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The Infamous Willi- Prada Disease

By Josh Bracero Period 4


Willi-Prada Disease or better known as Prader Willi syndrome. It alters many different

parts of the body in many different ways. It can lead to obesity, improper digestion, diabetes, and

a loss of intelligence. It is also stated that you can get shorter if you indeed have the disease.

Not a wide known disease, with only 20,000 cases in the United States every year, it is

considered a very rare disease. This disease has the ability to alter mood swings, and also cause

hunger. Which symptoms of this start at the age of 2, which is very young for this type of

disorder. Over time, the person will have a poor growth development which will end up in a

short kid. If you get this disease at a later age you will drop height by about age 15. This disease

also leads to obesity and diabetes that emerge from the age of 2. Which can lead to more health

problems at a later age.

Prader Willi can be fatal if you do not treat it properly. It is recommended to have special

medical help after the age of 40. But if a person with the disease goes to normal doctor visits and

tends to avoid obesity, then a normal life expectancy is the same of a person without the disease.

But if the person does not obey the rules and go to regular checkups, Prader Willi can turn into

osteoarthritis or even worse: osteoporosis, which is the condition where the bones in your body

weaken and brittle. And osteoporosis is a very common disease with 3 million new cases every

year.

This disease is a recessive trait which explains why it is such a rare disease. The reason

why people get obese from this disease is because it disables the ability to feel full and causes the

person to eat more food.


Origins of the Disease

The disease was first discovered in the 1956 by 3 endocrinologists known as Andrea Prader,

Heinrich Willi, and Alexis Labhart. They noticed some abnormal behaviors in children, involving

height, weight, behavior, and sexual behaviors. This seemed suspicious at the time since there

has been no such thing before in Switzerland so the 3 endocrinologists decided to make a report

about it in the late 1960s. It eventually spread worldwide, causing everyone to know what the

disease was capable of. But it is a bigger problem today with the increasing amount of cases

every year.

Future of the Disease

So far there is no cure for this disease but there are treatments to help make the effects of the

disease for instance as stated earlier, going to normally scheduled doctors appointments will

help find any possible existing or future symptoms. Eating a healthy diet can reduce of becoming

obese and acquiring osteoporosis. Drinking milk and getting all daily nutrients will also reduce

the risk of getting the other diseases if you have Prader Willi.

Since the search for a cure is predominant, more and more children are born with the

disease which is genetic. As I said earlier, this is a recessive genetic disorder. The chances of

being born with the disease is about every 1 in every 15,000 births. Which gives and

approximate 0.00006% chance of being born with it.

My Opinions
I for one believe that this should be something that is discussed more often. Because the

effects of this disease can seriously impact someones life for the worse. Being born only to find

out that you cant tell when youre full and always being hungry is a scary feeling. Only to find

out that you can become obese in the future is a dramatic end to a never ending nightmare. I

understand that cancer and diabetes are the number one diseases that are trying to be cured. But

this disease can lead to diabetes. Which should be more looked into, since not many people have

it, but the people that have it know that they are being left out. Since this disease is claimed to

have a chance for the person to lose intellect, it brings sorrow to my eyes. My cousin has a

mental disorder that makes him lose memory fast and I can relate to those families that have to

go through their children with this disorder.

I know that we should spend money to help look for a cure for this because these kids

that were born with it have no choice to have or not, and they suffer the consequences that no

one kid should have to face. No child should be left behind in school and in this case in life.

They should have the opportunity to have a good life.

Additional Information

Willi Para is a disorder in chromosome 15, its where there are 3 different subtypes cause

the chromosome to be missing some genetic information. About 70 percent of the information

from chromosome 15 is missing which is a significant amount. A person without Willi Para gets

one normal chromosome 15 from their mom and one from their dad.

Some symptoms that are noticeable are: normal sleep deprivation, almond shaped mouth,

triangular shaped mouth delayed puberty unnatural light colored hair, and light skin color.
My Research

So for this project I spent like 5 hours looking for of this information because it took a while to

find some information that is legitimate. I watched some videos and found out that about 7,000

people have this disorder in our state, which is a lot considering the population of the state. So

my citations have all the sites that I used and looked up information on. At first I had no clue

what in the Willi Prada was, and now it really impacted me knowing some people I know have

family members that have the infamous disease. I hope to learn from this project and take it far

away.

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