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Study:Kalashpeoplearenotthedescendantsof
AlexandertheGreat
Jun,022015 Author:newsroom
Newresearchhasfoundthattherearestrongerlinkswith
SiberianhuntergatherersthanGreeks
TheKalashpeopletheblondehairedandblueeyedtribeofPakistanclaimtobethe
directdescendantsofAlexandertheGreat,howeverextensivegenetictestinghasshownno Related
connection.
DNAtestingon23KalashpeoplebytheWellcomeTrustSangerInstituteofCambridgetook
samplesfromKalashresidentsofthreedifferentvalleysbutcouldnotconfirmGreek
lineage.
Ancientskeletal
remainsof450
infantsanddogs
foundin
AccordingtotheabstractcompiledbyresearchersfromtheUK,ItalyandPakistan,withQasimAyubatthehelm,
thereisnothingtosupporttheirclaimtobeingGreek:
http://en.protothema.gr/studykalashpeoplearenotthedescendantsofalexanderthegreat/ 1/2
25/9/2016 Study:KalashpeoplearenotthedescendantsofAlexandertheGreat|protothemanews.com
TheKalashrepresentanenigmaticisolatedpopulationofIndoEuropeanspeakerswhohavebeenlivingfor
centuriesintheHinduKushmountainrangesofpresentdayPakistan.PreviousYchromosomeand
mitochondrialDNAmarkersprovidednosupportfortheirclaimedGreekdescentfollowingAlexanderIIIof
Macedonsinvasionofthisregion,andanalysisofautosomallociprovidedevidenceofastronggenetic
bottleneck.Tounderstandtheiroriginsanddemographyfurther,wegenotyped23unrelatedKalashsamples
ontheIlluminaHumanOmni2.5M8BeadChipandsequencedonemaleindividualathighcoverageonan
IlluminaHiSeq2000.ComparisonwithpublisheddatafromancienthuntergatherersandEuropeanfarmers
showedthattheKalashsharegeneticdriftwiththePaleolithicSiberianhuntergatherersandmightrepresent
anextremelydriftedancientnorthernEurasianpopulationthatalsocontributedtoEuropeanandNearEastern
ancestry.SincethesplitfromotherSouthAsianpopulations,theKalashhavemaintainedalowlongterm
effectivepopulationsize(2,3192,603)andexperiencednodetectablegeneflowfromtheirgeographic
neighborsinPakistanorfromotherextantEurasianpopulations.Themeantimeofdivergencebetweenthe
Kalashandotherpopulationscurrentlyresidinginthisregionwasestimatedtobe11,800(95%confidence
interval=10,60012,600)yearsago,andthustheyrepresentpresentdaydescendantsofsomeofthe
earliestmigrantsintotheIndiansubcontinentfromWestAsia.
TheexaminationofDNAshowsthattheKalashcommunityhasmoreincommonwithSiberianhuntergatherersthan
AlexandertheGreat.
http://en.protothema.gr/studykalashpeoplearenotthedescendantsofalexanderthegreat/ 2/2