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WATER and SANITATION

in Developing
Countries: Including
Health in the Equation
Millions suffer from preventable illnesses
and die every year.

M AGGIE A. MONTGOMERY
MENACHEM ELIMELECH
YALE UNIV ERSIT Y

I
mproving global access to clean drinking water hanced and services expanded through greater col-
and safe sanitation is one of the least expen- laboration between the fields of water and sanitation
sive and most effective means to improve pub- engineering and public health. Second, research-
lic health and save lives. The concept of clean ers should focus on the sustainability of water and
water and safe sanitation as essential to health sanitation services by developing strategies that ho-
is not a novel idea. In 350 B.C., Hippocrates recom- listically address the influence of the environment,
mended boiling water to inactivate impurities. The culture, and economics on the implementation and
U.S. and Central Europe, where water and sanitation long-term maintenance of treatment systems. Low-
services are nearly universal, significantly reduced cost household technologies, as opposed to central-
water-, sanitation-, and hygiene-related diseases ized systems, offer one means of addressing water
by the start of the 20th century by protecting water and sanitation needs in a more integrated and sus-
sources and installing sewage systems. However, tainable manner. Third, the obstacles to improving
in developing countries, water and sanitation ser- water and sanitation services, such as lack of invest-
vices are still severely lacking. As a result, millions ment, lack of political will, and difficulty in main-
suffer from preventable illnesses and die every year taining services, must be overcome so that these
(1). Many obstacles must be overcome to improve services can be improved and global coverage ul-
these statistics. The integration of public health into timately achieved. This will require greater col-
engineering problem solving is critical, but current laboration among the water, health, and education
efforts are insufficient. Through partnerships with sectors in conducting community-based research
local communities to implement water and sanita- and work, formulating evidence-based policies that
tion solutions that consider environmental, cultural, allow for effective investments, and focusing on de-
and economic conditions, progress toward achiev- veloping solutions that can be locally managed and
ing and sustaining global coverage of water and san- maintained.
itation services will be greatly enhanced.
In this article, we discuss three main themes Billions suffer without improved water and
about water, sanitation, and health in developing sanitation services
WORLD BANK

regions. First, water and sanitation services have Global figures that describe the lack of water and
markedly improved health and engendered many sanitation services are alarming. More than 1.1 bil-
secondary benefits. These benefits could be en- lion people do not have access to improved drink-

2007 American Chemical Society JANUARY 1, 2007 / Environmental Science & Technology n 17
FIGURE 1 health standards, such as those set forth by World
Health Organization (WHO) Guidelines for Drink-
Comparison between lack of access ing Water Quality. Rather, the term improved ac-
to improved water and sanitation and cess usually represents households that obtain
water from sources that are superior to traditional,
deaths attributable to diarrheal diseases unprotected ones. Sources that meet the definition
Adapted with permission from Ref. 1. of improved water include a household connection,
borehole, protected dug well, protected spring, or
70 25 rainwater collection (1). Connection to a public sew-
60 er or septic system or use of ventilated pit latrines

Deaths/1000 children
20
% without access

50 and some simple pit latrines qualify as improved


40 15 sanitation (1).
Figure 1 illustrates, by region, the percentage of
30 10 the population without access to improved water
20
5 and sanitation. To demonstrate how this impacts
10 health, the figure also shows number of deaths per
0 0 1000 children younger than 1 year of age that are at-
Developed countries

