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CHAPTER 3 PARASITOLOGY
1. (Answer: c).Toxocara canis eggs are dark brown, thick-walled eggs with a pitted eggshell (c). Clear,
smooth, and thin-walled eggs (a) would be associated with hookworm infection. Yellow-brown thick-
walled eggs with striated shells and asymmetrical plugs (b) describes the diagnostic stage of the
Eucoleus bohmi. Finally, L1 with S-shaped tail lacking a dorsal spine (d) describes the diagnostic
developmental stage of the canine lungworm.
2. (Answer: a).Ancylostoma caninum causes (and is thus contracted by) cutaneous (a) larval migration.
Ancylostoma caninum must mature and molt in the environment before it achieves its infective stage,
so it does not spread by rectal remigration (b), and neither mosquitoes (c) nor fleas (d) spread
Ancylostoma caninum.
3. (Answer: d). Fleas (d) incubate and are the intermediate hosts for Dipylidium caninum. Squirrels (a)
are intermediate hosts of Taenia pisiformis. Ticks (b) do not transmit tapeworms. Cows (c) are
intermediate hosts of Taenia hydatigena.
4. (Answer: a). The prefix oto-is your clue that this is an ear infestation. Head tilt, otitis media
circling, and seizures (a) are all signs of a severe infection of Otodectes cynotis. Head shaking and ear
scratching (b) are signs of a less severe infection. Thickened, wrinkled skin with eventual physical
emaciation (c) is seen in severe (even fatal) infection with a less common ear mite, Psoroptes spp., and
is not usually seen in dogs. Finally, severe tail, leg, or scrotal mange (d) is the sign of infection with
Chorioptes spp., which is also not usually seen in dogs.
5. (Answer: b).Ixodes scapularis is the host to Borrelia burgdorferi (Lyme disease) (b). Rocky Mountain
spotted fever (a), tularemia (c), and Q fever (d) are spread by Dermacentor spp.
6. (Answer: d). Although mainly seen in animals, the flea can be swallowed by humans and thus the
Dipylidium caninum tapeworm (d) can mature in a human host, whereas Cystoisospora canis and
Trichuris vulpis (a and b) are specific to dogs and Parascaris equorum (c) is specific to horses.
7. (Answer: d). Mallophaga (d) are the biting or chewing lice, whereas Anoplura (b) are sucking lice.
Hemiptera (a) are true bugs such as reduviid bugs, and Diptera (c) are the two-winged flies.
8. (Answer: a).Aelurostrongylus abstrusus (feline lungworm) (a) is best diagnosed using the Baermann
test. The others (b, c, and d) are diagnosed by fecal flotation or centrifugal flotation.
9. (Answer: a). One of the great advantages of centrifugal flotation technique is to (a) detect Giardia
oocysts and Trichuris ova more efficiently than with the regular flotation technique. Direct smear is
used to detect protozoa in feces (b), and the number of eggs present per gram of feces (c) requires
quantitative procedures such as the Wisconsin double centrifugation technique and the McMaster
technique. Finally, the standard vial gravitation flotation technique is based on specific gravity of
parasitic material and fecal debris (d).
10. (Answer: c).Oxyuris equi (c) can be lifted off the skin surface using cellophane tape and then taped over
a drop of mineral oil on a slide for visual examination. This is because they are found primarily on the
skin surface and the hair. Thelazia californiensis (a) is found in the conjunctival sac of the eye or in the
tear duct, and Eimeria spp. and Balantidium coli are both intestinal and found in feces (b and d).
11. (Answer: b).Cheyletiella species (b) are referred to as walking dandruff because they resemble
flakes of moving dandruff. Reduviid bugs (a) are referred to as kissing bugs, and Culicoides
spp. (c) are referred to as no-see-ums. Glossina species are referred to as tsetse flies.
12. (Answer: d). The hexacanth is the infective stage of a tapeworm (d). Ticks and mites (a and b) are
visible as adult insects. Pinworms (c) are usually seen in egg form.
13. (Answer: c).Giardia and Leishmania are examples of flagellates (c). Protozoa are one-celled microscopic
parasites that are sometimes classified by movement; in addition to the flagellates, they include ameba
(a), ciliates (b), and sporozoa (d).
14. (Answer: c). The Baermann technique (c) is used to remove lungworm larvae from small amounts of
feces. Centrifugation (a) and McMaster (b) techniques are each used to determine the number of eggs
present per gram of feces; the direct smear technique (d) is used to detect protozoa in feces and
quickly estimate their number.
15. (Answer: c). Tapeworms are cestodes (c). Like flukes (trematodes) (d), they fall into the flatworm
subcategory of the helminths. Nematodes (b) are roundworms, and thorny-headed acanthocephalins
(a) are thought to be intermediate between cestodes and nematodes.
16. (Answer: b). The Knotts test differentiates the blood parasite Dirofilaria immitis from the
nonpathogenic filarial larvae Acanthocheilonema (b). The test is specific to these two and not to the
others (a, c, and d).
17. (Answer: d). Fleas are found on the hosts skin during the adult stage (d) of the life cycle. The
larvae (b) and pupae (a) are found in the bedding and living area of the host.
18. (Answer: a). The prepatent period for Trichuris vulpis is (a) 3 months. Hookworms prepatent
period is 2 weeks (b), and that for Filaroides spp. is 5 to 10 weeks (c). Spirocerca lupi have a prepatent
period of 5 to 6 months (d).
19. (Answer: c). In sucking lice, the head is narrower than the thorax (c). The rabbit fur mite, Listrophorus
gibbus, has a body that is laterally compressed, with a broad head (a). Scutum ornate and basis
capitulum (b and d) both describe the hard tick.
20. (Answer: a).Hyostrongylus rubidus is the red stomach worm of pigs (a). Physaloptera spp. is a stomach
worm of the cat or dog (b and c), and Gasterophilis spp. is a stomach parasite of the horse (d).
but it is involved in acid-base balance and is therefore not evaluated with the other electrolytes.
Phosphorus (b) is one of the major intracellular electrolytes, and sodium (d) is one of the major
extracellular electrolytes. Albumin (c) is a plasma protein not an electrolyte.
