New QU 8/2017

1- narcotic iv still effective till :-

a- 12 hours b- 24 hours
c- 36 hours d- 72 hours

2- women with phobia with car which drug is for ttt:

Buspirone (Generalized Anxiety Disorder GAD)

3- Flumazenil with overdose of diazepam with no effect due

to -received multiple anesthetic agents in addition to benzodiazepines or
- antidote was small amount or - antidote taken after 4 hrs

4- Most potent Statin: Rosuvastatin, Pitavastatin and

Atorvastatin

5- which has fastest action diazepam or lorazepam: Lorazepa

6- 48 yrs man he took pneumococcal with influenza

vaccines, which vaccine should take next
a- influenza b- pneumococcal polysaccharide
c- hepatitis B d- MMR

7- Lithium and Gentamicin can be measured and curved

down after:
Therapeutic Drug Monitoring (TDM)

8- GMP in KSA means: good manufacturing practices

9- Simvastatin max dose in geriatric:

a- 20 mg c- 40mg
d- 60 mg e- 80 mg

10- Monophasic OCs means :

a-Estrogen b-progestron
c-Estrogen + progestrond
11- Warfarin antidepressant drug interactions :
a- Decrease Warfarin metabolism b- increase plasma level

12- Athlete's foot player treatment:

Antifungal such as Terbinafine (Lamisil); 250 mg/day orally once
or 2 divided doses for 2-6 weeks

13- Carbidopa and Levodopa contains mainly effect ?

Entacapone which is selectively and reversibly inhibit COMT

14- Potassium channel blockers:

class III antiarrythmia

15- Interleukin I Inhibitor : Anakinra

16- Ciprofloxacin side effects: seizures
17- Cephalosporins side effects : Allergic reactions (cross-
sensitivity) &Hypoprothrombinemia & Mild stomach cramps

18- Cyclophosphamide side effects:

Bladder toxicity (Hemorrhagic_Cystitis)

19- Intermittent cough (asthma) treated with:

Short-acting 2-adrenoceptor Agonists (SABA)

20- Toxin that can be used therapeutically:

a-Botulinum toxin b- x toxin

21- 2 Vaccines (live attenuated and killed ) how can be

administered :
a- at same time b- day after day
c- 2 weaks between them d- monthes between them
22- Phase 3 and phase 4 in cardiac action potential
Phase 3 (Rapid Repolarization K )
Phase 4 (Resting Membrane Potential; RMP)

23- Tyramine not taken with :

Monoamine Oxidase Inhibitors (MAOIs)

24- According to KSA cold preparation; drugs not given

to children less than:
a-2 years b-4 years
c-6 years d-6 years

25- Daily dose of ibuprofen:

a-800 b-1000
c-1200 d-2000
e-3000
** If Q: Maximum dose of Ibuprofen : 3200

26- ttt of hyperkalemia

a- kaylexate b- Na
27- Dose of heparin: 80-100 units /kg

28- Digoxin dose calc should be measure through or post

dose ????
-Trough dose , before second dose by half hour
-Therapeutic Drug Monitoring (TDM)

29- types of errors in pharmacy:

a-adminstratin b-dispensing c-ommission

30- Heparin Side effect :

bleeding complicatins & Hyper sensitivity reactions & Thrombocytopenia&
Osteoporosis has been observed in patients on long-term therapy

31- Patient burn hand when cooking:

a-wash with water for 20-30 min b- put ice c-put vasline

32- SE of Lithium:
headache, dry mouth, polydipsia, polyuria, polyphagia
may include ataxia, slurred speech, coarse tremors, confusion, and convulsions,
arrhythmia, hypotention & Teratogenicity with pregnant
33- Nurse give pt dose 2 hrs later what is the type of
error: wrong time errors

34- Fingolimod which used for multiple scelerosis

must check up of the following: ECG

35- Patient with depression and took amitriptine after

days she felt depreesed Dr should:
a-shift b-double dose
c- add another antidepressant

36- Old patient end stage colorectal cancer take 60 mg

morphine twice . Suffer pain when he go to bathroom. Add
?:
a-Mg b- morphine c-..

