axnot6 Preryglum Teamont & Management: Medial Care, Surgical Care Pterygium Treatment & Management + Asthor: Jerome P Fisher, MD, FACS: Cie Eltor: Hamgton Roy. St, MD. mere Medical Care Patients win perygia canbe observa uns the lesan exit growth toward tne entero the comoa othe patent exhib symploms of sanfeat redness, Surgical Care Surgery for excision of pany ually performed in an outpatient eating under Tecal or opal anestnela wth sedation, # necessary. ‘A prospective, randomized interventional study by Khia et l assessed $6 patios whe underwent pterygium exasion with MMI application and an arte sat !"10F thse 55 patients. 28 ecoved MMC onthe peiimbal bao er from TS minutes whoreae 7 lhe patient ecaieg MIC under Ie conjunctiva. Endothelial studies reveals loss of 3.4 of cle nthe bare sclera group ampare th 4.8% in he spconjetal grap at months, No competion ‘we observed in either grup, poweves, the study was all ‘A prospective, nonrandomized study by Bahar etal examined the ak af endothe Call oss n 43 sject ellowing pleygur surgery with MVC and conuncval sutograt. The study includes a cat! grup whe hes 2 primary pleygium fxcision without MMC. Although the rumba of patents in each group was sll ‘onthe, comparad ‘wh ne loss inthe conta group. Ths suggests that MM can Affect tho endo col counts in palors wnépoing plongium exison, Despite the relay smal sample sizes, both studies eprtd statistically ‘month ater surgery. The authors note that placement of MMC. the limbus can bo a rs aco for seleral malls. Thus the autos advise placomont of MING ony pleylum surgical ochngues ivalng xtansve exciion af evening conjunctiva nd uncotyng Tone fas In tho vty of ho plenum, combined with alge, limbal-sparingsutogat harvested from tne super cnjntval surface Hit ineludng 80% primary stanygia and 194 rcuren lena. The author had allow: Up oflergor than t yearn 86% of ths pation, wih a mean follow of 618. days. Ths author teprted only ane ocureace among thaws 1000 patients, Signeary lower han hasbeen prewculy pated fr bath pmary and scondary peyeum surgeries This tectnique a not raqure the use of antimetabolites and lt pared Imbel tem Calls ath sito of corjunctvalautograt harvesting. In aden toa reduction Sepocid osurences, Hist aka reported a ower fle ot posioporalive omplations wth fewer than expected postoperative granulomas and fier han ‘epected conincval incision oft, Postopeatvaly the oye is generally patched ovemight, ands treted ‘bsequenly wi toprel antboes and ant-iniamimatry crops andlor ointments. Moseaton Contributor information and Disclosures ‘Jorome P Fisher, MO, FACS Voluntoor Associate Professor. Department of Ophthalmology, Bascom Palmer Jerome P Fisher, MD, FACS i @ member of the following meseal sets: Amorcan Academy of ‘Opninaimaiogy, American Cologe of Susgeons, Amencan Meda Resoeston, Farida Maen Associaton Disdonue: Nothing to dete Coauthors) of Opthalmelogy. Bascom Paar Eye Insite item 8 Trater, MD is a member ofthe fling medical societies: American Academy of Ophhalmeteay, ‘Amarcan Sot of Cataract and Retacive Suoy ip llemexicine medscape comartile 192527-treatment Drugs, Diseases 48axnot6 Preryglun Treamont & Management: Medical Care, Surgical Care Disdosur: Recoved cansuting fee trom Argan fr eonsuting: Received constng fe rom Alea fr ‘onan; Reeve corauting fee from Gaustn & Lomb for canauting: Recavd caneling fe from Abbot Modis! Opies for consulting, Rnived costing fe Tram CXLUSA Torrone: Roceved consiting fe frm Uns fr none, ‘Specialty Ett Boars Francisco Talavera, PharmD, PhO Adjunct Assistant Profesor, Unvriy of Nebraska Medical Centr Callege of PhamacyEtorn-Ch, Medscape Drug Reference