Sie sind auf Seite 1von 8

Curr Psychiatry Rep (2016) 18:41

DOI 10.1007/s11920-016-0670-9

COMPLEX MEDICAL-PSYCHIATRIC ISSUES (MB RIBA, SECTION EDITOR)

Child Psychiatric Emergencies: Updates on Trends, Clinical Care,


and Practice Challenges
Beau Carubia 1,3 & Amy Becker 1,2 & B. Harrison Levine 3

# Springer Science+Business Media New York 2016

Abstract Over the past 15 years, the number of pediatric Introduction


patients presenting to the emergency room in psychiatric crisis
has nearly doubled. Suicidality and aggression are among the It is estimated that 1020 % of children and adolescents suffer
most common presenting problems, making it important for from a mental disorder or substance use problem, which trans-
providers to have up-to-date knowledge about the assessment lates into nearly eight million youth in need of care [14]. The
and management of these frequently encountered clinical is- Patient Protection and Affordable Care Act (ACA) signed into
sues. Psychometrically sound suicide risk assessment tools are law in 2010 allowed states to expand Medicaid eligibility and
available for use in the emergency room setting, which can be simplify enrollment in the State Childrens Health Insurance
administered efficiently with minimal provider training. Rates Program, reforms that took effect in early 2014 with the po-
of off-label medication use in the pediatric population contin- tential to improve health care accessibility for children. In July
ue to increase and are often used in the management of acute of the same year, the US Department of Health and Human
agitation in the pediatric population. The current literature will Services awarded over 54 million dollars in ACA funding to
be reviewed and summarized for application in emergent support the development of mental health services in 47 states
treatment settings. Overall, evidence to inform best practice and Puerto Rico, and a survey published by the National
is limited, leading to opportunities for innovation in health Alliance of Mental Illness in December 2014 demonstrated
care delivery, the development of new research aims, and dis- that 29 states and the District of Columbia increased funding
cussion of challenging clinical dilemmas. for mental health services for the fiscal year 2015 [5]. In spite
of these advances, however, it is estimated that as few as one
in six youth with mental health problems receive needed treat-
Keywords Pediatric . Suicide . Agitation . Chemical ment [6]. More than 3000 general inpatient psychiatric beds
restraint . Psychiatric emergency were lost between 2009 and 2012, and the average wait time
for an appointment with a child and adolescent psychiatrist is
estimated to be nearly 8 weeks [5]. These waits are likely due
to the critical workforce shortage in child and adolescent psy-
This article is part of the Topical Collection on Complex Medical- chiatry. The American Medical Association estimates that as
Psychiatric Issues of 2012, there are only 8300 practicing child and adolescent
psychiatrists in the country, whereas the projected need is 30,
* Beau Carubia 000 [7, 8].
Beau.carubia@childrenscolorado.org In the context of an overwhelmed and shifting mental
health system of care, pediatric patients are presenting to
emergency rooms in psychiatric crisis in increasing numbers.
1
Department of Psychiatry, University of Colorado, Aurora, CO, USA Updated analysis of the National Hospital Ambulatory
2
Psychiatric Emergency Service, Childrens Hospital Colorado, Medical Care Survey data demonstrates the percentage of
Aurora, CO, USA emergency department (ED) visits for psychiatric conditions
3
B. Harrison Levine, MD, Inc., Denver, CO, USA increased from 4.4 % in 2001 to 7.2 % in 2011. Among
41 Page 2 of 8 Curr Psychiatry Rep (2016) 18:41

