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CHAPTER

David H. Kim

131 Jeffrey A. Rihn


Todd J. Albert

Anterior and Posterior


Instrumentation Techniques
Used in the Thoracic Spine for
Treatment of Fractures

INTRODUCTION systems available. Formal discussion of technical differences


among specific implant systems will not be attempted. Rather,
There exists relatively little trauma-specific clinical outcomes this chapter will focus on general principles of thoracic pedicle
data to support formulation of guidelines with respect to surgi- screw (TPS) instrumentation, the use of interbody cages in the
cal instrumentation of the unstable thoracic spine. Most surgi- thoracic region, and anterior vertebral body screw fixation that
cal instrumentation principles and techniques for the thoracic are commonly shared by all systems.
spine borrow heavily from scoliosis studies. The degree to
which such principles can reasonably be transferred to acute
traumatic situations remains unclear. THORACIC PEDICLE SCREWS
This chapter will discuss the most commonly utilized and
widely accepted surgical instrumentation techniques for stabi- Use of TPS implants for spinal stabilization provides several
lizing the thoracic spine following acute or subacute trauma. advantages over other posterior instrumentation options. Com-
Such principles will be presented in the setting of relevant pared with segmental hook and wire fixation, pedicle screws pro-
reported studies or consensus expert opinion. Full discussion vide significantly greater fixation strength; therefore, comparable
regarding preoperative evaluation and surgical indications is stability may be achieved through fusion and instrumentation of
included in the chapter addressing trauma classification. fewer levels. Torsional strength of long thoracic constructs is
Similarly, detailed discussion of decompression techniques, superior to segmental hook constructs even with the addition of
perioperative complication management, and thoracolumbar cross-links.35 Secondly, avoidance of implant placement within
junction injuries is included in other chapters. the spinal canal, such as that occurs with laminar hooks or wires,
may reduce the risk of iatrogenic neurological injury.27 Finally,
pedicle screws can be placed at levels with laminar fractures or
USE OF INSTRUMENTATION IN where laminectomies have been performed.
THORACIC SPINAL TRAUMA Although initial concerns regarding the potential for seri-
ous injury to the spinal cord and pleural and vascular tissue
Early surgery for acute thoracic spinal trauma is generally per- slowed widespread adoption of this technique, clinical studies
formed for purposes of spinal canal/cord decompression in have suggested that rates of neurological injury as well as vis-
the setting of an incomplete neurological injury and/or to pro- ceral organ and vascular injury are very low.
vide immediate stabilization of three-column injuries. Immedi-
ate stability is provided by use of instrumentation that restores
RELEVANT ANATOMY
and maintains spinal alignment. Three instrumentation options
are in common use: posterior segmental hook and screw fixa- There have been several anatomic studies reporting pedicle
tion systems, anterior interbody cages, and anterior plate/rod dimensions in the thoracic spine (Table 131.1).2,6,18,26,29,37
fixation with vertebral body screws. Detailed techniques for Despite small differences in reported mean pedicle diameters
applying thoracic laminar, pedicle, and transverse process among studies, Panjabi et al26 have suggested the concept of
hooks can be found in the chapter discussing surgical treat- three distinct anatomic zones within the thoracic spine. The
ment of scoliosis. proximal zone consists of the T1 through T4 vertebrae and rep-
Since publication of the previous edition of this textbook, resents a transition zone from cervical to thoracic vertebral
there has been exponential growth in the number of implant morphology. The middle thoracic zone includes the T4 through
1411

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1412 Section XII Trauma

TABLE 131.1 Measurements of the Thoracic Vertebrae*

Parameter T4 T5 T6 T7 T8 T9 T10 T11 T12


Chord length of 44.1  8.2 39.3  3.8 38.9  5.4 43.6  3.5 44.7  3.1 43.5  5.0 44.1  5.1 40.8  5.8 46.6  5.2
pedicle (n = 12) (n = 12) (n = 8) (n = 16) (n = 18) (n = 24) (n = 22) (n = 20) (n = 12)
(mm)
Transverse diameter of 4.5  61.2 4.4  1.1 4.6  1.1 4.9  1.1 5.1  1.2 5.8  1.5 6.7  1.6 8.0  1.9 7.8  2.0
pedicle (mm)
Angle of insertion of 13.9  3.6 12.6  3.7 8.6  3.6 7.4  3.8 6.9  5.0 7.1  4.6 4.1  6.1 0.7  3.3 0.3  2.7
pedicle (degrees)
Length of pedicle (mm) 16.1  3.0 16.7  2.9 17.0  3.3 17.5  2.9 18.3  3.4 19.1  3.5 17.9  3.4 17.9  3.6 18.8  4.1
Height of pedicle (mm) 10.1  1.5 10.0  1.6 10.1  1.4 10.8  1.4 11.1  1.4 12.3  1.6 14.1  1.4 15.0  1.5 14.7  1.4
Length or width of 18.8  2.9 20.5  2.9 21.5  3.2 23.3  3.3 23.5  2.9 24.2  2.7 24.8  3.1 25.3  3.6 26.3  2.6
vertebral body (mm)
Distance from spinous 7.3  1.5 7.1  1.4 7.3  0.9 7.2  1.0 7.3  1.1 7.5  1.0 7.5  0.9 7.8  1.2 8.9  1.3
process to medial
wall of pedicle (mm)
Distance from spinous 12.5  1.7 12.4  1.8 12.8  1.7 12.8  1.7 13.0  1.7 13.7  2.0 14.7  2.6 16.1  2.7 17.4  3.4
process to lateral
wall of pedicle (mm)
Distance from margin 13.7  1.7 14.0  1.5 14.5  1.3 15.1  1.4 14.9  0.9 15.3  1.6 16.4  0.2 17.4  2.3 19.5  1.7
of inferior facet to
outer wall of
pedicle (mm)
*
The values are given as the mean and standard deviation.

