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Luminex 100/200 System

2015/2016 Catalog

xMAP Technology
Products and Services
Instruments

Luminex 100/200 System


Software

Vision
Breakthrough solutions to improve
health and advance science
Reagents

Mission
Luminex transforms the way our customers
perform biological testing. We pioneer
comprehensive yet simple solutions to improve
outcomes and reduce overall costs.
Service

Every day we work to enhance the health, safety


and quality of life for all.
Training

2
Instruments
Introduction
Table of Contents xMAP Technology Overview
Luminex 100/200 System
Instruments
MAGPIX
This catalog includes Luminex life science Luminex 200
products and services and is not intended to be FLEXMAP 3D
a comprehensive menu of applications available

Software
from Luminex. Life science products include Software
xMAP instruments, xPONENT software and
xPONENT Software Solutions
xMAP reagents & accessories. Services include Software Options
instrument service plans and Luminex Learning
training courses. Reagents and Accessories
MagPlex Microspheres
Also offered by Luminex but not included in MagPlex-TAG Microspheres

Reagents
this catalog are products and services MicroPlex Microspheres
specifically designed for specialized markets, LumAvidin Microspheres
such as Molecular Diagnostics. SeroMAP Microspheres
xMAP Instrument Reagents
xMAP Antibody Coupling Kit
You can learn more about Luminex and these
Magnetic Separators
additional products and services by contacting
your local Luminex representative or by visiting Service
our corporate website at www.luminexcorp.com.

Service
Instrument Service Plans

Training
Luminex Learning

About Luminex
Strategic Partnerships

Training
Locations & Contact Information

*All of the products contained in this catalog are intended for research use only.
3
xMAP Technology Overview

Bead-based Multiplexing of Up to 500 Bioassays per Well How xMAP Technology Works
Open-architecture xMAP Technology enables multiplexing of biological tests First, Luminex uses proprietary techniques
(assays), reducing time, labor, and costs over traditional methods. Systems to internally color code microspheres with
using xMAP Technology perform discrete assays on the surface of color-coded various fluorescent dyes. Through precise
beads known as microspheres, which are then read in a compact analyzer. Using concentrations of these dyes, up to 500
multiple lasers or LED and high-speed digital-signal processors, the analyzer reads distinctly colored bead sets can be created,
multiplex assay results by reporting the reactions occurring on each individual each of which can be coupled to a target-
microsphere particle. specific molecule. These target-specific
molecules may be antigens, antibodies,
xMAP Technology Advantages and Benefits oligonucleotides, enzyme substrates, or
receptors. After an analyte from a test sample
Speed/High-Throughput - Because each microsphere serves as an individual is captured by this target-specific molecule,
test, a large number of different assays can be performed and analyzed a reporter molecule, labeled with a different
simultaneously fluorescent dye, is introduced to complete the
Versatility - A single xMAP Technology-based system can perform assays using reaction on the surface of each microsphere.
several different methods and chemistries, including nucleic acid hybridization, Next, the microspheres internal dyes are
antigen-antibody binding, enzyme reactivity, receptor-ligand binding and other excited by the laser or LED, identifying the
protein interactions microsphere set. A second laser or LED excites
Accuracy - xMAP Technology generates a real-time assessment and accurate the fluorescent dye on the reporter molecule.
quantification of the biological interactions being tested Using these signals, highspeed digital-signal
Flexibility - xMAP Technology can be used in a variety of applications ranging processors identify each individual microsphere
from life science research to clinical diagnostics, food safety and bio-defense and quantify the amount of target molecule
Reproducibility - High-volume production of xMAP microspheres within a single bound to its surface.
lot allows reduced variability that solid-phased flat arrays cannot provide

4
xMAP Technology Overview

Luminex internally color- The microspheres can The microspheres pass


codes microspheres with be coupled with reagents through a red laser or LED,
precise concentrations specific to a particular which excites the internal
Nucleic Acid Assay Immunoassay
of multiple fluorescent bioassay, such as dyes to distinguish the
dyes, yielding up to antigens, antibodies, microsphere set. Then a
500 distinctly colored oligonucleotides, enzyme green laser or LED excites
bead sets. substrates, or receptors. the fluorescent reporter
dye to determine the
result of the assay.

Enzyme Assay Receptor-Ligand

Current xMAP Technology Applications


Drug Discovery/Genomics Diagnostics
Detecting single nucleotide polymorphisms (SNPs) for Screening for genetically inherited diseases such as cystic fibrosis
pharmacogenomic applications Serological screening for infectious diseases such as hepatitis
Expression analysis with transcriptional profiling Multi-analyte profiling of hormone levels
HLA tissue typing for transplantation
Drug Discovery/Proteomics Multiplexed autoimmune and allergy testing
High-throughput screening of potential drug compounds by
inhibition of enzymatic targets such as kinases or proteases Basic Research
Kinase selectivity screening of drug candidates against multiple Gene expression analysis
common kinases Genotyping
Measurement of serum analytes in animal and human clinical trial Protein expression analysis
subjects Antibody avidity analysis
Multianalyte profiling of drug and drug metabolites for purposes of Animal-model serum analyte profiling
toxicology and drug metabolism studies Antibody epitope mapping
Drug target validation using receptor-ligand analysis Enzyme/substrate research
Protein-protein interaction analysis

5
Instruments

Luminex Instrumentation

Multiplexing Solutions for Proteins and Nucleic Acids


Luminex offers three different xMAP-based instruments, covering a range of laboratory and budgetary needs. Installation Qualification (IQ) and
Operational Qualification (OQ) validation protocols are available for each of the above instruments. Contact Luminex for more details.

6
Instruments
Luminex Instrumentation Overview

MAGPIX Luminex 100/200 FLEXMAP 3D


Software xPONENT xPONENT xPONENT
Optics LED/CCD Camera Lasers/APDs/PMTs Lasers/APDs/PMTs
Hardware Fluorescent Imager Flow Cytometry based Flow Cytometry based
Bead Compatibility MagPlex MagPlex MagPlex
MagPlex-TAG MicroPlex MicroPlex
MagPlex-TAG MagPlex-TAG
SeroMAP SeroMAP
LumAvidin LumAvidin
Multiplex Capacity 50 100 (80 for MagPlex) 500
Read Time ~ 60 mins/96-well plate ~ 45 mins/96-well plate ~ 20 mins/96-well plate
~ 75 mins/384-well plate
Applications Protein/Nucleic Acid Protein/Nucleic Acid Protein/Nucleic Acid
IVD-cleared Assays Yes Yes Yes
Dynamic Range 3.5 logs 3.5 logs 4.5 logs
Microtiter Plate 96 well 96 well 96 well and 384 well
Dimensions, including computer Approx. 70cm x 60cm x 50cm Approx. 115cm x 60cm x 50cm Approx. 110cm x 62cm x 63cm
(Width x Depth x Height)
Weight (Analyzer) 17.5 kg (38.5 lbs) 49 kg (113 lbs) 77.1 kg (170 lbs)
Warranty 1 year 1 year 1 year

*The Luminex 100/200 & FLEXMAP 3D are class 1(I) laser products.
7
Instruments

MAGPIX
Luminex 100/200 System

Key MAGPIX Features


Multiplexing: Up to 50 analytes per sample volume
Sensitivity: Approximately 106 copies of DNA or single-digit picogram
levels of protein
Dynamic Range (Typical): >3.5 logs
Read Time: 96-well plate in 60 min (up to 4,800 tests/hour)
Daily Start-Up/Shut-Down: 15 min
Foot Print: 3 ft linear bench space

