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Gastro-D Complex (Mastic -DGL - Bismuth Complex)

90 Veggiecaps per bottle.

Suggested retail price: $39.95 both internal and external maladies. Bentonite can be used
Gastro-D Complex is comprised of seven externally as a clay poultice, mud pack or in the bath and, in
synergistic ingredients, including Mastic skin care recipes. Internally it can be added to water, dietary
Gum, which may help to protect the gastric supplements or glazed upon food to help those with sensitive
mucosa; Safflower Tops may help to provide palates.
additional support against H. Pylori infestation, Bentonite clay is sedimentary clay composed of weathered
especially for blood group nonsecretors; and aged volcanic ash. The largest and most active deposits
Bentonite Clay assists in attracting and soaking in the US come from Wyoming and Montana. Bentonite is
up environmental toxins; the inner bark rind of usually quarry mined from deposits that can range anywhere
Slippery Elm protects the GI tract from excess from 100 feet to several thousand feet. This depends on the
acidity; and Bismuth helps protect the lining of the stomach from health and vitality of the land it is processed from and how
stomach acid. far a producer will go to find the right clay with the proper
characteristics and consistency.
Product History From here it is mined from the earth and brought out into
Gastro-D Complex was originally NAP product Gastroguard, the sun to remove excess water and moisture and, to make
which was introduced in 2005 for use in the DAdamo Clinic. It it easier to work with. After the initial drying begins the
was renamed in 2006 for trademark purposes. It was reformulated final transformation. It gets processed (ground) with huge
in 2008 to include deglycyrrhizinated licorice (DGL). hydraulic crushers and it then goes through the final process
of micronization, or fine granulating. This is usually done
Description/Background with the assistance of sophisticated and expensive granulators.
Gastro-D Complex comprises seven synergistic ingredients. Upon completion of this final process it gets inspected by a
Mastic Gum (from Pistacia lentiscus) quality control team and is sent off for consumer use.
The applicable part of mastic is the resin. Mastic tree contains resins Bentonite is very unusual in the fact that once it becomes
including the triterpenes mastic acid, isomastic acid, oleanlic acid, hydrated, the electrical and molecular components of the clay
and tirucallol. It also contains a volatile oil containing alpha-pinene rapidly change and produce an electrical charge. Its highest
as a constituent. The volatile oil and the resin are both thought to power lies in the ability to absorb toxins, impurities, heavy
have astringent and aromatic effects (1). For prevention of gastric metals and other internal contaminants. Bentonite clays
and duodenal ulcers, some researchers think mastic might have structure assists it in attracting and soaking up poisons on its
antisecretory and possibly cytoprotective effects. Animal models exterior wall and then slowly drawing them into the interior
show that it seems to help protect the gastric mucosa during center of the clay where it is held in a sort of repository.
aspirin, phenylbutazone, or reserpine therapy (2). This effect has Bentonite is a swelling clay. When it becomes mixed with
not yet been found in humans. There is some in vitro evidence that water it rapidly swells open like a highly porous sponge. From
mastic extract has antimicrobial and antifungal activity (3). There here the toxins are drawn into the sponge through electrical
is also preliminary evidence that mastic might have hypotensive attraction and once there, they are bound.
and antioxidant effects (4). Licorice
Safflower (Carthamus tinctorios) Tops Licorice has a long and highly varied record of uses. It was
Five interesting abstracts from the National Library of and remains one of the most important herbs in Traditional
Medicines PubMed, when taken in total, present intriguing Chinese Medicine. Among its most consistent and important
information on the components of safflower tops and the uses are as a demulcent (soothing, coating agent) in the
effects of these components. Safflower tops also provide one digestive and urinary tracts, to help with coughs, to soothe
of the very few natural sources of free Lewis A type antigen sore throats, and as a flavoring. It has also been used in
for anti-adhesive effects against H. pylori. Traditional Chinese Medicine to treat conditions ranging
from diabetes to tuberculosis.
Bentonite Clay
There are two types of licorice, standard licorice and
Bentonite, also referred to as Montmorillonite, is one of deglycyrrhizinated licorice (DGL). Each type is suitable
the most effective and powerful healing clays used to treat for different conditions.
DGL is prepared without the glycyrrhizin in order to Actions and Indications
circumvent potential safety problems, and is used for Gastric distress, dyspepsia
conditions of the digestive tract, such as ulcers.
