#NEET model Questions

#Proteins

1. Most abundant ECM protein-.

2. Most abundant protein in the body
3. Largest protein in the body
4. Major type of collagen in bones.
5. Major type of collagen in cartilage..
6. Major collagen in Basement membrane.
7. Most abundant collagen
8. Major collagen type in large arteries..
9. The repeating amino acid in Collagen
10. The number of amino acid residue per turn of alpha chain of collagen..
11. Total number of amino acids in single polypeptide chain of collagen..
12. The direction of turn of triple helix
13. Quarter staggered arrangement is due to ..association of triple helix.
14. The site of synthesis of collagen-(organelle) and .(cell)
15. Glycosylation protein of collagen inside..of fibroblast.
16. Triple helix is formed inside..of Fibroblast.
17. Quarter staggered arrangement is formed in .
18. Coenzymes of Prolyl and Lysyl Hydroxylase..
19. The amino acid residue that is hydroxylated(in collagen)
20. Oxidative deamination of is carried out
byenzyme,require..(mineral)
21. Covalent crosslinks by..(reaction)of (amino
acid residues)
22. Match the following,Disease with type of Collagen/Enzyme
i. Osteogenesis Imperfecta a) Lysyl Oxidase
ii. Chondrodysplasia b) Type IV
iii. Menke's Disease c) Type II
iv. Dystrophic Epidermolysis bullosa d) Type I
v. Alport's disease e) Type VII
#EDS

23. Most common EDS is ..

24. MC EDS affect ..type Collagen.
25. Most serious EDS is.affect .type Collagen
26. Tenascin X defect seen in ..EDS (.type EDS)
27. Write the type of collagen affected and the Villefranche Classification of EDS for the
following
i. Type I EDS-Type I & V Collagen./Classical EDS.(one is done for u)
ii. Type II EDS-/
iii. Type III EDS-/
iv. Type IV EDS-/.
v. Type V EDS./..
28. The pathognomonic of Alports Syndrome is..
29. ..aa present in collagen is not seen in Elastin
 30. Cross links present in Elastin is ..formed from .(aa) by
..(enzyme)
31. Number of types of Elastin is
32. Say true or false
i. Elastin has no triple helix-
ii. Elastin is a Glycoprotein-
iii. Gly-X-Y repeats are absent in Elastin-
33. William Beuren Syndrome is due to
34. The structural component of Microfibrils.
35. Fibrillin -1 is mutated in ..
36. Fibrillin -2 is mutated in ..
37. Ghents Criteria is to classify.
38. Alpha helix coils are present in .(Collagen/Keratin/Elastin)
39. Epidermolysis Bullosa Simplex is due to mutn in genes for.(Type VII
Collagen/Type 5&4 Keratin)
40. Major protein of basal laminas..
41. RGD sequence is present .(Laminin/Entactin)
42. Molecular chaperones are mostly..
43. Enzymes that assist protein folding.

#Read page 65 to 70 Self assessment and review of Biochemistry 2/e to answer Qns 1 to 43

#Amino Acids Is a must learn topic esp Classification /Urea Cycle/Transamination/Specialised

pdts from Tyrosine,Trp,Glycine,Cysteine,Serine/polyamines/Tests in amino acidurias/Entry of
amino acids to TCA Cycle.

#Questions are innumerable and difficult to cover all ,so I m posting some important tables for
easy revision.