Commonly Ordered Parts & Accessories


Consumables Part Number
MAGPIX Calibrator Kit, 25 Uses MPX-CAL-K25
MAGPIX Performance Verification Kit, 25 Uses MPX-PVER-K25
MAGPIX Drive Fluid, 4 Pack MPXDF-4PK
Instrument Part Number Accessories
MAGPIX Instrument MAGPIX-XPONENT Heater Block for 96-Well Microtiter Plates CN-0224-01
Sample Probe Height Adjustment Kit CN-0263-01
MAGPIX is the simplest, most affordable and most portable Bar Code Scanner, USB CN-PC03-01

of Luminexs xMAP instruments. This compact multiplexing Spare Parts


Syringe Seal (Qty 4) for 6 month PM CN-0014-01
unit performs up to 50 different tests in a single reaction
Sample Probe Needle CN-0221-01
volume and reads a 96-well-plate in just 60 minutes. Air Filter, 4.5 x 4.5 CN-0257-01
MAGPIX features self-cleaning routines and magnetic bead Drive Fluid Filter CN-0258-01
compatibility (with MagPlex beads), making the instrument Sample to Valve Tubing Assembly CN-0259-01
easy to learn and easy to use. MAGPIX can be ordered with Waste Bottle Assembly CN-0261-01
a laptop PC instead of a desktop PC. Syringe, 500 L Ball End CN-0262-01
12-Month Preventive Maintenance Kit, MAGPIX CN-0287-01
Other
MAGPIX - xPONENT 4.2 IQ/OQ Protocol VP-MAGPIX-XPON4.2
MAGPIX - xPONENT 4.1 IQ/OQ Protocol VP-XPONENT4.1

8
Instruments
Included with the MAGPIX

Part Number MAGPIX-XPONENT


Description MAGPIX xPONENT 4.2 System
Core Instrument MAGPIX bead reader with: Sample probe-needle; Off plate reagent block; Waste bottle; Sample probe height
adjustment kit; Access door tool; Documentation
Available Power Cords (pick one nation) USA, Australia, Brazil, Denmark, Germany, Sweden, France, Belgium, Spain, Switzerland, Israel, UK, Italy, Japan,
India, China, S. Africa, Argentina, Korea, Taiwan
Bar-code scanner Optional, at no charge with purchase of new system
Heater Block (96-well plate) Optional, at no charge with purchase of new system
Included Software xPONENT 4.2 (3 seats),
Allele-call module (3 seats)
Remote Web Monitoring module (3 seats)
Optional Software (extra charges apply) LIS integration module
Automation interface module
Basic Security Module
21 CFR Part 11 Module (supersedes Basic Security)
Additional seats
Reagents Included MPX-CAL-K25, qty 1 (separately shipped)
MPX-PVER-K25, qty 1 (separately shipped)
MagPix Drive Fluid, qty 2 (ships with MAGPIX)
PC with Win 7 32-bit, US English PC, Desktop, USFF, WIN 7 with XPON 4.2 PC Laptop, WIN7 with XPON4.2
Dell Optiplex Ultra Small Form Factor Dell Latitude
Dell Warranty Transfer Dell Warranty Transfer
Stand, All-In-One Monitor/PC USFF
Dell 19 LCD monitor
Dell sound-bar
Dell Keyboard & mouse
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Instruments

Luminex
Luminex200
100/200 System

Key Luminex 200 Features


Multiplexing: Up to 100 analytes per sample volume
(80 on MagPlex microspheres)
Dynamic Range (Typical): >3.5 logs
Read Time: 96-well plate in 45 min (up to 12,800 tests/hour)
Daily Start-Up/Shut-Down: 30 min

Commonly Ordered Parts & Accessories


Consumables Part Number
Luminex 100/200 Calibration Kit, 25 Uses LX200-CAL-K25
Instrument Part Number
Luminex 100/200 Performance Verification Kit, 25 Uses LX200-CON-K25
Luminex 200 Instrument LX200-XPON3.1
Sheath Concentrate Pack (20X) 40-75680
xMAP Sheath Fluid, 20L 40-50000
The Luminex 200 set the standard for multiplexing with Accessories
over 8,000 units sold globally and more than fifty 510(k)- Sample Needle Height Alignment Kit CN-0015-01
cleared assays available. The ability to perform up to 100 Heater Block (XYP) CN-0017-01
different tests in a single reaction volume and to use either Automated Maintenance Plate CN-0206-01
magnetic beads or plain polystyrene beads makes this Bar Code Scanner, USB CN-PC03-01

instrument a popular choice for laboratories needing greater Spare Parts


Rear Air Filter CN-0001-01
flexibility. Additionally, the Luminex 200 is able to offer
Short Sample Probe CN-0006-01
higher sampler throughput with a 96-well plate read time of Long Sample Probe CN-0007-01
only 45 minutes. Sheath Filter w/Quick Disconnect CN-0010-01
Syringe Cylinder, w/Seal CN-0013-01
Syringe Seal (Qty 4) CN-0014-01
Intake Air Filter (Qty 5) CN-0027-01
6Month Preventative Maintenance Kit CN-0096-01
Other
Luminex 100/200 - xPONENT 3.1 IQ/OQ Protocol VP-XPONENT3.1

10
Instruments
Included with the Luminex 200

Part Number LX200-XPON3.1


Description Luminex 200 System with xPONENT 3.1
Core Instrument Luminex 200 flow-based bead reader with: Sheath Delivery System; X-Y Platform for 96-well plates; Sample
probe-needle; 1L sheath bottle, 1.2L Waste bottle; Sample probe height adjustment kit; Automated Maintenance
Plate; Heater Block (96 well plate); Documentation
Available Power Cords (pick one nation) USA, Australia, Brazil, Denmark, Germany, Sweden, France, Belgium, Spain, Switzerland, Israel, UK, Italy, Japan,
India, China, S. Africa, Argentina, Korea, Taiwan
Bar-code scanner Optional, at no charge with purchase of new system
Included Software xPONENT 3.1 (3 seats),
Allele-call module (3 seats)
Remote Web Monitoring module (3 seats)
Optional Software (extra charges apply) LIS integration module
Automation interface module
Basic Security Module
21 CFR Part 11 Module (supersedes Basic Security)
Additional seats
Reagents Included LX200-CAL-K25, qty 1 (separately shipped)
LX200-CON-K25, qty 1 (separately shipped)
xMAP Sheath Fluid (20L), qty 1 (ships with LX200)
Desktop PC with Win 7 32-bit, Dell Optiplex with 2 Port PCI RS232 Serial Adapter Card
US English & xPONENT 3.1 Dell Warranty Transfer
Dell 17 LCD monitor
Dell Keyboard & mouse

11
Instruments

FLEXMAP 3D

Key FLEXMAP 3D Features


Multiplexing: Up to 500 analytes in a single sample volume
Dynamic Range (Typical): >4.5 logs
Read Time: 96-well plate in 20 min (up to 144,000 tests/hour);
384-well plate in 75 min (up to 153,600 tests/hour)
Daily Start-Up/Shut-Down: 30 min

Commonly Ordered Parts & Accessories


Consumables Part Numbers
FLEXMAP 3D Calibration Kit F3D-CAL-K25
FLEXMAP 3D Performance Verification Kit F3D-PVER-K25
Sheath Fluid Concentrate Pack (20X) 40-75680
Sheath Fluid (20L) 40-50000
Instrument Part Number Accessories
FLEXMAP 3D Instrument FLEXMAP-3D-RUO FLEXMAP 3D Swivel Base CN-0216-01
Heater Block, 384-Well Microtiter Plate CN-0223-01
Heater Block, 96-Well Microtiter Plate CN-0224-01
The FLEXMAP 3D is Luminexs most advanced and versatile
Sample Probe Height Adjustment Kit CN-0263-01
multiplexing platform. Fast read time, compatibility with
384- Well Plate Probe Height Adjustment Tool CN-0298-01
both 96- and 384-well plates and ease of integration with Barcode Scanner, USB CN-PC03-01
front-end automation systems make the FLEXMAP 3D Spare Parts
the platform of choice for high-throughput applications. Syringe, 500 mL with Seal CN-0013-01
The platform uses both magnetic and non-magnetic Syringe seal (Qty 4) CN-0014-01
microspheres and is capable of simultaneously measuring Sample Probe Needle CN-0221-01
Off-Plate Reagent Block CN-0225-01
up to 500 genes or proteins from a small sample volume.
Fuse (6 AMP) CN-0226-01
Automated start-up, shutdown, and maintenance routines
Other
make the FLEXMAP 3D easy to use and maintain. FLEXMAP 3D - xPONENT 4.0 IQ/OQ Protocol VP-XPONENT4.0
FLEXMAP 3D - xPONENT 4.2 IQ/OQ Protocol VP-FM3D-XPON4.2