18. (Answer: b). Sodium and chloride levels have a close relationship (b), and each plays a major role in
the distribution of water and the maintenance of osmotic pressure of fluids in the body. Calcium and
phosphorus (a) are involved primarily in bone formation and maintenance, and magnesium and
potassium (c) are intracellular electrolytes and have little effect on fluid balance in the extracellular
space. Calcium works predominately with phosphorus, not chloride (d).
19. (Answer: c). RIM testing (c), which stands for rapid immunomigration testing, has also been called lateral
flow immunoassay, or immunochromatography. TLI (a) refers to trypsinlike immunoreactivity assay;
ELISA testing (b), or enzyme-linked immunosorbent assay, is an accurate way to detect specific
antigens or antibodies such as viruses, bacteria, parasites, or hormones in serum and plasma. Latex
agglutination testing (d) uses small, spherical latex particles coated with antigen suspended in water;
with positive samples, formation of an antibody-antigen complex occurs and is seen as agglutination.
20. (Answer: a). Triglycerides (a) are the fat fraction most responsible for lipemic blood samples, often as a
result of diet, metabolic disease, or inadequate fasting. Lipase and amylase are enzymes (b and c), not
fats; and cholesterol (d) is a clear fat, whereas lipemic serum is cloudy.
CHAPTER 5 CYTOLOGY
1. (Answer: d). Methanol 95% (d) is the preferred fixative for most cytology preparations. Tissue
samples for histopathological examination are usually fixed in 10% neutral buffered formalin (a).
Phosphate (b) is not used as a fixative, and EDTA (c) in saline is used with marrow smears.
2. (Answer: b). The fatty material in chylous effusions (b) interferes with light passage through the
refractometer, whereas color of samples (a) may vary and samples from a hemorrhagic area (c) will
not have a great effect on assessing total protein with a refractometer. If a sample is characterized as a
transudate (d), this does not affect the refractometers ability to accurately weigh total solids.
3. (Answer: c). Rayon swabs (c) are preferred over cotton because cotton, whether on a swab, a cotton
ball, or an applicator stick (a, b, and d), can inhibit bacterial growth and oxygen can become trapped
in the fibers, inhibiting the recovery of anaerobic bacteria.
4. (Answer: c). The patient is usually standing or in ventral (c) recumbency for removal of pleural fluid.
Dorsal or lateral recumbency (a and b) is better for cystocentesis, and lateral or sternal recumbency (b
and d) is used for removal of pericardial fluid.
5. (Answer: a). The modified compression smear (a) subjects cells to lower shear forces than the
standard compression (c) preparation. A starfish smear (b) is most useful for highly viscous samples,
and a wedge smear (d) is used with aspirate smears to produce a film similar to that used for a whole
blood differential count.
6. (Answer: b). The starfish smear (b) allows spreading of cells in a viscous sample that would not
spread with a standard compression (c) or modified compression (a) preparation. A wedge smear (d)
is used with aspirate smears to produce a film similar to that used for a whole blood differential count
7. (Answer: c). Cytology samples require increased fixative times in contrast to blood films. The
prepared cytology slides should remain in the fixative for at least 2 to 5 minutes (c). A range of 30 to
60 seconds (a and b) is not long enough, and 10 minutes (d) is not the required minimum; longer
fixative times will improve the quality of the staining procedure and will not harm the samples.
8. (Answer: b). New methylene blue (b) will stain nuclei, mast cell granules, and most infectious agents.
Gram stains (d) work better with gram-negative and gram-positive organisms, which each stain a
different color. Mast cell granules may not stain with Romanowsky stains such as Giemsa (a) or Diff-
Quik (c).
9. (Answer: b). The term karyorrhexis (b) describes a fragmented nucleus. Pyknosis (a) describes a
condensed nucleus; karyolysis (c) refers to a loss of nuclear membrane, and hypersegmentation (d)
refers to a nucleus with more than five lobes.
10. (Answer: d). Mesothelial cells (d) are characterized by a fringe border, or corona, and finely reticulated
nuclear chromatin. Mast cells (a) are round to oval, and macrophages (b) are oval to pleomorphic with
lacy to condensed chromatin. Plasma cells (c) are oval with an eccentric nucleus, a basophilic
cytoplasm, and a perinuclear clear zone.
11. (Answer: d). Granulomatous inflammation (d) is characterized by the presence of more than 70%
mononuclear cells and few neutrophils, a pyogranulomatous inflammation (a) consists of
macrophages and 50% to 75% neutrophils, and a purulent inflammation (b) has more than 85%
neutrophils. An eosinophilic inflammation (c) consists of greater than 10% eosinophils, but few mast
cells, plasma cells, and lymphocytes.
12. (Answer: c). Hyperplasia (c), or benign neoplasia, is characterized by homogeneous populations of the
same cell type with no evidence of malignant characteristics within cells. The other
threeaniscocytosis, macrocytosis, and pleomorphism (a, b, and d) are all criteria for malignancy.
13. (Answer: b). A hematoma (b) is a noninflammatory and non-neoplastic lesion, whereas histiocytoma,
TVT, and mesenchymal (a, c, and d) are all types of neoplastic tumors.
14. (Answer: a). Malassezia (a) is a common fungus recovered from ear cytology samples. Otodectes (b) is a
parasite found in the ear. Simonsiella (c) is normal bacterial mouth flora, and Blastomyces (d) is a fungal
inflammation found in the lungs.
15. (Answer: c).Simonsiella (c) is normal flora of the oral cavity. Malassezia (a) is a common fungus
recovered from ear cytology samples. Otodectes (b) is a parasite found in the ear. Blastomyces (d) is a
fungal inflammation found in the lungs.
16. (Answer: a). A variety of cell types are present in a normal (a) lymph node, including plasma cells,
macrophages, and small, medium, and large lymphocytes, but with a majority (75% to 90%) of small
lymphocytes. Neoplastic findings (b) would show lymph node cells with abnormal nuclear features or
presence of a large number of blast cells. Inflammation (c) would show an increase in neutrophils,
eosinophils, and macrophages. Finally, a metastatic sample (d) would show neoplastic cells from other
body tissues that spread to lymph nodes.
17. (Answer: a). Hematoxylin and eosin stain (a) is preferred for core biopsy samples. New methylene
blue (b) will stain nuclei, mast cell granules, and most infectious agents. Papanicolaou stain (c) is
commonly used in human gynecological examinations. Giemsa stain (d) provides satisfactory staining
of cytological specimens.
