Maybe its Not a Willpower Thing

The Many OTHER Causes of Overweight - Presented by PointLine Global,

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READER NOTE:
This report is an introduction to the FULL LENGTH ebook

ABOUT THIS REPORT

Maybe Its Not a Willpower Thing

About the information in this report: A balanced body is a healthy body.
Bodies in balance are healthy bodies. Thats natures way.

You are the one person in the world who knows your body best. So, YOU
are the best detective for helping your doctor diagnose your bodys
imbalances. Some are correctable, and some are not, at this time.

The signs and symptoms described in the full length ebook may give you the
information you need to assess if you or a loved one could suffer from one or
more medical syndromes likely originating from imbalances in the body.

Finally, overcome your willpower hurdle. Maybe its not a willpower thing!

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The full length ebook is available exclusively here:
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Maybe Its Not a Willpower Thing
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We Introduce:
Mr. DANIEL LAMBERT, of Leicester, England The Greatest Curiosity in the World!
At the age of 36, he weighed upwards of fifty stone (700 lb; 318 kg), and was the heaviest
authenticated person up to that point in recorded history.

During this period of English history no real stigma was attached to obesity, and Lambert was
generally considered a wonder to be marveled at, rather than to be sneered. (More at the end of
this report)

Overweight & Obesity At-A-Glance

Obesity: A status with body weight that is much above the acceptable or desirable weight,
usually due to accumulation of excess fat in the body. The standards may vary with age, sex,
genetic or cultural background.

Obesity in pets is common in many countries. In the United States, 2341% of dogs are
overweight, and about 5% are obese. The rate of obesity in cats was slightly higher at 6%

In the Body Mass Index, a measurement obtained by dividing a person's weight by the square
of the person's height, a BMI greater than 30.0 kg/m2 is considered obese. A BMI greater than
40.0 kg/m2 is considered morbidly obese. (More in full ebook pages 8, 22-28)

Genetic syndromes
Studies have identified variants in several genes that may contribute to weight gain and body fat
distribution; although, only in a few cases are genes the primary cause of obesity.

Obesity is a major feature in several syndromes, such as:

Prader-Willi syndrome
Bardet-Biedl syndrome
Cohen syndrome
MORM syndrome
MOMO syndrome

The genetics of common obesity is complex, and an important thread through this labyrinth is the
study of genetic syndromes in which obesity is a major component.

The percentage of obesity that can be attributed to genetics varies widely, depending on the
population examined, from 6% to 85%.

As of 2006, more than 41 sites on the human genome have been linked to the development of
obesity when a favorable environment is present.

The involvement of genetic factors in the development of obesity is estimated to be 4070%.

(More in full ebook pages 64-85)

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Body Mass Index (BMI)
The body mass index (BMI) is a value derived from the mass (weight) and height of an
individual. The BMI is defined as the body mass divided by the square of the body height, and is
universally expressed in units of kg/m2, resulting from mass in kilograms and height in metres.

The BMI is an attempt to quantify the amount of tissue mass (muscle, fat, and bone) in an
individual, and then categorize that person as underweight, normal weight, overweight,
or obese based on that value. However, there is some debate about where on the BMI scale the
dividing lines between categories should be placed. Commonly accepted BMI ranges are
underweight: under 18.5, normal weight: 18.5 to 25, overweight: 25 to 30, obese: over 30.

PraderWilli syndrome
PraderWilli syndrome is frequently associated with an extreme and insatiable appetite, often
resulting in morbid obesity. It is the most common genetic cause of morbid obesity in children.

Characteristic of PWS is a chronic feeling of hunger that can lead to excessive eating and life-
threatening obesity. The incidence of PWS is between 1 in 25,000 and 1 in 10,000 live births.

BardetBiedl syndrome
The BardetBiedl syndrome (BBS) is a ciliopathic human genetic disorder that produces many
effects and affects many body systems.

As of 2012, 14 or 15 different BBS genes had been identified. Recent findings in genetic research
have suggested that a large number of genetic disorders were not previously identified in the
medical literature.

BBS is one such syndrome that has now been identified to be caused by defects in the cellular
ciliary structure.

Historically, mental retardation has been considered a principal symptom but is now not regarded
as such. Obesity is possibly related to a decreased sensory function that would normally indicate
satiation the feeling of fullness which triggers us to stop eating.

Most cases of Bardet-Biedl syndrome are inherited as an autosomal recessive trait. Genetic
diseases are determined by the combination of genes for a particular trait that are on the
chromosomes received from the father and the mother.

Cohen syndrome
Cohen syndrome is also known as Pepper syndrome or Cervenka syndrome. More than 80% of
individuals with this syndrome are reported to be underweight during early childhood, but
overweight afterward. The obesity tends to be truncal in nature.