12
Instruments
Included with the FLEXMAP 3D

Part Number FLEXMAP-3D-RUO


Description FLEXMAP 3D xPONENT 4.2 System
Core Instrument FLEXMAP 3D flow based bead reader with: Sample probe-needle; Off plate reagent block; Waste container;
Sample probe height adjustment tool; Barcode Scanner; Heater Block 96-well; Heater Block 386- well;
Documentation
Available Power Cords (pick one nation) USA, Australia, Brazil, Denmark, Germany, Sweden, France, Belgium, Spain, Switzerland, Israel, UK, Italy, Japan,
India, China, S. Africa, Argentina, Korea, Taiwan, Pakistan
Included Software xPONENT 4.2 (3 seats),
Allele-call module (3 seats)
Remote Web Monitoring module (3 seats)
Optional Software LIS integration module
(extra charges apply) Automation interface module
Basic Security Module
21 CFR Part 11 Module (supersedes Basic Security)
Additional seats
Reagents Included F3D-CAL-K25, qty 1 (separately shipped)
F3D-PVER-K25, qty 1 (separately shipped)
Sheath Fluid (20L) qty 1 (Ships with FLEXMAP 3D)
PC with Win 7 32-bit, US English PC, Desktop, USFF, WIN 7 with XPON 4.2
Dell OptiPlex 7010 Ultra Small Form Factor
Dell Warranty Transfer
Arm Mounted ELO 19 Touch Screen Monitor
AX2010 USB Stereo Speaker System
Keyboard & Mouse

13
xPONENT Software Solutions
Software

14
xPONENT Software Solutions

Data Acquisition and Analysis for xPONENT Software Offers:


Luminex Instrumentation Automated daily operations Use of calibration and performance verification
kits to automate routine system maintenance as well as Startup, Shutdown,

Software
xPONENT is a modular and flexible software
package for controlling the MAGPIX, Calibration and Performance verification operations.
Luminex 100/200, and FLEXMAP 3D Normalization bead support for internal standard For all analysis types, users
instruments. Designed for ease-of-use, the can select one bead for the intra-well normalization bead.
software allows the novice and advanced user Allelic ratios and allele call graphing function Allele call analysis with new bar
alike, to set up and run an assay in a minimal and line charts are now available for the analysis of allelic ratio data.
amount of time. Notification, alert options and remote monitoring Users can log on remotely to
monitor the system status. The software can also be configured to send out email
The softwares graphical user interface follows notifications when an assay has been completed or if the system has encountered
the typical assay workflow but can be customized a problem.
to meet the needs of a specific laboratory. Low bead count detection The software can be configured to alert the user if a
Navigation wizards and automated routine user-defined number of successive wells do not reach the minimum bead count.
operations such as startup, shutdown, calibration On-the-fly regression analysis capability Enables the user to quickly and easily
and performance verification, further enhance reanalyze batch data with alternate curve fit algorithms.
system usability and reduced hands-on-time. Luminex or third-party data analysis programs The user can select from a user-
defined set of analysis programs when setting up a protocol and the software will
automatically launch the program once the data acquisition has been completed.

15
xPONENT Software Solutions

xPONENT Workflow

Easy to use xPONENT Software Software for MAGPIX & FLEXMAP 3D


Software

is designed with intuitive navigation


Description Part Numbers
tabs and simplified workflow. Novice
xPONENT 4.2 Upgrade Kit XPON4.2-UPGRADE-KITS
and advanced users alike can set up
xPONENT 4.2 for 21 CFR Part 11 Module XPON4.2-21CFR
and run an assay in a minimal amount
xPONENT 4.2 Allele Call Module XPON4.2-ALLELE
of time.
xPONENT 4.2 Automation Module XPON4.2-AUTO
xPONENT 4.2 LIS Module XPON4.2-LIS
xPONENT 4.2 Extra Seat Module XPON4.2-SEATS
xPONENT 4.2 Security Module XPON4.2-SECURITY
xPONENT 4.2 Remote Web Monitor Module XPON4.2-REMWEBMON
Reduced hands-on time Navigation
wizards and automated routine
operations such as startup, shutdown, Software for Luminex 200
calibration, performance verification
Description Part Numbers
and analysis enhance system usability
xPONENT 3.1 Upgrade Kit XPON3.1-UPGRADE-KITS
and reduce hands-on time.
xPONENT 3.1 Rev 2 - 21 CFR Part 11 Module XPON3.1R2-21CFR
xPONENT 3.1 Rev 2 Allele Call Module XPON3.1R2-ALLELE
xPONENT 3.1 Rev 2 Automation Module XPON3.1R2-AUTO
xPONENT 3.1 Rev 2 LIS Module XPON3.1R2-LIS-MOD
Customizable - The graphical user xPONENT 3.1 Rev 2 Extra Seats XPON3.1R2-SEATS

interface follows the typical assay xPONENT 3.1 Rev 2 Security Module XPON3.1R2-SECURITY
xPONENT 3.1 Rev 2 Remote Web Monitoring Module XPON3.1R2-WEBMON
workflow but a modular architecture
allows configuration to meet the
needs of a specific laboratory.

16
xPONENT Software Options

xPONENT Software is available with three levels of accessibility:

Basic

Software
The basic xPONENT software package allows the user to acquire samples, perform analysis, run system maintenance routines and remote
web monitoring. This package includes the ability to calculate allelic ratios to analyze and/or normalize genotyping data.Three seat licenses are
included with every copy of xPONENT software, but additional seat licenses are available.*

Secure*
The secure xPONENT package includes all the basic functionality, and allows an administrator to set up user access levels.

21 CFR Part 11*


For laboratories working under the FDAs 21 CFR part 11 regulations, xPONENT offers multilevel user management, full audit trail, electronic
records and electronic signatures.

xPONENT Software offers two additional licensed modules:

Automation Connectivity*
The automation module, along with a device driver, enables communication between the reader and a front end automation platform. Luminex
device drivers are offered by many automation providers. For more information on available drivers please contact Luminex Technical Support.*

LIS Connectivity*
The LIS connectivity module allows communication with an external Laboratory Information System (LIS) by allowing the export of patient
result data and the import of patient sample information in ASTM format. Connection to your LIS may require the use of middleware. For more
information on LIS and middleware solutions please contact Luminex Technical Support.

*Additional costs may apply. Contact Luminex for more details and pricing. See contact information on page 41.
17
Luminex
Reagents

100/200 System
and Accessories

Reagents

18
Reagents and Accessories

Microspheres
xMAP Technology uses color-coded microspheres (beads) to test for multiple targets from a single sample. Depending on the Luminex
instrument, the application, and the analytes of interest, there are different bead types that can be used to produce the best results:

Application Microsphere Type Regions Available Concentrations Available Vial Sizes Available
(million beads/mL)
All Purpose MagPlex Magnetic 1-500 2.5 (10 regions only) & 12.5 1mL, 4mL, Custom*
MicroPlex Non-Magnetic 1-100 12.5 1mL, 4mL, 16mL
Nucleic Acid MagPlex-TAG Magnetic 1-150 2.5 1mL

Reagents
Protein LumAvidin Non-Magnetic 1-100 2.5 1mL
SeroMAP Non-Magnetic 1-100 12.5 4mL

*Please see the MagPlex Custom Volume Ordering Guidelines online or contact Luminex to inquire about custom volume options.

Microsphere Shelf-Life: The shelf-life of a xMAP microspheres is the length of time after manufacturing during which a microsphere should
be used for coupling to a capture molecule. After coupling, microsphere stability will vary depending on a variety of customer-defined factors
(molecule, buffer and storage temperature, etc.). Luminex recommends that customers verify the stability of coupled microspheres in their own
lab under their own conditions.

Other Reagents & Accessories


Instrument Reagents - xMAP instrument reagents include sheath fluid, drive fluid and instrument calibration and verification kits.
Assay Development Reagents - The first in a new line of assay development reagents is the xMAP Antibody Coupling (AbC) Kit.
Accessories - For MagPlex assays, the magnetic plate separator and tube separator enable fast and easy washing of beads.
Reagent Lead Times: Most reagents ship within three days of order receipt.

