Beruflich Dokumente
Kultur Dokumente
FORMULARY
OF MEDICATIONS IN USE
and
LABORATORY
MANUAL
ROOD & RIDDLE EQUINE HOSPITAL
P.O. BOX 12070
LEXINGTON, KY 40580
859-233-0371
www.roodandriddle.com
859-246-0112
Fax 859-246-1760
www.roodandriddlevetpharm.com
859-233-0371
email: lab@roodandriddle.com
ROOD & RIDDLE EQUINE HOSPITAL 2007
DISCLAIMER
ROOD & RIDDLE EQUINE HOSPITAL MAKES NO REPRESENTATIONS OR WARRANTIES, AND DISCLAIMS
ALL WARRANTIES, EXPRESS OR IMPLIED, CONCERNING THE CONTENTS OR USE OF THE FORMULARY AND
LABORATORY MANUAL. WITHOUT LIMITING THE GENERALITY OF THE FOREGOING, ROOD & RIDDLE
EQUINE HOSPITAL HEREBY DISCLAIMS ANY IMPLIED WARRANTIES WITH RESPECT TO THE FORMULARY AND
LABORATORY MANUAL, INCLUDING WITHOUT LIMITATION ANY IMPLIED WARRANTIES OF MERCHANTABIL-
ITY, FITNESS FOR A PURPOSE, AESTHETICS, OR NON-INFRINGEMENT.
FURTHER, ROOD & RIDDLE EQUINE HOSPITAL MAKES NO WARRANTY CONCERNING THE ACCURA-
CY OF THE INFORMATION CONTAINED IN THE FORMULARY AND LABORATORY MANUAL. THE USE OF
INFORMATION FROM THE FORMULARY AND LABORATORY MANUAL IS THE SOLE RESPONSIBILITY OF THE
PRACTITIONER DIRECTING THE CARE OF THE PATIENT.
IN NO EVENT SHALL ROOD & RIDDLE EQUINE HOSPITAL HAVE LIABILITY OF ANY KIND INCLUDING
ANY SPECIAL, INDIRECT, INCIDENTAL, CONSEQUENTIAL, EXEMPLARY OR PUNITIVE LOSSES OR DAMAGES,
EVEN IF ROOD & RIDDLE EQUINE HOSPITAL KNEW OR SHOULD HAVE KNOWN OF THE POSSIBILITY OF SUCH
POTENTIAL LOSSES OR DAMAGES RESULTING FROM INFORMATION CONTAINED IN OR USE OF THE FORMU-
LARY AND LABORATORY MANUAL.
ROOD & RIDDLE EQUINE HOSPITAL
FORMULARY OF MEDICATIONS IN USE
The Rood and Riddle Equine Hospital Formulary of Medications in Use contains medications and
dosages in use in our practice. This guide is intended as an aide to practitioners, but should not be viewed
as a recommendation for the use of any medication, nor should it be viewed as a complete or comprehensive
listing of all uses, indications, or adverse effects. Please note that the use of many medications is extra-label
or off-label. Drugs are listed by generic names, followed by the trade name in some cases.
TABLE OF CONTENTS
FORMULARY page 1
General Formulary page 1
Ophthalmology page 7
Anesthesia page 11
Theriogenology page 13
13
14
MEDICATION DOSAGE INDICATIONS
Prostaglandin F2 [Lutalyse] 7.5 - 10mg IM Lysis of CL.
(5mg/ml)
Sulpiride 400mg IM SID for 10-16d Enhance follicular development.
INTRA-UTERINE TREATMENTS:
DMSO (90%) 50ml DMSO /L (900mg/ml = 4.5% solution) Decrease mucus.
followed by 1 liter saline or LRS only
Titratable iodine 1.0% 15cc Povidone Solution/L (1.5% solution) Disinfectant.
[Povidone Solution] followed by 1 liter saline or LRS only
Vinegar (white vinegar) 100 ml vinegar/L Saline; Lavage until fluid clears Yeast infections.
Mannose Add 500ml sterile water to 25 g; Infuse 100 ml Streptococcus or E. coli endometritis.
into uterus, wait 30 minutes, then lavage with
saline/LRS
Add 333ml sterile water to 25 g (75mg/ml) solution); Pseudomonas endometritis.