Thirty-four measurements were performed for each parameter except chord length; for that parameter, the number of pedicles that were
measured is given in parentheses for each vertebral level.
Reprinted with permission from Vaccaro AR, Rizzolo SJ, Allardyce TJ, et al. Placenent of pedicle screws in the thoracic spine. Part I:
morphometric analysis of the thoracic vertebrae. J Bone Joint Surg Am 1995;77(8):1195, Table 1.

T10 vertebrae. The distal zone is composed of the T10 through represents 61.3% to 71.6% of the pedicle width. The cancellous
T12 vertebrae and represents a transition between thoracic and bone content of the thoracic pedicle does not affect bending
lumbar morphology. characteristics but does have a significant effect on pullout
Narrowness of the thoracic pedicles compared with those in strength. The medial pedicle wall is two to three times thicker
the lumbar region represents the major challenge for placement than the lateral wall at all levels.
of pedicle screws. Mean pedicle width at T1 is 8.4 mm and
decreases to a mean of 6.3 mm at T3-T8 then increases approxi-
BIOMECHANICAL PRINCIPLES
mately 0.7 mm/level to T12 where the mean pedicle width is
8.7 mm.26 Conceptualizing the thoracic pedicle as an oval in Pedicle screw instrumentation of the lumbar spine is generally
cross-section facilitates discussion, but in reality, the true cross- considered to provide superior fixation strength compared
sectional profile of the thoracic pedicle is more typically kidney- with laminar hooks and wires. Although screw fixation has been
or teardrop-shaped with a convex medial border and concave reported to provide superior deformity correction compared
lateral border. This irregular shape further decreases the effective with hooks and wires when utilized in the thoracic spine, bio-
transverse pedicle diameter with respect to screw placement. mechanical studies have provided conflicting data. When
Although nerve root injury is possible with inferiorly malpo- reviewing this data, it is critical to consider study design. Screw
sitioned screws, the rate of such complications appears rela- diameter and length strongly affect performance as does inser-
tively uncommon. The cross-sectional height of the thoracic tion technique, loading parameters, and specimen quality.
pedicles is disproportionately large and ranges from a mean of In the setting of weaker osteoporotic bone, paired hooks in
9.6 mm at T1 through a mean of 11.9 mm at T3-T9 to a mean a claw configuration may provide superior fixation. This is not
of 16.6 mm at T12.26 As a result, pedicle height is not a limiting surprising given the implantbone contact relations of pedicle
factor in terms of screw placement. screws compared with hooks. With standard intrapedicular
Pedicle axis angulation with respect to the sagittal and trans- placement of screws, threads largely engage cancellous bone,
verse planes is fairly symmetric. Relative to the sagittal plane, while the contact area of hooks involves mostly cortical bone,
the pedicle demonstrates a mean angle of 27 at T1-T2 and which is much less affected by osteoporosis.
progressively decreases to 10 at T12.26 The transverse plane
inclination demonstrates a mean of approximately 9 at T3-11
but jumps from 7.6 at T1 to 17.9 at T2 and from 8.7 at T11 to
SURGICAL TECHNIQUE
5.0 at T12. Significant variation in sagittal plane orientation
occurs in the midthoracic region further increasing the diffi-
STARTING POINT
culty of pedicle screw placement.
Histologically, cross-sectional examination of the thoracic Selecting an appropriate starting point for pilot hole prepara-
pedicles has revealed that cancellous bone predominates and tion is critical for minimizing the risk of implant malposition.

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Chapter 131 Anterior and Posterior Instrumentation Techniques Used in the Thoracic Spine for Treatment of Fractures 1413