children, those between the ages of 12 and 17 account for found that the frequency of visits to the emergency room by
the majority of psychiatric ED visits, and children who suicidal patients has increased in recent years from 0.8 to 1.5
are publicly insured or have no insurance are four times per 1000 in the USA from 1992 to 2001 [2224]. With over
more likely to be seen for a psychiatric emergency than one million adolescents utilizing the emergency room as their
those with private insurance [9, 10]. The volume of primary source of medical care, clinical encounters in the
child psychiatric emergency room visits tends to vary emergency room present important opportunities to identify
with the school calendar, with fewer visits occurring dur- patients at risk for suicide that would not otherwise be seen by
ing the summer months, and presentations tend to occur medical or mental health professionals. Additionally elevating
most often in the evening [6, 11]. One Canadian study the importance of suicide screening at the time of an emergen-
demonstrated that acuity ratings for pediatric patients pre- cy room encounter is the knowledge that a significant propor-
senting in psychiatric crisis has decreased between 2002 tion of adolescents that go on to complete suicide seek med-
and 2012, a finding replicated during a 2010 review of ical attention within the year prior to their attempts [2527].
ED pediatric psychiatric services in Virginia, suggesting While the public health and clinical concern for youth suicide
that patients are utilizing the emergency department as a compel pediatric providers to seize opportunities for potential-
way to have their non-urgent mental health needs ad- ly lifesaving intervention in the emergency room setting, sys-
dressed because they are unable to access care in an al- tems of care are also required to respond to requirements of the
ternate setting [12, 13]. Length of stay (LOS) in EDs Joint Commission on Accreditation of Healthcare
averages about 5 hours, consistently exceeding pediatric Organizations to conduct suicide risk assessments with pa-
ED visits for other conditions by over 1 hour. Longer tients that present with emotional or behavioral problems [28].
LOS is associated with patients leaving before receiving
assessment or critical intervention for their psychiatric
crisis; key factors associated with greater LOS are the Attitudes and Beliefs About Suicide Screening
need for transfer and psychiatric admission. Length of
stay also varies geographically and is negatively correlat- Despite the importance of identifying youth at risk for suicide
ed with the availability of inpatient child psychiatric beds in the emergency room, studies show that suicide screening is
[14, 15]. There is a strong consensus among national pro- completed by only a minority of general and pediatric emer-
fessional organizations, including the Institute of gency room providers [23, 29]. Surveys of emergency room
Medicine, the American Academy of Pediatrics, and the providers, including both physicians and nurses, demonstrate
National Institute of Mental Health, that standards of care their awareness about the high prevalence of pediatric depres-
and provider education are needed to address this sion and suicidality and the need for suicide screening, but
burgeoning clinical need; however, clinical practice is cur- they often cite concerns regarding patient acceptability of
rently heterogeneous, often based on available expertise screening, time constraints, and lack of training about suicide
and resources, and lacks evidence base to inform best screening as barriers for incorporating such screening into
practice [16, 17, 18]. Pediatric patients present to EDs routine clinical practice [29, 30].
with varied chief complaints and psychiatric crises, the Despite the concerns of providers, surveys of patients and
most common being depression, suicidal ideation, and vi- caregivers presenting to emergency rooms with chief com-
olent behaviors [19]. plaints that were both psychiatric and non-psychiatric in na-
ture consistently report high levels of acceptability of mental
health and suicide screening [27, 31]. A qualitative study of
Clinical Care: Suicide pediatric patients that were screened for suicide risk noted that
screening was a way Bfor patients to feel known, heard and
According to the results of the 2013 National Youth Risk understood^ by an unbiased listener. They also described
Behavior Survey, 17 % of a sample of over 13,000 high school screening as an important way for Bindividuals who were at
students reported having Bseriously considered attempting risk (to) receive help that would prevent later suicidal
suicide^ during the 12 months prior to the survey. Nearly behavior.^ [32].
14 % of students reported making a suicide plan, and 8 % a Studies of feasibility also suggest that provider-perceived
suicide attempt [20]. Suicide is the second leading cause of barriers may be overstated. For example, a 2007 study con-
death for youth in the USA resulting in over 2000 deaths in the ducted in a pediatric emergency room in an urban, tertiary care
1019 age group in the year 2012 [21]. The emergency room hospital analyzed the addition of a self-administered, comput-
is a crucial environment for suicide screening, intervention, erized suicide screening to patient care. The screening was
and prevention to occur. Studies have shown that the children completed in parallel to medical assessment and treatment,
seeking health and mental health ED services are at high risk and providers reported that the screenings did not impede their
for psychiatric problems including suicidality. One study ability to complete their clinical work [27].
Curr Psychiatry Rep (2016) 18:41 Page 3 of 8 41