Infuse 100ml into uterus, wait 30 minutes, then
lavage with saline/LRS
INTRA-UTERINE ANTIBIOTICS
(qs to 60 ml with saline or
sterile water)
Amikacin (250mg/ml) 2g, Buffer with 35ml of 8.4% Bicarb
Ampicillin (250mg/ml) 2g
Ceftiofur (Naxcel) 1-2 g
Gentamicin (100mg/ml) 2g, Buffer with 35ml of 8.4% Bicarb
Polymyxin B (500,000 U/vial) 1,000,000 units
Potassium Penicillin 10 million units
Ticarcillin and clavulanate [Timentin] 3.1-6.2g
VETERINARY LABORATORY MANUAL
859-233-0371
Fax 859-280-3489
lab@roodandriddle.com
PHYSICAL ADDRESS:
2150 Georgetown Road Lexington, KY 40511
LEGEND
RED Top No additive
PURPLE Top EDTA
GREEN Top Heparin
BLUE Top Sodium citrate
YELLOW Top ACD
15
16
VETERINARY LABORATORY AVAILABLE TESTS
TEST SAMPLE REQUIRED COMMENTS
Hematology - same day results
Complete CBC Purple and Red top Includes differential and fibrinogen
CBC Pre-surgery Purple and Red top Includes a fibrinogen
CBC Purple top No differential or fibrinogen
Fluid Analysis Purple top Includes WBC, RBC, TP
CSF Analysis Purple and Red top Includes WBC, RBC, MTP
17
18
TEST SAMPLE REQUIRED COMMENTS
Serology
AGID Coggins 24 hours* Red top Set up at 3PM and available the following day at 3PM
ELISA Coggins 2 hours* Red top Upon submission, notify lab technician
*Online EIA results are also available via GlobalVetLink
Microbiology
*****Results are not finalized until 72 hours after submission
*****All samples with positive preliminary results are called to the doctor each morning
Culture / Sensitivity Amies media, sterile container, or swab Label the sample with patient, Dr, site
Salmonella Specimen in sterile container or swab 48 hours before preliminary results
ARD Culture Fluid sample in sterile container Antibiotic Removal Device
Anaerobic Amies media, sterile container, or swab
Mycology/Fungal Amies media, sterile container, or swab Results may take 3-21 days
ADULT VALUES
UNITS RREH LAB THOROUGHBRED STANDARDBRED MINIATURE HORSE DRAFT
HgB g/dl 11-14 10.9-18.8 11.3-17.9 9-16 8-14
PCV % 30-42 29-53 31-48 23.7-42.7 24-42
RBC 106/ ul 8-10 6.5-11.6 6.9-10.7 4.27-10.3 5.5-9.5
MCV fl 39-49 40-49 38-60.5
MCHC g/dl 337-386 350-410 327-397
WBC 103/ ul 7,000-12,000 5,300-11,000 6,900-10,700 6,100-12,490 6,000-12,000
SEG 103/ ul 3500-8400 (50-70 %) 1855-7480(35-68%) 2277-6741(33-63%) 1638-6745 (22-54%) 2100-9000 (35-75%)
STAB 103/ ul 0-240 (0-2%) 0-220 (0-2%) 0-535 (0-5%) 0-375 (0-3%) 0-240 (0-2%)
LYMPH 103/ ul 1400-4800 (20-40%) 1378-6270 (26-57%) 1932-5992 (28-56%) 3149-9617 (41-77%) 120-1200 (2-10%)
MONO 103/ ul 0-360 (0-3%) 0-660 (0-6%) 0-535 (0-5%) 0-500 (0/4%) 120-1440 (2-12%)
EOS 103/ ul 0-120 (0-1%) 0-800 (0-7%) 0-700 (0-6%) 0-874 (0-7%) 0-360 (0-3%)
Bands 103/ ul rare 0-110 (0-1%) 0-214 (0-2%) 0-460 (0-4%) 0-222 (0-2%)
TP g/dl 5.8-7.6 6.0-7.5 5.4-7.5 5.2-7.9 6.4-8.