18. (Answer: a). Increased numbers of mature lymphocytes (a) is a characteristic of chylous effusion.
Lymphoblasts (b) are immature lymphocytes; and macrophages (c) are large phagocytic WBCs in
blood, lymph, and connective tissue. Polychromatophilic rubricytes are a type of nucleated RBC (d).
19. (Answer: b). A variety of cell types are present in vaginal cytology samples collected during proestrus
(b), including RBCs and parabasal, intermediate, and superficial epithelial cells. An estrus sample (a)
contains all superficial cells, with many appearing to be anuclear or with small pyknotic nuclei. RBCs
may be present, but no neutrophils. A metestrus (c) sample shows parabasal and intermediate cells
replacing superficial cells. Neutrophils increase and RBCs are usually absent. An anestrus sample (d)
is made up predominantly of noncornified squamous epithelial cells and some neutrophils, but no
RBCs.
20. (Answer: b). The nonaspiration method is the preferred sample collection method for vascular
samples (b) such as the liver and spleen. A type of fine-needle procedure, it is also referred to as the
capillary technique or stab technique because it uses a needle or a syringe without the plunger
attached to a needle. That means that it is not as useful for solid, fatty, or fibrinous sample collection
(a, c, and d).
CHAPTER 7 RADIOGRAPHY
1. (Answer: b). As a wavelength increases, the frequency decreases (b), not the reverse (a). Frequency
and wavelength are inversely proportional, so a change in one does affect the other (making c and d
untrue).
2. (Answer: a). Ionizing electromagnetic radiation is characterized by the energy contained in a photon
(a). Ionization is a type of energy transfer induced by causing x-rays to interact with matter (b);
inappropriate exposure can result in tissue damage (c). An x-ray is a penetrating, ionizing
electromagnetic radiation that has a wavelength much shorter than that of visible light, not longer (d).
3. (Answer: c). X-rays form a heterogeneous beam, not a homogeneous beam (c) that travels in a
straight line, not a wavy one (c). They are electrically neutral and have no mass (d) and can penetrate
living tissue (a), causing some substances to fluoresce (b).
4. (Answer: d). Bremsstrahlung and braking radiation are the same thing (d) and make up most x-rays
in the diagnostic range. Bremsstrahlung (or braking) radiation (a and b) occurs when an incoming
projectile electron moves very close to the nucleus, losing energy as it passes. Characteristic radiation
(c) occurs when the energy of a projectile electron interacts with a K-shell electron and removes it
from its orbit.
5. (Answer: b). The kilovoltage (kV) controls contrast (b). At lower kV, the photoelectric effect results in
total absorption of the energy of the incoming x-ray photon, meaning both the absorbed dose and the
contrast increase at lower kV. The quantity of radiation in milliamperage per second is represented by
the abbreviation mAs (a). SID (c) or source-image distance affects magnification and detail. RAD (d)
stands for radiation absorbed dose and measures the energy transferred by radiation to a body part.
6. (Answer: a). When film density is too light and the technician suspects that the problem is related to
exposure time (mAs), doubling the density from 10 mAs to 20 mAs means a change to 200 mA per
0.10 second or 20 mAs (a) while (b) does not double the mAs. If you increase both kV and mAs (c and
d) you are more than doubling the density plus you are decreasing the contrast with the change in kV.
7. (Answer: a). An increase in SID and a decrease in SOD (a) help minimize magnification and
penumbra. An increase in the source-object distance (b and c) would cause more magnification and
penumbra, and likewise, a decrease in SID (c and d) increases magnification.
8. (Answer: d). The heel effect is most noticeable when using largest film size (a and b) and a short
source-image distance (SID) (a and c). Thus a smaller film and longer SID (d) will help make the heel
effect less noticeable.
9. (Answer: c). Increasing film speed increases the darkness of the image (c), not the other way around
(b). Use of a grid not compensated for would make the film lighter (a), and improper stirring of
solutions causes reticulation (d) (a network of wrinkles resulting from sharp temperature differences
in the solutions).
10. (Answer: c). A functional safelight will process to a density of 0.50 or very light silver gray (c), as
opposed to streaked, totally dark, or clear (a, b, and d).
11. (Answer: a). During development, agitation (a) during the developer fixer process ensures that fresh
chemistry is moved onto the film and used chemicals are moved away from the film. Developer (c)
primarily functions to reduce, or convert, the exposed silver halide crystals of the film emulsion to
black metallic silver. The fixers primary functions (b) are to remove and clear away the
unexposed, undeveloped silver halide crystals and harden the film to make it a permanent record.
Although proper time-temperature is important (d), only by agitating the film can fresh chemicals be
moved over the film and used chemicals be moved away from it.
12. (Answer: d). The phosphors used today primarily emit in the yellow-green light part of the spectrum
(d) not in the blue-green part of the spectrum (a). There is greater x-raytolight conversion with
current phosphors, not minimal x-raytolight conversion (b), resulting in decreased exposure
factors (not increased exposure factors [c]) required to produce the same density on a film.
13. (Answer: d). The lateral along with the craniocaudal view (d) are the best views of the canine elbow.
The patient is lying in ventral recumbency so the term for the elbow is the craniocaudal view. In this
position it would be called dorsopalmar view (a) for the carpus, metacarpus, and digits, while the
plantarodorsal (b) is the term for the metatarsus and corresponding digits. The caudocranial (c) is the
term, used for the shoulder, scapula and humerus, when the patient is lying in dorsal recumbency.
14. (Answer: a). In an accurate view of the elbow, the cranial border should be the distal third of the
humerus, with the caudal border at the proximal third of the radius or ulna (a). The junction of the
femur and tibia or fibula (b) would indicate the hind leg rather than the forelimb. Including two thirds
of the bones distal and proximal (c) could adversely affect the resultant image, and borders consisting
of the carpus and ulna or radius (d) would focus on the wrong joint entirely.
15. (Answer: c). The big three tenets of radiation safety include minimum time settings for the
examination, combined with keeping as far as possible from the x-ray beam, and always using
shielding (c). Conversely, you would increase your risk for harmful effects if you consistently used
maximum time settings (a and b), stayed as close as possible to the patient and beam (a), and neglected
constant use of protective apparel (d).
