PHARMACOLOGIC MANAGEMENT

DRUG NAME EFFICACY SUITABILITY SAFETY AFFORD

ABILITY
Insulins
Regular Insulin Insulin and its analogues lower Type 1 DM, Type 2 Headache, influenza-like symptoms, dyspepsia, P1200/via
blood glucose by stimulating DM, DKA, diarrhea, back pain, pharyngitis, hypoglycemia, l
peripheral glucose uptake, Hyperkalemia, Short insulin resistance, lipodystrophy,
especially by skeletal muscle bowel syndrome lipohypertrophy, local allergic reactions,
Rapid-acting: Lispro, and fat and by inhibiting hepatic Type 1 DM, Type 2 hypokalemia P814/pen
aspart, glulisine glucose production; insulin DM or
inhibits lipolysis and proteolysis cartridge
Intermediate-acting: and enhances protein synthesis; P755/vial
NPH/Lente targets include skeletal muscle,
Long-acting: liver and adipose tissue P750.34/p
Glargine, detemir en
Antithyroid Agents/ Thioamides
Propylthiouracil Inhibit thyroid peroxidase Hyperthyroidism, Nausea, gastrointestinal disturbances, rash, P643.50/t
reactions, iodide organification, Graves, Thyrotoxic agranulocytosis, hepatitis, hypothyroidism ab
Methimazole and peripheral conversion of T4 Crisis P6.25/5m
to T3 g tab
P20/
20mg tab
P-DRUGS
Insulin
Regular Insulin Insulin and its analogues lower Type 1 DM, Type 2 Headache, influenza-like symptoms, dyspepsia, P1200/via
blood glucose by stimulating DM, DKA, diarrhea, back pain, pharyngitis, hypoglycemia, l
peripheral glucose uptake, Hyperkalemia, Short insulin resistance, lipodystrophy,
especially by skeletal muscle bowel syndrome lipohypertrophy, local allergic reactions,
and fat and by inhibiting hepatic hypokalemia
glucose production; insulin
inhibits lipolysis and proteolysis
and enhances protein synthesis;
targets include skeletal muscle,
liver and adipose tissue
Antithyroid Agents/ Thioamides
Methimazole Inhibit thyroid peroxidase Hyperthyroidism, Nausea, gastrointestinal disturbances, rash, P6.25/5m
reactions, iodide organification, Graves, Thyrotoxic agranulocytosis, hepatitis, hypothyroidism g tab
and peripheral conversion of T4 Crisis P20/
to T3 20mg tab