Beruflich Dokumente
Kultur Dokumente
IN IUGR
M ADRIANES BACHNAS
brain structure
reduced total brain volume
altered cortical volume and structure fetal hypoxia
decreased total number of cells
myelination deficits fetal
Brain connectivity is also impaired hyponutrients
neuronal migration deficits
Placental insufficiency
reduced dendritic processes
less efficient networks with decreased long-range
connections. Fetal growth restriction (FGR)
FGR affects 3-9% of pregnancies
neurodevelopmental outcome in high-income countries
Conclusions: Targeted neurosonography provides high-resolution imaging of the fetal brain and is effective in identifying fetuses with
abnormal white matter from a variety of etiological insults. This is primarily accomplished by evaluating abnormalities in transient
laminar patterns in the developing white matter of the fetal cerebrum, with or without intracranial hemorrhage.
I II
PVL
III IV
Korean J
Obstet Gynecol
2012;55(4):257-260
IVH
Malinger G, Kidron D, Schreiber L, Ben-Sira L, Hoffmann C, Lev D, Lerman-Sagie T. Prenatal diagnosis of malformations of cortical
development by dedicated neurosonography. Ultrasound Obstet Gynecol 2007;29(2):17891
The surface of the brain is unusually smooth for a fetus at 28 weeks gestation (the Sylvian fossa is shallow and
there is no sign of the cingulate and precentral gyrus; the texture of the cortex is more irregular and echogenic
than usual.
dr. M Adrianes Bachnas, SpOG (K)FM Fetomaternal FK UNS-RSDM
LONG TERM NEUROLOGICAL
CONSEQUENCES OF IUGR
LOW CRL
PLACENTAL
INSUFFICIENCY SERIAL BIOMETRY
APS antibodies:
B2-GPI, LA, ACA
LOW
DOSE
ASPIRIN Vainio M,
Kujansuu E,
Iso-Mustajarvi M,
Maenpaa J.
L ow
dose
acetylsalicylic
acid
in
Papageorghiou AT,
Yu
CK,
Bindra R,
Pandis G,
Nicolaides KH.
Multicenter
LMWH uterine
artery
notches.
BJOG
2002;109:161-7.
4
g
iv
(slow)
Continued
by
1
g/h
For
24
hour
MgSO4
increases
BDNF
in
fetus