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Master of Engineering and Doctor of Philosophy Programs

(International Program)
New Curriculum 2012
Name of Educational Institution
Campus/ Faculty/ Department

Burapha University
Faculty of Engineering

Section 1 : General Information


1. Code and Name of Curriculum:

Master of Engineering Program in


Bioengineering (International Program)
Doctor of Philosophy Program in
Bioengineering (International Program)

2. Name of Degree and Major:

Master of Engineering (Bioengineering)


Doctor of Philosophy (Bioengineering)
M.Eng. (Bioengineering)
Ph.D. (Bioengineering)

Degree in Abbreviation in English:

3. Major
3.1 Biomaterials Engineering
3.2 Biomedical Engineering
3.3 Bioprocess Engineering
3.4 Bioelectronics, Bioimaging and Bioinformatics
3.5 Biopharmaceutical Engineering
3.6 Stem Cell and Biomolecular Engineering
4. Credit Requirements
4.1 Master of Engineering
Scheme A1: 36 credits
Scheme A2: Not less than 36 credits
4.2 Doctor of Philosophy
Scheme 1.1: 48 credits
Scheme 1.2: 72 credits
Scheme 2.1: Not less than 48 credits
Scheme 2.2: Not less than 72 credits

5. Curriculum Model
5.1 Model: Master and Doctoral Degree Levels
5.2 Language of Instruction: English
5.3 Admission of Applicants: Both Thai and foreign applicants are admitted.
5.4 Cooperation with Other Institutions: The program is specifically operated by
the Faculty of Engineering.
5.5 Degree Conferred to the Graduates: The graduates will be conferred only
by one discipline.
6. Lecturers Responsible for the Curriculum
1. Mr. Witawat Jangiam
Ph.D. (Biochemistry), Mahidol University, Thailand 2008
B.Sc. (Medical Technology), Chulalongkorn University, Thailand 2002
Academic Position: Assistant Professor
2. Ms. Yanisa Laoong-u-thai
Ph.D. (Biochemistry), Prince of Songkla University, Thailand 2009
B.S. (Biotechnology), Prince of Songkla University, Thailand 2004
Academic Position: Lecturer
3. Ms. Jittima Charoenpanich
Ph.D (Natural Science and Technology), Okayama University, Japan, 2006
M.Sc. (Biochemistry), Chulalongkorn University, Thailand 2002
B.Sc. (Biochemistry), Chulalongkorn University, Thailand 1999
Academic position: Assistant Professor
4. Mrs. Mayuree Tantisira
Ph.D (Pharmacology), Gothenburg University, Sweden 1990
M.Sc. (Pharmacology), Mahidol University, Thailand 1975
B.Sc. (Pharmacy), Chulalongkorn University, Thailand 1973
Academic position: Associate Professor
7. Instructional Sites
At the Faculty of Engineering, Burapha University, Bangsaen, Chonburi
8. External Situations or Essential Development factors for Consideration in
Curriculum Planning
8.1 Existing Situations or Economic Development
Thailand nowadays, biotechnological based businesses have been expanded
rapidly. There are changes in the development of quality of life. For example, new
agricultural technology is very sophisticated and significant to increase the productivity

and help solve problems in the future due to the lack of food. Medical technology
provides high accuracy of various applications including monoclonal antibody test kit,
vaccine for new diseases, etc. Moreover, new renewable energies such as bioethanol,
biodiesel derived from various sources of raw materials are developed by the rapid
growth of biotechnological research integrated with the knowledge of engineering. This
can be said that the knowledge of engineering integrated with life science becomes
important for everyday life. The OECD forecasts the new global economics will swift
into bioeconomics in year 2030. This future trend of economics will change Thailand as
the country is agricultural based economics which needs biotechnology and
engineering research for developing the country.
8.2 Existing Situations of Social and Cultural Development
Many organizations in Thailand are concerned about the growth of
biotechnology research which plays an important role in developing the country.
These concerns can be seen in the strategic plan of NSTDA (2007-2011), strategic plan
in science and technology provided by the Ministry of Science and Technology (20032013), strategic plan for economics and socials no. 11 (2012-2016), etc. All plans
emphasize on the development in both human resources and knowledge of new
trend in biotechnology integrated with engineering based research to compete with
the changes in the future global economics.
9. The impact from Items 8.1 and 8.2 on Curriculum Development and
Relationship to the Universitys Mission.
9.1 Curriculum Development
Burapha University aims to be national research university in next 10
years as targeted in the strategic plan. To achieve this goal, the increases in the
number of postgraduate students and lecturer with a PhD degree are significant and
needed to well plan in long term.
The Faculty of Engineering is concerned about this change in the future.
We need to prepare the foundation and infrastructure of both human resources and
program of study. Bioengineering program is nowadays very significant and a program
integrating with life science to enhance the quality of life and strengthen the
economics of the country. Although this program is new to the faculty, a lot of
lecturers have been working on research related with biological based such as
ergonomic study at the department of industrial engineering, research on medical
devices and image and signals processing at the department of electrical
engineering, research on bioenergy at the department of chemical engineering etc. The
faculty therefore starts up this program to strengthen our research staffs and academic
staffs to be prepared for the new trend of biotechnological based research in the