Eastern Asia

Latin America and the Caribbean

Northern Africa

Southeastern Asia

Western Asia

Oceania

South Asia

Sub-Saharan Africa
tributable to diarrheal diseases (1). Conditions are
most severe in sub-Saharan Africa, where 42% of the
population is without improved water, 64% is with-
out improved sanitation, and deaths due to diarrheal
diseases are greater than in any other region.
In an effort to bring global attention and resourc-
% without access to es to the problem, international organizations have
improved sanitation created several water and sanitation initiatives. The
% without access to UN, as part of its Millennium Development Goals
improved water
Number of deaths/1000
(MDGs), has set a target of halving the proportion
children <1 yr of people without access to safe drinking water and
basic sanitation by 2015 (2). WHO has declared
20052015 the decade of water, with the goal of es-
ing-water supplies (1). Lack of sanitation is an even tablishing the framework to eventually provide full
larger problem; an estimated 2.6 billion individu- access to water supply and sanitation for all people.
als live without improved services (1). Improved In 2003, WHO also established the Household Water
access to water and sanitation may, but does not Treatment and Safe Storage Network, a consortium
necessarily, represent access to water or sanitation of nearly 100 organizations working throughout de-
services that meet international engineering and veloping nations. The aims of the network include
fostering collaboration, generat-
TA B L E 1 ing research, and exploring mea-
sures to scale up pilot projects. In
Categories of water-, sanitation-, and hygiene-related diseases another major initiative, WaterAid
has helped foster citizen-action
Category Description/disease groups to improve services as part
Waterborne Caused by the ingestion of water contaminated by human or an- of a global grassroots movement
imal excreta or urine containing pathogenic bacteria or viruses; in water and sanitation. In most
includes cholera, typhoid, amoebic and bacillary dysentery, and countries, the proportion of people
other diarrheal diseases. with access to improved water and
sanitation increased from 1990 to
Water-based Caused by parasites found in intermediate organisms living in
2002 (1). However, in the most im-
water; includes dracunculiasis, schistosomiasis, and some oth-
poverished regions, access remains
er helminths.
dismal and, unless significant im-
Water-related Caused by microorganisms with life cycles associated with in-
provements occur, numerous coun-
sects that live or breed in water; includes dengue fever, lym-
tries, including many of those in
phatic filariasis, malaria, onchocerciasis, and yellow fever.
sub-Saharan Africa, will not meet
Excreta-related Caused by direct or indirect contact with pathogens associated the UN MDGs for water and sani-
with excreta and/or vectors breeding in excreta; includes tra- tation by 2015 (3).
choma and most waterborne diseases. The adverse health impacts at-
Water collection and Caused by contamination that occurs during or after collection, tributable to lack of water and sani-
storage often because of poorly designed, open containers and improp- tation are significant. These effects
er hygiene and handling. are caused by exposure to patho-
Toxin-related Caused by toxic bacteria, such as cyanobacteria, which are genic microbes through various
linked to eutrophication of surface-water bodies; causes gas- routes, which are summarized in
trointestinal and hepatic illnesses. 6 categories in Table 1. The large
Adapted with permission from Refs. 17, 44, and 45. number of categories is an indica-
tion of the extent to which water-,

18 n Environmental Science & Technology / JANUARY 1, 2007


sanitation-, and hygiene-related diseases can affect in Table 1. Furthermore, compared with medical
populations. Many of the categories and diseases are treatment, water and sanitation services provide a
closely associated. As we discuss later, this associa- more cost-effective and locally sustainable solution
tion complicates environmental risk analysis. for alleviating the impacts of water-, sanitation-, and
Nearly 60% of infant mortality is linked to in- hygiene-related diseases (12).
fectious diseases, most of them water-, sanitation-, In the past decade, further evidence has emerged
and hygiene-related (4). Globally, diarrhea is the that supports the beneficial outcomes of water,
third largest cause of morbidity and the sixth larg- sanitation, and hygiene interventions in develop-
est cause of mortality (5). Disability-adjusted life ing countries. A meta-analysis of the impact of such
years (DALYs), a measure that combines the bur- interventions concluded that increasing water quan-
den from death and disability in a single index, al- tity reduced the occurrence of diarrheal diseases by
lows for the quantification of disease burden (6). The 25%, whereas point-of-use (POU) household water
global disease burden from water-, sanitation-, and treatment and improved sanitation led to reductions
hygiene-related diseases is significant, accounting in diarrheal diseases of 35% and 32%, respectively
for ~82,196,000 DALYs (7). In addition to the bur- (13). Sanitation and POU interventions may have
den from diarrhea, this estimate includes the impact resulted in greater reductions because they directly
from schistosomiasis, trachoma, and intestinal hel- block pathways of exposure. In contrast, increasing
minths. Table 2 illustrates
the global extent of morbid- TA B L E 2
ity and mortality figures for
diarrhea and other water-, Morbidity and mortality rates for selected water-, sanitation-, and
sanitation-, and hygiene-
related diseases. A study
hygiene-related diseases
conducted by the Pacific In- Estimated Estimated Cause/link
stitute estimated that if no morbidity mortality Unsanitary Unsafe Water
(episodes (deaths disposal of drinking Poor resources
action is taken to address Disease per year) per year) excreta water hygiene developmenta
the lack of water, sanitation, Diarrheal diseases 1 billion 2.2 million
and hygiene, as many as 135 Intestinal helminths 1.5 billion 100,000
million preventable deaths
Schistosomiasis 200 million 200,000
will occur by 2020 (8).
Trachoma 150 million b
The adverse effects of a
lack of water and sanitation a Water
 resources development refers to dams and farm irrigation schemes that have increased snail habitat, a vector for the schistosomia-
sis-causing parasites, and the likelihood of exposure with additional individuals working in irrigated fields where the snail breeds.
services extend beyond the b This
 reflects the number of active cases. Approximately 6 million cases of preventable blindness are due to trachoma.
unequivocal consequence of Adapted with permission from Ref. 8.