16. (Answer: b). Contrast is increased at a lower kV (d) and with the use of a grid (a), with the collimator
aperture set to narrow the field (c). Increasing time and chemical temperature (b) will darken the film
and decrease the contrast.
17. (Answer: a). The developer primarily functions to reduce, or convert, the exposed silver halide crystals
of the film emulsion to black metallic silver (a). It is the fixer that works to (b) remove and clear away
the unexposed, undeveloped silver halide crystals and harden the film to make it a permanent record.
Calcium tungstate (c) is a phosphor rarely used since 1981, when it was no longer recommended. A
latent image (d) is not produced by the developer, but by accidental ionizing radiation exposure, light,
heat, or fumes before the film has been developed.
18. (Answer: d). Only CR converts photons to metastable electrons (d). Both conventional and computed
radiography use a scintillating screen (enclosed within a cassette) (b) that emits light (a) and must be
processed in a separate unit (c).
19. (Answer: b). This study as described is incomplete because the technician fails to provide an exposure
at the 15-minute interval and hourly after 90 minutes if requested by the veterinarian (b). It should
also include an immediate exposure at 0 and 15 minutes for a complete study including the stomach
(d) and a 90-minute exposure (c) to be complete (a).
20. (Answer: a). A histogram (a) in digital radiography takes into account the frequency of appearance of
a given object characteristic. For example, extremities are imaged as high-contrast structures (little soft
tissue and much dense bone), whereas abdomens are imaged as low-contrast subjects with much soft
tissue and very little dense bone. The algorithm (b) is the formula whereby the image is produced
from the raw data of the electrical signal. Typically, this is determined within the manufacture of the
digital plate (c) and the computer interface (d).
CHAPTER 18 ZOONOSES
1. (Answer: a). Cat scratch fever is transmitted by domestic cats in normal oral flora and transmitted to
claws during grooming (a). It is therefore zoonotic, contrary to choice (d). It is bacterium and not a
rhabdovirus (b). It is not serious (c) and is usually self-resolving.
2. (Answer: b). Ancylostomiasis, or hookworm, can be acquired if larvae work their way into the skin of
a person or animal (b). For this reason, it is not a good idea to keep childrens sandboxes
uncovered (d); uncovered sandboxes invite cats and wildlife to use them as a litterbox and increases
likelihood of hookworm infection. Hookworm is not detected using interdermal tuberculin testing,
radiography, or blood culture and isolation (c), nor is it very difficult to detect (a). Instead, it is easily
diagnosed by sighting ova on fecal flotation, as well as through clinical presentation and appropriate
history.
3. (Answer: d).Leptospira is primarily transmitted by contact with infected urine, water, soil, or animals
(d) and not by fecal-oral contamination, bites from infected birds, or during molting (a, b, or c).
4. (Answer: b). Mycobacterial infection is detected using interdermal tuberculin testing, radiography,
and culture and isolation (b). It is not true that it is contracted by only a few species (d) or that it can
be controlled through childhood vaccination programs (c). Finally, it is not known to cause hepatic
dysfunction but is associated with the respiratory system, primarily causing tuberculosis (a).
5. (Answer: d). All of the statements made here (d) about the pathogen Toxocara spp. are true. It can
cause visceral larval migrans (LVM) and ocular larval migrans (OLM) in humans (a), as well as
intestinal obstruction in the host (c). The pathogen can infect most species of animals, as well as
humans (b).
6. (Answer: a). In humans, MRSA often initially manifests as a small pimple or boil (a). It is not true that
exposure always results in a pathological condition (c); instead, some individuals do not become
infected but become colonized by the bacteria. It is also not true, then, that it always results in
amputation of the infected limb (b); by contrast, the truth is that many infections can be successfully
treated with antibiotic therapy. Finally, it is not true that MRSA is difficult to transmit (d);
unfortunately, transmission can occur very easily by direct contact or environmental contamination.
7. (Answer: a). Tularemia (c) is the only disease listed here that is not transmitted by rickettsial
organisms. The othersRocky Mountain spotted fever, Lyme borreliosis, and Ehrlichia (b, c, and d)
are.
8. (Answer: c). Tapeworm infections may be transmitted by eating an infected flea (c). It is not true that
they are transmitted when the tapeworm segments break off and grow into a new, fully formed adult
or that they are always highly pathogenic (a or b). Finally, they cannot be treated with antibiotics (d);
instead they must be treated with cestode-specific anthelmintic medication such as praziquantel.
9. (Answer: a). To reduce the exposure to, and transmission of, avian Influenza type A viruses (i.e.,
subtypes H5N1, H5N2, H7N3, H7N7, H7N9), use appropriate personal protective equipment
(a)masks and hand hygiene are the best prevention. The use of cold water over heat or chemical
compounds (c) is false; in fact, the opposite is true: disinfection, heat sterilization, alcohol, 5% bleach
solution, formalin, and iodine compounds are effective disinfection methods. Long-term storage of
dead, possibly infected birds on poultry farms for future study and testing purposes (d) is not a good
idea. Instead, immediate removal and disposal of dead birds is required. Finally, of course attending
markets and farms where live poultry are housed or sold (b) is false.
10. (Answer: c). The avian species (c) are the primary reservoir for Chlamydia psittaci, not mammals or
reptiles (a, b, or d).
11. (Answer: c). Dermatophytosis (ringworm) infections are primarily acquired by contact with
contaminated skin, hair, equipment, bedding, or contaminated soil (c), not via the fecal-oral route (d).
They are not parasitic (a), but mycotic (fungal); the lesions are not black, flat, and linear (b), but red,
raised, and circular.
12. (Answer: c). Incredible as this may sound, the rhabdovirus that causes hydrophobia has an incubation
period of 9 days to 2 years or longer (c). That is because the virus migrates through the body very
slowly. If the bite is on a distal part of the body, the incubation period may be very prolonged; as long
as 8 to 9 years has been reported. It is not true that there are multiple successful treatments for this
disease (a); there is no effective, reliable treatment for rabies. Behavioral changes can begin during
stage 1, not stage 2 (b), which is characterized by progressive paralysis and death. Finally, it is not true
that there is a simple laboratory test to identify this infection (d); instead, the only tests that are
available involve tests that are run on brain tissue (hippocampus, brain stem, cerebellum).