middle of the superior facet. A comparison of starting point


SF selection based solely on local anatomic landmarks was made
comparing the intersection of the superior border of the trans-
verse process and the middle of the superior facet versus the
P intersection of the superior border of the transverse process
and the external one third of the superior facet. The latter
starting point was found to result in fewer pedicle violations
and anterior cortical penetrations. The same study also reported
less variability in the sagittal location of the pedicle axis with
respect to the superior border of the transverse process com-
pared with the superior facet, supporting use of the transverse
process as an anatomic landmark. Despite these findings, sig-
TP nificant variation in pedicle location relative to both the trans-
verse process and superior facet was found. Of note, the small-
est average pedicle diameter was found at T6 (4.3 mm) followed
by T7 (4.7 mm), T8 (4.8 mm), and T5 (4.9 mm). The authors
suggested that T4 through T8 pedicles may be too small for
intrapedicular screw fixation in many cases. Wide variability in
horizontal plane angulation was confirmed in this study as
well.
A path of least resistance technique can be used to deter-
mine the angle of screw insertion.32 With this method, a high-
speed burr or a rongeur is used to remove a small area of pos-
terior cortical bone over the pedicle starting point. An awl is
then advanced along a general anteromedial trajectory while
Figure 131.1. Line drawing depicting the starting point for tho- the surgeon uses tactile feedback to confirm that the awl is
racic pedicle screw placement in the thoracic vertebrae from T4 to smoothly advancing through the cancellous bone. However, in
T10, as described by Vaccaro et al.30 The superior facet (SF), pedicle a cadaveric study using 5-mm screws, and without the benefit of
(P), and the transverse process (TP) are depicted. The starting point radiographic imaging, this technique was associated with a high
for pedicle screw insertion is located at the intersection of a horizon- cortical penetration rate of 41%.32 Violations were fairly evenly
tal line drawn parallel to the superior border of the TP and a vertical
divided between the medial cortex (21 screws) and the lateral
line drawn through the middle of the SF.
cortex (16 screws). In the same study, cadaveric dissections and
CT scans were utilized to determine nearby anatomic structures
at risk from excessively long or errant screw placement.
Depending on the level and side, these structures included the
Vaccaro et al proposed pedicle screw starting points based on crus of the diaphragm, aorta, azygous vein, esophagus, hemi-
a cadaveric study of 17 mostly central Asian specimens azygous vein, inferior vena cava, cardiac atrium, parietal pleura,
(Fig. 131.1).31 From T4 to T10, the center of the pedicle was and lung (Fig. 131.2).
found to be located at the intersection of a longitudinal line A variation of this approach that may be particularly useful
drawn through the center of the superior articular facet and in patients with scoliosis is the funnel technique.33 After esti-
a horizontal line at the superior border of the transverse pro- mating the location of the pedicle based on local anatomic
cess. Caudad to T10, there was a gradual shift of the pedicle landmarks, a 6- to 10-mm cortical opening in the posterior lam-
toward the middle or caudad border of the transverse process. ina is created with a rongeur. A small curette is used to gradu-
This finding is similar to the suggested starting point of Roy- ally remove cancellous bone until the pedicle opening is visual-
Camille et al as 1 mm caudad to the inferior margin of the ized. Cancellous bone is then progressively removed to create a
cephalad facet joint in the midarticular line.28 Important cortical funnel from the mouth of the pedicle leading into the
additional observations from this study included significant isthmus. The pedicle is then sounded with a 2-mm pedicle
variability in pedicle diameter among specimens. Mean trans- probe to confirm its integrity.
verse diameter ranged from a mean of 4.5 mm at T4 to 7.8 Following initial probing of the pedicle with an awl, metallic
mm at T12. Mean pedicle angulation in the horizontal plane marker pins can be placed and intraoperative radiographs or
decreased from 13.9 medially at T4 to 0.3 medially at T12. fluoroscopy utilized to confirm intrapedicular location of the
In approximately half the specimens, the pedicle angle markers. Appropriate screw length can be estimated from the
diverged laterally at T12. The authors recommended use of lateral radiographic view.
preoperative computed tomography (CT) when practical to The technical demands of accurate TPS placement have
assist in determining pedicle screw placement and implant generated interest in use of the so-called image-guided surgical
size selection. navigation systems. Studies of different proprietary systems sug-
There has been significant variation in suggested pedicle gest that these modalities can improve placement accuracy but
screw starting points from different anatomic studies. Cinotti et at the expense of significantly greater operative time.
al4 examined 11 cadaveric spines and reported that, contrary to The authors of this chapter favor use of intraoperative fluo-
the findings of Vaccaro et al and Roy-Camille et al, the pedicle roscopic imaging whenever possible. Screw path inclinations
axis most commonly intersected the lateral two thirds of the can be estimated from an intraoperative lateral radiograph.
superior facet as opposed to the middle. Among all 99 thoracic These estimates are then used to position fluoroscopy to achieve
vertebrae evaluated, no pedicle axis was found medial to the perfect anteroposterior views sequentially for each vertebral

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1414 Section XII Trauma

resistance to pullout.17,38 However, routine intraoperative fluo-


roscopic visualization provides limited protection against exces-
sive anterior cortical penetration, and due to the significant
E
L risk of major vascular injury to the aorta and vena cava, inten-
tional bicortical fixation is generally not recommended. Safe
Az screw lengths have been suggested as 30 mm at T1-2, 35 mm at
Ao T4-5, and 40 mm at T5-6.22 Maximizing screw length, thread
area, and minor diameter given limitations of local anatomy
appears to yield optimal resistance to both pullout and bending
loads.
Although cortical breech occurs at a relatively high rate with
pedicle screw placement in the thoracic spine, it has been sug-
8 gested that medial breeches of up to 4 mm may be acceptable
due to a safety zone provided by a 2-mm epidural space and
2 mm of subarachnoid space.12 In terms of lateral pedicle viola-
tions, breeches of up to 6.8 mm may also be acceptable due to
protection from the rib head.7 Anterior cortical vertebral body
RP LP
penetrations of greater than 4 mm may threaten major vascular
or visceral structures.32