Suicide Risk Assessment Tools Clinical Care: Agitation

Multiple factors should be considered in selecting a suicide As previously mentioned, pediatric patients present to EDs
risk screening tool for use in the emergency room. Screeners with various psychiatric crises, including depression, suicidal
should not only be valid and reliable and have high sensitivity ideation, and violent behaviors [19]. When these behaviors
and specificity for identifying those youth at risk but should threaten the safety of the patient or others, acute intervention
also be efficient and require minimal training for administra- becomes necessary. The desired outcome in the management
tion and interpretation of results. The evidence base to support of an agitated youth is the prevention of harm to self or others,
the preferential use of one screening tool remains limited. including family members and ED staff [38, 39]. As described
Below is an overview of several pediatric screening tools that by Sonnier et al., Bacute agitation is defined as a state of
have been used in ED settings. behavioral dyscontrol that will likely result in harm to the
The Reynolds Suicide Ideation Questionnaire (SIQ) is a patient or healthcare workers without intervention^ [40]. A
screening tool that has been studied in clinical and school- practitioner should strive to use the least restrictive means
based samples of youth and has established psychometric possible to provide this level of safety to a youth, but when
properties in identifying the frequency and severity of suicidal this is not possible, physical and/or chemical restraint may
ideation [33, 34]. It is often the criterion standard against become necessary.
which other rating scales are measured to determine their va- The use of restraint in the pediatric emergency setting has
lidity. The SIQ is a self-report measure and has the advantage become more common. A retrospective observational study,
of the availability of normative scores to aid in the interpreta- conducted over two consecutive years, looked at youth who
tion of results. The SIQ is available in two versions for youth: presented to an urban pediatric ED requiring an emergent
a 30-item questionnaire for adolescents 15 years and older psychiatric evaluation (n = 1125). Investigators found that
(SIQ), and a 15-item questionnaire for those under the age 6.8 % of the youth required a restraint during their evaluation,
of 15 (SIQ-JR). It is estimated that the measure can be deliv- of which 49 % were physical restraint, 25 % medication re-
ered in 10 minutes or less and is recommended that for suc- straint, and 26 % both physical and medication restraint. In
cessful administration and interpretation, providers have spe- this study, out-of-control behaviors were correlated with re-
cialty training and experience in the use of clinical behavioral straint use [41]. Similarly, a retrospective chart review by
assessment instruments. Baeza et al. examined the management of Baggressive events
The Columbia Suicide Severity Rating Scale is another requiring an intervention^ in an adolescent inpatient psychi-
screener that has been specifically studied in youth presenting atric unit over a 2-year period. Twenty-eight percent of the
to the emergency room with a psychiatric chief complaint adolescents had at least one aggressive event recorded, and
[35, 36]. It is a semi-structured interview that not only iden- in 95.6 % of the cases, the first-line intervention used was
tifies current suicide risk but also appears to have validity in pharmacologic, specifically 29.5 % antipsychotic alone,
predicting future return to the ED with suicidal ideation or 38.8 % combination or alternation of antipsychotics and sed-
post suicide attempt. The length of time to complete the as- atives, 23.3 % antihistamines, and 5.6 % sedative alone [42].
sessment is variable and dependent upon responses. Training A recent paper discussing the rising trends in antipsy-
is required to administer this scale; computer-based training is chotic prescriptions for youth with behavioral problems es-
available. timated an approximate twofold to fivefold increase in off-