BUN mg/dl 8-26. 11-24 8-14 15.2-32.5 11.3-17.7
CREAT mg/dl .08-2 .9-2.1 .9-1.7 0.7-1.4 1.4-2.0
SGOT(AST) U/l 80-240 141-330 123-789 140-306 71.5-396.9
FIB mg/dl 200-400 150-380
T. BILI mg/dl .8-2 .9-2.6 .9-2.9 .7-1.7
IND. BILI mg/dl .3-1.7 .6-2.5
D. BILI mg/dl .2-1 .2-.8 .2-.7
SAP U/l 50-150 26-92 24-67 81-304 55.7-127.1
LDH U/l 52-240 81-225 74-206
CPK (CK) U/l 50-250
SDH U/l 0.8-4.2
GGT U/l 6-24. 6-29
ALBUMIN g/dl 2.4-5 2.9-3.6 2.7-3.4 3.1-4.1
Ca mg/dl 9-12.5 10.7-12.4 10.9-12.9 10.16-12.56 10.8-13
P mg/dl 3-6. 1.1-4.4 2.2-4.2 2.81-6.75 2.8-4.2
GLU mg/dl 60-110 69-150 63-101 68-126 56.7-95.1
Na mmol/l 136-144 134-142 137-143 132-140 131.9-142.3
K mmol 3.6-5 2.1-4.2 29.-4.4 3.66-5.32 3.1-4.1
Cl mmol/l 92-102 94-106 96-102 97.3-106.5
HCO3 mmol/l 21-28 21.4-27.2
Mg mEq/l 1.8-2.3 .53-.84
Lumsden, Rowe, Mullen 1980 Harvey, et al 1984 Gelser, et al 1984
19
20
FOAL VALUES
UNITS F<12HR F-1DY F-1WK F-1MO F-3MO F-6MO F-12MO
HgB g/dl 12.6-17.4 12-16.6 10.7-15.8 10.9-15.3 11.7-15.3 10.8-15.4 11-15.4
PCV % 37-49 32-46 28-43 29-41 32-42 29-41 31-42
RBC x106/ ul 9-12 8.2-11 7.4-10.6 7.9-11.1 9.2-12 7.9-11.6 7.7-10.9
MCV fl 36-45 36-46 35-44 33-40 31-38 32-39 35-44
MCHC g/L 320-400 320-400 350-400 340-400 340-400 330-400 340-400
WBC x103/ ul 6.9-14.4 4.9-11.7 6.3-13.6 5.3-12.2 6.7-16.8 7.8-11.6 6.5-11.8
SEG x103/ ul 5.55-12.38 3.36-9.57 4.35-10.55 2.76-9.27 3.92-10.35 2.89-5.56 2.66-5.9
LYMPH x10 / ul
3
.46-2.54 .67-2.12 1.43-2.28 1.73-4.85 2.88-7.15 3.2-6.01 2.01-6.53
MONO x103/ ul .04-.43 .07-.39 .03-.54 .05-.63 .12-.76 .04-.45 .04-.44
EOS x10 / ul
3
0 0.-.02 0-.09 0-.12 0-.55 0-.55 0-.78
BASO x10 / ul
3
0-.02 0-.03 0-.18 0-.08 0-.07 0-.06 0-.09
TP(plasma) g/dl 5.1-7.6 5.2-8. 5.2-7.5 5.1-7.1 5.5-7.1 5.9-7.1 5.4-7
BUN mg/dl 12.-27 9-40 4-20 6-21 7-20 15-30 15-24
CREAT mg/dl 1.7-4.2 1.2-4.3 1-1.7 1.1-1.8 .7-2.2 1.2-2.1 1.3-2.1
SGOT(AST) U/l 97-315 146-340 237-620 252-440 282-480 300-620 283-720
FIB mg/dl 100-350 100-400 150-450 200-550 100-550 200-550 200-550
T. BILI mg/dl .9-2.8 1.3-4.5 .8-3 .5-1.7 .4-2 .3-1.3 .4-1.4
IND. BILI mg/dl .8-2.5 1.-3.8 .5-2.3 .4-1.2 .4-1.4 .1-.6 .2-.6
D. BILI mg/dl .3-.6 .3-.7 .3-.7 .1-.6 .1-.7 .1-.7 .1-1
SAP U/l 152-2835 861-2671 137-1169 210-866 206-458 155-226
CPK (CK) U/l 65-380 40-909 52-143 81-585 57-204 97-396
SDH U/l .2-4.8 .6-4.6 .8-8.2 1.2-5.9 1.1-3.9 .3-3.3
GGT U/l 13-39 18-43 14-164 17-99 0-27 0-26
ALBUMIN g/dl 2.7-3.9 2.5-3.6 2.7-3.4 2.7-3.4 2.8-3.5 3.-3.5 3.1-3.8
Ca mg/dl 10.8-14.8 9.7-13.7 11.3-13.7 11-13.4 11.2-13.2 10.2-13.4 11.3-14.1