diseases. The collection of


water, primarily the responsibility of women and water quantity has the potential to indirectly im-
children, represents an additional burden. Up to prove hygiene practices, such as hand washing, by
6 hours each day may be spent in search of water providing households with a greater total amount
to meet household needs (9). Time spent in search of water that can be used for additional tasks. Inter-
of water forces children to miss school and women estingly, no improved benefit in disease reduction
to forgo potential opportunities to engage in small was seen in households where multiple interven-
business endeavors, such as growing and selling veg- tions were introduced (13). This may indicate that
etables or weaving mats. A lack of water may prevent health gains are not additive and/or that confound-
people from practicing proper hygiene habits, such ing factors become increasingly significant when the
as washing their hands before eating or after using effects of multiple interventions are measured. A re-
a latrine. Water scarcity may also limit the ability to cent review of 30 randomized and quasi-random-
grow and water vegetables, thus depriving individu- ized controlled studies supports earlier conclusions
als of essential nutrients needed to fight diseases. In that POU household treatment is more effective in
addition, the long-term consequences of diarrheal preventing diarrhea compared with treating water at
diseases have been linked to secondary health im- the source (14). The above studies and several others
pacts, such as malnutrition and reduced cognitive provide convincing evidence for the health benefits
function in children (10). that result from improved water and sanitation.

Foundation for improved health Environmental risk and pathogen pathways


Substantial evidence indicates that water, sanitation, Taking action to improve health requires under-
and hygiene interventions improve health. A multi- standing the factors that influence exposure and
faceted review of the health effects from improved health outcomes. The Multiple ExposureMultiple
water supply and sanitation found significant reduc- Effect (MEME) model provides a way to systemati-
tions in both the severity and prevalence of diarrhea cally understand the interrelated nature of these
and infectious diseases (11). Specifically, dracuncu- factors (15). Exposure may be the result of proxi-
liasis, schistosomiasis, and trachoma were reduced mal causes, such as drinking water that becomes
by 77%, 78%, and 27%, respectively. Improved water contaminated with excreta-related pathogens in the
and sanitation serve as important barriers to the home, or distal causes, such as climate. Although
various routes of pathogen exposure summarized the pathways of exposure have been described, the

JANUARY 1, 2007 / Environmental Science & Technology n 19


FIGURE 2

Exposures and health outcomes are complicated by interrelated factors


Adapted with permission from Ref. 15.

