Chapter 4

1) 10%
2) Female: AB 46%, ab 46%, aB 4%, Ab 4%
Male: AB 50%, ab 50%
3) 1:2:1
4) B
5) 5 cM
6) 32% wildtype/wildtype, 18% wildtype/crossveinless, 18% purple/wildtype,
32% purple/crossveinless
7) Multiple crossovers happen
8) 2=1.28 P between .25 and .30, Evidence for presence in nonhomologous
chromosomes or far apart on the same one
9) 5.5%
10)
A) No, the problem says they are dominant and for them to both be
expressed they would have to be codominant if they were alleles of the same
gene so they must be different genes.
B) 2=1.03 P around .33, not linked
C) Must be far apart on chromosome
11)
A) Dd
B) (A- dd B-)/(aa D- bb)
C) Dd and Bb
D) 11 cM
E) The same recombination frequency would indicate a greater distance in
map units because not all the expected double recombinations would be
present due to shielding related to distance.
12)
A) Pr v bm, pr-v = .207 v-bm = .415, .896, .104
B) Map distance is only a good estimate for under 10 cM
13)
A) It is most likely hd A/HD a
B) 90%
C) 10%
14)
A) 1:2:1 of F:FS:S with no O
B) No, there are 25 O types.
C) You are actually looking at a dihybrid cross of two unlinked genes and
would expect a 9:3:3:1 ratio of FS:F:S:O
D) 2=2.66 P=.5 (Good hypothesis)
15)
Distance to centromere = 5.5 cM
16)
6 double recombinant, 144 single switching at ci-p, 194 single
switching at o-ci, 656 parental
17)
A) A-B no linkage (196 is near 214), B-C no linkage (132 is near 124),
no A-C NPDs so PD>>NPD and A-C is linked
B) 18 cM
18)
A) 1 (.06 + .14) = .8
B) .06
C) .14
D) Cannot occur with complete interference
E) PD - .8, TT - .2, NPD 0
19)
Repulsion, 20%
20)
A) (++unc)/(dordpy+)
B) dor 20.6 cM dpy 15 unc

C) No double recombinants so 1
Chapter 4
1) X inactivation is incomplete
2) The Y chromosome has homologous sections that exchange genes with the X
chromosome the same way autosomal chromosomes would.
3) 47 Down syndrome 45 Turners syndrome
4) Incomplete X inactivation like in Calico cats occurs except instead of
differently colored patches it is patches of different resistivity
5) .5*.5=.25
6) No, you would expect half and half
7) No, suppression is incomplete but products are not viable
8) XXY male with X from mother as orange and X from father as black.
Nondisjunction occurs in father.
9) d/c a f b e
10)
u v y (w/x) z, do a three point cross
11)
bacedf
12)
Usually occurs from nondisjunction of chromosome 21, but this was
from a Robertsonian translocation
13)
She got the colorblind carrying X chromosome from the father and
none from the mother so the mother must have had a nondisjunction
14)
A region of unequal crossover. This suggests same direction.
15)
Robertsonian translocation of acrocentric chromosomes.
16)
A) 12% B) 8%
17)
A) 11.9% B) 1:1:1:1
18)
Cross haploids of first two species to make sterile hybrid. It
endoreplicates and crosses with a third specie. It then again undergoes
endoreplication. Zygote of the three has n = 18 and 2n = 36 after
endoreplication.
19)
Two percent segregation implies 1 cM map length as opposed to 10 cM.
Pericentric inversion returns it to 10 cM.
20)
A (c/e) g b h d f
21)
Cabgfde
Chapter 5
1) There is overhang at restriction sites of cut DNA that easily latch on to
complementary segments
2) A) 5-ACGCGT-3
B) 5-ATCGAT-3
C) 5-AGCT-3
D) 5-GATATC-3