P mg/dl 3.1-6.3 3.8-7.4 5.4-9.4 4.9-9.3 6.3-8.3 4.8-7.6 5.2-6.8
GLU mg/dl 108-190 121-233 121-192 130-216 88-179 110-210 105-165
Na mmol/l 133-163 123-159 130-154 136-154 140-156 133-153 134-158
K mmol 3.4-5.4 3.6-5.6 3.8-5.8 3.8-5.4 3.4-5.8 2.8-5.6 2.2-5.4
Cl mmol/l 93-117 93-117 94-110 97-109 102-110 98-112 99-109
CO2 mEq/l 20-30 24-32 22-32 23-31 22-30 27-31
Mg2+ mg/dl .7-2.3 .6-4.2 1.4-2.6 1-3 1.6-2.8 1.7-3.1
Harvey et al (1984) and Bauer et al (1984)
MISCELLANEOUS DIAGNOSTIC TESTS
TEST NORMAL VALUES
Clotting Tests
Prothrombin time 8-13 seconds
PTT 30-60 seconds
Platelet count 100,000-350,000 (Jain, 1986)
***from RREH lab and Jain (1986)
Urinalysis
Color pale yellow to brown
Viscosity viscous (mucoid)
Transparency slightly turbid
Specific gravity 1.008-1.042 (foal 1.001-1.027)
Dipstick Chemistries
pH 7.0-9.0 (acidic urine is normal in foals)
protein none to possible trace
glucose none
ketones none
bilirubin none
blood none
21
22
TEST NORMAL VALUES
T3 0.5-6.0 ng/ml
T4 9.0-36.0 ng/ml
http://www.globalrph.com/conv_si.htm
23
24
REFERENCES FOR NORMAL LABORATORY VALUES
Aguilera-Tejero E, Estepa JC, Lopez I, et al. Arterial blood gases and acid-base balance in healthy young and aged horses. Equine Vet
Journal 1998; 30(4):352-354.
Bauer JE, Asquith RL, Kivipelto J. Serum biochemical indicators of liver function in neonatal foals. Am J Vet Res 1989; 50(12): 2037-
2041.
Bauer JE, Harvey JW, Asquith RL, et al. Clinical chemistry reference values of foals during the first year of life. Equine Vet. Journal
1984; 16(4): 361-363.
Brewer BD, Clement SF, et al. Renal Clearance, Urinary Excretion of Endogenous Substances, and Urinary Diagnostic Indices in
Healthy Neonatal Foals. Journal of Veterinary Internal Medicine 1991; 5 (1): 28-33.
Gelser DR, Goble DO, Held JP. Normal Hematology and Serology of the Clydesdale Draft Horse. Equine Practice 1984; 6(10): 7-11.
Harvey JW, Asquith RL, McNulty PK, et al. Haematology of foals up to one year old. Equine Vet Journal 1984; 16(4): 347-353.
Harvey RB, Hambright MB, Rowe LD. Clinical biochemical and hematologic values of the American Miniature Horse: Reference
values. Am J Vet Res 1984;(5): 987-990.
Jain NC. The horse: normal hematology with comments on response to disease. In Schalms Veterinary Hematology, 4th edition,
1986, Philadelphia, Lea & Febiger.
Kohn CW, Chew DJ. Laboratory diagnosis and characterization of renal diseases in horses. Vet Clinics North America Equine Pract.
