CHUONG 1 HOA HOE GLUCID6. Cig thie ny ‘A. Malose HOH HOH B. Saccarose_ ‘0. +—0, C.tawese ‘D. Heparin a E Calle 1. Dango su dy ng a i: A Frotose Ghose C.Matose D Sacarse E Lasowe 8. Dung osu dy age gil tng st: A Gate B.Frtose ©. Ghuease Dotactose E Mame 9. ‘Ci chat sau dy, chit ndo duge ding dé thim do chiie nang Ige eta clu thn: A. eprin B, Cellulose ©. Destin Dna Elesula 10. Chat no sau diy thutmg diing dé thay thé huyét tuong: ‘A lelin B. Glucose Lactose : B.Calose E Dexen 11. Bung ni su ly than gia vo thi phn cu tg cde ADN, ARN: ‘A. Galactose va Glucose B. Fructose va Lactose. Ribose vi Glucose i D. Ribose va Ribulose —_E. Deoxyribose vi Ribose 12, Hepa ob vat ‘A. Dong méu va lim trong huyét B Ching dng mu va im trong hut rong C. Ching ng nu vi lim duc hye tng D, Dong mau va lam dye huyét tuong E, Cie ¥ én déu sai. Tite 13 db cu 16 1 ca tren ede kit sau 1. Amylose o6 tr 15 > 20% va amylopectin ti 80 ~ 85%. 2, So v6ithinh phin clu tgo cia tinh bgt th phn tre edu tric nhinh nhiéu hon, nhumng 36 glucose trén cdc nhink lai agin hon 3. Dang dé thm do chic nang cd oe edu thn, 4.6 4 nhét cao nén ding a8 thay thé huyét tuong, 5. Buge clu tgo tre B+D-glucose, khéng bi thy phn & ngudi 6. La glu dy tr 6 hye vat7. La glucid dy tri 6 dng vit 8. Day la duimg sta. 13. Chon cu ding cho inulin: AL? B57 cs D3 E13 14. Chon tip hop ding cho glycogen: ALB B.1,2,6 1,27 D244 ELS 15. Chon stu ding cho dng lactose li: AL? B23 cs D6 Es 16. Chon tp hop diimg cho tinh bgt: A136 B.1,4,6 CLS D.LT E16 17. Phin ng Molish st c6 mau gi ki dung dh ch oglu: A. Xanh ie B. Ving 8 tim D.cam E.Niugach 18. Chon tép hop diing di voi glucose: 1. During 06 6 carbon mang chite aldehyd 2. Dango 6 carbon mang chic ceton 3. Cog thie dang a-D-elucopyranose bn nt 4. Saccarose tao thinh 2 pnt glucose 5. Glycogen tgo thanh tir durtmg don glugose ALAS B35 cas D235 Bua glucose Li ‘A. Aldopentose B.Cetopentose —_C. Aldohexose D.Cetohexose ——_-E. Aldohaptose 20. Chon tip bgp ding cho ding eb chie aldose: ‘A. Glucose ~ galactose ~ arabinose ~ ribulose 'B. Mannose ~ fructose ~ galactose ribose C. Brythrose — ribose ~ mannose - giycose . Mannose — glucose ~ xylulose — gglactose EE, Threose— xylose - mannose ~fraghose21. Chon tip hgp ding cho dug c6 tinh kh: ‘A. Glucose - mannose ~ saccarose ~ fructose BB, Mannose ~ ribose ~ galactose ~ tinh bot . Saccarose ~ arabinose ~ galactose ~ fructose 1. Galacfose— glucose — fructose ~ribose , Glucose ~ saccarose ~ fructose - mannose 22, Céng tht ny gen HOH E-e-D-galactopyranose 23, Dung ndo sau ly khng 6 tinh quang host: A.Giyeeraldehyt —B,Dioxyaceton —_C. Ribose D. Fructose E. Glucose H-o=0 24. Ch ny ls H-G-0H A. Acid saccarid on CH H-C-OH H-G-OH p 00H 25. Chit no sau dy thu logipolysacarid tp: ‘A. Dextran B. Amylopectin C. Heparin D. Cellulose E.Sedoheprulose Tic ed 26 dén 33 da vio cdc dt ligu sau, chon edch dién cho Ang vi tr HO ‘CH,OH H-C—OH ‘O CHO HOH eon H-d-on pelcn — ae ea -H20H "20H du,0H bu,0H “wy @) © Oo}26, 2, 28 2. 30, 31 32... 3, CHO HO HO CHOH who on Hobe HO-C—H HO-¢-H on Ho- HO-C—H H-G-on H-d-oH H--0H H-C-OH H-0-OH Hoon Gon HeOH CH2OH HOH ‘CHZOH © © © @ + D-Glucase D-Galactose Dioxyaceton D-Mannose D-Ribulose --D-Ribose -D-Fractose D-Glyceraldehyt 34. Tép hop nio sau dy kh thiy phi chi cho ra. dung c-D-Glucose ‘A. Maltose - Saccharose — Tinh bt B. Maltose ~ Lactose ~ Glycogen C. Maltose — Glycogen ~ Tinh bgt D. Heparin ~ Maltose — Glycogen EE, Sucerose — Lactose ~ Maltose 35. Khi pha a-D-Glucose vio dung dich thi hign tugmg. chuyén quay bit du ti: A.+ 112°2 ti gic quay dn inh a+ 18°7 B. + 112°2 ti ge quay én dinh a + 52°7 C+ 18°7 16 gd quay bn inh a+ 52°7 D. +18°7 i gb quay bn dh a+ 37°2 E.+ 63°26 ge quay bn dinh + 37°2 CH.OH 36. Cong them HOH A.a-D-Fructofuranose B. o-D-FructopyranoseC.a-D-Glucopyranose D.a-D-Glucofuranose E. a-D-Galactofuranose 37. Cée chkt anu dy Kn thy phn du cho ra glucose NGOAL TRU: A Maltose B. Amylose C. Glycogen D. Heparin E.Amylopectin “ igu nfo sau dy KHONG DUNG v6i glactose ‘A. La ding phi epime cia glucose & C2 B Li dng phn epime cia glucose & C, CC. Tham gia cfu tgo durimg lactose D. LArmétaldobexose E. Tham gia cl to lipid tap Tit edu 39 dén cd 42 hdy dea vo cbc sé lieu sau ddy ad tre Iai: HOCH MeOH GHAOH HOH Hoc, a D Kop (a ft (a) @) © o ® 39... D-Glucose 40......o-D-Fructose Ale... -0eD-Galactose 42......0-D-Mannose Tré Idi ede edu ie 43 din 45 cua vo cdc ot ign sau GH:OH CHLOH — GHOH O, 0, O- "HO! (A) @)je CH:OH ‘COOH 0, oO. J a YONA ) ) | © o 43... Saccarose 4... Lactose (dang B) 45... Maltose (dang a) 46. Céc chit sau fy 18 PS thuin NGOAI TRU: A.Celllose ——-B. Tisha C. Insulin H, D.Dexein E.Amplopestin | 47. Bb phn big 2 dri SC v8 6C, ng ta thy ha pin | ‘A.Selivanoff ——B. Barfoed C.t08 \ D.Molish E Bal | . \ ity dea vi cc it sw yr 0 ec ed dt 48 i 0 ‘A Phin ng Molish B.Phin ing Bial . Phin ng Batfoed | D. Phan img lod 1 E. Phan img Seliwanoft 48... ding 48 phn bigt dong chite cetose vi aldose. 49... ding é phn biat during MS va DS | 50... - ding dé phn bit duémg SC va 6C. 51. Sphingozin tham gia thinh phin céc chét sau diy NGOAI TRU: I A Lecithin B.Gangliozid ——_C, Ceramid D.Cerebrozid _E. Sphingomyetin or i}52. Trong cbng thie cia ADP dui diy, 4 tin két ddn ky higu tir A dén D. Lin két nto su ning lugng ? moO o> o-O-O) z Ki $53, Glucose tham gia vio thinh phn cfu tgo cdc cht sau ddy NGOAI TRU: A-Maltose —B,Glycogen -C, Mannose‘. Lactose E, Sucrose 54. Tép hop dung ndo sau day khéng o6 tinh kh: ‘A. Maltose ~ Lactose BB. Maltose ~ Saccharose CC. Glucose - Mannose D. Glycogen ~ Saccharose E.Glycogen— Lactose Dya vito céc 36 ligu sau aé tré lei cdc edu hai tit $5 din 57: t CHO A HO HO HCOH CH2OH é HO | HOCH HOBH Oo | HOCH | HCOH HOCH HOGH HObH HCOH ie oe HOCH HCOH ee HCOH a HOH HCOH CHOH CHOH HoH CHZOH_=—CHzOH A B c D E 58. Glucose 56. Fructose 57. Mannose 2‘58. Thy phn sucrose stg ra A.Chie6 glucose B. Glucose va Mannose - ‘C. Mannose vi Fructose D. Fructose vi Ribose EFFructse va Glucose 59, Glycogen dng vit chia: ‘A. Cae dom vj Inulin B. Cc dom vj Fructose C. Cac dom vi Glucose D. Céc don vj Ribose E. Che don vi Glucose-1-P (60. MS chim wu thé trong méu li A.D-Fructose B.D-Mannose C.D-Giucose D. Sorbitol E.DL-Glucose 61. Cng thie dung nto sa diy: HOCH, Hook, ‘A. Lactose (dang 0) B. Lactose (dang B) C.Sacarose (ang 8) D. Maltose (dang ) E. Maltose (dang B) HOCH, ee oe Ar aon eo fee Pao 63, Chit ndo sau diy xem i chun vang rong thm di chit ning le elu thn A. Glucose Blnulin Casula D.Dextin E.Cystatin65, Phan trndo sau dy 6 chit duimg fructose: A Dextrin B Tinh bot Inulin D. Insulin E. Glycogen 66. Cie duiong sau dy c6 tinh Kit NGOAL TRU: A. Glucose B. Fructose Lactose D. Suerose E, Maltose 67. Didu no sau dying Lindi védabng lactose: ‘A. Cé bib gan B. Trong thin pin lu yo o lactase . Kh 6 tin Ke DiLigheld dpe co Tham gia did de dng hyét 68. Chit ndo sau day 06 9 nhét cao, o6 thé ding 4é thay thé huyét tuong: A. Dextrin: B. Insulin. C. Ghose D. Heparin E Inulin 69. Chon es ding: ‘A. Fructos It dg 6C mang che ceton _ ‘B. Galactose cé thé diing dé thay thé huyét twong trong m¢t s6 trudmg hop Ribose iu ong ADNWAARN D. Insulin Ia chit diing dé thim do chite aang Joc city thin E, Mannose la duomg SC 70. Dibunio sau diy KHONG DUNG khi ndivé glycogen: A. Glucid dy tr cba dg vit: B, Glucd dtr ci tive vit ©. Cémbitu 6 ga va co D. Kong 6 i kt E. Trong phan tir 6 lgn két 1-4 vi 1-6 | 71, Dusimg nao sau dy xudt hiéa trong nus tigu 6 phy not gin ngay sin: A. Glucose B, Galactose C. Fructose t D. Lactose Sucrose 72. Bibu nto sau day KHONG DUNG khi ndi vé glycogen: ‘A. Cé nhitu trong gan B. Gém todn during don glucose tgo thin C. Thanh phiin edu tao 6 lign két 1-4 1D. Thanh phén cds tgo o6 ign két 1-6 E, Cé miu tim 48 khi tde dung véi fod 73. Chon y ding: ‘A. Glycogen I gluco tin kt B, Tin bgt Ia glucid dy tr cia ng vat C. Cellulose bi thiy phén bai 8 - amylase . Dung lactose c& ngutng bi tit 6 thén khodng 210 mg% I E- Insulin I chun ving trong thim d® bé s6 loc eu thnCHUONG 2 HOA HOC LIPID 1 Lipid tn tong A.Nuée B, Dung mi kg phin eye C. Dung dich dém trong nurée ‘D, Dung dich acid E, Dung dich NaCl 2. Thanh phin edu tgo cla m®t lipid o6 thé chi gm c6: A. Glycerol vi cholamin BB. 1 acid béo va I alcolc6 tong Iugng phn tt ca0 C.Laleol vi acid phosphoric D1 aleol va 1 acid acetic E-Khéng ggi nto 6 tén I ding 5, Acid béo vi acid btm o6 o6 Age diém sau: 1. C6 thé os carbon chin hoe le 2. C6 thé 06 nhbm NH 3. Cé thé c6 mgch thing hofe vong 4.6 1 nhém carboxyl 5.Cé thé c6 nih hod king e6 nn Choe hp ine 5 pone foe 3 4, 4 5 4,5 4, Lipid 06 nhiing chitc nang sau, NGOAI TRU: ‘A. Tham gia lu tne ming B. Dy tri nang ugng CVinchiyen Chia thing tn dean E. Bao vé co thé. 5. Tép hop nio sau diy chi gim cdc lipid thdy phn duge: A. Glycerd, acid linolei, cholesterol este B. Lecithin, acid palmitic, vitamin E C. Cholesterol, trpen, steridD. Tripalmitin, sphingomyelin va cholesterid E. Vitamin A, vitamin D, cephalin 6. Tap hap no sau dy chi gdm acid béo bo hoe: ‘A. Acid oleic, acid palmitic, acid srachidonic B. Acid stearic, aid linoleic, acid propionic C. Acid buy, acid oli, acid linolenic D. Acid stearic, acid palmitic, acid butyric E Acid palmitic, acid inolenic, acd stearic 7. Tip hgp no chi gm cd tip dom gn: ‘A. Monoglyceri, ceri, cepalin B.Diglyesi, sp, teri . Lecithin, tilyceri, cholesterol ese D. Cholesterol, mudi mat, cerebrozid E. Sula, sphingomyelin, acid palmitic 8. Nhém mio sau dy chi ebm cic lipid e6 chi acid phosphoric: ‘A. Cephalin, sein phosphatid,cerebrozid B. Lecithin, tr, cererozid : Lecithin, sphingomyelin, suai D. Lecithin, cephain, sphingomyelin E_ Khdng nhm ndotén li ing 9. Che elu tie no sau dy i ing ‘A. Acid phosphatic: diglyceri,phosphat B.Cephalin:dglyerd,phospat, tbanolamin . Tristan: lycero, 3 aid steaie D. Sphingomyelin:sphingozin, acd bo, phospbat, colin Tat ddu ding 10, Cong thie nay 1: "HOH HOH on CH,—o—P =0 Son ‘A. Acid glycerophosphoric B. Serin phophatid . Acid phosphatidic 1. Phosphoglyceradehyd E. Cephalin11. Thanh phan cla cephalin gdm c6: ‘A Acid phosphatic, erin B. Glycerol, acid béo, HPO cholin CC. Acid «-glycerophosphatic, cholin D. Acid phosphotidic, cholamin . Rhing phi ee thioh pn ké én 12, Thin ph ca ein gm: ‘A Acid phosphatidic, 2 acid béo, colin B, Glycerol, 2 acid béo,cholin C. Acid wiycerophosphoric, cholanin D. Acid phosphatidic, olin E, Cie goiy trén déu sai 13, Lecithin e6 mt trong abiing de dim sa: A. Tép trung nhiéu @ 10 chite md tgo nén m6 du tra 'B. Thin phi gm c6 glyeerl, HsPO,,cholin . Bing vai ur chong i dong ma 6 gan 1. King bi thiy phn trong mdi trong kiém E,Trong thin phin king e6 acid béo 14, Teipalritin c6 mot trong ede dc diém sau ‘A. DE hba tan trong aude B, Trong thin phin c6 cholesterol C6 nhitu trong gan D.Lamtglycerid thud E, Lambe lot lipid tp 15, Chit ndo sau day trong thanh phiin ¢6 cholin: A Ceri B. Cerebrozid C. Sphingomyetin D.Cephalin E. Serinphosphatid 16. Thin pn cia sphigomyetin gdm: ‘A. Sphingozin, cid béo, H:PO,, galactose B, Glycerol, acid béo, HPO, galactose . Glyeerol, HP, acid béo, chain D. Sphingozin, HPO, colin, acid béo EE. Sphingozin, acid béo, galactose 17. Tép hgp ndo sau day gbm nhimg chit rong thinh phinc6 sphingozin: ‘A. Setin phosphatid va steridB, Cerebrozid va sphingomyelin .Cerid vi cephalin D. Sphingomyelin va cerid EE. Cerebrozid va serin posphatid 18, Thanh phn cha cerebrozid gdm e6: ‘A. Glycerol, acid bdo, HyPOs, galactose B.Sphingozin, acid béo, galactose . Sphingozin, acid béo, colin 1. Sphingozin, acid béo, HsPO. galactose . Cie got 9 tin dd sai 19. Aci linolenic Ia acid béo o8: ‘A. 16C vi itn ktkép B, 18C va 3 lidn két kep CC va king it kt kép D.18C vil lien keep E 18C vi2 len kétkep 20. Cholesterol c6 mt trong ning dc diém nao sau diy ‘A. Cé cdg thie chung li CxHuOr B.C62 phe methyl 6 Cio va Cis €.€62 vbag 6 enh v2 ving 5 canh 1. C6 mt chi raga 6 Cy E, cb mot in ket kép Cus 21. Cl no seu dy Kg pit mt phospelpis ‘A. Cerebrozid B. Plasmalogen CC. Sphingomyelin D. Cephalin E Lecithin 2, XA phiong li ‘A. Chat tao nén 9 cing cia nude B. Céc chat tly mang dign tich am C. Magi cin acid béo 1D. Chit dupe tg tinh dothiy phn cc ydrat carbon mach di . Chit lm tng ste cing bé mat 23, Chit béotrung tinh i A. Triglyerid B. Diglycerid €. MonoglyceridD. Cée cblt béo khéng xa phong hide E. Acid phosphoric 24, Thanh phn cia sulfatid ghm c6: ‘A. Sphingozin, HPO, acid bo, cholin B, Sphingozin, HsPO,,cholin CC. Sphingczin, acid béo, galactose D. Sphingozin ci bo, galactose, H:SO, E.Sphingozin, galactose, glucose, HeSO, 25. Cong tite sau dy Ta CH SH— (CH,):— COOH HO. OH ‘A.Cholesterol B. Acid cholic . Acid deoxychotic . Acid chenodeoxy cholic E. Acid lthocholic 26. Ci chit duéi day déu la din xuit cia cholesterol NGOAI TRU: A. Acid mat B. Hormon vé thvong than . Vitamin D .Honmon sinh dye E.Sphingomyelin 27. Acid béo bao hoa mach dai: ‘A. Chita nbidw lign két este B, C6 nfi d8i 8 Coo C. C6 88 carbon lé 1. Bidm néng chay gidm theo 49 dii cus chudi EE, Biém s6i ting theo d@ dai cua chudi ‘28. Chi sé xa phing ding dé xc dinh: ‘A.S6 gam chit béo B Sb gam KOH C. Sb pint acid bo tham gia phn ing 20D. Phin tt lugng trung binh eda cfc acid béo EE. S6 gam glycerol to thank 29. Cong thie ny i - 1H,OOCR; HOCH IH CHO - OH A. Seri phosphatid B. Glycerophospbory|cholin C. Giyceraldehya D.Lysolecithin E,Cepbalin 30. Cong tite may ‘A. Acid cholic B, Hormon sinh dye ©. Cholesterol . Hormon vé thugng thin E. Vitemin Dz 31. Lipoprotein no sau dy twong mg véi Plipoprotein trong ky thudtdign di ADL B.Chylomiceron VLDL, D.LDL E. Chit ke 32. Lipoprotein nio sau dy cngubn ge tut: ‘A. Cylomicron aB.VLDL CLDL D.HDL E.AvaB déu ding 33, Thanh phd lipid no sau day o6 nhiéu trong LDL: ‘A Triglyeeria B. Cholesterol . Phospholipid D. Acid béo ti do E, Sphingomyelin 34, Vai td ota lecithin vi phospholipid trong eu thé A, Cung edp ning lugng B. Dy tt lipid . Nguyén it tye tiéptbug hyp cholesterol . Tham gia cd to ming va vin chuyén mo ti gan dén cfc 18 che E.Clo goig déusai 35. Chon et ding: ‘A. Phospholipid tan bh ht trong dung mai cht bo kd cd aceton B Ly ich phospholipid tt alt bing hin hop cloroforn vi muse C.Bo e6 tinh phn eye nn phospholipid cd kh nog to thin nd tuong ben trong nude. " . Lecithin a nguén cung cp acid phosphoric dé to tf bo moi E. King cfu ndo ing. 36, Chon ctu SAL: ‘A Dipalmiy lesthin lim cho mang phbikhOng bi di ai B. Cephaln 6 vai tr trong sy dng miu | C Phosphatdy inositol diphosphate vai tr trong chuyén hoa phospho D.CA3 cluteén déu si E. Ch efu tren du ding 137. Phosphatid lt nhing chit: ‘A. Luén chit nitrogen ty do 'B. Ddn xutt cia acid phosphatidic CC. Khéng xa phong héa . Luba chit acid phosphoric ty do E. Din xuit cia acid cholanic 38, Hydrogen hia acid inoleic chor sn ph: ‘A. Acid linolenic 2B. Acid paimie C. Acid 9,10-dihydroxystearic 2D. Acid palmitoleic E. Acid stearic 39. Tap hgp nao sau day chi gm acid béo edn thiét: 1. Acid oleic viscid palmitic 2 Acid linoleic vi acid arachidonic 3. Acid linoleic vt ai linolenic 4, Acid arachidonic v acid tere 5, Acid linolenic va aid butyric (Chon pha ding ‘Ald B23 24 D.25 Bas 40. Cholesterol shng fe 1. Limit pyle! 2, La métaleol béc 2 3. C6 mot lién két kép gitta Cs 4. La motlipid kp ta Cag 4. Lami pid dom ih thy pi ge 5. C6 cng the cg i CxHls0 ‘Hay chon tip hop ding: 41. Glycerid 1. Liste ci acid béo vi glycerol 2 Glycerd ng vt chia nh acid bg khdng no 3. Tit ce loa lycerid u khdng tan trong made 44 King miu, mii, vi, nd 6 i do ed cht Khe tn vio 5.06 kh ning tham gia pin img xi png hoa, Chon tp hap ding “42. Ké ten 3 loi tipi thud: re 2BB: c: 43. Neu tn 4 Logi lipid khong thiy phn duge: Ao Bs. cm D: 4, Ligt ke 5 ogi phosphatd: nuoRPe 45. KA 5 logi chit e6 hogt tinh sinh hoc quan trong mA cholesterol la tién chét tgo nén 46, Ké tan ci acid béo thiét yéu: re Bs... c 47. Vict chit sb vo cb ciel thich hop: A Trigheerid 2B. Teipalmiin C.Lecithin D. Acid phosphatic E.Cephalin 1. Acid phosphatidic, colin 2 Glycerol, 3 acid béo 3, Glycerol, 3 acid palmitic 4. Diglycerid, phosphat,ethanlamin 5. Diglycerid, phosphat 48. Vit cde cht sd vio trude cd chit ei thich hop” A. Acid cholic B. Acid deoxy cholic . Acid chenodeoxycholie49. 50, 31 Te 22... 33, 54 “55, 56. D. Acid lithochotie 1. Acid cholanic o6 nhém OH & C3 2. Acid cholanic o6 nhm OH 6 C3,C; 3. Acid cholanic o6 nhém OH &C3,Ci2 4. Acid cholanic e6 nhém OH & C3.C3.C Vikteée cht 6 vio trube ce chit ci tuong img ‘A. Acid bo trang tin B. Phosphatid| C. Cerebrozid D. Sip E.Terpen 1. Thy phn on ton thu ug 3 phn tr acid béo va mat pnt glycerol 2 Acid Bo tao lia kt v6 aleol be cao 5. Chia cc dom vi gig isopren 4. Cn dugegoi I galactoipid 5. Chia cholinhofeethanolamin hoe sein va acid phosphatic ‘Aci palmitic cbn 6 thé théng Ia acd octadesanoic vin 18 mt acid bo cd 16 carbon: ‘A.2 vd dbu ding vi v8 2 gi thich cho vé 1 B.2 vé du ding vi vé 2 kh gi thich cho v8 1 C. VEL ing, v2 sai D.VE1 sai, v8 2 ding E.Ch2védius PPhosphatidy| serin la 1 loai lipid tap vi trong cd tgo phn ti, serin tao lign két este vi acid béo ‘A.2 vb dbu ing va v8 2 git thich cho vé 1 ‘B.2 vé ddu ding va vé 2 khdg gid thich duge cho vé 1 C.VEI ding, v8 2 sai D.VE 1 sai, vé2 ding E.CA2 vé du sai eft 52 dén 56: chon mbt trong cdc én got cud dy cing wit céng thie cia méi chdt Cholin Phosphatidylserin -Bthanolamin Lecithin LSerin 3A: HO—CH,—CH,—N's=(CHs); B; H,COOCR D: — H,COOCR R'COOCH H,C—O— P—OCH,CH,N' = (CH); c Hoc NH; COOH “Tir cu 57 bn cd 60: Tr lt ode edu sou Bing ech sit ung ce ie Khda chi ei: Chon A néu a én hom b Chon B nda ahd bon Cha Cnéu vib gin hog bing nha 57-1. Chiu di chi te acid arachidonic 'b. Chidu di chuBi cs acid linolenic 58. DG bi hos ca acid linoleic DQ io hda cia acid ole 59. Him hug glycerol ei lecithin +, Ham tugng glycerol ci cephlin 60. a. Tinh hoa tan cia chit béo trong dung méi Khing phn cye ». Tinh hda tan cia chit béo trong durie, mdi phn eye61, Acid linoleic aid bdo ‘A. 16C vi liém kt kp BRC va3 len kt ep, 186 vaikhing 6 ln ket hep D.18C vit ign kt kep E. 18C va2 lign két kép 62. Ké2 tn acid béo trong ho «3 clin thiét cho qua trinh phat trib 18 bio nko othe ky lu ca gus tinh sinh tng 6 te em. 63. DHA ti ‘A. Acid lupanodnie B. Acid boc 6 lien két 6; C. Acid cervonie D. Aid bo 5 liga kd E. Ca 2 cfu A Bdéu ding 64, DHA: 1. DHA Ii acid docosapentaenoic thu ho @3 2. DHA la acid béo khiing no ¢6 20C chita 6 lign két d6i, 3. DHA Ia acid béo thue a3 clin thiét cho qué trinh phéttrién tf bio no & thbi kj du cia qua tinh sinh tring tr em, 4, DHA Id acid béo khong no 06 22C chit 5 tin két di 5. DHA liacid cervonic (Chon tip hop ang: AL room 65. Acid nao sau diy a tién chit cia prostaglandin, thromboxan,levcotien: ‘A. Acid deoxyeholic B. Acid eicosapentaenoic . C Acid arachidonic . Acid docosahexaenoic E. Acid taurocholic 66. Chon céu ding: ‘A. Sulfa o6 nbidu 6 dng vit, din xt cia sphingophosphatid 'B. Khi thiy phn cerbrosid sé cho ra sphingosn, acid bé, acid phosphoric v8 slcose ; C. Trong efng thite céu tgo cita gangliosid c6 chira dutmg fructose D Spingonysin ci cha spigot, acid bo, cd phosphricvchlin E, Tat c& cde edu trén déu ding a67. Chit ndo sau dy Khong phai la steroid: ‘A. Estrogen B. Glycocholat C.Cholesterid D. Lanosterol E. Corticoid 68. Lipoprotein ndo seu déy tuong img véi lipoprotein trong k¥ thug dign di AHDL B. Chylomicron VLDL D.LDL E, Chit kn 69, Lipoprotein ndo sau dy twong img véi LDL trong kp thud! sigu ly tim: A. Chylomicron B.pre- BLP CLP D.a-LP E. Chit ke 70. Lipoprotein ndo sau ddy trong img véi VLDL trong ky thugtsiu ly td: ‘A. Chylomicron i B. pre- BLP. C.BLP DaLP E. Chit kine 71. Lipoprotein ndo sau dy tyong img vi HDL trong kj thuftsiu ly tm: ‘A. Chylomicron B. pre- BLP CpLP D.o-LP . | E. Chit kh 72, Apolipoprotein ndo sau day c6 trong VLDL vi LDL: A. Apoadl B ApoAtI C. ApoB-48 } . ApoB-100 j E.ApoD 73. Lipopeptein gb cd shang oi no sau Ay: A. Chylomicron, VLDL -B. Cholesterol, triglycerid C.HDL, LDL D.AVAB ding EAvaC ding 74 Lipoprptein gdm o6 nhing log nao sau day: A. Chylomicron,o-LP B. Cholesterol, ApOAT C.ALP, pre-f-LP D.AvaC ding E.A,BvaC ding 75. Losi lpoprptein ndo sau dy van chuyén cholesterol du thi tr m ngogi bién vé gan: AHDL B. Chylomieron C.VLDL D.LDL E hie 76, Vai tr cha apoprotein: ‘A.On din ew tri eta lipoprptein B. Git lipopepein phn tn rong mau (Chin din thy th mang t bia D. Giip van chuyén lipid trong mau E, Tit céc clu én Adu ding 71. Phospholipid c6 nhiéu trong: AHDL B.Chylomicron C.VLDL D.LDL EDL 78. Cholesterol c6 nhiéu trong: AHDL B.Chylomicron C.VLDL D.LDL EDL 79. Ceramid 6 trong thinh phin cdu tgo ciia nhém chit: A. Sphingolipid B. Phospatid| . Triglycerid »D.Cerid B. Phospholipid 80, Sphingomnyelin 6 edu tric tong ty edu tric trong cla cht nto sau diy: 30 A. Cerebrozid 'B. Phosphatidylcholin Cr. , Acid lithocholie EE, Tit cd cde cfu trén déu saiCHUONG 3 HOA HOC ACID AMIN VA PROTEIN ‘Mgt protein dupe goi li bin tinh Ki A. Dupe dua vé pH ding dign, B. Clu tic be {if 1V bdo fn, C. Dirge bio quin 20°C. 1. Duge dé trong ti anh 0°C tong 2 git E. Bug dua vio bing ti tong 2 gi CCng thie ny A His SH eae 6 otha coe D. Tr. # E, Peo Mét protein c tl bik a bi mobi rang in e6 ng cao. Nguyén anno dh itn protin ‘A. Do protein bj ign tin, B. Do mit lgp do nue. ; C. Do sy trung hoa dign ti ic tiéu phan protein, D. Do mit lop do nude: tiéw; protein bj trung hoa vé dién, E. Khéng céu tré loi nao 6 trén la ging. k fc sh no sau dy the oi protein si 1. Hinh soi di, hit din hom dg kin hing te in, 2. Kh tan ong nue van wong dng dich musi loin. 3. Thuimg ci tgo bai lién két disulfid, 4. tinh ben vg v iy co, ‘5. Thude nhém che cho va la yéu t8 co bin cite mé ign két, Chon tp hop dling nhdt: "ALR B23 © unas D 236s E, Tha ce etn rn bu ding, ‘Acid amin e cha nm imin A. Vali, B. Prolin, ©. Tyrosin, 31D. Tryptophan, E, Cyatin coo ng thie ny HaN—G—-H Abs. CH, B Lew te . ©. Val. SB D. An Raa CH “CH; Chit no sau dy c6 bin eh 1 protein: A. Carbohydr B. Vitanin, C. Teiglyeri. D. Enzym, E. Khdng phi cic chit wén. ‘Trong phuong php dig di protein, néu pH dung dich dm nho hon pi ding dign th protein sé ‘A, Di chuyén vey B. hing di chayén C. Dichuyén vé eve duong, DT E, Tyo dang ung ev. ‘Trong phép dign di, cdc acid amin ndo c6 pH ding din nh hon pH dung dich dm thi ching 8: A Tin, B. Di chuyén vé eye am. C. Di chuyén vé eye duromg. D. Khéng di chuyén, E, Teo dang hong ove 10. Acid amin nio sau diy 06 chim nhém ~SH: n, 32 A. Cystein, B. Treonin, © Cystin, D. Histin, E. Methionin. Cg thie nayD. Methionin. E. Treonin. 12, Acid amin no sau day khong cé tinh chét quang host A. Tre, B Me. ©. Gly. D: Val E. His, 13, Protein no sau day trong phan ti chia HPO. A. Siderophylin, B, Seruloplasmin. 