Figure 131.2. Anatomical structures anterior to the T8 vertebral


body, which are at risk when placing thoracic pedicle screws. Depicted EXTRAPEDICULAR TECHNIQUE
are the intended trajectories of the left and right pedicle screws and
the anatomical structures that fall within these trajectories. L, lung; When narrowness of pedicle diameter prevents placement of a
Az, azygous vein; Ao, aorta; E, esophagus. (Used with permission from fully intrapedicular screw, an extrapedicular placement tech-
Vaccaro AR, Rizzolo SJ, Balderston RA, et al. Placement of pedicle nique has been suggested.7,15 Utilizing this technique, a starting
screws in the thoracic spine. Part II: An anatomical and radiographic
point is selected along the lateralmost portion of the dorsal
assessment. J Bone Joint Surg Am 1995;77[8]:1204, Figure 3).
aspect of the transverse process. This point is located within the
rostral one third of the tip of the transverse process. Alterna-
tively, a starting point can be selected just rostral to the tip of
level instrumented. The horizontal pedicle angle is determined the transverse process. An awl is advanced by hand between the
from a preoperative CT study, and the fluoroscopy unit is transverse process and the adjacent rib. If the starting point is
angled appropriately to achieve an axial view down the pedicle within the tip of the transverse process, an insertion angle per-
on one side. The center of the pedicle outline is marked with a pendicular to the plane of the posterior elements is selected to
high-speed burr, and a straight 2-0 curette is used to probe the avoid injury to the neurovascular bundle. Using the alternative
posterior portion of the pedicle. Because of the greater medial starting point cephalad to the articulation of the transverse pro-
angulation of upper thoracic pedicles, a small laminotomy can cess and adjacent rib, a slightly caudally directed angle is
be helpful in guiding preparation of screw holes at T1 and T2. selected obliquely following the adjacent rib medially toward
A ball-tip probe is placed and visualized fluoroscopically to con- the costovertebral junction (Figs. 131.3A and B). Tactile feed-
firm position. A pedicle probe is then used to complete the back from the rib is used to guide preparation of the screw path
pedicle pathway to an appropriate depth. throughout its course from the transverse process to its entry
Matching of screw diameter to pedicle width represents a point into the superolateral portion of the anterior pedicle as
critical decision with respect to this fixation technique. Selection it joins the vertebral body. Given direct apposition of the pleu-
of screw diameter strictly on the basis of measured pedicle ral lining to the inferolateral pedicle, hugging the rib through-
diameter would result in a number of cases in which several out the extrapedicular screw path reduces the risk of injury to
levels would be considered unavailable for pedicle screw instru- pleura, lung, and neural elements. The ideal point of entry into
mentation. Although the smallest available screw diameter the vertebral body is at the superior costal facet. A depth gauge
often exceeds the smallest thoracic pedicle diameter measured is utilized to determine appropriate screw length and confirm
on preoperative CT images, expansion of the pedicle during the presence of bone margins circumferentially. A properly
placement of such screws can occur and is not always associated positioned screw is contained within the pedicle rib unit,
with detectable pedicle wall fracture. The use of progressively defined as a space between the lateral pedicle cortex and
larger diameter taps can provide tactile feedback informing the medial rib cortex. Although dimensions in the general popula-
surgeon when full cortical purchase has been achieved through tion have not been reported, the average width of this space in
the isthmus. If a pedicle fracture occurs, the effect in terms of scoliosis patients has been reported as 11 to 14 mm increasing
overall construct stability remains largely unknown, although from cephalad to caudad.20
reported clinical series suggest that any compromise is likely Screws placed extrapedicular are often observed to traverse
small. It has been suggested that pedicle fracture during screw a portion of the superior end plate of the vertebral body. This
insertion may reduce pullout resistance by 11%.11 tendency is greatest in the proximal thoracic spine and may be
Greater screw insertion depth is associated with a higher due to under inclination of the screw path in a caudad direc-
number of cycles to failure in cephalocaudal and mediolateral tion. Underinclination places the supradjacent neuroforamen
loading in the laboratory, and bicortical fixation through the at risk, and end plate violation may contribute to adjacent seg-
anterior vertebral cortex appears associated with the greatest ment degeneration.

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Chapter 131 Anterior and Posterior Instrumentation Techniques Used in the Thoracic Spine for Treatment of Fractures 1415

A B

Figure 131.3. Axial (A) and sagittal (B) illustrations demonstrating the proper positioning of the extrape-
dicular thoracic screw as described in the text (Used with permission from Husted DS, Yue JJ, Fairchild TA,
Haims AH. An extrapedicular approach to the placement of screws in the thoracic spine: an anatomic and
radiographic assessment. Spine 2003;28[20]:2325, Figures 1A and B.)

Suggested advantages of extrapedicular screw insertion fixation.13 In cadaveric specimens, reported load to failures for
include potentially greater fixation strength from the ability to T1 through T4 transverse process 3.5-mm cortical screws were
place a larger diameter and longer screw that engages three or 562.5, 373.0, 241.0, and 287.0 N, respectively.
four cortices. Nevertheless, biomechanical testing of screws The number of vertebral levels and fixation points required
placed with the extrapedicular technique has yielded somewhat to provide adequate construct strength in the setting of specific
conflicting results. In general, data suggest that extrapedicular patterns of thoracic fractures and dislocations has not been
screws provide approximately 75% of the strength of trans- clearly established. Decreased range of motion following multi-
pedicular screws.24,34 White et al compared axial and sagittal level fusion in the thoracic spine is not as functionally significant
loading of 5.0-mm screws placed transpedicular versus extrape- as it is in the cervical or lumbar spine. Constructs that end at the
dicular and found that transpedicular screws were stronger in level of maximum thoracic kyphosis should be avoided if possi-
both load conditions. In axial pullout, failure loads were 584 ble to minimize patient discomfort and to reduce pullout forces
and 826 N, respectively, while with sagittal force, failure loads at the terminal fixation anchors, which are most vulnerable to
were 696 and 863 N, respectively. Although Dvorak et al7 origi- failure. In general, two to three levels of fixation cephalad and
nally reported superior strength associated with extrapedicular caudad to the levels of injury are considered sufficient in bone
fixation, their study has been criticized for employing external with normal mineral density. In osteopenic or osteoporotic bone,
fixator pins and an anterior vertebral cortical penetration tech- a greater number of levels may be required.
nique that is not typically performed in clinical practice. In many cases involving posterior-only stabilization, indirect
Although increased safety has also been suggested as a poten- decompression of the spinal canal and correction of traumatic
tial advantage of extrapedicular insertion, the risk of inadver- kyphosis can be accomplished by careful patient positioning
tent canal entry may be as great as with standard intrapedicular and undercontouring of the rods. The cephalad screws and
fixation. Using local anatomic landmarks and a 30 to 45 inser- hooks are captured first, and then the rods are reduced to cap-
tion angle, Dvorak et al7 reported a high rate of canal encroach- ture the caudad screws and hooks. Despite successful stabiliza-
ment and recommended use of preoperative CT measurements tion and eventual fusion, some loss of correction over time can
to guide extrapedicular screw placement. be expected unless supplemental anterior interbody recon-
Potential disadvantages of this technique include violation struction is performed (Figs. 131.4A to E).
of costotransverse and costovertebral joints. Whether this Cross-linking of long constructs provides significantly greater
results in clinically significant pain or other symptoms is resistance to screw pullout failure by creating a trapezoidal
unknown. transverse profile that is secured by a wedge of bone between
In the upper thoracic spine, transverse process screws may each pair of converging screws. However, the decreased conver-
be a fixation option if there is excessive concern regarding the gence of TPSs compared with lumbar screws reduces the effect
ability to safely place pedicle screws. Biomechanical testing has of cross-linking.
demonstrated that transverse process screws provide approxi- In osteopenic or osteoporotic bone, consideration should
mately half the pullout strength compared with pedicle screw be given to protecting screws at the end of a long construct.

