Beruflich Dokumente
Kultur Dokumente
4 August 2009
G1BE209 - Respiratory MCQ
A - TYPES
The image below shows the cut surface of a lung in a 65 year-old patient from Gauteng who died in
a cachectic state after an illness lasting only a few months.
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G1BE209 - Respiratory MCQ
2.
The images below show the lung and heart of a patient in whom a lung condition has given rise to a
lesion in the heart.
Which of the following is the most likely process by which this occurred?
a. Direct spread
b. Emboli from the right atrium
c. Lymphatic spread
d. Pyaemia via the pulmonary artery
e. Septicaemia
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G1BE209 - Respiratory MCQ
3.
The image below is a sagittal section of the left lung taken from a patient who had previously worked
in a mine.
4.
When IgE on a mast cell FcE receptor is cross-linked by an allergen, the mast cell responds by:
a. undergoing apoptosis.
b. presenting antigen to Th cells.
c. secreting more IgE.
d. secreting histamine.
e. stimulating macrophage phagocytosis of coated antigen.
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G1BE209 - Respiratory MCQ
5.
Of the following choices, identify the statement which commonly defines the term "strong
anthropocentrism".
a. Human beings prioritise their satisfaction of immediate wants and desires, no matter how
trivial, above the wants and desires of other sentient animals.
b. Human beings are intrinsically valuable. This means that we are valuable in a way that
transcends our utility to other beings.
c. Human beings are the centre of the universe. As such, we are concerned with the
satisfaction of our wants, needs, and desires above all else.
d. Human beings are the top of the evolutionary scale. Because of this, we have been given
dominion over all living things.
e. Human beings are capable of feeling pleasure and pain. This sets us apart from lower life
forms.
6.
X TYPES
In obstructive lung disease there is
a. an increased FEV1
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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G1BE209 - Respiratory MCQ
7.
a. decreased FEV1/FVC
True
False
Don't know
True
False
Don't know
c. decreased PEFR
True
False
Don't know
True
False
Don't know
True
False
Don't know
8.
True
False
Don't know
True
False
Don't know
c. residual volume
True
False
Don't know
True
False
Don't know
e. FEV1/FVC ratio
True
False
Don't know
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G1BE209 - Respiratory MCQ
9.
True
False
Don''t know
True
False
Don''t know
c. residual volume
True
False
Don''t know
d. predicted FVC
True
False
Don''t know
e. FEV1/FVC ratio
True
False
Don''t know
10. The affinity of haemoglobin for oxygen increases with an increase in plasma
a. carbon dioxide partial pressure
True
False
Don't know
b. pH
True
False
Don't know
True
False
Don't know
True
False
Don't know
e. temperature
True
False
Don't know
a) Incorrect: PCO2 produces a right shift in the O2-Hb saturation curve lower affinity
b) Correct: pH produces a left shift in the O2-Hb saturation curve affinity
c) Correct: PaO2 directly increases the affinity of Hb to oxygen (shape changes)
d) Incorrect: CO binds competitively to Hb displacing O2
e) Incorrect: temp produces a right shift in the O2-Hb saturation curve lower affinity
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G1BE209 - Respiratory MCQ
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
a)
b)
c)
d)
e)
Incorrect: better blood flow than ventilation at the base of the lung
Incorrect: Pulmonary shunt is unventilated blood flow Q and V ratio
Correct: Physiological dead space is unperfused alveoli Q and V ratio
Correct: exercise = VA (10 times or more), smallerQ Q but V ratio
Correct: VA ratio
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
e. urine pH
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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G1BE209 - Respiratory MCQ
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
(a) Correct: Carbon monoxide poisoning results in reduced oxygen carrying capacity of
haemoglobin causing reduced tissue oxygenation
(b) Correct: any condition that reduces atmospheric oxygen will eventually lead to
reduced oxygen in the tissues
(c) Correct: hypoxic hypoxia causes pulmonary vasoconstriction which causes increased
work load to the right heart leading to right heart failure
(d) Correct: left heart failure causes reduced blood flow leading to stagnant hypoxia
(e) Incorrect: hypoxic hypoxia leads to stimulation of erythropoietin secretion
True
False
Don't know
b.
