Beruflich Dokumente
Kultur Dokumente
February 2017
Autobiography Instructions:
- 750 word limit
- Single-spaced
- 1 inch margins
- 12pt font
- Document must describe the life (from birth to demise/end fate) of a T cell
expressing an anti-gp100 TCR which existed as a nave CD8 + T cell in the
periphery of a melanoma patient becoming activated after the patient was
treated with an oncolytic vaccine
Rubric:
Category: Student
Grade:
Birth Correct anatomical location/station identified. /1
Correct stage at egress identified. /1
Correct method of egress/exit identified. /1
Section Total: /3
Education Correct anatomical location/station identified. /1
Description of affinity. /1
Correct reasoning for affinity. /1
What would be considered high affinity? /1
Correct identification of method of egress/relevant /2
station(s). /1
Correct indication of T cell type at egress. /1
Descriptor of nave T cell lifespan. /1
Descriptor of signals required for nave T cell maintenance.
Section Total: /9
Pre- Correct indicators of location(s)/station(s) applicable. /3
activation Descriptor of entry to the appropriate organ/tissue/station. /3
life Description of subsequent intraorgan migration. /2
Descriptor of cell type restriction mechanism. /2