Optimera Product Guide

PLEASE READ BEFORE USING

Introduction
OptimeraTM is a unique complex blend of patented biobotanical extracts combined and developed to help reduce
the signs of aging. Enhanced with sophisticated skin nutrients and rich in Vitamins A, B, C, and D, plant triterpenoids,
flavonoids and amino acids, this science-based skincare works on multiple signs of aging.
The patent-pending SAL-14 extract brings together a combination of unique and exclusive plant botanicals utilizing
the science of bio-actives for skincare. The beginning stage is with the selection process of the plants themselves, where
natural greenhouses are established to control the separation and selection of the plant seeds used in the development
of the ingredients. This important step in the process guarantees the standardization of controlled conditions to set
forth the growing of the plants. The plants are grown in a supervised garden setting within chemical-free farms; this
environment dramatically reduces residue from pesticides, unnecessary chemicals, and the use of synthetic fertilizers.
These delicately grown plants are carefully protected to assure they provide enriched purity.
Next, these botanicals are put together to complement the synergy within the function of the plant. A patented process is
utilized to ensure that only the highest-quality portions of the plants are extracted. To assure a clean and pure extraction
is available, no chemical solvents are used in the process, eliminating the need for high operating temperatures and the
possibility of degrading the ingredients.
Teaming with research laboratories and leading universities, Nerium International was able to put together an advanced
and exclusive complex blend of botanicals from various parts of the world. The mission was to assemble and ensure
only the finest ingredients would be in the finished product, while at the same time adhering to the most sustainable
method of production.
One of the major steps in the process was in the production of the oils. To support community growth, the SAL-14
extract contains oils produced on farms that benefit local families.
Manufacturing of the finished product is carried out in one of the most advanced facilities in the country. Adhering to
strict regulatory requirements, the facility takes extra precautions by utilizing state-of-the-art manufacturing equipment
and testing labs. In addition, inspections and strict quality controls are implemented to ensure the product is carefully
checked for safety at every stage of the process.

Testing
Our Research & Development team is always interested in the testing and science behind our products. So, to ensure
the best results, clinical tests were conducted at every stage of the process from concept to completion of the Optimera
product line. Three separate clinical tests were conducted on the SAL-14 patent-pending bio-active botanical extract.
And a fourth double-blind, 36-subject study was conducted on the finished product. Independent focus groups were
also engaged to help with visual and performance studies.
A wide range of testing was conducted including in vitro (laboratory), in vivo (people), and clinical instrumental testing
(both laboratory and people). All tests were performed in professional clinical settings, and all test results were audited
to ensure accuracy.
Clinical trials showed that use of Optimera led to significant improvements in the appearance of skin dryness after
initial product application. And, after four weeks of use, improvements were noted in the appearance of skin radiance/
luminosity, texture/smoothness, elasticity, and firmness.
Image analysis revealed significant improvements in the appearance of the skins radiance and the appearance of
discolorations after four weeks of use. There was also significant improvement in reduction in the appearance of crows
feet, fine lines, and wrinkles after four weeks of use.

Usage
Both the Optimera Day Cream and Night Cream are built around exclusive bio-active plants in a concentrated complex.
This exclusive SAL-14 concentrate is power-packed with age-defying ingredients designed to add revitalizing properties
to the skin.
Optimera Night Cream:
Use each night. Start by cleansing the face thoroughly. Once cleansed, apply four to five pumps of Optimera Night
Cream on a damp face. The product sets like a mask, so it is normal for it to feel somewhat tight.
Optimera Day Cream:
Use this fragrance-free day cream each morning. To begin, rinse the face; then apply four to five pumps to the face and
neck area. For women: make-up can be applied immediately after. For men: apply after shaving or cleansing of the face.
Optimera products were developed without parabens, sulfates, phthalates, synthetic colors, propylene glycol, mineral
oils, or synthetic fragrances. They are also gluten free and cruelty free. These products are noncomedogenic and ideal
for all skin types.
All-natural ingredients and preservative compounds were chosen based on the synergy exhibited by multiple plant
extracts, adding to the integrity and performance of the product.

Reactions
We take pride in choosing only the finest ingredients in developing our products. However, sometimes the adjustment
to new products takes time and surface irritation may occur during this period. As with any new regimen, care should
be given when you begin use. Should any minor irritation such as redness, itching, or breakouts occur or persist,
discontinue using the product and seek medical advice.
Our individual ingredients are chosen with care and undergo extensive safety testing and analysis to meet the highest
quality standards. Should you experience any adverse reaction or sensitivity to the product, we suggest the following
guidelines:

Skin Sensitivity
Optimera Skin Care products are designed to work with all skin types, but it is impossible to identify every potential
reaction. You may be aware of your skins sensitivity to certain ingredients, plants, or nutrients, so please read the
label carefully to ensure the ingredients contained in Optimera Day and Night Creams are not among those to which
you are sensitive.