future. At the beginning, master and doctoral programs are focused and then the
bachelor program will be developed in collaboration with the well-known university.
9.2 Relationship to the Universitys Mission.
This program is multidisciplinary program integrated between
engineering and life sciences such as biochemistry, biophysics, biotechnology,
medicine, pharmacy and public health to promote the new knowledge that help
strengthen research and teaching in bioengineering-based study.
10. Integration with Curriculums Offered by Other Faculties and Departments
10.1 Subject category/ Courses in this program offered by other Faculties/
Departments/ Other Programs
None
10.2 Courses offered for other Faculties/ Departments/ Programs
None
10.3 Management
None
Section 2: Specific Information of the Curriculum
1. Philosophy, Significance, and Objectives of the Curriculum
Philosophy of the Curriculum
The curriculum of the Master of Engineering combined with the Doctor of
Philosophy in Bioengineering Program (International Program) is mainly emphasized on
instruction of in-depth theories, research and academic search for creating the new
body of knowledge in the field of integrated engineering with life science.
Significance
The 10th National Economic and Social Development Plan (2007 2011)
stipulates the foundation of building national capitals in all aspects, for instance, social
capital, economic capital, natural resources capital with strong and sustainable
environment., and human capital based on human resource- centered development.
The philosophy of sufficiency economy is to be applied as a practical guideline for
leading the way towards a peaceful and happy society. Moreover, the future economy
will shift to Bioeconomy in year 2030 as predicted by the OECD. The biological based
technology is included in this plan as the country is agricultural based.
Objectives of the Curriculum
1.1 To create the advanced postgraduates in bioengineering having high
potential in the sustainably integration of research and development
between engineering and life science.

1.2

To enhance and strengthen the research and development in


bioengineering that helps develop and serve the countrys and
universitys strategies.

Section 3 : Education Provision Management System, Implementation, and


Curriculum Structure
1. Education Provision Management System
1.1 System
There are two semesters in each academic year.
1.2 Summer Session
Summer session is not required.
1.3 Credit Equivalence in the Semester System
None
2. Implementation
2.1 Duration of Instruction
This program is offered during office hours on the weekdays. However,
weekends are optional if required.
2.2 Entry Requirements
General Requirement: The applicants must meet the basic requirement as
stated in Burapha University Regarding Graduate Studies of B.E. 2552
Specific requirements:
Master of Engineering in Bioengineering Program
i) Applicants with the bachelor of engineering, science, technology, medicine,
pharmacy or all fields of life science background are eligible. Applicants
with other fields of the aforementioned will be approved by the program
committees.
ii) Applicants must pass the acceptable English tests: minimum required TOEFL
500 or IELTS 5.5 or CU-TEP equivalent to TOEFL 500.
Doctor of Philosophy in Bioengineering Program
Scheme 1.1: Applicants with the master of engineering, science, technology,
medicine, pharmacy or all fields of life science background and having a GPA of 3.50 or
above are eligible. All applicants must pass the evaluation process of the program
committees.
Scheme 1.2: Applicants with the bachelor of engineering, science,
technology, medicine, pharmacy or all fields of life science background and having

very good academic record or holding at least second-class honors degree are eligible.
All applicants must pass the evaluation process of the program committees.
Scheme 2.1: Applicants with the master of engineering, science, technology,
medicine, pharmacy or all fields of life science background and having a GPA of 3.25 or
above are eligible.
Scheme 2.2: Applicants with the bachelor of engineering, science, technology,
medicine, pharmacy or all fields of life science background and having very good
academic record or holding at least second-class honors degree are eligible.
All applicants must pass the acceptable English test: minimum required
TOEFL 525 or IELTS 6.0 or CU-TEP equivalent to TOEFL 525.
2.3 Problems of New-coming Students
Applicants with engineering backgrounds may face the problems of basic
life science knowledge.
2.4 Limitations or Problem Solving Strategies for Newcoming Students
To achieve the criteria stated in item 2.3, the applicants are required to take
the following subjects upon the approval of program committees.
506401
506402
506403

Cell and Molecular Biology for Bioengineering


Physiology for Bioengineering
Organic Chemistry and Biochemistry for Bioengineering

3(3-0-6)
3(3-0-6)
3(3-0-6)

2.5 Studying System


Classroom Setting
Distance learning through printed media
Distance learning through hybrid media
Distance learning through E-learning
Distance learning through the Internet
Others (specify)
2.6 Credit and Course Transfer and Inter-university Enrollment (if available)
2.6.1 Students who studied at other higher education institutions can
have their credits earned transferred according to Burapha University Regarding
Graduate Studies of B.E. 2552.
2.6.2 Students can enroll in some courses at other universities and
have credits transferred according to Burapha University Regarding Graduate Studies of
B.E. 2552