The Ask Suicide-Screening Questions (ASQ) may be label use of antipsychotics in preschool-aged children over
particularly useful in pediatric ED settings as it is both the past 1015 years [43]. Common off-label uses of anti-
psychometrically sound and brief. This four-item ques- psychotics in children and adolescents include treatment of
tionnaire was developed from a set of 17 candidate disruptive behaviors, aggression in typically developed and
questions. The responses of 524 youth to the candidate developmentally delayed children, oppositional defiant dis-
questions were compared via logistic regression analysis order (ODD), conduct disorder (CD), posttraumatic stress
models to the results of the lengthier SIQ to determine disorder (PTSD), attention-deficit hyperactivity disorder
which four-question combination most accurately (ADHD), sleep disorders, and depressive disorders [44,
assessed suicide risk. The ASQ appeared not only to 45]. In a recent national survey sent to 1600 randomly se-
have good sensitivity, specificity, and predictive values lected child and adolescent psychiatrists, 36 % reported
but was estimated to take less than 2 minutes to admin- occasional off-label use of second generation antipsy-
ister [37]. The instrument has the advantage of being chotics (SGAs), 65 % felt the best option for management
studied with both psychiatric patients and those present- of aggressive behaviors in Autism Spectrum Disorder
ing to the emergency room with medical or surgical (ASD) were SGAs, and 29 % believed SGAs were the best
complaints. Further study is necessary to establish the option for management of children with aberrant behaviors,
best procedures for administering this screener. including assaultiveness and destruction of property [46].
41 Page 4 of 8 Curr Psychiatry Rep (2016) 18:41

Considerations for Pharmacologic Management favorable number needed to treat (NNT) of 3 (compared to 4
of Agitation for both lithium and stimulants). In the reviewed studies com-
paring risperidone to placebo, the mean effect size (ES) for
Given the high prevalence of the use of emergency medica- aggression was 0.72 compared to 0.60 for stimulants and 0.47
tions in the pediatric population, it is imperative that practi- for mood stabilizers. In the one, small study evaluating halo-
tioners are afforded the ability to make evidence-based treat- peridol versus placebo, the ES was noted to be 0.83 [48].
ment selections in the management of behavioral emergen- Building from the T-MAY guidelines, a multidisciplinary
cies. First, it is important to consider the evidence base for Canadian consensus group also conducted a systematic re-
the most commonly used medication classes. view with the aim of developing evidence-based treatment
Several systematic reviews (including meta-analyses) and guidelines for oppositional behavior, conduct problems, and
guidelines have been published regarding the evidence-based aggression in children and adolescents [49, 51]. Studies
treatments for acute agitation in the pediatric population in the were identified for risperidone, quetiapine, haloperidol,
last 5 years. Through a steering group of national experts, the valproate, lithium, and carbamazepine versus placebo in chil-
Resource for Advancing Childrens Health (REACH) Institute dren diagnosed with ODD or CD with or without ADHD
and the Center for Education and Research on Mental Health [49]. Valproate, lithium, and carbamazepine displayed little
Therapeutics (CERT) developed the Treatment of positive effect [49]. The authors also found minimal
Maladaptive Aggression in Youth (T-MAY) guidelines [47, supporting evidence for the use of haloperidol in the treatment
48]. This group identified 28 placebo-control studies, 5 fo- of aggression in youth with CD and recommended strongly
cusing on ASD, and the others on ODD, ADHD, and CD, that against its use [49, 51]. One small study evaluating the
directly measured aggression and evaluated a pharmacologic effectiveness of quetiapine on aggression in adolescents with
intervention [48]. They found the SGAs had the most CD with or without ADHD found a standard mean difference