19
MagPlex
LuminexMicrospheres
100/200 System

Luminexs magnetic carboxylated microspheres Key MagPlex Microspheres Features


offer improved washing efficiency and
Surface carboxyl groups
multiplexing up to 500-plex, compatible with
Superparamagnetic
all xMAP instruments. Similar to MicroPlex
500 regions available
Microspheres, MagPlex Microspheres are
Compatible with all xMAP instruments
carboxylated polystyrene micro-particles, or
Multiple vial sizes available
beads, that have been dyed into spectrally
Multiple concentrations available
distinct sets, or regions, allowing them to be
individually identified by an xMAP Instrument.
These uniquely coded beads provide a user MagPlex Microspheres Benefits
an addressable substrate on which to perform
Reagents

Same reliable coupling chemistry as MicroPlex


multiple bio-analytical reactions in a single well. 5x increased multiplex capability
Dramatically improved washing efficiency
All microspheres are general use components Ideal for automated applications
for further manufacture of xMAP bioassays. No need for expensive filter plates
MagPlex Microspheres are available at Available in low concentration for small scale and assay development applications
concentrations of 2.5 million and 12.5 million
Vial Size Concentration # of Regions Available Part Numbers
beads/mL and can be ordered in 1mL and 4mL (millions/mL)
vial sizes. MagPlex Microspheres are also
1 mL 2.5 10 MC100XX-ID
offered in a variety of custom volumes. Please
1 mL 12.5 500 MC1XXXX-01
see the MagPlex Custom Volume Ordering
4 mL 12.5 80 MC10XXX-04
Guidelines online or contact Luminex to inquire
about custom volume options.
IMPORTANT: MagPlex Microspheres require the use of xPONENT Software.

20
MagPlexLuminex
Microspheres Part Numbers
100/200 System

Group A (50) Group B (30) Group C (420)


500 MagPlex Regions Available All xMAP Instruments LX100/200 & FLEXMAP 3D FLEXMAP 3D Only
Reg. Part # Reg. Part # Reg. Part # Reg. Part # Reg. Part Number
12 MC10012-YY 45 MC10045-YY 7 MC10007-YY 85 MC10085-YY 1 MC12001-01

Available in Low Concentration


13 MC10013-YY 46 MC10046-YY 8 MC10008-YY 86 MC10086-YY 2 MC12002-01
14 MC10014-YY 47 MC10047-YY 9 MC10009-YY 87 MC10087-YY 3 MC12003-01
15 MC10015-YY 48 MC10048-YY 49 MC10049-YY 88 MC10088-YY 4 MC12004-01
18 MC10018-YY 51 MC10051-YY 58 MC10058-YY 89 MC10089-YY 5 MC12005-01
19 MC10019-YY 52 MC10052-YY 59 MC10059-YY 90 MC10090-YY 6 MC12006-01
20 MC10020-YY 53 MC10053-YY 68 MC10068-YY 91 MC10091-YY 10 MC12010-01
21 MC10021-YY 54 MC10054-YY 69 MC10069-YY 93 MC10093-YY 11 MC12011-01
22 MC10022-YY 55 MC10055-YY 70 MC10070-YY 94 MC10094-YY 16 MC12016-01

Reagents
25 MC10025-YY 56 MC10056-YY 79 MC10079-YY 95 MC10095-YY 17 MC12017-01
26 MC10026-YY 57 MC10057-YY 80 MC10080-YY 96 MC10096-YY 23 MC12023-01
27 MC10027-YY 61 MC10061-YY 81 MC10081-YY 97 MC10097-YY 24 MC12024-01
101500 28 MC10028-YY 62 MC10062-YY 82 MC10082-YY 98 MC10098-YY 31 MC12031-01
Compatible with: 29 MC10029-YY 63 MC10063-YY 83 MC10083-YY 99 MC10099-YY 32 MC12032-01
All xMAP Instruments 30 MC10030-YY 64 MC10064-YY 84 MC10084-YY 100 MC10100-YY 40 MC12040-01
Luminex 100/200 & FLEXMAP 3D 33 MC10033-YY 65 MC10065-YY 41 MC12041-01
FLEXMAP 3D Only
34 MC10034-YY 66 MC10066-YY Vial Sizes:  [-YY] = [-01] for 1mL, [-04] 50 MC12050-01
35 MC10035-YY 67 MC10067-YY for 4mL, or [-ID] for 1mL Low 60 MC12060-01
36 MC10036-YY 72 MC10072-YY Concentration. 71 MC12071-01
Shelf Life: MagPlex Microspheres have a maximum shelf-
life of 5 years from the date of manufacture. All MagPlex 37 MC10037-YY 73 MC10073-YY NOTE: Group C regions are only 92 MC12092-01
Microspheres are guaranteed to have a minimum remaining
38 MC10038-YY 74 MC10074-YY available in 1mL vial sizes. 101+ MC10XXX-01
shelf life from the date they ship. Group A & Group B regions Contact Luminex to inquire
have a minimum shelf-life of 6 months from the date of 39 MC10039-YY 75 MC10075-YY
about custom fill options. [XXX] = region # >100
shipment and Group C regions have a minimum shelf-life of 3
42 MC10042-YY 76 MC10076-YY
months from the ship date. NOTE: Group C regions <100 have
43 MC10043-YY 77 MC10077-YY
MC12XXX catalog numbers.
44 MC10044-YY 78 MC10078-YY

21
MagPlex-TAG Microspheres
Luminex 100/200 System

MagPlex-TAG Microspheres are oligonucleotide- MagPlex-TAG Microspheres Features


coupled polystyrene micro-particles, or beads,
150 Unique 24mer surface anti-TAG DNA sequences
that have been dyed into spectrally distinct sets,
150 Regions available (each with unique anti-TAG)*
or regions; allowing them to be individually
Compatible with all xMAP Instruments
identified by an xMAP Instrument.
1mL vial size
2.5 million beads/mL concentration
Each one of these uniquely color-coded beads
has a unique 24 base DNA sequence, called an
anti-TAG, covalently coupled to its surface. MagPlex-TAG Microspheres Benefits
These beads enable the user to quickly and Eliminate the need to couple oligonucleotides to beads
easily design custom bead arrays, simply by
Reagents

Proven xTAG technology


adding a complementary TAG sequence Increased multiplex capability
to their primers or probes of interest and Improved washing efficiency
hybridizing those primers or probes to the anti- Ideal for automated applications
TAG sequence on the addressable microsphere. No need for expensive filter plates
Convenient 2.5 million bead/mL concentration for improved handling
For a complete list of the TAG and anti-TAG
sequences for each of the 150 available Vial Size Concentration # of Regions Available Part Numbers
(millions/mL)
microspheres, visit www.luminexcorp.com.
1 mL 2.5 150 MTAG-XXXX

IMPORTANT: MagPlex-TAG Microspheres require the use of xPONENT Software.

*MagPlex-TAG Group C regions are built-to-order. Please contact your Luminex representative to inquire about minimum order requirements and lead times for these regions.
22
MagPlex-TAGLuminex
Microspheres Part Numbers
100/200 System

Group A (50) Group B (30) Group C (70)*


150 MagPlex-TAG Regions Available* All xMAP Instruments LX100/200 & FLEXMAP 3D FLEXMAP 3D Only
Reg. Part # Reg. Part # Reg. Part # Reg. Part # Reg. Part Number
12 MTAG-A012 45 MTAG-A045 7 MTAG-B007 85 MTAG-B085 1 MTAG-C001
13 MTAG-A013 46 MTAG-A046 8 MTAG-B008 86 MTAG-B086 2 MTAG-C002
14 MTAG-A014 47 MTAG-A047 9 MTAG-B009 87 MTAG-B087 3 MTAG-C003
15 MTAG-A015 48 MTAG-A048 49 MTAG-B049 88 MTAG-B088 4 MTAG-C004
18 MTAG-A018 51 MTAG-A051 58 MTAG-B058 89 MTAG-B089 5 MTAG-C005
19 MTAG-A019 52 MTAG-A052 59 MTAG-B059 90 MTAG-B090 6 MTAG-C006
20 MTAG-A020 53 MTAG-A053 68 MTAG-B068 91 MTAG-B091 10 MTAG-C010
21 MTAG-A021 54 MTAG-A054 69 MTAG-B069 93 MTAG-B093 11 MTAG-C011
22 MTAG-A022 55 MTAG-A055 70 MTAG-B070 94 MTAG-B094 16 MTAG-C016