14, C62 protein cin duge tich bing dién di cé pH lin luge la 4 va 6. Hay chon mat dung dich o6 pH ndo sau iy 48 tich duge tt nhit2 protein dé: 15, Acid amin nao ¢6 chita 1 cd disulfid: A. Cystein. B Lysin ©. cystin, D. Methionin 16. Keratin li: A. Globulin B. Tripepti. ©. Protein gi D. Histon, E. Protein clu, 17. Phan ing Millon li A. Phin ting cho béi tit ca acid amin, B, Phan img cho bai protein chia tryptophan. C. Phun mg cho bai protein cé nt SH tr do D. Phan ing cho bei protein cargo, E, Phin mg cho bi protein chia ton, 318, Globulin va albumin due coil: A, Protein si 1B, Protein bign tinh. . Protein wp. D. Protein thuin. . Protein de bin, 19, Hy chan tip hyp ding cho ning cus dy: 1. Pin ing biuret dong nh v6i ce ci ain 2. Glutathion bao gbm aid gltami, plycin va histin 3. Dipeptid va protein luda luén cho phan img biuret ém tinh. 4 “Tipp vi protein lu un cho phn mg biuret dong tinh. 20. Chon cfu SAI: . Protein bi bién tinh dé téu hba hon. D, Protein dang & dang hinh céu khi bién tinh sé dubi thing, céc ném ue nude sf chia ra ngoli E. Enzym ribonuclease ki dun néng vi trong méi trudng acid né sé bi bién tin, ru 8 nhigt dO thutmg va pH = 76 sé é ai dang ban dau. 21. Céng thie ny coo A. Acid glutamic. S B. Giuamin. ‘Albumin 6 tinh chét no sau diy: A Laproein si BB, Buge thie tich ahanh so voi mui C. Bi két ia boi acid trichloacetc 30%. D. Vig bén trong mdi truimg HySO, dim dc, EE, KEL a kh tc dung véi mudi CuSQy 23, Acid glutamic c6 pk ~ 2,2; pKa = 4,04; pK = 9,7, (Chon tp hop cau ding: 1. “pHi cba acid glutamic I 3,12 4 2 ESE RSIE SEENON2. pHi cia acid glutamic 1a 5,95, 3. pHi cia acid glutamic la 6,87, 4 Khi cho chay dién di vi pH dung dich dm 1 3.9, acid glutamic sai chayén v8 catod (-). 5. Khi cho chay din di vi pl dung dich fun 39, acid glutamic Edi chuydn vb anod (). " 1,5. Fone pee 24, Mot protein thé bj két nha boi hign twong diém ich hay salting out, nguyén nbn la ao: ‘A. Thay died te protein, B. Mit lop éo nude. C. Trung hod dign tch cia téu phan protein D. Do mit l6p 4o nude song song véi trang hod dign tich cia céc tiéu phin protein, E. Cie cau ttn dba si 25, M@t acd amin chit sul lis A. Chondrsitn sult B. Tryptophan . Suliypyruie D. Homoeystein E. Ghiabion id 26. Chon cfu SA: ‘A. Opll ding din cic acd amin trang hb vé da B, Protein & tia rong mdi rung ed pH = pH, . CC. rong pep dign di, ngudi ta chon pH cha dung dich dm gin bing pH ding ign eta cde acid amin, D. Tong mdi tring dung dich mn c6 placid so vi pH, cb cid amin thi amin 6 s8tch ign dong E. OpH ding ig, acd amin thing di chuyén dui anh hung cia ign ving 27. Nhimg chit nao sau day thube protein te: 1. Glucoprotein 2. Albumin Hay tr: 6 tap hop nd ls ching: A123, 828 30. 3 36 Chon tap hgp ding: |. Tt ca cde nhém amin trong cfc phaa tir. Ce ci amin uo th phi ng vGinnhydvin go phi cht mau xan im (Cc ci amin pining vi niin go ra NH va aid be ‘Thuy plating phn potin tor cde aed amin va poypept. Nhém carboxyl cia cde acid amin cé thé bién di thanh céc din xuit nbu ester, id amin phan ig véi acid nitric tora trogen [Ning acid amin ndo sau ddy thuge nh6rm acid amin khéng. phi eye: ‘Tryptophan, valn,leucin lanin, B, Glycia, alan, axginin, wyptophan . Glyei, isi, iecin, valin . Leucin, acid aspartic, alanin lysin E, Tita cdc cau trén déu sai nitg cht no sau dy the lop protein tn 1. Casein 2. Fibrinogen 3. Fein 4. Collagen 5. Choropaylt ty chon dp hep ding 423 1 2, ca 1, moo ‘Tap hp ni sau dy chi gh ch acid amin trang tn A. Glyein, alanin, acid aspartic, tyrosin. B. Alanin, valin, lysin, leuein. . Alani, ei gta, vatinthreoin D, Methionin,isceucn, eon, serin E. Osten acid aspartic, vain, thconin 22 33 M 38 a32, Nh no sau dy chi gbm ed acid amin mech thing ‘A Acid aspartic, elycin, vali tyrosin B. Alana, elycin,threonin, histgin, . Alani, acid asparic,argiin, thrnin D. Threoin, leucin,ryptopha, methionn. , Valin, phenylalanin, even, ein 33, Nh nto sau dy chi gm cdc acid amin dj vong ‘A. Pro, His, Hypro, Try. B. ‘Try, Tyr, His, Lys C. Phe, His, Tr E. Pro, Phe, His, Hypro. 34, Ph ig ninydn dng de dns ‘A. Aci ain chia nim SH B. Lia két peptid. ©. Acidamin, D. Cholesterol E. Lién két glucosid. 35. Clu rie be I tia protein ie A. Strxoin din 64ncia chi plyncleoti B. Sioa cut gdp kc eta hod polypepti. . CC. Sixoin du in ci chub plypeptid do lin két hydro guy inh D. Do cée lin két mubi va lién két disulfid quyét dinh. E, Che eu tn du si, 36, Céu tric ba IV cia hemoglobin la: ‘A Do itn kt pepidquyét inh B, Do lin dt disuld quyét dh _, C. Do chub polypeptide clu trie bc 3 sp xéptuong MB vi nau. D. Do sy xoain cugn cia chubi polypeptid. E. Do sy xodin déu dan cita 2 chudi polynucleotid. 37. Protein e6 thé bj bién tinh bai: A. Che chit ki B. Cle bic x9 cd ning lug cao. Nit to, , Clcion kim lon nig. E, Thkea abv aing 138, Tit a protein: 1, Déu chim carbon, hydrogen, oxygen vi nitrogen. Ey2. Chin 14-20% nvogen 3 Cot jeu) pa tor acd amin ty do v4 polypepi. 4 “Theo qui wée, du chita acid amin tha nihit la du N tn. Chom tip hop diing: Ah8 i B ©2, D. Chi ed 4 ding. E, Tétcé4 truong hop trén déu ding. 39, Acid amin ndo sau diy i acid amin kiém: A. Tre B Lys ©. Val D. le. E. Met 40. Ninhydrin la chit duge ding trong phin img din tik: A. Glucose, B. Acid amin C. 17 Alpha ketosteroid D. Acid béo, E, Polyssocharid. 41. Phin ng birt ing ‘A, Tim tryptophan. B. Tim pentose C. Xie dah x 6 mate acid ain. D, Dinh yng cholesterol. , Xie dnh en kt pep 42. Ky higu gi: D-ysin +135 phi oe thé mo ing nd ‘A, Chit idm Iysin, B, Lam igch nh sing phin oye 1 g6c 13,5. C. Chit hou triénIysin, 1D. Chat hia tridn D-lysin lam Ifch dn sing phin eve qua phi 1 g6e 13,5°. E, Tit cf eich dge tén du si Tired 43» 46 gdm 2 yé, lien he v6i nhaw bing chit bi ‘A. Vé1 ding, vé 2 ding va ve 2 gi thichcho v8 1. 'B. Vell ding, vé2 ding nhung vé 2 khéng gid thich cho v8 1 C. Vé1 ding, vé2 si D. VE sa, vé2 ding E. Ch2vé dbus 38 | t| | | 43. Céc acid amin o6 tinh lung tinh bt i 481 Khi ching c& 2-nhém carboxyl ofc 2 ‘nhom amin. “4. M6t acid amin o6 thé due phéthign bing phan img ninhydrin béi vl ninhydrin chi ‘te dng v6i acid amin ty do, 45. Tai diém ding dién pHi, cdc acid amin king di chuydn trong din tring bi vi cbc seid amin rung oa v8 dig 446. Nhimg peptid chia acid amin vong khng e6 host tinh sinh hge béi vi né dng bao ‘gi chia nhimg nhém ion hod duge Bién ede chit ei chm orl ding ct ctu hd 47-51 ‘A. Myoglobin B. B-Alanin. C. S-Hydroxylysin, D. Monoiodo-yrosin. E. y-Aminobutyrc acid (GABA), 47. Tién chit cha acid pantothenic. 48. Chit c6 cfu tri be I im thy trong protein co ca loa cd voi 49. Chi duge tim thy trong collagen, ‘50. Cé host tinh kich thich t6 trong tuyén gidp trang. 51, Tim thdy 6 nfo va agian chét cia lung thn kin, Din cdc chi ci chon tr Idi ding cde edu hdl 52-56: ‘A. Phan img Sakaguchi, B. Phan img Millon, . Phin img Adamkewich. D. Phan tg tgo sulfur chi . Phan img Biuret 52. Buge ding thir nghiém tryptophan c6 trong cfc protein 53. Phin mg dug tgo ra boi protein chica arginin, ‘54, Buge tgora bai protein chia tyrosin. 155. Buge tao ra bai protein chia nhém SH ty do, 56, Baye ding xée din polypeptid va protein. 957. Chon cdu SAI vé sy bién tinh ca protein: ‘A. Khi dua pH mai trang vé pH ding dign, protein s8 bj bién tinh. 3. Mi pond oli td inh Ki cut We 2,3, 4d io. C. C62 Jogi: bién tinh thugin nghjch va bién tinh khdng thuén nghich. D. Cie the nhan cé thé gy bién tinh protein: acid, base, tia X,. Cle cd amin vi ppt ong Ehag id ak 58. Khi pH ding dign (pH) cls acid amin lon hon pH dung dich dm: ‘A. Acid amin tia, . B. Trong di uum, acid amin di chuyénvéphia cue dm. CC. Acid amin hogt dng abu mgt acid. D, ‘Trong di tubo, acid amin khbng di cuyén EE. Acid amin chi tn ti dang cation 59, Chon céu SAI: ‘A. Clu tric bée If cia protein la sy xodn déu dn cia chubi polypepid, do lién {et hydro quyét dh, . B. Clu tric bfe IM cia protein la sy xoin vi gp khiic cia chubi polypeptid, do ign két disulfi quyét dnd CC. Clu tri bie TV cit hemoglobin Id do 4 chubi polypepidcé of tic be IT sp xdp tuong hb véi nhau. D, Lin ké dsulid ding vai td quan trong tong duy tri cdu tie bfe II eta rotin . . Xolin collagen 1a mt dang céu tric bg I eta protein (60. Cae yéu té lam gidm tinh tan eda protein: ‘A. Khinhiét dp tng trong Khoding 0 dén 40°C. 'B. Khi pH m6i trromg cing xa pHi cia protein CC. Néng 48 mudi trung tinh thdp (hign tung salting in). 1D. Céc dung mai alco}, ceton, amonisulfa E, Khong edu nto ding. 61. Acid amin 6 chubi bén kj nude gbm, NGOAL TRU: A. Ala B. Phe. © Lys. D: Mle, E. Tp. (62 Acid amin c6 chubi bén phn cye & pH co thé gdm, NGAI TRU: 40 A, Met B. The C. Ser. D. Glu E, Cys.63. Chit KHONG la acid amin: A. Omit B. Citrulin, C. Glutamat D. Collagen, E. Lysin, 4. Chon tp hop ding: 1. Protein khéng bj téc dung khi thay 48i nhigt 49, pH va bj bic xa tir ngosi. 3 Protein chira céc nhém amin va carboxy! ty do bit nguén tir cée nhém gamma- carbo] cn glitamic acid vce am epailon-amin a sn. Protein thé hign tinh chét cia 1 dung djoh keo khi boa tan trong nude. Prin dpa wm hc amity oc on ei Tinh chat 3c bigt cia cdc acid amin la hiu nbu tit c& ching déu tgo lién két ot 12,3, . 2, 34, 1, 2, mone 65, Acid amin c6 chub ban ich ign dm & pH ca thé Tyr Asp His, Val Arg amin o6 chuéi bén trung hod vé dign & pH co thé gbm, NGOAL TRU: R z 2B moom> Fee moo 2 (67. Acid amin c6 chudi bén phan cue & pHi co thé gm, NGOAI TRU: 41C. Glucagon. D. Gastrin, E, Glycerin 65. Chat cho phan ing biuret duong tinh: ‘Acid amin, “Monosecchasi Diacyl glycerol . Trglyeerd Tetrapept 70. Chit no sau diy KHONG thug protein thuln: Myoglobin. Albumin. Keratin Collagen. Histon, mooe> pooeP ‘Davao cic at lifu sau dé ard 16 ec edu hol ae 71-75. ‘A. Glutathion B. Beta alan, C, Albumin huyét twong. D. Globulin. E. Gramicidin S 71 epi King sn 72 Acid amin 6 nhm -NH4 gn vi carbon 73, Pin ing bret duong tinh: 74, Két ia tong dung dich amonisulft bio hot: 75. Két ta tong dung dich amonisulfat 50% blo hod 76, Ap suit keo trong long mach: ‘A. Lip suit thuj tinh to boi protein. B. Thip hon 6 diu mao tinh mach. C. Cao hon 6 du mao dong mach. . Bing 0 ¢ mao mech, E, Cé ti dyng hit nude vio lng mach, 77. Lin ket ng vai trd quan trong trong cu tric bg Ile protein laf f D. Glycosid. E. Disulfi, 78. Chon cu ding v8 ppt va lien kt pep ‘A. Peptid gm 2 hoe mhidu hm ee acid amin ign kd vi aba ing itn kt 2B. Dé xde dnb in kt peptid ngubi ta ding phi dng mau bret. ©, Cae chat nbu glutathion, glucagon, insulin, bradykinin déu 14 ede pepeit D. Ban chit cis lidn két peptid la lign két amid, E, Tat cd cde clu ttn du ding 79 atin de tim thy aidw nhl tong: A. Melanin. Chondroitin ut Myosin Kentin Collagen. 80, oi pH mdi ring ~ pH ding digo: A Ning 4 acid amin 6 dang ion ling cv dt 1th B. Nong 46 acid amin & dang ion im hole ion duong dat t6i da. CC. Néng 4 ion duong vi in of thé Khe au uy tg lai aid amin D. Acid amin e in an th nt. , Ting ign tic ef on ke 0. moo 484 CHUONG 4 HOA HQC HEMOGLOBIN ‘Trong hem, hai nhéwn thé propionic gin véi nbn prophyrin & ede v tri Al2 B34 ©. 56 D.78 Logi Hb nio sau dy ma 6 chub o6 acid amin & vt sb 614 valin: A HA B. HC c. FRS. D. HOF E. Kh0ng phai Hb nio ké tren Logi Hb nio sau dy 6 chudi B 6 acid amin vj tis 6 1 ys: A HbA B. HC C. HOF D. Hes E. Khéng logi nto ké tren ‘Trong hem, 2 nhém vinyl gin véi nn porphyrin 6 ce vit: Als BS C36 D. 26 E78 (Chon tp hop chi gim céc din xuit chia Fe? 1. HbO, 2. HOCO, 3. HbCO 4. Met 5. Hb A lad B34 © 125 D. 14s E234 | i | | | |6. Din xuit nio cia Hb e6 chia Fe* A. HCO B, HCO: ©. Hb; D. Met E, Khéng dn xudt ndo 6 trén la ding Jy )nban bp say O8y sh ghmo Jogi chromoprotein cb nhém ngosi chit nhin porphyrin Hemoglobin, cytochrom, glycoprotein Hemoglobin, chlorophyll eruloplasmin Chiorophyil, hemoglobin, feritin Hemoglobin cytoehrom, chlorophyll Flavoproten,cytochrom, chlorophyl roo 8, Khi phn ch Hb cia mage aré 10 tui, a thu dug gi tr sau 10% HIF, 90% HbA ‘A, Nag gi ndy nm ong Khong binh thing B. Ning gi tri ny be thzimg 8 ri loan trong shin think choi a Joan tong syhinh thn chub E, Che gi tr Adu King ing 9, Lin kt gta Fe cia hem vi nin imidazole hstidn ci globin én Ket A. Chag hat B, Pb C. Hydro D. Eser E, Giycozid 10. Chon edu SAI: Hl gm 4 dom vi, mi don vm mt chub polypeptide gin vi mgt em ‘Hb két hgp véi oxy va CO Lin hugt tgo oxyHb va carboxyHb qua Fe"’cia hem Sip ony ba Fe cba Hb thin Fe” bién Hb thiah MET Khng cb chia che ning hé hip. HbA 6 globin li a8": Hb kt hap v6i COs to carboxy Hb mo RP 11. Chon céu SAL ‘A. Nadi ta tim Ht tong nue tibu bing cih img dng ti chit enzyme cia Hb B. Hb 6 ding vét o6 vie trong luomg phan tir khong 65.000 CC. Phin ti Hb 6 nguai gbm 4 chub polypepid va 4nhém hem D. Ki Hb bi ony ha s ao thinh Met Khdng 6 kh ning gin oxy B, Khiéing cfu nto sei 4s12. Chon edu SAI khi ndi vé dtc tinh cia porphyrin Ching chin vn pyc Nv ie herby CC eh ning to mul vl cing chia ahi carboxy] (Coking to este icing chin nhim earboxy Ching op che ng ms Cotta bazyéu mone 13. Nhm no sau day chi gdm céc logi chromoprotein chia nhém ngogi khéng phi a sa porphyrin ‘A. Hi, myoglobin, flavoprotein B. Hb, chlorophyl lavoprotein © Chlorophyll, hemocyamin, cyroehrom D. Hemocyamin, frtin, lavoprotein E. Hemocyamin, frit, eytochrom 14. Chon edu ding: > . Hag cfu & ngubi chin khong 25% la Hb, tong ing 15 g dn 16 g tong 100 ml més Hemoglobin i mot lgi protein tap . Tinh thé hematin duge dmg dung tong phip dF xicdinh vEt méu cia dg vet ). HbS la Hb chi yéu cite bénh nbn bi thiéu mau hdng cw hinh bia . Khong cdu ndo ding rp 9p 15. Chon edu SAL: ‘A Tinh thi hemin 6 mau tring, thé dupe tg bing cich dun Hb vi mgt bn top mui NaCl va acid acco . B, HOC la Hb chi yu eda ben nin bj higu méu hg chu hin im CC. Hb bmg oa protein 6 cu ie be D, Tile song Hb a 0.34% E. Khdng no si 16, Chon eau ding: "1 46 ‘A. Hb 6 tin cht cia mt oxydoreductse, ete phi mg chu nim, BB. Hb 6 hog tnh catalase yb, wc tc phn ing: HaO2+ AH — 220+ A CC. Nhu cit ony he af nitt, clot oxy héa Fe eda Hb thinh Fe” to Met Hb theo phuong tinh sau Hb = (MH) D. Hb+COrHbCO E, Khlng cu no ding Chon céu SAI: ‘A: 1 gam HD 6 kh ning gn 1,34 mil oxy B. CO eb i tue wi Fb pap 210 ln oval oxy C. Hb + 02 tgo HbO> la phan img o::ygen héa va thufin nghich ry 2D. Hb cé tinh chit cia mot peroxydase 16 rt we the phin img: 24:0; + H,0 + o; E. Khong edu ndo sai 18. Cle tinh phd cé tong cu teen Hb sp xép theo tit phic tap din ‘A. Pyrol, porphyrin propin, hem, B, Pyrol porphyrin, hem, porphin . Fyrol, porphin, porphyrin, bem D. Porphin, pyrol, porphyrin, hem E) Khbng clu nd ding 19. Chon cdu SAI: ‘A. Hb gm 4 don vi, m&i dom vi gm 1 chub polypeptd gin vi BB. Hb kéthgpv6i oxy vi CO tgo oxy Hb va carboryHb ua sit hai eta hem C. Sw oxy fia Fe cia H thin Fe’ bida Hb thinh Met-Hb king edn cic D E Them singh hip : ). HbA e6 globin la a*s6* trong 46 Fe" cia hem néi véi chudi a ‘hoje B bing lin kt pi trv ann indole hist Hb két hgp véi COs tg0 nén carboHb qua nhém amin ty do cia globin. 20, Chon elu ing 4. Hb ewe dp ham gia vn chy hong 20% tg 38 CO 0 thin B, Hb vin chuyén CO theo 2 con ung tre tgp va gi ip CC. Hb vin chuyén Khong 97% Or ong ma D. Binh thuing, rong miu Mi chiém Khong 1% E. Ciccdutren du ding 21. Chon tip bop ding 1. HDA 66 cutie ay 1H ch yu &ngubi ting thinh 2. HBF 06 eu ric 04s i Heh yu tain . 3. HOS gly bgoh thu miu hdng cu hnh iém do thay di 1 acid amin trang chu 6. 4 Tinh cht quan wong ci Hb lat hgp wi ony la COs qua Fe ei hem 5 Hib dt hop vi CO to carbo, rt ben ving king vin chuyénduge oxy A123, BIBS cus Dip E, Thked tu ding 2. Khi Hb bj oxygen a tgo Mei th ng ob chte ning he hp vi Met Hb king 6 kh nag gin oxy AL VEL ding, vé2 sai B. Vé2 ding, vé 1 sai C. Ch2 vi ding vt v2 gl the ho v1 ”D, Ci2 vé déu ding vi vé 2 khng gi thich cho vé 1 E Ca2vediua 23. Bénh héng edu hink liém, chon cau ding ‘A. Do dt bin gen mia ha chub polypeptid alpha 'B, Do dot bién gen ma hoa 2 chudi polypeptid beta CC Do dt bién gen nf boe I chub alpha va 1 chub bet. gen md ha 2 chu polypepi 24, Dang hemoglobin ndo ult hi du it rong thoi igo pb: AC HDA B. Hbs . HC D. Hb Gower! E. HOF 25. Gen mi ha hub polypepid alpha nim trén nh si thé no: A.NSTI6 B.NST3 ©. NSTIB D. NST 20, E NST? 26, Gen ma héa chubi polypeptid beta nim tén nhiém sic thé nto NST21 NSTX NSTY NST 14 NSTI mooee ‘27. Nhitng yéu t5 no anh hurémg len ai lye ciia hemoglobin di véi oxy: A pH B, Nong 4 CO C. 23-Diphosphoglycerat D. Ciba déu ding E, Ciba déusai 28, Trong bénb ly héng edu hinh bia, chudi polypeptid beta bj dt bién tai vi tri acid amin no sau dy ‘Acid amin th 614 acid glutamic thank lysin ‘Acid amin tht 9 la asparagin thin methionin ‘Acid amin th 13 a uyptophan thin eystein ‘Acid amin thi 6 la acid glutame thinh valin ‘Acid amin tht 21 Ha roABE 4829, Thin phan chinh cia Hb trong héng cdu ngudi tring thanh li Ane B. Ger - CBs D. ab: E. ab 50. Nguyén nhin nao sau dy gy ra béah hdng clu hinh lidm: ‘A. Mit ving promoter ca gen bigw ign chudi beta B, Tang sn xuit protein ea gen mi hia chufi ape C. Tang sin xuit protein cia gen ma ha chudi beta D. Dot bin thay thé nucleosid trén ving gen mi héa beta globin EE, D§t bién mit mocleotid tén ving gen mi ha beta globin | 31, Boh beta-thalassemia thé ning cd thé king o6 iu hig lim sing cho én khi te ‘ge vai thing til do nguyén hin no san dy: (Gen a-globin khong hogt dng cho dén vai thing sau sinh Ting hemoglobin A2 bi tri cho vie mat gen B-lobin (Qué biéu hign ¢-globin bi tnt cho vige mét gen Brglobin Luong oy ci ho tu le mai sind al thidu . Si ehuyén host ng ti alobin sang Blobin khdng hodn tt cho én vai thing su sinh mone ép dng gta oxy va hemoglobin ‘A. Ail gin vi pn ti oxy thi ty eao gp 100 lin so vi ve gin wi oxy du én ea phin hemoglobin, B. Ave gin vi phi tony thi tx thip om 100 tin so vii ue gin wi oxy dtu tién cia phi hemoglobin ; i CC. Chu hinh protein thay 8 theo chidu hung md rg tng kd ning gin vi | ony i D. Civ, C ding E, CiuB,C ding 23. Tie dng kp thd xd r i voi hemoglobin: i A. Chi xdy a nga } B. Lam gidm thiéu sy giao oxy cho md ciia Hb i C. Lim gia tng kh ning gio oxy cho mo cla Hb i D. Chi thly sult hia tae dng niy & myoglobin I , Cie elu én dds 34, Protein dtr oxy cho ea: ~ A. Hemoglobin | B. Albumin ' C. Myoglobin 49D. Elastin E. Collagen 35. Chon cit SAI: 2,3-diphosphoglycerat (2,3-DPG) ‘Buge tim thy tong phn te hemoglobin ki ge ich ating ca 3. Gin di lyre cao voi hemoglobin bao thai so voi hemoglobin 6 ngudi iuimg. think : P Lim gm i lye cla hemoglobin di vi oxy ). Hinh thin lin kt rau vi choi ca hemoglobin ‘Gin véi phiin hem cia phan tit hemoglobin 36. Dang hemoglobin hig dién cha yéu trong bao thai A. HbA 3. HOB. HS HE HOC mpe » moO 37. Phin ti hemoglobin e6 tbng cag... chubi polypeptid trong cu tric bf IV. ppop> 38. Hem tong phn tt hemoglobin: ‘A, Ving xoin trong pin tir hemoglobin B. Chudi polypeptia C. Phin t oxy tong phn ti hemoglobin D. Mt pint ahd Gong phn ti protein E, M@t ving mat phiing nim gitta céc phan ti protein: 39. Cc he thing Khun sau dy gp uy ti Iugng Me-H tong co thé thép di 1% ‘A, NADH dependent methemoglobin reductase B, NADPINADPHE C. Acid ascorbic D, HE thing glutathion Kir E, Cle cdu én déu ding 40, Néu PaO giém din theo tubi, PeCOs sé thay di nr thé ndo ki tub ting len ‘A. Gidm dan theo tubi nhu PO? B. Tang lén theo tudi vi khdng thé thé ra . PaCO, vin king thay 4 thi CO: c6 thé khuéeh tin tt hon Or gp 20a D. A,B,C duding E A,B.Céusai 50CHUONG 5 HOA HQC ACID NUCLEIC 1. Thanh phin cdu tgo cla mt nucleotid gdm cé: ‘A Base ita va dog pentose B. Bas rita va acid phospheric C. Base ito, dung pentose, aid phosphoric D. Base nit va 2 acid phosphoric E, Cle elu én Adu sai 2. Néu thy phn hon ton acid nucleic ta duge céc sin phim theo tit x sau ‘A. Acid nucleic ~ Nucleozid ~ Nucleotid — Base nto — Pentose B. Acid nucleic ~ Nucleotid ~ Nucleozid ~ Base nito -Pentose C. Acid nucleic ~ Nucleoprotein —Nucleotid~ Base nito D. Acid nucleic ~ Base nite ~ Pentose - Nucleotid E Nucleotid - Nucleozid ~ Base nito~ Pentose 3, Trong ee base chin su dy, base nto nd Wg cb dang dng pi actin lca A. Adenin B.Guanin Thymin D. Cytozin Ch elu rin dd si 4. ADN duge cu tgo tr cdc base nito chinh sau diy, NGOAT TRU: A. Adeain B, Cytosin C.Thymin D. Uracil E, Guanin 5.Trong ADN, cip base nitondo sau dy nbi v6i nhau bing ba ign két hydro: ‘A. Adenin vi guanin B. Adenin vi thymin C. Cytosin va guanin 1D. Cytosin vi adenin E. Urcil va thymin 6 Khim cl rk a ADN, Watson vi Crick hi nh: |. Phin tt ADN gli 2 cB polypeptid xan di theo 2 ng ngupe chiéunhau 2. Chase ito ea 2 chub ni vi nha bp lia kt hydro theo guy Tut i base 3. MBi chu ky xodin o6 chiéu dai la 3,4 nm J4, Cle nucleotid nim thing géc vd trye vi eich nhau mgt khoding 3,4 A° 5. Céc base nito nim ngodi xoin di. Hay chon tip hop ding: ‘Als Bas c.12s D.234 5 E134, 7.0 pH=7, dang dng phn nbo sau dy cin adenin chim da sb: AcLectm B.Lacim C2 dang bing shan D.Thted dla sai E.Thted dda ding, 8. ARN vin chuyén (ARN: 1. Chiém ti 12 5% tag tugng ARN 2. Cie bas idan chiém =10% ung 3 base nit cia ARNt 3. 