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PleasenotethattheDavosDeclarationoncombatingAMRisnowhostedbytheInternationalFederationofPharmaceuticalManufacturers
Associations(IFPMA),withfollowupworkledbythatorganisation.Pleaseseetheirwebsiteatwww.ifpma.orgformoredetailsandthelatest
iterationoftheDeclarationandthesubsequentRoadmapdocument,orcontactinfo@ifpma.org.

DeclarationbythePharmaceutical,BiotechnologyandDiagnosticsIndustriesonCombatingAntimicrobialResistance

OnJanuary21,2016,theDeclarationbythePharmaceutical,BiotechnologyandDiagnosticsIndustriesonCombatingAntimicrobialResistancewas
launchedataneventattheWorldEconomicForuminDavos,Switzerland.

WhenpublishedinJanuary2016,theDeclarationhadbeendrafted,agreedandsignedby85companiesandnineindustryassociationsfromacross
theglobalpharmaceutical,diagnosticsandbiotechnologyindustries.AsofApril1st,2016,atotalof98companiesand11industryassociationsin21
countrieshaveaddedtheirsignaturestoit.

IntheDeclaration,signatorycompaniescallongovernmentstoworkwiththemtodevelopnewandalternativemarketstructuresthatprovidemore
dependableandsustainablemarketmodelsforantibiotics,andtocommitthefundsneededtoimplementthem.Thesemechanismsareneededto
provideappropriateincentives(coupledwithsafeguardstosupportantibioticconservation)forcompaniestoinvestinR&Dtoovercomethe
formidabletechnicalandscientificchallengesofantibioticdiscoveryanddevelopment.Theseincludemechanismstoensurethat,whereappropriate,
thepricingofantibioticsmoreadequatelyreflectsthebenefitstheybringandnovelpaymentmodelsthatreducethelinkbetweentheprofitabilityof
anantibioticandthevolumesold.Anintegralpartofthesemodelsisareducedneedforpromotionalactivitybycompanies.

TheDeclarationalsosetsoutacommitmenttofurtheractionondrugresistancebyitssignatories,acrossthreebroadareas:

Reducingthedevelopmentofdrugresistance.Thecompaniescommittoencouragingbetterandmoreappropriateuseofnewandexisting
antibiotics,includingthroughworkthatsupportstheantibioticstewardshipprinciplessetoutbytheWorldHealthOrganization(WHO)GlobalAction
Planonantimicrobialresistance(AMR),andviaimprovededucationofclinicians.Thissupportextendstopromotingmorejudicioususeofantibiotics
inlivestock,aspartofaonehealthapproach.
IncreasinginvestmentinR&Dthatmeetsglobalpublichealthneeds.Recognisingtheneedtoincreaseresearchintonewantibiotics,
diagnostics,vaccinesandotheralternativetreatments,thecompaniescommittoacontinuationandextensionofcollaborativeinitiativesbetween
industry,academiaandpublicbodiestoimprovehowR&Dinthefieldisdoneandprovidegreateropportunitiesforthescientificbarrierstoantibiotic
discoverytobeovercome.
Improveaccesstohighqualityantibioticsforall.Inlightofthegapsthatremaininglobalaccesstoourexistingantibioticsandvaccines,andthe
importanceofensuringthatnewgenerationsofproductsareavailabletoallthosewhoneedthem,thesignatoriescommittosupportinginitiatives
aimedatensuringaffordableaccesstoantibioticsinallpartsoftheworld,atalllevelsofincome.

TheDeclarationremainsalivingdocument,withsignatoriesfreetoaddorremovetheirendorsementatanytime.

TheReviewonAntimicrobialResistanceisnotasignatorytotheDeclarationbutithasassisteditsdevelopmentandsupportsitsaims.TheReviewis
hostingtheDeclarationonitswebsiteonbehalfofthesignatorycompanies.

Readthepressnoticehere.

Readtheindustrydeclarationhere.

TheDeclarationwasfollowedinSeptember2016byaRoadmapforProgress,signedby13majorglobalpharmaceuticalcompanies,whichbuilton
theDeclarationbysettingoutmoredetailedcommitmentsbycompaniestoaddressAMRthroughactiononseveralfronts,including:

Actingonenvironmentalpollutionassociatedwithantibioticmanufacturing.
Supportingimprovedstewardshipofantibiotics.
Supportingaffordableaccesstonewandexistingantibioticsforthepatientswhoneedthem.
Increasingopencollaborationinantibioticdiscoveryefforts.