Cohen syndrome is diagnosed by clinical examination, but often difficult due to variation in
expression. Early diagnosis of Cohen Syndrome can make a positive impact as this enables
medical and therapeutic interventions to ensure children thrive. Intensive therapies such as O.T.,
P.T. and Speech are critical to ensure maximum development of gross/fine motor functions.

Cohen Syndrome children are known to have a very friendly disposition and a positive outlook.

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MORM syndrome
MORM syndrome is an autosomal recessive congenital disorder.

This means that the disorder is present from birth and is likely the result of both healthy parents
passing on a defective gene, associated with MORM syndrome, to their offspring. The disorder is
not dependent on sex of the child, as both males and females are equally likely to inherit the
disorder.

MORM syndrome is associated with the gene INPP5E. Although not well understood, it is
hypothesized to play a role in primary cilia stability. This phenotype shows similarities to two
autosomal recessive disorders, BardetBiedl syndrome and Cohen syndrome.

Truncal obesity is a term used to describe the buildup of fat around ones trunk or torso as opposed
to the extremities.

MOMO Syndrome
MOMO syndrome is an extremely rare genetic disorder which belongs to the overgrowth
syndromes and has been diagnosed in only six cases around the world, and occurs in 1 in 100
million births. It is unknown if it is a life-limiting condition.

Genetic testing is not available for MOMO syndrome as the underlying cause of MOMO
syndrome has yet to be determined. Diagnosis is based upon clinical findings (i.e., symptoms).

Current research suggests that it is linked to a de novo (new) autosomal dominant mutation. If a
disease is autosomal dominant, it means that you only need to get the abnormal gene from one
parent in order for you to inherit the disease.

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Autosomal dominance is a pattern of inheritance characteristic of many genetic diseases.
"Autosomal" means that the gene in question is located on one of the numbered, or non-sex,
chromosomes. "Dominant" means that a single copy of the disease-associated mutation is enough
to cause the disease. This is in contrast to a recessive disorder, where two copies of the mutation
are needed to cause the disease. MOMO syndrome is one example of an autosomal dominant
genetic disorder. (Definition from: Talking Glossary of Genetic Terms from the National Human
Genome Research Institute.)

There have been few cases of MOMO syndrome reported in the medical literature, and information
about long-term complications associated with the disease is scarce. Furthermore, potential
complications likely depend on the specific signs and symptoms present in each affected
individual.

Leptin Deficiency
The discovery of leptin39 and the leptin receptor40 heralded a new era in obesity research.

It has been suggested that the main role of leptin is to act as a starvation signal when levels
are low, to help maintain fat stores for survival during times of starvation.

Leptin, the "satiety hormone", is made by adipose (fat) cells. They help to regulate energy
balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger
hormone". Together, these two hormones keep the hunger desire in balance.

In obesity, a decreased sensitivity to leptin occurs, resulting in an inability to detect satiety despite
high energy stores.

Leptin deficiency from disruption of both leptin genes results in severe obesity in mice and
humans. Numerous studies of laboratory rodents provide strong evidence that genetics plays an
important role in obesity. (More in full ebook pages 75-88)

Cushings syndrome
Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissues to high
levels of the hormone cortisol.

Sometimes called hypercortisolism, Cushing's syndrome is relatively rare and most commonly affects
adults aged 20 to 50.

Cushing's syndrome in children is rare. An estimated 10 to 15 of every million people are affected a
year and only about ten percent of these new cases occur in children.

Deposits of fat in the cheeks give a moon face appearance. Breakdown of protein in the connective
tissues of the skin makes the skin thin, allowing blood vessels to show through and give the cheeks a
reddened appearance.

The abdomen is obese, while the extremities are thin and there is muscle wasting and weakness. Dark
facial hair and amenorrhea (an abnormal absence of menstruation) occur only with Cushings disease.
(More in full ebook pages 37-43)

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Depressive Disorders
A depressive disorder is an illness that involves the body, mood, and thoughts. It affects
the way a person eats and sleeps, the way one feels about oneself, and the way one
thinks about things.

A depressive disorder is not the same as a passing blue mood. It is not a sign of
personal weakness or a condition that can be willed or wished away.

Many depressed individuals seek solace in overeating. Chronic overeating often

becomes an unhealthy lifestyle. Specialists have identified a variety of diseases associated
with obesity and immunological complications.

Major depression is manifested by a combination of symptoms that interfere with the ability to
work, study, sleep, eat, and enjoy once pleasurable activities. Such a disabling episode of
depression may occur only once but more commonly occurs several times in a lifetime.

A less severe type of depression, dysthymia, involves long-term, chronic symptoms that do
not disable, but keep one from functioning well or from feeling good. Many people with
dysthymia also experience major depressive episodes at some time in their lives.

Another type of depression is bipolar disorder, also called manic-depressive illness. Not
nearly as prevalent as other forms of depressive disorders, bipolar disorder is characterized by
cycling mood changes: severe highs (mania) and lows (depression).