Contexts

Social conditions

Economic conditions

Demographic conditions

Exposure Health outcome

Distal
Less
Ambient severe
environment Causes Well-being

Morbidity
Community
Attributable Mortality
Home to More
severe
Proximal

Preventive Remedial
actions actions

Actions

relative influence of various factors, especially those trachoma. The disease is transmitted when drop-
resulting from social, economic, and demographic lets containing C. trachomatis are spread through
conditions, on both exposure and health are less touching infected eyes, contact with contaminated
well understood. The linkages between these fac- pillows and clothes, and eye-seeking fliesMusca
tors within the framework of the MEME model are sorbensthat serve as mechanical vectors (16).
illustrated in Figure 2. When animal and human hosts coexist, both can
The MEME model serves as a basis for examin- serve as reservoirs for pathogen survival and repro-
ing the ability of water, sanitation, and hygiene in- duction, compounding the challenge of describing
terventions to reduce exposure and improve health risk of exposure. Examples include nontyphi Salmo-
outcomes. For interventions to be effective in reduc- nella, E. coli, and the bovine species of Cryptospo-
ing risk and blocking pathogen pathways, they must ridium (17). As we describe in the following section,
consider the environmental, cultural, and economic reducing the potential sources of pathogens through
conditions of a particular community. An example POU household treatment and improved sanitation
of such an intervention is community-led sanita- can significantly reduce the risk of exposure (18).
tion, which began in Bangladesh and has spread
throughout South and Southeast Asia. It focuses A shift to household technologies
on sustainability by supporting communities in Lending institutions and national governments have
prioritizing needs and developing sanitation inter- traditionally focused on implementation of large,
ventions that incorporate local materials and mar- centralized treatment systems. Such systems do not
keting strategies to encourage latrine construction. serve rural areas, where populations are dispersed
The result has been an explosion of new, innovative, and the proportion served is less than half that in
community-developed and -managed technologies, urban areas (1). Rapidly growing, unplanned, peri-
significant health gains, and overall improvements urban areas are also not effectively served by cen-
in well-being (3). tralized systems (19). Centralized approaches are
Risk assessment increases in complexity when often plagued by high capital costs, lack of proper
pathogens have several routes of transmission and/ operation, and an overreliance on treatment tech-
or vertebrate hosts. An example of a pathogen with nologies that cannot be afforded or maintained.
multiple routes is Chlamydia trachomatis, the bac- Given the shortfalls of centralized systems, it is ap-
terium that causes the potentially blinding disease parent that a variety of options are needed, espe-

20 n Environmental Science & Technology / JANUARY 1, 2007


cially in developing countries, where conditions are Conclusive results about which POU technologies
challenging. A decentralized approach that relies on are the most effective in improving health are still
household water treatment and sanitation technolo- lacking. Because of heterogeneities between com-
gies may present a viable alternative (1922). munities and in the methodology of epidemiological
POU treatment. POU treatment offers a local- studies, comparing outcomes is difficult. The per-
ly modified and managed solution in areas where formance of POU treatments is highly dependent on
centralized systems are ineffective. The critical source water quality and the degree to which house-
advantage of POU treatment is that it provides a holds adhere to the operation and maintenance re-
barrier to pathogen exposure immediately before quirements. A review of the promotion of chlorine
consumption. Even when source water is deemed disinfection in Malawi found that incorrect dos-
safe, poor hygiene during collection, storage, and age (8100% of the appropriate concentration was
handling of water results in contamination (23). For used) resulted in a chlorine residual that was far
example, reduction in diarrheal diseases is doubled less than suggested (29). An additional challenge is
when water is treated immediately before use (13). determining whether health outcomes are primar-
Therefore, for maintaining the quality of treated wa- ily due to POU treatment or confounding factors,
ter within the home, safe storage is an important such as hand washing, education, economic well-