3'tin ing li CCA (chitu 5-3) 406 phn ugg ln at trong cdc ARN 5, Soi polymucleotid cu kc thin hin cht ba Chom tp hep ding: ‘A134 B34 C245 D.235 E135 9, Trong mucleosid, base nito vi dung pentose lién két v6i nhau bing lién két N- lyeosid, in kt ndy age tp ita bat: 'A. CSc ing pentose vi'N9 cia base prin B.C a dong pentose va N9 cia base pyrimidin Cea dung pentose vi.N9 ci base purin D. CI’eta dung pentose viN9 ea base pyrimidin EC ea ing pentose vi N3 cia base prin. 10. Tap hop cdc lign két nao sau diy gp trong du tric cia phan ti ARN: 1. Litn két 2 3-phosphodieste, ign két amid 2. Lign kt N-glycosd, ign kEt est phosphat 3. Lin két pyrophosphat 4, Liga két 3, 5' phosphodiester 5. Lin két hydro, Chon tip hep ding: ALA 2B.245 C345 D234 E. Tit cd céc lidn két trén, ~ U1, Chon c@u SAI: Bie diém cis dutmg ribose la: ‘A. La thinh phin cfu tao cia acid nucleic 'B. Hign dign 6 ARN. ADN €.L&mbt monosaccharide D..G vj ti C2" c6 mang mét nhém -OH E, Tpo lin két phosphoester véi acd phosphoric 6 CS’ 12, Thanh phn cfu tgo cia GPT gim: ‘A. Gusnin, ribose, 2 HsPOs B. Guanosine, ribose, 2 HsPOs C. Guanin, 3 HPO, D. Guanin, deoxyribose, 3 HPO. E, Guanin, ribose, 3H;POs 13, Chit no sau dy khdng phai bese prin: A.Guanin BCafein . Adenin D.Cytosia E. Theophylin 14. Chit nto sau day khong phai a base pyrimiin: A Thymin B.Cytosin C.Uracil D. Guanin E, Somethyleytosin 15, Base nite ndo sau dy 6 nim -CHy trong cng thi: A. Guanin B.Cytosin C Uracil D. Adenin E. Thymin 16. Chat nao sau day 1a mét nucleosid: A. Adenin B.Uridin . Gumnosine monophosphat 3D.ADP E.ATP 17, Chit no sau diy mt nuceoti: ‘A. Guanosin, B. Thymidin C. Deoxy adenosin, D. AMP ving E. Uridin 18. Lién két gitta base nito va pentose trong mot nucleotid ld lién ket A. Phosphodiester B. Phosphodiester C.Hydro D.N-lyeosid E Pepid 19, Chit no sau dy 1a dla ult cba aden: A. AMP ving BAD? Cate D. S-adenosyl methionin E-Titea du ding 20. Chit nio sau dy IA mst dinucleotid A.COP B,OMP ving C. Acid thymidylic D.NAD* E King ct no 21, Dang ne pd bi ola ADN i: A. Xolin dom vong_ Bi Xodn do vong Xin don D. Xolin 481 E, Khéng dang nao trén 22, Phin tir ARNm 6 du 5’ tin cig bing phan ti: ‘A. S-Hydroxy methyl eytidin triphosphat BB. 7-Methyl guanosine triphosphat CC. S-Methyeytidin triphosphat D. 5,6-Dihydrouriin triphosphat E. Tt cf du sai, B, 4, 26, 27 28 29,23. phn ARN nn kt thi bing mim CCA (chit 5'~ 3 dug oi: ‘A. Nin tgp én B. Nha db ma C. Nhanh ToC D.Nkénh D E. Thc du si 24, BD ba dbi ma dupe tm thy o: AARNm, BARNr CARN D. ADN logi B E.ADN loai Z 25. Phin tt ARNt gbm cé: ‘A.3 nin chinh, mt nin phy 1B. 4 nhinh chinb, mt nhén phy CS nhinh chin, mt néoh pa D. 5 nhinh ehinh, khong c6 nhénh phu 4 nhénh chinh, khdng 6 nhénh phy 26, Chit mio sau dy la mot dinucleotid A.NADPY BL AMP ving CADP D. Acid eytidyic E.GTP 27. Thiy phn acid ribonucleic trong mdi truimg acid s& thu duge: A. D-deoxyribose, cytosine, adenin B, D-ribose, thymin, guanin C. D-ribose, cytosine, ural thymin 1D. D-ribose, uracil, adenin, guain, cytosine E. D-deoxyribose, cytosine thymin, adenin, guanin 28. Théng tin di truyén durge chita trong A.ADN BARNm CARN D.ARNr Tht ca déu ding 29. Veit sin ge a ARN ‘A. Tich tit théng tin di truyén 3sB, Mang thing tin tir ADN t6i ribosome . Hin thin ibosome, Ic bg hap protein D, Vén chuyén acid amin dén ribosome 30. Cong thie ny i E. Tit cd déu sai. x of A Cytidin B. Thymidin C.Guania D.Cytosine E, Adenin 131. Phin protein thuimg gap trong nucleoprotein la: ‘A. Albumin va globulin B. Albumin va collagen C. Colagen va histon D. Protamin va histon . Protamin va collagen 32, Chu tne sau bidu thi WN ‘A. Dang phing h8tzong gida purin vi pyrimidin B.Dang D vi . Dang dng phn cis trans Dang dng pin lst — lactam E, Deng déng phin anome cor 2 33. ADN 66 die tin ndo sau day: 56 ‘A. Lun hign dign trong m6 & dang nucleoprotein va thinh phn cdu tgo cia n6 ‘kb bao gid bj phan chia B. La mt chubi polymer dai bao gim céc nucleotid néi v6i nhau bing lién két ‘phosphodiester gita C3 va C5" Ey 35 36 37 38be Khe bit wi ARN wi chubipolymscletid cia ADN oé adi gita C2" va C3" _. Bj thiy phn bi kim nhe (pH= 9 va 100°C) E. Chu tric ghm mgt diy polynucleotide ving va cuba Khe 34. Néu base adenin trong mt phan tir xoin 431 ADN i 17%, vay % cia base guanin ‘tong phn tt ADN ny a AIM B.33% C.4% D. 66% E7M% 35. Chon cl SAI: ADN ‘A. Tée dng 6 mi truimg kiém yéu B.ChiaD~2 deoxyribose (C. Gbm 2 chubi polynucteotd xoin nhau nhi lién két hydro gita base purin vi base pyrimidin D. Chita 6 nhén té bao E. Bj thiy phn béi Deoxyribomuelease 36. Phén tir ADN ghm 2 chubi polynucleotid, 2 chudi nay: ‘A Lin kd wi aban bing ce nhim phosphat B, Buge nb vi ahau bing cu ni dul . Ging nau v hin phin hb ge . Khe nan thin pan ba he .Khiéng thé th i a age 37. Chon ch ding ‘A. ARN va ADN chi cc base pin gidng nan BARN vi ADN chin cfc base pyrimidin ging nhau CAMP véng duge tm tly tong ARN : ARN vi ADN 6 thiy phn & moi tung kiém yu , ARNm chia nh base nite hm 38, Chon edu SAL: A.O sinh vit be cao, ADN & cée m6 kh nhau cia eling mt loi thi gidng nau B, Surhién dign cia methyleytosin la mt de trang & ADN vi khuén CTysbbase: A G T c D.Ty sé: AAT . — #10 18 6lodicd vi oc E, Mot phn tr ADN 6 thé 6 hom 20.000 nucleotid 3739, Clu tric xodn d6i cia ADN bén vimg nhir ‘A Lién kt hydro git cdc base purincenh nha BB. Lién két hydro gita cdc base pyrimidin canh nhaw C. Lign két ky nude gifta cde base purin vA base pyrimidin . Chu trie xodn ea pn tr E Lita két hydro git base purn vA base pyrimidin 40, Chon cfu SAI: Céo ARNE ‘A. Bu 5’ duge phosphoryl hoa B. La céc chi don . Cécéc base duge methyl hoa ‘D. Nbdnh ddi ma giéng nhau & céc ARNt E. Blu 3" ACCA (chitu 5*~3") 41. Chg cfu SAL: ARN 6 té bio 06 ahaa: ‘A. Do ARN bd sung va di song tgo ra B. La chudi don C6 racil= zdenin D. Tich dign Am & pH trang toh ETisé: Ribose Base nite 42. Taymin o6 trong: AARNE B. ARNm bio king nhin C. ARN 6 tf bio 460g vit 6 vi D.ARNE E. Khéng cau ndo trén ding, 48, Thy pn acid ibomuceie bing ribonuclease ty ath age: ‘A. Hin bop nucleoside 2'- v3" phosphat B.Phosphodiesternse C. Nucleosd?-phosphat D, Nucleosid 3°-phosphat . Nucleosd 5*phosphat 4, Chit mio thin pn ef go ota NADP": Ana B.S 235 D.izs E135 38 4s 46, 4,45, ADN Tog B cdc de idm no sau dy 1 Kidag hia wong 2. C6 10 ddi base trong mdi vong xoln 43. Khoing cach gitta mdi di base 1a 0,25 nm 4 Coen plete ole 5. C2 soi déu la nhiing spi ma ha Chon tip hop ating: Al? Bas G23 Das E24 46. ARNm c6 dic diém: 1.ChuBi ARNm gbm ob > 1000 niceotid Lehitm tO oas6ARNE Mo ; 3. Cée mononucleotid trong chudi cé sy sip xép theo qui Inét bd sung d6i base voi ‘ADN wong ng — 4. Lim bg mngthng in tp bg bp prin 5. Che chudi déu 6 thn ciing la CCA (5* = 3°) ‘Chon tdp hop ding: nn Bias C134 bats Babs 47. Vidt tn ede cit saw ow oH Ns oH A 5 8 A B 5948. Vide ten: 49. Vide: goo. Hy He—¢—¢-—8* HH Nie ‘Aderin HOH Tit edw 80 din 87: Din vio 8 wéng: ‘A Chilign quan én a Chi liga quan én b .Lign quan i oda vib ‘D. Khong lién quan dén cé a va b ARN be ADN 50. ..Duong pentose gin véi base purin vit 9 ea base ite 51. Dung pentose gin v6i base pyrimidin 8 vj us 1 em base nit 52, .Chia bose & dang Furanose 5.7m thy 6 ab deol bo bib ‘54, ....KhOng bj thiy phn trong méi trang kiém yéu 55. ..Chta D2-deoxyibose 56. 57. CAN 58, 58. 656... thty phn bi bonucleas uy 57. ..Cbetu tee dang B CAV HOI BIEN CUO! CAU: '58.1Ndu 3 thénh phin hoa hoe eda acid nucleic vA aucleotid: A B c 59, Base pain im ob: A B (60. Base pyrimidin gbm eb: A B. c 61.Li8t ke 4 base nito 6 trong ARN: A B c. D. (62. Lite 4 base nitoo6 trong ADN: A B c. D. 63. Vidt én cia 3 dinucleotid o6 vai td I coenzym: A B c. (64, Cic dang clu tric cia ADN gim cf: A B c D. 6‘CAU HOI BIEN CHO TRONG GIA cAU: (65, Hai va td chinh cia ADN I (A)... va B). 66. Tron ia ARN, de nucleotdnbi vi nau chi yu bing lin kt (A... god ra con mét sé lién két (B). (67, Nuclease la ning enzym thiy phn c&e litn két phosphodiester. Theo v ti hogt hog). ea At be wong ta oye ct in a hub 68, Néu dym vio ca chit @ gyi tn enzym thiy phn liga két phosphotiester tong acid tuck, tl eg chit la ADN, enzym thiy phn duge goi I (A... cm Ki ey chit "ARN ti enzyr thy phn dage go i (3). DIEN BANG HOAC SO DO 6, ea eee ee LA elute “ADN. “ARN Tapa rw Geese B. iH Base pysimiin c. I D. 1 Pentase E K Acid E L CAUHOL DUNG -Sal: Ding gh B), ai gh sai) 70. .....ARN¢ c6 vai trd céu tric, hinh thanh nhimg ribosome. 7h ARN 6 aidu base hi, 72 Blu cba ARNE mang cle nucletid AAC theo chidu 53. 73. ....Cic pentose trong phiin ti ARN la deoxyribose. 74, Trang su logic rie xo 8; dye mith A,B, C,D,E v8 Z, hi ADN loi ‘log gp mda nhl tong ang di ig sis 75, sn Theo nguyen ly bé sung di base, thi A nbi véi T(ho§e U) vi C nbi vd G. 176. ..ADN la mt plypeptd gbm rt hiéu nucleotd, s auceotid thé én da hing wrdu a | n 8 807 77. ---Allopurinal la mypt sin phim twong t pyrimidin, duge ding 48 digu tri ting acid wie mau va bénh git 78. ...cLitn ké co bn trong mt phan tt acd nucleic la ign kétN — lycosid 79, ....Cu tgo cia mgt nucleosid monophosphet gdm c& mbt base nite, mbt dudmg pentose va mt acid phosphoric 80, .~.-Lidn kt glyeosid gita mt base purin vi mt duimg pentose xiy ra gita NI cia base va Cl’ cla 6CHUONG 6 xUC TAC SINH HOC ‘Vitamin 1. Chon céu ding: ‘A. Vitamin A la mgt chdtchdng oxy hd ny min quan tong at. B. Vitamin ote dyn lam ting cali méu, cin tht cho sy héa khodog xuong. Tocopherol 6 vai tr) de higu tong co ché dng mau. . Viti D e6 ban chit hoa hoe thute nm ede hop chit sterol E,Khdng 06 ndo 6 én ding 2. Tp hop mio sau dly gbm toin cf vitamin tan wong nub: A.Bi PPE, Be B.B,, thiamin C,cholealifeol C. By, Retinol, cobalamin, acid pantothenic. D.D,C, riboflavin, Bs E. Khong tip hop nto ding. 3. Tip hop nio sau By gim cée vitamin tan wong nude: ‘A.B,, Be acd patothenc, acid ascorbic. B.BL.BuE,C. CRALCB D.By 6, thiamin, D. E.Khing ip hop mio ing 4. Chqn eu ing ‘A. Vitamin D 1a mae chit cig ony ha ty mi quan tong nt B, Vitamin E 6 ban cht hoa hoc thuge nhém cde hop chit sterol. Visine ung mg cael lt sh ha Kok nung , Tocopherol eval td tong du ha dung méu, E, King 6 noo én ing 5, Tép hop nio sau day gim todn cdc vitamin tan trong nude: AB,D, B,C. B. By, Be acid pantothenic, cholecaleifero. Thiamin, B,C, retinol By, cobalamin, riboflavin, A. E. Khhing tip hop no ding. 6. Tip hap nio sau day gm todn céc vitamin tan trong mo: ‘A.A, EK, acid folic. B.D.E,KB, 6 ih Tes 4z é i 5 5 zZ 1 Tp hap nto seu dy gh ce vitamin tan trong ‘AE, acid pantothenic, K, A. BCA.KD, C.Bi,D,K,E. D. Retinol, D, E, K E. CA tp op ren du i, Tit cd 8 dén cau 12: Ghép céc chit chi cdc coenzym trong thanh phin céu tao e6 cite vitamin tome tng: JNicotinamid A.NAD* 9. sc Riboflavin B.TPP 10.....Vitamin By C.FAD 1H ... Acid pantothenic D.Coenzym A, 12, Vitamin By EE. Pyridoxal phosphat 13. Chon eéu SAL: A. Vitamin Bcd dge oi ya ching bah é phi. B. Vitamin Bs cén duge goi lé yéu t6 chéng bénh pellagra. Vitamin A vai quan wong tong co chicas hin. ', Vitamin E 6 tie dng ivi he tng sinh dy, dda qd nh sinh sn Vitamin i coenym ca dehydrogenase 14, B6i véi vitamin D, chon cdu SAL: A. Tin cit in vtin DA 7-deyochoestr B, Dang hogt ding cia vitamin D; & céc mé chinh ta 1,25-dibydroxy- holecaleifero ee dung ln tng cle mu. c ‘Thidd vitamin Dy s8 gay bénh cdi rong & tré em vib ching mém xwong & putin, D. Vitamin D, ¢6 tién chit 1a cholesterol. E. Vitamin Dy cé nhiéu & dau gan c4, 15. B6i véi vitamin Bi, chon cu SAL ‘A. Vitamin Bae vai tr kichthich sy to mau, BB. Trong céu tric phin tt cia Br2c6 hé théng ving gidng porphyrin vic mét nguyen th coban & git. © C6 mhidu dang ‘hfe nhau cia vitamin By, ‘methyleobalamsin, shu: eyanocobalamin,D. Gée R trong phi ti vitamin Bya 06 thé la gb phenyl, ethyl. . OA jr cie cosa ding pia bin at frm, cyt methyl 16, Chon edu ding; ‘A. Vitamin By tham gia edu igo coenzym TPP. B. Vitamin Bp chinh la acid folic. . C. Thidu vitamin By dua 4a ri logn nghi8e trong trong qué tin chuyén ha «lei, phospho, cho sy héa khong wong. D. Vii Bye miéu trong cé chu, cart, gc chin E, Vitamin C c6 edu tric mach thing. 17. Tap hop no sau dy o6 trong ed dehydrogenase: A. Vitamin B;, vitamin B2, acid pantothenic. B. Vitamin PP, acid ipo, thiamin Vitamin B vitamin PP, sd lipo D. Vitamin B), Ba, Bs Kh tp bop nio ding. Enzym 18, Chon ef ding: ‘A. Enzym duge phan thiinh 6 logi theo thir ty sau: IL Hydolate, 2. Lyase 3. Onydoreducase 4 Ligne Siisomense 6. Transfese B. Enzym xtc tic phan img RR’ + H,0 > ROH + R’H thuge logi hycratase, CC Isczym lt hing phn tr enzym ke nau xe tent phn ig Ke nha, D. Lact dehydrogenase (LDA) c@ 5 isoxyin lt LDH, LDH, LDIs, LDH, vi LDH Catalase 63 isozym. 19. Phin img AH2 ha, duuge xtc tic boi: ‘A Tranfease B.Onydoteducase Catalase D.Lyase E Hidrtase 20. Phin img AB > A+B duge nie tie bai A Lysse B.LDH Isomerase D, Syathetase E, Transferaseaf 21. Phan img RCOOH > RH+ CO» duge xtc tie bi: ‘A. Hydrolase B. Transferase C. Decarboxylase D. Isomerase E. Synthetase 22, nym it chit xc he sinh ie, vn lam tng ng Iuonghoat hte eis phn Chon cu ding ‘A. Hai vé du ing, nhung vé hai khong phil nguyén nbn a vé md. BLVE ding, vE2 sai CVE sa, v6.2 ding D.Cahai védéusai Hii i bu ding, va vé2 1 nguyén na ca vé 1 23, Enzym la chit xe te sinh hoc, yin lim ting sin phim phan img & trang thdi cin ‘bing ota pin ing: (Chon ed cing ‘A. Ca ai vé ddu ding va vé2 gid hich cho v6 1. B. Ca hai vé du ding va vi 2 khong gid hich cho vé 1 C.VEI ding, 2 sai, D.VE2 ding, vé 1 sai E, Catal vé du si, 24, Chon ey ding: ‘A. Ning Itong hogt ha css phn ing enzym lém hom nig lugng hogt héa ete phim tng khdng c6 enzym. BB. Nang lugng hogthéa cia phi img enzym nhé hon ning lugng host hoa cia phan ting khvng c6 enzym, C. Nang Iwgng hogt héa cia 2 phan img o6 eizym vA khong 6 enzym bing nau, D. Enz ng ing tng hot i i phn ng hao E, Tited ede edu tren 25. Phin img cHO CHLOH (OH OH HOP Auge nie the bai A. Transferase B Lyase C. Synthetase oaD, Onydoreductase E. Isomerase 26, Phin img: NH:CONH, + #0. Z—* CO+NHy urge xi the bai ‘A Transferase B. Oxydoreductase C Lyase D. Hydrolase E Isomerase 77. Hai phi ing: duge xe the Bai: ATP ADP 2H Glucose SA ZZ, Glucose-6-P va. Al) —PA ‘A. Kinase vi catalase B. Isomerase vi dehydrogenase CC Lyase vi isomerase D. Kinase vi debydrogenase EE. Khéng tip hop nao trén ding 28. Chon edu ding: ‘A. Da sb ci enzym hogt dong & pH 1-3. BB. Hoat th enzym dat ti da 6 pH thich hgp nhit (pH. (C.Hogt tin enzym ting nbanh & pH 1D. pil ca phosphatase kiém la 55,6 EE. pls cia pepsin a 8,1 29. Chon edu ding: 6 ‘A, Phuong tinh Michaelis-Menten duge biéu thi = Ven ES Me Ku +[S] B. Hing sb Michaels Kili ndng 6 ca oo cb te db phan img det t6i da Wat) , C, Khi néng d§ co chdt bing Kathi the dd phn img dat ti da (Ven) 1D. Khi ndng d6 cia $ tp hom Ky rét nhieu th tbe phan tg et 1@aghich voi ning 65S. EB Phuong tinh Michaelis-Menten duge bigu th ui dang ob th 1 mot dng thing, 3 31 2 3 4mg 30. Cho db th A, true tung bu din A pl B. Ning d9 co chit, C. Neghich dio t6e 49 phin ting An. D. Toe 9 phn img v. EB, Tat cd cfc edu trén du sai 13). Ss 31. Chon cd ding: ‘A. pi thich hgp nbét (pH, cia pepsin = 7. B. pH cia typsin=2,0 C. pH, cia amylase nude bot = 7,0. D. pHlocia lipase nhd hom pH, cia phosphatase acid. E. pHcia chymotrypsin = 6. 32. Chon edu ding: 33. a) Trang tim hogt dng (TTHD) eda enzym tham gia tye ti hyd, vale nhém ha he. ‘b) TTHD nim 6 phan coenzym, ¢) THD do cae ion kim logi quyét dinh. 4) TTHD quyét dinh tinh dic higu cia enzym d6i véi co chit, co ché vin chuyén e, Chon ed ding ‘A.abe ding, B.avac ding. Cc vid ding. D.dding E. Tita 4 eu ddu ding, 34.8) Cl cht ch bp thé (DLT) la mhtng cht cd can ran, 4) Trung tim DLT (TTDLT 6 cich THD m6tkhodng wht dink ©) Chit te ché DLT phn hy ph i enzyn 4) Trong co ché ite ché nguge enzym du tién cba chudi phin img 8 enzym DLT. xy Chom cf dingA.abe déu ding B.avic ding. Coevad ding D.b vad ding Ch edu tn déu as 35. Coenayen A chite: ‘A Riboflavin vitamin B2) B, Acid pantothenic (vitamin BS). . Pyidoxal (vitamin BO). D. Thiamin (vitamin B1), E, Nicotinamid (vitamin PP). 36, Chon ofa ding: ‘A. Coenaym A o6 cite ning vn chuyén acid pyruvic. B. Coenzym A ligt dnuleoti, trong thin phn ed tgo 6 vitamin Bs. C. Coenzym A chuyéa van gbc acyl va gbe ace 1. Nhtm hogt dng cia coenzym A la nhém OH, TE Trong sy tag hop citmt cocazym A chuyéa gbe amin ti acetyl-CoA sang oxaloacetat 37. Coenzym no sau dy khdng chia vitamin: A.NAD BFAD C.Coa. .Pyidxalphospbat Acid ipoie 38. Chon clu ding ‘A. Coenzym NAD gin cht ch vio phn apoenzym ca dehydrogenase cia no B. Flavoprotein chita FAD gin ling léo véi phan apoprotein C LDH chin coenzy li HSCoA.. D. Glucose-6-phosphat dehydrogenase co coenzym la NADP* E, Apoenzym déng vai tro tryc tiép chuyén vén H, dign tir vi nhém héa hc trong ‘phan tng enzym. 39, Chon clu ding: ‘A. Pepsinogen, trypsinogen, chymotrypsin Adu la dang enzym khng host dg, BB Pepsinogen duoc hoa his nh enterokinase CC. Peprinogen do ruyén ty titra D. Trypsinogen bj cit | hexapeptid bién tinh trypsin . Cathepsin la mt enzym ca dich rut. 40. Chon edu ding: ‘A. Glycogen phophorylase la enzym phan ly glycogen. B. Dang hogt héa cia glycogen pho horylase la dang a (king két hop véi phosphat) 1 i 2 a “4© Clyogen yan D gn i gb hosp ng how hg, D. Caltech lip 8 cah rack egenée E,Trong coché ie ché ngupe enzym cia phin img cubi cig ld enzym dip thé 41. Chon ci ding: me 2H ‘A. Khi LDH nce tie phn img lactat_ > pyruvat thi 2H dupe gin vio rihose cia NAD cia LDH B. Ncotnail amid ia pyridoxal phospat. - CC. Isoaloxazin trong FAD chink la noi nhén va nha hydro kh flavoprotein xii the hain tng chuyén hydro. . D. Glucose-6-phosphat dehydrogenase cé coenzym la NMN. Oxygensse I ezym vn chiytn dfn 42. Chon clu ding: A. Hydroxylase ding vai trd trong ting hop cdc hormon peptid. BB, Muitienzym la tap bop nhing enzym xéc tc nhiing phan mg oxy ha Khit. C. Sy ting hop acid béo duye xi tic boi mot phic gp enzym ld acid béo synthetase . Cc cytocrom hoa tan trong bio dich . Oxydase mic tie phin img H02 > Hs0+ % 0; 43. Chon clu ding: ‘A. Catalase c6 nhitu trong dich tigu hoa. B. Peroxydase Id mét Logi dehydrogenase CC. Transainase (aminotransferase) e6 coenzym la pyridoxal phophat. . Trong co ché va chuyén amin ci transaminase nhém amin duge gin vio gic phosphat cia pyridoxal phosphat. i EE. Glucosidase la enzym xi tic sy tao thank lin kétglucosid| 44, Chon eau ding: ‘A. ADN ligase tham gia tng hop chudi ARN. Bi. Alain transferase nic tic phn mg D-Alanis¢-—— L-Alanin C: Decarboxylase xi tic stich him -COOH. D. Dehydratase xc tc ay gn CO, vio pn tht co . Synthase xi te phin ing ting hop via tham gia tc tip ciaATP. Ca hi ing sai (BIS) te cu 45 > 493 45. Coenzym la phn ti hou co, chju nhigt, thug o6 cc vitamin tan trong nude tham ‘gia chu tao, "46, Nhidu enzym Khe nhau 66 cée coenzym Khe nhav, nung c6 thé cing mat lst spoenzym. 147. Cac isoenzym nic téc cing mt phn img nhung ¢6 ofa trie bin don vj khée nhau va amt sb tinh obit ly ha kh nha, 48. Enzym dj lip thé o6 trung tim di lap thé, 1A noi tiép nbn co chat (va cng t5 néu c6), gus bd thay Abi hogt inh ia eazy, 49, Hing sb Michaelis Kw thé hign di Ive cia enzym véi co chit. Ke cing lin, di lye eba cenzym chag cao. (Cu 50 -» 54 Ghlp cde chi chi ede cng ti hich hp vo v0 chdt omg in: 50. ne» Nicotinarnié 51. ores Pytidonal 52, snreu Riboflavin 83. serou Acid lipoie oa ov oT meecal Beceem et Tir cdu 55 59: Ghép chirchi enzym mic téc cho ede phin ing twang ing ‘A. Isomerase B. Transferase C. Detydrogenase D. Peroxydase E. Catalase 55. non bactat +NAD' > pyruat + NADIA 37. 8 39. Te 60, 61 8. 65, Te 66, 6.56, soon Le Alani > D-alanin Glucose + ATP > glucose-6-phosphat + ADP svveuAlenin + a-cetoglutarat-> pyruvat 4-acid glutamic ‘AH, +H20;-> 2H,0 +A Tit cu 60 dn 65, ghép chit ch coeneym ctia eneym taomg tng. 61. Oo Basan 4, 65 Tie 66, 67 6. A.NADP* B. Pyridoxal phosphat C.NAD* D.FAD E. Khong 6 chit ndo 6 tren ~ Glutamat pyruvat transaminase (GPT) Lactat dehydrogenase Glucose-6- phosphat dehydrogenase Sucinat dehydrogenase +» Chymotrypsin Cytocrom oxidase tu 66 dn cau 70: méi cdu gdm 2 ménh a8 (1) v8 (2) ndi véi hau bing chibi vi, >xde dink méi itm ht nhn qué. Tr 10 cia cde edu trén nb sa ‘A. Néu hai ménh d8 ding vi eb méi iénhé nhin qua 'B. Néu bai ménh dé déu diing va khéng cé mi lién hé nhin qu C.Néu (1) ding, 2) sai D. Néu(1) sai, 2) ding E. Néw ca (1) va (2) du sai Enzym thuge logi protein thuln muén xic tic dupe phi c® di 2 thinh phn la spoenzym vi coenzym béi vi apoenzym quyét dinh tinh dBc higu cia enzym va coenzym thé hind lye eda enzym 4b vi co ct. ‘Chit te ché canh tranh tic dung lim ting hing sb Km eta enzym divi ching lam bin tinh enzym. Enzym la mét chit xic tic sinh hoe bei vi né lam gdm nding lugng host héa cis ce phan ig héa sinh mi nd xe tk. n(69, Mot chit xic tac sinh hge o6 tée dung lam ting vén téc cia phén ing béi vi van tbe ‘ola phin ig ting theo nit do (i aigt db 0°C da T? optim. 70. Ca ché te ché nguge Ik mt dang die hin ci ie hd hp thd Biv m6 ing vai rd uma tg ong dda bbe chuyba hia Te cu 71 bn cu 74, 0 bing cc = Chon (A) néu (a) Kom hon b) = Chon (B) néu (b) kom hom (a) = Chom (C) ndu (a) va (b) bing nau 7). a. pH thich hop cho hogt dong ei pepsin » pH thich hop cho hoat dng ei trypsin 7a Tah de hidu i ci pho apoenzym Tih de hu cia ci pha coenzymn 73. a. Hogt tinh cia mot enzym o6 Km=10° moVA 'b, Hogt tinh cia mt enzym e6 Km=10moV 74. a, Nang lugng host héa cho phn img xic tic khOng o6 enzym. ', Ning lueng hoat héa cho phan ing trén 6 hign dign cia enzymn. Tic cu 75 dén edu 98 chon mt céu tré lai ding nh 75, Chon edu ding ‘A Hing 6 cén bing phin ig phy thuge vio nBng dp cde chit tham gia pin ‘ng. B, Néi chung ch pin ig thot hoa db bi phi eung cp thém ning Lnyng mdi xiy rade. . Cae phi ing tg hop cung edpnAng lug cho hogt dng cia bio, cia co ‘be . Qué trnh ne te lim tng hung sin phim dupe go thinh 6 trang tl cin ‘bang. 5, Ch ch én db sai 76. Eazy wie tie phn img sau: R.R'+H-0-H———* R-OH+R'-H thuge log ‘A. Hydrolase * B, Oxydoreductase C Isomerase DiTransferase E.Lyase ” ” m8, ~ 80, BLthe ‘7. Phin tng sau: r = th chy uw. bon amor, Lo +00; snap | | coon coon ‘Thade lai ‘A. Khir carboxyl B. Khir carboxyl oxy hia Khir hydro D. Oxy héa E.Khir 78. Phan img sau diy dupe xi tc bi enzym: 2H:0; 2H,0 + Op A. Peroxydase B Catalase C. Dehydrogenase D. Oxydase E. KhOng cfu tr Ibi no ding. 79, Phan img sau déy duge xe tic Aih+B [A+B A. Transferase B Dehydrogenase Catalase D.Lyase E-Hydratase 80, Phin img sau: 10) +AH: > 2H,0+4 duge ie tie bi: ‘A. Oxidoreductase B Lyase CTransferase D. Catalase E. Peroxydase 31. Phan img sau: Phosphoglyceraldehyd | ————» Phosphodionyaceton ge nie the bai —_— %A Tanferse © Biya C Isomerse Kinase i E, Oxydoreductase 5 82, Hing sb Michaelis, Kin |A. Lit bing sb vind KhOng dBi khi enzym te dung ln cc co chit Khe nba. t 3. Bigwig di xc ma 5 vn te pin ng Hing vin ph ing th da C. C6 1 gid tri dje trumg cho 1 hé enzym ~ co chat nhét djnh va Ikhéng phy thupe | ‘vio ng 9 enzym- t _D. Lé mbt da Tug ph thufe ndng dou ci. E.Khing cfu no ding. | 83. Chu nto sau diy ding (pH.-pH thich hop nha): ‘A. pH cit pepsin bing 8. | BB. pHlcia pepsi lim hom pli cb trypsin. C. pH cia trypsin bing 1,5. D. pHcia trypsin lim hon pH, eta pepsin. E. pHscia lipase tuy bing 2. 84, Chunio sau dy ing: ‘A. Hog 49 ci arginase bi vei D-aginin ln hon Abi voi Largan 'B Hogt ci arginase 4 vi L-arginin li hon di voi D-arginin C. Hogi d9 eta arginase i vi D- va L-aginin bing nha % 1D. Host 4 enzym king phy the vio co cht E. hing edu no 6 tén ding 85, Cau nko sau diy ding ‘A. Kal ning 69 enzym ng vi va the phn ing bing vin tbe th de Kyte th v6 te 69 phn ting, C. Kut I nghich v6i the 4 phan imag 1. Kui phi thude ning 0 co chit li ban iu E Chdeiudéusat a s6.Bidtring: S+E GIS LW PE 9 ‘A. Kuwndng 46 co chit img voi vén the phan img ti da. hth B ky ath, i, . Kus hich vi vn te to thinh phe hgp ES. E.Ci ci du Cys 6 |87. Chon céu ding: ‘A. MG enzym 6 m@t eo chit nhit dink, ©6 thé wie the nhidu phin img Khic hau. . Métcoenzym eé mgt eo chit nhl din, thé tham gia wc te shi phn dg Ke cha C. Mét coenzym o6 thé tham gia xic tic nhiéu phn img khde neu voi nhidu cor ‘chit Khe nha. . Cie izozym cia 1 enzym 6 céc coenzym khéc nhau, Cid edu trén du si 88. Tép hop cée chit nio sau diy tham gia thinh phn cfu tg ca NAD. Cid thp hop tin déu sai 89, Tap hop cic enzym nio sau diy khéng cin cé coenzym: ‘A. Peptidase trypsin, amino transferase. B. Chymotrypsin, pepsin, araylas, CC. Maltase, chymotrypsin, iyase D. Lactat dehydrogenase, decarboxylase, deaminase. E. Khong tip hop nio, 90, Hai phan tng sau lin lugt duge aie te ba Lactat Pyruvat NADY NADAL UDP Glucose + (G)y ———» UDP + (Gat ‘A. Dehydrogenase vi synthetase, B.LDH va transglucosylase. C. Oxidoreductase va isomerase. . Pyruvat carboxylase va glycogen synthetase E.CAA vaB dtu ding 91. Chan céu ding: ‘A. MBi enzym o6 thé 6 nhiéu apoenzym khéc nhau, mi ‘coenzym tuomg img cho I ery dc iain B. Coenzym i pn og tS cb bin chit fon kim logit fp thm gia vin chun ifn ti, Hyogen, cf nhém ha hg trong pn ng do enayn we te . Tinh de hia ca cht in enzyme qué bi phn poenzym. Enaym xtc tic im ting van tbe phin tng la do lam tng ning lugng hogt hoa EACm Dae tig 92, Clu tee vg sa dy hig non tt ok ht we tn, TRU: as aw bs — crac = Nom ‘A. Adrenocorticotropin, B.Aldosteron C. Testosteron D. Acid mat E. Vitamin D 93, Chon edu ding: A.NAD li coenzym van chuyén hydro, trong céu tao o6 vitamin By, 'B. FMN ld coenzym vén chuyén din ti, cu tgo 06 vitamin Bo, CC. NAD vA NADP du cf vat nhur nhau la vn chuyén 2H cho qu trinh thoi hoa cfc chat. . D. mI enzymn van chuyén din ti, c6 eoenzym la nicotinamid. Tedd se 94, Chgn cfu ding nh ‘A. Kinase v transaminase i enzym ogi 2 2B, Enaym xi the phn img GaP —> G 4H,PO, thude loi 3 . Trt loi enzym ty pin, da sé enzym hot dng du ln 6 coenzym, D, Caalse vi peroxydase la enzym logit E Tited du ding. 95, Chon edu ding: ‘A. Transaminase c6 coenzym la vitamin B. B. Kinase va phosphorylase déu la enzym chuyén nhém phosphat, chuyén ‘phogphat tir 1 cht hu co phosphat sang eo chit. C. Mattase, amylase, peptidase thue lai glucosidase. 