13. (Answer: d). All of these statements are true (d) about salmonellosis transmission. It is true that
washing carriers such as reptiles and their cage items in the kitchen sink (a) increases the chance of
oral ingestion of the bacteria and subsequent infection, as does using dog chew treats made from
swine ears or snouts (b); and feeding a BARF diet to pets (c); raw meat diets have a marked increase of
salmonella ssp. contamination.
14. (Answer: d). The primary vector for the West Nile Virus is mosquitoes, primarily the Culex ssp. (d),
not the fruit bat, crocodile, or wild avian species (a, b, or c), the latter of which serve as reservoirs, but
not vectors.
15. (Answer: c). In scabies, microscopic examination of skin scraping will show mites and ova from
infected lesions (c), even though recovery of these may be difficult because of the thickened lesions.
These lesions not only thicken but also are alopecic and pruritic in both humans and animals, contrary
to (a). It is not true that animals are not pruritic, as asserted in choice (a); instead, patients can receive
prophylactic ivermectin. Finally, the mites that cause scabies are not transmitted by air (d) but by
direct contact.
16. (Answer: d). Alveolar hydatid disease manifests as jaundice, epigastric pain, and hepatomegaly (d). It
may also include malaise and hepatic cysts. It is not true that their definitive hosts are prey species (b);
instead, the prey species are intermediate hosts; predators are the definitive hosts. The proglottids are
not large (a) but rather very small. Finally, treatment in humans requires excision of the cysts, not
anthelmintic therapy (c), which is used to treat animals only.
17. (Answer: a). Swine are, it is true, susceptible to both human and avian influenza viral infections (a).
However, it is rarely fatal as in (b), and in fact many infected swine never show signs of illness.
Transmission is not primarily fecal-oral (c), but is primarily through droplet inhalation and direct
contact. Rapid flu tests (d) often show a false-negative result.
18. (Answer: b). Toxoplasmosis is caused by a single-celled microorganism (b). It is not caused by
nematodes, mites, or fungal spores (a, c, or d).
19. (Answer: a). The Yersinia spp. that causes the plague is transmitted by flea bites, inhalation of
contaminants, or direct contact with infected animals (a). It is not prevented by vaccine (b); instead,
control of rats and the fleas that live on them is the best prevention. The plague has not been virtually
eradicated (c); it is still found everywhere, worldwide. Finally, the good news is that despite its
reputation, the plague is not always fatal, as in (d). Early antibiotic therapy is very effective; however,
without treatment, mortality may occur quickly, in as early as in 5 days.
20. (Answer: d). Infectious organisms may invade outside their normally preferred host species if an
individual host is sufficiently immunocompromised (d)contrary to (a)but not always, as in (c).
Finally, choice (b) is also false; if an individuals immune system is strong, it can fight off invasion
by many types of pathogens; thus, even if an individuals immune system is compromised, that
does not necessarily mean a pathogen will invade.
CHAPTER 19 PHARMACOLOGY
1. (Answer: a). Veterinary technicians may be responsible for any aspect of medication administration
EXCEPT prescribing medication (a). Only licensed veterinarians may prescribe, diagnose, and
perform surgery. In the hospital ward, the veterinary technician is often the person calculating the
amount of drug to give (c), preparing the dosage, administering the drug (b), and observing its effects
(d).
2. (Answer: b). Extra-label drug use (ELDU), also called off-label use, means using a drug for another
purpose besides that indicated (b), and outside standard prescribing (d). This is not illegal (c) within a
valid veterinarian-client-patient relationship, except in the treatment of food-producing animals. Drug
compounding (mixing or making medications) (a) is often acceptable under the same conditions.
3. (Answer: d). The right concentration (d) is not listed in the five rights of drug administration. Instead,
the five rights of drug administration include right patient (a), right drug, right dose (b), right time (c),
and right route of administration. The correct dose of a medication could be measured from different
concentrations of that medication, so concentration (d) is not a constant. For example, a dose of 100
mg can be measured from a 100 mg/mL concentration (1 mL) and a 50 mg/mL concentration (2 mL).
4. (Answer: c). The three checks technique is used when filling prescriptions or medication orders to
ensure that the correct medication is chosen (c). Look at the label when selecting the container; read
the label while removing the medication from the container; look at the label again when returning
the container to storage. The other aspects listed here are addressed in the five rights of correct
medication administration (a, b, and d).
5. (Answer: a). Although some nematodes (a) are very small, they are not as a group categorized as
microscopic life. Antimicrobial drugs are effective only against microbes such as viruses, fungi, and
bacteria (b, c, and d).
6. (Answer: b). The full course of antimicrobial medication must be given (b) to ensure that the infection
is cleared. Symptoms of infection may improve or disappear before all of the pathogens are killed, so
symptomatic treatment is not appropriate (a). Some medications will be better tolerated or absorbed
from a full stomach (d), but this is not consistent: others require an empty stomach or a stomach free
of certain foods (such as dairy).
7. (Answer: a). Sulfa drugs disrupt microbial metabolic activity (b). Other antibacterial drugs may work
by any of several mechanisms to prevent DNA synthesis (b), interfere with cell wall formation (c), and
interfere with the microbial protein synthesis (d).
8. (Answer: a). Opioids block the pain impulse in the brain (a) and therefore reduce the perception of
pain, but they do not prevent pain signals from reaching the CNS (b) or block perception of other
stimuli. Opioids do not have an antiinflammatory (c) or anesthetic (d) effect.
9. (Answer: d). In general, corticosteroids should not be given concurrently with NSAIDs such
meloxicam (d) because of the risk for additive adverse effects. There are no specific interactions of
concern between prednisone and midazolam, diphenhydramine, or famotidine (a, b, and c).
10. (Answer: d). Doxapram (d) stimulates the respiratory center in the brain. Dopamine and dobutamine
(a and b) are adrenergics, and dexmedetomidine (c) is an alpha-2 agonist.
11. (Answer: a). In animals, problem behaviors that can be observed (a) can be addressed. Internal states
such as bipolar disorder (b) and attention deficit hyperactivity disorder (d) would have to manifest in
particular behaviors to be recognized and addressed with medications and behavior modification
training. Chronic pain (c) is generally treated with analgesic medications and other pain-relieving
modalities.
