1. An drug from a plant source ?

paclitaxel
2. Copays are used by third parties to ? utilization
3. An antagonist ? has affinity but no effect
4. An antagonist that increase km but vmax no change ? competitive antagonist
5. Jugular vein distention and peripheral edema ? heart failure
6. alginic acid ? increase viscosity
7. can cause hemorrhage ? rat poison
8. the most variable drug administration route ?
9. tuberculin route ? intradermal
10. all can cause hyperkalemia except ? nitrate
11. in airborne isolation use ? n95 mask
12. pregnancy clinical study for 3 wks what is the weakness ? duration
13. an open label rct for 3 years and 1200 people what is the weakness ? blindness
14. double-dummy technique may be used for ? blinding
15. calculate relative auc = ( auc drug / auc compared to )
* ( dose compared / dose drug )
16. drug body conc . day 1 90 day 2 85 day 3 80 day 4 75 ? zero order
17. in first order , drug rate of elimination is proportional to ? drug conc.
18. making the patient take a drug opposing his opinion called ? paternalism
19. should not be given with antacids ? moxifloxacin ( and all flouroquinolone )
20. minimum ca requirements ? > 1200 or > 1500 / day
21. when blood release o2 on increased or decreased ph ?
22. the functional group in tigecycline that makes it broad ? ( structure )
23. phemyl alanine structure ? missing group x ? carboxyl group

24. the substance that is least likely to be detected in a 24 h urine drugs test ?
amphetamine .. ( amphetamine is basic trapped in acidic urine )
25. what happens in asthma patients ? increase lung capacity and volume but
decrease fev why ? not able to exhale enough
26. what is the interxn between digoxin and amiodarone ?
27. smoking induce cyp 1A2 when taking a drug that is a cyp 1A2 THEN QUIT
SMOKING what will happen ? drug cl will decrease and drug conc will
increase.
28. when non cooked food that contain thiamines are consumed much ?
berryberry
29. on what mechanism does ethanol antagonize polyethylene glycol or methanol
toxicity ? by competing on alcohol dehydrogenase thus decreasing toxic
metabolite .
30. when the drug is still in its patent ( 20 years ) and no other drug is allowed in
the market with the same chemical ingredient ? pure monopoly
31. according to fda what is room temp ? 20 c
32. what factor is not included in guidelines for products packaging rules ? temp
when delivered .
33. what is the metal that catalyse the activity of ACE ? Zn
34. the liver has a large amounts of what vitamin ? vitamin a , retinol
35. what type of ginseng doesnt produce ginsenoids ? Siberian ginseng .
36. a diabetic man on insulin is planning to start a religious 1 month fasting ? what
do you recommend for his glucose control ? decrease morning dose and
monitor frequently .
37. the disease where is no autoimmunity factor is ? type 2 DM .
38. two mirrot images molecules ? ( not superimposable ? ) enantiomers . to
similar molecules , not mirror images differ in only one substitute ?
isosterism .
39. the process of removing water from products by freezing then sublimation ?
lyophilization.
40. non sterile products that contain water should be used for ?
41. a hypertensive whith HF and diabetis , went to the pharmacy complaining
congestion and want to choose a decongestant . what factor is the most
important ? ( HTN .. phenylphrine increase blood pressure ) .
42. ascorbic acid in production is used as as ? antioxidant
43. algininc acid is used as ? increase viscosity
44. structure of tolbutamide then a patient has allergy of it then 4 structures and
ask which of them he should not take ?
45. structure of a thiazide asking what main side effect ? ( the structure contain S )
.. PHOTOSENSETIVITY .
46. why it is so hard to make anti HIV drugs ?

47.
what is x ? alcohol dehydrogenase

48. a drug that is an derived from a prostaglandin mesoprostol

49. a drug that work by decreasing fat absorption from GUT ? orlistat
50. how many kcal from 50 ml from 5% dextrose solution ?
51. human subjects participating in clinical research are consistent with the
ethical principles put forth in the ? Declaration of Helsinki.