True
False
Don't know
c.
cyanide poisoning
True
False
Don't know
d.
heart failure
True
False
Don't know
e.
True
False
Don't know
(a) Correct: reduced haemoglobin leads to reduced tissue oxygenation hence hypoxia
(b) Correct: Vitamin B12 deficiency cause haemolysis of red blood cells leading to reduced
tissue oxygenation
(c) Incorrect: Cyanide poisoning inhibits oxidative phosphorylation leading to histotoxic
anaemia
(d) Incorrect: Heart failure leads to reduced cardiac output causing stagnant hypoxia
(e) Correct: reduced rbc synthesis leads to reduced tissue oxygenation
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G1BE209 - Respiratory MCQ
PaO2
True
False
Don't know
b.
oxidative phosphorylation
True
False
Don't know
c.
True
False
Don't know
d.
blood flow
True
False
Don't know
e.
True
False
Don't know
17. The tympanic membrane is a clinically important structure. Which of the following
statements about its anatomy are true and which are false?
a. It is lined internally by a mucous membrane.
True
False
Don't know
True
False
Don't know
c. It is circular in shape.
True
False
Don't know
d. It slopes inferomedially.
True
False
Don't know
True
False
Don't know
18. The middle ear is an important site of infections, particularly in children. Infections from
the middle ear can spread to the mastoid bone and to the middle cranial fossa and can
also result in conductive deafness. Which of the following statements about the middle
ear are true and which are false?
a. The tympanic cavity is joined to the oropharynx
by the pharyngotympanic tube.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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19. A number of critically important anatomical structures are found in the mediastinum.
Which of the following statements about the mediastinum are true and which are false?
a. The trachea bifurcates at the level of the sternal
angle.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
20. The diaphragm, ribs and pleural cavity play critical roles in the process of respiration.
Which of the following statements about these structures and their function are true
and which are false?
a. The diaphragm attaches to the lower 6 ribs and
costal cartilages.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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21. The paranasal sinuses are clinically important as sites of infection and even of
malignancy (particularly in smokers). Which of the following statements about these
sinuses are true and which are false?
a. Each maxillary sinus opens into the inferior
meatus of the nasal cavity.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
b.
True
False
Don't know
c.
True
False
Don't know
d.
True
False
Don't know
e.
True
False
Don't know
23. Non-steroidal therapy plays a vital part in the treatment of asthma and COPD. Which of
the following statements about this type of therapy are correct?
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
e.
True
False
Don't know
a.
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G1BE209 - Respiratory MCQ
24. Which of the following statements regarding the use of antibacterial drugs in respiratory
infections are correct?
a. Azithromycin is contraindicated in penicillinallergic patients.
True
False
Don't know
True
False
Don't know
c.
True
False
Don't know
d.
True
False
Don't know
e.
True
False
Don't know
25. Symptoms related to the respiratory system often have allergic origins and therefore
require treatment with antihistamine drugs. Which of the following statements
regarding antihistamine therapy are correct?
a. Diphenhydramine causes less sedation than
loratadine.
True
False
Don't know
True
False
Don't know
c.
True
False
Don't know
True
False
Don't know
True
False
Don't know
26. The full and correct management of tuberculosis disease is of critical importance in
South Africa today. Which of the following statements about the agents used against
Mycobacterium tuberculosis are correct?
a. Ethambutol inhibits mycobacterial DNAdependent RNA polymerase
True
False
Don't know
True
False
Don't know
c.
True
False
Don't know
True
False
Don't know
True
False
Don't know
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27. Respiratory disease is a major public health concern at the start of the 21st century.