1D. Cytocrom la | hemoproten & mang trong thé ty, vin chuyén 2H. E, Khong céu nto 6 trén I ding 1%rai yén | 96. Xem cle ding bidu din 1,2 3,4: ‘A. Dung I: phuomg tinh Michaelis Menten, biéu din v theo [S}. B. Dring 2: phuong tinh Michaelis Menten, biéu diéa theo eal) ©. ung 3: tng hp cht cb cnh wan, D. Dab ung pc cht ed ogo anh, E. Tit cd déu ding. 97. Coenzym A chit vitamin: ‘A. Riboflavin (vitamin B,) B. Acid patothenic (vitamin Bs) CC. Pyridoxal (vitamin Ba) D. Thiamin (vitamin By) - E. Vitamin PP (vitamin B3) 98. Méi quan hé gids bign thin ning hugng ty do chun va he s6 cn bing phén ing | dug bi didn theo hte A.AG.=-RT logk B.AG, = RT lopk C.AG)=RT ink D.AG.=- RT Ink E,8G,=- R/T logK. Tir ctu 98 én eds 107, tr li bing cick chon tap hap ding nha. A.1,2,3 ding B13 ding C.2,4¢ing D.2,3,4 ing +E Thted déu ding99, Doi véi ca coenzym: 1 FAD cha vitamin li thiamin (B,) 2. Coenzym A chia vitamin it aeid pantothenic (B3) 3, NM” chia vitamin PP (B3) 4, Transaminase chia vitamin la pyridoxal-P (B,) 5. NAD" chia vitamin f4nicotinami (B) 100. Bi voi cdc cht we ché canh tranh (let) ete dg lam tg Kuyt ug tn Vou spin ing 2. lett hte hn eg ib oct, ng vo ot TTHD ei nay, 3. Khi thay 48i ndng dé ca Ict vi cia co chit, c6 thé anh hudmg trén mite 46 ite ché. 4 Malo tc Te ee acta 5:Ttisedng lam Vo apn in, kg dah hg tn Ku 101. Enzym di lp thé: 1. Tg li tng enzyn cia khés, quan tong rong céc con dg chuyén 2. Cé nhigu TTHD 4 hin cic effector la nhiing chit hoat héa hoge tr ché DLT. 3. Sy ie ché ngupe (Feed bac inhibition) thubng do sin phizn cubi ela cud teak chuyén hoe, dng vi tb chit te ché DLT, we dg ln | enzym DLT tamg cng fa on dg chuyéa hoa és 4, Lang enzym thus logienzym protein thud, 5 La nhing enzym o6 clu tri dc big not TTHD dé tiép adn thém cde cht host, ha hy Ge ehé DLT. 102, 1 ei a to thio pte bop El (enzym-chlt de ck dua hich 8 ob wp te ob can wan, : 2. Khisirtao tinh hc bgp E- thu ahi oy cca anh 3. Cult te ef gn tanh King lim thay i gl K 4, Chit te ché can tranh lam tng git tri Kn 103 1. Chit ae ché can tanh khng lam thay Bi gif tr Vn: a ph tng. 2. Cite ché cant tran im tng gi tr] Kus 5, Chitite ch khdng ca tanh am gi git 8 Vaux 4 Chit te ch khdgcaah tranb kg lim tay 48g ti Ky 5, Chit eb can wan c6 cfu to hoa hoe gin gibug eu cht. 104, 1. Céc eh te ch dj gp thé dupe coi nu 1a nbimg chét ie ch can frank. 2, Trung tim dj lip thé 6 cdch xa trung tim hogt dng 1 khodng eéch nha dich. 3. Chit ite ché dlp thé xi tée sy bien tinh cia chudi polypeptid enzym, 4 Thek ee ey lp duc elu we bin don 0 « 10 Te 10. 1cae 105. |. TTHD (tung tim hog ng) cis enzym thar gate peo cd vn cuyda ign ‘ht, hydro, cdc ‘nhém héa boc cila phan ing, 2. TTHB quyé inh tinh dc hig dl v6i co chit ea enzym, 3. Sur kt hop dc hibuenzym ~ co chit do e6 syn khop vi clu tie gta TTHD va cochit 4, TTHD lat du trv 3 chidu, tg nén thuong do nhiing aminoacid & xa nhau, ‘5. TTD do cc ion kim loa qu dint 106. 1NAD" lt coenzym vin cuyén yo, wong thin ln eu goo vitamin PP 2. Cl isozyme I erzym xe We cing I phn ing vic edu tc hin don wi hie ha 3. LDH gbm 5 iooym - ‘4. Cé sy an khép gita trung tam hoat dng cia enzym va co chit. 5. Proenzy la dang enzym kg hoat dng 107. 1. Dehydratase 2 Decarboxylase 3. Aldolase 4. Glycogen phosphorylase 5, Glucose-6-phosphatase 108, 1. Sulfamides lt che ché cqnh tanh eis PAB (acid para-aminobenzoic)nén otic dung diét khudn, 2. Swe ch canh tanh tnh chit khong thudnnghich, 3. Héa rj liguchéng t bao ung thu dng cd chit chéng chuyén ha tung ob chu tne tuong ty ed base purn hay pyrimidin. 4 Buig bidu dfn v theo dBi voi enzym dj lip thé It ding cong hyperbl theo phon tinh Michaels Menten, 5. Ton chor (CT) li chit hot ha cba cle protease Tir edu 109 > cd 112, chon edu SA 109. Trong thinh phn chu tgo cia coenzyin A e6: A. Acid adenylic, B. Acid pantothenic, C. Thioethanolamin D. Acid Acetic, B. HN CH ~ CH ~ SH, 110. Pn img sau dupe nie ie bi G6P > GlucoseA. Phosphoestease BB. Transphosphorylase C, Hydrolase D. Ghucose-6-phosphatase E. Enzym phan logi 3. 111. Cée enaym dehydrogenase o6 cle coenzym sau: A.NAD" B.NADP* FAD D.Coa, E.FMN 112, Cytocrom A, La enzym vgn chuyén dign tit B.Laenzym ca chubi bo bp tf bio, & ming trong thé ty. C. Van ebuyén ting ofp sign vi nbd cucazym tuong tx HEM, phn trang im jon sieve tgp chuyén din tir 2Cytb Fe” = 2eytbFe™ D. Gbm eb nbitu ogi cyt a,b. E,Cytoorom oxidase cing enzym ho hp Warburg. Hormon 113. Xée dah sy ding (D) hay sai (S) cia nbiing edu sau: A. Tébo thing bdo titra chit bdo higu hay tt chong tin, B. TB tiép nhén chit bio higu duge got la ré bio nba, C. Sy ket hep cia chat thong tin v6i thy thé ld King cé tinh chit fe hig D. Yéaté ting tring thin kinh, histamin, prostaglandin déu la nhing chit bo fn tic. 1d hoa hung dng té bio di toan li chét bio higu ty tc. 114, Xée dia sy hing (D) hay sai (S) eda nbitng cu sau: A. Acetylcholin,taurin, 4-aminobutyrat déu la nhitg chit dn truyn thin kin 'B, Pheromon la cht béo higu ty tie CC; Hormon thube hf théng vido tic ni hay thong béo ngi tit . Prostaglandin vita la chét tung gian ha hg, va la hormon, E, Elisa king duge sit dyng 42 xde inh nbitng phn tir én, 118. Chon ed ding: 2 ‘A. Hormon duye ting hyp 0 té bao np dt vk qua dng la vio mu BB, Hommon chi due ttre boi nig *yén ni tito edu tric vi rank gi rd ring. n ue 1%6 C. Mbt tuydn ngi tidtc6 thé titra nhidu hormon Khe nau va mét loa ¢é bio dich €6 thé tiép nin nhimg hormon khée nau nhisnhting tho thé de higu ic nha. D. Tit ed céc hormon Adu la protein ~ EB Tit cA ede hormon édu dupe vin chuyén trong méu dui dang két hop vi protein. 116. Tap hop nio sau diy gém céc hormon du thug loa steroid: ‘A. Adrenalin, Ts, progesteron B.Nor- adrenalin, glucocorticoid, estradiol, C. Catecholamin, minerlcoricai, aldosteron. D, Glucagon, Ts, testosteron E. Estrogen, cortcoid, androgen 117. Chon eéu SAL: A. Thyroxin, Ts, akenalin ul hormon amin, 3 Tin son ig home ep . Mormon gin vi thy thé dc ewe bo. D. Thu thé cin aenalin nim &nhint bio E.Cée androgen dda e619 carbon 118. Xée din sy hing (D) hay sai (8) cha nhtng ed sau: ‘A.Th, Te catecholamin dl ln xu ei tyroxin B.T, Ts du c6 phn chung i thyronin do 2 pn i yroxin tao thin C. Cie nguyen tid cia tyroxin gin 6 cde vt 1,23, 4 D.Ty, Ts cng due coi la cle acd amin, E Adtenaln vi nor-adrenalin 4 enh catechol vi hm ain F. Trong cng thie cia nor-adrenalin ¢6 nhém metyl (-CH,) gin yéi nhim amin (thay cho bydro). 119. Chon eéu ding: ‘A Catecholamin hormon va lipid. 2B. Tel nhtng boron wa ne C. Eicosannoi i dia wut cia cholesterol 1. Hormon pet bao gm cé hormon cé bin cit pep (ui 20 acid asin), polypeptid (20 acid amin, PTL ui 7.000), protein (PTL én 7.000) nhieu aid amin), glycoprotein, Kh vin chuyén trong mau cc hormon protein dé duve gin di poten, 120. Chon edu SA: A. Hormon thye hién ¢6 tae dung trén md dich khong phai la tuyén ngi tide, B, Hormon giai phéng la hormon cia ving dui dBi 6 téc dung kich thich tuyén yn ct homon tuo ing c. ich tl hormon ea tuyén yén trade o6 tc dung kich tuyén ni tid trong ‘ing ché tet hormon tuomg ing, 81D, Ving dudi di khong ché tiét hormon thye hign. , Tuydn yéa tude ehé tit hormon thye bign li hormon ting ting hay sommaioopin. 121, Chan ed SAI: ‘A. Vasopressin vi oxytocin li. nhing hommon peptic ving dudi di 1 B. Vasopressin la hormon ching Ii tiéu, ¢6 te dng d6i vr sy ti hp thu nade 6 6ng thio. t . Oxytocin c6 tée dung larn co co tim D. Aldosteron co te dng ddi vei sy ti hip thu Na” 6 Sng thén, E. Aldosteron 6 21 C va thuge logi mineralocorticoid. 122, Chon cau ding: ‘ATs va Tuoi yen gp 0 the dung tng cag chuyén hia co bn. B. Calcitonin la hormon cita tuyén tuy. . Tayrowopin releasing factor (TRF) la hormon cua tuyényén, TRF kich hich tyén gdp tte glucagon. E, Calcitonin ¢6 tie dung gay ting calci buyét. 123. Chon edu SA: ‘A. Prostaglandin la hormon thu log din xu ea acid béo 20C B. Cle ctecholamin éu 6 nn catechol . Cle phenol steroid e6 19C D. Exeadiolcdn duge gp a dihydrofliculin .Eatogen 6 ie dng lim dy nid mpc tr cung. 124, Chon ctu ding: ‘A.TSH o6 trong lugng phan uk (ILPT) 1.500 B. ACTH hay corticotropin gim 49 acid amin (C.FSH li mot polypeptid gdm 29 acid amin 1 oy . Somatouropin hay GH gom 51 acid amin E, Prolactin la protein (TLPT ~ 23,000) e6 tc dung ich thich tuyén sta tiér sta. 125. cho tu SAL ‘A. TRH li mét peptid gim 3 acid amin o6 tic dung kich thich tuyén yéa tiét TSH. 'B. PIH la hontnon cia tuyén yén cb ban chat la glycoprotein, ‘C. SRH la peptid gdm 44 acid amin c6 tae dung kich thich tuyén yén tiét STH } DLCRI gi #1 an ic the dng Kc hh yen yen ude ult ACTH | E-MSHI6 homo ea yén te, 126. Chgn céu SAL: ‘A. M@t hormon c6 thé ¢6 nhieu co quan dich, B. Cie Leh doy -yén tit ra 06 tde dung kich thich mot s6 tuyén ni tiét ché viét hormon. C. Hormon hogt dng véi néng 4 khong mgt mol/L (M) BD. Adrenalin ¢6 tie dung nhanh (sau thoi gian tinh ‘bang gidy duge tiét vio miu A ay ting dng hays) ; Estrogen ing ote dong chim, sau ki due i vo mau thi gin th ‘bling gid hoe ngay). 127. Chon céu SAL: ‘A. Thy thé cia tyconin vi steroid in 6 be rong bio, j 3. Hormon gdp tang gm; va te tiodthyrnin vi teraiodehyrnio f C. Thyronin do 2 phan tr alanin két hop voi nhau. D. Nor-epinephrin la epinephrin mit nhém methyl (-CHs) Glucocorticoid e the dng i wi chuyén he lucid 128. Chon eluding: ‘A. Cée corto tang boron an ong nie B. Androgen cé tic dymg lim xuit hién vi bdo t8n dc tinh sink duc nam, ting tng ho prot ° . Progesteron i ormon sin de nto 18C D.Nbin gonan gim 15 carbon E. DOC (deoxycorticosteron) thud logi glucocorticoid. hhay 129. Chon fu SAL ‘A. hai ogi thy thé: thy thé nim & mang té bio (TB) va thy thé nim trong TB (io tuomg va nhs, . BB. Phite hop hormon ~ thy thé trén ming TB kich thich go chit thing tin tht hei (thi dy AMPy) . C Phite hop hormon ~ thy thé ni bao la chit thing host dg cia ge, tt 46 anh hung 16 sy sinh 1. 1,25 (OH)2-D3 cf thy thé nim trén mang TB. E, Steroid va thyroxin e6 thy thé ndi bao, thi hai, 6 the ding len se ng hop protein 130. Chon eu ding wa, ‘A. Thu thé tén ming biol hog polysacrid nim 6a mang fbi, B. Hormon steroid gin voi thy thé theo kigu “chia Khoa - 6 Khe, thy thé git ‘nguyén cau dang nguyén thity. TSH . Advenalin glcagon, ACTH, TSH IA nhOng hormon tng véi et thing tin thirhai a AMPv. ' . MSH, PTH ing véi chit thong tn thi? la GMD. , Insulin, GH img wi chit thing tin thi hai Phosphatdyinasito. 131. Chon céu SAL: ‘A. Thbi gian dy t 6 tuyén obi tét la vai git (steroid), hidu tuln (thyroxin, 1 ted ~~ ngty (hormon peti) hide ngiy(ctecholamin. B, Steroid va thyroxin cin ob protein ti 6 huyét tuomg, la clei hosel 85C. Boi sng cia hormon trong huyét tuong duge tinh theo git (steroid), ngiy (Ghyroxin),phit(hommon ppt), gid (ctecholamin), ‘Th gian tic dyng cia hormon Sau Khi vio méu duge tinh theo gi, ngiy (steroid), iu ngly (hyroxin), phit bode gi Ghormon peptdl, ety (catecholamin) , Homion pptid due bi tra Kbit bdo ni it theo co eh Khuéch tan qua ‘ming bio trong. 132. Chon edu SAL: ‘A. Cortisol, aldosteron, estradiol, catecholamin & dang host ng ngay sau Ki Auge tbg lp tong t bo nit. B.Té bio a cia uy tbag hap proglucagon (37 aa, tr 46 tgo thin glucagon (29 a) C. TE bio 8 cia tuy thng hap preproinsulin (104 aa), 6 tg than proinsulin (aa) va insulin (1 a). . . O eée mi sink duc thir cfp,testostron bién thinh dinydeotestosteon host dng yéu hon E, Vitamin D3 (chlecaleifero)bién thin |,25-tihydroxy-cholecalefeol v6i sit tham gia cia da, gan vi thin 133, Chon elu ding 'A.Tuyén gid tang ld md dich de higu a TRH B.Phive bop hormon - thy thé nf bio tc tp tic dung lénnhitu enzym gy dlp ing sinh Ij. C. Adtenlin gin vio thy thé adrenergic tén mang té bio gan va thng qua G- ‘rosin ma hogt hoa adenylyl cyclase xe tc sy tao AME. D, Protein kinase A gh 3 loa bin don vi E Protein kinase A xe ti sv Khit-phosphory! dBi vi phosphorylase. 134, Chgn cfu SAL ‘A. Glucose hyd ca kih hich tuyén ty it insulin. B. Nang 9 thm thu ca huyét tung ting kichthich sy it ADH. C. Corticotopin (bay ACTH) kich hich vo thug thin ché tt cortioid DHE thd thin kind wang wong ih tng dn ton ich ig vi hE thng gi wit E. Ngoai co hé phn hi dm cn ob co ché phn hBi duong (hi du estogen di vei Li, 135. Xe nhs ding (By bay sai (S) 8; vi ee eu su: ‘A. Tair nghifm mia dich phéng xa (RIA) dug thyehign theo nguyén te can ‘ran gitta khing nguyén dénh déu phong xa va khing nguyén khing inh di khi gin ket véi lugmg khéng thé bn ché, 3. Thirnghiém do phn xa - miéndjch (IRMA) duge thy hign da trén nguyén te Kj thd “bah Kep” wi mt lay tia Kh th gn v0 gi he hn ‘i lugng tia Khang thé dh dd phong x8 ee 86 BF 1 Bety ngay sity w ki n(29 host Gise 2G angi nasi EER NEP ened 137, Cée hormon ndo sau dy li nhimg hormon gidi phéng cia ving dui db Tog tt git nin cheap (ELA) ery due dng nh da ‘ .Trong kj tht ti nghitn mda djch ting cudmg bing enzym (EMIT) due si dong inh uog ee pe stuf sero vou E, Bie idm cia thr nghifm mia dich hip thy itn ket enzym (ELISA) li cin ‘tach rgng phic bop King nguyén ~ khang thé danh dia bing enzym kid chit démh dé ty do nhir mt gid rl o6 gin khing thé khiing dnb du. £46. Chon céu SAL: ‘A. Tuyéa tng ché tit melatonin mit sin phim chuyén hia cia trytophan B, Tuyén yén gm tuyén yén trude hay tuyén yén bach, tuyén yén sau hay tuyén yn thin kin vi pha gta hay phn trng ian bey thiy gia CC. Ving dui Bi che it hormon gi png, hormon te ché va céhormon the . Vaopeain (ADH) vt oxytocin dave tg bop & ving dati vk doe chin dln dy uy ns E-Twylnyen cht TRI ‘A. ACTH, TSH, glucagon. B. TRH, SRH, GnRH, CRH. C Prolactin, GH, vasopressin. D. PTH, oxytocin, GHRIH. EE. PIH, SRH, MSH, 138, Xée nh sy ding (B) hay sai (S) d6i vic esa: ‘A. Nhém hormon GH-Prolactin-CS gém nhimg hormon protein chia khong 190- 199 acid ami. 'B, Nhém hormon glycoprotein cia tuyén yén true gdm TSH, FSH, LH. CC. TSH, FSH, LH va CG du 6 2 ban dom va va 8, tong 4B hog in sinh hoe dc hitu 1. O tuyén yén trwde ho hormon peptid tao thénh tt: POMC gbm ACTH, MSH, LPH, enérophin, E, LPH gdm 39 acid amin, . F. Seendorphin gim 18 acid amin va &-MSH gbm 31 acid amin. 139. Chon elu SAL: A Thyroslobuln tif hormon eda Ts, Ts B. 75, Tenim trong phan ti thyroglobulin va duge gai phing nh tc dung thy phn thyroglobulin oa protease va peptidase ©. Ty, Te duge vn chuyén trong mau dudi dang két hop v6i TBG (thyroxine- binding globulin) vi TBPA (thyroxine-binding prealbumin) 1, Hormon gp trang etic dung im ting Ca huyt. E, Tuyéngidp cbn ch tit calctonin-mgt hormon peptd e632 acid amin. 37140, Chon cu ding: 4 eatin ing rte i det ln. Bi. Honmon eén gdp la din xult ea aci amin phenylalnin. C.NBngah Co hides be eo wd PTH D.C v6 thaong thin ving edu tg0 gluseoconiesid, ving bs tao hormon sinh duc ving lui to aldosteon, E, Adrenalin 6 tic dng lim chin nhip tim. 11. Xée dah sy ding (B) hay sai (8) di vei cde edu sau ‘A Consol I glucocorticoid chin 6 te yng trénchuyéu hs glu B, Deoxycoriosteron la mineralcorticuid chsh ci v6 thugng thn C. Aldosteron été dung ting thi Nara nue tu D. CBG li protein vin chuyén corticoid. , Vo thugng thin tort ahiéu estrogen. 142, Chon et $AL: A Progesteron duge yo think & thé ang, v6 thugng thn, B. Estrogen lim dy nos mae t cung. . Androgen chi yu l8 DHEA. ‘D. Sy diéu hda ché tiét hormon sinh dye duege thye hign theo hé théug ving duéi bi ~tuyén yen ~taydn sin due noi wong 466 phn hi &m vcd phin bi dong. E, Androgen li trod 19C va ct dung lim aut hin vi bio tn A tinh sinh iy nam, ting tng hop protein. 143. Xée dinh sy ching (B) hay sai (S) d6i véi cae edu sau: ‘A. Tyongtibu dio Langerhans ca tuyén ty cde té ho a tit glucagon, t bdo tb hlo D td somatostatin Bi. Jaglin la me chudi polypepid gbm 81 sci amin. C. Te bio cén cu thin sin sinh renin ~ mt enzym thiy phan protein. D, Angiotensinogen la m6t a2-globulin do gan sén xuat, 144, Xd din ying (B) hay sal (S) Bi vi ce sau: ‘A. Renin thiy phan angiotenoinogen tich ra mt peptd 10 acid amin, te a angiotensin | B. Enzym chuydn di angiotensin (ACE) thly phn angiotensin 1 to thin angiotensin II 8 acid amin 6 tie dung gly ting huyét &p va kich thich v6 thug thn tng tt aldosteron C. Gastrn la polypeptid gdm 25 acid amin D. VIP c6 28 cid amin v.e6 td dung hich hich ruyén ty it bicrbonst 145. Xécdinh su ding (D) hay sai (S) 46 voi ede cd sau: ‘A. Seeretin co 32 acid amin va kich thich da day tét acid clohydric B. Cholecyotokinin-pancreatozymin e6 33 acid amin vi kich thichh sy co bp ti mit.ae C. ANF 6 28 acid amin vie the dung gy ting bai xudt Na’ ra nude tid, gly he hyd gp. D. oietin 1 mgt glycoprotein ©6 166 acid amin va c6 te dung ting t20 146. Ké tén bai hormon trong mi loai hormon tuong img + Hormon amin 1 2. = Hormon steroid 1. Tie thugmg than 2, Hormon sinh due = Hormon peptid: 1 2 + Hormoa protein: 1 2 Tit edu 147 -» 151: Ghép cd cht chi hormon dhege si xudt ra bd cic tuyén tong ing: ‘A. Glucocoticoid BLACTH ADH D. Catecholamin E. Glucagon Y4T, csssessneenenv eevee Ty thug th Yen tube 149, V6 thugng thin 150 cium sau ISL, cesasentnee vTy Ti edu 152 dén 156: Tra oi bing edch chon mt hay du ci lem quan v6 ee cu tong ing ‘A. Glucagon BPTH C.ADH D. Adrenalin E, Glucocorticoid 152, Lam ting dung huyét153, Lam ing iu non, tng cal mau 154 Ki thiéwgy chimg i thong (finbte insipid) 193, Thue loa oman polypeptid 156, Khi ting qué nhidu gay béoh Cushing 137. Tép hop ndo sau gbm ede hormon steroid: ‘A. Androgen, adrenalin, thyroxin, B, Glucocorticoid, progesteron, nor-adrenain CC. Estradiol, catecholamin, testosteron, . Estrogen, corticoid, androgen. E. Ca 4 cfu du sai, 158, Tép hop no sau dy gbm céc hormon amin: ‘A. Adrenalin, T,progesteron, B. Glucocorticoid, estradiol, nor-adrenain C. Catecholamin,aldosteron, mineralocorticoid D. Thyroxin, Ts, adrenalin. Cid edu dbu sai. 159, Chan ofu dng ‘A. Adrenalin glveagon, thyroxn in xt i acid amin fron B. Tit ed cde hommon sinh dye nt vi nam du tube loi steroid va tte do ede tuyén sin dye itr. . ACTH, TSH, MSH, noradrenain, calcitonin, insulin thge loi hormen pep protein, D. Aldesteron, hydrocontisol, ADH thug ogi hormon steroid E, Khong edu nio 6 én ding, 160. Chon tip hop e&u ding: A.1,2,3 ding B13 ding C24 ding D.2,3,4 ding E, Tit cd dbu ding ‘ 1. ACTH tude logikich t8 (tropic hormon) la mbt peptid do v6 thugng this tét a. 2, Cc hormon amin, peptidtée dung bing cich gin vio thé nn de higu 9 ming 18 ‘bio 3. Hormon hoat ding véi ning d® Khoing vai mol, thdigian téc dung chi nbanh, chm tty log. 4 Tuyéa yén trae tit ra phi Kin ic Ki . 5. Ted hormon thude Toa steroid du do vo thuong thn tie 34 40 5.0ee pid, CHUONG 7 KHAI NIEM CHUYEN HOA CAC CHAT 1.Chon nhing eu ding: ‘A. Chuyén ha ce cht cdn due go la qu rink ao dich 'B. Qua trnh chuyén hia tung gian xi ra trong ee bénh dich tigu a. CC. Qua tinh ng héa gdm 3 bude: tiguhéa, hip thy va ing hap. . Trglyceti bi pn gid & rapt non than glycerol va acid bio, vi duye hip th qua fnh mach cia gan. E, Sin phim titu ha cubi cing cia gluid cde oligonucletd 2. Chon nhting cu SA: A. Su di héa cée di phi tir dn dén nhimg sin phim cudi ciing dio thai ra ngodi. B. Sy thoai héa cdc chit gidi phong ndng long, 90% dudi dang dy tet (ATP) va 10% dudi dang nhiét, . . Ning ugg gi ping tr ning qu tein thodi a mit phn 8 dug t bio sir dng dui dang cé cng ea be, hoa hoe, thm hl, D. Phin img thiy phn dng vai rd quan trong nt trong sy gi png ning lugng tnt sy phn gti lucid lipid, prot. E, Glycogen, trghycerd I nhtng hit ditt ea co thd 3. Chon hing cu ding ‘A. Phin tng lién hop la phan img ghép phan img ting hop va phan img thodi his. B. Phin img thiy phin ATP gti pong 33 Keal/mol . Su thiy phn Ge? (GaP + 10> G + Pv) gi pong 7,3 Keaino. D. Trong phan img lién hop thutmg ning long gidi phéng tir phan img thodi hoa 20 hon nll cla cho st ng hyp Phin mg tng hop Ia phn mg phat ning 4. Chon nbn cfu SAL: ‘A. Chuydn ha trunggian didn ra qua 3 gai dopa: di phn tt + don vi edu go ‘+ Acetyl CoA ++ chu rink Krebs. 8. Ning lung due gi png nhidu nh iat dogn 1 C. Acetyl CoA thodihéa trong chu tinh Krebs thinh CO, va H,0. _. Maltenzym (xe te mat chu pining thubng gm 2 ~ 20 enzym, E. Nin di sing ci protein gan cht la 200 ng 5. Chon nhing céu ding: ‘A. Bing ca mt chit igus gta gg thi —Iuomg np cia chit B. Bi-lang am khi lugng nhép bé hon lugng thai .Ly tim dich ng bo vi 60g tong 10 phit th ch én dupe bosom vémictosom 1‘D,Nalng chit dng vj abt cht c6 cing sb dint, cing 56 neutron va ke ET ay) 9C,%5, Na, Fe, 1 db I ng ct bg vi png Tice 6d edu 11, xd inh eu ing hay si: 6. Tong gut nh ng, i ogni Ro ta i ong ug cn i ho il don ug hyp. 7. Dj hoa la sy phn gi, iu hoa ce tite An. 8, Nhing chit ding vj la nhtmg chit c6 cing s6 proton, ciing sb dign tir va khéc sO. neutron, 9, Ding ha tyo ra nding lugng. 10. Tu héa, hép thu va ting hgp la 3 bude cia qué tinh dj héa. 11, Nang lugog eda qué trinh thodi ba cdc ebit, a ra dui dang abit chi Khodng 50%. 12, Chon edu SAI: ‘A, Chuyén hoa glucid la chuyén héa trung gian rong té bio 'B. Chuyén hds lipid la chuyén hoa trung gian trong té bio . Chuyén héa protd ld chuyn héa trang gian trong t8 bao 1D. Chuyén héa cde chat chi xay ra trong té bdo E, Chuyén héa ce chit bao him tidu hoa thie dn, hép thu céc sin phim tiéu hoa ‘va chuyén héa trung gin 13, Chen ctu ding: ‘A. Chuyén ha tung gan edn dupe goi i qu rah tao Bi chit gta co thé sing vib rung . 