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1416 Section XII Trauma

Figure 131.4. These images represent a thoracic injury that


occurred in a 30-year-old man who was a restrained passenger
in a high-speed, head-on motor vehicle crash. This patient was
neurologically intact. (A) A sagittal reconstruction of the tho-
racic computed tomography (CT) scan demonstrates a flexion
distraction type injury with a burst component that involves the
T5 and T6 vertebral bodies. Also evident are fractures of the
spinous processes of T3, T4, and T6. (B) The axial CT image of
the T6 vertebral body shows fractures of the anterior, middle,
and posterior columns (i.e., lamina fracture), but no evidence
of retropulsion of bone into the canal. (C) A sagittal
T2-weighted magnetic resonance image demonstrates fracture
of the T5 and T6 vertebral bodies as well as probable disruption
of the posterior ligamentous complex at this level. This patient
underwent a posterior fusion from T2 to T12 using a pedicle
screwrod construct and iliac crest autograft as shown in the
postoperative (D) anteroposterior and (E) lateral radiographs.
An anterior approach and decompression was not necessary in
C
this patient because of his intact neurological status. (continued)

End screws are exposed to significant bending moments and et al36 reported their consecutive series of 32 patients with
are susceptible to pullout or fatigue fracture of the respective unstable thoracic spine injuries. About 222 screws were placed
vertebra. Maximizing resistance to bending loads is most impor- at T2-L1. Of note, patients with pedicle diameters of less than
tant in the proximal thoracic spine rostral to the apex of kypho- 7 mm on preoperative CT were excluded. In general, four
sis. In this region, if larger diameter convergent screws cannot screws were placed above and four screws placed below the
be utilized, consideration should be given to employing a level of injury, while avoiding placement of the construct end
paired hookclaw construct or protecting the most cephalad at the level of maximum thoracic kyphosis. At median 22-month
screw with an associated hook anchor. follow-up, there were no implant-related complications reported.
Sagittal plane correction was well maintained with no cases dem-
onstrating significant loss of reduction.
CLINICAL OUTCOMES
Kuntz et al19 reported their experience with 29 trauma
Three prospective clinical studies have been reported concern- patients undergoing placement of TPSs using fluoroscopic
ing the use of TPSs in treatment of traumatic spine injury. Yue guidance One hundred eleven of 209 screws placed exceeded

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Chapter 131 Anterior and Posterior Instrumentation Techniques Used in the Thoracic Spine for Treatment of Fractures 1417

D E

Figure 131.4. (Continued)

the measured diameter of the respective pedicle based on pre- The use of an interbody cage carries several advantages
operative imaging. Nevertheless, there were no implant-related compared with structural bone graft alternatives. The harvest
neurological deficits, visceral injuries, or screw failures observed. site morbidity associated with iliac crest or doubled stacked
One patient underwent reoperation for repositioning of a mal- autologous fibula is avoided. The early period of graft resorp-
positioned screw. tion and structural weakness is eliminated. Well-designed cage
Fisher et al10 described their experience with 23 patients systems now also provide a wide array of options in terms of
and 201 TPSs. Although postoperative CT imaging revealed a cross-sectional diameter, length, and end plate angulation to
high 33.8% rate of pedicle violation (36 lateral, 27 medial, and accommodate the vast majority of reconstruction needs encoun-
5 anterior), the authors felt that 98.5% of screws were in accept- tered.
able position in terms of threats to local anatomy. No neuro- Theoretical disadvantages of interbody cage constructs
logical, vascular, or visceral implant-related complications were include the relative absence of compressive forces acting on
identified. bone graft material housed inside a rigid cage device. Delayed
fusion or increased rates of nonunion may result. Nevertheless,
an evolving theory of interface bioincorporation resulting in
ANTERIOR INTERBODY CAGES macrolock stability has been proposed to explain the long-
term stability apparently provided by contemporary interbody
In the setting of acute thoracic spinal trauma, and exclusive of cage reconstruction even in the absence of radiologic evidence
thoracolumbar-level injury, the use of anterior instrumentation of solid osseous fusion.30 This concept supports the use of bio-
is most commonly indicated for immediate stabilization follow- integratable glass ceramics to coat implants to promote
ing anterior surgical decompression of the spinal canal. In the osteointegration of such devices.
absence of a possible incomplete spinal cord injury and ongo-
ing cord compression, the fixation strength afforded by con-
BIOMECHANICAL PRINCIPLES
temporary posterior segmental implant options is such that
posterior-only stabilization is often sufficient to allow early Biomechanical studies addressing the use of interbody cages in
patient mobilization and rehabilitation. An exception may the thoracic spine are sparse. The most common complication
occur in cases of significant kyphotic deformity in which case observed with use of interbody cages is postoperative subsid-
the provision of supplemental anterior interbody support can ence. Lowe et al21 performed biomechanical testing with cadav-
greatly reduce the stress on posterior fixation and promote eric specimens and demonstrated that the maximum load to
healing without loss of reduction and recurrent sagittal plane failure of the vertebral end plate occurs in the posterolateral
deformity. In this setting, the addition of an anterior interbody regions anterior to the pedicles. Minimum load to failure
cage significantly reduces the forces borne by the posterior occurs in the center of the end plate between T1 and T6 and
fixation. The two most frequently utilized forms of anterior in the anterocentral region of the end plate in the lower tho-
instrumentation in the thoracic region are interbody cages and racic spine. Reduced load to failure was also observed with
anterior plate/screw (or anterior rod/screw systems). smaller diameter hollow rod indenters. These findings suggest