3. Curriculum and Course Instructors


3.1 Curriculum of Master of Engineering in Bioengineering Program
3.1.1 Credit Requirements
At least 36 credits are required.
3.1.2 Structure of the Curriculum
Type A1: Total credits required are 36 credits.
i)
Compulsory courses Non-credts
ii)
Thesis
36 credits
Type A2: At least 36 credits are required.
i)
Compulsory courses Non-credits
ii)
Core courses
9 credits
iii)
Electives
15 credits
iv)
Thesis
12 credits
3.1.3 Courses and Credit Hours
1. Compulsory courses (Non-credits)
506591
Research Methods
1(1-0-2)
Note
Students must attend the seminars provided by the
Faculty
2. Core Courses
506511
Bioengineering and Applications
3(3-0-6)
506512
System Bioengineering
3(3-0-6)
506513
Bioeconomics and Entrepreneurship in Biotechnology
3(3-0-6)
3. Elective courses
At least 15 credits of elective courses are selected from any group with the approval
by research advisor
Biomaterials Engineering
506621
Biomaterials Engineering
3(3-0-6)
506622
Design and Applications of Biomaterials
3(3-0-6)
506623
Characterization of Biomaterials
3(3-0-6)
506624
Polymeric Biomaterials
3(3-0-6)
506625
Advanced Bioceramics
3(3-0-6)
506626
Advanced Surface Engineering
3(3-0-6)
506628
Special Topics in Biomaterials Engineering I
3(3-0-6)
506629
Special Topics in Biomaterials Engineering II
3(3-0-6)
Biomedical Engineering
506631
Modeling in Biomedical Engineering
3(3-0-6)
506632
Biomedical Instrumentation
3(3-0-6)
506633
Metabolic System and Regulation
3(3-0-6)

506634
Design of Medical Devices and Implants
506635
Rehabilitation Engineering and Assistive Technology
506638
Special Topics in Biomedical Engineering I
506639
Special Topics in Biomedical Engineering II
Bioprocess Engineering
506641
Biochemical Engineering
506642
Bioseparation Engineering
506643
Metabolic Engineering
506644
Biological System Modeling and Controls
506645
Biotransport Phenomena
506646
Biological Reaction Engineering and Bioreactor Design
506647
Enzymatic Engineering
506648
Special Topics in Bioprocess Engineering I
506649
Special Topics in Bioprocess Engineering II
Bioelectronics, Bioimaging and Bioinformatics
506651
Advanced Mathematics for Bioengineering
506652
Algorithms for Functional Genomics
506653
Computational Biology and Bioinformatics
506654
Machine Learning
506655
Signals and Systems
506656
Statistical Signal Processing in Biomedical Engineering
506657
Digital Image Processing
506658
Special Topics in Bioelectronics, Bioimaging and
Bioinformatics I
506659
Special Topics in Bioelectronics, Bioimaging and
Bioinformatics II
Biopharmaceutical Engineering
506661
Pharmaceutical Process Design
506662
Pharmaceutical Kinetics, Thermodynamics and Transport
Processes
506663
Pharmaceutical Materials and Pharmaceutical Organic
Nanotechnology
506664
Nanotechnology-based Drug Design and Delivery
506665
Structure and Function of Drugs
506666
Chemical Tools for Assessing Biological Function
506668
Special Topics in Biopharmaceutical Engineering I
506669
Special Topics in Biopharmaceutical Engineering II
Stem Cell and Biomolecular Engineering

3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)

506671
506672
506673
506674
506675
506676

Molecular and Genetic Engineering


Protein Engineering
Cell and Protein Interaction
Tissue Engineering and Stem Cell Processing
Tissue, Cellular and Molecular Basis of Disease
Stem Cells in Organogenesis, Carcinogenesis and
Atherogenesis
506678
Special Topics in Stem Cell and Biomolecular Engineering
I
506679
Special Topics in Stem Cell and Biomolecular Engineering
II
Note: Students are eligible to enroll other courses at any university
other countries upon the approval of engineering faculty board.
4. Thesis
506697
Thesis
506699
Thesis

3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
in Thailand or
36(0-0-108)
12(0-0-36)

3.1.4 Plan of Study


Type A1
506591
506697

1st year Fall semester


Research Methods
Thesis
1st year Spring semester

506697

Thesis
2nd year Fall semester

506697

Thesis
2nd year Spring semester

506697

Type A2
506591
506511

Thesis

Non-credit
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
Total 36 credits

1st year Fall semester


Research Methods
Bioengineering and Applications

Non-credit
3(3-0-6)

506512
506513

1st year Spring semester


506xxx
506xxx
506xxx

Elective Course I
Elective Course II
Elective Course III
2nd year Fall semester

506699
506xxx

Thesis
Elective Course IV
2nd year Spring semester

506699
506xxx

3(3-0-6)
3(3-0-6)
Total credits 9

System Bioengineering
Bioeconomics and Entrepreneurship in Biotechnology

Thesis
Elective Course V

3(3-0-6)
3(3-0-6)
3(3-0-6)
Total credits 9
6(0-0-18)
3(3-0-6)
Total credits 9
6(0-0-18)
3(3-0-6)
Total credits 9
Total 36 credits

