DAFTAR ISI

HALAMAN JUDUL............................................................................................. i
LEMBAR PERSETUJUAN................................................................................. ii
ABSTRAK............................................................................................................. iv
ABSTRACT........................................................................................................... v
BIODATA DIRI..................................................................................................... vi
MOTTO................................................................................................................. vii
PERSEMBAHAN................................................................................................. viii
KATA PENGANTAR............................................................................................ ix
DAFTAR ISI.......................................................................................................... x
DAFTAR GAMBAR............................................................................................. xiii
DAFTAR TABEL.................................................................................................. xiv

BAB 1 PENDAHULUAN..................................................................................... 1
1.1 Latar Belakang......................................................................................... 1
1.2 Rumusan Masalah.................................................................................... 3
1.3 Tujuan Penelitian..................................................................................... 3
1.3.1 Tujuan Umum................................................................................. 3
1.3.2 Tujuan Khusus................................................................................ 3
1.4 Manfaat Penelitian................................................................................... 3
1.4.1 Manfaat Ilmiah................................................................................ 3
1.4.2 Manfaat Aplikatif............................................................................ 3
1.5 Ruang Lingkup Penelitian........................................................................ 4

BAB 2 TINJAUAN PUSTAKA............................................................................ 5

2.1 Belimbing Manis (Averrhoa carambola)................................................. 5
2.1.1 Klasifikasi....................................................................................... 5
2.1.2 Sinonim........................................................................................... 5
2.1.3 Nama umum.................................................................................... 5
2.1.4 Morfologi tanaman.......................................................................... 6
2.1.5 Kegunaan........................................................................................ 7
2.1.6 Kandungan kimia............................................................................ 7
2.2 Jus............................................................................................................ 9
2.2.1 Definisi Jus...................................................................................... 9
2.2.2 Manfaat Jus Belimbing................................................................... 9

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 2.3 Peranan Kandungan Gizi Belimbing Manis Terhadap
Peningkatan Kadar Trombosit.................................................................. 10
2.3.1 Vitamin C........................................................................................ 10
2.4 Trombosit................................................................................................. 13
2.4.1 Fisiologi Trombosit......................................................................... 13
2.4.2 Fungsi Trombosit............................................................................ 14
2.4.3 Mekanisme Kerja Trombosit........................................................... 15
2.4.4 Trombositosis, Trombositopenia, dan Gangguan Perdarahan......... 15
2.5 Tikus Putih............................................................................................... 18
2.6.1 Taksonomi Tikus Putih (Rattus novercigus)................................... 18
2.5.2 Karakteristik Tikus Putih (Rattus novergicus)................................ 18
2.6 Kerangka Teori......................................................................................... 19
2.7 Kerangka Penelitian................................................................................. 20
2.8 Hipotesis.................................................................................................. 20

BAB 3 METODE PENELITIAN......................................................................... 21

3.1 Jenis Penelitian......................................................................................... 21
3.2 Tempat dan Waktu penelitian................................................................... 22
3.2.1 Tempat Penelitian............................................................................ 22
3.2.2 Waktu Penelitian............................................................................. 22
3.3 Subjek dan Sampel Penelitian.................................................................. 22
3.3.1 Subjek Penelitian............................................................................ 22
3.3.2 Kriteria Sampel Penelitian.............................................................. 22
3.3.3 Besar Sampel.................................................................................. 23
3.3.4 Teknik Sampling............................................................................. 23
3.4 Rancangan Penelitian............................................................................... 24
3.5 Alat dan Bahan Penelitian........................................................................ 24
3.5.1 Alat Penelitian................................................................................. 24
3.5.2 Bahan Penelitian............................................................................. 26
3.6 Dosis Penelitian....................................................................................... 26
3.7 Klasifikasi Variabel.................................................................................. 27
3.7.1 Variabel Bebas................................................................................ 27
3.7.1 Variabel Terikat............................................................................... 27
3.7.3 Variabel Terkendali......................................................................... 27
3.7.4 Variabel Tidak dapat Dikendalikan................................................. 28
3.8 Definisi Operasional Variabel.................................................................. 29
3.8.1 Jus Buah Belimbing (Averrhoa carambola)................................... 30
3.8.2 Kadar trombosit Darah.................................................................... 30
3.9 Prosedur Penelitian.................................................................................. 31
3.9.1 Persiapan dan Pembuatan Uji......................................................... 31
3.9.2 Perlakuan......................................................................................... 31
3.9.3 Penghitungan Kadar Trombosit...................................................... 32
3.9.4 Setelah Perlakuan............................................................................ 33
3.10 Analisa Data........................................................................................... 33

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BAB 4 HASIL DAN PEMBAHASAN................................................................. 34
4.1 Hasil Penelitian....................................................................................... 34
4.2 Analisis Data.......................................................................................... 36
4.2.1 Uji Prasyarat Uji Parametrik......................................................... 37
4.2.2 Uji One-way Anova....................................................................... 38

BAB 5 KESIMPULAN DAN SARAN................................................................. 39

5.1 Kesimpulan............................................................................................. 39
5.2 Saran....................................................................................................... 40

DAFTAR PUSTAKA
LAMPIRAN

DAFTAR GAMBAR

Gambar 2.1 Belimbing Manis (Averrhoa carambola)............................................ 6

Gambar 2.2 Gambaran Trombosit Pada Apusan Darah Tepi.................................. 13
Gambar 2.3 Proses Penyumbatan Luka Oleh Trombosit........................................ 14
Gambar 2.4 Tikus Putih Jantan (Rattus novergicus)............................................... 18
Gambar 2.5 Kerangka Pemikiran............................................................................ 19
Gambar 2.6 Kerangka Konsep................................................................................ 20

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Gambar 3.1 Bagan Rancangan Penelitian............................................................... 24
Gambar 4.1 Histogram rerata kadar trombosit darah tikus putih sebelum dan
setelah perlakuan (mg/dl).................................................................. 35

DAFTAR TABEL

Tabel 2.1 Kandungan gizi dalam 100 gram buah belimbing manis........................ 8
Tabel 2.2 Angka kecukupan vitamin C yang dianjurkan........................................ 12
Tabel 2.3 Nilai vitamin C pada berbagai buah (mg/100gram)................................ 12
Tabel 2.4 Gangguan perdaraham............................................................................ 17
Tabel 2.5 Manifestasi klinis umum gangguan perdarahan...................................... 17

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Tabel 3.1 Rancangan penelitian.............................................................................. 21
Tabel 3.2 Definis Operasional................................................................................. 30
Tabel 4.1 Hasil pemeriksaan kadar trombosit darah tikus putih pretest dan posttest
pada setiap kelompok perlakuan (mg/dl)............................................... 34
Tabel 4.2 Rerata kadar trombosit darah tikus putih sebelum dan setelah
perlakuan (mg/dl)................................................................................... 35
Tabel 4.3 Hasil uji One-way Anova dengan distribusi rata-rata kadar trombosit
setelah perlakuan (mg/dl)....................................................................... 38

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