8. Cyn hs tung gan gbm ce qu rah hae aay ra trong eo thé C. Chuyénhés prot la cen hs trang gan rong bo D. Chuyén hia ce chit ch yea rong bio E, Chuyén a trang gian bao him iu hs thic Ao, hp thu cic sin aim teu hv chuydn hie cic cht 14, Dida e6 nhing de dim sau: 1. Dj héa fa gué tri thiy phn ede di phn ni c6 tinh de higu ci thie thé cic dan vi chu tao 2. Thodi hoa li mgt kau eta dj da c6 gi png ning huang 5, Nang luong gi phong tr nhing qué tinh thodi he mot phan sé duye bao sit dung dudi dang céc cBng co hc, hoa hoe, thar thu... 4. Phin ng thiy phn dng vai tr quan trong abt trong sy gi phong ning luomg tient su phn git gcd, lipid, protia 25. Nang lugng cia qué trinh thodi héa cde chit, t3a ra duéi deng nhiét chi khoing 50%, Chon Gp hop ding: - A123 3,45 5 moo 15, BBng héa c6 nhting dBc diém sau 1. BBng ha la qué tinh tog hyp cfc i pn i 6 inh A hig eta eo the 2, Tigu ha la mot kh cia bog hd, xy ra Ki 6 mt ca cc enaym thy phn & trong cfc dich iu ha 3, Nang lugng gai phéng ti ahtng qué tinh ddng héa mpt phn s8 duge tf bd sit dung di dang cé cng coho, ha hoe, then thi 4, Phin mg oxy a Kh ing vai quan tog obit trong sy gli png ning luong ti nhig sx pin gi glucd pid, proid 5. Tituhéa talycerid lab aig enzym lipase & rot (Chom tip hep ding: 16. Di ha ls ‘A. Quitrnh ty ning hug tg ha Meth ca tit hin ii ping nag ung, CQud ah pn gi che dtp eb bo md thin in phim do thi '. Qui rink thy pn cc dtp tinh dc heb th han fe dom Wichu tao E, Qué trinh gim 3 bude tiu héa, hdp thu va ting hop 17. Bling ha ‘A. Qué trinh i dung ning hug tr ku iu hd B, M@t khdu cia qué trinh ting hop (C Qua tinh thy phn cde di phn tr 6 tinh fe higu cia thie dn thn céc dom view to D. Qt in bin di cde dai phin tit c6 tinh dic higu cia thie an thanh cde don vi E. Qué trink bién di cdc dai phan tir hw co 6 tinh jc higu cia thite an thanh ‘dai pn i 5 tine higu cia eo th 9318, Chon cu ding: ‘A. Phin img lién hyp 1 phiin ting ghép phan img thiy phan va phin img ting ep. B. Phin ng thy pin ATP gi phong 7,3 Kealino, . Surthiy phén O,P cin 3,3 Keal/mol ©, hin ng tg hp pn ng png ning hong Tht ddu ding 19. Chuyén héa trang gian ‘A. Qué trinh téng hop din ra qua 3 giai dogn: dai phan tit «> dom vi céu tao > ‘Acetyl CoA ech i Krebs. ‘B. Ning lugng duge gidi phéng nhiéu nhét 6 giai doan | C. Acey! CoA thd ha rong eh tinh citi hinh CO v8 Ho. D. Multienzym (cic tic m@t chubi phan img) thuémg gdm 10-20 enzym. Ni bi sng berger 1 200 ng 20. Chg eu ding: 94 ‘ATi a qu inh thy pin de pn ah wansferase BSc hip th xy rach 6 0 da iy C. Syethity phin GgP cin 3,3 Keal/mol DTrgyeei dug up tha vio be bch hay, glucose vl aid aminduge pth do dah mgch cla vi gan E. Tit ci déu ding & | }4. VE he sb cén bing phan img trong i CHUONG 8 CHUYEN HOA NANG LUQNG 1. Chon mét céu ding: A. Nang luong ty do cia mt chatting ki entropy ting. B. Ning luomg te do li phin ning haong 6 thé bin thin cng é ch. CC. Entropy phn én ning lugng toda pin cia chit. D. Trong hé kin, entropy gidm khi dé v6 tt ty cia hé thong tang. EE. Trong hé kin 6 diéu kién ty niga, entropy of Khuyn hung glam. 2. Chon mt edu ding: ‘A. Bidn thin ning Iugng ty do am néu ning luong ty do cia sin phim lim hon ning lugng tu do ca chit tam gia phin img, B. Bién thién nding long ty do durong thi phan tng phat ning, . Phin ing pt ng oh xay rat pt. . D. Bin thién ning lugng ti do phy thube vio con ding chuyén hoé cia phin ‘ing. E. Bidmthign nog ogng chun dug xe din & 0°. 3. Ve enthalpy, chon mt cu SAI: ‘A Entapy lini ning ca pct 3 Enthalpy lng lug ai png kh mt hep cht it eo “At chi” hod ici, C. Enthalpy duge sir dung toin b6 dé tgo cing c6 ich. D. Sw khéc bigt gitta enthalpy va nding luong ty do phy thude nhigt 4. E, Sq khéc biét gitta enthalpy vi ning lung ty do phy thude entropy. sinh ge (K”) AK ip tong tong fn BK’ ign quan den bed pin ing © K°> 1 ki tai trang th clin Bing, co chit thd gan phn mg nbidu hon sin him .Trong id kgachuin sinh hoc, K°> 1 thi pining thu ning , Trong iu kiga chudn sinh hoe, K? = 10 tuong mg wi AG,’ = 1,36 Kealino 5. Nhiét 6 trong diéw kign chun sink hoe duge dinh nga li: AoC B25°%C c30°C 37°C E.40°C %6; pH uong dibu ign chu sinh hoe age dich nha is Ao B60 ces D.10 E74 1. Cip nto KHONG vik theo tin cht oxi hoch i AFR B.RCOOH/RCHO c D.HI E, Pyruvatflactat 8. Chon mit iu ing ‘A. Trong bio, phn ting oxi ho ki xy ra lun kém theo sy pt ning B. HE thing oxi hod kh ct wing oxi hod itp cng 6 Kh ning dng va te cht ox bod. .Trong hg tng ox ho Kh, din td chuyén cht oxi bos én cht kh. D. Gitta 2 be tng oxi oko, din wr chayn hf thing ob thé nang oxi Pots sgh ing on rng oto th th. , Nang lugng tr phan ing oxi hot kh cha duge sit ding ngay va khong he duge ich 9. Chon mit eu SAK: Ce i tsa iy ink git ng lug A. Pyrophosphat B.Acylphosphat Est phosphat D.Thioeser EEnolposphat 10. Chon mi ci SAK: Ce i et sau itn kt ho ng mg ‘A. Glycosid B Peptié C. Carbonyl ester D. Este phosphat ‘E. Guanidin phosphat LL, Chait 6 ign Ket gidu nding fuwgng Li: ‘A. FracosIophospat B.13.Diphosphoglyerat . Adenasin monopbosphat D. Gycerol-phospat E, Glucose 6-phosphat 2 1)12, Nang lugmg (Keal/mol) gi phéng ra ki ATP bi thuy phan thin ADP (@ pite7, 25 "ola A103 B96 C86 D.73 £.66 13, Chon mét eiu BUNG: ‘A Litn kt gidu ning lugng trong di ben B.Litn kd phosphat rong AMP I ign kt, Lin kt ppt I link itu ning loop. '. Moe ign két ki bj thy phn gai png ra 6,6, tugng. E, Ning lugng ela mt lign tl ming lugmg dye gi png kh ia kt ny bi clit i. ing lugng. mo én kt go ning 14, Chon mst eu ing ‘A Phin ting phosphoryl dla phn ing thy ng. B, Phin img phosphory! hot to phosphat v8 cot do. CC. Phan tmg phosphoryl hod chuyén g6c phosphat tr chit ny sang chit khéc. D. Enzym glucose-6-phosphatase xiic téc phan img theo chiéu phosphory| hod. Phan img phosphor! hod khng thé ghép vi phn ing kh phosphoryl hod, 15. Chom mt cu SAI: Vai tr cia phan img phosphoryl hod ‘Tih ut ag hegng B.Cang op nlog ogee C. Hogt hod co chat D. Heat he enzym Eee eam 16. Chon pt cu ing: A. Qué trinh oxi hod trong té bao xy ra do oxi true tiép tic dung lén C va H cia bgp chit hove 8 ta COs v0. Chub hh fbi qu unk vn huyénnguyén i oxi qua mgt hbng cazym, C. Trong té bao, phan img khit carboxyl tao ra CO, tt oxi thé vio, Tong chu hp bio, 0 due to thin on ov, E. Chudi hé hip té bio xay ra chi yéu 6 bao tuong, 17, Ved hip té bo, chon chu SAI ‘A. Bin chit la qué tinh oxi hod Khir B, Ning lung giai png dn din ©. COs dupe to than do tke dung cia oxy Ién C ”1D, Nuée dupe tg thinh ti tée dung ete H’ vi O° Qué tinh van chuyén ep H pt sinh nhiéw nang lvong 16, Chon mt edu SAI: Cc yu tham gia chi hd hlpt bio A. Viarin © 1B. He thbng cytochrom . Oni phn th vo D. Enzyin dehydrogenase E.Ubiquinon 19, Chon mt cau SAI: Két qui cha chubi bb hp t& bio: A. Teo ning lugng. B. Teo COp €. Teo HO D. Tao FRO E.TqoO: 20, ‘Trong chubi bo hp tf bd, tsb phosphoryl hod (P/O) bing 3 nea i ‘A-THigtham gi gia phospho vA ox I 3:1 BT ham gia gia phospho vit oxi 13 nguyen tony dupe sit dyag th eb 3 ATP dge to thiah ‘D, 3 nguyén tir oxi duge sir dung thi o6 1 ATP duge tao than EE, Phusphoryl hod xy ra nhiéu hon 3 lan so véi oxi hod 21. Chon mgt ctu SAL: ‘A. Coenzym Q edn duge geil ubiquinon 'B Phan img #02 > HO + COs duge xic tic bai catalase CC. Phin img Khir carboxyl duge xi ta boi decarboxylase 1. Oxy la chit cubi cling nbgn dign trong chubi hd hip tf bao EE Glutathion tham gia chubi hd hip tf bio 22 Tein vn chuyén ign oa cde eytochrom trong chub No hp bo A.Crtaestaertberte B.Gitacstb areca C.Cyteestb cyt, stay D.Gtbota cya, cyte E-Opboste, yt aycytes 23 Cytochrom oxidase, chon chu SAL ‘A. Vin chayén din te ip tox th vo 'B. Nhém ngogi khéng chita sit C.Cé chin hin porphyrin ging hem D.Cé cong the . Lp hgp gdm cyt av yt in dt chat vi na 8 x 28 29 3024 Che enzym thm gia chub hd hip té blo, TRU: ‘A. Phosphorylase B. Peroxidase C. Superoxid dismutase D. Catalase E. Dehydrogenase 25. Che enzym cb vai tr ki tong co thé, TRU A. Hydtoproxidase B Peroxidase C Oxidase D. Catalase E Superoxid dismutase 26. Chqn mot cin ing ‘A. Si phi ghép to nit ning, B, Sy phi ghép kh eich v mat sib boc. Sup ghép lim ting chi sb phosphoryl ox hod 1. Oxi ng due tgp tye si dung ki csv ph ghép. ,Thiéu hormon tyén gid ety hign mg ph hep. 27. Chu tinh acid iti: ‘A. Khoi du tip chit c63 carbon. B, ay ra trong iysosom. C. Liha irinh thos hod ge trng cho gli D.Giaidogn 1 tgo thin iat 6 6C E, Xay ra trong du kign yém ks 28. Dic diém cia chu tinh acid citric: ‘A. Cé thé xay ra trong diéu kign yém khi B. Lagat dogn tod hod th I cia uci, lipid, prot CC. Vj te xy ra trong ti 1. Cé sutgo thin ec acd tricarboxylic E. Acid eitric cing gée acetyl két thie vi bi dl mot chu tinh 29, Trinh ty cée chit trong chu tinh acid citi: ‘A. Malt, succinat,citrat B. Cetoglutarat,isocitrat, oxaloacetat . Succinat, oxalosuccingt, isoctrat 1D. Fumarat, succinyl CoA, malat E, Citra, oxalosuecinat,fumarat ‘30, Dign bién va két qua cita chu trinh acid citric, chon cfu SAI: ‘A.2 phn tng kh carboxyl tgo 2 COs'B, 2 carbon oa gc acetyl di vio tgo oxaloaceat C.4.ebp H tgo a0 D. Teh ut duye 12 ATP . E. Dfe lip véi ee chuyén hod khic trong co thé 31. Trong chu tinh acid citric, NADILH’ hoe FADE, KHONG duge to ra & gi oes: A3 moo 32, Trong chu tinh acid eit, ATP duge igo ra khng cin qua chubi é hp té bio & pai doqn: ‘A. Isocitat—oxalosuccinat B.Succiyl CoA ~» sucinat C. Suosinat— fumarat . Fumarat ~+ malat E,a-Cetoglutarat > succinyl CoA 33, Trong m6tchu tinh acid cite: ‘A Hai carbon ca acetyl-CoA st dupe chuyén thin COp, B. Giai phing 2 phan ti CO. C. Gi png phn ti a0, D Teh 24 ATP. E. Tite ATP db Guye tg thin abo chub bo hip t€ bio. 34. Chon mit cfu SAl: Chu tinh asi etic: ‘A.Tao NADEH’ va ADE, B. Teo GIP. C.T90 C026 isi dogn chuyén malt thinh oxaoacetat 1. Cé sin phim trung gian la cic acid ticarboxylc. EE. Sin phim di vio ch trinh ké tép la oxaloacetat, 535. Chon mt edu SAI: Chu tinh acid cite lin hé véi chudi 6 hap té bio i ede gia dose: ‘A. Suecinat > fumarat B, a-Cetoglutarat > suesinyl-CoA C. Isocitrat > oxaloacetat D. Malat > oxaloacetat E.Citrat > cis-aconitat 36, S6 ATP b kh ning dupe to thin trong qu rinh vin chuyén cp H va fp di TENADELI ti ot Al wo 3 9moo 2 3 4 5 37. Trong chu trinh acid citi, s8 ATP c6 khi ning duge t9o thiah khi oxi hod succinat ‘thin fumarat, room 38, Céc tén goi sau du déu chi ciing mot chu trinh, NGOAT TRU: ‘A. Chu tinh acid trcarboxylic B. Cha tinh acid citric C. Chu tinh Krebs D. Chu tinh Uré Chu trinh TCA 39. Tip hop 6 chit tgo nhiéu ATP nbt trong qua trnh vn chuyén hiro vio chubi ho ptt bao AA. Acid citric, acid succinic B. Succinyl CoA, acid succinic C. Acid a-cetoglutari, acid fuarie D. Acid succinic, acid malic E, Acid isocitrc, acid malic 40. Chit ndo khong phi la chit chuyén hod trunggian trong chu tinh Krebs A. Pyruvat B, Oxaloacetat C. Oxalosuccinat D. Cis-aconita E. Malat 101CHUONG 9 CHUYEN HOA GLUCID 1. Swrphosphory!hoé co chit du tién trong qué tinh duémg phi: ‘A. Tyo san phim I 3-phosphoglycerat B. Teo ADP ti AMP C. Xie the bi glyceraldehyd-3-phosphat dehydrogenase . Xiic td boi phosphofiuctokinase E. Khéng dio nguge duge 2. V8 phan tng LDH, chon edu SAL: A. LDH chuyén pyruvat thanb lactat B. LDH chuyén NADH thanh NAD” C. Phan img than nghich 1. La phan ing eubi cing trong duimg phn yém Kh EEnzyzn duge tim thdy trong gan nhumg khéng o6 trong co 3. Vé dudng phan hiéu khi, chon eu SAI: ‘A Eazy kid sod a phogphorctokinase- B,D didu hoa qua 3 Khia .Xay ra trong bi wong oa bao ‘D, Tyo lactat va NAD" E_ Bat du véi glucokinase hay hexokinase 4, Enzym chuyén nhém phosphat thé vio frctose--phosphat trong dubng phn: ‘A. La phosphofructokinase-2 '. Xie te phn tng thufn nghich tong du kiga sinh I (C.Tgo sin phim fuctose-2,6-diphosphat 1. Kim sot qué tinh dung phn E. Tao sin phim ATP 5. V8 phosphofructokinase- chon edu SAL ‘A. Hoot hod bi citrat B, Ucché bai ATP (C:Hoat bod boi AMP . Hogt hos boi factose-2,6-diphosphat E.Laenzym dj lap ind 6, Tat ed nhig chit sau duge sin xuit & 8 bio co trong diéu kign yém kti, NGOAL TRU AATP 18 Pyrwat 402C. Lactat D. Acetyl CoA E.NADH 7. Mt ngubi lie mio eng thlythiéu ning lugng. Qua kgm tra, ngubi ta thy ta cia ‘gut nly chi 6 thé sir dung acid bo va acid amin dé b8 hap, vk té bio san salt ‘itu lactat hon binh thug. Gai thichthich hop nh cho tinh trang cia now nay, te ‘A. Ti thé thidu protein vén chuyén dua pyruvat qua mang ngodi ti thé 'B. Té bio khéng dua duye NADH ts ume phn vo trong thé €.TE bo hit enzym tong qu inh dug phn go pyravat Te bio kim khuydt cud vi chuyéa electron TE blo thi enzym lca debydrogenase 8. Trong chuyén hod yém khi pyravat duge chuyén thinh lacat. Qué tinh nly tg0 ra 1 A.NAD* BLATP FAD D.HO B, Acetyl CoA 9. Pyruvat kinase: ‘A. Host dong trong ci qua trinh dung phn va tin tao dung B. Ue cht bei fructose-1,6-diphosphat C. Duge didu hoa tién toi, D. Sirdung 1 ATP. E, Bit du giai dogn 3 cba duimg phn 10. Enzym chuyén phosphodiaceton thinh phosphoglyceraldehyd thude nhém: ‘A, Oxidoreductase B. Transferase Hydrolase D.Lyase E. Isomerase 11, $00 phan glucose gin "C dupe cung ep cho t6 bio to lactt. $6 phn tir ATP gin C due tao think tr phn tir elucose ny li Ao B.250 C500 D.750 E. 1000 12, Trin ty thich hop trong hd hp iu ki la A. Vin chuyén electron, chu tinh Krebs, acetyl-CoA, ding phn 103B, Dung phan, acetyl-Coa, chu trinh Krebs, vin chuyén electron Chu tinh Krebs, dung phn, via chuyén electron, acetyl-CoA D. Acetyl-CoA, vn chuyén electron, duroug phan, chu trinh Krebs E, Acetyl-CoA, duimg phan, chu trinh Krebs, vn chuyén electron 13, Trinh gy ede ei rung gian va enzym wong qué winh dung phate ‘A. Glacose-6-phosphat; Phosphofructokinase-1; Phosphoenolpyruvat; Glyceraldehyd-3-phosphat BB, Hexokinase; Phosphodioxyaceton; Fructose-6-phosphat; Glyceraldehyde-3- ‘phosphat CC. Glucose-6-phosphat; Glyceraldehyde-3-phosphat; Pyruvate kinase; Phosphoenolpyruvat . Glucose-6-phosphut; Phosphoffuctokinase-; Phosphoenolpyruvat; Frucose- 2,6-bisphosphat E, Hexokinese; Phosphofiuctokinase-1; Phosphodioxyaceton; Phosphoenoipyruvat 14, Eazym to ATP trong qué tinh duimg phi A. Hexokinase B. Glucokinase CC Phosphofructokinase-1 . 3-Phosphoglycerat kinase E, Glyceraldehyd-3-phosphate dehydrogenase 15. Cochét trong phan img thudn nghjch cla LDH, NGOAI TRU: A Lactate B. Pyruvate C.NADt D.NADH+8" EB. Phosphoenolpyruvate 16, Chit ch yéu ca va kh hich go cAMP dé Kch hich phn gi glycogen vtech ‘ng hep elycogen li: A. Epinephrine B. Calmodulin . Glueagon D Insulin E Glucose 17. Enzym déng vai uo quan rpg tong dibu hod dung het sau Bn ‘A. Glucokinase B. Glucose-6-phosphatase C. Phosphofructokinase D. Pyrvat kinase E,Glucose--phosphat dehydrogenase 1 2 2318. Che sr kia xdy ra trong qué tinh ‘20 phosphoenolpyruvat tr pyravat tron tin tao uing: A. Tigu thy CO, - B. Tigu thy phosphat v8 co C. Sit dung acetyl-CoA, D. Tao ATP Teo GTP 19. Vé chuyén hod glucose & ngudi: ‘A. Gan king thim glucose ki king o insulin Bebo pt fan va nfo thm tu do 4S; véi glucose do chit vin chuyén slucose de hifu ke nha C. Glucakinase gan phosphoryl hod glucose tb d cao trong moi ditu kin _D. MO ngodi gan tim glucose khi mit glucagon . Gan bin glucose ki glucose huyét thank bah thrbng, va gi ping glucose hi glucose huyét thank cao 20. Hai chit a sin phim chinh cia con dung pentose phosphat gm: A. NAD" vatribose B.NADH va glucose C. NADP* va ribose D. NADPH vi ribose E.NAD* va glucose 21, Giai doan cn ning lugng trong dung phi: ‘A. Glucokinase B, Lactat dehydrogenase CC. Phosphogiycerat kinase D. Pynivat kinase E. Phosphoglucoisomerase 22, Co chit chin cia tn tao dutmg la: ‘A Galactose B. Giycerol C. Glycogen D. Sucrose E. Mannitol 23. Mot dita tré bj ha ding huyét, gan to va dong mi & mt. Sinh tht gan cho thy té ‘bo gan ling dong glycogen qué mic. Bgnh cinh nay 6 thé do thigu enzyen: Accel, I-glucosidase B. c-l,1-galactosidase Carl 4-glucosidase D.a-l.4-galactosidase E.a-l,6-galactosidase 10524, Vaitrd cb glucagon: ‘A Kish tic ch telah aid Rich thic in ao dung Rich thich dng phan D. Kich thich con duimg pentose phosphat Kh hich bg hep alveouen 25, Nhin di 4-5 git s8 xd ra sy kin: ‘A. Gi AMP ving v8 tng thng hyp glycogen & gan Ting AMP ving vi thg li gi lycogen © gan . Gidm ning epinepbrine va tng li gil lyeogen gan D. Ting Ca™ cova gi i ii glycogen E, Gidm Ca 6 co vi gidam li giai glycogen 26, Say bea tn, glucose miu vio t bdo vi dy tH © dang glycogen, debit © gan ‘Chit cho phn tr glucose usu msi vio glycogen i ‘A. UDP-glucose-I-phosphat B. UDP-glucose C.UDP-glucose-6-phosphat D. Glucose-6-phosphat E, Ghucose-I-phosphat 27. Enzyme lign quan dén tng hop glycogen la: A. Amylo-(1,4 + 1,6)-transplycosidase ‘B. Phosphorylase CC. Phosphorylase kinase . Amylo-1,6-glucosidase EE. Glucose-6-phosphatase 28, Vé phosphorylase, chon cu SAL: ‘A. C6 coenzym la vitamin BI B, C62 dang: dang & hoat dug va dang b khng host €Ong Dang b td thank dang @ hi Khir phosphory! 1. Trang thdi host @ng hay khéng hoet dng lién quan én serin E, Li -glucosidase 29, Cie enzym tham gia qu trnh glycogen phan, chon céu SAL: 106 A.cel,6-plucosidase (val A}-glucantransferase E. Enzym oft nhanh ct Ey) 3 3%30. Vé qué tinh Ii gi glycogen: ‘AS11038 ge glucose duge gi phing dui dang glucos-t-phosphat B. 1/10 gb glucose duye gi pong dui dang glucose-6-phosphat Car, 6-glucosiase to glucose-l-phosphat D. Li gil glycogen dea eung cp glucose vio mu ki cla E. Phosphorylase hogt dng khi dén khoang 2 glucose tir ché phin nhénh 31s Ye glycogen synthase: ‘A. Dang acbn goi la dang D B. Dang D phu thuge vio ming db glucose-L-phosphat C. Host dng trong bdo dich D. Hoat ng king cin doan mbi E, Tao li ket 1-+6 52, V8 qui tinh bug hop alycogen: A. Glycogen syathase gin glucose két hep UDP vio glucose ts do B, Glycogen i dogn glycogen c6 vai tim méi C. Amylo-(1,4 + 1,6)-transglycosidase gin 1 glucose vo mach glycogen D. Khing sit dyng ATP. . . . . Khi cl, akim hydroxy! si tyosn li noi gin gb glucose di tién ci slycogen 33. Vé qué tinh tbag hop glycogen ir glucose, chon cdu SAI: A Glycogen synthase cn dug git UDP-alcose-yeoge anslucnylse B, Glucose ty do age phsptoy] hos tinh ghcose--phosat 6 ug phn hod thin une phosphst €. Glucose nde hot ho & dng UDP gcose D. Tein ty cde enzym Ih glucokinase, phosphoglacomutse, UDP glucose Pyrophosphorylase, glycogen synthase E. C6 sy tao thinh pyrophosphat vé cor 34 Hexoknase: ‘A. Hat dg chin ti gan B. Ai lye thip v6i glucose C.Ca thé phosphoryl hs lg in gucse D. Bj te ché boi glucose-6-phosphat E.C6Km cao 35, Glucokinase: ‘A. Chi hog ng ki ning d glvcose nf bio 6 bio cacao B, Hoat ng sau bia anf glucid €.C6 Vmax cao 1. Too difu kin cho co thu nbn glucose E.Cé Kmihép 10736. Qué trinh dng phn hod glucose-6-phosphat thinh fructose-6-phosphat trong dung pha: ‘A. Licqud tinh dbng pha ho aldose-cetose 'B. Xie te bai phosphoglucomuase C. Chit trunggian la ghucose-1.6-diphosphet 1. Latgiai oan king bis bube trong dutng phn E, Bnzym xi téeo6 gin nhém phosphat 37. Sb ATP tigu tba tong qué inh dung phén dén giai dogn tyo fucose] 6- diphosphat néu tinh tir glucose ty do la: Ao moos 1 2 3 4 38. Sé ATP tiéu tén trong qué trinh duémg phan dén giai dogn tgo fructese-1,6- 69, Gi in od tg soe hy yon sahimg chit sau, NGOAL TR A.Glycerol B. Fructose 6ephosphat C.Lactat D. Pyruvat E. Acid amin (64, Che enzymn cla tong qué tinh tan igo dung, NGOAL TRU: A. Pyruvat carboxylase BB. Phosphoenolpyruvat carboxykinase CC. Fructose-,6-diphosphatase D. Glucose-6-phosphatase E, Phosphofructokinase 165, Cle enzym ota qué trinh tn tao dung e6 trong bao dich, NGOAL TRU: ‘A. Pyruvat carboxylase, trong ti thé BB. Fructose-1,6-diphosphatase, trong i thé . Glucose-6-posphstase, tong ti thé D. Fructose-1,6-diphophatas, trong hat glycogen E Pyruvat carboxylase, trong hat glycogen 2 76. Dang hoat ding cia glycogen Ape phosphoryl hod; dang host #ing cia elycogen kG bi phosphoryT hod, mes ‘A. hydrolase; dehydrogenase = B. dehydrogenase; hydrolase C hydtolase;_semisynthase . phosphorylase; "synthase EB. synthase; phosphorylase 67. Vi phn Ii glycogen vi chuyén bof glucose: A. Glucose phospat i elycogen gan thing i vio ing pin B, Gucose-6-phosphat ti lycogen & cod ki vio mu C. Bio twang tf bio ca chia glucose . D. Su phn li glycogen va ding phn & gan thuime khdng duge hog! hod dng that Epinephrine te ché dung pin 6 co. 68. V8 eycogen, chon ct SAL ‘A. Chie ning cia glycogen & gan l 4 cu cp glucose cho mau kh chn B. Chit ning cin glycogen & co a dé cang cp ing ugg cho sco co C. Khi sy phan fi glycogen duge hogt hod 6 gan, sy dung phan thutmg bat haat D. Khi su pia li glyeogen dupe hoat hod & co, dng pin thang oat doe hing mt phn glucose te lycogen vio ma (69, Che si kign iy ra trong ting hgp glycogen & gan vico, NGOAL TRU: ‘A. Glucose vio té bio gan vi duge phosphoryl hod béi hexokinase dé to than _glucose-6-phosphat BB. Mdt enzym thue nhém isomerase Ia phosphoglucomutase chuyén glucose-6- ‘phosphat thinh glucose-1-phosphat C. Glucose-I-phosphat duge host hoi béi UDP-glucose pyrophosphorylase 40 UDP-glucose va PP v8 co _. Glucose chuyén ti UDP-glucose vio phn tt glycogen bei glycogen synthase EE. Glycogen synthase la enzym kiém soét 70. Che sr kign niy ravi gi glycogen & gan vi co, NGOAI TRU: ‘A. Glycogen phosphorylase dang host dng xe the phn ting phosphory-phin cit in két a1 -glucosid tong glycogen " 3. Ensym ct nhc x us ping thn phn ia Ado gluco ong slycogen ©: Glucose--phosphat due chuyén thin glucose-6phosphat bi ‘Phosphoglucomutase tee D. Glycogen phosphorylase host ding & dang kit phosphoryl E. Ning d glucose vi AMP cao dng vat i ya t ie soit qn tong 11371. Vé chuyén hod fructose: ‘A Fructose bi ug pin chim bon glucose BB. Phin lon chuyén hod theo dung fructose 6-phosphat Enzyme higu i fratokinase ‘D. Khéag sir dung dusge trong tg0 ning wong cho té bao ©. Fructose edn chuyén thanh glucose 4 duge hap thu niém mgc rut 72 Vi cuyén bo fate ‘A. Phy thuge vito insulin 3B. Kd py hue inslin nung hich ch ci nslin Tei qua phin ig phosphofrutokinse D.Hexokinase ey eao vied glucose va fucose E. Tiing fructose trong thite an din dén ting ding ké tng hop lipic 73. Bea khéng dung ngp lactose i truyén, chon cu SAI: ‘Dot retain 3. Ug frtt pspabo . Giy bp ung huyet ning D. Gay ving da E,Giy uy gan 74, Dye thu) tinh thé trong di tho dung ning a dott dong trong céc eu trie cba mit: A. Fructose B Sorbitol . Glucose D. Vitamin C E, Che thé ceton 75, Nguyén hin i hu qua ci bb tng galactose miu gbm, NGAI TRU: ‘A Do thu galactokinase B.Dothida gllactse--phospat wy! wanferase © Giy de thu tinh thé doling dong glacial, Gay tba huang gan E. Gay chim phat trién tim thiin 76. Sin psn eta con dung chuyén hod aid uronic 6 ngui gbm, NGOAA TRU: A Xylulose B Acid galacturonic C. Acid glucuronic D. Acid ascorbic E, Acid gulonie 77. Vé aldose reductase, chon cau SA A. Xiie th pin ing tg sorbitol m4B, Xi te phn ing tao galactito C Khng 6 thu tinh thé cn i D.C6 dh cit E. Tham gia chuyén glucose thinb fructose 78. Vb chuyén hd galactose trong eo thé, chon cfu SAL A. Galactose of thé of nguba abe tr lgctoe trong tuydn sta B. Galactose tham gia chu tgo glycoprotein, proteoglycan .C. Sy nhép galactose vio 18 bao khéng phy thude insulin D. Galactose king la thinh phn cin tit rong thie kn E Galactose 6 wrong thinh phn eta cerebrosid 79, Tang insulin mau dng vai td chink trong céc sy kign sau, NGOAI TRU: A. Det glucose & dang glycogen 6 gan vico B. Chuyén glucose thi treeylglycerol 6 gan vim mo CThu nn acid amin va tng hep protein ca vn . Thi dy dy tt lucose dé ding cung cp ning lug cho nto hi di .Kich thich vin chuyén glucose vio cu vi m6 mo 80. 