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Bordetella Pertussis

Yesenia Segarra, Class, 9/14/15


Assignment
Open the link below to view the assignment. Before your presentation, you may delete
this slide OR move it to the last slide. If you would like to trade bacteria with someone
in the class, please notify me of this change.

Whos Who in the World of Bacteria


What is Bordetella Pertussis?
Bordetella Pertussis is a small coccobacillus, which is a rod shaped bacteria.
Whooping cough (pertussis) is caused by the bacterium bordetella pertussis.
Its natural habitat is the human respiratory system.
Whooping cough, or pertussis, is a respiratory infection in which a whooping
sound is produced when the patient breathes.
Pertussis kills an estimated 300,000 children annually, most of which occur in
developing countries.
When was it discovered & by who?
Jules Bordet and Octave Gengou discovered bordetella Pertussis,
first as whooping cough.
They identified a small ovoid Gram-negative bacterium in an
expectorate fluid specimen obtained from a 5-month-old child.
Jules Bordet can be considered as the father of the Belgian
Microbiology school.
Other physical characteristics
Has been shown recently to enter and survive in epithelial cells and macrophages
in vitro.
Cell cytotoxicity mediated by bordetella pertussis occurred through apoptosis, as
shown by changes in nuclear morphology and by host cell DNA fragmentation.
There is..
Bordetella Bronchiseptica
Bordetella Parapertussis
Beneficial or Harmful?
Known as a childhood illness, whooping cough is actually most common in
adolescents and adults. They pass whooping cough to other family members
without realizing that their cold-like symptoms are really pertussis.
This disease is very harmful to humans, especially young infants and children.
Nine in 10 babies are hospitalized
15% to 20% develop pneumonia
2% to 4% have seizures
One in 100 will die from complications of pertussis
Where is it typically found?
This is typically found in children and young infants.
Between 2000 and 2006 there were 156 deaths from pertussis, more than
90% of those were in children less than 1 year old, and, fully 120 of the 156
deaths (77%) were newborns less than 1 month old.
Sometimes babies don't cough or whoop as older kids do. Infants may
look as if they're gasping for air with a reddened face and may actually
stop breathing (this is called apnea) for a few seconds during very bad
spells.
Continued
Bordetella is also common with dogs. It is mostly
known as kennel cough and most puppies at a young
age, require a vaccine to prevent it.
What type of conditions are needed to survive?
Pertussis is treatable. The antibiotics erythromycin, azithromycin,clarithromycin,
and trimethoprim/sulfamethoxazole are all effective against the Bordetella
bacteria. However, by the time the cough becomes severe and pertussis typically
diagnosed, antibiotic therapy may be too late to relieve the symptoms.
Treatment may not ease symptoms, but it can reduce the chance of spreading
pertussis. When one person in a household is known to have whooping cough,
experts recommend everyone in the home receive antibiotic treatment as well.
Daycare and school contacts may also need to be treated preventively.
Work Cited
"Explore." Pertussis. N.p., n.d. Web. 14 Sept. 2015.
<http://www.museumofhealthcare.ca/explore/exhibits/vaccinations/pertussis.html>.
"Bordetella Pertussis." Bordetella Pertussis. N.p., n.d. Web. 14 Sept. 2015.
<http://bioweb.uwlax.edu/bio203/s2007/wolf_bri2/>.
<https://microbewiki.kenyon.edu/index.php/Bordetella_pertussis>.
N.p., n.d. Web. <http://cid.oxfordjournals.org/content/49/10/1565.full>.