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Name: B cell Type of response: Specific

Comes from: Bone marrow


Role in immune response: Engulfs antigens to become an antigen-representing
cell. Once activated by cytokines released by the T helper cell, it divides to
produce clones that differentiate into B memory and plasma cells.

Name: B memory cell Type of response: Specific


Comes from: B cell
Role in immune response: Rapidly divides upon a second encounter of the
same antigens.

Name: B effector cell Type of response: Specific


Comes from: B cell
Role in immune response: Differentiates into plasma cell, which produce only
one type of antibody.

Name: Plasma cell Type of response: Specific


Comes from: Activated B effector cell
Role in immune response: Produces antibodies specific to a particular antigen.

Name: T helper cell Type of response: Specific


Comes from: produced in the bone marrow, mature in the thymus
Role in immune response: binds to APC with complementary receptors,
activating them to divide and once activated, they produce cytokines which
stimulate other cells involved in the specific immune response.

Name: Memory T helper cell Type of response: Specific


Comes from: activated T helper cell
Role in immune response: activated upon second encounter to same antigen,
allowing rapid response.

Name: Active T killer cell Type of response: Specific


Comes from: produced in the bone marrow, mature in the thymus
Role in immune response: bind to infected cells (APCs) and releases a chemical
(perforin) that cause pores to form in the cell membrane, resulting in lysis and
the infected cell dies.

Name: Macrophage Type of response: Both


Comes from: monocytes which come from bone marrow and circulate in the
blood, once they leave the blood, they mature
Role in immune response: engulf and digest bacteria and cells presenting non-
self antigens and debris from damaged cells. They can also act as APCs and
(thus) activate T helper cells.

Name: Neutrophil Type of response: Non-specific


Comes from: bone marrow
Role in immune response: able to leave capillaries by squeezing between the
cells of the capillary walls and they remove bacteria from the body be
engulfing and destroying them.

Name: Natural killer cell Type of response: Non-specific


Comes from: bone marrow
Role in immune response: type of non-specific lymphocyte act against viruses
and other intracellular microbes by inducing apoptosis of infected cells.
Activated by cytokines and interferon.

Name: Antigen-presenting cell Type of response: Both


Comes from: infected cells or macrophages
Role in immune response: displays foreign antigens acting as a signal,
triggering a response.