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22/6/2015 BaxterShinesaSpotlightonInnovativeandLifeChangingResearchfromYoungScientists

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FEATURES/NEWS
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Sometimesthekeytosolvingacomplexhealthproblemcanbefoundin
events,profilesandother somethingassmallasanotecard.
initiatives.
MEDIACONTACTS That'swhatAbigailWeaverhasbeenprovingthroughthedesignofapaper
basedanalyticaltoolthatcombinescolorproducingchemicalreactionswith AbigailWeaver,agraduatestudentat
Findoutwhotocontactif
papertomakeaninexpensive,portabletestforpharmaceuticals.Thesetest theUniversityofNotreDame,
youareamemberofthe
cardsareabletogeneratea"colorbarcode"thatcanquicklydetermine presentsonherworkindevelopinga
media.
whetherasampleisanauthenticpharmaceuticalorcounterfeit.Testingtakes paperbasedanalyticaltoolthatcan
FACTSHEETSAND onlysixminutes,requiresnolabequipment,andtodatehergrouphas serveasaninexpensive,portable
INFORMATION producedcolorbarcodesfor40differentpharmaceuticalingredients. testtodeterminewhethera
RESOURCES pharmaceuticalsampleisauthenticor
Seeadditionalresources "Poorqualitydrugstendtomaketheirwayintocountriesinturmoil,orin counterfeit.
forthemediasuchasfact settingswithlooseregulationsorlimitedresources,wherechallengescan
sheets,presskitsand includeunreliableaccesstopowerandlackoftrainedpersonnel,"explained
otherinformation. Weaver,agraduatestudentattheUniversityofNotreDame."Wefeelthatthere
arewaystobringchemicalanalysisoutofthelabtomeetrealworldproblems
POSITIONS/POLICIES wheretheyexist."
Readourpositionson
varioustopics. WeaverisoneofsixemergingscientiststhatBaxterrecentlyrecognizedas
recipientsoftheBaxterYoungInvestigatorAward,createdtostimulateand
SUSTAINABILITY
rewardresearchapplicabletothedevelopmentoftherapiesandmedical
ReadourSustainability
Reportandthelatestnews productsthatsaveandsustainpatients'lives.Theawardees,whoeachreceive
a$2,000cashprize,wereinvitedtoBaxter'sRoundLake,Ill.,campusto HangRen,JooKang,Ph.D.,Michael
aboutourinitiatives. VanNiewenhze(onbehalfofErkin
presenttheirresearchtoBaxterscientistsandexecutivesandtoberecognized
INVESTORSRELATIONS attheawardsceremony. Kuru),PratikRanderia,Abigail
Readourannualreport, WeaverandShudiptoDishari,Ph.D.
proxystatementsand "Ms.Weaver'sapplicationwasimpressiveonanumberoflevels,"shared wererecentlypresentedwithBaxter's
DennisJenke,oneofBaxter'sDistinguishedScientists,whohasabackground YoungInvestigatorAwardsfortheir
otherfinancialinformation.
inthefieldofplastic/solutioncompatibility."Shewasabletosimplifythe researchrelatedtothedevelopment
oftherapiesandmedicalproducts
complex,developapplicabletechnologiesthatsupportanappropriatelevelof
thatsaveandsustainpatients'lives.
medicalcarethroughouttheglobalcommunity,andusethosetechnologies
duringherextensivefieldtestinginKenya.Thisaccomplishmentembodies
Baxter'sownprioritiesandcommitmenttoexpandingaccesstocare."

Toselecttheawardwinners,Baxterevaluatescandidatesbasedonseveral
criteria,includingthequalityoftheresearchitself,whethertheindividualhas
publishedhisorherworkinareputablejournalasafirstnamedauthor,has
scientificmediacoveragecommendingthework,orhasmadesignificant
stridesingoingbeyondtheconfinesofpriorworkoftheirresearchgroupby
novelcollaborationsorintroductionsofnewperspectives.

"Withthisaward,we'relookingforknockyoursocksoffinnovationthathasthe
potentialtoimpactclinicaltherapeutics,"saidBarrettRabinow,oneofBaxter's
DistinguishedScientists,whohasabackgroundindrugdelivery,
pharmaceuticalmodelingandnanotechnology,andspokeattheawards
ceremony."Itprovidesanavenuetoidentify,meet,reward,andpotentially
recruittheoutstandingtalentresponsibleforthisresearch.Anditprovidesan
enrichingeducationalopportunityforourownscientificcommunity."

Otherwinnerspresentedonadiversearrayofprojects.JooKang,Ph.D.,
HarvardUniversity,presentedonanextracorporealbloodcleansingbiospleen
forsepsistherapyShudiptoDishari,Ph.D.,PennsylvaniaStateUniversity,
focusedherresearchonunderstandingvirusretentionbehaviorofvirus
filtrationmembranesandErkinKuru,IndianaUniversity,wasrecognizedfor
researchintoapplyingdesignermoleculestobacterialsurfacesthatenable
themtobecomeflorescentandmoreeasilyobserved.HangRen,Universityof
Michigan,presentedonanelectrochemicalnitricoxidereleasesystemthat
improveshemocompatibilityandreducesbacterialbiofilmformationon
biomedicaldevices,addressingtheissueofcatheterrelatedbloodstream
infectionsthatcanresultinasmanyas28,000deathsandincreased
healthcarecostsofupto$2.3billionperyear.PratikRanderia,Northwestern
University,investigatedhowtopicallyappliedsphericalnucleicacid(SNA)
goldnanoparticleconjugatescanhelpincreasewoundhealinginthosewith

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22/6/2015 BaxterShinesaSpotlightonInnovativeandLifeChangingResearchfromYoungScientists
diabetes.

"Thisaddressesabigproblemthereareapproximately20millionpeoplein
theU.S.whohaveType2diabetes,whoseskintakesmuchlongertoheal
whenwounded.In2010,morethan70,000amputationsintheU.S.alone
neededtobeperformed,"saidRanderia,agraduatestudentwithinChad
Mirkin'slaboratoryatNorthwestern."Ourapproachshoweddramatically
acceleratedwoundhealinginmice,andinadditiontopossiblybenefitting
thosewithdiabetes,wefeelthatSNAshavepotentialinavarietyofdifferent
skindisorders."

RabinownotesthatRanderia'sresearchissignificantasitaddressesamajor
medicalneed."Thisisanovel,practicalwayforgettingDNAtypetherapies
intothecell,potentiallypavingthewayforanexcitingeraofawholenewclass
ofpromisingdrugs,"hesaid.

Inadditiontothesixfirsttierwinners,11youngscientistswereselectedas
secondtierwinnersandawarded$500each(seefulllisthere).Theirresearch
alsopertainedtoinstrumentalandanalyticalsciences,lifesciences,medical
deviceengineering,orpharmaceuticalsciences,withemphasisonthe
potentialoftheresearchtosaveandsustainlives.Throughtherecognition
program,Baxterhopestohelptheseupandcomingresearchersadvance
theirprojectsandcareersandcontinuedownapathofscientificdiscoverythat
canultimatelyleadtoaddressingimportanthealthcareneeds.

"Ifwecanidentify,encourageandnurturepromisingyoungscientistsearlyin
theircareer,thenweincreasethelikelihoodthatthesehighachieverswill
realizetheirfullpotentialandproduceoutcomesthataretrulysignificantfor
mankindandwhichimprovethehumancondition,"saidJenke."It'smyhope
thatoneday,aYoungInvestigatorwillgoontoadistinguishedcareerinthe
sciencesthatculminatesinbecomingaNobelLaureate."

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