Datasheet of SBI0206965

Detailed information:
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USD250.0/50.0mg;
Price USD400.0/100.0mg
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Product Name SBI0206965

2-((5-bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-
Chemical Name
methylbenzamide

Synonyms SBI0206965;SBI-0206965;SBI 0206965

CAS No. 1884220-36-3 Catalog No 17011610

Br
Molecular Weight 489.33 O
HN O N O
Molecular Formula C21H21BrN4O5 N
HN O

Other information N/A O

Items Specifications Results

Appearance Off-white solid Complies

HNMR 400MHz,d6-DMSO Complies

Analysis
HPLC 98.0% Complies

Storage condition Kept under dry and cool condition

The above substance has been tested according to In house Standards, and it
Conclusion
meets requirements.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com
 SBI-0206965 is a highly selective ULK1 kinase inhibitor in vitro and suppressed
ULK1-mediated phosphorylation events in cells, regulating autophagy and cell
survival. SBI-0206965 greatly synergized with mechanistic target of rapamycin
Description (mTOR) inhibitors to kill tumor cells, providing a strong rationale for their combined
use in the clinic.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com