Many women are also particularly vulnerable after the birth of a baby. The hormonal and
physical changes, as well as the added responsibility of a new life, can be factors that lead to
postpartum depression in some women. (More in full ebook pages 44-55)

Authors note: Transcranial Magnetic Stimulation (TMS) is a new therapy that involves no
drugs and is proven safe and effective for treatment-resistant depression! TMS is free of the
negative side effects often associated with taking antidepressants. More Info

Menopause
Changing levels of estrogen and progesterone can cause a variety of symptoms. Visible changes
with menopause may include a thickening at the waist, loss of muscle mass and increase in fat
tissue, or thinning and loss of stretchiness in the skin. (More in full ebook pages 56-60)

Binge Eating Disorder

Binge eating means eating a large amount of food in a short period of time. Most of us may
overeat during a special occasion, like a holiday. But people who have this emotional disorder
binge eat on a regular basis and feel a lack of control over their eating.

People with binge eating disorder are usually very upset by their binge eating and may
experience stress, trouble sleeping, and depression. Binge eating disorder may lead to weight gain
and to related health problems, such as heart disease and diabetes.

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Binge eating disorder is the most common eating disorder in the United States. Among adults,
about 3.5 percent of women and 2 percent of men are estimated to have binge eating disorder.
About 1.6 percent of adolescents may also be affected. (More in full ebook pages 61-63)

Rare Disease Resources

Medical Resources
Many individuals want to know about healthcare professionals or researchers who have knowledge
of their conditions. When a condition is rare, it can be difficult to find someone who has seen many
cases. Although there is no list of experts in rare diseases,

GARD's How to Find a Disease Specialist fact sheet provides several ways to identify healthcare
professionals who have experience with a particular condition. Click on the link to access this
resource and learn more.

Genetics Resources
Individuals who have concerns about a genetic syndrome may wish to contact a genetics
professional. The following online resources can help you find a genetics professional in your
community:
The National Society of Genetic Counselors provides a searchable directory of US and
international genetic counseling services.
The American College of Medical Genetics has a searchable database of US genetics
clinics.
The University of Kansas Medical Center provides a list of US and international genetic
centers, clinics, and departments.
The American Society of Human Genetics maintains a database of its members, which
includes individuals who live outside of the United States. Visit the link to obtain a list of the
geneticists in your country, some of whom may be researchers that do not provide medical
care.

Parent and Caregiver Resources

The Parent Technical Assistance Center Network provides a list of the Parent Training and
Information Centers in each state. These centers are funded by the United States Department of
Education to provide early intervention and special education information and training to parents of
children with disabilities from birth to age 26. Click on the link to find the Parent Center in your
state.

A Free Tool to Help Diagnose Rare Diseases

The FDRF offers a beta version of their free online diagnosis assistant. Their tool is different from
other online systems that help diagnose rare diseases, in that they've designed it to mimic an
expert clinician. The tool asks questions about different signs and symptoms of diseases and uses
a proprietary method for matching symptoms with a disease.

Each disease in the database has been characterized by hand, which allows them to provide
carefully curated data for the tool to use. You may access the tool here.

(More Resources in full ebook pages 117-135)

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Cause of Daniel Lamberts Extreme Weight
It is impossible to be certain about what caused Daniel Lambert's extreme weight, but it is
considered unlikely to have been caused by an endocrine (glandular) or genetic disorder. Other
than his weight gain, he showed no symptoms of a thyroid disorder, and none of his many portraits
show the moon face of a patient with Cushing's syndrome.

Patients with BardetBiedl syndrome and PraderWilli syndrome suffer from learning
disabilities and muscular weakness. But all those who knew Lambert agreed that he was highly
intelligent, was extremely strong physically, and did not suffer from any health problems.

Although he had an aunt and uncle who were overweight, his parents and surviving siblings
remained of normal build throughout their lives.

Consequently, it is likely that Lambert's weight gain was caused not by a physical disorder but by a
combination of overeating and a lack of exercise. Although heavily built in his teens, he began to
gain weight only when he took up the relatively sedentary job of prison keeper.

Cause of Lamberts Death in 1809

In June 1809, he died suddenly in Stamford. His coffin required 112 square feet (10.4 m2) of wood
and was built with wheels to allow easy transport. It still took 20 men almost half an hour to drag
his casket into the trench in a newly opened burial ground.

Lambert's position as the heaviest person in recorded history was soon overtaken by the
American Mills Darden (17991857), but Lambert had by now become a cult figure, and virtually
every item connected with him was preserved for posterity.

Presented by PointLine Global, maker of AccuPoint brand bathroom

scales most accurate

Maybe its Not a Willpower Thing!

The many (other) causes of overweight

Compliments of:

PointLine Precision
Bringing you ACCUPOINT
The most accurate digital bathroom scale
Available on Amazon.com

Search Amazon.com for Item # B01623P59Y

www.PointLineGlobal.com 2016 PointLine Precision AccuPoint Scale