Table 1 FDA-approved first-


and second-generation antipsy- Drug name Age of approval Approved clinical indication
chotics for use in the pediatric
population FGA
Chlopromazine Age 112 years Schizophrenia; bipolar disorder, type I; severe behavioral problems
(i.e., explosiveness, combativeness); hyperactive behaviors with
CDs
Haloperidol 3 years of age Severe behavioral problems and hyperactive behavior;
schizophrenia; psychosis; Tourettes syndrome
Thioridazine 5 years of age Schizophrenia
Trifluoperazine 6 years of age Schizophrenia
Thiothixene 12 years of age Schizophrenia
Molindone 12 years of age Schizophrenia
Perphenazine 12 years of age Schizophrenia
Pimozide 12 years of age Tourettes syndrome
Prochlorperazine 2 years of age Schizophrenia
and 20 lbs
Droperidol BChildren^ Agitation
SGA
Risperidone Age 516 years Autism-irritability
10 years of age Bipolar disorder, type I
13 years of age Schizophrenia
Aripiprazole Age 617 years Autism-irritability
10 years of age Bipolar disorder, type I
13 years of age Schizophrenia
Quetiapine 10 years of age Bipolar disorder, type I
13 years of age Schizophrenia
Olanzapine 13 years of age Bipolar disorder, type I; schizophrenia
Asenapine 10 years of age Bipolar disorder, type I
Paliperidone 12 years of age Schizophrenia

FGA first-generation antipsychotic, SGA second-generation antipsychotic, CD conduct disorders


Curr Psychiatry Rep (2016) 18:41 Page 5 of 8 41

ES of 1.6; however, the authors cautioned against over inter- measured. The authors concluded that risperidone has a mod-
pretation of the large effect size given the very low quality of erate effect on conduct problems and aggression in children
this study and provided a recommendation of conditional with average and sub-average IQ, with stronger evidence
against its use [49]. In trials of risperidone versus placebo, supporting its use with the sub-average IQ population [51].
the authors found a standard mean difference ES of 0.72 in Seida et al. performed a comparative effectiveness analysis
conduct problems and aggression in youth with low intelli- of studies identified through a systematic review to evaluate
gence quotient (IQ) and ODD or CD, with or without ADHD, the efficacy and safety of antipsychotic use in youth with
and a standard mean difference ES of 0.60 in disruptive and psychiatric and behavioral problems [52]. The authors eval-
aggressive behavior in youth with average IQ and ODD or uated 64 trials and 17 cohort studies. They found minimal or
CD, with or without ADHD. In this review, risperidone was insufficient evidence for all comparisons of FGAs versus pla-
the only SGA or first-generation antipsychotic (FGA) to re- cebo, FGAs versus other FGAs, and FGAs versus SGAs
ceive a recommendation of conditional in favor of use, with [52]. They did find moderate evidence for SGAs versus pla-
caution advised secondary to the potential side effect burden cebo in improvement of Clinical Global Impressions (CGI)
[49]. and decreased behavioral symptoms for disruptive behavior
Three years ago, Pringsheim et al. published a systematic disorders. In regards to tolerability, key findings included
review of SGAs for the treatment of disruptive behavior dis- olanzapine causing the highest levels of dyslipidemia and
orders in children and found weak placebo-controlled evi- weight gain and risperidone causing the most prolactin-
dence for the use of SGAs other than risperidone, and also related events [52].
found weak evidence for the use of the SGAs in youth with Another interesting FGA, droperidol, with a well-known
average IQs [50]. Building off this initial review, Pringsheim FDA black box warning for proarrhythmic effects secondary
et al. conducted another systematic review and meta-analysis to potential QT prolongation was recently reviewed in the
evaluating trials of antipsychotics, lithium, and anticonvul- adult literature [53]. The authors found doses up to 10 mg to
sants in the treatment of youth with ADHD, ODD, and CD be efficacious and safe for sedation and as an intervention for
with aggression and conduct problems [51]. In accordance agitation [53]. The American Academy of Emergency
with the Canadian review, the authors found limited empirical Medicine recently released a position statement on droperidol
support for the use of haloperidol, quetiapine, and mood sta- use in the ED setting, finding that Bdroperidol is an effective
bilizers. In the one study of thioridazine in youth with sub- and safe medication in the treatment of nausea, headache, and
average IQ and ADHD or CD, no primary outcome was agitation^ [53]. Swank et al. conducted a chart review over

