Beruflich Dokumente
Kultur Dokumente
Obese Persons
Comparison of Intra-arterial and Auscultatory Measurements*
KURT BERLINER, M.D., HERLEY FUJIY, M.D., DUK Ho LEE, M.D., MUHTAR YILDIZ, M.D.
and BERNARD GARNIER, M.D.
* From the Department of Medicine, New York Medical College, Metropolitan Medical Center, New York, New
York.
TABLE I
Summary of All Blood Pressure Determinations : Indirect and Direct Intra-Arterial
- - -
I Direct Intra-arterial
Higher
Indirect Method
1Ponderal Reading
Ci3.W Weight Method
NO. Age (lb.)
Height Index
(W/H)
(Cuff) I- Highest Lowest
Reading Reading
TABLE I (Continued)
-
Blood Pressures (mm. Hg)
Direct Intra-arterial
Higher
Indirect Method
Ponderal Reading
Case We@ Method
Age Height Index
No. (lb.) (Cuff) Highest Lowest
(W/H)
Reading Reading
51 49 183 491/1# 2.950 210 114 212 108 209 107 Direct cuff
52 60 198 57 2.955 192 132 200 125 192 120 Direct CUff
53 54 190 5 4 2.968 103 72 120 58 112 55 Direct cuff
54 46 196 5 6 2.969 150 75 159 83 151 82 Direct Direct
55 57 200 57 2.985 166 110 168 112 159 106 Direct Direct
56 69 200 57 2.985 176 94 170 98 166 69 cuff Direct
57 50 212 510 3.028 140 78 143 72 132 70 Direct cuff
58 63 200 56 3.030 126 62 121 54 116 55 cuff cuff
59 51 176 410 3.034 182 90 195 100 185 95 Direct Direct
60 65 213 510 3.042 142 60 124 56 120 56 Cuff cuff
61 48 200 54 3.125 160 90 170 85 142 88 Direct Cuff
62 66 217 59 3.144 147 40 152 43 150 45 Direct Direct
63 69 1921/ 51 3.155 185 95 185 95 180 85 Same Same
64 65 193 51 3.163 206 130 195 113 181 110 Cuff Cuff
65 49 197 5 2 3.177 202 103 206 97 201 97 Direct cuff
66 68 183 4 9/* 3.182 128 90 150 68 135 64 Direct cuff
67 56 202 5 2 3.258 193 94 174 68 165 75 Cuff cuff
68 51 207 5 21/2X 3.312 186 108 200 122 190 120 Direct Direct
69 44 220 55 3.384 200 140 180 140 170 136 Cuff Same
70 36 220 55W 3.384 148 111 154 97 143 95 Direct cuff
71 60 210 5 2# 3.387 141 50 159 65 138 57 Direct Direct
72 60 225 5 l/s 3.488 222 126 223 110 214 111 Direct Cuff
73 59 232 56 3.515 122 88 126 80 120 80 Direct Cuff
74 55 239 57 3.567 192 115 198 110 195 110 Direct cuff
75 53 226 53 3.587 210 110 220 115 210 105 Direct Direct
76 59 216 50 3.600 154 90 180 88 168 83 Direct cuff
77 57 224 52 3.612 158 104 176 120 164 119 Direct Direct
78 73 212 410/1 3.623 146 92 156 101 136 91 Direct Direct
79 62 227 52 3.632 168 99 173 120 152 109 Direct Direct
80 50 221 411 3.745 254 142 242 123 229 117 cuff cuff
81 45 244 5 5 3.760 164 80 173 82 162 78 Direct Direct
82 34 248 5 5/2 3.786 133 77 137 73 122 73 Direct cuff
83 57 231 51 3.786 120 64 131 82 120 75 Direct Direct
84 58 238 50 3.966 188 108 180 96 170 95 Cuff Cuff
85 27 265 55 4.076 126 84 118 78 116 81 cuff Cuff
86 65 265 55 4.076 125 76 129 78 119 74 Direct Direct
87 51 264 53 4.190 160 90 176 83 166 83 Direct cuff
88 36 290 59R 4.202 184 123 201 122 185 111 Direct Cuff
89 71 237 48 4.232 188 80 205 87 190 82 Direct Direct
90 65 255 50 4.250 238 130 230 118 218 124 Cuff cuff
91 59 274 5 4 4.281 170 92 152 95 138 88 cuff Direct
92 38 270 5 3 4.285 156 102 159 94 154 97 Direct cuff
93 62 275 51 4.524 190 90 171 83 137 86 cuff cuff
94 63 275 51 4.524 196 94 152 66 134 61 cuff cuff
95 48 287 5 3 4.555 262 138 212 110 200 95 cuff cuff
96 38 278 4 11/2 4.672 178 100 150 85 139 84 cuff cuff
97 48 276 411 4.677 236 150 208 123 205 125 cuff cuff
98 58 315 5 ,I/%. 5.121 141 88 135 67 120 66 cuff cuff
