Neuroantomic Bipolar Disorder

Risk Factors Circuits

Ashley Dean
Anatomical
Changes of Brain
RNSG1263
Unknown Contributing
Factors

Genetic Limbic-Thalamic-Cortical
&
Limbic-Striatal-Pallidal-Cortical
Circuits
Biochemical

Frontal & Temporal Lobes Hippocampus

Neuroanatomic Of Forebrain
Circuits

Pre-Frontal Cortex Enlargement of Third

and Lateral Ventricles Reduction in #
of Glial Cells
Basil Ganglia & Reduction in
Parts of the Limbic System Volume of Grey Matter
Reduction in #
of Neurons
Genetics

Manifestations Bipolar Disorder Complex and

Non-Mendelian

Depression Promiscuous
Behaviour Iinteractions of
Multiple Genes
Anxiety Overspending

genomic imprinting,
Phobias Verbally & mitochondrial inheritance
Physically Abusive
Complications
Suicide Substance Abuse

Inability to
Smoking Care for Self
Higher Incident of
Physical Illness Financial Ruin
Alcohol Abuse

Heart Disease Migraines Social Alienation Reduction concentration

Cocaine or Marijuana Increase in plasma of HVA a major
Noradrenaline during Mania Dopamine metabolite

Asthma Cancer Death

Reduced concentration Depleted levels of Noradrenaline,
of Serotonin metabolite Seratonin and/or Dopamine
5-HIAA in CNS during Depression
GI Disorders Heart Disease Hospitalization
or Jail

Reduced density of Reduction of choline

Diabetes Loss of Family, Serotonin 1A Receptors in erythrocytes
Friends& Job

Biochemistry