0 gan va coli gidi glycogen c6 aking de diém sau, NGOAI TRU: ‘A. Insulin hot hod glycogen phosphorylase B, Tyo cdc glucose-I-phospat boi enzym glycogen phosphorylase C. Host ding ci glycosyl (4:4) wansferas ft nhénh . Hogt dng cia a, 6-ghucosidse go cdc glucose ty do E, Glycogen phosphorylase sidan phosphat co 15CHUONG 10 CHUYEN HOA LIPID | Phan img sau dy duge nic tie bi enzym: Phospholipid + H,0 -> Lysophospholipid + acid béo ‘A Lipase B. Amylase . Phosphoipase-A2 D.Reductwse ——_-E,Phospbolipase-D 2. Lipoprotein lipase 6 nhibu nhl A.Léngrugtnon —B.Gan €. Think mgch mia D-Ty thé E.Tyy tng 3, So vi thudt dig di, think phn no sau Aly tuomg tng vi lipoprotein: ALDL B.VLDL CHDL D.ApoB48 Apo Ad 4, Lipoprotein mio sau dy chi ge tbng hap 8 nut no: AVL B.LDL c.VLDL D.Chylomicron EC va ding ‘5, Trong phurong phép dign di, thnh phin ndo sau diy tong img voi HDL 6 phuong phi siga ly thn: ‘A.Chylomieron B. elipoprotcin_C. Pre-Blipoprotein D.orlipoprotsin Lipoprotein lipase 6. Thin phi lipid no sau Aly 6 nhidu tong chylomicron: ‘A-Phospholipid _B.Cholesterol__C, Trglyeerid nisin D. Triglycerd ngosi sinh E_ Acid béo ty do. 1. Thanh phn lipid no sau diy 06 nhidu trong LDL: ‘A.Phospholipid _B. Chylomicron . Trighyeerid D. Acid béo tudo E, Cholesterol ester hoa 8, Thinh phan lipid nao sau day c6 niéu trong HDL: ‘A-Phospholipid _B. Cholesterol do . Triglyerid D.Triglycedd Acid béo tr do 9. Think phn epoipoprotin nio sau day 6 trong chy lomieron: A Apo Ad B. Apo All C. Apo Bo, D.ApoB-100 -E.ApoD nN6 rt tr 4 18 19,10, Apoliporotein no sau cé trong VEDL va LDL: ‘A. Apo ALL B. Apo Ad C. Apo Bu D.ApoB-100 Apo D 11; Dua vio keh thus (¢uimg kinh) cia ec lol lipoprotein - huyét trong, hy chon tip bgp ding: ‘A.Chylomicron> LDL > VLDL > HDL B. Chylomicron > VLDL > LDL > HDL. C HDL >LDL> VLDL> chylomicron D. HDL > VLDL > LDL > chylomicron E.HDL > chylomicron > LDL> VLDL 12, Sau bia an khodng 2 gid, huydt trong dye ldo sy hin dign nbigu cia; A.Chylomicron —B. VLDL CLL D.HDL EDL. 13, Phan trung tim cia phén tir LDL chita nhiéu: ‘A. Triglycerid va Phospholipid B. Cholesterol ty do va Apo B-100 C. Triglyeerid va Apo B-100__D, Triglycerid va cholesterol ester hi Cholesterol ester héa vi phospholipid Tré li ei ed ht ti 14 én 16 cya vd cd bleu sa A.Chylomicron —B. VLDL CLL D.HDL 14, Trighycerd c6 nhitu abit trong... va it nhét trong. 15. Phospholipid 6 nhiéu nhét trong ... va it nhat trong . 16. Cholesterol 6 nbiéu nit trong... va it nhit trong 17, Men LCAT (Lecithin ~ Cholesterol Acyl Transferase)c6 trong: ‘A.Chylomicron —B.LDL C.VLDL DDL EDL 18, Téng hop cholesterol didn tn theo tht sa A. Acetyl CoA ~ mevalonet ~ lanosterol~ squalen ~ cholesterol B, Acetyl CoA ~ squalen ~ mevalonat — lanosterol cholesterol C. Acetyl CoA ~mevaonat~ squalen — lanosterol ~ cholesterol D. Lanosterol - mevalonat - squalen ~ cholesterol E. Acetyl CoA ~lanosterol -mevalonat ~ cholesterol 19. Sy ting hop cholesterol nfi sinh chju anh huémg ca enzym ndo sau dy: ‘A. Cholesterol esterase B. Cholesterol reductase CHMG CoA reductase D.HMG CoA synthetase Cholesterol kinase ur20. Cholesterol tid cht cia ce chit sau dy NGOAL TRU: ‘A.Aldoseron -B.Comtcosteron_C. Testosron D.ADH E Mobi mit 21. Cle ehdt sau diy lim ting tng hop cholesterol NGOAI TRU: ATasulin B.Ghucagon C734 78 D. Ting HMG CoA reductase An nbitu glucose 22. Vai deta i mt ‘A. Nb tong ha chit béo BGip bith sinh tan wong da mt Ting gt tinh ea eazy pase D.Nglnchia rtd tn cholesterol 6 dung mit Cle tn dau ding 23. Tap hop no sau dy i acid mt nguyén pt (duge tgo tinh tr gan ‘A. Acid tauracholic ~ acid glycocholic ~ acid lthocholic B, Acid deoxycholic ~ acid lthocholic . Acid taurochenodeoxycholic - acid lithocholic , Acid taurocholic~ acid plycochenodeoxycholic E, Acid deoxycholic ~ acid lithocholic 24, Diu mio sau dly ding cho testosteron: ‘AiQeetoon ——-B.Bearbon———C.2L carbon D.t7eubon E24 carbon 9 ho nPeo 25, Cong the sau dy 1a A.Progesteron——B. Consol CAltoseron ——_D. Testosteron E Esradiol 7 26,86 ATP teh tet aye tong qu tein Bony hoa oetadeeanoat i AB BSL co | EMG 27. Qua trinh B-oxy h6a din ra 6: ‘A.Bio tuong vitrong ty thé ——_-B. Bio tuong va ef ibuthe .Trong tu thé D.Trong thé E, Cle ytrén du ding 28, Cle enzym sau By tham gia qua tinh B-oxy hoa acd béo, NGOAL TRU: A Thiolase B. Dehydrogenase C. Hydratase D. Reductase E, Synthetase 18 & 3 3729, Sin phim eudi cig cia qu tinh B-oxy ha acid palmitic la: A Acetyl CoA ——_B. Propionyl CoA. NHI; D.Triglyeerid ECO, HO. 30. Th ceton dupe ting hop &: AGan B.Thin Tim DM Ey 31, Phin ing sau dy due the bi enzym: Ci-p-Ch COOH (Hs -CH-CH-COOH é ee: aon aD ‘A. Xdy ty abién B, Reductase C. Dehydrogenase D. Hydratase E. Symibetase 532. Qua trinh tbag hop acid béo chi yéu xy rad Gan B.MO mo C.Tythé—D.Ngodity thé E, Tidu thé 33. Bnzym nio sau dy thidu sé pay nén ting lipoprotein méu typeI ‘A. Cholesterase B.LPlipase ©. Reductase D. Dehydrogenase E Hyeronyase 34, Thin hin Uipidhuyét no sau yt ki tglpoprotein md type A Trglyoerd B.Cholesterat ©. Phosphotipia D. Acid bo edo E Thteatrén 35. Bénh Tangier 6 dj tinh nko sau dy: A Tang phospholipid B. Ting cholesterol Tang triglycerid D. Khéng ¢6 Blipoprotein miu E. Khong 6 a-lipoprotein méu 36, Phan tr nto sau day l tién chit cia phosphatidylcholine va sphingomyelin: ‘A. Phosphatidy! ethanolamin B. Acetylcholin . Glycerol -3~phosphat D. Uridin diphosphat glucose EE. Cytidin diphosphat cholin 37. Sinh ting hop 1,25-ihydroxycholecaleiferl xiy ra tai ‘A. Dati 7~ehydrocholesterot B, Gan tircholecaleiferol C. Thin tr 25-hydroxycholecaleiferol D. Rut tr cholecaleiferol E. Thin va tim. 19438, Cholesterol c6 thé la tién chit cia cdc chit sau diy NGOAL TRU: ‘A. Chenodeoxycholic acid B,1,25-dihydrocholecaeiferal CTestosteon D. Glyeochalic acid . Cholecystokinin 39. Nguén ning lugng chink sinh tng hop acid béo 6 gam duge cung cép ti ‘A Oxidhés acid glucuronic BO ha acetyl eoenzym A . Thiy phn glycogen D. Chu trinh Krebs E. HMP (Pentose phosphat pathway) 40, Sphingosin to thinh cée chit sau diy NGOAL TRU: A Lecithin B.Gangliozid Ceramic D.Cerebrozid —_E, Sphingomyelin 41. Bénh no sau diy c6 thé gay ting ceton méu: A.Tidu duimgdowy ——-B.Suy gan ning. Suy dinh dudug ning D. Ti ed cde y tren E.Chico Ava 42, Acid béo ndo sau dy khong ting hyp duye & ngubi A Acid oleic B. Acid palmitic C. Aca stearic D. Acid linoleic. Acid butyric 43. 0 dng vét htu nbd, lipid dy i dui dang: A. Cholesterol ester B.Phosphatid ——_C. Chylomicron 1D. Acid béo bin bac hia. Triglycerid “44. Thoth acid béothinh acetoacetyl CoA chi yéu xiy a AMomo B Rugt Lich, D. Thin E.Gan 45. Lipase ty 1a m@t enzym thy phin chit béo, né howt Ang nhu la mgt: A Peptide B, Esterase ©. Carbohydrase D. Dehydrogenase E. Oxidase 46. Thinh phin nao sau diy c6 trong phospholipid cia cephalin: A Ethanolamin —B, Inositol ©.Betain D.Sphingozin _E. KhOng phi cée chat ny. 47, Caiolipin duge ting hyp tir cdc chit: A.CDP ~diglycerid + a-glycero ~(P) B. TTP ~diglycerid + arglycero ~( C. UDP diglycerid + acid béo 120D, Che ¥ trtn déu ding E. Cle § trén du si, Tic cu 6 48 din ctu 52 td lat cua vo cde 6 He sa: ‘A Sphingozin B. Lecithin C. Phosphatidylethanolamin . Phosphatidyl inositol _E. S-adenosyl methionin 48...» tng hop ti CTP, phosphocthanolamin va digheria 49... thg hop ti palmityl CoA va serin 50,.... thag hop tr dighycerid va CDP cholin 51... .. sinh ting hop bit ngudn tir CDP, diglycerid niumg khOng theo con durong cita phosphatidy| serin 52... edn thidt cho sinb téng hop lecithin Tr lt eee $3 dn 56 cha vo ee lu sou on ‘oon " ® nmTré Ni cd edu te 37 dn 61 dua vo cde 36 lieu sau w ® ea te 00H oH 4 © © Go0H Ee Tri lt ede edu tr 62 dén 65 dua vio ede sb liu sau Hs he =O 20 OH of CS) co} 12 3 54 5s 56 31 se 58, , oT @ a 6.©: © @) 2) cholesterol id lithochotic acid deoxycholie lanosterol acid cholamic (cholanois) acid chenodeoxychoic «acid deoxycholic «acd lthocholic acid cholic aldosteron + progesteron testosteron «cortisol aTré Idi cde cu hd te 66 dén 70 dea va ede 36 ligu sau: ‘A. Lipoprotein ipase 8B. CTP (Cyn trphospbst) C.1=Deiydrostoleseral D.LDL EHDL 66, ‘Tin chit cia vitamin Ds. 67... Ch hi cho bg hop ein. 68, Yd ln trong huyét ong. (68... Tien chin gly xo va thi nach, 70... sss Cate ching xo va thinh mach 71. Chat ndo sau day lién két véi acid mat: ASein B. Acid glucuronic Acid eo D.Celeum E Glyein 72, Th i hing tinh hudug dub dy ing cho sy m8 td v8 td ceton NGOAI TRU: ‘8.6 06 thé tg thn sy sy di dong. B. Higndign cao trong tidu dung do tuy khing kid sod. C. Dug sit dng & gan trong tht gian di uy dah dung .N6 bao gbim aceton vi §-OH-bulyrat Co hd ai it rong ne tidu “73. Thby phan mt hin hop phosphoglycerid c6 thé thu duge eéc thinh phn sau: A. Serin B.Cholin C. Galactose D. Glyeeol E.Phosphat 74, Cle chit chuyén hou tung gian sau diy ién quan dén sinh ting bop trilyceid NGOAI TRU: A. Acyl CoA B.CDP-digleerid ——_C,Glycert-3- © D. Acid isophosphatidic E, Acid phosphatidic 75, UDP-galactose, serin, palmity!-CoA tham gia vio qua trinh ting hop: A.Cerebrozid B. Gangliozid . Sulfatid D. Tited cde chit wen B, Khng phii cdc cht trén. (Céu 76 ~ 70: Da vio hin ve dién dt lipoprotein sau dé tra 13 cho ede cu hot sau (A B,C, D lied cht dege ich ra dupe sau Ki dign di) 76, f= LP tuong img vii... A | Genaggesne}— ‘Diém xudt phat 77. Chylomiron tong ing vi. B | Guaseuey | Mienogpnas 78. oc LP tong ing vi... “mses > | Wensagtsy aa * 8 a ® 8 4 85 %. 8779, Pre «B= LP tuong ing véi 580, LDL c6 ti trong khodng: A.<1,006 B.> 1.210 €.1,006~1,210 D.1,006-- 1,063 E.1,063~1,210 81, Ce enzym sau day tham gia vio qu trnh P-oid ha acd béo NGOAL TRU A. Dehydrogenase B, Hydratase C. Thiolase D. Reductase E. Synthetase 82. B-exid hoa acd béo véi carboa Ie, khBag no cin enzym nao sau diy: A, 6*trans-4?*-cisrisomerase B.A” -is-4™ trans isomerase Ca cis-d*raneisomerase D.A%,7-cs-isomerase E. Hydratase va reductase 83, Hoi thé mai cetonkhi ndng d9 ceton mu ting: A> 100mg% —B.2 10mg% C.> 200mg% D.1000mg% E. 100g 84, Phe hop enzym tham gia qué tinh tng hop acid béo gdm... enzym AS BS 7 Ds BS 85, Hormon ndo sau dy tham gia qu trnh ech thy phn triglycerid > dilycerid: A Insulin B.Glucagon = C. ACTH D.sTH E.Epinephrin 86. Theo phi rg nly chit ch (-) X ls ATP AMPe __P.diesterase_ 5».anyp to x ‘A.Ceffein—B. Insulin C. Glucagon D.ACTH E.STH 87. Theo phan ing nay chit ting hogt © X li A.CaffeinB, Insulin ©. Glucagon D.ACTH E.STH 12588, Cap lipoprotein-huyét nto sau day cétéc dung nguge trong nguy eo tim mech: ‘A. Chylomieron va LDL B.Chylomicron va VLDL C.LDL va VLDL D.HDL vi chylomicron E.LDL vial. 89. Thanh phi lipid nao sau day e6 nhiéu trong LDL: A. Triglyeerid B. Acid béo ur do C. Cholesterol Phospholipid E, Tit ca cfc chit wen 90. Trong qué tinh tng hop cholesterol, cht no c6 thé ie ch HMG-CoA reducuse: A. Acid béo te do B. Phospholipid CTSH . Glucagon ET, T 91. Chylomicron duge ting hyp tt: AGan B Thin C.Rugt D-Phbi Etim ‘92. Lipoprotein ndo sau diy tang cao trong miu sau ba An 6 nhiu chit béo khong 2-3 sit A.HDL B.LDL c. VLDL, DDL E. Chylomicron 93. Cholesterol la tién chait cia cc chat sau day NGOAI TRU: ‘A. Aldosteron B. Testosteron C. Vitamin E D.Mudi mat E, Vitamin D 94, frony hod hoda ton acid capric (decanoic) sé cb duge sb ATP la: ATG BB c.80 D.82 EBL 126 9, 97 98 10¢ 10195, Ceton-ni ting ceo trong béohnio sau dy: A. Suy din dung ng B.Tidu dug ty do thie insulin . hin il mgty D.cic j trén du ding E.Chic6B ding 79. CAs hormon sau Gay kich hoe opt dng enzym triglycerid lipase NOOAL TRU: AGH BTSH C. Glucagon D.ACTH. E Insulin 97. Lipoprotein nao sau day ting cao trong r6i logn lipoprotein-huyét type I: ‘A. Chylomicron B.LDL C. VLDL D.HDL ok EE. Tit cd cde thinh phin trén du tng 98. Trong didu kign binh thumg, mu6i mét duge tgo think vi do thi ti: ‘A.Gan va phi B. Gan va rugt Rupe va thin D. Thin va rugt E. Gan vi thin 99. Qua trnh Proxy ho xy ra ATythé B.Nhin bio CVihé D. Bao tuong E. Ribosom 100. Acid béo king no (ban bio hoa) nio sau diy c6 thé ting hop 6 ngudi ‘A. Acid arachidonic B. Acid linolenic C. Acid linoleic D. Acid oleic E. Acid cervonie 101, $6 enzym tham gia qué tinh ting hop acid béo la At 127moos 102. Phospholipid e& ntiba tong: A. Chylomicron B.VLDL CLDL. D.DL EHDL 103, Ditu no sau dy ding Ki ni v8 cholesterol ester hia: ‘A. Gi ong suy tbo gen B, Chiém 1/3 lugmg cholesterol tod phi C:Chidm 28 lugng cholestrol tin phn D. Tang cao wong ed tring hyp sit dag mt EAvAC ding 104, Cholesterol c6 nhiéu trong: AHDL B.VLDL CL 1D. Chylomicron ELDL 105. Chit ndo sau dy lam gid hogt tinh cis HMG-CoA reductase: Insulin B.TSH Ct Dit. E, Glucagon 106, Apo BAY nit tong AHDL BLDL CL .Chylomicron E VLDL 107. Qué tinh Bony ha xy 186 AGan B Thin They 10 n ne U3D. Bio tuong E.Ribosom 108. Heparin o6 vai rd mio sau dy A.Bing miu 'B. Lam trong hut tong sau bta ano id chi béo Khir be & gan va thn 1D. Chéng d6ng mau E.CécyB vaD ding 109, Thnh phan lipid no sau day o6 nhiéu trong chylomicron: Ho, UL 112, 113, A. Acid béo te do B. Trighycerid ni sink Cholesterol . Phospholipid E. Triglycerid ngos sinh ‘Thanh phin lipid ndo sau diy c6 nhiéu trong HDL: A. Acid béo np do B Triglycerid C. Cholesterol D. Phospholipid E. Acid palmitic ‘Thanh phan lipid nio sau day c6 nhidu trong LDL: A. Acid béo ue do B. Trilycerid C. Cholesterol 1. Phospholipid E. Cephalin ‘Apo B100 c6 nhiéu trong lipoprotein no sau diy: ‘A Chylomicron BLL + CHDL DDL EVLDL Lipoprotein nao sau day cé kich thude kin ahit: ALDL BDL .Chylomiron DDL E. VLDL. 29114 Tong phuong pip sidu ly tm, chit no seu dy twong img vi pre--ipopotein: AVLDL B.LDL HDL BDL LS. Trong phuong phap dign di, chit ndo sau dy tuong tmg voi HDL: ‘A.Chylomicron B. orLipoprotein C.BeLipoprotein D. Pre BLipoprotein E. Protein 116, Cp lpoproten hyo uy 6 te dg ngs trong x0 va bg mach: A. Chylomiron vi alipoprotin C. elipoprotein va Blipoprotein D. Pre-B-ipoprotein vi lipoprotein EE, Pre-ipoprotein va chylomicron 117, Didu ndo sau day ding khi ni vé cholesterol: ‘A, Gan la eo quan duy nhit ting hop cholesterol B. Tign chit ca glucagon (C. Mang nda -OH tgi vi ti carbon sb 6. 1.13 lugng cholesterol ester hoa duge tong hop 6 rubt 2/3 lugng cholesterol ester hda due tng hop 6 gan 118, Digan sa dy ing Ki ni vé mui mat ‘A. Gan lca quan duy nt ng hop mui nt 3 lit ong cb mn © ip pt ct i ign rong de iu hic bdo i vag da tit tending 119, Bénh ly ndo sau day o6 thé gip néu ct bo ehi mt: ‘A. Mi la do hi sinh 16 A B. Kh teu a tong ba An c6 miu chit béo C. Nhil tuong héa chat béo 6 rapt kém D.Tétedy ten ding E.Chieb B vaC ding 130CHUONG 11 CHUYEN HOA ACID AMIN | Enzym no sau Gy thy phn itn kt pepid du tidn cia chibi plypepti A. Typsin B. Aminopeptidase C. Chymotrypsinogene D. Procarborypeptidase E, Dipeptidase ‘Sin phim chuyén héa acid amin dio thi ra trong nude tiéu a dng vit duéi dang: A. Acid urie B. Ammoniae C. Glutamin D. Creatinin E. Ue ‘Trong qua tinh to melanin tr tyrosin cin ¢6 enzyme nio tham gi: A. Tyrosin hydroxylase B. Dopa hydroxylase C. Diamin oxidase D. Peroxidase E. Catecholamin oxidase Cie ct su iy A Urecnat B. Acid formic ©. N.formiino ghtamat, D, L-Giutamat E. Leucin in phim chuyén hoa cia histidin, NGOAI TRU: (Qué tinh bién di alanin thin during duge gi és ‘A. Duong pin B. Tanto glucose C. KhirCO; oxy hée D. Khitamin oxy héa E. Phin gii glycogen ‘Amino acid ndo sau diy khng tham pia chu tein ur A. Asginin B. Citlin . Histidin 1D, Omithin E. Aspartat 7. Trong chu tinh ur, giai dogn ndo cin 6 sy tham gia ca ATP: A, Gisi dogn 1 va2 Bi. Gini dogn 1 va3 . Gini dogn 1 va D. Gisi dogn 3 va E, Gia dogn 4 vas 8, ‘Tap hop ndo c6 mat trong chu tinh wré: A. Cazbamyl ©, Omithin, Arpinin, Acetyl CoA B. Curbamy! ©, Omnithin, Citullin, L-Malat CC. Omithin, Citrullin, Arginosuecina, Arginin D. Carbamyl ©, Asparagine, Uré E, Furmarat, Malat, Oxaloacetat, Aspartat 9, Phuong tinh ting quét cia sy ting hop wré tsi gan: 2NHL, + COp + 3ATP + 28,0 > Ure +2ADP + AMP + 4Pyc NH + CO; + 3ATP + 2H,0 + Asp Ure + 2ADP + AMP + 4Pyc + Fumarat INH, + CO, + SADP > Urt + 3ATP +3 #0 NH) + CO; +2ATP + H,0- Ure + 2ADP + AMP + 2Pye ". Tit cd déu sai meoee 10, Acid amin khéng edn thiét durge co thé: 1, Tténg gp ma king cin cung ep theo dung de 2. Téng hop theo con dubng riéag ea ting acid amin, 3. Tag hap nba eds enzym rong pit bgp multienzym. 4A Téng hap duge tr ede u-ceto acid txong ing. Chon tap hop ing. 1 A134 B23.4 © 1,253. D124. E, Thted céc ctu wén ddu ding 11. Phan ing tgo a-cetoglutart ti L-glutamat dupe gis ‘A. Khir amin, B, Chuyén amin, C. Kh CO oxy hi, D. Thiy phin E, Khitamin oxy ha, 13212, Protein nto sau ddy khing bj enzym thiy phan trong éng tw héa: A. Myosin B. Globulin 1 © Keratin D. Serotonin E Feritin 13, Enterokinase hot héa enzyme ndo sau diy: A. Topsin B. Trypsinogen . Elasase D. Pepsin E. Pepsinogen 14, Transaminase trong phn img chuyén amin thug c6 nhiéu &: A. He ving mee ni mé B, Trong thé ty C. Bio dich D. Nhan tf bio E. Che mb ding vit 15. Trong gi dogntigu héa protein: ‘A. Cle enzym thiy phi tée dung c6 tinh fc higu d6i voi vi ti ea cde lin kés Se eee Sota ai Ong ct ‘D. Chiu tic dung cia cde enzym: pepsin, trypsin, chymotrypsin. ee E. Tit cé cde edu trén déu ding. 16, Trong chuyén hi cia L-yrosn' sto tinh hormon é te ng li tng hay 9 cht A. Acid vanyimandelic 17, Chom tp hop ec enzym thy pai itu hoa protein: 1. Pepsin 2 Lye, enaerse 3. ‘Trypsin, chymotrypsin 4. Hyde 5. Carboxypeptidese, aminopeptidase (Chon dp ha ing 1332, 3, 4 3, 3 moOR> 18. Chon tip top ding 1. Phin iru I sin phim tod he chinh apr 2 2 phin tu kt hp cho chat iat. 3. Phin tir uré e6 2 nhém -NHz, 1 nhém do carbamyl® cung dp, 1 nhém do -aspartat cung clip. 4. Ure de to thn ch yu 6 gan 5, Liga kt wong pi bi lin kami Chon céu ding: 19. Thy phan protein rong rupt: 1. Enzym entrokinas én i typinogen thi yin, , 2. Trong ‘khi hogt héa trypsinogen thinh trypsin thi enzym nay khdng c6 sy thay di vic hing inci ah Trypsin ld 1 chat c6 khd ning hogt héa chymotrypsinogen. . 4 Trypsin vi chymotrypsin khng th thy pin png thich acid amin cs chub otein ma pic te dng int én ca pepsin én poten othe Chon i ing A123 B13. C24 D. Cile64 ding E, Cl i Bu ding 20. Chon ding tn th tw ea ede cng tite sa diy: S a wot Pco0% cugncog! ung’ YAM em ES Y * wo @ @ 6 A. Tauri, 3,4-Dihydroxyphenylalanin (DOPA), Hydroxyprotin, Histamin, B. Hydroxyprolin, DOPA, Histamin, Taurin. C. DOPA, Histamin, Tauri, Hydroxyprolin 134D. Hydroxyprolin, DOPA, Turin, Histamin E. Taurin, Histamin, DOPA, Hydroxproiin. 21. Enzym pepsin: . 1 Tham gia qué trinh ty xictéc, vi ki o6 sy hign dign cia HC, pepsinogen ty bién dt thin pepsin iceman, 2. Te dung pH 1 dén 2, ct ce ign kt pep ia ce scid amino bin thon 3. Trong bén anemia pernicious, stiéu héa protein rong da day bj i6i han vi pH acid im dg diy King. di do gidm sin mult HCI nén King thich bgp cho host cia pepsin. 4, ‘Troms bh ci stig HL king ia i rong yw pen 6 mit cing king th tc dig teu ha protein de hon eu ding A123 B34 c243 D. Chies 4 ding E. Titcédéu ding. 22, Phenylketonura 1. La mit bgoh 1 ndu King due did te sm 9 hy dn di te om 2. Nguyén nhdn géy bénh do thiéu enzym phenyialany! hydroxylase bim sinh. 3, Bénh ly do co thé tgo ra qué nhieu tyrosin dehydroxylase, 4 Gite bj ben ly ndy,phenyalain khdng bién i thin tzesin, mph theo con ding chuyén ha py 90 ra phenyl pyruvat va due bi ta nue ew 23. Logi bé nhém amin cia céc acid amin 6 dong vat duge thir hign boi: ‘A Su thy gid vi pki amin, B. Chics tchuyén amin C Chuyds amin vi Kh amin oxy he. D. Cheb sy kh amin bia E. Khing e6 phan img nao. 24. Tit cd nhimg chit sau day la sin phim chuyén héa cita glycin, NGOAI TRU: A. Aeid onic B. Acid glyoxylic. . Acid formic D. CO, vak0, E, Acid benznic, BS25, Khi ammoniae duge truyéu qua gan ché, chit nao duge tgo ra: A ure B. Acid wie C. Glutarnin D. Xanthin 2B, Asparagin 26. Qué tinh kit amin oxy hoa eta acid amin xiy ra qua 2 bude, mt chit trung gian due tgo ral: A, @Cetoacid B. Ure . aelmin acid D. Acid uric E. Ghutamnin 27. Phin ng Xi CO> cd cid ann no say igor 1 ch Tam ds ech A. L-Glutamic acid B. L-Arginin| C. L-Asparte acid D. L-Valin E, L-Histdin 28. Phiin lén ammonia durge phéng thich ra 6 thén la tir acid amin nao sau day: A. Levcin B. Glutnin C. Glycin D. Alanin E. Asparagin 29, Acid amin en tit A. Co thé khing thé ting hop diy ii ma phi duge cung efip b&i thite an. B. Téng hop 6 thn nhumg khong duge tao ra 6 cde m6 khéc. c. ag de i i vt gl quan ang Ab co D. Buge bign duyg bbi men D-amino acid oxidase. E. Ging nhau trong tht cd ede loi dng vat c6 vi. 30, Trong no c6 1 enzym bién 4b acid glutamic thanh acid y-aminobutyrie va phin img ny di hoi sy hin dign cba chit nio sau diy: 136 A ATP BL Serin C. Carbon dioxide D. Pyridoxal phosphate E, Gluuamin 3 4 35 36 a731. Trong cde dng vét thai ra we, nhém carbaniy! duge chuyéa qua omithin dé 190 A. Pyrimidin B Ure c. D. Arginin E 3. Nhém methyl gin vao eystein tao thanh: A. Methionin B. Cystia . Ethanotamin D. Acid eysteic E. Cholin 34. Thyroxin (T) din xu tir A. Tyramin B. Taurin ©. Tryptamin D. Tyrosin E, Tryptophan 35, Allinism la bn bim sin do thiéw enzym: ‘A. Homogentisicase B. Phenylalany! hydroxylase C. Tyrosinase D. Tyrosin decerboxlase E. Dopa decarboxylase 36. Alkaptonuria la bénh Ibm sinh do thiéu enzym: A. Tyrosinase B. Phenylalanin hydroxylase C. Homogentsic acid oxidase D. DOPA decarboxylase E. DOPA oxidase 37. PhenyTketonuria la bénh li bim sinh do thiéu enzym dé: A. Khiramin cia phenylalanin 137B. Hydroxy héa phenylalanin Khir carboxsl cia phenylalanin D. Bin db tyrosin think DOPA E, Todhba rosin 38, Mot dog vt tinh trang can bing nitrogen (-) Ki: ‘A. An vio nhidu hom thi ra B. MO mei duge thank lip C. Tha vi in vio bing nhau D. Nude tiéu khong chita nitrogen E, Thre nhidu hon dn vio 39, Cong tite ct cde cit: ws A os manag! Bafa 1 2 Chon tip hop nto néu ding this cde ee te: A. Lysin, glutamin, omitin, arginin B. Glutamin, omithi,lysin, arginin CC. Orithin,arginin, lysine, glutamin D. Afginin, omithin lysin, glutamin E, Arginin, glutamin, omithin,lysin 40. The dng cia arginase trén cho ra ur: A, Glutamat B. Lysin C. Omithis Arginin Giutamin D. E 441, Acid amin no TA acid amin cin tit Aspartat Glutamin Omithin Lysin Pralin menee E 42, Acid amin no Ia acid amin khong cin thi: A. Isoleucin| 4 4Le B. Histidin . Phenylalanin D. Methionin E. Tyrosin - 43, Chit nto sau dly dgetgora tr phn img thiy phn arginin rong chu trinh wz: A. italia 5, Glutamin ©. Omithin D. Lysin E. Aspartat 44, NHs di chuyén trong miu du6i dang no: A. Pyruvat B. Asparagin C. -Cetoglutarat D. Glutamin E. Ammoniac 45. Chit no cho thly sy lin he gia bin dudng protid va glucid: A. Oxaloacetat B. a-Cetoglutarat . Aspartat D. Fumarat EB. Cid chit tren 46, Chit iol ct tung gian git 2 pining chuyén amin va kit amin: A. Pyrwat B. Furmarat ©. a-Cetoglutarat D. Giutamat E. Oralo acetat 47. Chon tip bgp ding: 1 2. 