Which of the following statements about the public health aspects of these diseases in
Africa is/ are correct?
a. Respiratory diseases account for approximately
20% of deaths in Africa annually.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
28. Tuberculosis is a major public health problem in the developing world including South
Africa. It is essential that the diagnosis, management and control of TB should be
optimally carried out. Which of the following statements about TB control are correct?
a. Robert Kochs postulates set out the criteria for
determining the causative agent in an infectious
disease.
True
False
Don't know
True
False
Don't know
c.
The Labour Relations Act is an important piece
of legislation that can be used in addressing
occupational determinants of TB.
True
False
Don't know
d.
In line with the Stop TB strategy, the global
target for reduction of TB incidence by 2015 is 75%
of 1990 levels.
True
False
Don't know
e.
The City of Johannesburg has consistently
managed to achieve a cure rate of above 70% since
2006.
True
False
Don't know
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29. Exposure of workers to asbestos fibres in the mining and industrial sectors, as well as in
housing, has been one of the environmental health disasters of the past century.
Which of the following statements about asbestos related disease is/ are correct?
a. As asbestos has been banned in over 40
countries a subsequent reduction in occupational
lung cancers can be expected in the next decade.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
30. Occupational disease remains a public health problem worldwide and also in South
Africa, and one which medical practitioners in working class communities are likely to
encounter on a regular basis. Which of the following statements about occupational
diseases is/ are correct?
a. A doctor should suspect that a condition is
occupational when symptoms are better on
weekends when the patient is not at work.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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31. Following on a decade of relative neglect the World Health Organisation is again
stressing the need to put the Primary Health Care (PHC) philosophy at the centre of
health service provision in all member countries. Which of the following statements
relating to health and Primary Health Care in South Africa are correct?
a. The right to health and health care is a basic
right enshrined in the South Africa Constitution.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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G1BE209 - Respiratory MCQ
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
34. Which of the following are vaccine preventable diseases that are also notifiable to the
Department of Health in South Africa?
a. Polio
True
False
Don't know
True
False
Don't know
True
False
Don't know
d. Meningococcal disease
True
False
Don't know
e. Mumps
True
False
Don't know
35. A 22 year old male presents following a motor vehicle accident. He has multiple facial
lacerations and is confused. In their preparation for the patient, the Emergency
Department Team tasked with his care make use of Universal Precautions. Which of the
following would be considered Universal Precautions?
True
False
Don't know
True
False
Don't know
c. Shoe covers
True
False
Don't know
True
False
Don't know
True
False
Don't know
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36. A victim of a hijack is brought to the Emergency Room by paramedics. He has been
shot in the face. His vitals signs are as follows: Glasgow Coma Scale 15/15 (E4,M6,V5);
blood pressure 139/87 mm Hg; heart rate 107 b.p.m.; respiratory rate 22/minute.
Which of the following statements about his initial management are correct?
a. He may need definitive airway management due
to profuse bleeding.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
37. A young mother brings her 18 month old child to the Emergency Room with severe
dyspnoea. On questioning the mother you find out that the child had been eating
Smarties when the problem started. In this situation emergency management and an
accurate diagnosis are clearly essential. Which of the following statements about
emergency management and diagnosis are correct?
a. Supplemental oxygen should immediately be
applied.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
38. Which of the following processes are consequences of mast cell activation?
a. Bronchoconstriction
True
False
Don't know
b. Cyotokine production
True
False
Don't know
c. Leukotriene synthesis
True
False
Don't know
d. Opsonisation
True
False
Don't know
e. Vasodilation
True
False
Don't know
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G1BE209 - Respiratory MCQ
39. Which of the following are proven risk factors for the development of active TB infection
in South Africa?
a. Adolescence
True
False
Don't know
b. Coal mining
True
False
Don't know
True
False
Don't know
d. Latent TB infection
True
False
Don't know
e. Cigarette smoking
True
False
Don't know
40. A 15 year old boy presents complaining of a tight chest for the past 2 days, with a
nocturnal cough. He has an inhaler that he uses intermittently. He is afebrile. Which of
the following clinical features would you expect to find on examination?
a. Pleural rub
True
False
Don't know
True
False
Don't know
c. Stridor
True
False
Don't know
True
False
Don't know
e. Pulsus paradoxus
True
False
Don't know
41. Upper respiratory tract infections are among the most common conditions that general
medical practitioners have to deal with. Indicate which of the following statements
about upper respiratory tract infections are correct
a. 85% of children with acute otitis media and
otalgia are free of pain within 24 hours without
receiving antibiotics..