3.2 Curriculum of Doctor of Philosophy in Bioengineering Program


3.2.1 Credit Requirements
Scheme 1.1: 48 credits are required.
Scheme 1.2: 72 credits are required.
Scheme 2.1: At least 48 credits are required.
Scheme 2.2: At least 72 credits are required.
3.2.2 Structure of the Curriculum
Sheme 1.1: Total credits required are 48 credits.
i)
Compulsory courses Non-credit
ii)
Dissertation
48 credits
Scheme 1.2: Total credits required are 72 credits
i)
Compulsory courses Non-credit
ii)
Dissertation
72 credits
Scheme 2.1: At least 48 credits are required.
i)
Compulsory courses Non-credit
ii)
Core courses
3 credits
iii)
Electives
9 credits
iv)
Dissertation
36 credits
Scheme 2.2: At least 72 credits are required.
i)
Compulsory courses Non-credit
ii)
Core courses
12 credits
iii)
Electives
12 credits

iv)
Dissertation
48 credits
3.2.3 Courses and Credit Hours
1. Compulsory courses (Non-credits)
506591
Research Methods
1(1-0-2)
Note
Students must attend the seminars provided by the
Faculty.
2. Core Courses
Scheme 2.1
506711
Advanced Topics in Bioengineering
3(3-0-6)
Scheme 2.2
506511
Bioengineering and Applications
3(3-0-6)
506512
System Bioengineering
3(3-0-6)
506513
Bioeconomics and Entrepreneurship in Biotechnology
3(3-0-6)
506711
Advanced Topics in Bioengineering
3(3-0-6)
3. Elective courses
Scheme 2.1 and 2.2 require not less than 9 and 12 credits of elective courses,
respectively, from any group with the approval of research advisor.
Biomaterials Engineering
506621
Biomaterials Engineering
3(3-0-6)
506622
Design and Applications of Biomaterials
3(3-0-6)
506623
Characterization of Biomaterials
3(3-0-6)
506624
Polymeric Biomaterials
3(3-0-6)
506625
Advanced Bioceramics
3(3-0-6)
506626
Advanced Surface Engineering
3(3-0-6)
506628
Special Topics in Biomaterials Engineering I
3(3-0-6)
506629
Special Topics in Biomaterials Engineering II
3(3-0-6)
Biomedical Engineering
506631
Modeling in Biomedical Engineering
3(3-0-6)
506632
Biomedical Instrumentation
3(3-0-6)
506633
Metabolic System and Regulation
3(3-0-6)
506634
Design of Medical Devices and Implants
3(3-0-6)
506635
Rehabilitation Engineering and Assistive Technology
3(3-0-6)
506638
Special Topics in Biomedical Engineering I
3(3-0-6)
506639
Special Topics in Biomedical Engineering II
3(3-0-6)
Bioprocess Engineering
506641
Biochemical Engineering
3(3-0-6)
506642
Bioseparation Engineering
3(3-0-6)
506643
Metabolic Engineering
3(3-0-6)

506644
Biological System Modeling and Controls
506645
Biotransport Phenomena
506646
Biological Reaction Engineering and Bioreactor Design
506647
Enzymatic Engineering
506648
Special Topics in Bioprocess Engineering I
506649
Special Topics in Bioprocess Engineering II
Bioelectronics, Bioimaging and Bioinformatics
506651
Advanced Mathematics for Bioengineering
506652
Algorithms for Functional Genomics
506653
Computational Biology and Bioinformatics
506654
Machine Learning
506655
Signals and Systems
506656
Statistical Signal Processing in Biomedical Engineering
506657
Digital Image Processing
506658
Special Topics in Bioelectronics, Bioimaging and
Bioinformatics I
506659
Special Topics in Bioelectronics, Bioimaging and
Bioinformatics II
Biopharmaceutical Engineering
506661
Pharmaceutical Process Design
506662
Pharmaceutical Kinetics, Thermodynamics and Transport
Processes
506663
Pharmaceutical Materials and Pharmaceutical Organic
Nanotechnology
506664
Nanotechnology-based Drug Design and Delivery
506665
Structure and Function of Drugs
506666
Chemical Tools for Assessing Biological Function
506668
Special Topics in Biopharmaceutical Engineering I
506669
Special Topics in Biopharmaceutical Engineering II
Stem Cell and Biomolecular Engineering
506671
Molecular and Genetic Engineering
506672
Protein Engineering
506673
Cell and Protein Interaction
506674
Tissue Engineering and Stem Cell Processing
506675
Tissue, Cellular and Molecular Basis of Disease
506676
Stem Cells in Organogenesis, Carcinogenesis and
Atherogenesis
506678
Special Topics in Stem Cell and Biomolecular Engineering

3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)

I
506679
Special Topics in Stem Cell and Biomolecular Engineering
II
Note: Students are eligible to enroll other courses at any university
other countries upon the approval of engineering faculty board.
4. Dissertation
506898
Dissertation
506899
Dissertation
506998
Dissertation
506999
Dissertation

3(3-0-6)
in Thailand or
48(0-0-144)
72(0-0-216)
36(0-0-108)
48(0-0-144)

