Documentation

NO

PICTURE

NO

PICTURE

Materials that needed for experiment

Tools that needed for experiment

Recrystallization
1.

2.

Weighted 1 gram of salicyclic acid

(white powder)

Entered 1 gram of salicyclic acid into

erlemeyer 125 mL

Organic chemistry || recrystallization and production of aspirin experiment 26

3.

4.

Added 5 mL of water into erlemeyer

that contain of salicyclic acid
5.

Added 5ml of ethanol and heated the

solution in electric stove until boiled
while shaking
6.

Cooled the solution

7.

Filter the solution with buchner funnel

and filter paper that has been weighted
8.

Residue is white crystal

Dried in exicator until 1 day

Organic chemistry || recrystallization and production of aspirin experiment 27

9.

10.

Crystal form from recrystallization

process
Tested the melting point
11.

12.

Weighted the crystal after dried for 1

day

Entered some of aspirin into test tube

and tested with FeCl3 (purple black
color)

Preparation of aspirin
No

Picture

1.

No

Picture

2.

Weighted 5 grams of salicyclic acid

(white powder)
Entered salicyclic acid into erlemeyer
125 mL

Organic chemistry || recrystallization and production of aspirin experiment 28

3.

4.

Weighted 3,75 grams of acetic acid

anhydrate (colorless solution)

Added acetic acid anhydrate into

erlenmeyer that contain of salicylic acid
5.

6.

added 3 drops of H2SO4 concentrated to

the solution that contain salicyclic acid
and acetic anhydrate

Salicylic acid + acetic

acid
anhydrate is little soluble and still
poudery

Organic chemistry || recrystallization and production of aspirin experiment 29

7.

8.

The result after heated the solution is

soluble andd after cooled formed crystal
Input into water with temperature
50C - 60C and stirred for 5
minutes
9.

10.

Added 37,5mL of water into the

erlenmeyer
11.

After added water the crystal become

soluble and white turbid solution
12.

The solution was filtered by buchner

funnel
Residue is white crystal and filtrate is
turbid(-) solution

Organic chemistry || recrystallization and production of aspirin experiment 30

13.

14.

Put the residu into erlemeyer

Added 7,5mL of ethanol 96% (colorless

solution) into the erlenmeyer
15.

16.

added 25 mL of water into the

erlenmeyer (the solution become
white turbid solution)
17.

Added 5mL
erlenmeyer

of

ethanol

into

the

18.

added water sep by step into the

erlenmeyer until the solution become
colorless

After heated the

colorless solution

solution

Organic chemistry || recrystallization and production of aspirin experiment 31

become

19.

20.

after cooled, form crystal and turbid

solution

21.

Filter the solution with buchner funnel

and filter paper that has weighted

22.

Residue is white crystal

Dried the residue in exicator until 1 day
23.

24.

The crystal form from Preparation of

aspirin experiment

Weighted the crystal after dried for 1

day

Organic chemistry || recrystallization and production of aspirin experiment 32

25.

26.

Tested the melting point

Entered some of aspirin into test tube

and tested with FeCl3 the crystal is
purple/violet

Organic chemistry || recrystallization and production of aspirin experiment 33