12. (Answer: a). Antiarrhythmics are given to patients with cardiac arrhythmia in an attempt to
reestablish a normal pattern of electrical conduction within the heart muscle (a). They do not act on
nerve impulses in the brain, intestines, or skeletal muscles (b, c, and d).
13. (Answer: b). Epinephrine (b) is an adrenergic drug with direct stimulatory effect on the heart,
increasing rate and contractility. Atropine (a) is an anticholinergic drug with an indirect effect on heart
rate. Methylprednisolone (c) is a steroidal antiinflammatory drug. Sodium bicarbonate is an
alkalinizing agent (d).
14. (Answer: b). Chlorpromazine (b) is a phenothiazine drug with antiemetic properties. Ranitidine (a) is
a histamine-2 receptor antagonist used to reduce gastric acidity. Morphine (c) is an opioid
analgesicit can actually cause nausea and vomiting. Amlodipine (d) is a calcium channel blocker
used to treat hypertension.
15. (Answer: d). Narcotics (opiates) inhibit or reduce GI motility (d). Hyperosmotics and stimulants (b
and c) are used to treat constipation and can cause diarrhea. GI side effects of NSAIDs (a) can include
anorexia, vomiting, ulceration, and diarrhea.
16. (Answer: d). Hypothyroid patients usually require supplementation with levothyroxine (T ) (d) and
4
sometimes liothyronine (T ). Methimazole, radioactive iodine, and thyroidectomy (a, b, and c) are
3
2. (Answer: a). It is accurate that 6 mm = 0.006 m (choice [a]). Calculate: Move the decimal place to
the left 3 spaces.
3. (Answer: c). Take 1000 mL of 45% solution and add 2 L of sterile diluent (c).
4. (Answer: d). All three responses are appropriate (d). There must be a veterinarian-client relationship
to dispense any type of prescription drugs (a and b). The veterinarian must examine the patient before
dispensing any drugs (b). Finally, the veterinary technician cannot prescribe drugs, and these require
a prescription (a and c).
5. (Answer: a). The approximate drip rate is 10.3/10 seconds (choice [a]).
6. (Answer: d). To make 500 mL of 50% solution, take 250 mL of pure solution and add 250 mL of sterile
water.
7. (Answer: a). The final concentration is 25 mg/mL with a percentage of 2.5%.
8. (Answer: a). If 30 mL of solution is added to 70 mL of water, the final solution (v/v) is 30%.
9. (Answer: c). Give 2 tablets for 1 dose, and 4 tablets are needed over a 24-hour period. 20 kg 5
mg/kg = 100 mg. The dose is twice per day for 10 days. The tablet size is 50 mg therefore 100 mg/50
mg = 2 tablets per dose and 4 per 24-hour period
10. (Answer: c). To prepare 1.5 L of a 1:200 (w/v) solution given a 12% solution and sterile water, take 62.5
mL of the 12% solution and add 1437.5 mL of sterile water.
11. (Answer: a). Premix 1 mL/10 kg = x/26 kg = 2.6 mL. Propofol dose range 1 mL /4 kg = x
mL/26 kg = 6.5 mL and 1 mL/5 kg x mL/26 kg = 5.4 mL. Atropine dose range (26 kg
0.02)/0.5 = 1.04 mL and 26 kg 0.04 / 0.5 = 2.08 mL.
12. (Answer: b). (0.3 10 )/100 = 3000 ppm.
6
19. (Answer: a). Give 3 drops (gtt) in left eye (OS) every (q) 4 hours for 3 days. Then as needed (prn). No
Repeats (NR). Prescription labels should be very specific, with no ambiguity. The name of the patient
should be noted, as well as how much of the drug and how to administer it. The length of the
administration of the drug should also be noted on the label.
20. (Answer: d). Convert 80 mg to grams = 0.080 g
For a vial that contains 80 mg of drug in 2 mL of injection, 0.5 mL of the injection should be
administered to obtain 0.02 g of drug.
CHAPTER 21 ANESTHESIA
1. (Answer: c). Preanesthetic drugs are not used to stimulate respiratory rate (c). Instead, they provide
mild sedation (b) and analgesia (a) for preoperative, intraoperative, and postoperative phases and
reduce anxiety (d), calming the patient.
2. (Answer: c). Neuroleptanalgesic (a) is a combination of a tranquilizer and/or sedative with an opioid
(analgesia). Anticholinergics (d) are parasympatholytic drugs that exert their effects by blocking the
actions of the parasympathetic neurotransmitter acetylcholine at the muscarinic receptors.
Cyclohexamine (a) is a specific classification of anesthetic called dissociative drugs that interrupt
neural transmission that induce unconscious and conscious brain functions. Barbiturates (b) are based
on the chemical substitutions on the barbituric acid molecule and the duration of action.
3. (Answer: b). Tranquilizers (b) can calm anxieties without altering consciousness. Anticholinergics (a)
are parasympatholytic drugs used to prevent or treat bradycardia. A sedative (c) is a tempting choice,
but it reduces excitement or irritability by causing decreased activity. Finally, isoflurane (d) is an
inhalant anesthetic agent used to produce unconsciousness and general anesthesia.
4. (Answer: d). Atipamezole is an alpha-2 antagonist that is specific to dexmedetomidine (d), which is
its opposite, an alpha-2 agonist. Ketamine (a) is a dissociative anesthetic drug; butorphanol (b) can
reverse the effects of morphine. Finally, acepromazine (c) is a tranquilizer that can be used in
combination with ketamine to reduce seizures in dogs.
5. (Answer: c). Pure mu agonists include morphine (a), meperidine (b), hydromorphone (d), and
fentanyl, which stimulate all opioid receptors. By contrast, butorphanol (c) is an agonist-antagonist
opioid.
6. (Answer: b). Only the 2-year-old St. Bernard with the hernia should be put on this drug (b).
Anticholinergics are contraindicated in patients undergoing upper GI barium series and endoscopy
(d); any patient with tachycardia (c) or ventricular arrhythmias; and geriatric patients with organ
dysfunction (a).
7. (Answer: c). Morphine and meperidine (a and b) have been reported to cause histamine release when
administered intravenously.