Course Code Numbers


506 indicates Bioengineering program
The 4th number indicates level of study (5 and 6 for master level, 7-9 for doctoral level)
The 5th number indicates sub-group of bioengineering program
0 indicates seminar and foundation subjects
1 indicates core courses
2 indicates biomaterials engineering group
3 indicates biomedical engineering group
4 indicates bioprocess engineering group
5 indicates bioelectronics, bioimaging and bioinformatics
6 indicates biopharmaceutical engineering group
7 indicates stem cell and biomolecular engineering group
The last number indicates the series of subject in each group

3.2.4 Plan of study


Scheme 1.1
506591
506898

1st year Fall semester

Research Methods
Dissertation
1st year Spring semester

506898

Dissertation
2nd year Fall semester

506898

Dissertation
2nd year Spring semester

506898

Dissertation
3rd year Fall semester

Non-credit
3(0-0-9)
Total credits 3
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9

506898

Dissertation
3rd year Spring semester

506898

Dissertation

9(0-0-27)
Total credits 9
Total 48 credits

Scheme 1.2
506591
506899

1st year Fall semester

Research Methods
Dissertation
1st year Spring semester

506899

Dissertation
2nd year Fall semester

506899

Dissertation
2nd year Spring semester

506899

Dissertation
3rd year Fall semester

506899

Dissertation
3rd year Spring semester

506899

Dissertation
4th year Fall semester

506899

Dissertation
4th year Spring semester

506899

9(0-0-27)
Total credits 9

Dissertation

Non-credit
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
9(0-0-27)
Total credits 9
Total 72 credits

Scheme 2.1
506591
506711
506xxx

1st year Fall semester

Research Methods
Advanced Topics in Biongineering
Elective Course I
1st year Spring semester

506xxx

Elective Course II

Non-credit
3(3-0-6)
3(3-0-6)
Total credits 6
3(3-0-6)

506xxx

Elective Course III


2nd year Fall semester

506998

Dissertation
2nd year Spring semester

506998

Dissertation
3rd year Fall semester

506998

Dissertation
3rd year Spring semester

506998

Dissertation

3(3-0-6)
Total credits 6
9(0-0-18)
Total credits 9
9(0-0-18)
Total credits 9
9(0-0-18)
Total credits 9
9(0-0-18)
Total credits 9
Total 48 credits

Scheme 2.2
506591
506511
506512
506513
506xxx
506xxx
506xx
506711
506999
506xxx
506999
506999
506999

1st year Fall semester


Non-credit
3(3-0-6)
3(3-0-6)
Bioeconomics and Entrepreneurship in Biotechnology
3(3-0-6)
Total credits 9
st
1 year Spring semester
Elective Course I
3(3-0-6)
Elective Course II
3(3-0-6)
Elective Course III
3(3-0-6)
Total credits 9
nd
2 year Fall semester
Advanced Topics in Bioengineering
3(3-0-6)
Dissertation
3(0-0-9)
Elective Course IV
3(3-0-6)
Total credits 9
nd
2 year Spring semester
Dissertation
9(0-0-18)
Total credits 9
rd
3 year Fall semester
Dissertation
9(0-0-18)
Total credits 9
rd
3 year Spring semester
Dissertation
9(0-0-18)
Total credits 9
th
4 year Fall semester

Research Methods
Bioengineering and Applications
System Bioengineering

506999

Dissertation
4th year Spring semester

506999

Dissertation

9(0-0-18)
Total credits 9
9(0-0-18)
Total credits 9
Total 72 credits

Course Description
Foundation courses
506401 Cell and Molecular Biology for Bioengineering
A general survey of structure-function relationships at the
molecular and cellular levels; basic genetic mechanisms;
control of gene expression; membrane structure; transport
and traffic; cell signaling; cell adhesion; mechanics of cell
division; and cytoskeleton

3(3-0-6)

506402

Physiology for Bioengineering


Introductory mammalian physiology for bioengineering
students; control mechanisms and bioengineering
principles. Basic cell functions; biological control systems;
muscle; neural; endocrine, and circulatory systems.
Digestive, respiratory, renal, and reproductive systems;
regulation of metabolism, and defense mechanisms

506403

Organic Chemistry and Biochemistry for Bioengineering


3(3-0-6)
Basic organic chemistry and biochemistry for
bioengineering; structures, functions and properties of
organic compounds and biological molecules; structure
and reactivity of organic molecules; type of reactions and
mechanism; structure-function relationships of biologically
important molecules in living cells; metabolisms

Compulsory courses
506591 Research Methods
Preparation for postgraduate research in bioengineering;
techniques for formulating, developing and completing a
research problem; evaluating and writing a research report;
development of a research proposal; ethnic; academic
presentation

3(3-0-6)

1(1-0-2)

Core courses
506511 Bioengineering and Applications
Molecular and cellular basis of life from an engineering
perspective; application of engineering principles, concepts,
and mathematical modeling in studying molecular parameters;
cell structure, function, and cellular phenomena; cell-function
relationship and cell-biomaterials relationship; explore and
criticize the existing and emerging technologies that exploit our
knowledge of molecular and cell biology
506512 System Bioengineering
Engineering analysis of biological systems from molecules to
organs; engineering approaches to the analysis of biological
systems including molecular and cellular techniques, signal
transduction and genetic circuits; cells and cardiovascular
systems, neural systems, genes to organs
506513 Bioeconomics and Entrepreneurship in Biotechnology
Development of new ventures including biotechnology-based
ventures; addressing opportunity identification and evaluation;
market assessment, startup strategies; business plan
development; venture financing and startup management
506711 Advanced Topics in Bioengineering
Advanced research topics or new development related to
bioengineering

