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which may guide surgeons in cases where multiple surgical options are feasible. Future studies, such as randomized clinical
trials, are necessary to ascertain whether novel surgical strategies
have risk/benet proles that ultimately supersede those of
traditional approaches, and whether enough cases are encountered by the average surgeon to justify their adoption.
Key Words: thoracic disk herniation, decision analysis, qualityof-life, HRQoL, thoracic discectomy
(Clin Spine Surg 2016;00:000000)
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Nayak et al
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FIGURE 1. Decision tree, outlining possible outcomes following surgery for thoracic disk herniation. The probability of
complications varies with operative approach, as do the
overall effects of complications on quality of life.
RESULTS
Our online search of treatment reports yielded 880
abstracts, of which 707 were discarded as unsuitable because of language and topics such as diagnosis or thoracic
disks in animals. This left 173 articles, which we downloaded and reviewed. Figure 2 illustrates the assessment
of the literature that resulted in 39 articles (several of
which report >1 approach), totaling 1319 cases, used to
obtain data listed in Table 1. Multiple operative approaches are included in the Posterior and Lateral
categories. If 1 particular approach was predominant in a
given report, it is listed in the Notes column. We
omitted any article reporting multiple approaches but not
separating outcomes by approach. As none of the series,
including those comparing multiple approaches, involve
randomized trials, they can all be considered level III
evidence.60 For measures of preference-based quality of
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Nayak et al
Year
Study Type
Approach
Technique
# Cases
2002
2011
2014
2014
2010
2000
2011
2010
2002
2008
2010
1994
1996
2001
1991
1991
1991
1997
2006
2014
2011
2011
1997
1993
1999
2006
2012
2013
2013
2014
2005
2013
2005
2012
2012
1993
1993
1993
1993
1992
2013
1992
2012
2012
2012
2014
Pro
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Pro
Ret
Pro
Ret
Ret
Pro
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Pro
Pro
Pro
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Ret
Pro
Pro
Ret
Anterior
Posterior
Posterior
Anterior
Anterior
Posterior
Posterior
Posterior
Lateral
Posterior
Posterior
Anterior
Lateral
Lateral
Posterior
Posterior
Anterior
Lateral
Anterior
Anterior
Lateral
Anterior
Anterior
Posterior
Posterior
Lateral
Lateral
Lateral
Posterior
Posterior
Anterior
Posterior
Anterior
Anterior
Posterior
Posterior
Posterior
Lateral
Lateral
Lateral
Posterior
Anterior
Anterior
Anterior
Anterior
Posterior
Thoracoscopy
Posterior transfacet
Posterior transpedicular
Mini-open thoracotomy
Thoracotomy
Transpedicular
Various (mostly transpedicular/transfacet)
Transfacet
Lateral paravertebral retropleural
Transpedicular
Transforaminal endoscopic
Thoracotomy
Lateral extracavitary
Transcostovertebral junction
Transpedicular, transfacet
Costotransversectomy
Thoracotomy
Anterolateral retropleural
Thoracoscopy
Thoracoscopy
Lateral extracavitary
Thoracotomy
Thoracotomy
Transpedicular
Transpedicular
Lateral extracavitary
Lateral retropleural
25 transpleural, 8 retropleural
Posterior MIS endoscopic transforaminal
Posterior transfacet (pedicle sparing)
Thoracotomy
Posterolateral
Thoracoscopy
Thoracoscopy
Posterior MIS transforaminal
Laminectomy
Transpedicular
Costotransversectomy
Costotransversectomy, transpedicular
10 costotransversectomy, 4 lateral
Posterolateral microendoscopic
Thoracotomy
Mini-open thoracotomy
Thoracotomy
Thoracoscopy
Posterior transfacet
117
15
44
56
27
20
27
18
23
11
14
19
20
22
8
5
8
33
18
10
13
11
12
20
35
10
17
33
13
16
12
13
46
167
12
4
12
15
21
14
16
51
60
39
121
29
DISCUSSION
Symptomatic TDH is a surgical disease with a
dearth of evidence on which to base decisions in cases
with multiple surgical options. Results of our decision
analysis comparing open anterolateral transthoracic,
anterolateral thoracoscopic, posterior, and lateral approaches suggest posterior approaches result in the
highest HRQoL, as determined by complication data
from the published literature. The thoracoscopic approach results in the next highest HRQoL, closely followed by lateral approaches, and lastly open anterolateral
transthoracic procedures.
The most common posterior approach currently
used is the transpedicular approach. It was rst described
in 1978 to access anterolateral to the thecal sac and is
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Average QOL
SD
Scale Used
References
1.0
0.928
0.928
0.926
0.95
0.915
0.71
0.695
0.67
0
0
0.179
0.154
0.156
0
0.167
0.23
0.28
0.13
0
Consensus
SG
SG
SG
SG
SG
SG
VAS
EQ
Consensus
Sox et al21
Lega et al61
Lega et al 61
Lega et al 61
Danish et al62
Lega et al 61
King et al63
Sarna et al64
Gautschi et al65
Sox et al21
EQ indicates EuroQol; QOL, quality of life; SG, standard gamble, VAS, visual analog scale.
Copyright
Mean
Lateral
SD
Mean
327
0
4.0
0.3
1.8
0.0
1.8
0.0
0.0
0.0
0.0
2.4
Anterolateral Transthoracic
SD
Mean
193
0
1.1
0.3
0.7
0.0
0.7
0.0
0.0
0.0
0.0
0.9
0.5
11.5
0.0
2.1
0.5
1.0
0.0
6.3
0.5
0.5
2.1
SD
Thoracoscopic
Mean
335
0.5
2.3
0.0
1.0
0.5
0.7
0.0
1.7
0.5
0.5
1.0
2.1
22.5
0.0
0.7
13.8
0.9
0.0
3.2
0.9
0.7
4.0
SD
464
0.7
2.0
0.0
0.4
1.7
0.5
0.0
0.8
0.5
0.4
0.9
0.0
11.7
0.0
0.4
3.2
0.0
0.0
8.0
0.0
0.0
14.8
0.0
1.5
0.0
0.3
0.8
0.0
0.0
1.3
0.0
0.0
1.7
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Nayak et al
Mean
SD
Posterior
Thoracoscopic
Lateral
Anterolateral transthoracic
0.9911
0.9771
0.9744
0.9192
0.0037
0.0049
0.0072
0.0173
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CONCLUSIONS
Quality of life outcome measures have become an
increasingly important aspect of spine surgery. The
present study represents one of the rst applications of
HRQoL research to thoracic disk surgery. The results
of this decision analysis favor posterior over lateral approaches, and thoracoscopic over open anterolateral
approaches for the treatment of symptomatic TDHs,
which may guide surgeons in cases with multiple surgical
options. Symptomatic TDH requiring surgery is an uncommon entity, thus the learning curves associated with
various approaches cannot be ignored and likely play a
major role in outcomes. Future work is necessary to ascertain whether newer approaches, such as the recently
described mini-open and endoscopic posterior techniques,
may have risk/benet proles that ultimately supersede
those of traditional posterior approaches, and whether
enough cases are encountered by the average surgeon to
justify their adoption.
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