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1418 Section XII Trauma

that the risk of subsidence may be lowered by maximizing cage Use of newer expandable cages reduces the requirement of
diameter so as to take advantage of the increased strength of performing distraction prior to implant placement. In the set-
the peripheral end plate as well as by using cage endcaps to ting of intact anterior and posterior longitudinal ligaments,
enhance surface area contact. It should be noted, however, that cage expansion restores anatomic height and provides addi-
the use of endcaps significantly decreases the area of direct tional immediate stability. As with static cages, maximizing end
contact between graft material and end plate and may be asso- plate contact between cage and adjacent vertebrae allows opti-
ciated with greater nonunion risk. mal load sharing while minimizing point-loading that increases
In the same study, Lowe et al reported only a marginal the risk of subsidence. However, the versatility of expandable
decrease in end plate compressive strength following removal of cages comes at the expense of reduced cage volume for con-
the anterior third of the end plate. The authors concluded that taining graft material. It should also be noted that cage expan-
a reasonable reconstruction strategy included partial removal of sion leads to creation of new voids within the cage that may
the anterior end plate followed by positioning of the interbody benefit from supplemental graft material. Ideally, the interbody
implant on the remaining end plate to provide the optimal cage should lie on the sagittal gravity line of the anterior col-
combination of stability and a favorable fusion environment.21 umn when the patient is in the upright position. This align-
ment promotes stability of the implant while minimizing shear
forces that may lead to progressive tilting of the implant and
SURGICAL TECHNIQUE possible dislocation.
In most cases, interbody cage placement is insufficient to
Principles of anterior interbody cage reconstruction derive restore adequate stability to the thoracic spine following trau-
from techniques developed for anterior stabilization with struc- matic destabilization and supplemental anterior and/or poste-
tural bone grafts. The patient is placed in a strict lateral decu- rior fixation is required (Figs. 131.5A to F). When used as a
bitus position to simplify visualization of implant orientation. stand-alone device following corpectomy, interbody cages are
Exposure of the fractured level(s) includes identification of the at risk for gradual displacement through a mechanism described
anterior and posterior borders of the vertebral body and the as pole-vaulting. This term describes a situation in which the
location of the spinal canal. Anatomic orientation is most read- cephalad vertebra translates anteriorly relative to the caudad
ily achieved by beginning the dissection at the vertebral bodies vertebra resulting in progressive tilting of the interposed cage.
cephalad and caudad to the level of injury.
Once adequate exposure has been achieved, decompression
of the canal is performed as necessary. Minimizing removal of TRANSPEDICULAR CAGE PLACEMENT
vertebral body bone to that which is necessary for canal decom-
pression and to allow placement of an interbody cage in direct Although most thoracic-level cages are currently placed through
opposition to adjacent end plates provides the optimal biologi- an open thoracotomy approach, the introduction of expand-
cal environment for rapid fusion. Sufficient bone must be able cages allows anterior interbody placement through a pos-
removed from the vertebral body on the side contralateral to terior transpedicular approach. This technique avoids the risks
the side of approach to allow midline positioning of the cage. and morbidity associated with thoracotomy but requires signifi-
Preservation of the anterior and posterior longitudinal liga- cantly greater dissection and surgical manipulation directly
ments when possible provides a tensile counterforce against a around the spinal canal and regional nerve roots.
well-positioned cage that promotes immediate stability and For a single-level thoracic burst fracture, through a poste-
reestablishes normal anatomic length and alignment. Complete rior surgical approach, a hemilaminectomy is performed of the
removal of end plate cartilage and avoidance of end plate corti- injured level on the side of greatest canal compromise until the
cal fracture enhance fusion and stability. Controlled perfora- ipsilateral pedicle stalk is well visualized. Although the trans-
tions of the central end plate not in contact with the cage cir- verse process is freed from the pedicle, it is not removed and
cumference may promote neovascularization without significant serves as a protective barrier for the exiting nerve root. A hemi-
loss of end plate support. Creating a small posterior lip in the laminectomy of the cephalad level is performed as well.
end plates with a high-speed burr provides added security Discectomies are then performed cephalad and caudad to the
against posterior migration of the cage into the canal. With use fractured vertebra. The ipsilateral pedicle is completely
of a static cage, intervertebral distraction assists in placement of resected. If adequate canal decompression requires, a complete
an optimally sized implant. An assistant can apply anteriorly laminectomy and bilateral pedicle resection can be performed.
directed pressure on the back of the patient to provide lordosis Through the transpedicular space, resection of the posterior
and additional space for the cage. Intraoperative fluoroscopic two thirds of the fractured body can be accomplished with
or radiographic imaging is used to assess implant position. curettes, rongeurs, or a high-speed burr. This step serves to
Often, additional tissue resection is required to achieve mid- decompress the spinal canal as well as prepare the space for
line cage positioning. Tactile feedback when the cage is bal- cage placement. Pedicle screws are placed in the vertebrae
loted can provide useful information regarding the type of tis- cephalad and caudad to the level of injury and distraction is
sue that must be removed. A soft springy recoil suggests that performed across these screws to assist with cage placement.
disc tissue is blocking placement. Bone graft material is placed within the expandable cage, which
In addition to cage diameter and length, in many systems is then inserted in collapsed configuration and expanded in
end plate angulation must also be selected. A combination situ. Additional graft material can then be placed within the
should be fashioned that yields maximum area of contact with voids created by cage expansion. The cage should be positioned
the end plates of the adjacent intact vertebrae and results in a in direct contact with end plates of the adjacent intact verte-
cage axis as vertical as possible when the patient is in the upright brae. Compression across the posterior pedicle screws estab-
position. lishes final correction of sagittal alignment.1