3 4 Hai phan img chuyén amin va khir amin c6 thé di di véi nhau. Phan img chuyén amin xiy a twong db dng, cdn phn tng Khir amin nay ra a hon Phin img chuyén amin do enzyme transaminase xe te Tit cd cde acid amin trong thién nién déu e6 thé thie hign dupe phan ng Chon tp hap ding ALD B. 24 Cc. 1,2,3 139D. Chi cb 4 di 2 dade 48. Hyperammonemia la bgoh bm sinh do thu: A. Neacetyl glutamat 'B. Onin carbamyl transferase . Carbamyl phosphat synthetase D. Arginase B. Catalase 49. Arginosuecinaciduria li 1 bénh bim sinh do thiéu enzym: ‘A. Carbamyl® synthetase B, Urease C. Arginin synthetase D. Catalase E, Peroxydase 50, Citrlineie: 1. LAI bnh bam sinh 2. Dothiduenzym arginosuecnat synbetse 3. Trigu chimg béah thutmg xuat hign 6 tré em 4 Gyr foan duh vi chim phat id tf kon 5 5. Lwgng ammoniac ting cao trong mau anh hurmg dén hé thin kinh gly chim phét sib te tug, 51. Bnzym no te dng et ign kt ppt & i Ct ca 1 chub polypeptid Decarbonyase Pepsin Maliase Casboxypeptidase KGhdng ob enzym ao kd én room 52, Vidt én cia enzym vi coenzym tic dung trong phan img sau dy: Legiuiamate =» c-lminoglutarate ¢=——> a-Cetoglutarat + NH) 3. Cau ghi: \Vidt cong thite cia phn tr uréndi 16 ngubn gdc 2 nvm NHI tong edng thie 140 54 5. 5654, Chu ghi hi phuong tinh ting quit cba sting hop uré 55. Cau gh Trong sy téng hop uré cin my phan tr nude (HO). Bé la giai dogn nio tong chu tinh ur 56. Chon tip hyp ding véo-eto aid 1, Cae acetoaid dupe tg thin nhi sy Khir amin oxy héa cc aid amin, 2 Cac a-cetoacd tng op duge cc acid amin sr chuyén ami bo amin héa. 3. Cle a-cetacid sau Ki Ki carboxyl sé chuyéa thin acl Béo bi vi ch tinh ‘Krebs, cudi ciing tao ra COs, HO va nding long. 4. Che o-cetoaidtuomg ing nim tén Gud tod be ca ch tinh Krebs 38 tng hp nén chit dung hay chit béo hose tod hda hain todn cho ra COs, FiO vi ning gg, Chom tip hap ding: ‘AL2 Bas ©. Chicds ding D233 E, Tited abu ding 57. Chon cfu ding: ‘A. Ning 46 uré huyét khéng phy thube vio ché 46 an wing, B, Néng dcreatininhuyét han pny tude vio ché da wing, CC. Trong suy thn, nig ure hay gm. D. Trong suy thio, ning 8 creatinin huytthanh gid. E Theed bu sa 58. Chon cu SAL: ‘A. Albumin chi yéu duge ting hop & gan. B, Phin én globulin duye tao Ghé ving mae nim. C. Globulin tham gi cu a0 khng the. . Phin in albumin va globulin dé duge to than 6 gan, E, Fibrinogen duge tg tinh & gan. 1459. Chon cu ding: ‘A. Uré duge tbag hap chi yéu gan, vi vay xét mghidon ure trong mu 06 gi i rit én tong vide dh gi chic ning gan, 'B, Tr} bind thudng cia uré huyét la 0,2-0,4 gid, C. GOT va GPT i eée enzym ngi bio of vai rd quan trong trong si chuyén héa cc acid amin v thé co gid ty Kn tong vige dah gia chos nang ehuyén toa rein tong gan. ; D. e-Cetoglatart vi ghutamat 18 céc chit trang gan host dng nw 1 con thoi ‘in chuyén dm arin, nbé dfs acid amin bu duge ki amin oxy bs E, Cie elu téa du sa 60, Alkeptonuria ta bf A. Céliéa quan dé chayda hu ca wyptopan B Xay ra do sy thiéu eazym homogentizat oxygenase tren dutng ‘chuyén boa ‘cia tryptophan. C. Do su thiéu enzym phenylalanin hydroxylase én duimg chuyén héa cia phenylalanin D, Do thiéu sic té melanin. . Khdng cu no ding 61. Chon elu ing: Cho phn ing: 1 -Glhtamat + a-iminogutart «+ a-Cetogutaat + NHs ‘A Phin tng niy duge nic tio boi enzym Leglutamate debydrogemse vb ‘coenzym NAD". ‘Diy It pin img ki amin oxy ha . Phin img xy ra qua gai doa, gsi dogn 2 khtng cn zy x th. D. Phi ng ny xy a pH cb co he E. Titea déu ding, 62. Trong 1 con vit binh thing, chit nu hujnh (S) cia methionin dui dang: A, Ester lin két B. Sultate vo eo . Sulfate hitw eo D. Sulfite E. Kh6ng 6 dang nio hit cystein cuge thi 63. Phan ing chuyén nhém amin ca acid amin duge wie th bai enzyme: A. Phosphatase B. Dehydrogenase C. Transaminase D. Oxygenase E, Thiokinase‘64. Tong céc phn img thoi héa acid amin ttting 06s hign dia eis coenzyn: A. NADY B. FAD C. NADP . Pyridoxal phosphate . NADPHH" 65. Trong chuyén hoa asd amin; ‘A. Sin phim do thi cia acid amin acc hop chit cia nto B. Thodi ha acd amin &nguti cho ur, CO 0. C. Cung cdp khodng 12% tng nang lugag co thé. D. Tgo think nhidu pho ti sinh ge quan tong E, Tited déu ding (66, Chon eb SAK: Trong gi doan itu hb protein: ‘A Tée dung ea cc enzym tn eh ivi vt cine iat peti B. Cé sy tham gia cia phan tir HO khi thity phan lién két peptid. ©. Cle enzym dite pia oi 3 1D. Cac peptidase va catepsin cing hoat dng manh 4é tiéu hoa protein thitc an. E, Phin lim ede enzym & dudi dang proenzym (tién thin enzym) khi clin méi ‘duge bién di thinh enzym host ding. ‘67. Trong chu trinh uré, ohém carbamy! duuge chuyén qua omithin 48 tgo ra: A. Arginin B. Pyrimidin © Gitrutin D. Arginosuecinat E. Purin 68, Tyrosin duge ting hop te A. Melanin B. Glutamat C. Phenylalanin D. Dopaguinon E. Phenylpyruvat (69. Chit nio sau dly khng phi la sin phim chuyén ha cia phenylalenin: ‘A. Dopamine B. Melanin . Tetralodothyroxin D. Serotonin E. Homogentisc acid 14370, L-Aspartet + a-cetogluarat +» oxaloacetat + I-glutarnat. Pan ng trén 9 stham gia ci: ‘A. ATP vi acetyl coenzyzn A. B, GPT va pyridoxal phosphate. C. Deaminase va pyridoxal phosphat, 1. Leglutamet aetydrogenace, E. GOT va pyridoxal phosphat 71, Phan img sau diy clin sy tham gia cia: L-glutamat + NH) L-glutamin + HO ‘A. NADP va oxygenase B. PAD vi acid amin oxygenase C. NAD vi L-glutamat dehydrogenase D. ATP vi glatamin synthetase EB. Ton Mg™ va dehydrogenase ‘2. Chon tip hop edu ding: 2 3 4 5. Hai qd trnh Kv chy amin in quan ci i i nau, hc ad amin déu duge kit amin. ‘Tét ci acid amin déu duge true tip khir amin oxy héa. Glutamat duge kt amin tye tiép dB ding nho host dag menh cia enzyia L~ ‘lutamat dehy drogenase vi coenzym NAD. ‘Troug co thé dng vét, cdc enzym khit amin oxy ha cé hogt tin nh nha va sin phim to thinh sau qué tinh xi tc la u-cetoacid va NHs. GPT hay alanin transaminase la enzym npi bio s& ting rit 16 tong méu tong bh viém gan siu vi Chon tdp hap ding: AL? BL, c2, 1 3 3, 3, Dna E34, 7, Cle ch 6 hi ning vdn chuyén NH, tong nu: A. Glutamin B. Acid glutamic C. Asparagin D. Aspartic E. a@-Cetoglutarat 74. Sin phim itu he cia ed polypepid this And da diy li: A. Acid amin B. Oligopeptid ©. Protid n 80D. Polypeptid, proteose, peptone E, Khong cfu ndo ding 76, Tir ktuung carbon a-cetoglutarat,c6 thé tao ra duge acid amin nao sau dy A. Prolin 178. Creatnin ls A. Kho ditt ning lrgng thi hai cia co thé BB. La sin phim cia chuyén héa glutathion CC. La sin phim kh nude cia ereatin DB 8 gan E, Sin phim cia thos héa glycoprotein 79. Chon edu ding A. Creatin la sin phim duge tao ra @ thin BB. Khong 1,5% creatinthodi ha méi ngay CC. Creatin phosphate duge tao ra trong bio nrong cia tf bio D. Creatin phosphate duge tora trong ty thé eta bdo E. Khing céu nio ding 80, Béah nhuoe gdp bim sinh: ‘A. C6 thé duye phit ign nhs sing loc so sinh, ly mu méu kh tr mgdy tht 3 dt ngiy thi S sau sinh 3 Cot png nga due i iy i armon tay hs CC. Ta sut bah tr thé gigi 18500 dén 15000 D. Neu duge dda sm, téniuomg sit E, Cle edu én db ding 145CHUONG 12 CHUYEN HOA HEMOGLOBIN 1. chs tu aang: A Bin tng, nndng 49 bilirubin true tiép trong huyét thanh cao hom ning 45 iain gin ip B we 48 bilirubin toin phn trong huyét thank ngui binh thug 1: 0,05 — C. Khi bilirubin ty do cao trong mu sé duge dio thi qua née tid. 1D. Ving nim mac va ving da bit du xuat hin trong trgmg bap bb khi ‘bilirubin ton phn ln hon 20 mg. . Bilirubin tc tgp kh di chuyén trong mau phi két hop v6i albumin, Tyee sé nhimg tnzing hep beak Ij sau gly ving da, bfnh nio gly ting bilirbin rue A. Séurit. B. Truyén nhl abd md. ©. Themit D. Thidu Gop. Ving da dothiéuenzym gucuronyl transferase 3. Bilirubin yg do 1 bilirubin: A, Tan rong muse. BB. Cho phan ig diazo nhan, CC. Két hgp véi albumin khi di chuyén trong edu, D. Tao sic té mau ving cho nude teu E. Khong die. 4. Chon cf ding: 'A, Trong truing hop tic mit, bilirubin liga hyp ting tong mtu va urcilinogen tng trong nuée tiéu. BO gan, bilirubin trve tgp dug tgothinh tb bilirubin gn iép nh he thing men lign hop. . CC Trong ving da do tryén nhim nhém mu, bilirubin toan pin ting vit cb she 15 mit ong nue tia. . . Khi bilirubin ty doting ea0 trong mu sé duge dio thi theo dong du. E. Ki bilirubin lién hop ting cao trong méu sé lén nfo qua hing rho mau nfo ‘e8y ving da ain, 5. Chan céu ding: A. Bilirubin ty do 1a bilirubin trye tigp. B. Bilin kh lab gin ip. Bilirubin y do dug go tinh & gn D, Bilrbin re ipsa hide go thin hb xubng rut theo dng mit. E- Hon St ilirbin tp de ti lp thu theo nk mach a 6. Nong dé binh thuing cia bilirubin todn phn trong huy&t thank A. <10mgi B. <1 mg/dl Cc 10mg’ C. Gay vigm khep ep, dau ne dtd. D. Git aid uri trong mu. E. Céthdttdong san ust hoi an cle thin. Chon cfu ding: ARN polymerase ‘A. Xie the stb hap ADN. B. Xie te gin ARN! vo ribosom, . Xie te sob hap ARN D. Chuyén ARNtthinh ARN, E. Xe th siting hap ARN mb ‘Trong si nbn 461 ADN, enzym ndo sau diy o6 tac dung wie the sto ARN mi? ‘A. ARN polymerase, 1B. Transcriptase ngug. 183C. Helicase. D, Pras. E. King o6enzym nto kb én, 7, Boan Okazaki: ‘a nbing down ARN mb [Lanhng dogn ADN ngin tham gia to si sau a nhtng doan ADN [hahngdogn ADN gs tng by he chit 3° 5. [Laing pin tr ARN bé sung cia ADN, mooRP 8. Chon gu SAL: Téng bgp ARN ‘A. Dya trén khudo 1d mot sgi ADN cé sia B. C6 ARN polymerase xi ti. C, Dua vio nguyén ly bé sung déi base. D. Cin ATP, TTP, CIP, GTP. E, Xay ratheo chiéu 5*+3', 9, Phim img PCR: ‘A, Laphin fog polymerase chin reaction 3 Sig mm fag DNA mens rong opin ne C. Sit dung mot cp moi dae higu, D. Gi akong ial doen bin tah, bt cap v8 Ako di duye Ip ip qua mie ci Tit ie cate db ing 10, Té blo nhin tht 6 bao niu loai ARN polymerase’? A. Moai B. 2loai ©. 3 ogi D. 4 loai E. Sogi 11, Sia phim chinh eta sy thodi hod cytosin 6 ngudi la A, Xanthin B. Hypoxanthin © Ue D. Acid uric E, CO; vaNHs 12. Chon céu ding: A. Acid urie lé sin phim thodi hoa ca base pyrimidin, BG ngubi bi dmg, ong nde da dng 6 acid C. Tong ben gt, acid ure miu thug c20 hem 10 metD. Bénh git ply dau nhc din hinh 6 6 sng, E. B-Alanin la tién chit cia acid uric, "5. Nang pnt lo su dy vin ngun ec ce ngwtn tong ain prin va gun ab ea kc nguyen tong ni ya OME A A. Glyn, Ns formyltetahydoflt B. Ghutamin, 0s appara C. Glycin, methionin. D. Aspaayslain, E. Ni CO; 14. Trong sy nhén 46i ADN, enzym nio sau Aly téch r8i2 soi ADN va lim di ehuyéa hac ba: A. ADN gyrase B. ADN ligase. CC. ADN polymerase D. Helicase. . Khdng 6 chit no ké tr, 15. Enzym no sau dy kg tam gia vio shin 461 ADN: ‘A. ADN polymerase B. Ligase. . Primase D. Helicase E. ARN polymerase 16. Chom cia ding: Tron sy nbn 431 ADN: ‘A. Protein gin ADN soi dom (SSB protein) li mgt enzym tham gia qué tinh ny BB ADN polymerase Il chza 6 vai tr gi ring. C. ADN polymerase I khéng phai la enzym tham gia sira chta ADN. D, VBS do ml hing ce aes E, Soi din duvetbng hap theo chiéu S* — 3° cin soi sau thl de tbng hyp theo ehidu 3 9 17. Céc yéu t6 sau diy déu hign dign trong sy nhin dai ADN, NGOAI TRU: A. ARN mii. BUT. C. Transcriptase. D. ADN ligase. E. Dogn Okazaki '8.Chon tip hop ding: Céc sin phim trang gian duge to thinh trong ting hop pyrimidin nucleoid li 1. Carbamyl phosphat. 2. Dilhydro uracil 135moObPe i SRoRES 19. Chon tp hg dng: rong sy nn dBi ADN: a L 2. 3 4 5 “Teng hap 2 svi ADN méi nhs ARN polymerase Pratt gin ADN spi don (SSB protein) 6 ahifm vu git cho 2 syi ADN don & ‘rag th haw. Prime xi te sv go ARN mb ADN polymerase I lai ARN mdi 20, Sn psn chuyda hod ubi cing cia base pin & rgubi King phi bu wl enzym amin oxidase Kkngchuyén bod xa thin wrt ‘A. Ca? vi dbu ding vi vé2 Kg ii thich v8 1 B. C42 vé bu ding va v2 gi hich vé 1. C. VE 1 ding, vé2 si D. VE si vé2 ding E Ch véddusi 21. Enzym transcriptase xic tie sy ting hop ADN bé sung dua trén Khun la phén ti "ARN vit yl anserptsehign din & mot vit gy ung th ep C42 v4 db ding va vé 2 king gid thich v8 1 Ca 2 vé ddu diing va vé 2 giai thich vé 1. ‘V1 ding, vé 2 sai. V6) sai, vé2 ding ca 2vé abu si ree (Cau ho én yd 22, Nguyéa liu dé tng gp acid nucleic a 156 A B c x n 28 2» 30 a 2 33.25. Ligt ke 3 acid amin tham gia cung clp cle nguyén tr cia pnt puri: A B c - eet mbt sid amin cang cp mgt sd nguyen st tong phn i purn. Cc nguyen tir ts A B. c. 25, Cie nguyén tr trén phn tt pyrimidin o6 nguén g6e ti: A B. c 26, Vit tn hai chit trang gian trong qué trinhthodi hod aden: A B 27. Phan tr cung cdp nguyen ti NI trong nh purin la: 28. Phan tit cung cép nguyén tt C2 trong nin purin la: 29. Phin tir cung cp nguyén tiN3 trong nin purin a: 30. Phin tr cung cp nguyén tir C4 trong nbn purin la: 31. Vigttén 4 logi deoxyribonucleosid triphospht tham gia ting hop ADN: A B. c. D. 32. Sy thoi hod base purin s& cho ra sin phim la (A), 6 ngudi vi (B) G8 loi bd sit, mgt sb dng vit c6 vi vi nhuyn the 33.Su ting hop ARN dupe xie tic bi enzym (A)..-ctl ing nguyen ligu la ). lin de ch i chon rt ing ce cu hi 3437 ‘A, Hypoxantin B. Acid ort . Diydro rai, D. S-phosphoribosyl-t-pyrophosphat (PRP) 13734, Chit chuyéa hod trang gan hin din rong qué trinh thod hod adenin: 35. Chit chuyén hod trang gan hin dig rong qu in thoi hod eytsin: 36, Ct chuyén ho trang gia hin dgn wong qué tinh tg bop purn: a 37. Chit ehuyén hod ing gian hign din tong qué trinh tng hop pyrimidin: ‘Sit dung inh sau dé tri (0 ede edu 38-40 ‘Acid nucleic (ADN, ARN) #0 en Nucleotis a (39) Pre ‘Nucleosid “ | Base N + Penose ‘ 38 8... s 4. Sing hin sau 4 rh eee 4,42 wy amin oxidase 5 Guarin Xanthin——— (42) (0 401 41 a 40 Binh hg, ng eid ric wong mu kody 3060 mp%. Stee 5 B. Su 44, Acid uric mau Ki 6 nbng db cao sé ng dud dang tinh thé gly vit Kid ep ‘hofe soi dudng tiéu, A. Ding le B. Sai 15845, Adenase Ia mbt trong ning enzyta thar a qué trnh thoi ho base pyrmiin, A. Ding B. Sai 45. PREP synthetase ld mot trong nhitg enzym tham gia qué trinh ting hop base purin, 47, Dihydro uracil la m6t trong nhtng san phim trang gian ciia si thodi hod cytosin. A. Ding B. Sai 48, Helicase la mgt rong nhiing enzym tham gia qua tinh ting hop ARN, A. Ding B 49. Cé it nhét 20 enzym va yéu tb protein tham gia sy nhiin déi cia ADN. A. Ding B. Sai 50. ARN polymerase e6 tic dung tgo ARN mi A. Ding B. Sai 51. Sy tng hop ARN xiy A. Ding B. Sai 52. Protein gin ADN git cho 2 soi ADN dom 6 trang thi tich roi nhau va bdo vé phn tt ‘ADN khiéi bj tic dung ola ADNase, A. Ding B Si 53. ADN polymerase Il xc tc sy gin di tng ribonuceotid vio du 3 esp A. Bing Bsa ‘54. ADN polymerase I 6 vai tr quan trong trong sy sia cha ADN. A. Bing B. Sai 55. Chon edu SAI: ‘A. Téng hop ARN dia tén khun lt mit soi ADN o8 sin 159'B, Téng hop ARN c&n m6t dogn mbi la ARN moi. (C, Téng bop ARN dya vio nguyén iy bb sung di base. D. ARN polymerase king 6 ta dung ty sta cha E, Téng hop ARN xiy ra theo chigu 5* — 3 56, TE bio ntsc c6 bao nhiéu logi ARN polymerase: Al poor 57. Mt bah nh 4 toi ap vign vi thida mu vb chm In, Xétnghigm cho tiy aid orotic cao trong nude ttn, thiéu men ortat phosphoribosylinnsferase vi hogt th ten apart transarbamylase tng cao. Phuong php dig tno sau dy thich bgp: A. Toyama BL Truyén bych edu C. Bé sung PREP trong ché da, D. Ung thymidin. E. Ubog win, 58 Bibuno sau iy KHONG BUNG vi beh gi? ‘A. 0 dng acid ure cic khép. B. Ning 4 ur wong méu tng > 10 mg% . Gy vem kop fp, dau ne di D, Cén go a béa tg phong, , E. COthbiedgng sam urat thin hy 01 dung eu 59, Allopurinol dit ri ba git hu qui, nung Iai Khong ote dung tong hi ching Tesch-Njban, me ded hai bénh ay déu 6 ing puri. Nguyén nin la do ong Bi ching Leset-Nyhan allopurinol Khng c6 te dung nko san diy A Lim gim sin xu prin B, Lam gidm sin xudtpyrimidin , Lim itm tng hop acid wc D, Tang ivong PRFP. E, Ue ch xamhin oxidase. 60, Acid ure miu ting khOng gp trong traimg hop ndo sau day’ ‘A. Hii chimg Lesch Nyhan, B. Git CC Tang hoat tinh men xanthin oxidase D. men ting bap carbamy/ phosphat E. Béah Von Gierke, 160 661. Sy chuydn ma (transcription) 6 bdo nhan so xiy ra 6: A. Bio tromg. BL Nhin, ©. Ty thé, D. Bj miy Golgi E. Thtoa déu sa (62, Phin tir ndo sau dy cung cp nguyén tN cho ci ving purin va pysimidin: A. Aspariat B. Carbamyl phosphat © Cop D. Ghutamin E. Tetrahydrofolat 63. Chon edu diing nhit vé xanthin: A. Latin chdt cia guanin, B. Khi oxi hd tao acid uri. C. Lin két dng hod tj véi allopurinol. 'D. Chi l.co chit, khong phai sin phim cia men xanthin oxidase. EE. Khi oxi hod s8 tao thinh hypoxanthin 64. Neuyén nin mio sau dy 6 hee ch nguce lens tbng hop pyrimidin: ‘A. Tang hot tinh men carbamyl phosphat syntetase. B. Ting hogt tinh men agpatt ranscarbamlase . Tic dng i cht dip thé cba CTP D, Tée dung te ché canh tranh cia UMP. . Tae dang Ge ché ap thé ca TTP. 65, Chit mo sau diy 6 he ng ech sinh tg gp puri: A. Guanosi tiphospbat (GTP). Usdin monophosphat (UMP) C. Adenosin monophoepat (AMP) . Adenosin eiphosphat (ATP) E. losin dphospbat (DP) 66, Trong qué trnh ting hop pyrimidin, chit ndo sau day la ibn chit cho sy tong hyp 2 ‘mucleoid kh A. Cytidin triphosphat (CTP). B. Uridin monophosphat (UMP) €. Deoxythymidin monophosphat (ATMP), D. Adenosin triphosphat (ATP), E. Deoxyadenosin monophosphat (1AMP), 16167, Chit no sau dy 18 mptco chit cn thiét cho qué tinh sinh tbng hp puri S-Methy!thymidin Arc. Ribose poophat 5-Phosphorboslpyrophosphat (PRDP). 5-Rvorourac Fp OEP 68. Chit ndo sau day o6 tie dng te ché cgnh tranh véi hypoxanthin: A. AC. B. Allopurinl, CC. Ribose phosphat. 1D. S-Phosphoribosylpyrophosphat (PRPP). E, 5-Fluorouracil| 69. Usidindiphosphat (UDP) c6 ln dt chat che v6: A, Electron B. Phosphoryl ©. Acyl D. Aldebyd. E. Glucose, ‘Sit dung hinh v8 saw 8 tr 16i ede edu 70, 72 oo ae eee he ~~ my 1 ey 70. 1 72 Cong thi ny oH H A. Adenin c B Guanin “oth ©. Gyosn ‘D. Alantoin. Hes ae B. allopri 773, Sq chuyén mi (transcription) @ 18 bio nbn te ny ra A. Bio tuong. B. Nh ©. Ty thé 182D. B9 may Golgi E, Tatcé du sai. 74, Su gi mi (ranslation) od A, Bio tuong B. Nhin, ty tha D, Bp mAy Golgi, E. Cio trong nhin va bio tuong. io niin tht xy em 6 175. © té bio nhan thi, cae tién ARNT c6 thé tri qua mt s6 diéu chinh &é chuyén thin ARNt trugng thinh, NGOAT TRU A. Cit mt chuBi & dan 5°, B. Cit ni losi ba intron. C. Diu chinh mgt 6 base. D. Thay thé UU 6 diu 3° bing CCA. E. Citnbi ogi bd exon. 176, Enzym nao sau diy o6 tée dung tring hop céc deoxyribonucleotid tg thanh phan ti ADN: A. Primase D. ARN polymerase I B. ADN ligase. E, Reverse transeripase. C. ADN gyrase 77. Qué trinh thoai hoa pyrimidin chi yéu xi ra 6: A Gan, D. Thin, B Lich, E. Rope . Tuy xuong. 78. Trong qué tinh ting hop ARN, mbi polymerase gin vio ADN thio xoin mét doan ‘tog tng vi: “A. 6 di base 1.33 46% base B. 164i base, E, 346i base, C. 17 €6i base, 79. Chit nto sau dy 66 tde dung te ché men xanthin oxidase ‘A. Alloparinol D.Uracit B. Inosin E, Cytidin triphosphat (CTP). C. Acid orotic 80. Khang sinh ndo sau dy e6 tic dung ie ché qu tinh chuyén ma: A. Tetracylin D. Eqythromycin. B. Rifamycin. E. Chloramphenicol : Streptomycin, 163CHUONG 14 SINH TONG HOP PROTEIN ( HOL BIEN CUOL CAU LIBT KE): 1 Bom vj hogt dag cia ADN la tp hgp eta ede gen: A B. c. Ligt ké 3 ma két thie: A B © 3. Dya vio tir dién ma di truyén, cho biét acid amin nio tuong img voi cae ma (A) GCG, (B) CAC, (©) GOW. A c 4. Qué winh A B hign gen gin chai gi dogn: 5, Ligtké 3 giai dogn eda sy tng hop protein 6 Ribosom: A B c. 6. Ligtké ode yéu 6 chinh tham gia qué tinh sinh tong hop protein & ribosor: moepP 1. CAU OL BIEN CHO TRONG GIA CAU: 7, Protein duge bidu ita te sy sao chép (A)...othinh B)....vA sau 46 (B).......duuge gidi mA 4€ tgo thanih (C). 1645 ati chan srg bp (4). wn Abn (B.. ah rm 9. Qué trinh sao chép nguge 6 mot s6 virus ga thu 6 mo, la Ghandi nn bps rane mney oe ip peer 10, Gen cfu tr eis té bao 06 nh e6 nhitng dogn ml hoa goi ld (A)... va o6 nha doan khéng mé hda goi ld (B).......xép xen k8 nau. LU. Sau dy 1a mot 98 acid amin cy thé va ma trong img trén ARNm. Hay cho biét céc ‘hog tn uy (nl) ong ing a gs: ARN _UUCGGCGeGuGUCGAGUA Acid amin Phe - Gly - Ala-Cys— Arg- Val. II BIEN HINH SO BO: 12. Su thdng tn di tray 6 8 bio 66 nhin, Hay didn cht vio cub hinh sau diy mone 1651V.CAU HOI DUNG - SAL: ‘Tis cau 13 dén cau 24, ghi (BD) cho cau diing, (S) cho cdw sai vao bang 6 cudi edu 24: 13, Mam diu fa AUG, 14 Transcriptase nguge xc tée sy tbng hyp ARN dya trén khuén la ADN. 15, Protein ec higu duc ting hop diya trén Khuda ARNm nhéy qué trinh chuyén m8. 16. ARN polymerase xtc téc sy gin din céc ribonucleoti dyatrén khudn la gen ci tric ‘uum ting, to nén phn tt lai ADN ~ ARN. 17. ARNt dong vai trd vin chuyén acid amin va doc ma, 18. Si hogt hoa va vn chuyén acid amin duge xtc tie béi enzym amino acyl — ARNE — ‘syathetase 19, Chidu dge mi xay ra theo chiéu 3° 5° 20. Oé bio of nba, acid amin md du cho sy thag bop protein la threonin. 21. Trong giai dogn mi iu eta sinh tng hyp Protein & E. coll, ARN gin véi R SOS ‘nab, sau d6 R 30S méi tham gia, 2. Két qua cia giaidoan md du i pte hop mo du 70S gin vei yéu tb mb du IF. 23. Bube 1 cia gia dogn kéo dai chubi polypeptid la sy gin amino acyl — ARNt vio vi te P. 24, Erythromycin cd tie dung ngtn can sy chuyén vi, te ché a sinh ung hop protein & vik, V. CAU HOI CHON: 25. MB no sau dy Lama mi i? A. UGA. B.UAA, c. GUA, D. AUG. E. AGU. 26. Mino IA mi Két thie: A. UGA, B AGU, c. WA D. GAU. E. cau, 1627. Quit trinh chuyén ma: A B Lay ting bop ADN. ‘Cé enzyme tham gia la ADN polymerase. C. Xéy ra sau qué tinh sao chép. D. Xéy ra dya tén khusa Id ADN. E ‘Tit cf cfc cdi trén déu sai, 28, Qua tn bid ign gen gm cd: A B. c. D. E. uaa im vite Qui trinh suo chép vi pia (Qué tinh choydn ma v sa chép. (Qu tinh nh diva gti ma. Qua trnh ain div chayén mt 29. Chon edu SAL A B mS9 ARNm duge ding lim khuén cho su gin din céc acid amin vi nhau theo mit ‘tht te nt din tgo nén protein dc higu (O té bio o6 nhin, ARNm duge ting hop & bdo twong da trén khudn la mt s9i ADN. ‘Chiéu tong hop ARNm xy ra theo chiéu 5° > 3° ARNim lé bin sao cia mt gen cfu tric nim trén ADN, ‘Gen khdi déng la noi tiép nhgn ARN polymerase. 30. Chon ed ding: A B c D. E Qui inh Kt hop acid amin vk ARN thi King cn ng upp ‘ci ani oe in huts da oom bing lh gin od cha ARN vi khudn, acid amin diu tin tham gia ting hop protein la Methionin, (Gini doun ko di chubi polypeptide ham gia ca ce yeu tb ko dF Sw tg lita két peti gion cic acid amin voi nha tong gsi doan kéo el chub polypptd ky anh enzym peptdy ransfrase. 31. Chon eau ding: A B c. D. E (Gen cdu tric cit tf bdo king nhin va tf bdo o6 nbn déu c6 nhimg doan ma ‘héa gp l exon va ning dogn Khéng mf héa goi la inron. Phin ti tién ARNm 6 chu dai ngén hom ARNm tuong img, ‘Ribosom ob 2 vt tip nn: vj tr A va v tri B, Lin két git acid amin vi ARNE I ign tester. Buse 3 (chuyén vi) ela giai dogn kéo dai chub polypeptid xay ra Khng cén ‘ning Luong, 32. Khang sinh ndo sau diy gin cin sy gin aminoacyl - ARNt vio vi tt A cia ‘bosom? 