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  • Tablet Triturates SB

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    Mirza Salman Baig
    1K Ansichten13 Seiten
    Tablet triturates are solid oral dosage forms made by moulding potent drugs into individual doses. They contain little binder and are formulated with diluents like lactose to rapidly disperse in the mouth or under the tongue. The preparation method involves making a smooth paste of the drug and diluent with liquid, then pressing it into holes in an upper plate placed over a lower plate with pegs. The paste hardens on the pegs and is left to dry. The individual doses are intended for quick dissolution to release the potent drug. Pills are also small solid oral doses that were traditionally made by hand-rolling but are now less common than compressed tablets and capsules.

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    Tablet Triturates SB

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    Tablet triturates are solid oral dosage forms made by moulding potent drugs into individual doses. They contain little binder and are formulated with diluents like lactose to rapidly disperse in the mouth or under the tongue. The preparation method involves making a smooth paste of the drug and diluent with liquid, then pressing it into holes in an upper plate placed over a lower plate with pegs. The paste hardens on the pegs and is left to dry. The individual doses are intended for quick dissolution to release the potent drug. Pills are also small solid oral doses that were traditionally made by hand-rolling but are now less common than compressed tablets and capsules.

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    © All Rights Reserved
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    1K Ansichten13 Seiten

    Tablet Triturates SB

    Hochgeladen von

    Mirza Salman Baig
    Tablet triturates are solid oral dosage forms made by moulding potent drugs into individual doses. They contain little binder and are formulated with diluents like lactose to rapidly disperse in the mouth or under the tongue. The preparation method involves making a smooth paste of the drug and diluent with liquid, then pressing it into holes in an upper plate placed over a lower plate with pegs. The paste hardens on the pegs and is left to dry. The individual doses are intended for quick dissolution to release the potent drug. Pills are also small solid oral doses that were traditionally made by hand-rolling but are now less common than compressed tablets and capsules.

    Copyright:

    © All Rights Reserved
    Als PDF, TXT herunterladen oder online auf Scribd lesen
    Markieren Sie unangemessene Inhalte
    von 13

    Tablet Triturates &

    Pills

    (Dr.) Mirza Salman Baig


    Assistant Professor (Pharmaceutics)
    AIKTC, School of Pharmacy,New Panvel
    Affiliated to University of Mumbai (INDIA)

    Defination and types


    Tablets are solid unit dosageform,
    prepared by compression or
    moulding.
    Compressed
    Chewable
    Coated

    Moulded
    Tablet triturates
    Pills

    Tablet triturates
    Tablet triturates are are unit
    dosageform of potent drug made
    by moulding method, intended for
    oral or sublingual administration.

    Principle
    Rapidly dispersible
    Disintegrate quickly

    Formulation
    They contain little or no binder.
    Since they are used for
    administration of potent drug
    diluents are important additive.
    Lactose ( or ), sucrose, mannitol
    They contain triturations

    Method of preparation
    Apparatus used is upper plate with
    several holes and plate with
    corrosponding pegs
    Smooth paste of drug and diluent
    made with some liquid
    Paste is pressed into holes with
    spatula into upper plate which is kept
    on tile.
    Filled Upper plate is placed on lower
    plate (with pegs)
    Paste retain on pegs left to dry at
    room temperature.

    Apparatus for moulding

    Container/storage
    Air tight container or Well closed
    plastic or glass jar.
    Packing in single row in a tube with
    closure.

    PILLS
    Small oval solid unit dosageform for
    oral use
    They can be coated to mask the
    taste of bitter taste substance.
    Now a days they have been replaced
    by compressed tablets and capsule

    Formulation

    Diluents
    Adhesive- Acacia mucilage
    Preparation
    The API is triturated with powdered
    excipients in serial dilutions to attain a
    uniform mixture.
    Liquid excipients that act to bind and
    provide plasticity to the mass are
    subsequently added

    Steps of Preparation
    Preparation of mass
    Rolling
    Cutting
    Rounding
    Coating

    Advantages/ Disadvantages
    Spherical and easy
    to swallow
    Easy to make
    Economical

    Difficult to make on
    large scale
    Disintegration
    uncertainty
    Non uniform
    Low hygiene

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