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

Elective courses
Biomaterials Engineering
506621
Biomaterials Engineering
3(3-0-6)
Structure of solids; characterization of materials; metallic
implant materials; ceramic Implant materials; polymeric
implant materials; composites as biomaterials; structure
property relationships of biological materials; soft and hard
tissues; tissue response to implants; degradation of materials in
the biological environment
506622
Design and Applications of Biomaterials
3(3-0-6)
Biocompatibility and biological tests; soft tissue replacement;
dental materials and implants; mechanical properties of tooth
structures; design and applications of elbow prosthesis; design
and applications of shoulder prosthesis; knee joint

replacement; hip joint replacement; tissue-engineered scaffold


506623
Characterization of Biomaterials
Energy Dispersive X-ray spectroscopy (EDX); Wavelength
Dispersive X-ray spectroscopy (WDX); X-ray diffraction (XRD);
impulse excitation technique (IET); Auger electron
spectroscopy; X-ray photoelectron spectroscopy; Fourier
transform infrared spectroscopy (FTIR); mass spectrometry;
secondary ion mass spectrometry (SIMS); electron energy loss
spectroscopy (EELS); in vitro and in vivo tests; mechanical
properties of biomaterials; structure, elemental and chemical
compounds
506624
Polymeric Biomaterials
Biomedical implant and device applications of synthetic and
natural polymers; biocompatiblity and interfacial properties of
polymers in physiological environment; short-term devices
(catheters) and long-term implants (intraocular lenses, vascular
and mammary prostheses, etc.)
506625
Advanced Bioceramics
Structure of ceramics from synthesis to processing; Inert
bioceramics; bioactive ceramics; biodegradable ceramics;
biological glasses; biocomposite of ceramic/ceramic material;
applications of bioceramics; coating of bioceramics
506626
Advanced Surface Engineering
Nature of surface; surface roughness and measurement;
tribology (friction, wear and lubrication); surface treatments;
surface coatings; surface cleaning; surface analyzing
506628
Special Topics in Biomaterials Engineering I
Current interesting knowledge and technology in biomaterials
engineering
506629
Special Topics in Biomaterials Engineering II
Current interesting knowledge and technology in biomaterials
engineering and applications
Biomedical Engineering
506631
Modeling in Biomedical Engineering
Mathematical modeling of biomedical systems; lumped and
distributed models of electrical, mechanical, and chemical
processes applied to cells, tissues, and organ systems
506632
Biomedical Instrumentation

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)
3(3-0-6)

3(3-0-6)

3(3-0-6)

Physical, chemical and biological principles for biomedical


measurements; modular blocks and system integration; sensors
for displacement, force, pressure, flow, temperature,
biopotentials; chemical composition of body fluids and
biomaterial characterization; patient safety
506633
Metabolic System and Regulation
Mechanisms of metabolic control; recent research on a wide
range of specific metabolic systems is examined critically;
biochemical factors and principles for the integration and
control of metabolism
506634
Design of Medical Devices and Implants
Solution of clinical problems by use of implants and other
medical devices; systematic use of cell-matrix control volumes;
role of stress analysis in the design process; anatomic fit, shape
and size of implants; selection of biomaterials; instrumentation
for surgical implantation procedures; preclinical testing for
safety and efficacy, including risk/benefit ratio assessment
evaluation of clinical performance and design of clinical trials;
orthopedic devices; soft tissue implants; artificial organs and
dental implants
506635
Rehabilitation Engineering and Assistive Technology
Design and applications of rehabilitation engineering and
assistive technologies in a wide range of areas; wheeled
mobility; seating and positioning; environmental control;
computer access; augmentative communication; sensory aids;
emerging technologies
506638
Special Topics in Biomedical Engineering I
Current interesting knowledge and technology in bioengineering
506639
Special Topics in Biomedical Engineering II
Current interesting knowledge and technology in bioengineering
and applications
Bioprocess Engineering
506641
Biochemical Engineering
Biochemical engineering principles of the industrial microbial
and enzyme; kinetics of enzyme catalyzed reaction; utilization
of enzymes; metabolic pathways and energetic;
thermodynamics in biological processes; mass and energy
balance calculation for biological processes; kinetics of

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)
3(3-0-6)

3(3-0-6)

