Drug Mechanism Dose and Side effects

of Action Microorga Frequency

nism of
Target administra
tion

Primaquine Disrupts the Falciparum 15 mg base

metabolic Plasmodium orally once Fever, dark colored urine, pale
process of a day for 14 or yellowed skin, stomach
plasmodial days cramps
mitochondria;
gametocytic
acitivity
Metronidazole Inhibits Entamoeba 7.5mg/kg Convulsion,blur vision,
synthesis of histolytica orally every discoloration of urine,
nucleic acids 6 hours for
and proteins 7-10 days

Disrupt alterations fever, arthralgia fever, arthralgia and exanthema

Cephalosporin bactericidal in the and
exanthema
s action binding site
of PBP

Penicillin G Target 20S Tanspeptida 1000mg Fever,muscle pain

exerts a se enzyme once daily
bactericidal and for 2 weeks
action protonated

Chloroquine Enters blood Malarial Adult Blur vision,Nerve type

cell, parasite dosage 500 deafness; tinnitus, reduced
inhabiting the mg (= 300 hearing, auditory damage.
parasite cell mg base)
and becomes on exactly
protonated,pr the same
events day of each
biocrystallizat week.
 ion of heme.

Amphotericin Binds to Fungus 0.25 mg to Fever,chills,hypotension

B ergosterol 1 mg/kg per
and forms daily IV for
pores in 1-2 weeks
fungal cell
membrane
Fluconazole Binds to Cryptococcu 400mg per Nausea, dark urine, jaundice,
ergosterol s day orally skin blistering
and form or IV for 8
pores in weeks
fungal cell
membrane

Praziquantel Causes Schistosom Dose Headache,sweating,dizziness,

spams and a worms divided into vomiting etc
paralysis of 2 or 3
muscles doses each
day

Rai Kashan
Student no : 15-2-11631
References
http://www.drugs.com/cipro.html
http://www.drugs.com/drug-class/cephalosporins.html
http://www.everydayhealth.com/drugs/
http://www.drugbank.ca/drugs/DB00431 http://www.drugs.com/cdi/praziquant
el.html