99 49 350 57 5.223 250 150 199 115 178 104 cuff cuff
100 58 391 591/2ff 5 625 159 116 162 91 140 87 Direct cuff
I
THE AMERICAN JOURNAL OF CARDIOLOGY
Blood Pressure in Obese Persons 13
Discrepancy
Reading
Actual
pared
readings
Differences
com-
of 1 or 2
23 ~ 14 2 39
Readings
identical
El. Thirty-Nine
L
Nmobere Persons
I 1
mm. disregarded 19 13 7 39
28, 28, 28, 44, 50 and 51 mm., respectively. Diastolic Blood Pressure Readings-Comparison of
Direct and Indirect Measurements
In the nonobese persons, too, most of the dis-
crepancies were minor. However, gross over-
Comparison
estimation of systolic pressure also occasionally
occurred among these lean persons, in one in- Reading
Direct Indirect / Readigs
i 2:
stance amounting to 37 mm. Underestima- Reading Reading
tion of systolic pressure of lean persons by the Higher Higher i Identical
___=
indirect method was more common and more
A. Sixty-One Obese Pmons
marked, amounting to as much as 25 to 40 mm.
Diastotic Pwssure: In both groups systolic / I I
Actual readings com-
pressure was underestimated by the indirect pared 19 39 3 61
method more often that it was overestimated. Differences of 1 or 2
mm. disregarded 16 36 9 ! 61
The opposite was found when diastolic pressures
were compared. The indirect method over-
B. Thirty-Nine Nonobcre Persons
estimated diastolic pressure in the majority of
/ / ,
all cases, obese and nonobese. Tables IV and Actual readings corn
v summarize the comparisons of diastolic pres- pared 9 26 4 39
Differences of 1 or Z
sure in the obese and nonobese subjects, Table mm. disregarded 23 9 39
IV showing the frequency of the discrepancies,
Table v their magnitude. Among the obese
subjects, most of the discrepancies in diastolic pressure did not occur; gross overestimation
pressure were again minor. Gross underestima- occurred four times, amounting to 16 to 22 mm.
tion occurred only twice (by 16 and 18 mm.) Extreme Obesity us. Leanness: The similarity of
and gross overestimation much more frequently, findings in both groups at first seemed to indi-
twelve times (by 16 to 35 mm.) In the non- cate that obesity has little effect on the meas-
obese group gross underestimation of diastolic urement of blood pressure. Very different re-
JULY 1961
Berliner et al.
8
- estimation of systolic blood pressure by the
indirect method (Table VII). The discrepan-
T
Direct
TABLE VI
Ten Stoutest and Ten Leanest Subjects-Comparison of Direct and Indirect Blood Pressure Measurements
Systolic 2 cases (each 8 cases (by 6, 18, 19, 4 cases (by 1, 1,l and 6 cases (by 3, 3, 3, 3, 4 0
oressure bv3mm.) 28,28,44,50 and 51 6 mm., respectively) and 8 mm., respec-
mm., respectively) tively)
9 cases (by 4,5,15,15, 2 cases (by 2 and 6 7 cases (by 4, 5, G, 6, 13, 1
21, 25, 28, 28 and mm., respectively) 15 and 19 mm., re-
35 mm.. resoec- spectively)
1 tively) A
JULY 961
16 Berliner et al.
consistency had very little effect upon the esti- infrequently the sleeve is too short and part of
mated blood pressure, whereas cotton, wool and the cuff balloons out when it is inflated. After
sponge rubber increased the estimated blood readjusting the sleeve, markedly different
pressure. Apparently some materials when readings were obtained. Attempts to lengthen
interposed between the sphygmotnanometer the sleeve by adding a bandage caused even
cuff and the artery spread the pressure over a greater errors.