Mastic gum helps support the prevention and healing of
Slippery Elm (Ulmus fulva) bark gastric and duodenal ulcers
The applicable part of slippery elm is the inner bark rind. The lentiscus resin in mastic gum has been shown to
The mucilages are considered the principal constituent. They induce blebbing, morphological abnormalities and cellular
are responsible for slippery elms demulcent and emollient fragmentation in H. pylori cells.
effects (5,1). Used internally, slippery elm preparations cause Safflower tops help provide additional support for
reflex stimulation of nerve endings in the GI tract, leading to nonsecretors (particularly O blood type nonsecretors)
mucous secretion (6). This induced mucous may protect the against H. pylori infestation, to which they are typically
GI tract against ulcers, excess acidity, etc. Tannin constituents more sensitive than are secretors.
have astringent properties (5). Oleoresins of some species are
responsible for contact dermatitis (6). Bentonite clays structure assists it in attracting and
soaking up poisons on its exterior wall and then slowly
Bismuth (as Bismuth Citrate) drawing them into the interior center of the clay where it
This is a combination of bismuth, a heavy reddish-white is held in a sort of repository. When used internally, the
crystalline metallic element and citric acid. RxMed poisons are then excreted with the clay.
Pharmaceutical Information PYLORID states that in vitro, Slippery elm preparations cause reflex stimulation of
bismuth-containing compounds have bactericidal activity nerve endings in the GI tract, leading to mucous secretion
against the microorganism H. pylori. In vivo, growth is (7). This induced mucous may protect the GI tract against
inhibited and the bactericidal effects of antibiotics (e.g., ulcers and excess acidity.
clarithromycin) greatly enhanced. Bismuth acts at the site In vitro, bismuth-containing compounds have bactericidal
of the ulcer by coating the ulcer and protecting it from the activity against the microorganism H. pylori. In vivo,
stomach acid. growth is inhibited and the bactericidal effects of antibiotics
Cranesbill (Geranium maculatum) Root (e.g., clarithromycin) greatly enhanced. Bismuth acts at
the site of the ulcer by coating the ulcer and protecting it
Cranesbill is an effective astringent used in diarrhea, dysentery from the stomach acid.
and hemorrhoids. When bleeding accompanies duodenal
or gastric ulceration, this remedy is used in combination Cranesbill has traditionally been used in combination
with other relevant herbs. Where blood is lost in the feces, with other relevant herbs, when bleeding accompanies
this herb will help, though careful diagnosis is vital. It may duodenal or gastric ulceration.
be used where excessive blood loss during menstruation Bladderwrack contains the sugar fucose, which acts as
(menorrhagia) or a uterine hemorrhage (metrorrhagia) occur. a decoy mechanism for H. pylori. The polysaccharide
As a douche it can be used in leucorrhoea. fucoidin in bladderwrack also serves to inhibit the growth
of many unfriendly viruses and bacteria including H.
Bladderwrack (Fucus vesiculosis) Whole Plant
The applicable part of bladderwrack is the entire plant.
Bladderwrack is a brown alga (seaweed). Synergistic Products
Bladderwrack contains high concentrations of iodine, which Fucus Plus (anti-adhesion therapy)
is present in varying amounts. Bladderwrack is also a source Polyflora (for additional support during bacterial
of nutrients such as fiber, minerals such as iron, and vitamin overgrowth)
B12 (7).
Preliminary clinical research suggests bladderwrack might Dosage
extend the menstrual cycle and have anti-estrogenic effects Typical dose is 1-2 capsules twice daily for one-two months or
in premenopausal women. It may also increase progesterone on the advice of a physician. The bismuth in the formula will
levels (8). Preliminary research suggests that extracts of often tinge the stool a grey-green color and the patient should
bladderwrack also might have antibacterial, anti-HIV, and be advised of this possibility.
antioxidant activity (9,10,11).
Fucoidan, a sulfated polysaccharide derivative of
bladderwrack, seems to be active against a variety of viruses
including the herpes virus, HIV, and cytomegalovirus (12).
Fucoidan also seems to stimulate the activity of transforming
growth actor (TGF)-beta to increase fibroblast proliferation,
which suggests it might be useful for treatment of wound
healing (13). Preliminary research also suggests that fucoidan
also has anticoagulant, fibrinolytic, and antiplatelet adhesion
effects (14). Other preliminary research suggests that it
might have antiangiogenic and antitumor activity (15).
Preliminary clinical research suggests topical administration
of bladderwrack extract might reduce skin thickness and
other signs of aging (16).
See Also
15. Koyanagi S, Tanigawa N, Nakagawa H, et al. Oversulfation of fucoidan
Adhesins enhances its anti-angiogenic and antitumor activities. Biochem Pharmacol
Diet, Helicobacter pylori, and p53 mutations in gastric cancer. 2003;65:173-9.
A molecular epidemiology study in Italy 16. Fujimura T, Tsukahara K, Moriwaki S, et al. Treatment of human skin with an
extract of Fucus vesiculosus changes its thickness and mechanical properties.
FUT3 J Cosmet Sci 2002;53:1-9.