506642

506643

506644

506645

506646

506647

microbe-catalyzed reactions; transport phenomena in


biological processes; design and analysis of bioreactor;
economic analysis of biological processes
Bioseparation Engineering
Design, analysis and scale up of bioseparation processes;
purification and recovery of bioproducts, cell disruption,
centrifugation, precipitation, extraction, adsorption, membrane
separation, chromatography, crystallization
Metabolic Engineering
Metabolism; construction and analysis of metabolic networks;
design and customization of metabolism; metabolic flux
analysis; metabolic control analysis; transcriptional regulation
and signal transduction; applications of metabolic engineering
to improve the living species in biotechnology and agriculture
Biological System Modeling and Controls
Analysis and development of mathematical modeling in
chemical and biological processes including steady and
unsteady state condition; control of chemical and biological
processes; case studies of modeling and control in biological
industries
Biotransport Phenomena
Systematic development of the concepts and equations for
momentum, heat and mass transfer to solve transport
problems in biological process engineering; transport concepts
in the development of artificial organs and controlled drug
delivery systems
Biological Reaction Engineering and Bioreactor Design
Development of mathematical modelling of biological
reactions and bioreactors; design and analysis of bioreactors;
dynamics of bioreactors; controls; selection and scale up of
bioreactors; economic analysis of bioreactor design
Enzymatic Engineering
General properties of enzymes; kinetics and enzymatic stability;
enzyme immobilization and immobilized enzyme kinetics;
design and analysis of enzymatic reactors; biocatalysis in nonconventional systems; applications of enzymatic technologies
to biosensors, enzymatic clinical diagnosis, and industrial
processes

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

506648

Special Topics in Bioprocess Engineering I


Current interesting knowledge and technology in bioengineering
506649
Special Topics in Bioprocess Engineering II
Current interesting knowledge and technology in bioengineering
and applications
Bioelectronics, Bioimaging and Bioinformatics
506651
Advanced Mathematics for Bioengineering
Applications of advanced mathematical techniques to solve
bioengineering problems; mathematical techniques include
ordinary differential equation, partial differential equation,
numerical methods and advanced mathematical methods
506652
Algorithms for Functional Genomics
Analysis of DNA, RNA and protein sequences; sequence
alignment; genomics databases; gene expression; microarray
data analysis; functional genomics; genome analysis
506653
Computational Biology and Bioinformatics
Strings processing and application to biological sequences;
algorithms for problems in computational biology; analysis of
biological sequences; motif finding and structure prediction;
microarray data analysis; analysis of genomes; analysis of
biological networks
506654
Machine Learning
Decision tree; probabilistic methods; Bayes classifiers;
maximum likelihood estimation; Gaussian Bayes classifiers;
regression; neural networks; cross-validation; PAC learning; VCdimension; support vector machines; k-nearest neighbor;
Bayesian networks; k-means
506655
Signals and Systems
Signal processing, sinusoidal waveform, signal properties;
frequency transformations; Fourier series analysis; Fourier
transform; circuit and sinusoidal analysis; Laplace transform;
transfer function; system model and behavior
506656
Statistical Signal Processing in Biomedical Engineering
Characterization of signals and linear time-invariant systems;
conversion of continuous-time signals to discrete-time signals;
modeling of stochastic signals from white noise; energy and
power signals; principles of autocorrelation for discrete-time
signals; linear prediction and optimum linear filtering; least-

3(3-0-6)
3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

squares methods for system modeling and filtering design


506657
Digital Image Processing
Image perception; image digitization; image enhancement;
image restoration; image segmentation; image compression;
morphological image processing; image representation and
description
506658
Special Topics in Bioelectronics, Bioimaging and Bioinformatics I
Current interesting knowledge and technology in bioengineering
506659
Special Topics in Bioelectronics, Bioimaging and Bioinformatics II
Current interesting knowledge and technology in bioengineering
and applications
Biopharmaceutical Engineering
506661
Pharmaceutical Process Design
Synthesis, separation, and sterile processing; applications to
designing and optimizing pharmaceutical processes; drug
synthesis in industrial pharmaceutical; separation; distillation;
crystallization; filtration; lyophilization; drying processes
506662
Pharmaceutical Kinetics, Thermodynamics and Transport
Processes
Concepts of transport phenomena, thermodynamics, and
reaction engineering, basic physiology; fundamentals of drug
delivery: kinetics of drug absorption, distribution, and
elimination; fundamental issues relevant to the design of drug
products having immediate release, delayed release, sustained
release and extended release profiles; generation and fate of
metabolites
506663
Pharmaceutical Materials and Pharmaceutical Organic
Nanotechnology
Pharmaceutical materials engineering; designing and optimizing
pharmaceutical processes and products; production,
characterization and usage of pharmaceutical materials;
introduction to organic nanotechnology; application to
manufacturing drug products
506664
Nanotechnology-based Drug Design and Delivery
Identifying new drug leads, drug absorption and distribution;
pharmacomodulation, enzymes and receptors as targets;
computer-aided drug design and combinatorial chemistry; drug
delivery; materials and processes for novel drug delivery

3(3-0-6)