1987; 3:585-615.
Kohn CW, Strasser SL. 24-hour renal clearance and excretion of endogenous substances in the mare. Am J Vet Res. 1986;
47(6):1332-1337.
Lumsden JH, Rowe R, Mullen K. Hematology and Biochemistry Reference Values for the Light Horse. Can. J. Med 1980; 44(1): 32-42.
Nelson AW. Analysis of equine peritoneal fluid. Vet Clinics North America Large Animal Practice 1979; 1:267-274.
Ralston SL, Baile CA. Plasma glucose and insulin concentrations and feeding behavior in ponies. J Animal Sci 1982; 54(6): 1132-
1137.
Soma LR, Uboh CE, Nann L, et al. Prerace venous blood acid-base values in Standardbred horses. Equine Vet Journal 1996;
28(5):390-396.
Tew WP Synovial fluid analysis: applications in equine joint injury and disease. Proceedings of the 28th Annual Meeting of the
American Association of Equine Practitioners. 1983; 121-122.
LABORATORY TESTS SENT TO REFERRAL LABORATORIES
Some laboratory tests are not performed at Rood & Riddle Veterinary Laboratory and should be sent directly to referral laboratories.
A list of these tests and the name of the laboratory that performs each test for Rood & Riddle Equine Hospital is listed following the test.
These tests and the names of laboratories are included to aid practitioners; please note that there are likely other laboratories performing
these tests, and in some cases, you may be required to send specimens to a laboratory in your state.
Please call the laboratory before sending a specimen to:
1. Confirm the type of sample needed;
2. Give shipping instructions;
3. Set up an account for billing.
27
28
LEGEND
AUBURN - Auburn University, Department of Pathobiology, Clinical Pathology Laboratory, 166 Greene Hall, Auburn University, AL 36849 (334) 844-2653
BET- BET, Inc. - 1501 Bull Lea Road, Suite 102, Lexington, KY 40511 (859) 273-3036
CORNELL - Cornell University, Animal Health Diagnostic Center, Upper Tower Road, Ithaca, NY 14853 (607) 253-3900
GLUCK - Gluck Equine Research Center, 1400 Nicholasville Road, Lexington, KY 40546 (859) 257-4757
IDEXX - Equine Biodiagnostics, 1501 Bull Lea Road, Suite 104, Lexington, KY 40511 (800) 621-8378
HPA - HPA Laboratories Inc., 10338 Stony Run Lane, Ashland, VA 23005 (800) 730-0095
KSU - Kansas State Veterinary Diagnostic Laboratory, 1800 Denison Avenue A-117, Manhattan, KS 66506 (785) 532-5650
LIMESTONE - Limestone Veterinary Laboratory, 1033 N. Limestone Street, Lexington, KY 40505 (859) 252-0415
MSU - Michigan State University, Diagnostic Center, 4125 Beaumont Road, Lansing, MI 48910 (517) 353-1683
MURRAY - Breathitt Veterinary Center, Murray State University, 715 North Drive, P.O. Box 2000, Hopkinsville, KY 42241 (270) 886-3959
NVSL - National Vet Services Laboratories, 1800 Dayton Avenue, Ames, IA 50010 (515) 663-7563
NEW BOLTON CENTER - University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348 (610) 444-5800
OSU - The Ohio State University, College Of Veterinary Medicine, 1925 Coffey Road, Columbus, OH 43210 (614) 688-4687
PENN - University of Pennsylvania, Clinical Pathology Laboratory, 3950 Delancey Street, Philadelphia, PA 19104 (215) 898-7874
UC DAVIS - UC Davis-VMTH, Building VMTH Room 1017, 1 Garrod Drive, Davis, CA 95616 (530) 752-7380
UKLDDC - University of Kentucky Disease Diagnostic Laboratory, 1429 Newtown Pike, Lexington, KY 40511 (859) 253-0571
UMINN - University of Minnesota, Veterinary Diagnostic Laboratory, 1333 Gortner Avenue, St. Paul, MN 55108 (612) 625-8787
VetGen - Veterinary Genetics Lab, UC Davis, One Shields Ave., Davis, CA 95616-8744 (530) 752-9780