wider area so that, in fact, the pressure upon the We always bear in mind the possibility of
outside of the artery is less than the pressure falsely high readings when dealing with ex-
within the cuff. Hence the blood pressure is tremely stout persons and are, therefore, not
overestimated. The estimated pressure can be likely to make an unwarranted diagnosis of hy-
brought back to a pressure nearer to that ob- pertension. Moreover, most of these very obese
tained under standard conditions if the cuff is persons are true hypertensive subjects anyhow,
widened. This explanation of the falsely high as shown by intra-arterial measurement; there
readings is plausible and should be accepted is little danger of falsely classifying them as
without qualification. Pickering, Roberts and hypertensive subjects. In the rare cases in which
SowryzO reviewed the comparisons reported by there is doubt, intra-arterial measurement
Ragan and Bordley5 and published a list of should be taken.
adjustments for arm circumference to be made The large size of the arm, on the other hand,
to auscultatory pressure. The subtractions to does not always cause falsely high readings.
be made from systolic pressure readings in This was nicely shown by the stoutest subject
stout arms range from 5 to 25 mm. and those of our entire series, a woman weighing 391
from diastolic readings also from 5 to 25 mm. pounds. Her systolic pressure was underesti-
These authors admit that variations in circum- mated by the auscultatory method!
ference of the arm do not account for more than
a quarter of the differences between direct and SUMMARY
indirect readings and doubt the usefulness 1. Simultaneous direct intra-arterial blood
of applying a correction for arm circumference pressure measurements and indirect measure-
to an individual reading. ments with the auscultatory method were made
Our own findings lead us to the same con- in 100 subjects. The subjects were grouped
clusion. Besides, marked overestimation of according to their Ponderal Index W/H, weight
blood pressure by the auscultatory method, in per inch of height. Sixty-one subjects were
our series, was not at all limited to obese sub- obese, thirty-nine were nonobese.
jects, but occurred in lean persons also. Most 2. Nine out of the ten stoutest subjects were
noteworthy, however, is our finding of falsely hypertensive, whereas only one of the ten leanest
high readings in eight out of ten extremely subjects was hypertensive.
obese persons. The overestimations ranged 3. The indirect method generally under-
from 6 to 51 mm. and were greater than the estimates systolic and overestimates diastolic
general range of 10 to 30 mm. reported in the pressure. This holds for lean persons as well as
literature.5*17 Only Trout and associate@ for moderately obese persons.
found discrepancies greater than ours; they 4. The discrepancies between the direct and
ranged from 32 to 102 mm. Hg, with the two indirect methods were usually minor among the
greatest, 80 and 102 mm., occurring in the two lean and the moderately obese subjects and
stoutest arms. went in both directions. Falsely high blood
The accuracy of clinical blood pressure pressure readings in lean and moderately obese
measurement in general depends on many persons are not common.
factors such as age of the subject, height of true 5. In extremely obese persons the indirect
blood pressure, rigidity of arterial wall, contour method is subject to considerable error. In
of pulse wave,22 and sphygmomanometric eight out of ten such persons the systolic pres-
technic6 Obesity is but one such factor and sure was overestimated, and in nine out of ten
only in extremely stout subjects can it become such persons the diastolic pressure was over-
decisive. It is the large size of the arm which is estimated.
responsible for the error. In such persons we 6. Overestimation of systolic pressure in very
found that the difficulty of applying the cuff also obese persons can be much greater than was
plays a part. Often it is difficult to wrap the heretofore known; it amounted to 44, 50 and 51
cotton sleeve evenly around the big arm; not mm. in three of our stoutest subjects.
7. Falsely high readings in extremely obese 8. KEYS, A. and BROZEK, J. Body fat in adult man.
Physiol. Rev., 33: 245, 1953.
subjects are caused by the large size of their
9. DUBLIN, L. J. Relation of obesity to longevity.
arms. If this possibility is borne in mind, an New England J. Med., 248: 971, 1953.
unwarranted diagnosis of hypertension is not 10. ADLERSBERG, D., COIZR, A. R. and LAVAL, J.
likely to be made. In dubious cases, intra- Effect of weight reduction on course of arterial
arterial measurement should be resorted to. hypertension. J. Mt. Sinai Hosp., 12 : 984, 1946.
Il. NUZUM, F. R. and ELLIOT, A. H. An analysis of
8. Many factors other than arm size may
500 instances of arterial hypertension. Am. J.
cause inaccuracies of the indirect method, and M. SC., 181: 630, 1931.
the large arm does not regularly cause falsely 12. ROBINSON,S. C., BRUCES,M. and MASS, J. Hyper-
high readings. It is not feasible to apply a cor- tension and obesity. J. Lab. & Clin. Med., 25:
807, 1940.
rection to an individual reading.
13. TERRY, A. H., JR. Obesity and hypertension. J. A.
M. A., 81: 1283, 1923.
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JULY 1961