Beruflich Dokumente
Kultur Dokumente
Cataract can present with diffusely compromised zon- visual acuity (CDVA) is limited or threatened by irreg-
ular fibers, as is commonly found in Weill-Marchesani ular lenticular astigmatism, cataract change, or angle-
syndrome, pseudoexfoliation syndrome, and homo- closure glaucoma.
cystinuria. Focal zonular loss commonly occurs as a In patients with extensive zonular weakness, endo-
result of ectopia lentis, Marfan syndrome, sulfate capsular support devices such as sutured modified
oxidase deficiency, and trauma. Cataract surgery capsular tension rings (CTRs) or the Ahmed capsular
with intraocular lens (IOL) implantation in eyes with tension segment (CTS) are helpful in promoting long-
diffuse zonular loss presents a greater surgical chal- term stability of the IOLcapsule system.2,3 Capsular
lenge than in eyes with focal zonular loss; however, tension rings are widely used to compensate for
in both instances, patients should be made aware of limited zonular defects during cataract extraction
the higher associated rates of complications.1 Surgery and can help prevent eccentric capsule contraction
is most often offered when the corrected distance with subsequent IOL decentration.4 For zonular loss
Figure 1. Preoperative view of subluxated cataractous lens due to Figure 2. Intraoperative view of sutured ring segment with aligned
zonular compromise. toric IOL.
greater than 4 clock hours, scleral suture fixation of a placement of a sutured ring or Ahmed segment in combina-
CTS or sutured CTR is often warranted to promote tion with a toric IOL (all IOLs, Alcon Laboratory, Inc.)
capsule centration and stability. These scleral-sutured between 2010 and 2014 were included in the study.
Preoperative data collected included CDVA, manifest
elements might lead to potential complications, refraction, cylindrical power, keratometry values, and
including erosions over the sutures, induced astigma- degree of zonular defect. Figure 1 shows a preoperative
tism, and delayed IOL subluxation from broken view of a subluxated cataractous lens due to zonular
sutures.5 compromise. Automated and manual keratometry measure-
Toric IOLs have been shown to safely and effectively ments were taken, and biometry was performed to deter-
mine the appropriate IOL spherical power to achieve the
reduce or neutralize corneal astigmatism in appropri- patient's selected refractive target. Cylindrical power and
ately selected patients having cataract extraction.6 axis placement were calculated using the Alcon toric intraoc-
These IOLs might be considered an option for patients ular lens calculator.A Postoperative data included CDVA at
with evidence of zonular compromise. Here we report each follow-up visit, postoperative enhancement proce-
our experience with combined placement of toric IOLs dures, postoperative refraction, and outcomes. One of 2
surgeons (H.A.H., R.J.C.) performed all surgeries.
with a modified CTR and/or CTS scleral fixation Because these cases tend to be challenging, the surgical
device in eyes with diffuse or focal zonular compro- technique might have varied somewhat from patient to
mise requiring cataract surgery. patient and between the 2 surgeons. Video 1 (available at
http://jcrsjournal.org) exemplifies the typical case, which
consisted of a 2.4 mm clear corneal incision with 1 or
PATIENTS AND METHODS more paracenteses followed by creation of a continuous
This retrospective observational study was performed in curvilinear capsulorhexis whereupon hydrodissection and
accordance with the Declaration of Helsinki, and the study viscodissection were used to free the nucleus. The cataract
protocol was approved by the Institutional Review Board, nucleus was extracted using a quick-chop phacoemulsifica-
Kaiser, Santa Clara Hospital, Santa Clara, California. All tion or a divide-and-conquer technique assisted by the use
patients of any age with lens subluxation or phacodonesis of capsular support hooks as necessary. The cortical material
from any etiology who had cataract extraction requiring was then removed with a combination of an irrigation/
aspiration (I/A) handpiece and a bimanual I/A unit. An
appropriately sized CTR was then placed in the capsular
bag for circumferential zonular support followed by a CTS
that was placed in the area of greatest zonular weakness
Submitted: August 13, 2015. and sutured to the sclera 2.0 mm posterior to the limbus
Final revision submitted: September 30, 2015. using a 9-0 polypropylene (Prolene) or a 8-0 polytetrafluoro-
Accepted: October 4, 2015. ethylene (Gore-Tex) suture through a Hoffmann et al.
pocket.7 The toric IOL was implanted and aligned with the
From the School of Medicine (Do), Stanford University, Palo Alto, intended axis to best achieve astigmatism neutralization.
and Kaiser Permanente (Holz), Santa Clara, California; the Eye The ophthalmic viscosurgical device (OVD) was then
Institute of Utah (Cionni), Salt Lake City, Utah, USA. removed with I/A, and the wounds were sealed with
stromal hydration and sutured when necessary.
