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Datasheet of Stat5 Inhibitor

Description:.
Stat5 Inhibitor is a cell permeable nonpetidic nicotinoyl hydrazone which suppresses Stat5 via binding to the SH2 domain.
Studies indicate that Stat5 Inhibitor suppresses the SH2 domain of Stat1 and Stat3 to a lesser extent than Stat5 inhibition. In
addition, Stat5/Stat5 DNA binding in K562 nuclear extracts are inhibited by Stat5 Inhibitor. Stat5 functions biologically in
various processes such as homeostasis of hematopoietic stem cells, development of blood cells, growth hormone effects, and
differentiation of mammary epithelium.

Chemical Information

Catalog DC10139

Purity of current batch: >98%

293.28
Molecular Weight (MW)

Molecular Formula C16H11N3O3

CAS No. 285986-31-4

Solubility (25C) DMSO

Storage Store at -20C (desiccating conditions).

Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in
advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable
for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room
temperature for at least 1 hour.