Table 2 Pharmacologic agents to


consider for pediatric chemical Drug class/drug name Administration routes Initial dose rangea
restraint
FGA
Haloperidol PO, IM, IV PO: 0.5 to 5 mg
IM: 0.05 to 0.15 mg/kg; max 5 mg/dose
Droperidol IM, IV IM/IV: 0.030.07 mg/kg/dose up to max 2.5 mg/dose
without cardiac monitor
Chlorpromazine PO, IM PO/IM: 0.55 mg/kg/dose
SGA
Risperidone PO, ODT PO: 0.252mg
ODT: 0.252 mg
Olanzapine PO, ODT PO: 2.55 mg
ODT: 2.55 mg
Benzodiazepine
Lorazepam PO, IM, IV PO/IM/IV: 0.050.1 mg/kg/dose to max dose 2 mg/dose
Midazolam PO, IM, IN PO: 0.250.5/mg/kg/dose; max 20 mg
IM: 0.10.15 mg/kg/dose; max 10 mg
IN: 0.20.3 mg/kg to max of 10 mg
Antihistamine
Diphenhydramine PO, IM PO/IM: 1 mg/kg/dose to max 50 mg/dose

PO oral, IM intramuscular, IV intravenous, ODT oral disintegrating tablet, IN intranasal


a
Lexi-Comp Online, Hudson, Ohio: Lexi-Comp Inc.; 2015; Sept 26th, 2015. All doses should be determined
individually based on weight, age, and pertinent medical conditions
41 Page 6 of 8 Curr Psychiatry Rep (2016) 18:41

32 months for droperidol use in the ED setting for patients Suicide screening and prevention is also on the fore-
<21 years of age [54]. They found that 86 % of the identified front of the minds of pediatric providers as clinical en-
cases were given droperidol for the management of agitation counters in the emergency room present important op-
(mean dose = 4 mg). The use of droperidol demonstrated portunities for intervention. Developing the evidence ba-
86.6 % effectiveness in controlling symptoms, and they found se for accurate and efficient screening and intervention
no sign of arrhythmias in any patient [54]. is an important area that requires further investigation.
There is little evidence in the literature supporting the use Promising work in this area includes the Emergency
of benzodiazepines to target agitation in the pediatric popula- Department Screen for Teens at Risk for Suicide (ED-
tion; however, it is largely known that these agents have pow- STARS), a national, multi-site collaboration funded by
erful sedation and anxiolytic properties, which may aid in the National Institute of Mental Health whose aim is to
rapid sedation of an agitated youth [39]. Similarly, there is develop a computer-based screening tool which will aid
also no empirical evidence for the use of antihistamines our ability to effectively assess and stratify suicide risk
targeting aggression or agitation in youth [42]. in our adolescent patients. This project is currently
It is also important to consider current Federal Drug ongoing.
Administration (FDA) approvals for medications commonly In the management of behaviors placing a patient at risk of
used to treat aggressive behavior in children. As shown in harm to self or others, a practitioner has three main tools that
Table 1, only chlopromazine, haloperidol, droperidol, risperi- may be deployed: behavioral de-escalation techniques, seclu-
done, and aripiprazole carry FDA indications for aggression sion, and physical and/or chemical restraint. All measures
and/or irritability, often for select subsets of the pediatric must be taken to exercise the least restrictive means possible
population. in affording safety to a patient and surrounding others [40, 45].
A summary of pharmacologic agents to consider for chem- However, when these measures fail, a more restrictive inter-
ical restraint is listed in Table 2. Risperidone has the most vention becomes imminently necessary. Such situations are
evidence supporting its use as an intervention for children fraught with a unique ethical and clinical challenge in the
with disruptive behavior disorders and comorbid agitation, day-to-day management of behavioral emergencies, the bal-
especially children with ASD or lowaverage IQ [48, ance of non-maleficence and beneficence. One must afford a
49]. No other SGAs have empirical support for their use, safe environment to the patient and staff but must also accom-
and there is limited data supporting the use of FGAs or mood plish the management of behavioral agitation and aggression
stabilizers. Given the unknown efficacy, the known side effect with the least amount of risk of harm to the patient.
burdens, and the unknown long-term risk of the use of many Compounding this dilemma may also be a change in treatment
or all of these agents, a practitioner must remain conservative culture with more reliance on chemical restraint rather than
in the use of these agents as a chemical restraint. physical restraint. This shift in management approach is likely
the result of deaths of children that occurred and were publi-
cized in the late 1990s that had potential links to physical
Conclusions restraint. Those tragic events led to changes in the regulations
governing the use of restraints from the Centers for Medicare
Children and adolescents are presenting to emergency rooms and Medicaid Services, as well as the Joint Commission for
in psychiatric crisis in increasing numbers, and just as the the Accreditation of Hospital Organizations [18]. Given this
cause for this trend is likely multi-factorial, so must be our trend, it is critical that we develop a more robust evidence base
professional response to address this burgeoning clinical need. for the use of pharmacologic agents in these situations.
Standards of care and evidence-based models for practice are And, perhaps most important for our ability to compe-
often lacking, and our ability to build our collective knowl- tently address the psychiatric clinical needs of the emer-
edge will be enhanced by our use of common definitions. One gency room setting, including the assessment and treat-
important distinction to make will be clarifying the difference ment of pediatric patients that present with depression,
between what constitutes Burgent^ and Bemergent^ condi- suicidality, and agitation, is training and education that
tions. Diverting non-emergent patients from emergency equips pediatric providers with the requisite skills and
rooms is one possible approach to address the issue of over- knowledge, thereby extending the reach of a limited spe-
crowding. Indeed, novel programs are being developed and cialty workforce. The American Association for
piloted across the country, such as the School Based Referral Emergency Psychiatry Education Committee has devel-
Program to the Urgent Evaluation Service (UES) at oped a model training curriculum, content which may
Maimonides Medical Center in Brooklyn, New York, whose serve as a useful template for training our colleagues in
aim is to collaborate with school providers in the diversion of pediatrics and emergency medicine in the proper screen-
non-emergent referrals for urgent, same-day evaluations in an ing and assessment of suicidal behavior and the treatment
outpatient setting [55]. of agitation and aggression in pediatric populations [56].
Curr Psychiatry Rep (2016) 18:41 Page 7 of 8 41

