EUROPEAN

RESUSCITATION
COUNCIL
Anaphylaxis
Anaphylactic reaction?

Assess using ABCDE approach

Diagnosis - look for:

n Acute onset of illness
n Life-threatening Airway and/or
Breathing and/or Circulation problems1

n And usually skin changes

n Call for help

n Lie patient flat with raised legs (if breathing allows)

Adrenaline 2

When skills and equipment available:

n E stablish airway Monitor:
n High flow oxygen n P
 ulse oximetry
n I V fluid challenge 3 n E
 CG
n C hlorphenamine 4 n B
 lood pressure
n H ydrocortisone 5

Life-threatening problems:
1.

Airway: swelling, hoarseness, stridor

Breathing: rapid breathing, wheeze, fatigue, cyanosis, SpO2 < 92%, confusion
Circulation: p
 ale, clammy, low blood pressure, faintness, drowsy/coma

Adrenaline (give IM unless experienced with IV adrenaline)

2.
IV fluid challenge (crystalloid):
3.

IM doses of 1:1000 adrenaline (repeat after 5 min if no better) Adult 500 - 1000 mL
n Adult 500 mcg IM (0.5 mL) Child 20 mL kg-1
n Child more than 12 years 500 mcg IM (0.5 mL)
n Child 6-12 years 300 mcg IM (0.3 mL) Stop IV colloid if this might be the cause
n Child less than 6 years 150 mcg IM (0.15 mL)
of anaphylaxis
Adrenaline IV to be given only by experienced specialists
Titrate: Adults 50 mcg; Children 1 mcg kg-1

4.
Chlorphenamine 5.
Hydrocortisone
(IM or slow IV) (IM or slow IV)
Adult or child more than 12 years 10 mg 200 mg
Child 6 - 12 years 5 mg 100 mg
Child 6 months to 6 years 2.5 mg 50 mg
Child less than 6 months 250 mcg kg-1 25 mg

www.erc.edu | info@erc.edu
Published October 2015 by European Resuscitation Council vzw, Emile Vanderveldelaan 35, 2845 Niel, Belgium
Copyright: European Resuscitation Council vzw - Reproduced with permission from Elsevier Ireland Ltd.- license number 3674081014315
Product reference: Poster_SpecCircs_Anaphylaxis_ENG_20150930