Reagents
25 MTAG-A025 56 MTAG-A056 79 MTAG-B079 95 MTAG-B095 17 MTAG-C017
26 MTAG-A026 57 MTAG-A057 80 MTAG-B080 96 MTAG-B096 23 MTAG-C023
27 MTAG-A027 61 MTAG-A061 81 MTAG-B081 97 MTAG-B097 24 MTAG-C024
101150
28 MTAG-A028 62 MTAG-A062 82 MTAG-B082 98 MTAG-B098 31 MTAG-C031
Compatible with: 29 MTAG-A029 63 MTAG-A063 83 MTAG-B083 99 MTAG-B099 32 MTAG-C032
All xMAP Instruments 30 MTAG-A030 64 MTAG-A064 84 MTAG-B084 100 MTAG-B100 40 MTAG-C040
Luminex 100/200 & FLEXMAP 3D 33 MTAG-A033 65 MTAG-A065 41 MTAG-C041
FLEXMAP 3D Only
34 MTAG-A034 66 MTAG-A066 50 MTAG-C050
*Contact Luminex if additional regions are required Available in 1mL vial sizes only.
35 MTAG-A035 67 MTAG-A067 60 MTAG-C060
36 MTAG-A036 72 MTAG-A072 Contact Luminex to inquire about 71 MTAG-C071
Shelf Life: MagPlex-TAG Microspheres have a maximum custom fill options.
shelf-life of 2 years from the date of manufacture. All 37 MTAG-A037 73 MTAG-A073 92 MTAG-C092
MagPlex-TAG Microspheres are guaranteed to have a 38 MTAG-A038 74 MTAG-A074 Refer to Product Information Sheet 101+ MTAG-CXXX
minimum remaining shelf life from the date they ship. Group (Doc# 89-30000-00-265) for the anti-
A & Group B regions have a minimum shelf-life of 6 months
39 MTAG-A039 75 MTAG-A075
TAG sequences of each region. [XXX] = region # >100
from the date of shipment and Group C regions have a 42 MTAG-A042 76 MTAG-A076
minimum shelf-life of 3 months from the ship date.
43 MTAG-A043 77 MTAG-A077
44 MTAG-A044 78 MTAG-A078

*MagPlex-TAG Group C regions are built-to-order. Please contact your Luminex representative to inquire about minimum order requirements and lead times for these regions.
23
MicroPlex Microspheres

MicroPlex Microspheres are carboxylated Key MicroPlex Microspheres Features


polystyrene micro-particles that have been
Surface carboxyl groups
color coded into 100 spectrally distinct
100 Regions available
sets or regions.
Compatible with Luminex 100/200 and FLEXMAP 3D
Compatible with IS 2.3 and xPONENT Software
Each of these microsphere, or bead, regions
Multiple vial sizes available
can be quickly distinguished by an xMAP
Available at 12.5 million beads/mL concentration
Instrument allowing for the interrogation of up
to 100 different analytes, simultaneously, from
one single sample volume. MicroPlex Microspheres Benefits
Reagents

Proven reliability
All microspheres are general use components Suitable for both protein and nucleic acid applications
for further manufacture of xMAP bioassays. Convenient vial sizes for all scales of work

MicroPlex Microspheres are available at a Vial Size Concentration # of Regions Available Part Number(s)
(million/mL)
concentration of 12.5 million beads/mL and can
1mL 12.5 100 LC10XXX-01
be ordered in 1mL, 4mL, and 16mL vial sizes.
4mL 12.5 100 LC10XXX-04

Please contact Luminex to inquire about custom 16mL 12.5 100 LC10XXX-16

volume options.
IMPORTANT: MicroPlex Microspheres are not compatible with the MAGPIX Instrument.

24
MicroPlex Microspheres Part Numbers

100 MicroPlex Regions Available Reg. Part Number Reg. Part Number Reg. Part Number Reg. Part Number Reg. Part Number
1 LC10001-YY 22 LC10022-YY 43 LC10043-YY 64 LC10064-YY 85 LC10085-YY

2 LC10002-YY 23 LC10023-YY 44 LC10044-YY 65 LC10065-YY 86 LC10086-YY

3 LC10003-YY 24 LC10024-YY 45 LC10045-YY 66 LC10066-YY 87 LC10087-YY

4 LC10004-YY 25 LC10025-YY 46 LC10046-YY 67 LC10067-YY 88 LC10088-YY

5 LC10005-YY 26 LC10026-YY 47 LC10047-YY 68 LC10068-YY 89 LC10089-YY

6 LC10006-YY 27 LC10027-YY 48 LC10048-YY 69 LC10069-YY 90 LC10090-YY

7 LC10007-YY 28 LC10028-YY 49 LC10049-YY 70 LC10070-YY 91 LC10091-YY

8 LC10008-YY 29 LC10029-YY 50 LC10050-YY 71 LC10071-YY 92 LC10092-YY

Reagents
9 LC10009-YY 30 LC10030-YY 51 LC10051-YY 72 LC10072-YY 93 LC10093-YY

10 LC10010-YY 31 LC10031-YY 52 LC10052-YY 73 LC10073-YY 94 LC10094-YY

11 LC10011-YY 32 LC10032-YY 53 LC10053-YY 74 LC10074-YY 95 LC10095-YY

12 LC10012-YY 33 LC10033-YY 54 LC10054-YY 75 LC10075-YY 96 LC10096-YY


Compatible with:
13 LC10013-YY 34 LC10034-YY 55 LC10055-YY 76 LC10076-YY 97 LC10097-YY
Luminex 100/200 & FLEXMAP 3D
14 LC10014-YY 35 LC10035-YY 56 LC10056-YY 77 LC10077-YY 98 LC10098-YY

15 LC10015-YY 36 LC10036-YY 57 LC10057-YY 78 LC10078-YY 99 LC10099-YY


Shelf Life: MicroPlex Microspheres have a maximum shelf-
16 LC10016-YY 37 LC10037-YY 58 LC10058-YY 79 LC10079-YY 100 LC10100-YY
life of 5 years from the date of manufacture. All MicroPlex
Microspheres are guaranteed to have a minimum remaining 17 LC10017-YY 38 LC10038-YY 59 LC10059-YY 80 LC10080-YY
shelf life of 6 months from the date they ship. Vial Sizes:
18 LC10018-YY 39 LC10039-YY 60 LC10060-YY 81 LC10081-YY
[-YY] = [-01] for 1mL;
19 LC10019-YY 40 LC10040-YY 61 LC10061-YY 82 LC10082-YY [-04] for 4mL; or
20 LC10020-YY 41 LC10041-YY 62 LC10062-YY 83 LC10083-YY [-16] for 16mL

21 LC10021-YY 42 LC10042-YY 63 LC10063-YY 84 LC10084-YY

25
LumAvidin Microspheres

LumAvidin Microspheres are avidin-coupled Key LumAvidin Microspheres Features


polystyrene micro-particles that have been
Avidin protein coated surface
color coded into 100 spectrally distinct sets or
100 Regions available
regions. Similar to an avidin-coated ELISA plate,
Compatible with Luminex 100/200 and FLEXMAP 3D
when reacted with a biotinylated ligand, such as
1mL vial size
a peptide, each of these beads can be used as the
2.5 million bead/mL concentration
substrate on which an assay can be performed.
Because each of the beads is uniquely color-
coded, they can be quickly distinguished by an LumAvidin Microspheres Benefits
xMAP Instrument allowing for the interrogation Near-covalent biotin-binding chemistry
of up to 100 different analytes simultaneously
Reagents

Ideal for coupling small molecules, like biotinylated peptides


from one single sample volume. Suitable for protein and immunogenicity applications
Convenient concentration for improved handling
All microspheres are general use components
for further manufacture of xMAP bioassays. Vial Size Concentration # of Regions Available Part Numbers
(millions/mL)
LumAvidin Microspheres are available at a
1 mL 2.5 100 L100-LXXX-01
concentration of 2.5 million beads/mL and can
be ordered in 1mL vial sizes only. Please contact
Luminex to inquire about custom vial sizes. IMPORTANT: LumAvidin Microspheres are not compatible with the MAGPIX Instrument.