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Chapter 131 Anterior and Posterior Instrumentation Techniques Used in the Thoracic Spine for Treatment of Fractures 1419

A B

C D

Figure 131.5. These images represent a thoracolumbar injury that occurred in a 24-year-old man
restrained backseat passenger in a head-on motor vehicle crash. Upon presentation, the neurological status
of this patient was a grade B on the American Spinal Injury Association scale. (A) A sagittal reconstruction of
the thoracic computed tomography (CT) scan demonstrates a flexiondistraction type injury with a burst
component that involves the T12 vertebral body and superior end plate depression of the T9, T10, and T11
vertebral bodies. Also evident are fractures of the spinous processes of T10, T11, and T12. (B) The axial CT
image of the T12 vertebral body shows fractures of the anterior, middle, and posterior columns with signifi-
cant comminution and canal compromise. (C) A sagittal T2-weighted magnetic resonance image demon-
strates fracture of the T9 to T12 vertebral bodies as described above, as well as disruption of the posterior
ligamentous complex posterior at the T11-T12 level. There is significant retropulsion of bone into the canal
with spinal cord compression and edema. This patient had a staged procedure. Initially, he underwent an
anterior T12 corpectomy with implantation of a titanium expandable cage, the center of which was packed
with local autograft. This fixation was supplemented anteriorly with a single pedicle screwrod construct.
Four days later, the patient underwent a posterior spinal fusion from T8 to L2 using a pedicle screwrod
construct and iliac crest autograft. The postoperative (D) anteroposterior and (E) lateral radiographs are
shown. (continued)

LWBK836_Ch131_p1411-1423.indd 1419 8/26/11 10:09:49 PM


1420 Section XII Trauma

Figure 131.5. (Continued) (F) A postoperative sagittal


reconstruction CT image demonstrates the location of the
expandable cage and the bone graft within the center of the
cage. The decision to proceed with an anterior corpectomy
and fusion initially was made due to the patients incomplete
E F neurological status upon presentation.

CLINICAL OUTCOMES revision cases involved thoracic-level surgery. All failed thoracic
reconstructions involved cage reconstruction with supplemen-
There is relatively little published data regarding trauma-
tal posterior instrumentation alone.
specific outcomes following anterior interbody cage recon-
In the same study, using the Bridwell grading system, a grade
struction of thoracic spinal trauma. Most studies involve
1 or 2 osseous fusion was observed on plain radiographs in 93%
heterogeneous patient populations that include a majority of
of patients at average 32-month follow-up. This rate compares
nontrauma-related indications. In such mixed patient popula-
favorably to previous fusion rates of 93% reported for struc-
tions, the use of titanium interbody cages appears associated
tural autograft.5 Reliable fusion was observed despite a mean of
with durable radiographic and clinical results. Eck et al9
4 mm of cage subsidence. The authors noted their practice of
reported minimum 2-year follow-up on 50 patients surgically
packing morselized autograft anterior to the cage to promote
treated with anterior titanium cage reconstructions in the tho-
fusion in this location where it is readily visualized radiographi-
racic and lumbar spine and observed cage settling greater than
cally and serves to resist anterior column forces. Because of the
2 mm in 47% of corpectomy levels but no cases of cage migra-
relatively high failure rate observed in the thoracic spine, the
tion or failure.
authors also comment on their increased use of both supple-
Although different cage materials are currently available,
mental anterior and posterior instrumentation to augment
titanium cages are currently in widest use. Metallic cages are
thoracic-level cage reconstructions. These findings are sup-
readily imaged with standard radiography allowing easy
ported by similar results reported by Karaeminogullari et al16
follow-up in terms of implant position and stability. Development
using titanium mesh cages in which supplemental anterior-only
of a fusion mass within metallic cages is often difficult, however.
fixation or short-segment posterior fixation was associated with
Eck et al9 observed greater radiographic fusion rates when
loss of deformity correction and cage settling.
bone graft is placed outside as well as within metallic cages but
attributed this difference to the greater ease of assessing fusion
status outside such cages as opposed to a true difference in
fusion rates. Using the Bridwell grading system for assessing ANTERIOR PLATE/ROD AND
anterior interbody fusion, an 81% rate of definite or probable SCREW FIXATION
fusion was observed at minimum 2-year follow-up.3,9
The use of titanium mesh cage reconstruction may be asso- Anterior plate/rod and vertebral body screw fixation can add
ciated with higher failure rates in the thoracic spine compared significantly to spinal stability and may be particularly critical in
with the thoracolumbar or lumbar spine. Dvorak et al8 retro- supplementing interbody cage reconstruction in the thoracic
spectively reported their experience using titanium mesh cages spine. Regional variation in vascular and visceral anatomy
following thoracic and lumbar vertebral body resection in 43 should be considered when deciding whether to utilize ante-
mostly traumatic cases. In all cases, supplemental anterior plate rior plate/rod and screw fixation systems in the thoracic spine.
or rod and/or posterior pedicle screw and rod fixation was uti- Such implants are often positioned in proximity to such vulner-
lized. Early loss of deformity correction was observed in 16% able structures and pose potential risk if there is device loosen-
requiring surgical revision in 14%. Eighty-three percent of the ing and migration. As a result, such anterior instrumentation is

