DRUG STUDY

DRUG ORDER
(Generic name, Brand
name, classification,
dosage, route, frequency)
GENERIC NAME:
lidocaine hydrochloride
,lidocaine HCl in 5%
dextrose , lidocaine HCl
without preservatives
BRAND NAME:
(Parenteral) LidoPen,
Xylocaine (Local
Anesthetic) Dilocane,
Lidoject, Nervocaine,
Octocaine, Xylovaine
(Mucosal) Anestacon,
Xylocaine Viscous
(Lidocaine Patch)
Lidoderm, (Topical)
DermaFlex, ELA-Max,
Solarcaine, Aloe Extra
Burn Relief, Xylocaine,
Zilactin-L
CLASSIFICATION:
Anesthetic topical or
local, Antiarrythmics

MECHANISM OF ACTION
When administered
intramuscularly or intravenously,
Lidocaine suppresses the
automaticity and spontaneous
depolarization of the ventricles
during diastole by altering the
flux of sodium ions across the
cell membrane with little or no
effect on the heart. Locally, it
produces local anesthesia effect
by inhibiting the transport of ions
across the neural membranes.
Thus, initiation and conduction of
normal nerve impulses is
prevented.

INDICATIONS

Intravenous
ventricular arrhythmias
Intramuscular selfinjected or when IV is
unavailable during
transport to local facilities
Local infiltration or
mucosal or topical
anesthetic
Patch used when
pain is present due to
post-herpetic neuralgia

CONTRAINDICATIONS

Hypersensitivity
Advanced AV block

ADVERSE EFFECTS OF THE

DRUG
Adverse reactions

Drowsiness

Dizziness

Nervousness

(mucosal use) decreased

or absent gag reflex

Bradycardia

Hypotension

Burning sensation

NURSING RESPONSIBILITIES/
PRECAUTIONS

When Lidocaine is
administered as an
antiarrhythmic the nurse should
monitor the ECG continuously.
Blood pressure and respiratory
status should be monitored
frequently during the drug
administration.
When administered as an
anesthetic, the numbness of the
affected part should be assessed.
Serum Lidocaine levels
should be monitored frequently
during prolonged
use. Therapeutic serum
lidocaine levels range from 1.5
to 5 mcg/ml.
If signs of overdose occur,
stop the infusion immediately and
monitor thepatient closely.