Fucus vesiculosis (Bladderwrack) 17. Whorwood CB, Shepard MC, Stewart PM. Licorice inhibits
11-hydroxysteroid dehydrogenase messenger ribonucleic acid levels and
Genetic polymorphism of interleukin-8 (IL-8) is associated potentiates glucocorticoid hormone action. Endocrinology 1993;132:2287
with Helicobacter pylori-induced duodenal ulcer 92.
18. Soma R, Ikeda M, Morise T, et al. Effect of glycyrrhizin on cortisol
Helicobacter pylori infection, ABO and secretor blood groups metabolism in humans. Endocrin Regulations 1994;28:314.
Interleukin-8 (IL-8) 19. Beil W, Birkholz C, Sewing KF. Effects of flavonoids on parietal cell acid
secretion, gastric mucosal prostaglandin production and Helicobacter pylori
Lewis Blood Group growth. Arzneim Forsch 1995;45:697700.
Lewis antigens 20. Morgan AG, McAdam WAF, Pacsoo C, Darnborough A. Comparison
between cimetidine and Caved-S in the treatment of gastric ulceration, and
Secretor Status subsequent maintenance therapy. Gut 1982;23:54551.
T Helper Lymphocyte 21. Kassir ZA. Endoscopic controlled trial of four drug regimens in the treatment
of chronic duodenal ulceration. Irish Med J 1985;78:1536.
Tumor Necrosis Factor alpha (TNFa)
22. Bardhan KD, Cumberland DC, Dixon RA, Holdsworth CD. Clinical trial of
p53 deglycyrrhizinised liquorice in gastric ulcer. Gut 1978;19:77982.
23. Das SK, Das V, Gulati AD, Singh VP. Deglycyrrhizinated licorice in aphthous
References ulcers. J Assoc Physicians India 1989;37:647.
1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed.
Montvale, NJ: Medical Economics Company, Inc., 1998. 24. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing,
1995, 22839.
2. Al-Said MS, Ageel AM, Parmar NS, Tariq M. Evaluation of mastic, a crude
drug obtained from Pistacia lentiscus for gastric and duodenal anti-ulcer 25. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
activity. J Ethnopharmacol 1986;15:271-8. Commission E Monographs: Therapeutic Guide to Herbal Medicines.
Boston, MA: Integrative Medicine Communications, 1998, 1612.
3. Iauk L, Ragusa S, Rapisarda A, et al. In vitro antimicrobial activity of Pistacia
lentiscus L. extracts: preliminary report. J Chemother 1996;8(3):207-9. 26. Armanini D, Bonanni G, Palermo M. Reduction of serum testosterone in
men by licorice. New Engl J Med 1999;341:1158 [letter].
4. The Review of Natural Products by Facts and Comparisons. St. Louis, MO:
Wolters Kluwer Co., 1999. 27. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
Commission E Monographs: Therapeutic Guide to Herbal Medicines.
5. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Boston, MA: Integrative Medicine Communications, 1998, 1612..
Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO:
Wolters Kluwer Co., 1999.
Model: NP042
7. Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine
algae (Seaweed) from the St. Lawrence River and likely to be consumed by
* Manufactured by: Genoma Nutritionals
humans. Environ Res 1999;80:S175-S182.
8. Skibola CF. The effect of Fucus vesiculosus, an edible brown seaweed, upon
menstrual cycle length and hormonal status in three pre-menopausal women:
a case report. BMC Complement Altern Med 2004;4:10.
9. Criado MT, Ferreiros CM. Toxicity of an algal mucopolysaccharide
for Escherichia coli and Neisseria meningitidis strains. Rev Esp Fisiol
10. Beress A, Wassermann O, Tahhan S, et al. A new procedure for the isolation
of anti-HIV compounds (polysaccharides and polyphenols) from the marine
alga Fucus vesiculosus. J Nat Prod 1993;56:478-88.
11. Ruperez P, Ahrazem O, Leal JA. Potential antioxidant capacity of sulfated
polysaccharides from the edible marine brown seaweed Fucus vesiculosus. J
Agric Food Chem 2002;50:840-5.
12. Baba M, Snoeck R, Pauwels R, de Clercq E. Sulfated polysaccharides are
potent and selective inhibitors of various enveloped viruses, including
herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human
immunodeficiency virus. Antimicrob Agents Chemother 1988;32:1742-5.
13. OLeary R, Rerek M, Wood EJ. Fucoidan modulates the effect of
transforming growth factor (TGF)-beta1 on fibroblast proliferation and
wound repopulation in in vitro models of dermal wound repair. Biol Pharm
Bull 2004;27:266-70.
14. Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions
from Fucus vesiculosus induce platelet activation in vitro. Thromb Res

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