Diss: Rocsved salary tram Medscape for employment. fr Medscape ‘Christopher J Rapuano, MD Professor. Department of Ophthalmology, eferson Medial Collegeof Thomas. ‘hereon Uriveraty Decor of the Gamea Servon,Co-Oredar of Reactive Surgery Department, Wila Eye Hosea ‘Christopher Rapuane, MO i 2 member of he following medial sass: Amercan Academy of ‘Oprinalmalogy, Amorian Ophthalmological Secity, Amoran Sosy of Catarec and Reactive Sugary. {Gorlacl Leva Associaton cf Opthalmologits,Inlematonal Socly of Relracive Surgery, Comea Soul, Eye Banke Aesocation of Amara Dados: Sene(s) as draco, offen, prey, employee, ads, constant o tase fo. Come Sosy Allergan, 2auren & Lomb, io-Tzeue, She, TearScenco,TearLabcor~Sere(d) a a speaker ora member of & ‘speakers bureau for Alergan, Bausch & Lomb, Bio-Tsao, ToarSconcn, Chie Ector Hampton Roy, Sr, MD Associate Ciba! Protessr, Deparment of Ophthatmology, Unversity af Aransas for Medial Sconces, Hampton Roy St, MD is @ momber ofthe flowing mesial sade: Amican Academy af Opthalmology, [Amarcan Calg of Surgeons, PansAmeran Asseiaton of Oprinalmelogy Disdosur: Noting o dscose ‘Adtionl Contos Fernando H Muril-Lopez, MD Senior Surgeon, nia Prvada de Otakmologia CEMES -Femando H Musi-Lope2, MD is @ member ofthe folowing medical sacle: American Acadamy ot ‘Opninalmolony Disdosur: Noting to dscose References 1. Coroneo MT, Di Gielame N, Wakefield ©. The pathogeness of pani. Cur Opin Ophiaimol 1989 Aug, ‘014}2828. (Medline, lit R The seilogy of ptanglum. Trans Qpnhsimol Soe NZ. 1964, 13:22. 4. Saw SM, Tan D. Pteygium: pevaence, demography and actor. Ophelnic Fpidemia. 1999 Sep. 6G} 21028. Medine} ‘etal TU, English OR, Sun exposure and plenum ofthe ey: doseresponse cane. Am J COphiamei. 1989 Sep. 128(3;280-7. [Modine Blum HF. 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Role of conjunctival flammation in sual ‘uteome after amrictic membrane Fansplatation with or wiht es glu for plenum. Comea, 2008 don. 271)585.[Mestine}, 13. Oguz H. Amniotic mame gating wor canjuncivalavtograting in pergiam surgery. Cin Expaiment Ophinaiml, 2008 Aug, 854):447-8:Medine 14. Uy HS, Royes Mt, Flores JD, Lim-Bon-SiongR. Comparison of fbn gue and sures or aaching ‘conjunctival auograts ater plenum exisen. Optthamology. 2005 Ape 12(4} 887-71 (Meda). 15. Khana A, Nazar, Nkdl Ms al. Postoperative conuncvaliflammntion aftr pterygium surgery vith amniotic membrane Wansplartation versus corunaal autora. Am J Optihalmol. 2071 Now 15265) 7358. [Meuling). 18 Kamel S. The Plenum ts etiology and Uoslment. Ary J Oph. 1954, 38:682. ip llemexicine medscape comartile 192527-treatmentaxnot6 Preryglun Treamont & Management: Medical Care, Surgical Care 1, Khon A, lad A, Kis MY, Nazar R, Hashorian H, Behrouz MU. Eff of mitomycin © on oxmeal ‘endota' el eaunts in pleygium surgry role af apteaton leaion, Arm .J Opal, 2011 Nat “51(3, 488-93. (Medlng. 18 Bahar, Kaisrman | Lange AP, Slomoue A, Loving E, Sansanayudh W, a. The fect of items {Con comeal endehaism in pterygium surgery. Am J Ophtnaimal. 2008 Ma. 147(2}447-482.0 Meat} 18, Hirst LW, Prospective study of primary ptongum sugey using pargiam extondod romoval allowed by sHlended conuneial taplaniaton, Qphhaimology. 2008 Od. *¥5(0) 1883-72 (Modlin. 20. Hirt LW. Recurenes and compilations afte ,000 surgeries uking eral extended removal lowed by extended conunctival tanapant. Opninlmlegy, 2012 Now "0("}2205 10, [Mecls] Singh G, Wison MR, Foster CS. Lang-erm otlowp study of mitomycin eye dops as sduntve ‘woatment of plnygia and its comparson with conjuncival autograft anelantaton. Gomes, 1990 Oct 914;331-4 (Modine 22. 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