8. (Answer: b). Delirium or excitement occurs in stage 2 (b). Effects of each stage are as follows:
Stage 1: induction stage, stage of analgesia, and altered consciousness
Stage 2: stage of delirium or excitement, loss of consciousness
Stage 3: stage of surgical anesthesia
Stage 4: stage of medullary paralysis (apnea and cardiac arrest)
9. (Answer: c). Thiopental (c) is the only extremely alkalinic solution. If tissue sloughing accidentally
occurs, dilute the perivascular thiopental by injecting small amounts of normal saline around the site.
The other drugs are not associated with tissue necrosis. For example, dexmedetomines (a) side
effects include cardiovascular effects; pentobarbitals description (b) specifically notes that it can
be administered IM for sedation without tissue reaction. Finally, methohexital (d) is associated with
profound respiratory depression.
10. (Answer: a). Propofol (a) is a short-acting hypnotic and alkylphenol derivative. It is rapid acting with
smooth, excitement-free inductions, rapid smooth recovery as a result of the redistribution, and rapid
metabolism (redistribution to vessel-rich areas such as brain rather than muscle or fat). Diazepam (b)
is a member of the benzodiazepine family, which act as muscle relaxants and anticonvulsants, and are
classified as tranquilizers (mild calming effect). They are additives or synergistics that are used with
other drugs. Ketamine (c) is a cyclohexamine with selective analgesic properties, used in conjunction
with benzodiazepines for induction, but not used alone. Thiopental (d) is commonly used as an
induction agent, but it is not used for maintenance anesthesia because of the protein binding and lipid
solubility effects.
11. (Answer: b). The diameter-indexed safety system (DISS) (b) is a set of connectors that are specific to
each gas. The flow meter (c) measures and indicates flow of gases into the vaporizer and then to the
patient, and the check valve (a) located in the E tank yoke, anesthetic machine pipelines, and
regulators, ensures a one-way safe flow of gases from the regulator, tank, and/or pipeline. Finally, the
pressure relief valve (d) is also known as the pop-off valve and does just what its name implies. It is
located on the circle systems carbon dioxide absorber or Bain system mount.
12. (Answer: d). The oxygen flush valve can actually create increased pressure within the breathing
system when connected to the patient, not relieve pressure (d). In an oxygen flush valve, oxygen
bypasses the vaporizer (a), delivering 100% oxygen to the breathing system (b). Besides flushing the
system with pure oxygen, it also can fill the reservoir bag and system (c) to check for leaks.
13. (Answer: d). All three methods (d) are effective measures for reducing waste anesthetic gas exposure
in the environment. For example, directly attaching a scavenger hose (a) to an active scavenging
system will ensure there are no waste gas anesthetics going directly into the room or atmosphere.
Leak-testing an anesthetic machine (b) will identify any significant leaks, which could lead to waste
gas exposure. Finally, annual preventive maintenance (c) will ensure that the anesthetic machine is
functioning properly per the guidelines and recommendations set by the manufacturer. Preventive
maintenance will also ensure the safety of the patient and personnel.
14. (Answer: b). Halogenated anesthetic agents (i.e., isoflurane, enflurane) should not exceed 2 parts per
million (ppm) dose per day (b). It is acceptable to exceed 1 ppm (a), as long as 2 ppm is not exceeded,
which is recommended by Occupational Health and Safety Administration (OHSA). Finally, 3 ppm
and 4 ppm (c and d) would exceed OSHAs recommended daily exposure.
15. (Answer: b). In this list, only the analgesic (c) has the ability to significantly affect both vital
physiological signs and pathological effects. Antisialogogic drugs (d) prevent salivation. Antitussive
(a) agents suppress the cough reflex. Agonists (c) have an affinity for a specific receptor before they
produce an effect.
16. (Answer: c). NSAIDs. [c] Barbiturates, local anesthetics and Alpha2 agonists do not work peripherally
by reducing prostaglandins production on area of damaged tissue. Barbiturates (a) cause CNS
depression by acting on CNS neurons and GABA receptors. Local anesthetics (b) block sensory and
motor nerves and nerve transmission and Alpha2-agonists (d) stimulate alpha-adrenoreceptors
causing CNS depression and decreased catecholamine release.
17. (Answer: b). The only acceptable rate for ventilation during IVVP is 8 to 12 breaths per minute (b). All
other rates (a, c, and d) are incompatible with safe and ideal ventilation. The inspiration-to-expiration
ratio should be 1:2, with a tidal volume of 15 to 20 mL/kg (30 mL/kg for open chest), and an
inspiratory pressure of 12 to 20 cm H O (30 cm H O with open chest). The goal of using these
2 2
parameters is to decrease carbon dioxide levels to slightly below normal, thereby eliminating
spontaneous breathing and allowing control of ventilation.
18. (Answer: c). Capnography (c) is a graphic measurement of instantaneous carbon dioxide level of
respiratory gases and displayed as a waveform on a monitor. Electrocardiography (b) measures the
quality, rhythm, and rate of the heart. A Doppler (a) unit is a noninvasive blood pressure monitor that
also allows an audible heart rate sound and is especially useful for systolic pressure readings. Pulse
oximetry (d) measures the percent saturation of oxygen.
19. (Answer: c). A 35-kg dog requires at the minimum a 3-L reservoir bag and 10-mm or larger
endotracheal tube, eliminating choices (a) and (d). This could make it tempting to select choice (b).
However, the universal F circuit cannot be used with an endotracheal tube bigger than 9.5 mm
because the inner tube is not big enough to accommodate the larger endotracheal tube size. This may
result in hypoventilation. The correct choice, then, is (c).
20. (Answer: b). Respiratory acidosis is an acid-base disturbance in which the blood gas analysis reveals
carbon dioxide production is greater than carbon dioxide excretion (b). The increased carbon dioxide
causes a gain in acids and decrease in pH. By contrast, respiratory alkalosis is defined as carbon
dioxide excretion greater than carbon dioxide production (d), which causes excess loss of H ions (c)
+
(a) Colloids are used for edema only. (a) and (b) Colloids do not increase the protein in the blood nor
decrease interstitial blood volume.
14. (Answer: c). All these symptoms indicate moderate, or 8%, dehydration (c). Severe dehydration of 10%
or greater (d) would show more severe forms of these same symptoms, including altered state of
consciousness. The text does not discuss 3% dehydration (a), but 5% alone (b) is mild, involving
minimal loss of skin turgor and semidry mucous membranes.