Corresponding author: Huck A. Holz, MD, Kaiser Permanente The surgical technique for patients requiring a sutured
Santa Clara, Ophthalmology Department, Suite 490, 710 Lawrence modified CTR consisted of a similar procedure except that
Expressway, Santa Clara, California 95051, USA. E-mail: huck. after the cortex was removed, a sutured Cionni ring was
holz@kp.org. fixated to the sclera with a 9-0 polypropylene or an 8-0
Preoperative
CDVA 20/402 CF 30 20/200
LogMAR CDVA 0.301 1.301 1
Manifest refraction 5.75 C2.25 45 13.75 C4.75 70 3.00 C1.50 180
Astigmatism 2.25 4.75 1.50
Manual steep K (D@o) 42.20@77 43.23@11 42.01@61
Manual flat K (D@o) 40.22@16 40.86@21 40.78@15
Corneal astigmatism (D) 1.99 2.36 1.24
Comorbidities Diabetes without retinopathy Marfan syndrome Marfan syndrome
AMD Z age-related macular degeneration; CDVA Z corrected distance visual acuity; CF Z counting fingers; CTR Z capsular tension ring; FU Z follow-up;
IOL Z intraocular lens; Nd:YAG Z neodymium:YAG laser capsulotomy; PCO Z posterior capsule opacification; PRK Z photorefractive keratectomy;
UDVA Z uncorrected distance visual acuity
polytetrafluoroethylene suture. The toric IOL was then calculator.A The OVD was then removed with I/A, and the
implanted and aligned with the steep axis of astigmatism wounds were sealed. Figure 2 shows an intraoperative
according to the calculations done by the Alcon toric IOL view of a sutured Ahmed CTS aligned with toric IOL.
Table 1. (Cont.)
No No No No No
PRK d d d d
20/401 d 20/202 d d
20/30 20/30 20/20 20/50 20/40
20/80 20/60C2 20/15
20/301 20/201 20/30 20/40
20/40 d 20/15
d d d 20/40C2 20/50C2
d d d d d
d d d 20/25C1 20/60C2
20/40 20/60C2 20/15 d
0.301 0.462 0.125
20/30 20/201 20/15 20/25C1 20/60C2
0.176 0.019 0.125 0.116 0.42
Plano C0.75 135 1.50 C0.50 120 Plano 0.50 C2.75 83 1.25 C4.25 96
0.75 0.51 0.00 2.75 4.25
26 3 6 50 50
None None None None None
The CDVA was measured on the Snellen chart and preoperatively was analyzed using the 2-tailed Student
converted to logMAR values for statistical analysis. The t test. A P value less than 0.05 was considered statistically
change in mean the CDVA postoperatively compared with significant.
CDVA Z corrected distance visual acuity; UDVA Z uncorrected distance visual acuity
*Excluding patients 7, 9, and 10
Excluding patients 3, 4, 6, 7, 9, and 10
11. Kandar AK. Combined special capsular tension ring and toric 15. Vasavada V, Vasavada VA, Hoffman RO, Spencer TS,
IOL implantation for management of post-DALK high regular Kumar RV, Crandall AS. Intraoperative performance and post-
astigmatism with subluxated traumatic cataract. Indian J operative outcomes of endocapsular ring implantation in pediat-
Ophthalmol 2014; 62:819822. Available at: http://www.ncbi. ric eyes. J Cataract Refract Surg 2008; 34:14991508
nlm.nih.gov/pmc/articles/PMC4152657/?reportZprintable. Ac-
cessed December 10, 2015 OTHER CITED MATERIAL
12. Gimbel HV, Camoriano GD, Aman-Ullah M. Bilateral implanta- A. Alcon Surgical, Inc. AcrySof Toric IOL Web Based Calculators.
tion of scleral-fixated Cionni endocapsular rings and toric intra- Available at: http://www.acrysoftoriccalculator.com. Accessed
ocular lenses in a pediatric patient with Marfans syndrome. December 12, 2015
Case Rep Ophthalmol 2012; 3:1623. Available at: http://www.
ncbi.nlm.nih.gov/pmc/articles/PMC3357140/pdf/cop-0003-0016.
pdf. Accessed December 10, 2015
First author:
13. Kim W-S. Transscleral intraocular lens fixation with preser-
Anna T. Do, MD
vation of the anterior vitreous face in patients with Marfan
syndrome and ectopia lentis. Cornea 2010; 29(suppl 1): From the School of Medicine,
S20S24 Stanford University, Palo Alto,
14. Konradsen T, Kugelberg M, Zetterstro m C. Visual outcomes and
California, USA
complications in surgery for ectopia lentis in children. J Cataract
Refract Surg 2007; 33:819824