision was component loosening (43% of cases), followed by
progression of adjacent compartment
arthrosis (26%) and other mechanical
problems (15%).33
Review of the literature indicates
that surgical technique at the time
of the index procedure can minimize
each of the modes of failure, potentially improving the results of
present and future procedures. As
with any arthroplasty procedure,
once adequate implant fixation has
been achieved, component positioning and alignment and soft-tissue
balancing are essential to obtaining
success (Figure 2).
Patellofemoral and
Opposite Compartment
Degeneration
The patellofemoral joint may be
subject to progressive deterioration
after either medial or lateral UKA.
Hernigou and Deschamps34 analyzed
the patellofemoral complications
following 99 UKAs at a mean
follow-up of 14 years. They noted
two distinct entities responsible for
patellofemoral symptoms that affected clinical outcome: progressive
osteoarthritis and component impingement on the patella. Progression of osteoarthritis occurred in
38% of knees when referenced to
preoperative radiographs. Incongruity on the preoperative axial skyline
radiograph was an important predictor of the joint-space narrowing seen
at final follow-up. Femoral component impingement on the patella occurred in a distinct subset of 28% of
13
Figure 2
cases and was associated more frequently with lateral UKA and anterior placement of the femoral component.
Others have stressed the importance of avoiding component oversizing and placing the femoral component in congruity with the
anterior femur in the sagittal plane
14
Some have postulated that overcorrection of joint alignment transfers increased weight-bearing force
to the opposite tibiofemoral compartment, thereby accelerating degeneration. Squire et al35 reported
progression of contralateral compartment degeneration in 46% of
136 knees at 11 years in their series.
However, Berger et al13 reported that,
at a 10- to 13-year follow-up, only
18% of knees had progressive loss of
joint space in the contralateral tibiofemoral compartment, none of
which caused symptoms requiring
revision. The authors postulated
that an overall undercorrection of
deformity in this patient series
might have been responsible for the
low rate of degeneration of the opposite compartment. The average preoperative deformity in this series
was 8 of varus from the mechanical
axis, and the average postoperative
alignment remained in 2 of mechanical varus. To prevent overcorrection, the authors recommend not
performing a formal medial collateral ligament release and inserting a
polyethylene insert that allows
2 mm of joint laxity in full extension
and flexion.
The primary concern regarding
undercorrection of deformity has
traditionally been that the prosthesis
would be vulnerable to accelerated
wear and/or tibial component loosening. Despite these concerns, no revisions in the series by Berger et al13
were performed for tibial component
loosening, wear, or subsidence.
Component Wear and
Loosening
The cause of wear in UKA is multifactorial. At the manufacturing
level, wear has been correlated with
the shelf age of the polyethylene tibial component sterilized by gamma
irradiation in air. Collier et al36
found that, with revision as an end
point, the 6-year survival in a series
of 100 UKAs was 96% when the
shelf age of the insert was <1.7 years
but only 71% when the shelf age
Figure 3
Figure 4
was >1.7 years.36 These authors postulated that discrepancies in polyethylene quality and shelf age may
partially account for the wide range
of wear rates and survivorship of implants between studies, even when
the same modular tibial component
was used. Surgeons are encouraged
to obtain the sterilization date from
manufacturers to better guide implant choices and to understand the
potential effect of shelf age on outcomes.
A comparative study by Emerson
et al29 demonstrated that the longterm primary mode of failure differs
between fixed and mobile bearing
UKAs depending on surgical technique. In 51 fixed-bearing UKAs, the
primary reason for revision was tibial component failure (eg, polyethylene wear, aseptic loosening, subsidence of the tibial component).
However, because of concern for
mobile-bearing instability, the 50
mobile-bearing implants were implanted with a tendency to stuff the
involved compartment, with a resultant overcorrection of deformity.
Volume 16, Number 1, January 2008
Figure 5
Most implant systems provide a mechanism for ensuring balanced flexion and extension gaps. Intraoperative photographs
demonstrate spacer blocks placed in the (A) flexion and extension (B) spaces, thereby confirming equality.
Summary
Unicompartmental knee arthroplasty continues to evolve, and studies
show that the procedure can result
in excellent outcomes. Satisfying
clinical results have been reported
over three decades; however, debate
continues regarding the intricacies
of the surgical technique, fixation
methods, and optimal implant design. Adherence to strict surgical indications and appropriate patient selection, combined with meticulous
surgical execution, are important
factors in optimizing outcome. The
role of minimally invasive surgery
and computer navigation should be
subject to further study to more directly define the role of this procedure.
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References
Evidence-based Medicine: Level I/II
prospective, randomized studies include references 4, 5, 28, 30, and 42.
Lesser comparative level II studies
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