Compliance with Ethical Standards 15. Case SD, Case BG, Olfson M, et al. Length of stay of pediatric
mental health emergency department visits in the United States. J
Conflict of Interest Amy Becker, Beau Carubia, and B. Harrison Am Acad Child Adolesc Psychiatry. 2011;50(11):11109.
Levine declare that they have no conflict of interest. 16. Dola MA, Fein JA, The Committee on Pediatric Emergency
Medicine. Technical reportpediatric and adolescent mental
Human and Animal Rights and Informed Consent This article does health emergencies in the emergency medical services system.
not contain any studies with human or animal subjects performed by any Pediatric. 2011;127:e135666.
of the authors. 17. Janssens A, Hayen S, Walraven V, et al. Emergency psychiatric care
for children and adolescents: a literature review. Pediatr Emerg
Care. 2013;29:104150.
18. Chun TH, Katz ER, Duffy SJ, Gerson RS. Challenges of managing
pediatric mental health crises in the emergency department. Child
Adolesc Psychiatr Clin N Am. 2015;24(1):2140. Very good
References review/guide for clinical use; reviews suicide/risk assessment,
safety planning, physical restraints and mandated regulatory
guidelines, chemical restraints, and comments on care of the
Papers of particular interest, published recently, have been ASD and developmentally delayed population.
highlighted as: 19. Liu S, Ali S, Rosychuk RJ, Newton A. Characteristics of children
Of importance and youth who visit the emergency department for a behavioural
disorder. J Can Acad Child Adolesc Psychiatry. 2014;23(2):1117.
Of major importance
20. U.S. Department of Health and Human Services. Youth Risk
Behavior Surveillance System; Trends in the Prevalence of
1. Kieling C, Baker-Henningham H, Belfer M, et al. Global Mental Suicide-Related Behavior National YRBS: 1991-2013. Centers
Health 2; Child and adolescent mental health worldwide: evidence for Disease Control and Prevention, Morbidity and Mortality
for action. Lancet. 2011;378(9801):151525. Weekly Report; June 13, 2014.
2. Merikangas KR, He J, Burstein M, et al. Lifetime prevalence of 21. Heron, M. Deaths: Leading Causes for 2012. Centers for Disease
mental disorders in US adolescents: results from the National Control and Prevention, National Vital Statistics Reports; August
Comorbidity Study-Adolescent Supplement (NCS-A). J Am Acad 31, 2015.
Child Adolesc Psychiatry. 2010;49(10):9809. 22. Larkin GL, Beautrais AL. Emergency departments are
3. U.S. Department of Health and Human Services. Mental Health underutilized sites for suicide prevention. Crisis. 2010;31(1):16.
Surveillance Among Children-United States, 2005-2011. In: 23. Chun TH, Duffy SJ, Linakis J. Emergency department screening for
Centers for Disease Control and Prevention, Morbidity and adolescent mental health disorders: the who, what, when, where and
Mortality Weekly Report; May 17, 2013. 2013. why and how it could and should be done. Clin Pediatr Emerg Med.
4. Mental Health America. Parity of Disparity: The State of Mental 2013;14(1):311.
Health in America. 2015. 24. Newton AS, Hamm MP, Bethell J, et al. Pediatric-related presenta-
5. National Alliance on Mental Illness. State Mental Health tions: a systematic review of mental health care in the emergency
Legislation 2014: Trends, Themes & Effective Practices. 2014. department. Ann Emerg Med. 2013;56(6):64959.
6. Ali S, Rosychuk RJ, Dong KA, et al. Temporal trends in pediatric 25. OMara RM, Hill RM, Cunninghom RM, King C. Adolescent and
mental health visits: using longitudinal data to inform emergency parent attitudes toward screening for suicide risk and mental health
department heath care planning. Pediatr Emerg Care. 2012;28:620 problems in the pediatric emergency room. Pediatr Emerg Care.
5. 2012;28:62632.
7. American Academy of Child and Adolescent Psychiatry. Child and 26. Horowitz LM, Bridge JA, Pao M, Edwin B. Screening youth for
Adolescent Psychiatry Workforce Crisis: Solutions to Improve suicide risk in the medical setting. Am J Prev Med. 2014;47(3S2):
Early Intervention and Access to Care. May 2013. Updated work- S1705.
force summary prepared by AACAP. 27. Williams JR, Ho ML, Grupp-Phelan J. The acceptability of mental
8. American Academy of Child and Adolescent Psychiatry. AACAP health screening in a pediatric emergency department. Pediatr
Workforce Fact Sheet 2012. Updated workforce summary Emerg Care. 2011;27:6115.
prepared by AACAP. 28. The Joint Commission on Accreditation of Health Care
9. Simon AE, Schoendorf K. Emergency department visits for mental Organizations. A follow-up report on preventing suicide: Focus
health conditions among US children, 2001-2011. Clin Pediatr. on medical/surgical units and the emergency department. The
2014;53(14):135966. Joint Commission Sentinel Event Alert; November 17, 2010.
10. Pittsenbarger ZE, Rebekah M. Trends in pediatric visits to the emer- 29. Betz ME, Sullivan AF, Manton AP, Espinola JA, et al. Knowledge,
gency department for psychiatric illness. Acad Emerg Med. attitudes and practices of emergency department providers in the
2014;21:2530. Updated summary of emergency department care of suicidal patients. Depress Anxiety. 2013;30(10):100512.
trends. 30. Cronholm PF, Barg FK, Pailler ME, Wintersteen MB, et al.
11. Lueck C, Kearl L, Lam CN, Cladius I. Do emergency pediatric Adolescent depression: views of health care providers in a pediatric
psychiatric visits for danger to self or others correspond to times emergency department. Pediatr Emerg Care. 2010;26:1117.
of school attendance? Am J Emerg Med. 2015;33:6824. 31. Horowitz L, Ballard E, Teach SJ, Bosk A, et al. Feasibility of
12. Mapellli E, Black T, Doan Q. Trends in Pediatric Emergency screening patients with nonpsychiatric complaints for suicide risk
Department Utilization for Mental Health-Related Visits. J Pediatr in a pediatric emergency department: a good time to talk? Pediatr
2015;167(4):90510. Emerg Care. 2010;26(11):78792.
13. Brown JF, Schubert C. An examination of emergency department 32. Ballard ED, Bosk A, Snyder D, Pao M, Bridge JA. et at. Patients
psychiatric services. J Behav Health Serv Res. 2010;37(4):41226. opinions about suicide screening in a pediatric emergency depart-
14. Grover P, Lee T. Dedicated pediatric behavioral health unit: serving ment. Pediatr Emerg Care. 2012;28(1):348.
the unique and individual needs of children in behavioral health 33. Reynolds WM, Mazza J. Assessment of suicidal ideation in inner-
crisis. Pediatr Emerg Care. 2013;29:2002. city children and young adolescents: reliability and validity of the
41 Page 8 of 8 Curr Psychiatry Rep (2016) 18:41