26
LumAvidin Microspheres Part Numbers

100 LumAvidin Regions Available Reg. Part Number Reg. Part Number Reg. Part Number Reg. Part Number Reg. Part Number
1 L100-L101-01 22 L100-L122-01 43 L100-L143-01 64 L100-L164-01 85 L100-L185-01

2 L100-L102-01 23 L100-L123-01 44 L100-L144-01 65 L100-L165-01 86 L100-L186-01

3 L100-L103-01 24 L100-L124-01 45 L100-L145-01 66 L100-L166-01 87 L100-L187-01

4 L100-L104-01 25 L100-L125-01 46 L100-L146-01 67 L100-L167-01 88 L100-L188-01

5 L100-L105-01 26 L100-L126-01 47 L100-L147-01 68 L100-L168-01 89 L100-L189-01

6 L100-L106-01 27 L100-L127-01 48 L100-L148-01 69 L100-L169-01 90 L100-L190-01

7 L100-L107-01 28 L100-L128-01 49 L100-L149-01 70 L100-L170-01 91 L100-L191-01

8 L100-L108-01 29 L100-L129-01 50 L100-L150-01 71 L100-L171-01 92 L100-L192-01

Reagents
9 L100-L109-01 30 L100-L130-01 51 L100-L151-01 72 L100-L172-01 93 L100-L193-01

10 L100-L110-01 31 L100-L131-01 52 L100-L152-01 73 L100-L173-01 94 L100-L194-01

11 L100-L111-01 32 L100-L132-01 53 L100-L153-01 74 L100-L174-01 95 L100-L195-01

12 L100-L112-01 33 L100-L133-01 54 L100-L154-01 75 L100-L175-01 96 L100-L196-01


Compatible with:
13 L100-L113-01 34 L100-L134-01 55 L100-L155-01 76 L100-L176-01 97 L100-L197-01
Luminex 100/200 & FLEXMAP 3D
14 L100-L114-01 35 L100-L135-01 56 L100-L156-01 77 L100-L177-01 98 L100-L198-01

15 L100-L115-01 36 L100-L136-01 57 L100-L157-01 78 L100-L178-01 99 L100-L199-01


Shelf Life: LumAvidin Microspheres have a maximum shelf-
16 L100-L116-01 37 L100-L137-01 58 L100-L158-01 79 L100-L179-01 100 L100-L200-01
life of 1 year from the date of manufacture. All LumAvidin
Microspheres are guaranteed to have a minimum remaining 17 L100-L117-01 38 L100-L138-01 59 L100-L159-01 80 L100-L180-01
shelf life of 3 months from the date they ship. Only available in 1mL
18 L100-L118-01 39 L100-L139-01 60 L100-L160-01 81 L100-L181-01
vial sizes.
19 L100-L119-01 40 L100-L140-01 61 L100-L161-01 82 L100-L182-01 Contact Luminex to
inquire about custom
20 L100-L120-01 41 L100-L141-01 62 L100-L162-01 83 L100-L183-01
fill options.
21 L100-L121-01 42 L100-L142-01 63 L100-L163-01 84 L100-L184-01

27
SeroMAP Microspheres

SeroMAP Microspheres are a special Key SeroMAP Microspheres Features


formulation of MicroPlex Microspheres, which
Specifically designed for protein-based serological applications
have been optimized to reduce non-specific
100 Regions available
binding in serology assays. These beads are
Compatible with Luminex 100/200 and FLEXMAP 3D
carboxylated polystyrene micro-particles that
4mL vial size only
have been color coded into 100 spectrally
12.5 million bead/mL concentration
distinct sets or regions. Each of these regions
can be quickly distinguished by an xMAP
Instrument allowing for the interrogation of up SeroMAP Microspheres Benefits
to 100 different analytes simultaneously from Same low price as MicroPlex Microspheres
one single sample volume.
Reagents

Lower non-specific binding


Ideal for serology assay applications
All microspheres are general use components
for further manufacture of xMAP bioassays. Vial Size Concentration # of Regions Available Part Numbers
SeroMAP Microspheres are available at a (millions/mL)

concentration of 12.5 million beads/mL and are 4 mL 12.5 100 L100-SXXX-04


only available in a 4mL vial size. Please contact
Luminex to inquire about custom vial sizes. IMPORTANT: SeroMAP Microspheres are not compatible with the MAGPIX Instrument.

28
SeroMAP Microspheres Part Numbers

100 SeroMAP Regions Available Reg. Part Number Reg. Part Number Reg. Part Number Reg. Part Number Reg. Part Number
1 L100-S001-04 22 L100-S022-04 43 L100-S043-04 64 L100-S064-04 85 L100-S085-04

2 L100-S002-04 23 L100-S023-04 44 L100-S044-04 65 L100-S065-04 86 L100-S086-04

3 L100-S003-04 24 L100-S024-04 45 L100-S045-04 66 L100-S066-04 87 L100-S087-04

4 L100-S004-04 25 L100-S025-04 46 L100-S046-04 67 L100-S067-04 88 L100-S088-04

5 L100-S005-04 26 L100-S026-04 47 L100-S047-04 68 L100-S068-04 89 L100-S089-04

6 L100-S006-04 27 L100-S027-04 48 L100-S048-04 69 L100-S069-04 90 L100-S090-04

7 L100-S007-04 28 L100-S028-04 49 L100-S049-04 70 L100-S070-04 91 L100-S091-04

8 L100-S008-04 29 L100-S029-04 50 L100-S050-04 71 L100-S071-04 92 L100-S092-04

Reagents
9 L100-S009-04 30 L100-S030-04 51 L100-S051-04 72 L100-S072-04 93 L100-S093-04

10 L100-S010-04 31 L100-S031-04 52 L100-S052-04 73 L100-S073-04 94 L100-S094-04

11 L100-S011-04 32 L100-S032-04 53 L100-S053-04 74 L100-S074-04 95 L100-S095-04

12 L100-S012-04 33 L100-S033-04 54 L100-S054-04 75 L100-S075-04 96 L100-S096-04


Compatible with:
13 L100-S013-04 34 L100-S034-04 55 L100-S055-04 76 L100-S076-04 97 L100-S097-04
Luminex 100/200 & FLEXMAP 3D
14 L100-S014-04 35 L100-S035-04 56 L100-S056-04 77 L100-S077-04 98 L100-S098-04

15 L100-S015-04 36 L100-S036-04 57 L100-S057-04 78 L100-S078-04 99 L100-S099-04


Shelf Life: SeroMAP Microspheres have a maximum shelf-
16 L100-S016-04 37 L100-S037-04 58 L100-S058-04 79 L100-S079-04 100 L100-S100-04
life of 3 years from the date of manufacture. All SeroMAP
Microspheres are guaranteed to have a minimum remaining 17 L100-S017-04 38 L100-S038-04 59 L100-S059-04 80 L100-S080-04
shelf life of 6 months from the date they ship. Only available in 4mL
18 L100-S018-04 39 L100-S039-04 60 L100-S060-04 81 L100-S081-04
vial sizes.
19 L100-S019-04 40 L100-S040-04 61 L100-S061-04 82 L100-S082-04 Contact Luminex to
inquire about custom
20 L100-S020-04 41 L100-S041-04 62 L100-S062-04 83 L100-S083-04
fill options.
21 L100-S021-04 42 L100-S042-04 63 L100-S063-04 84 L100-S084-04

29
xMAP Instrument Reagents

MAGPIX Reagents Luminex 100/200 Reagents FLEXMAP 3D Reagents

The MAGPIX instrument requires drive The Luminex 100 and Luminex 200 The FLEXMAP 3D instrument requires sheath
Reagents

fluid to serve as the delivery medium to instruments require sheath fluid to serve as fluid to serve as the delivery medium to
transport the beads to the instruments the delivery medium to transport the beads transport the beads to the instruments optics.
optics. Due to the compact nature of the to the instruments optics. Both instruments
MAGPIX system, drive fluid is available in have the option of a 20L disposable external This instrument has the option of a 20L
small pre-filled disposable containers which sheath fluid container or a compact 20X disposable external sheath fluid container
are stored within the instrument. Each drive sheath fluid concentrate pack; which can or a compact 20X sheath fluid concentrate
fluid container provides enough fluid to read be reconstituted, with water, to a working pack; which can be reconstituted, with water,
approximately ten plates of samples, and volume of 20L when needed. The Luminex to a working volume of 20L when needed.
they are sold in packages of four. MAGPIX 100/200 instruments, operating on The FLEXMAP 3D instrument is calibrated
uses a calibration kit and a verification kit, xPONENT software, are calibrated using using a calibration and a verification kit, each
each providing 25 uses. a calibration and a verification kit, each providing 25 uses.
providing 25 uses. Luminex systems running
on the older IS 2.3 software require the
purchase of individual vials of calibration and
control microspheres.

