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Pharmacology Test 1 Drug List
Alphabetical
Sulfonylurea
Acetylcholine Cholinergic Agonist, Direct LOW DOSE: Stimulate NO, vasodilation, reflex
tachycardia
Muscarinic
HIGH DOSE: Vasodilation, direct bradycardia.
Choline ester
Extremely short-half life in-vitro due to
abundant cholinesterase.
beta2-selective
NE-Potentiating Agent
Amphetamine
Muscarinic
Choline ester
Muscarinic Antagonist
4 Amine
Muscarinic Antagonist
3 Amine
Long-acting
Short-acting
NE-depleting agent
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Bromocriptine Hormone Dopamine agonist ------> suppress Prolactin.
Used to treat hyperprolactinemia.
Prolactin Antagonist
Dopamine Agonist
Calcium-regulation
Choline ester
Direct application in eye: used to treat non-
congestive wide-angle glaucoma.
Dopamine-Decarboxylase
Inhibitor
Thionamide
beta-Antagonist, non-selective
Sulfonylurea
NE-Potentiating Agent
MAO Inhibitor
Uptake I Inhibitor
Curare (d-Tubocurarine) Cholinergic Antagonist, Direct Prototypical NMJ Antagonist. Causes flaccid
paralysis of skeletal muscle.. It only blocks
Nicotinic Blocker the NMJ -- not other nicotinic receptors, and
not muscarinic!
Blocks Neuromuscular
Junction
Muscarinic Antagonist
3 Amine
NE-Potentiating Agent
MAO Inhibitor
Long-acting
Dobutamine Adrenergic Agonist, Direct Displays some alpha1 effects. Used for
cardiogenic shock and CHF.
"Cardioselective" (B1)
Increases the inotropic state, with little effect
on heart-rate or TPR (because it is modulated
by alpha1 agonist).
alpha-Antagonist, alpha1-
Selective
Cholinesterase Inhibitor
Organophosphate
(Irreversible)
Ephedrine Adrenergic Agonist, Indirect Taken orally, long duration of action. Used in
asthma, as nasal decongestant, and
Mixed-receptor agonist sometimes as a pressor.
Sulfonylurea
Muscarinic Antagonist
4 Amine
NE-depleting agent
Hexame thonium Cholinergic Antagonist, Direct Prototypical ganglionic blocker. Blocks all
autonomic reflex responses (generally, a
Ganglionic Blocker reflex tachycardia or bradycardia)
Blocks NGreceptors
Muscarinic Antagonist
3 Amine
Short-acting
NE-Potentiating Agent
Muscarinic Antagonist
4 Amine
beta2-selective
Cholinesterase Inhibitor
Organophosphate
(Irreversible)
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Isophane (NPH) Insulin Diabetes Cloudy solution. Protease reacts with the
protamine to release the insulin. Later onset
Insulin and longer duration.
Intermediate-acting
Intermediate-acting
Organophosphate
(Irreversible)
Nicotinic Blocker
Estrogen
beta2-selective
Amphetamine
Muscarinic Antagonist
4 Amine
Amphetamine
Alkaloid
GnRH Analogue
Neostigmine Cholinergic Agonist, Indirect Has a quaternary nitrogen and does enter
CNS.
Cholinesterase Inhibitor
Can be used to treat Myasthenia Gravis.
Carbamate (Reversible)
Intermediate-acting
Cholinesterase Inhibitor
Organophosphate
(Irreversible)
NE-Potentiating Agent
MAO Inhibitor
Amphetamine
beta-Antagonist, non-
selective
Amphetamine
Physostigmine Cholinergic Agonist, Indirect Is a tertiary nitrogen and does enter CNS.
It is therefore used in treatment of Atropine
Cholinesterase Inhibitor poisoning.
Carbamate (Reversible)
Muscarinic
Alkaloid
beta2-selective
Muscarinic Antagonist
3 Amine
Short-acting
Prolactin
Muscarinic Antagonist
4 Amine
Pseudoephedrine Adrenergic Agonist, Indirect Taken orally, long duration of action. Used
in asthma, as nasal decongestant, and
Mixed-receptor agonist sometimes as a pressor.
Ritodrine Adrenergic Agonist, Direct Used to relax the uterus during labor.
beta2-selective
Cholinesterase Inhibitor
Organophosphate
(Irreversible)
3 Amine
Cholinesterase Inhibitor
Organophosphate
(Irreversible)
Choline ester
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Tabun Cholinergic Agonist, Indirect
Cholinesterase Inhibitor
Organophosphate
(Irreversible)
alpha-Antagonist, alpha1-
Selective
beta2-selective
Anti-Thyroid
Ionic Inhibitor
Sulfonylurea
Sulfonylurea
MAO Inhibitor
Intermediate-acting
Muscarinic Antagonist
3 Amine
Ganglionic Blocker
Blocks NGreceptors
Muscarinic Antagonist
3 Amine
Long-acting
alpha1, alpha2