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  • Pathophysiology of Gastrointestinal Bleeding Secondary To Bleeding Polyps

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    GinoTeves
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    Polyps in the gastrointestinal tract can bleed, leading to hematochezia or anemia. Risk factors for developing polyps include increasing age, family history of colon polyps, tobacco and alcohol use, obesity, lack of exercise, type 2 diabetes, increased meat and fat intake, and African American race. When polyps form and grow in the mucosa, cell renewal is slower, leading to a hypermature epithelium that is prone to bleeding, especially for large polyps. This can cause hematochezia, anemia, hypotension, tachycardia and other signs of hypovolemia.

    Originalbeschreibung:

    Pathophysio

    Originaltitel

    PATHOPHYSIO-HEMATOCHEZIA

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    Polyps in the gastrointestinal tract can bleed, leading to hematochezia or anemia. Risk factors for developing polyps include increasing age, family history of colon polyps, tobacco and alcohol use, obesity, lack of exercise, type 2 diabetes, increased meat and fat intake, and African American race. When polyps form and grow in the mucosa, cell renewal is slower, leading to a hypermature epithelium that is prone to bleeding, especially for large polyps. This can cause hematochezia, anemia, hypotension, tachycardia and other signs of hypovolemia.

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    214 Ansichten1 Seite

    Pathophysiology of Gastrointestinal Bleeding Secondary To Bleeding Polyps

    Hochgeladen von

    GinoTeves
    Polyps in the gastrointestinal tract can bleed, leading to hematochezia or anemia. Risk factors for developing polyps include increasing age, family history of colon polyps, tobacco and alcohol use, obesity, lack of exercise, type 2 diabetes, increased meat and fat intake, and African American race. When polyps form and grow in the mucosa, cell renewal is slower, leading to a hypermature epithelium that is prone to bleeding, especially for large polyps. This can cause hematochezia, anemia, hypotension, tachycardia and other signs of hypovolemia.

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    von 1

    PATHOPHYSIOLOGY OF GASTROINTESTINAL BLEEDING SECONDARY TO BLEEDING

    POLYPS

    Risk Factors:
    Age Inflammatory intestinal conditions
    Family history of colonic polyps Tobacco and alcohol use
    Obesity and lack of exercise Race (African-Americans > risk)
    Type 2 diabetes Increased meat and fat intake

    In the mucosa, cell renewal is the


    same as of normal mucosa but with
    longer turnover time and delayed
    migration

    Hypermature epithelium

    Polyp formation and growth

    Large polyps tend to bleed

    Hematochezia
    Lab Result: Stool exam
    Grossly bloody; TNTC/hpf; 0-1 WBC/ hpf; Neg ova, parasites, amoeba

    Increased RBC destruction Hypovolemia


    Abdominal pain
    (increased BUN, and creatinine)
    HPI: intermittent
    colicky, left sided lower
    abdominal pain Anemia Hypotension Cardiac
    Lab Results: Hgb = 8g% P.E.: 80/60 mmHg compensation
    Hct= 24 %

    Tachycardia
    P.E.: 120 bpm
    HPI: Gradual pallor
    Dizziness
    Lightheadedness
    P.E.: pale palpebral
    conjunctivae, lips,
    nailbeds, palms, and
    soles

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