30
xMAP Instrument Reagents

Instrument Reagent Pack Size Part Number


MAGPIX MAGPIX Drive Fluid 4 pack MPXDF-4PK
MAGPIX Calibration Kit 25 uses MPX-CAL-K25
MAGPIX Performance Verification Kit 25 uses MPX-PVER-K25
Luminex 100/200 (all versions) Sheath Fluid 20L 40-50000
Sheath Concentrate Pack (20x) 1L 40-75680
Luminex 100/200 (xPONENT only) Luminex 100/200 Calibration Kit 25 uses LX200-CAL-K25
Luminex 100/200 Performance Verification Kit 25 uses LX200-CON-K25
Luminex 100/200 (IS 2.3 only) Luminex 100/200 Classification Calibration 5mL L100-CAL1

Reagents
Microspheres
Luminex 100/200 Reporter Calibration 5mL L100-CAL2
Microspheres
Luminex 100/200 Classification Control 5mL L100-CON1
Microspheres
Luminex 100/200 Reporter Control Microspheres 5mL L100-CON2
FLEXMAP 3D Sheath Fluid 20L 40-50000
Sheath Concentrate Pack (20x) 1L 40-75680
FLEXMAP 3D Calibration Kit 25 uses F3D-CAL-K25
FLEXMAP 3D Performance Verification Kit 25 uses F3D-PVER-K25

Shelf-life: Sheath Fluid (20L) and Drive Fluid have a 2 year shelf-life, from the data of manufacture, and Luminex guarantees a shelf-life of no less than 6 months from
the shipment date. Sheath Concentrate Pack (1L) has a 9 month shelf-life, from the date of manufacture, and a guaranteed 3 month minimum shelf-life. Calibration and
Verification reagents all have a 2 year shelf-life and a guaranteed 6 month minimum shelf-life from the shipment date.
31
xMAP Antibody Coupling (AbC) Kit

xMAP Antibody Coupling Kit Features:


Pre-optimized reagents and buffers (including EDC)
All required consumables (i.e., reaction tubes, pipettes)
Easy-to-use protocol

Other Specifications:
Run Times
Hands-on time = ~40mins
Total turn-around time = ~3hrs
Reagents

Kit Capacity
Small scale: up to 10 reactions of 5x106 beads/reaction or less
Large scale: up to 4 reactions of greater then 5x106
The xMAP Antibody Coupling Kit, or AbC kit, is a reagent kit
beads/reaction
that contains everything a researcher needs to couple an antibody
Maximum scale is 12.5x106 beads/reaction
to MagPlex Microspheres. Similar to an ELISA plate, MagPlex
Microspheres can be used as the substrate on which immunoassays can Number of Beads That Can Be Coupled Per Kit
be performed. Unlike a traditional ELISA, however, this assay method Maximum: 50x106 beads (4 reactions @ 12.5x106 beads/reaction)
requires much less antibody, sample, and time; with equal or better Minimum: 2.5x106 beads (1 reaction @ 2.5x106 beads/reaction)
sensitivity and dynamic range. Since each microsphere is uniquely Product Part Numbers
addressable, multiple immunoassays can be performed simultaneously xMAP AbC Kit 40-50016
with the same sample, in the same well. Once your desired antibody is
coupled to the surface of the bead you can begin optimizing monoplex Shelf-life: This kit has a shelf-life of 1 year from the date of
or multiplex capture-sandwich immunoassays to suit your needs. manufacture. All xMAP AbC kits are guaranteed to have a
minimum remaining shelf life of 1 month from the date they ship.
NOTE: This kit does NOT include microspheres or antibodies.

For more information on how xMAP stacks up against ELISA download the xMAP vs. ELISA White Paper from luminexcorp.com.
32
Magnetic Separators

Magnetic Plate Separator Magnetic Plate Separator Highlights:


The Luminex Magnetic Plate Separator For use in nucleic acid and protein assay preparation
is a modified plate magnet intended to Designed to be used with the Manual Washing Procedure
separate a 96-well plate of MagPlex for MagPlex Microspheres
Microspheres during assay preparation ~ 90% less expensive than a typical automated plate
steps. The side clasps on this magnet washer
have been specially designed to hold Allows customers to use the familiar washing technique
a round-bottom plate securely to the they have used for ELISA
magnet, enabling the user to quickly invert and decant it over a waste
container. Similar to the method used in an ELISA, this manual plate

Reagents
washing method has been shown to effectively remove nearly all of the
supernatant from every well on the plate, with virtually no bead carry-over.

Magnetic Tube Separator Magnetic Tube Separator Highlights:


The Luminex 1.5mL Tube Magnetic For use in bead coupling and single reaction nucleic acid
Separator is intended for a single and protein assay preparation
reaction tube. Typically used in bead Ideal for small scale coupling reactions
coupling reactions, this magnet
can quickly separate 1mL MagPlex
Product Part Numbers
Microspheres from solution and is a
handy addition to any xMAP bench top. Magnetic Plate Separator CN-0269-01
Magnetic Tube Separator CN-0288-01

33
Instrument Service Plans

Luminex 200, FLEXMAP 3D, and MAGPIX (North America, Europe, Japan, and China*)
Luminex 200 & FLEXMAP 3D MAGPIX Only

Platinum Platinum Gold 360 Gold Silver** Bronze** Platinum Gold Standard
360*
Number of visits for emergency Unlimited Unlimited Unlimited Unlimited Unlimited None Unlimited Unlimited Unlimited
repair
Emergency repair costs included All Costs All Costs All Costs All Costs Travel & 20% All Costs All Costs All Costs
in plan Included Included Included Included Labor only discount off Included Included Included
Parts only
Preventative maintenance visits Two Two One One One One Two One None
per year
On-site response time (business One One Two Two Two, after None One Two Two
days) receipt of PO Guaranteed
Priority scheduling for service Included Included Included Included Included None Included Included Included
requests
Product updates and hardware Included Included Included Included Included None Included Included Included
modifications
Software support Included Included Included Included Included None Included Included Included
Service

Unlimited 24x7x365 remote Included Included Included Included Included Included Included Included Included
support (Unlimited, during
business hours -
Japan)

On-site assay support, as needed Included Not Included Included Not Included Not Included Not Included Not Included Not Included Not Included
(Luminex Assays Only)
Part Number SLA- SLA- SLA- SLA-Gold or SLA-Silver SLA-Bronze SLA- SLA- SLA-
Platinum360 Platinum Gold360 Japan Gold MAGPIX- MAGPIX- MAGPIX-
Plat-PM Gold-PM Gold-Std
* Not all service plans are available in all countries. See the chart on next page for plan coverage.
** Bronze and Silver packages are not available for MAGPIX.

34
Instrument Service Plans

Supported Countries
Countries Platinum Platinum Gold Gold Silver Bronze Countries Platinum Platinum Gold Gold Silver Bronze
360 360 360 360
Austria Jamaica
Bahamas Japan
Barbados Latvia
Belgium Lithuania
Bermuda Luxembourg
Bulgaria Malta
Canada Mexico
Cayman Islands Monaco
China Netherlands
Croatia Norway
Cyprus Poland
Czech Republic Portugal
Denmark Puerto Rico
Dominican Republic Romania

Service
Estonia Slovakia
Finland Slovenia
France Spain
Germany Sweden
Greece Switzerland
Hong Kong United Kingdom
Hungary United States
Iceland Virgin Islands (British)
Ireland Virgin Islands (U.S.)
Italy

35
Luminex Learning

Explore Courses with Luminex Learning


Luminex offers path-based learning. Each path includes
options for:
Online Training self-paced, online presentations,
simulations and videos
Live-online Training live training conducted in a remote
environment, utilizing a dynamic online meeting tool
Classroom Training face-to-face training either at a
Luminex Learning facility or at a customer site

Each course has clearly stated learning objectives found


online at learning.luminexcorp.com.