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Chapter 131 Anterior and Posterior Instrumentation Techniques Used in the Thoracic Spine for Treatment of Fractures 1421

most commonly utilized in the lower thoracic and thoracolum- SURGICAL TECHNIQUE
bar spine. Increased caution must be exercised in using this
technique in the thoracic spine proximal to T9. In the trauma setting, anterior thoracic plate/rod fixation is
most commonly applied after placement of an interbody graft
BIOMECHANICAL PRINCIPLES or cage (see Figs. 131.5D and E). Exposure includes the verte-
bral body cephalad and caudad to the level(s) of injury. In par-
The first vertebral body screws were placed midbody and paral- ticular, the pedicles, infrapedicular neuroforamen, posterior
lel to the end plates. Subsequently, Horton et al14 demonstrated body margin, anterior body margin, and cephalad discend
that proximity to the end plates was important for improving plate junction must be clearly defined. The postoperative rela-
fixation strength of vertebral body screws. Ogon et al25 also tionship between adjacent vascular structures and the planned
showed that triangulated double-screw fixation provides 79% anterior instrumentation must be predicted, and if there is sig-
greater resistance to pullout and 73% greater resistance to per- nificant risk that implants will directly contact the aorta or vena
pendicular loads compared with single-screw fixation. The use cava then alternative implants should be considered or the use
of two-rod constructs is associated with increased construct of anterior instrumentation abandoned altogether.
strength and resistance to fatigue failure compared with single- Different systems allow for variation in terms of the number
rod constructs. Finally, increasing screw diameter improves of vertebral body screws utilized per level and the selection of
fixation strength but may increase the risk of crack propagation reinforcing staples, plates, or rods. In general, if two screws are
and fracture-related failure of fixation. Although these observa- utilized at a given level, the posterior screw is positioned first.
tions should be kept in mind while planning anterior instru- The starting point for the posterior screw is positioned approx-
mentation strategies, options are typically limited by the imately 1 cm below the cephalad end plate and 1 cm anterior to
constraints of local anatomy, particularly the small size of more the posterior body margin. The screw hole is directed approxi-
proximal thoracic vertebrae and vulnerable regional anatomic mately 10 anteriorly away from the spinal canal. Inadvertent
structures. Mohamad et al23 performed a biomechanical study anterior positioning of the starting point can result in a screw
using cadaveric thoracic vertebral specimens and demonstrated directed toward the spinal canal and neurological injury or
significantly greater failure loads with two-screw constructs prominent instrumentation that is in increased proximity to
compared with single-screw constructs, but the increased resis- the great vessels.
tance to pullout was only 25%.23 The same study also revealed If the system incorporates a plate as the longitudinal stabi-
different failure modes with single-screw constructs plowing lizer, the flare of the proximal vertebral body can be reduced
through bone while two-screw constructs failed by acute frac- with a burr or rongeur to allow the plate to site flat. Screw
ture of the body or pedicles. length is estimated from preoperative CT imaging if available

A B

Figure 131.6A. This patient had an L1 burst fracture with significant canal compromise and a neurologi-
cal deficit and underwent an L1 corpectomy with an allograft humerus strut supplemented with local
autograft bone and stabilized with a double-pedicle screw/rod construct. This is depicted in the postopera-
tive (A) anteroposterior and (B) lateral radiographs. Note that the posterior and anterior pedicle screws in
the T12 and L2 bodies converge on one another in the anteroposterior and/or lateral views in order to
increase pullout strength.

LWBK836_Ch131_p1411-1423.indd 1421 8/26/11 10:09:51 PM


1422 Section XII Trauma

Neurological deficit with anterior


compression
Yes No

Posterior ligamentous injury Posterior ligamentous injury

Yes No Yes No

Combined anterior/ Anterior decompression Significant compromise


posterior approach and fusion of anterior column

Yes No
Figure 131.7. Algorithm for surgical
Posterior fusion/ decision making for thoracolumbar frac-
Consider additional ture. The two most important factors in
anterior approach Treat in brace with close making the decision of which surgical
for anterior column radiographic follow-up approach is necessary are the neurologi-
support if necessary cal status of the patient and the status of
the posterior ligamentous complex.

and confirmed by use of a depth gauge after pilot hole prepara- polytrauma victims. For patients requiring anterior decompres-
tion. Caution should be exercised in using fluoroscopy to assess sion or with significant kyphosis and sagittal plane instability,
screw length. The circular perimeter of the vertebral body gen- the use of supplemental anterior interbody cages and anterior
erates a blind spot on fluoroscopic imaging such that excessive plate/rod fixation systems provides additional stability that may
penetration of the distal cortex is not clearly visualized. Not all reduce the risk of recurrent deformity and posterior fixation
systems require pilot hole preparation prior to screw place- failure. Good understanding of biomechanical principles gov-
ment. The cancellous bone of the vertebral body typically allows erning implant fixation in the thoracic spine as well as comfort
placement of screws that are not self-tapping after defining the with the unique regional anatomy of the thoracic spine allows
starting point with an awl. safe and effective application of these contemporary implant
The position of the anterior screws, if they are used, is typi- options.
cally determined by posterior screw position but is often
designed to be placed directly transverse across the body paral-
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