suicidal ideation questionnaire-JR. School Psych Rev. 1999;28(1): and management. Pediatrics. 2012;129(6):e156276. Large sys-
1730. tematic review providing evidence-based clinical guidelines for
34. Abdel-Khalek A, Lester D. The psychometric properties and corre- engagement of family and key principles initial assessment and
lates of the Reynolds Suicide Ideation Questionnaire with Kuwaiti diagnosis.
and American students. Arch Suicide Res. 2007;11:30919. 48. Scotto Rosato N, Correll CU, Pappadopulos E, et al. Treatment of
35. Gipson PY, Agarwala P, Opperman MA, Horowitz A, Cheryl K. maladaptive aggression in youth: CERT guidelines II. Treatments
Columbia-Suicide Severity Rating Scale: predictive validity with and ongoing management. Pediatrics. 2012;129(6):e157786.
adolescent psychiatric emergency patients. Pediatr Emerg Care. Large systematic review and resulting evidence based recom-
2015;31:8894. Study of suicide risk screening tool conducted mendations for treatment and management of aggressive
in the emergency room with pediatric patients. youth. Reviews efficacy and tolerability.
36. Posner K, Brown GK, Stanley B, Brent D, et al. The Columbia- 49. Gorman DA, Gardner DM, Murphy AL, et al. Canadian guidelines
Suicide Severity Rating Scale: internal validity and internal consis- on pharmacotherapy for disruptive and aggressive behaviour in
tency findings from three studies with adolescents and adults. Am J children and adolescents with attention-deficit hyperactivity disor-
Psychiatry. 2011;168(12):126677. der, oppositional defiant disorder, or conduct disorder. Can J
37. Horowitz LM, Bridge JA, Teach SJ, Ballard E, et al. Ask Suicde- Psychiatry. 2015;60(2):6276. Large systemic review from
Screening Questions (ASQ): a brief instrument for the pediatric Canada for various medications; rates quality of evidence, mag-
emergency department. Arch Pediatr Adolesc Med. 2012;166(12): nitude of benefit, side effect burden, and strength of
11706. Development of brief suicide screening tool for use in recommendation.
the emergency room setting. ED-STARS building on this work. 50. Pringsheim T, Gorman D. Second-generation antipsychotics for the
38. Adimando AJ, Poncin YB, Baum CR. Pharmacological manage- treatment of disruptive behaviour disorders in children: a systematic
ment of the agitated pediatric patient. Pediatr Emerg Care. review. Can J Psychiatry. 2012;57(12):7227.
2010;26(11):85660. 51. Pringsheim T, Hirsch L, Gardner D, Gorman DA. The
39. Marzullo LR. Pharmacologic management of the agitated child. Pharmacological Management of Oppositional Behaviour,
Pediatr Emerg Care. 2014;30(4):26975. Provides practical as- Conduct Problems, and Aggression in Children and Adolescents
sessment and treatment principles for providers managing ag- With Attention-Deficit Hyperactivity Disorder, Oppositional
itation in emergent setting. Defiant Disorder, and Conduct Disorder: A Systematic Review
40. Sonnier L, Barzman D. Pharmacologic management of acutely ag- and Meta-Analysis. Part 2: Antipsychotics and Traditional Mood
itated pediatric patients. Pediatr Drugs. 2011;13(1):110. Stabilizers. Can J Psychiatry. 2015;60(2):5261. Large systemic
41. Dorfman DH, Mehta SD. Restraint use for psychiatric patients in review and meta-analysis from Canada for antipsychotics and
the pediatric emergency department. Pediatr Emerg Care. mood stabilizers; rates quality of supporting evidence and po-
2006;22(1):712. tential effect size.
42. Baeza I, Correll CU, Saito E, et al. Frequency, characteristics and 52. Seida JC, Schouten JR, Boylan K, et al. Antipsychotics for children
management of adolescent inpatient aggression. J Child Adolesc and young adults: a comparative effectiveness review. Pediatrics.
Psychopharmacol. 2013;23(4):27181. 2012;129(3):e77184. Systematic review that compares 1st and
43. Harrison JN, Cluxton-Keller F, Gross D. Antipsychotic medication 2nd generation antipsychotics within own class and across
prescribing trends in children and adolescents. J Pediatr Health classes.
Care. 2012;26(2):13945. 53. Perkins J, Ho JD, Vilke GM, DeMers G. American academy of
44. Penfold RB, Stewart C, Hunkeler EM, et al. Use of antipsychotic emergency medicine position statement: safety of droperidol use
medications in pediatric populations: what do the data say? Curr in the emergency department. J Emerg Med. 2015;49(1):917.
Psychiatry Rep. 2013;15(12):426. 54. Szwak K, Sacchetti A. Droperidol use in pediatric emergency de-
45. Masters KJ, Bellonci C, Bernet W, et al. Practice parameter for the partment patients. Pediatr Emerg Care. 2010;26(4):24850.
prevention and management of aggressive behavior in child and 55. Alvarado G and Logan Hegg. Responding to the Needs of Students
adolescent psychiatric institutions, with special reference to seclu- in Crisis. Managing Psychiatric Emergencies in Children and
sion and restraint. J Am Acad Child Adolesc Psychiatry. 2002;41(2 Adolescents. NYU School of Medicine Post-Graduate Medical
Suppl):4S25S. School. March 9, 2014.
46. Rodday AM, Parsons SK, Correll CU, et al. Child and adolescent 56. Brasch J, Glick RL, Cobb TG, Janet R. Residency Training in
psychiatrists' attitudes and practices prescribing second generation Emergency Psychiatry: A Model Curriculum Developed by the
antipsychotics. J Child Adolesc Psychopharmacol. 2014;24(2):90 Education Committee of the American Association for
3. Emergency Psychiatry. Acad Psychiatry. 2004;28:95103.
47. Knapp P, Chait A, Pappadopulos E, et al. Treatment of maladaptive Comprehensive curriculum, useful template for training pro-
aggression in youth: CERT guidelines I. Engagement, assessment, grams across pediatric health care specialties and disciplines.

Das könnte Ihnen auch gefallen