Weekly Research Report

Name: Kai Sunahara

Date: 1/17/17
Directions: After reading and annotating, complete the following table and collect it with other weekly reports
to help you develop your findings and prepare for the assessments.
Assignment (what type of source was assigned):

Title:What you need to know about CRISPR

Author/Speaker: Ellen Jorgensen
Pages read (if applicable):
MLA Citation:
Jorgensen, Ellen. What you need to know about CRISPR. Youtube, Uploaded by Ted, 24
October 2014, www.youtube.com/watch?v=1BXYSGepx7Q

Guiding Question(s): How CRISPR lets us edit DNA. How cheap and easy is CRISPR

Summary statements of the author/speakers main ideas

The broke Cas9 and RNA finds DNA it wants to edit, breaks the double helix, and inserts the edit
Since it has to be inserted through a virus the effects are still unknown, long term
CRISPR is relatively cheap but has to be done in a lab
CRISPR is not easy to do yet but, if future technology can solve long term effects of Virus then it will

Embedded quotation (page #) How does it answer/relate to the Guiding Question?

The guide RNA and the Cas9 It tells us how is it that CRISPR is able to edit the DNA.
protein complex together bounce
along the genome, when they find a
spot where the guide RNA matches
it inserts itself into the double helix
strands. 2:55 Ellen Jorgensen

You still need a professional lab to Since you still have to do all of this work inside a
work in 5:34 Ellen Jorgensen professional lab, the work will still costs a bit.
If you're trying to do it on a whole If you spend time figuring out the effects of it, CRISPR
organism it gets tricky. will eventually become easier.
You are probably going to have to
use a virus to insert specific DNA

Unfamiliar words Definitions

RNA ribonucleic acid, a nucleic acid present in all living cells.

Its principal role is to act as a messenger carrying
instructions from DNA for controlling the synthesis of
proteins, although in some viruses RNA rather than DNA
carries the genetic information

Cas-9 Cas9 is an RNA-guided DNA endonuclease associated

with the CRISPR type II adaptive immunity system in
Streptococcus pyogenes, among other bacteria

DNA Deoxyribonucleic acid is a molecule that carries the

genetic instructions used in the growth, development,
functioning and reproduction of all known living
organisms and many viruses.

CRISPR Clustered regularly interspaced short palindromic

repeats