complement to POU. An extensive review of POU being, and culture. For example, a drinking-water
technologies concluded that simple, acceptable, and hand-washing study in squatter settlements in
low-cost interventions at the household and com- Karachi, Pakistan, found no significant difference in
munity level are capable of dramatically improving reduction of daily longitudinal prevalence of diar-
the microbial quality of household stored water and rhea among households that used POU technologies
reducing the attendant risks of diarrheal disease and alone (64%), hand washing alone (51%), and a com-
death (24). bination of POU treatments and hand washing with
In laboratory studies, POU technologies have soap (55%) (30). Therefore, additional comparative
demonstrated removal and/or inactivation of patho- and longitudinal health studies are required to de-
gens at varying rates. PUR, a flocculant/disinfec- termine which technologies are most effective.
tant that is sold in individual packets, is the most Understanding the primary motivators that drive
effective, providing >7 log removal of bacteria and households to use POU technologies is important
>4 log removal of viruses (21). Chlorine bleach typ- for sustaining use and achieving long-term health
ically achieves only 2 log removal for both bacte- gains. Some of the main factors are affordability,
ria and viruses (25). Chlorine is particularly poor aesthetic and taste preferences, and the ability to
for treating turbid water (>1 nephelometric turbid- manufacture POU technologies locally. The cost of
ity unit) or chlorine-resistant pathogens, including POU treatments is a serious hurdle to adoption, es-
many types of protozoan cysts. However, the chlo- pecially in developing countries such as Tanzania,
rine residual protects against recontamination; this where for decades a free water for all policy ex-
is especially important in homes where hygiene is isted (31). Placing a price on POU units is important
substandard. to recover production costs and increase sense of
Health gains from POU techniques will only be ownership. However, water is viewed as a funda-
realized if treatment is effective in the communities mental human right, and denying access because of
where such technologies are used. This is a greater inability to pay creates a serious ethical dilemma (19,
challenge than achieving high removal rates of patho- 32). POU technologies that can be generated local-
gens in the controlled laboratory environment. Re- lysuch as chlorine which has been manufactured,
cent studies in Kenya, Guatemala, and India have packaged, and distributed by local microenterpris-
demonstrated that use of POU treatments leads to a es under brands such as WaterGuard in Tanzania
reduction in diarrhea by 40% for PUR and solar dis- and Safe Water (SrEau) in Madagascarare more
infection and by up to 85% for chlorine (20, 26, 27). likely to be sustained after initial funding ceases. In
These results suggest that although chlorine is less contrast, PUR currently cannot be manufactured lo-
effective in removing bacteria and viruses, it may lead cally, thus preventing its widespread adoption and
to a greater reduction in diarrhea because of econom- distribution. Long-term, sustained use of POU tech-
ic and cultural advantages relating to low cost, ease of nologies may be reinforced as individuals experi-
use, and its ability to be manufactured locally. Other ence the benefits of improved water and sanitation.
studies, however, have not found such a large advan- Furthermore, reductions in water-, sanitation-, and
tage for chlorine. A study in Guatemala that evaluated hygiene-related diseases allow individuals to engage
sodium hypochlorite (bleach) and PUR demonstrated in more productive work and attend school, both of
no significant difference between the two technolo- which may lead to economic development, improved
gies, both of which reduced diarrhea by ~25% (28). standards of living, and more hygienic conditions.
Precise rankings of POU-based disease reduction Household sanitation. A simple pit latrine, one
are difficult to ascertain, as we describe in the fol- of the most basic forms of household sanitation, of-
lowing paragraph, but more qualitative conclusions fers an inexpensive alternative to expensive and en-
are possible. The review on household technologies vironmentally intensive sewage systems. Although
concluded that solar disinfection with clear plastic sanitation is important for the safe disposal of ex-
bottles and chlorination plus storage in an improved cretathe source of pathogens that cause the ma-
vessel led to significant reductions in diarrhea and jority of water-, sanitation-, and hygiene-related
other infectious diseases (24). diseasesit has not received the same attention as

