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This formula is based on two recent population studies 1,2, both based in the
Intensive Care Unit setting. One study calculated a multiplier of 4.8, the other
of 5.02. Although most of our patients are not as unwell as these patients,
these are the only studies with an evidence base for transfusion volumes.
Some other messages from these studies:
o The age of the patient does not affect the transfusion formula.
o Measuring the haemoglobin 7 hours after the transfusion gives the
same result as measuring the haemoglobin straight after the
transfusion.
o The speed of transfusion does not affect final haemoglobin.
Conflict of Interest.
PD is the first author of reference 2. He is unrelated to the PD in reference 1.