Sie sind auf Seite 1von 2

Hypertension Research

3
In Pregnancy K. Watanabe et al.

SOCIETY STATEMENT Key words:


definition, pregnancy induced
hypertension, preeclampsia

Outline of Definition and


Classification of Pregnancy induced
Hypertension (PIH)
Kazushi Watanabe1, Katsuhiko Naruse2, Kanji Tanaka3,
Hirohito Metoki4, Yoshikatsu Suzuki5

1
Department of Obstetrics and Gynecology, Aichi Medical University School of Medicine,
2
Department of Obstetrics and Gynecology, Nara Medical University, 3Department of
Obstetrics and Gynecology, Hirosaki University, 4Department of Obstetrics and
Gynecology and Tohoku Medical Megabank Organization, Tohoku University, 5Department
of Obstetrics and Gynecology, Nagoya City West Medical Center

In this report, we present the terminology, definition and classification of pregnancy induced hypertension (PIH) by the
Japan Society for the Study of Hypertension in Pregnancy (JSSHP). PIH is classified as gestational hypertension (GH),
preeclampsia (PE), superimposed preeclampsia (S-PE) or eclampsia (E). Subclassifications by symptoms (severity and
gestational age at onset) are also shown.

Terminology but both symptoms normalize by 12 weeks postpartum.

In 2004, Toxemia of Pregnancy was revised to Superimposed preeclampsia (S-PE)


Pregnancy induced Hypertension (PIH) in Japan.1,2) Superimposed preeclampsia is diagnosed in the following
three cases. (1) New onset proteinuria ( 300 mg/24
Definition hours) in hypertensive women who exhibit no proteinuria
before 20 weeks gestation. (2) Hypertension and
PIH is defined as hypertension (blood pressure 140/90 proteinuria documented antecedent to pregnancy and/or
mmHg) with or without proteinuria ( 300 mg/24 hours) detected before 20 weeks gestation, one or both of which
emerging after 20 weeks gestation, but resolving up to 12 progressing after 20 weeks gestation. (3) Renal disease
weeks postpartum.110) PIH is also defined as new onset with proteinuria documented antecedent to pregnancy
proteinuria ( 300 mg/24 hours) in hypertensive women and/or detected before 20 weeks gestation, which is
who exhibit no proteinuria before 20 weeks gestation. accompanied with new onset hypertension after 20 weeks
gestation.
Classification
Eclampsia (E)
Gestational hypertension (GH) Eclampsia is defined as the onset of convulsions in a
GH is diagnosed in women whose blood pressure reaches woman with PIH that cannot be attributed to other causes.
140/90 mmHg for the first time during pregnancy The seizures are generalized and may appear before,
(after 20 weeks gestation), but without proteinuria. Blood during, or after labor.
pressure normalizes by 12 weeks postpartum.
Subclassification by symptoms
Preeclampsia (PE) *Severity*
Hypertension (blood pressure 140 / 90 mmHg) The severity of PIH is assessed by the extent of
accompanied with proteinuria exceeding 300 mg/24 symptoms. Both blood pressure and proteinuria are
hours emerges for the first time after 20 weeks gestation, dependable indicators of severity.

2013 The Authors


Hypertens Res Pregnancy 2013; 1: 34 3
Hypertension Research in Pregnancy 2013 Japan Society for the Study of Hypertension in Pregnancy
Definition of PIH in JSSHP

Mild PIH 5. Nelson TR. A clinical study of preeclampsia. J Obstet Gynaecol Br


Blood pressure is 140/90 mmHg but < 160/110 Emp. 1955; 62: 48 66.
mmHg after 20 weeks gestation, and proteinuria is 300 6. Friedman EA, Neff RK. eds. Pregnancy Hypertension. A Systemic
Evaluation of Clinical Diagnosis Criteria. Littleton, MA: PSG
mg/24 hours without exceeding 2.0 g/24 hours or 3 +
Publishing Co, 1997; 64.
dipstick.3,4,10,11)
7. Stone P, Cook D, Hutton J, Purdie G, Murray H, Harcourt L.
Severe PIH Measurement of blood pressure, oedema, and proteinuria in a
Blood pressure is 160/110 mmHg, and proteinuria pregnant population of New Zealand. Aust N Z J Obstet Gynaecol.
exceeds 2.0 g/24 hours or 3 + dipstick.11,12) 1995; 35: 32 37.
*Classification by onset* 8. MacGillivary I, Rose GA, Rowe B. Blood pressure survey in
PIH that emerges earlier than 32 weeks gestation is pregnancy. Clin Sci. 1969; 37: 395 407.
referred to as early onset (EO) type, and PIH that emerges 9. Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin
after 32 weeks gestation is referred to as late onset (LO) JM. The classification and diagnosis of the hypertensive disorders
type.1315) of pregnancy: statement from the International Society for the
Study of Hypertension in Pregnancy (ISSHP). 2001; 20: IXXIV.
10. Brown MA, Hague WM, Higgins J, et al. The detection,
Appendix investigation and management of hypertension in pregnancy: full
consensus statement. Aust N Z J Obstet Gynaecol. 2000; 40:
Pulmonary edema, stroke, and HELLP syndrome are 139 155.
considered severe variants, and are excluded from the 11. Report of the National High Blood Pressure Education Program
definition or classification of PIH. Working Group on High Blood Pressure in Pregnancy. Am J Obstet
Gestational proteinuria and edema are excluded from Gynecol. 2000; 183: S1 S22.
PIH symptoms. 12. Paller MS, Connaire JJ. The kidney and hypertension in pregnancy.
In: Brenner BM. ed. Brenner & Rectors the Kidney, 7th ed.
References Philadelphia: Saunders, 2004; 1659 1695.
13. Hidaka A, Nakamoto O, Eguchi K, Furuhashi N, Yamaguchi K.
1. Japan Society for the Study of TOXEMIA OF PREGNANCY. ed. Classification by onset of toxemia of pregnancy and period from
Historical Perspective of Study of Pregnancy-Induced Hypertension mild to severe in the each pathogenesis.: Investigation report in
in Japan. Tokyo: Medical View Co., Ltd., 2005. (In Japanese.) severe toxemia of pregnancy. Journal of Japan Society for the Study
2. Japan Society for the Study of Hypertension in Pregnancy. ed. of Toxemia of Pregnancy. 1998; 6: 155 214. (In Japanese.)
Guideline 2009 for care and treatment of hypertension in pregnancy 14. Hidaka A, Nakamoto O, Eguchi K, Furuhashi N, Satoh K. Each
(PIH). Tokyo: Medical View Co., Ltd., 2009. (In Japanese.) branch point and maternal background viewed from a different
3. National High Blood Pressure Education Program Working Group incidence of severe gestational hypertension and proteinuria.
Report on High Blood Pressure in Pregnancy. Am J Obstet Sanfujinka Chiryo. 2003; 87: 467 473. (In Japanese.)
Gynecol. 1990; 163: 1691 1712. 15. Yamasaki M, Nakamoto O, Suzuki Y, et al. Validation of the
4. North RA, Tayler RS, Schllenberg JC. Evaluation of a definition of gestational week dividing border for subclassifying pregnancy
preeclampsia. Br J Obstet Gynaecol. 1999; 106: 767 773. induced hypertension. Hypertens Res Pregnancy. 2013; 1: 2330.

4 Hypertens Res Pregnancy 2013; 1: 34

Das könnte Ihnen auch gefallen