3(3-0-6)
3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

systems; synthesis of biocompatible nano-particles for


healthcare; product design; regulatory issues
506665
Structure and Function of Drugs
Survey of the major pharmaceutical agents in clinical use.;
influence of chemical structure in the elicitation of
pharmacological effects
506666
Chemical Tools for Assessing Biological Function
Contemporary bioorganic chemistry and chemical biology;
applications of chemical approaches to interrogate biochemical
function including specific enzyme inhibition as a mechanism
for rational drug design; molecular mechanisms of drug
resistance; uses of intrinsic and extrinsic reporter functionality
to understand biological functions and interactions; chemical
methods for probing cellular activities in real time
506668
Special Topics in Biopharmaceutical Engineering I
Current interesting knowledge and technology in
biopharmaceutical engineering
506669
Special Topics in Biopharmaceutical Engineering II
Current interesting knowledge and technology in
biopharmaceutical engineering and applications
Stem Cell and Biomolecular Engineering
506671
Molecular and Genetic Engineering
Cellular processes in the cytoplasm, cell, organellar
membranes and nucleus; uses of recombinant DNA
technology in investigating gene structure and function and in
diagnosing genetic diseases complement examination of
inheritance patterns in humans; review of genetic loci that
underlie human disease
506672
Protein Engineering
Principles of modern molecular and cellular biology for
engineers and other non-life-scientists; genes; protein structure
and function; organization of cells and cellular trafficking
506673
Cell and Protein Interaction
Interaction between cell-cell, cell-protein and protein-protein;
system biology and signal transduction; current technology for
biomolecular biding assay
506674
Tissue Engineering and Stem Cell Processing
Overview of molecular biology; extensive review on

3(3-0-6)

3(3-0-6)

3(3-0-6)
3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

3(3-0-6)

extracellular matrix and basics of receptors, cell-cell and cellmatrix interactions at both the theoretical and experimental
levels; effects of physical, chemical and electrical stimuli on
cell function; gene regulation and signal transduction
processes; material on cell-cycle; apoptosis; metabolic
engineering and gene therapy
506675
Tissue, Cellular and Molecular Basis of Disease
Regulation of gene expression at the interface of chemistry,
biology and genomics; molecular mechanism responsible for
disease; programmed cell death (apoptosis); proteolytic
processing; gene expression; morphological study of tissue and
cell disorder
506676
Stem Cells in Organogenesis, Carcinogenesis and Atherogenesis
Origins of human clonal diseases using cytologic, genetic and
mathematical observations incorporated in computer cascade
models; introduction to metakaryotic stem cell biology;
application to the analysis of age-specific disease mortality
data including basic population genetics of inherited risk factors
506678
Special Topics in Stem Cell and Biomolecular Engineering I
Current interesting knowledge and technology in Stem Cell and
Bimolecular Engineering
506679
Special Topics in Stem Cell and Biomolecular Engineering II
Current interesting knowledge and technology in Stem Cell and
Bimolecular Engineering and applications
Thesis and Dissertation
506697
Thesis
Purpose of research; literature reviews, analysis and synthesis;
confidence evaluation of reviewed literature; research aims and
objectives; research methodologies; research proposals;
research conducts; result processing and analysis; result
synthesis; discussions; citations and international bibliographic
systems; full research report compilation; research article
authoring; abstract presentation; oral presentations; ethics and
code of conducts of researchers; ethics in publishing academic
works
506699

3(3-0-6)

3(3-0-6)

3(3-0-6)
3(3-0-6)

36(0-0-108)

Thesis
12(0-0-36)
Purpose of research; literature reviews, analysis and synthesis;
confidence evaluation of reviewed literature; research aims and

objectives; research methodologies; research proposals;


research conducts; result processing and analysis; result
synthesis; discussions; citations and international bibliographic
systems; full research report compilation; research article
authoring; abstract presentation; oral presentations; ethics and
code of conducts of researchers; ethics in publishing academic
works
506898

Dissertation
48(0-0-144)
Purpose of research; literature reviews, analysis and synthesis;
confidence evaluation of reviewed literature; research aims and
objectives; research methodologies; research proposals;
research conducts; result processing and analysis; result
synthesis; discussions; citations and international bibliographic
systems; full research report compilation; research article
authoring; abstract presentation; oral presentations; ethics and
code of conducts of researchers; ethics in publishing academic
works

506899

Dissertation
72(0-0-216)
Purpose of research; literature reviews, analysis and synthesis;
confidence evaluation of reviewed literature; research aims and
objectives; research methodologies; research proposals;
research conducts; result processing and analysis; result
synthesis; discussions; citations and international bibliographic
systems; full research report compilation; research article
authoring; abstract presentation; oral presentations; ethics and
code of conducts of researchers; ethics in publishing academic
works

506998

Dissertation
36(0-0-108)
Purpose of research; literature reviews, analysis and synthesis;
confidence evaluation of reviewed literature; research aims and
objectives; research methodologies; research proposals;
research conducts; result processing and analysis; result
synthesis; discussions; citations and international bibliographic
systems; full research report compilation; research article
authoring; abstract presentation; oral presentations; ethics and
code of conducts of researchers; ethics in publishing academic
works

506999

Dissertation
48(0-0-144)
Purpose of research; literature reviews, analysis and synthesis;
confidence evaluation of reviewed literature; research aims and
objectives; research methodologies; research proposals;
research conducts; result processing and analysis; result
synthesis; discussions; citations and international bibliographic
systems; full research report compilation; research article
authoring; abstract presentation; oral presentations; ethics and
code of conducts of researchers; ethics in publishing academic
works

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