15. (Answer: a). The amount of Normsol R replacement fluids for a 36.5-kg dog who is estimated to be 8%
dehydrated would be 2920 mL (a).
16. (Answer: a) PVCs can occur at any rate but pose a greater danger when occurring with a sustained
tachycardic heart rate (a). (b) PR interval represents the beginning of atrial depolarization into
ventricular depolarization. (c) Third degree heart block is also known as a complete heart block; the
most severe heart block. (d) The cells of the heart are electrically linked; therefore the depolarization
spreads quickly from the sinoatrial node to the atria in a caudal direction toward the ventricles, finally
reaching the atrioventricular (AV) node.
17. (Answer: b). Rose-Bengal stain can be used to stain devitalized tissue and to diagnose
keratoconjunctivitis sicca (KCS) (or dry eye) (b). The stain for corneal abrasions (a) is fluorescein stain.
There is no diagnostic test for vitamin deficiencies (c) other than serology testing. Finally,
conjunctivitis (d) is usually diagnosed after a complete examination of the eye.
18. (Answer: a). Gonioscopy can be used for the diagnosis of glaucoma by magnifying the lens to examine
the iris angle and anterior chamber (a). It is not used to examine either the esophagus (b) or trachea
(d), and it cannot help in the detection of KCS (c).
19. (Answer: c). Ringworm is caused by a fungus, such as Microsporum canis and Trichophyton spp (b).
Malassezia pachydermatis (c) is also a fungus, but it does not cause ringworm. Staphylococcus spp.,
Streptococcus spp., Pasteurella spp., and Pseudomonas spp. (a) are bacteria, not fungi; and Otodectes
cynotis (d) is a parasite.
20. (Answer: d). A wound is considered infected if the patient is presented for treatment more than 48
hours post injury. (a) A contaminated wound does elicit a response. (b). A surgical wound is
considered contaminated by suture material. (c) Not only microorganisms can contaminate a wound.
All wounds are contaminated; however, a contaminated wound elicits no immune response from the
host body.
is saturated with oxygen (d). It does not identify the amount of total hemoglobin (b), but the
percentage available that is saturated; nor does it tell you the amount of oxygen (a), but the
percentage of hemoglobin that is saturated with oxygen. Pulse oximetry is not a measure of carbon
dioxide expiration (c).
9. (Answer: b). Cardiogenic shock (b) is poor tissue perfusion as a result of decreased forward blood
flow from the heart. This can be confused with hypovolemic shock (a), in which the poor tissue
perfusion is a result of low blood volume, frequently seen as a result of trauma. Septic shock (d) is
caused by the presence of toxins in the blood or other tissues; and anaphylactic shock (c) is is caused
by a hypersensitivity to an allergen.
10. (Answer: d). 100-150 ml/kg/min (correct answer). (a) 2-3 L/min (flow rate for flow by oxygen). (b) 2-5
L/min (flow rate for oxygen hood, mask or cage). (c) 40 ml/kg/min (flow rate for oxygen delivery via
an endotracheal tube).
11. (Answer: c). In head trauma, place the patient on flat board and elevate the board to approximately 30
degrees (c) in an attempt to decrease intracranial pressure. A 5% to 10% elevation is not enough (a and
b), and 75% is too high (d).
12. (Answer: a). Hypercalcemia is a medical emergency because of its effects on the kidney (a). The heart
(d) may seem like a strong choice, except that it is more affected by calcium administration, which can
cause arrhythmias or bradycardia. Hypercalcemia has no known effects on the spleen or liver (b or c).
13. (Answer: d). Gastric dilation (a) is characterized by abdominal distention; nonproductive retching;
and pale, muddy, or gray mucous membrane. The nonproductive retching and gray mucous
membrane are the biggest tip-offs herethey are not associated with intussusception, GI obstruction,
or peritonitis (a, b, or c).
14. (Answer: c). Calcium gluconate (c) is helpful in treating eclampsia. Atropine (b) is used to increase
heart rate, among other things; epinephrine (c) is used to increase heart rate; and dexamethasone (a) is
a steroid used to decrease inflammation, among other things.
15. (Answer: a). To treat hypoglycemia, supplement diet with a dextrose bolus diluted (a) 1:4 with a
crystalloid. This will help prevent phlebitis. The bolus should not be given undiluted (b). The SQ route
(c) is irritating to the skin because dextrose is hypertonic; the IM route (d) is equally undesirable
because the hypertonicity irritates the muscle as well.
16. (Answer: c). 2 hours is the correct amount of time between fetuses. hour and 1 hour is too short a
period of time (a and b) and (d) 4 hours is too long a period of time.
17. (Answer: d). Clinical signs of acetaminophen toxicosis show up 1 to 2 hours after ingestion and
include brown or cyanotic mucous membranes (d). Membranes that are pale (a) are associated with
hypovolemia; yellow mucous membranes (b), with liver conditions; and brick red (c) mucous
membranes, with septic shock.
18. (Answer: a). Normal values of urine output should be 1 to 2 mL/kg/hr. l to 2 mL/hr and 2 to 3 mL/hr
would both be too little (b and c). 2 to 3 mL/kg/hr (d) is more than required.
19. (Answer: c). An animal that is choking (patient 3) should be seen first (making choice [c] the only
correct answer). Establishing a clear airway and adequate respiration is always the first priority.
Second, the dehydrated animal (patient 2), especially an older one, should be seen second; it
represents an urgent situation, but not as urgent as choking. Third, respond to the animal with a fish
hook in its lip (patient 4), which has the potential to cause a further injury. All three should be seen
before a stable patient with a small laceration (patient 1).
20. (Answer: c). Respiratory distress (patient 3) should always be tended first. Dehydration and 3 days of
vomiting and bloody diarrhea (patient 2) should be seen next, especially in so small an animal. The
animal just hit by a car (patient 1) should be seen next. Pink mucous membrane and no obvious
distress means the patient can wait while the two more emergent cases of respiratory distress and
severe fluid losses are seen first. However, because patient 1s injuries from the car accident are
still fresh, the patient needs to be assessed for as-yet-undetected internal injuries, which may be
serious. The small, visible laceration (patient 4) can, in this case, go last.