True
False
Don't know
True
False
Don't know
True
False
Don't know
d.
True
False
Don't know
True
False
Don't know
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G1BE209 - Respiratory MCQ
Of the following choices, identify the statement which commonly defines the term strong
anthropocentrism.
a.
b.
c.
d.
e.
Human beings prioritise their satisfaction of immediate wants and desires, no matter
how trivial, above the wants and desires of other sentient animals.
Human beings are intrinsically valuable. This means that we are valuable in a way that
transcends our utility to other beings.
Human beings are the centre of the universe. As such, we are concerned with the
satisfaction of our wants, needs, and desires above all else.
Human beings are the top of the evolutionary scale. Because of this, we have been
given dominion over all living things.
Human beings are capable of feeling pleasure and pain. This sets us apart from lower
life forms.
Answer: c
42. A new Public Health (PH) paradigm in ethics is being advanced because the existing one
is flawed. Which of the following are necessary components of such a new paradigm in
Public Health ethics?
a. It should hold that the state has the final
responsibility for Public Health.
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
True
False
Don't know
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G1BE209 - Respiratory MCQ
43. R TYPES
A.
B.
C.
D.
E.
F.
G.
H.
I.
J.
K.
L.
M.
N.
O.
Acute bronchiolitis
Adenocarcinoma
Bagassosis
Bronchopneumonia
Byssinosis
Crohns disease
Emphysema
Farmers lung
Lobar pneumonia
Metastatic tumour
Miliary tuberculosis
Sarcoid
Silicosis
Small airways disease
Squamous carcinoma
For each of the sets of images below, select the condition from the list A to N above
that was most likely involved in the resulting pathology.
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G1BE209 - Respiratory MCQ
43. SET 1
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
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G1BE209 - Respiratory MCQ
44. SET 2
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
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G1BE209 - Respiratory MCQ
45. SET 3
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
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Bronchiectasis
Bronchiolar-alveolar carcinoma
Bronchogenic carcinoma
Bullous centrilobular emphysema
Cor pulmonale
Diffuse alveolar damage
Hilar lymphadenopathy
Isolated organ tuberculosis
Lung abscess
Metastatic tumour
Panlobular emphysema
Paraseptal emphysema
Phlebo-thrombosis of the deep calf veins
Poorly-formed granulomas
Small airways disease
Small cell carcinoma
Uraemic pneumonitis
For each of the scenarios listed below choose the pathological condition listed which
most accurately explains the patients symptoms/disease (note that answers may be
used more than once):
46. A 60 year old female patient on treatment for chronic obstructive airways disease
developed a sudden sharp stabbing pain in the left chest associated with haemoptysis
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
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G1BE209 - Respiratory MCQ
47. A male living in shack dwelling is trapped inside when the house is accidentally catches
fire. He is admitted to hospital with severe burns and dies a few days later.
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
48. A young male is being investigated for progressive dyspnoea. He is found to have
decreased levels of alpha 1-antitrypsin activity in a sample of his peripheral blood.
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
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G1BE209 - Respiratory MCQ
49. A 65 year old male is admitted in cardiac failure. He has been a cigarette smoker for
many years and more recently has had a productive cough for the past 3 years. A
radiograph of his chest confirms the presence of right ventricular hypertrophy.
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
50. A 65 year old female is admitted to hospital for investigation of productive cough and
more recently several episodes of haemoptysis. In addition, she also admits that she has
had a increasingly severe lower back pain over the passed few months. A radiograph of the
chest is clear, but a radiograph of her lumbar spine is highly suggestive of her primary
pathology.
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
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