JANUARY 1, 2007 / Environmental Science & Technology n 21


water treatment (33). One of the major challenges efforts to improve water and sanitation. The lack of
with sanitation is developing and implementing in- water quality standards and the difficulty in enforc-
novative, user-friendly, low-cost systems (34). ing standards also limit the ability to improve health
Current efforts focus on overcoming some of the outcomes. Even countries where such standards ex-
limitations of the simple pit latrine and expanding ist frequently lack the personnel, monitoring equip-
sanitation coverage. Some evidence has linked the ment, and political will to ensure that quality and
standard latrine to contamination of groundwater health guidelines are enforced (38).
by bacteria and nutrients (35). In addition, tradition- Decentralization has not solved perhaps the
al latrines may harbor offensive odors and flies. The largest problem facing water and sanitation proj-
ventilated improved pit latrine improves on the stan- ectssustaining long-term use and operation. For
dard design by allowing odors to escape, prevent- example, at the conclusion of the 5-year, $135 mil-
ing flies from entering, and in many cases sealing lion Indonesian Rural Water Supply and Sanitation
the pit to prevent groundwater contamination (33). Sector Project, fewer than half of the ~3 million in-
Ecological sanitation, although practiced in China tended beneficiaries had received any services (39).
for centuries, has only recently been gaining accep- In addition, only 3040% of the water and sanitation
tance throughout the world as an effective means to facilities constructed were still functioning or in use
recycle the nutrients in excreta for use in agriculture. 4 years after the project was completed (39). This
This improves crop production and, ultimately, the demonstrates both an initial lack of capacity and/or
nutritional health of the population (36). political will to implement services and a lack of local
A typical latrine design consists of a superstruc- incentive to operate and maintain facilities. Efforts
ture that sits above a raised, sealed vault. The toi- in rural Africa had similar outcomes. Throughout
let, either of the sitting or standing variety, usually the continent, of the ~250,000 hand pumps currently
diverts urine and excreta into two separate cham- installed, <50% are estimated to be operational (40).
bers within the vault. Urine, which is nearly patho- Six months after implementation of a chlorine-dis-
gen-free and contains high amounts of nitrogen and infection and safe-storage project in rural Kenya, on
phosphorus, can be diluted with water and used im- average only 33% of households had chlorine resid-
mediately for crop fertilization. Excreta must remain ual (evidence of use of POU treatments) and <20%
in the vault for a period of several months to allow had purchased storage pots (41). Project participa-
for pathogen removal through die-off, desiccation, tion in individual villages was variable, ranging from
and predation by microorganisms (36). Once patho- 0 to 76%. This suggests that further understanding
gen removal is nearly complete and excreta can be of the factors that lead to adoption, even within re-
safely handled, it can be applied to crops. Advan- gional areas, is critical for sustaining interventions
tages of ecological sanitation include the ability to and achieving health gains.
empty and reuse storage vaults, production of an Increasing funding alone is not the solution. Ir-
organic and free source of fertilizer, and prevention respective of the type of system, an emphasis should
of groundwater pollution that can occur when pits be placed on implementing demand-based rather
are unsealed and located near the aquifer. than supply-based systems, where communities
The promotion and large-scale implementation commit to partnering in the development of lo-
of latrines are at least as important as, if not more cally based systems. Once local partnerships and
important than, improvements in sanitation design. management structures have been established, gov-
Latrine marketing does not focus on extolling the ernmental agencies and nongovernmental organi-
virtues of improved health but rather on other ben- zations should assist in establishing an effective
efits such as reduced smell, cleaner surroundings, monitoring program in conjunction with a financial
privacy, and less embarrassment when visitors need system that uses both local and government funds to
to use facilities (37). Combining low-cost technology pay for ongoing maintenance and improvements.
with marketing efforts to secure community par-
ticipation and management has been a successful Overcoming the challenges
way of expanding sanitation coverage. One nota- Overcoming the obstacles to providing water and
ble example is in India, where 1 million pit latrines, sanitation for all will require policies and invest-
which can be modified to suit different incomes and ments that address the interrelated nature of water,
preferences, have been built since 1970 under the sanitation, and health. Policies and funding initia-
auspices of the nongovernmental organization Su- tives that focus on either water and sanitation or
labh International Social Service Organization (3). disease treatment ought to be replaced by integrat-
Further efforts are required in the marketing and ed endeavors with a focus on disease prevention.
implementation of household latrines before similar Such a strategy will serve to enhance the already
success can be realized throughout the globe. proven cost-effectiveness of improvements in water
and sanitation and make use of overlapping areas
Obstacles to achieving water and sanitation of knowledge and responsibility. Such integrated
forall approaches are especially important in developing
In many developing countries, a lack of financial countries, where funding and resources are scarce
resources and a low prioritization of water and sani- and competing needs are immense.
tation constrain both the maintenance and expan- Three main areas require further investigation
sion of services. In addition, lack of accountability, to provide the information and necessary tools
corruption, and inefficient management all plague to tackle current challenges. First, current knowl-

22 n Environmental Science & Technology / JANUARY 1, 2007


edge about water, sanitation, and health should be and sustained. The results of such efforts will un-
translated into action through community projects doubtedly increase the rate at which we approach
and research. Community-based research includes the UN MDGs and serve the billions who currently
gaining a better understanding of the key factors live without basic water or sanitation.
driving long-term use of interventions, establishing
hygiene behavior-change initiatives within existing Maggie A. Montgomery is a doctoral student in the envi-
community structures, and creating consumer de- ronmental engineering program at Yale University. Me-
mand for interventions through marketing efforts. nachem Elimelech is the Roberto Goizueta Professor of
Evidence from community research should be used Chemical and Environmental Engineering at Yale Uni-
to modify and improve existing policies and invest- versity and the director of the environmental engineer-
ments. Second, improved methodology and indica- ing program. Address correspondence about this article
tors should be developed for quantifying the health to Elimelech at menachem.elimelech@yale.edu.
impacts of interventions for water, sanitation, and
hygiene. These indicators should be easy for local References
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24 n Environmental Science & Technology / JANUARY 1, 2007

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