Luminex also offers how-to videos to optimize the use


of your Luminex Instrument, which can be found on the
support tab of each of the instrument product pages at
www.luminexcorp.com.
Training with Luminex
Luminex offers standard and customized training courses to enhance These how-to videos include solutions to items such as
your technical knowledge and optimize the use of your Luminex sample probe height adjustment, clog removal, maintenance
Instrument. Luminex Learning courses offer basic and advanced schedules and much more. Luminex is approved as a
continuing education on Luminex technologies and products. These provider of continuing education programs in the clinical
path-based courses offer the fundamental skills needed to operate laboratory sciences by the ASCLS P.A.C.E. Program.
the software and instrument and to develop, optimize and troubleshoot
your own assays and instrument.
Training

36
Luminex Learning Course Offerings

MAGPIX Training Path Course Titles Format Duration Level Part Number
MAGPIX Hardware Installation Online 20 minutes Pre-requisite CN-0245-01
MAGPIX Technology Online 45 minutes Pre-requisite CN-0266-01
MAGPIX Maintenance Online 26 minutes Pre-requisite CN-0249-01
MAGPIX Support Online 5 minutes Pre-requisite CN-0286-01
xPONENT for MAGPIX Online 60 minutes Pre-requisite CN-0247-01
MAGPIX Troubleshooting Online 7 minutes Pre-requisite CN-0280-01
MAGPIX & xPONENT End-User Live Online Live Online 1/2 day Basic CN-0246-01
MAGPIX & xPONENT End-User Classroom Classroom 1/2 day Basic CN-0248-01
MAGPIX & xPONENT Advanced Classroom 1/2 day Advanced CN-0230-01
Luminex 200 Training Path Course Titles Format Duration Level Part Number
Luminex 200 & xPONENT Online 1 hour Pre-requisite CN-0210-01
Luminex 200 & xPONENT End-User Classroom 1/2 day Basic CN-0211-01
Luminex 200 & xPONENT Advanced* Classroom 1/2 day Advanced CN-0171-01
FLEXMAP 3D Training Path Course Titles Format Duration Level Part Number
FLEXMAP 3D & xPONENT 4.0 Online 1 hour Pre-requisite CN-0205-01
FLEXMAP 3D & xPONENT 4.0 End-User* Classroom 1/2 day Basic CN-0203-01
FLEXMAP 3D & xPONENT 4.2 End-User Classroom 1/2 day Basic CN-0311-01
Customer Developed Assays Training Course Titles Format Duration Level Part Number
Fundamentals of Antibody Coupling Classroom 1/2 day Advanced CN-0347-01
Capture Sandwich Immunoassay Development Classroom 1/2 day Advanced CN-0347-02
Fundamentals of Antigen Coupling Classroom 1/2 day Advanced CN-0347-03
Indirect Immunoassay Development Classroom 1/2 day Advanced CN-0347-04
Nucleic Acid Primer Design Classroom 1 day Advanced CN-0351-01
Direct Hybridization Assay Development Classroom 1 day Advanced CN-0351-02

Training
Allele Specific Primer Extension Assay Development Classroom 1 day Advanced CN-0351-03

* This course is offered at Luminex headquarters in Austin only.


37
Breakthrough Solutions to Improve Health and Advance Science

Luminex Corporation (NASDAQ: LMNX) was Luminex has implemented a unique business strategy, with an engineering focus
incorporated in May 1995 and began commercial on the analyzer itself and a business focus on partnering to rapidly expand the
production of our first generation system in 1997. test menu available to large and growing markets. With more than 60 commercial
Luminex develops, manufactures and markets partners, this market-driven approach has resulted in tests being commercially
innovative biological testing technologies with available in the following areas:
applications throughout the research, diagnostic
and specialty life science industries. Neurodegenerative Disease
Molecular Infectious Disease
The companys open-architecture xMAP Human Genetics Testing
Technology enables large numbers of biological Infectious Disease Testing
tests (bioassays) to be conducted and analyzed Autoimmune Testing
quickly, cost-effectively and accurately. Systems Protein Expression Profiling
using xMAP Technology perform discrete Genomic Research
bioassays on the surface of color-coded beads
known as microspheres, which are then read The open-architecture nature of xMAP Technology means that laboratories and
in a compact analyzer. The technology allows customers can easily develop in-house biological assays to meet their specific
multiple tests to be performed in a single needs. Luminex offers a number of resources to support such home-brew assay
sample (multiplexing), which has many development. To learn about licensing xMAP Technology for commercial assay
scientific and cost advantages over other development, visit www.luminexcorp.com/Partners/BecomeaPartner.
testing platforms.

38
Luminex Partnerships

Luminex licenses xMAP Technology to a variety of partners who develop innovative products and services on this powerful platform.
Partners include the following world-class companies and institutions:

Life Sciences and Diagnostics Diagnostics Wakunaga Pharmaceutical Co. Ltd.


Bio-Rad Laboratories Abbott Laboratories Zeus Scientific
Medical and Biological Laboratories Co. Ltd. Alere
Diagnostic Testing Services
Myriad RBM Asuragen Diagnostics
Perkin Elmer Bayer Healthcare Armune BioScience
PPD Vaccines and Biologics Caris Life Sciences ARUP Laboratories
Celera (Quest Diagnostics) Aviir
Life Sciences DaAn Gene Focus Diagnostics (Quest Diagnostics)
Active Motif DiaMex Laboratory Corporation of America
Affymetrix Diaxonhit Mayo Foundation
EMD/Merck Millipore Immucor Mt. Sinai Medical School
Genometry Ingen Biosciences Prometheus Laboratories
G&G Science Co. Ltd. Innogenetics Quattromed
Green Peptide Co. Ltd. Inova Diagnostics ViraCor-IBT Laboratories
Indicia Biotechnology Interscientific Corporation Animal Diagnostic Testing
INDOOR Biotechnologies Mikrogen Diagnostik
Life Technologies Biovet
Progenika Biopharma (Grifols)
Origene Technologies Charles River Laboratories
Qiagen
Plant Research International Cornell University
Shanghai Tellgen Life Science Co. Ltd.
Protatonce Idexx Laboratories
SureExam
R&D Systems University of California at Davis
Theradiag
Radix Biosolutions One Lambda (Part of Thermo-Fisher Scientific) Biodefense
University of Paris-Sud
Northrop Grumman

All partner names appearing on this page are trademarks owned by those respective companies or institutions. No use of the names on this page may be made
without the prior written authorization of these companies or institutions.
39
Luminex
LuminexWorldwide
100/200Locations
System

Madison
Toronto
s-Hertogenbosch

Tokyo
Austin
Shanghai

Since launching in 1995, Luminex has expanded to include operations in North America, Europe and Asia

40
LuminexImportant
100/200 Numbers
System

Global Headquarters Shipping Address Madison, Wisconsin Japan


12212 Technology Boulevard 12212 Technology Boulevard 1224 Deming Way Kamiyacho Sankei, Building 3F
Austin, TX 78727 Suite 130 Madison, WI 53717 1-7-2 Azabudai
USA Austin, TX 78727 USA Minato-ku, Tokyo 106-0041
US Toll-Free: +1-888-219-8020 USA US Toll-Free +1-877-885-6617 Japan
T +1-512-219-8020 T +1-608-662-9000 T +81-3-5545-7440
F +1-512-219-5195 Order Management F +1-608-662-9185 F +81-3-5545-0451
info@luminexcorp.com Intl Toll-Free +1-866-401-5450 info@luminexcorp.com infojp@luminexcorp.com
T +1-512-336-3550
F +1-512-219-0544 Canada
orders@luminexcorp.com China
439 University Avenue
Unit 6405, Building 6
Toronto, Ontario M5G 1Y8
Technical Support No. 399 Cai Lun Rd.
Canada
US Toll-Free: +1-877-785-2323 Zhangjiang Hi-Tech Park
Intl Toll-Free: +1-800-29-39-49-59 T +1-416-593-4323 Pudong District
T +1-512-381-4397 F +1-416-593-1066 Shanghai 201203
F +1-512-219-5114 info@luminexcorp.com P.R. China
support@luminexcorp.com T +86-21-6165-2665
Europe
F +86-21-6165-0811
Human Resources Het Zuiderkruis 1 chinainfo@luminexcorp.com
F +1-512-401-5496 5215 MV s-Hertogenbosch
opportunities@luminexcorp.com The Netherlands
T +31-73-800-1900
Website Support F +31-73-800-1999
webmaster@luminexcorp.com europe@luminexcorp.com

41
Luminex 100/200 System

42
Luminex 100/200 System

Contact your local Luminex representative


for pricing information.

43
Luminex 100/200 System

www.luminexcorp.com
2014-2016 Luminex Corporation. All rights reserved.
The trademarks mentioned herein are the property of Luminex or their respective owners.

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