167D. Chloramphenicol E. Erythromycin V1. CHON TAP HOP DUNG: 33. Chon fp hop ding: 1, O18 bio o6 nba, protein dupe ting hep & nha té bao rbi moi duge dus ea d80 ‘wong. 2, Gini dogn kt thie tng hap protein cs tham gia cia cdc yt gi png IF 3, Sau khi duge ting hop, ‘Met hote {Met khOng phai lé acid amin dtu tién cia protein i nb 8b loa 44. Sau hi dage tng hyp protein ry xodn cua to nda ed tc 2, 3,4 5. Chloramphenicol ite ché hoat dng cha enzym peptidy! transferase, 5. ri moos 5 34. Chon tp hop ding ‘MA di truyén lt ma thodi hoa. MALUGG li mot trong 3 ak thie. "ADN trye tigp tham gia sy tng bgp protein ‘Aminoacyl ~ ARNt synthetase va pepidyl transferase déu la nbng enzyme tam gia vio qua trnh sinh tng bgp protein Viti A ea sibosom lino tip nbn acid amin, A123. 5 B34, cha D.25. E145. 35, Cho ctu SA ‘A ARN polymerase hing ARN hay ARN replicase xe the tng bop ARN 8 sng wk ARN ko, 8 Oper dni en DN, eK nn bt genclu wie C. Ludi thuyét trung tm néi vé qué trinh truyén thong tin di truyén tir ADN qua ARN 110i t6i protein. D. Méi chudi polypeptid dirge ma hod boi mot gen cu trie ‘hay cistron. E. Qué trinh bidu hign gen dién ra qua 2 bute: chuyén mii hay sao chép va giai ‘mii hay phién dich. 36. Chon cau SAI: A. Ma két thic la UAA, UAG va UGA. 168D. MA duge doe theo chiéu 3° 5°, E, Mi thodi hod la nhimg ma cing milhod mgt acid amin, 37. Chon efu SAL ‘A: Sw chuydu ud con dupe go I su phién mB, sting hep ARN dya én ‘buon la ADN. = ‘Thin phn cia operon gbm o6: gen tie dng, gen kd ding va mét 6 gen clu trie, Ce mi ing vi met chubi polypeptid thi dupe xép ibn nhau theo thi We ‘twong ting voi thi fr cia cic acid amin ci polypeptid. Transcriptase nguoe xie te sx thg hop ADN b8 sung dva tren kh It pint ARN. , Sw chuyén mbit du th gen didu hod poe 38. Chon edu ding: ‘A. ARNm cé thé 1A bin sao cia mét gen cdu tric hay nhiéu gen cd tric, 'B, Qua trinh két hop acid amin vi ARNt thi khéng cn ning lirgng. C. C6 tht cd 20 ARNt tmg voi 20 acid amin. D. Sian di kin cho thing tn i nye dug yd ty ADN sang ARN, E. Polysom la tép hop nhiéu ribosom gin chit ché v6i nhau. 39, Chon ct SA A. Cie mi ba cia gen cdu tric & ADN duge sao chép thinh efe mi & ARNm trong qua trinh chayéa ma. B. Sw hogt hod acid amin clin ATP va Me™ . O18 bdo nbin s0, acid amin me dt la methionin, D. ARNtcé 2 vai tr: vin chuyén acd amin vi doc mi. E. Ribosom la nha méy ting bgp protein. 40. Chon céu ding: ‘A. Lin kt gita acd amin vi ARNt Ua lin két est. B. C6 60 acid amin- ARNt synthetase tham gia host hod 20 log acid amin. C. Mot ARNt cé thé vin chuyén nhiéu acd amin, D. Nhanb tiép nhiin cba ARNt bao gid cling c6 bj ba CCA 6 du 5’. E, Ribosom ¢6 2 vi tr tiép nhan: vj tri A va vi tr B. 41. Chon cfu SAI: ‘A, O té bio 6 ahi, giai dogn mé du cia sy ting yp protein 6 sx tham gia cia eid nin metonin BB, Enzym xtc té sy ting hop aa-ARNt la amino acyl ARN synthetase. C. Cub d6i mB 6 bp ba déi ma dic higu d6i véi acid amin duge ARN! tong ‘B. Enzym tham gia qua trinh chuyén ma la ARN. ‘Polymerase . Mima ng voi métacid amin gbm 3 nucleotide noe | ing vn chy, | | 169D. Siri bikin cho dng nd ruyén dupe raya ADN sang ADN ciatd bo can, E, Phin tirtitn ARNm cé chiéu dai ngin hon ARNm twong ‘mg. 42, Tinh da dang ca protein dye quy Ain bai: ‘A. Nhomamin eta céc acid ami B. Nhim Reda ee acid amin C. Lita két peptid D. Sé lugng,thanh phn acid amin trong phan ti protein E. Tréttyracid amin trong phn protein 48. Thirty cc phn tha gi vio qu trinh sinh ng hep protein: ‘A. mARN, ARN, ADN, polypeptid B. ADN,mARN, polypepid, (ARN CC. tARN, polypeptid, ADN, mARN D. ADN, ARN, tARN, polypeptid E. ADN, polypeptid, mARN, tARN 44. $6 mi ba chu tich nhiém ma ha cho cde acid amin a An B27 C61 D. 64 E92 45. Sin pm cub ing cba qu rah host hi acid amin A. aARNtsymetase B. ax-AMP-ARNt syabetase C. arADP-ARN syuthease D. ae ARN! E. asARNm 46. Qua trnk pin ma Khong xay ra 5 b9 phn ndo eda té bio A. Té bio chit B Tithe | C. hin f bao D. Lye lap 47. Puromycin te ché sinh téng hgp protein vi: A. Gly kb thie cui sia 1B. Ngdn can sy chuyén ma C. Ngan edn céc tiéu don vj ribosom 30S va $0S két hop trong giai dogn 1nd du. D. Ue eé pin ing chuyén vj E, Ucché phin img do pepidy ransfase nc the 17048, Diu nto sau ddy KHONG DUNG ‘A. Operon i don v hoat ding cia ADN. ‘B. MB thodi héa i nhtng md cing ma ha mot acid amin - Cuba dBi mi 6 bp ba 4b mi de hidu 4b voi acid amin duge ARNE tuong ting vin chuyéa D. Giai dogn ké thi cé su tham gia cia yéu 16 gid phong (RF) . Khi kt the ay tbug yp polypepti, ARNt vin bm chit vo rbosom, 49. Chon cfu ding ‘A. Sy chuyén ms bit ut gen didu ha B. Cle mi wén ARNm ng vi mat chibi polypeptid hi due xf ia nau theo thir tog ig vi th tyne acd amin ea polypepi . Ma kétthie I UAA, AUG, GUA, D. Transcriptase ngupe nc tc sy truydn thing tin aguve protein i ARN. E, Che fu én db ding 50. Chon eéu ding amin khi duge host héa str thinh phn tr gu ning hugng Aid ania Ka ip vo cul pope dang du: ting bop ; C. M@t sb ARNt s& duge didu chink saw khitgo thin 48 phi hop vi hinh ng cian. D. Khoiing 50% sé dupe iu chinh bing céch thay thé mt nh6m chite héa hoc E, Céc edu tin ddu ding => 51. Chon edu SAL: ‘A. Surchuyén ma bit iu tr gen te ding B. Tren phén tir ADN cén c6 gen diéu hoe C. ARNm trgc tiép tham gia qué trinh sinh ting hop protein . Qua trinh spicing ARNm xay ra trong nbn té bio E. Téng hop protein xiy ra 6 ribosom. 52. Chon efu ding ‘A. Ki nghién cfu cfu tric cia protein, phuomg php tinh thé hoe tia X cho ta hin anh dng eia phn protein 'B. Protein sau khi duge ting hop tip tue bin d6i dé tg0 thin cic protein chic ning. CC. Bin don vi nhé eta ribosom gin vao ARNm va tng theo chidu 3° — 5° cia ARNm. D. © 88 bio nha thi, acid amin mé alu la Met, dupe vin chuyén dudi dan methionyl-AMP-ARN. . E. Khéng ¢6 cfu no ding, 53. Clu ndo sau diy KHONG DUNG: ‘A. Viti gin amino acyl-ARNt 6 ribosom lav tl A m54 vu 55, 56. vu 31 B. Sting hop protein xdy ra trong nhin té bio CC. Ban dom vj tm va bln don vi hd cia rbosom Abu tham gi vio du ete stag hop protein, ahung bén don vj nb tham gia trae, ban don Vi ‘em than gia sa D. Vitel hu peptid!-ARNE &ribosom lv P B. Peptidyl transferase la enzym tham gia tgo lin két peptid gitta cdc acid amin. Chon cu ding ‘A Acid ania img véi mf mi du tong sinh ting hop protein @ vi Khwln lb vali, B, Qui inh bu hin gn dfn ra qua bai bude: chuyén vA gi ml. hl on a gi ag hp pin tm iin mb RF. D. Ribosom cd 3 vt tiépnbdo: vi A, vw B va vi tC . ADN polymerase than gia trou gai doqn ke di chi polypeptide. ‘CAU HOINHAN QUA: “rong qu tinh sao chép, aking ma ti ADN dupe chuyén sang ARNm vf ADN urge ding lim khudn cho si ting byp ARNm. Chon tu ding, ’A. Chl vu ding vi v2 khdng wii hich vé 1 B. Cha vé i cing va v2 gi hich v1. ©. VE ding, 62s D, Ver si 2 ding E Ch2vedbu a ‘Acid amin mo dd cho qué tinh tng hop protein & E.coli la formyl Alsnin yl E.coli Tid bio eb ain hon tu ding "A. Chai vé déu ding va vé 2 hn gi thich v6 1 B, Chai vé bu ding va vé 2 gi thich v6 1 ©. VEr ding, vé2 sa D, VE sai, vé2 ding B, Ch2vé ddusai ICAU HOI BOI HOP: ‘Chon déi ma (irén ARN) twong img voi ma tren ARNm ARNm ARNE 1. GCA AAUA 2, GAU B.CGU 3. ccG c.Gac 4. UAU D.CUA m58. Chon enzym tham gia vio mbi qui tinh sau dy: 1. Nhin 461 ADN, A.ARN replicase 2 Nhin 461 ARN B. aa~ ARN{ synthetase 3. Saochép (C.ADN polymerase 4. Gidima D.ARN polymerase ‘Vil. CAU HOLNGAN CAI TIEN: 49, Cho big ning thay 4 ia phn protein saw ki cage tng hop 60. Mi t git dogn kth oi urn sinh tbng hop 6 E cl 173CHUONG 15 LIN QUAN VA DIEU HOA CHUYEN HOA 1. Chit nfo sau dy KHONG duge xem la chit “ngl ba dutmg” AA, Acetyl CoA B, Oxaloacetat . Trigcerid D. Glycerol Pyrat 2. Chu tinh Cori ld chu tri ‘A Lign quan dé sy tgo thinh lactate 6 co vi chuyén lca v8 gen B.Ligu quan dé su tog hop vai gi teghyeerid 6 md CC Lign quan déa sy tng hop vat dag tht ceton 6 gan v8 co D. Lite quan a chuyen hoa Kh lucose tg ng kung © 20 Lian quan a sy thodi hot nto cin acid amin gat 3. Chuyén hod xy ra 6 cf ti thé va bao trong: ‘A. Tia go glucose 'B.B-Oxi hos acid béo C. Téng hop protein D. Tag hop NAD" B. Too thé ceton 4, Vé lién quan chuyén hod: A. Sucinjl-CoA tam gi to globin B Amin hod oxaloacett io alsin e:Ciat aedee i quan vi chu tia uré qua arginostsinat Gon dvdng HDP cing edp NADPHLA" vi ribose SP Con ding HMD cung bp oxaloeciat cho chu tinh aid civic 5, Vé ign quan chuyén hos: ‘A. Chu tinh acid etc I iat dog hod hot cub cing eta ring lucid B AceiyLCoA la sin phim thodi bod chung di vio chubi ho apt bio 4 tao ning lrg . aoe CH hp bo Ta qu tn chy hing cin qua thng enzym, 1D. Protid cin duge chuyén hod thi glucid true khi dupe sir dung dé to ning hugmg E. Chu trinh acid citric sinh ra CO> 6. Véliin quan chuyéa ho ‘A Lactat i chit rung gan ge chayén ho lucia vi pi 143. Ho hip t bio ke mhau tung ing vi tng co ht lucid ii, poi C-ATP dang ich ening omg chung cho chuyén he gud fk ota D. ATP céngubn gb kd ahan dope si dang theo cleh Kase no ei phéng ning omg mie d6 tong ding haw 7. Su thdognhlt chyba ho thé ign &, NGOAT TREY ‘A. Chu tinh Cor B. Chu tinh acid cite CH hp tf bio D.Tich rnin lung E Sir dng ng lung 8. Vélitn quan chayén ho ‘A. Alain bj Kit hin pyravat 6 thé sir dng 8 tg hop elo ng Kg thé tham gi ng hop lipid an hogging gfe 1 ghse th ia tia hci shim kn ih chuyén bo hi cid ain ©. Cécile iid proidkg th thay ny ota od ce D. Glucid, lipid, protid c6 thé bién déi que Isi trvc tiép khéng qua chit chuyén tos tng ga ch E, Cle st phim toll ot chug cin gui pi, pod hg s ng. uve trong ting hop glucid, lipid, protid 9. Ché dp dinh dung phai hop 1, i cht vi ti nhitdinh vi, NGOAT TRU: ‘A. Khng thé thay thé hodn todn lipid vi lipid 1é ngudn nding lupmg chi yéu cia co thé 5B. C6 mts acid bo cn hit co thé kndng tbng hop dye C. C6 mts acid amin cin thit co thé Khong tbng hop dupe 1. Cothé iu nh kibng tg hop dupe vitamin E, Cie yéu tb vi lugmg can tit cho ede phn img sinh ho trong cath 10. Vé mi gn quan gta chuyén ho ip vi picid, roti, chon ch SA ‘A. Aca bo trong tglyeridchuyén thin phosphodoxyaceton 3, Phosphodioxyacton sau dé de chy thinh phosphoglerldehyd C. Phosphoglyceraldehyd bin thin gucose qua tn to dong D. Phosphogtyceraldehyd bién thanh pyruvat rBi than alanin E, Phosphoglyceraldehyd cling c6 thé dupe chuyén hod tiép tue 8 di vio chu trinh acid citic 11. Vé liga quan chuyén hod, chon edu SAL A. Glucid, lipid, prot c6 thé bin di qua lai dupe B, Cé nhiing chit ‘ngl ba during” Nang lugng do chuyén bo glucid, roi, iid khdag mit di dang mide md di tr dang ATP 15, Cé sy lin hop git phan ig thodi bod va ting hop E. Co sy lién hgp gitta cée qué trink chuyén hod 12, Vai td cli chu trnh acid citric trong lién quan chuyén hod: ‘A. Cung ep oxaloaceta rong thn go glucid B. Cung elp pyruvat dé wng hyp acid béo CC. Cung elp oxaloacetat ong tag hop acid aspartic | D. arCetoglutarat duge chuyén amin thinh glutamat dé tham gia chuyés hos protid i , Cung cép succinyl CoA trong ting hop hem ‘Tit edu 13 dén cu 24: Ghép chit chi vj tricia cde qué trinh chuyén hos: ‘A Bio dich Bite (CB ch vai thé D.Nhin E.Ribosom 13,__ Tin io glucose 14,_ Bung pin 15,__Téng hop NAD" 16.__ Con dubng HMP 17.___ Tao thé eeton 18,_ Tong hop acid bé0 19,___B-Oxi od acid bo 20.__ Tyo em 21,___ Chen wré 22,___ Ting hop protein 23.__ Tong hop ADN 24,_ Tong hyp ARN 25. Vi quan he chuyén hod git cic md: 176 ‘A. Cove chie nang glycogen nén cung cép glucose cho mau khi ndug 6 glucose més hip B, Gane chi nny glycogen gp dy tt glycogen ki nbug d glucose mu ca0 . Qu ah oxi tod acid bdo bo ho ch yu xy ra gi m6 mi 3D.Pin kn acet-CoA to tinh i acd bdo di vo chu inh acid cite & gan E Binh dung tiglycerid due ting hop 8 gen va ish sn oe 26, Ngudn ning lung chi yéu eta no a A. Fructose B. Acid béo C. Glycerol D. Glucose E. Mannitol 27.V8 ehuyén hod 8c ‘A. Cie thé ceton va acid bo la ngudn ning tug Kh co nghi B. Glycogen dco chiém 2/3 tng lg glycogen co thé . C. Coa ngubn cung ep glucose quan tong tong diéu hoa duimg huyét 1. ThE cetonduge tgomhiu nh la co __ E Khi co hoat dng, thodi ho glucose theo con duimg yém kh bi bit hot 28. Vi chuyén hod 6 co vi mb ma, chon ctu SAL: ‘A. Lactat to thinh 6 co duge chuyén dén gan dé tin yo glucose B. Corti sr dng acetoacetat hon so vi glucose C. Acid bg dupe vin chuyén trong miu a VEDL M6 ma noixay ra qué tinh ting hyp va phn gid tighycerid E, Acid béo due tng hap chi yu tg md me 29. Chu trinh alanin 14 chu trinh, chon edu SAI: A Tug tn chu inh Cor i alain thay cho lactat B.Alanin dugechuyénvé gan dé to thih glucose .Cé sn phim pki chyén ho gan Is rea D. Duge to thin te pyrwvat trong co C6 vai rd quan rng ki co nghi ng 30. Co ch thay 48 hop a enzym trong did ho chuyéa hod ‘ALi thay 8 ugg ery B.Ditu hos chim . . Khvng bj ak rng bo nn 49 coc ode coenzym D. Tie d chuyéa hod king di E. M@t trong ci co ché nay la did hoa di tp thé 31. Enzym dj lip thé A.Lé enzym c6 rong ti i lip thé hay vi tng tim hot dng 'B, Chit te dung an hung ln sr tiép nin each cua enzyme C. Cor ché dieu hoa la su thay 44i nding 48 coenzym D. Thuge co ché digu hoa cham E-Khie6 shot hod lp th, hog tinh cua eneym gm 732, Vécorché i lp thes ‘A. Chit td dung lim thy di cu tric king gian cin trang tim dj ip th B. Glycogen synthase Ts enzym lp the dm véi chit tc dng Ia glucose 6- phosphat . . Phosphotructokinase bj he ché di Hp thé boi ndng 43 AMP cao ‘1D. Co ché te ché nguye rit phd biéa trong diéu hoa chuyén hoa He thong mulienzjn thong duge dio hoa qua co ch dlp thé duong 33. De dm cinco cht te ch ngugs, NGOAL TRU ‘A. Xiy ra chi pin ig dn dn tg bop B.S phim ci thug ai chit eb cc ipa (CS phim eubi cing ein chi psn ing Ge ché lp Ne wénenzym du tén chub pa ig : 1. Eagyn dug cua choi phn ing ery dp te E. Cite ch nguge cO cu tie hf bge noon tex cit ein enzym mind te che “4, Fructose 6-iphogphat host hod pyruat kinase @ gan. Day 1 co cs ‘A. Diduhod tifa B.Digu hod nguoe CC. itu boca wan D. Dp thé Am Biba oa theo ming 49 co chit 35. Didu ho chuyén hod theo cach An hung sn ng hop protein: "A Trong coc iéu hod im, chit kim hen rye tifp is che ARN-polymesse Operon gbm2 thin phn dan kh ng vt dogs te (C-Gen didu hod dm 6 dogn ADN gida dogn tc ng va gen cutie D.Gandibu boa chi hay vige Ong bop protein E. Protein du hoa gan vi gan cutie dh dn sychuyén nk 36, Bidu hod chuyén hod theo eo hé an hug sinh tng hap enzym, chon céu SAL: 'A-Trong co chi didu hod dm, cht km bm gin v6iP vi gin cin sy cbuyén mb BB. Troug eo ehé iu hod og, chit hoat hod bim vio Pv Khbi ng se chuyen ma : ©. Go chi did ok dm ob 2 loi gi, R gn wi P ving gen ei, RE gin vi cht kt i gin voi P vi dng ge ; Sioa I a co chi di hod dong, chit host hot gn wi ci thm vio P vi ma gen Operon typlophan 6 Ecol ® 5 gen eu ic ng v6 Senzym rong ng hop \eyptophan 37. Didu hod cen hod theo oo ln hung sin bg hp poke: bi 8 4. Sip ia en ia ta gern prin kin ln Rn ng v8mo gen, CCAP la chit kim ham tng hop eéc enzym ting hgp lactose { _. Lac operon gdm 6 gen cfu tri twong img véi 6 enzym thodi hod cia lactose - Khi CAP bim vio vi tr tuong img & ADN va R’ khéng bim vio P th lac ‘operon mé va qué trink chuyén ma xdy ra | Ki R gn i cht Kt yop thin hid toh hp im vo Pv 38. Diéw hoa chuyén hod theo co ché anh hwéng sinh tong hyp protein; A. Khéng anh huong luong enzym Da ao sy ng in ung tim hot dg ca exzym ©. Coed sinh tng hp enzym cng chin ico ch sinh tng yp protein } D. Gen diu hod Iudn nim trong operon tuong img E. Protein iu hong cin st bam vo gen Reda ARN polymerase | 39. Didu hoa chuyén hod theo co ché an hutmg sinh ting hop enzyme, chon céu SAI: A. Ln quan n operon 3. Glin oh ng op ck ag nb on Engng bp hots ech og .Teong th nghiém Monod va Jacob lactose chit ng ebm E. Trong diéu hoa ém loai I, chit két-R’ khong bim P nén gen mé 40. Clu trie eda mgt operon cé dic diém, NGOAI TRU: ‘A.Cé thé chit 1 hogenhidu gen cu tie 'B. MBi lin chuyén mi 8 dupe 1 ARN tuong ig vi I gen cd tic C.Boan kh dng (promoter) li noj gin ARN-polymerase . Bogn th dg (operator la noi gin cht host hod ode i che E_Dogn tie ding o6 vai td dng mo gen edu tic at 191. PCR: CHUONG 16 PHAN UNG DAY CHUYEN POLYMERASE La phan ing nay ra trong co hd sing ‘La | kbd trong qué trinh sinh tong hgp protein L& I phan img ohén ban tinh ty ADN quan tim trong éng aghigm dya vio ct chu Ky nit. a quitinh chuyén ma ditruyén [La qué winh sao chép thong tn di tayén ere poe 2. Phin img PCR duge xay dyng dya trén: “Lage thuyét trang tim cad uy Tin chit ha tan vi th cia protein ‘Tinh cht kh ben boi nit ia enzyme polymerase ‘Nguyéa ie ng quit cia sy pin chi 1 bso lt ADN dug nbn bi Ea rong nin bio 4 phn phi ch 2 bo con. , Tinh chu nit oa phn tr ADN poRP 3. Trong qué trnh ly trich ADN: ‘A Vai td eda proteinase K la lim bin nh protein ming tf bio, ming nh vi protein im ADN 3, Vai tb cia guanidine thyocyanate I thy pi protein . Vai to cia phenol: chloroform a lim big tinh cic thn phn procn khng thong mud wong mu va King ha an sid nucleic “ait ea ethanol nd 6 ca a bay ot ube Vai ei isopropanol a hoa tn acid mle 4.88 gia gn Bi chu phn ig PCR aya 5. Trot 80 Al DOP ng ning chit sau chit no khong cb mt trong PCR mis: ‘A. Taq polymerase B. 4 logrgNTPs C. ADN dich D. Cie dogn mbi xudi va mii nguye E. Nal6: Khodng nhiét dp lim bién tinh ADN trong phan tng PCR Ui: 55°C -60 °C 7°C-7°C ~ ~ 90°C -94%¢ 95°C ~ 100°C. 100 "c— 120% moon 7. Khodng nhitt lim cic dgan mi bit cp sung vio ADN dich 55°C -65°C m= 72°C 90°C -94°C ). 95°C - 100°C 100°C - 120°C Poop 5. Nhigt 4 thich hap cho Taq polymerase kéo dai dgan ADN bi sung véi ADN dich hi A. 55°C~65°C B. 70°C-72°C c D. E. 100°C- 120°C 9. Chon céu ding: ‘A. RT-PCR li phin img khuéch dai ARN tic ADN 3B. Nested PCR li pin img khufch di mst doan ADN dich bing clch st dynp nhieu cfp méi dd higu cing mgt ic trong mgt bng dng nghiém C: Muliplex PCR lt phn mg khudch dai mt dogn ADN lich bd nhiéu phn ling PCR trong cfc bng nghiém khée nhau D. Hemi-nested PCR (PCR bin ty: sir dung 3 8p moi E, Realtime PCR It PCR dinh lug, sir dung cde dgan d (probe) phit hush ‘quang dé phat ign sin phim PCR theo th pan tye, 10. Chon edu ding A. Un dim cia enzyme Tag polymerase a host dng 637°C 3. Tag polymerase dye tach chit ivi kin Therma aquericus C. Tag polymerase dave tich chit ti Ecol! D. Taq polymerase i enzyme khéng hot dng 6 mht dd cao 5: Nie diém cia Taq polymerase Is ngudi lim thi nghiém phi itn ye mo ‘nip tube PCR dé b sung enzyme nly sau mdi gil don bizn 11. Chon cfu ding 2: Gut | shu shiét mbt ADN dich chi duge nhén hin 1 hin sao B Qu# 35 chu kj nhigt mgt ADN dich nn bén duoc thank 2 tan soo C. Neu pt minh a phin img PCR la Crike _D. Nauti pht min ra phin img PCR la Watson E. Phin img PCR duge phat minh vio nim 1953 18112, Phuong php oe tic ngoi idm sin ph khutch dpi ADN eS higu qua nti: ‘A. Thay ging thug xuyén BB. La alcohol noi dt phn img PCR C. Ding PCR mix ci thém dTTP va enzyme UNG D. Ding PCR mis ob tein AUTP vi enzyme UNG E, Ding PCR mix e6 thém dGTP va enzyme UNG 13. Chon céu SAL ‘A, Mii li nitng dognoligonueleotd di 20 ~30 base BB Méi li nhtng doan oligonucleotd dai 200 ~300 base C. Mii ding vai tr quyét dinb tinh de higu eta PCR dé niin bin mt doen [DN die higu no d6 D, Nbigt bit ofp (T,) thing thip hon nhigt 4) ning chéy (Ta) ob mdi hosing 10°C . Nhigtd6 ng chiy eta mi phy thuge vio chidu dai vat 18 G + C 14. Chon cu SAL: Vige chon indi (primer) cin dia theo mt sb nguyén the sau: 'A. Nin chon mBinio trong edu tie o8 thé to ra dang “td cl hari) hi ho vio ue vl dang tm ci lim cho mi bm vio ADN dle 3, Diu cba mdi nin C hope G 4 mdi cd the ket hop che en wi yin CC. King nénehon mdi cS cu trie aha; ATC en TAG. D. Khéng nén chon mdi co cdu trie nhu sau: ... CCC GGG. FE. Nong dtd duge ding tong kong ti 0,1 dén,3 uM cho it nt 30 cu ky ligt 15. Trong ede polymerase sau, enzym ndo Khdng chiu dye uh & cao: ‘A. Tag polymerase B. AmpliTag polymerase . Ti polymerase D, Herculase B. DNA polymerase | 16. Nong dd cho mi logi NTP thuimg dupe ding trong Khoding A. 2-200M 20--200 pM 200 = 2000 4M 020-2 uM 250-500 uM. mgoe 17, Lugng ADN mu thuémg duge sir dung trong khodng Alps B. 10ug C. 100g D. 150 pg E, $00 ue18. Nhiét d& thich hap cho mai bit cip vi soi miu phy thuge vio Ta tnhige dre chay cia msi), Ty dye tinh bing céng thi A. Tw 4(G4+0)+2(A+7) B. Tw=3(G+C)+2(A+T) - ©. Ty=2(G+0)+3(A+T) D. Tan (G+C)+(A+T) E. Ty" 2(G40)+4(A+T) 10.85 foomg ch rong ph ng PCR tharing hina wt gu A.20 B40 c.60 D.80 E10 20, Higu sudt khuéch dai dat durge cao nhat voi kich thurée cia doan ADN trong khoang: A.>3kb B. <1kb ©. >Skb D. <10kb E> 15kb 21. Chon cau SAL: Trong phan iing real-time PCR: A. Sit dung cae doan dé phat hujnh quang phat hién chu kj nguémg Chu ngung lati diém sin phim khuéch di dug phi hin C. Chu ky ngutng ty 1g thuan v6i lugng ADN ban diu D. & the bet due Et qui sao chp ti ting th idm nit dah E. Bit bude phai sit dung chit phat hujnh quang 22. Chon eu ding: ‘A. Hé dng realtine PCR gn: Méy in hig vy vin 'B. H@ thong real-time PCR gém: May ludn nhit, may vi tinh va may quang phd bh quang (C. Trong realtime PCR. qué trith nin ban ADN vi dod pls huh quang 9 1g thudin véi sé lugng dogn ADN tgo thinh dign ra khéng dong thoi D, Ethidium bromide tI lei probe df hu gn hua quang E, SYBR Green it lpi probe di hia ® gin huh quang 23, Chon eiu SA: ‘A. Cle pdm nhugm chén soi bi ADN cho két qua rit de higu 'B. Cie phim nhubm khi chén vio soi di ADN sé phat huni quang menh han i 6 tang thi ty do C. Probe Beacon chi pt hujnh quang khi 6 bit tp de hi wi erin wr dich D. Beacon iI lpi probe dc hifue6 gin hujn quang E, Taqman i! lai probe Ae hidue6 gi hur quang 18324, Chon cau ding: 'A. Eihidiam bromide khi chén vao a9 481 ADN 38 phit sing manh hon Ki trang th tw do gdp 50 in 'B. SYBR Green khi chén vao soi di ADN sé phat séng mann hon khi & wang, thine do gp 500 in (C. Taqman kh cin vio si 461 ADN s8 pht sng manh hon Ki 6 trang thi oy do gap 100 lin D. Beacon kh chén vio si 461 ADN spat sng manh bon khi & tang th np do gip 200 tia . Cée probe gh hujl quang khdng phit sng ki 6 trang thy do, 25. Clign eh ding ‘A. Tin ida hujahquang due hit aki probe Taqman gi vb primey 40 'B. Tin higu buyah quang duge phat ra khi probe Taqman gin vao ADN dich bi DNA ppmerese pn tong git oan nb i sb sng Tron ite Taqman probe cht ph bj aang ge hn li reporter (Gob pi pa quang ng tc bg chit hp hy quencher (Q) (Cu te ea Taxman probe tung yo tee la Beacon poke uence hl nm sa ep ong cu te Tagan probe moo 26, Chon eu SAL ‘A. Quy tinh tg ign realtime PCR boo ghm: Ly wich acid nucleic, tn ign phan dmg PCR, chay dign di dge két qué B. Quy trinh thye hign real-time PCR bao gdm: Ly trich acid nucleic, thy hign phn ing in thong reaime PCR, pn ch va blo cdo Kt qu tn he thong nay . Cc. Trong kj tht real-ime PCR, din lugng nag 4) ADN mu (sume bing cet so sinh Ct vi Ct ia chun (andard 4 id trate ng 49 . Hu qua pin mg realtime PCR khong bao gi dt 100% TE The hot ian enzyme mgt mei vi hat dng gi 6 th ng ti hits phan img PCR. 27, Ke qui ig di sin phim PCR st hly ge vas band) @ Khong ch ky th my nu che 100 sopy ADN trong miu Ag 0 2 2 30 mooe 28. Chn céu ding A. 96 mdu lip Iai cus eting mdt ning 43 ADN vac djnh cho tin higu hun quang © gii dogn cubi(Ké thie) hod tin gidng nau. B. So sinh két qua dign di ten gel san phim sau PCR cla cing 1 ndng d ADN dich ban Adu thay cdc vach yiong bgt nhau vé kich thude chu ky 43, 44, 45,