Multiple Products
If you are currently taking or using any medication or cosmetics in conjunction with Optimera Day and Night
Creams, they may be increasing your skins sensitivity or reaction with the ingredients present in the product. You
may want to test a small area first.

Skin Condition
The skin is the largest organ of your body, and keeping it healthy is our top priority. Assessing your skin to determine
its condition is an important first step in preparing to begin your new regimen. Should you experience extremely dry
skin, irritation, or inflammation, it is important to seek medical attention before proceeding. Skin that is prone to
acne, eczema, psoriasis, rosacea, or any related skin condition may require professional attention.

New Product Phase-In

Sometimes, using a new product or a new mix of products can cause a temporary reaction. Its important to
remember that your skin must have time to become accustomed to a product in order to determine how it will
interact long-term. If you experience minor irritation, we suggest giving yourself time to adjust to the new product.
We recommend allowing at least two to three weeks as an adjustment and purging period. However, if irritation is
intense, we recommend that you discontinue use of product immediately and seek the advice of a medical
professional.

During the product phase-in period, it is important to pay close attention to your skins behavior. Should a reaction occur,
such as a breakout, redness, or itching, it is important to determine the cause. It is not always the new product; it could
be how the new product is interacting with other products youre using. However, we take your safety and health very
seriously. Should any irritation persist over an extended period of time, we recommend you seek the advice of a medical
professional.

Everyones Skin Responds a Little Differently

Your skin is an amazing, living organ that constantly works to adjust to all types of circumstances in life, including irritants
such as harsh weather, oil, or dust. Even new skincare products and changes in the environment can affect your skin.
For every cosmetic product introduced to the market, there may be a subset of the population that experiences minor
irritation, such as: redness, itching, or breakouts. These may be due to an individual allergy or reaction to one or more
of the product ingredients, or the simple fact the skin is adjusting to a change, or the interaction of products. This may
be a temporary issue that will resolve itself once your skin acclimates to the product. However, if the irritation persists,
discontinue use of any new product and seek medical advice.
The individual ingredients found in Optimera have undergone extensive safety testing and analysis, under a variety of
conditions, to ensure they meet every quality and safety standard. These premium ingredients are carefully blended into
this product at optimum levels to facilitate (when used as directed) the desired effect, while at the same time working at
nourishing and rejuvenating your skin.

Product Ingredients
OPTIMERA DAY CREAM: Aloe Barbadensis Leaf Juice, Glycerin, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride,
Plumeria Auctifolia Flower Extract, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Jojoba Esters, Tetrahexyldecyl
Ascorbate, Sodium Hyaluronate, Sorbitol, Bisabolol, Leuconostoc/Radish Root Ferment Filtrate, Lonicera Caprifolium
(Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Populus Tremuloides Bark Extract,
Gluconolactone, Avena Sativa (Oat) Kernel Extract, Camellia Sinensis (Green Tea)Leaf Extract, Santalum Album
(Sandalwood) Extract, Phellodendron Amurense (Bark) Extract, Hordeum Distichon (Barley) Extract, Tetrapeptide-30,
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Butyroyl
Pentapeptide-24, Hydrogenated Lecithin, Bidens Pilosa Extract, Mauritia Flexuosa Fruit Oil, Acrylates/C10-30 Alkyl
Acrylate Crosspolymer, Allantoin, Centella Asiatica Leaf Cell Extract, Cetearyl Glucoside, Citric Acid, Dipotassium
Glcryrrhizinate, Disodium EDTA, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum
Usitatissimum (Linseed) Seed Oil, Phenoxyethanol, Sodium Hydroxide, Squalane, Tocopherol Acetate, Ubiquinone,
Xanthan Gum.
OPTIMERA NIGHT CREAM: Aloe Barbadensis Leaf Juice, Natural Albumen, Glyceryl Stearate, Oryza Sativa (Rice)
Bran Oil, C14-22 Alcohols, C12-20 Glucoside, CetearylAlcohol, Cetearyl Glucoside, Ricinus Communis(Castor) Seed
Oil, Octyldodecyl Olivate, Olus Oil, Glycerin, Chondrus Crispus Powder, SodiumIsostearoyl Lactylate, Polysorbate 20,
Bidens PilosaExtract, Mauritia Flexuosa Fruit Oil, Caprylic/Capric Triglyceride, Caprylyl Glycol, Centella AsiaticaLeaf
Cell Extract, Cetyl Alcohol, Cucumis Sativus (Cucumber) Fruit Extract, Elaeis Guineensis (Palm) Oil, Glyceryl Caprylate,
Gossypium Herbaceum (Cotton) Seed Oil, Hydrolyzed Quinoa, Linum Usitatissimum (Linseed) Seed Oil, Phenylpropanol,
Sodium PCA, Stearic Acid, Tocopherol.
Thank you for your interest in Optimera Night and Day Creams. If you have any product questions or concerns,
please contact us at support@nerium.com or 888-304-6046.

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