37 Patient second exposure in h. Pylori and there is risk

of resistance he took in first time:
a- amoxicillin + clarithromycin + lanzopazol with doses
b- amoxicillin + bithmuth sulfate + clarithromycin+ amoxicillin
c- Bithmuth sulfate + doxycycline + lanzoprazole
d- Bithmus sulfate+ tetracycline + lanzoprazol

38- Phenytoin suspension dose : 15ml/day or 5 mL (125 mg/5 mL) three times
daily, or one teaspoonful, by mouth 3 times daily. Adjust the dosage to suit
individual requirements, up to a maximum of 25 mL daily
39- Penicillin allergy caused by : IgE

40- according to the saudia food and drug authority cough

medications are contraindicated in children:
A- less than one year B- less than two years
C- less than three years D- less than six years

41- at what age the tuberculosis vaccines (BCG) should be

given:
a- at birth b- 6weeks_2months_4months
c- 2months_4monthd_6months d- 1 year

42-a man travelled to Africa and while he was there he got

ameoba and started metronidazole 500mg three times daily
after 7 days he still have symptoms .what medication can
be added ?
a- vancomycin b- erythromycin
c- diloxanide

43- a child is taking high dose amoxicillin (99mg/kg) for

otitis media came to the clinic for pneumonia and infuenza
vaccine:
a) cancel the vaccines b) proceed to give the vaccines
c) delay the vaccines for one year

44- MMR vaccine is given at what age?

first dose 12months and second dose 4years

45- the cause of diphtheria: corynebacteriam

46- Vit c used for:
a-Coloring agent b-Preservative
c-Tasting agent
47- Alndronate dose per week: 70mg once aweak =10 mg daily
48- Antidot for atropin? : Physostigmine
49- Role of scientific office in pharmaceutical company:
A pharmaceutical establishment that provides scientific, technical and
marketing information on pharmaceutical preparations throughout the
Kingdom.

50- Nilotinib:
Tyrosine Kinase Inhibitor use as
chronic myelogenous leukemia (CML)
gastrointestinal stromal tumors (GISTs)

51- 40 years .playing sport . Dry cough , Weezing ,

chest tightness :
a- Laba b- SABA c- Inhaled corticosteroid d-Loncet

52- Dr ask pharmacist about interaction between warfarin

and heparin? Chosse ipnr after how many days and the
test result:

53- Prescription of tramadol written 2days ago in Riyad

and you are a pharmacist in dammam what will you do
a- don't dispense b- call doctor
c- dispense
d- calculate the missing days and dispense all

54- Mechanism of action of sitagliptin:

dipeptyl peptidase no. 4 inhibitor (DPP IV Inhibitor)

55- adanafil effect on pt using nitrate with diabetes

is: non pharmacological treatment
56- most common dispensed in otc : Multi Vitamins

57- drug disponsed to patient and the nurse found that

there was another dose at the patient room so what
should she do :
a- return the dose to the pharmacy
b- keep it to the next dose
c- throw it away

58- one of the OTC : Ibuprofen

59- Misoprostol is used for :

a- prevent ulcer b- prevent and treat gastric ulcer
c- treatment of ulcer

60- A woman with seizure is on valproic acid shes

planning to get pregnant what is the best choice?
a- continue on valproic acid b- stop valproic acid
c- change to levetiracetam

61- which of these laxatives have the lowest onset of

action:
a- milk of magnesia b- glycerin
c- Biscodyl d- psyllium

62- A patient with a gastric ulcer caused by h.pylori

and started on triple therapy ( clarithromy,
metronidazole ,ppi)but his symptoms not improved
because of bacterial resistant :
a- (clarithromycin, amoxicillin,ppi)
b- (bismuth, tetracycline, metronidazole ,ppi)
c- (bismuth, doxycycline, metronidazole,ppi)
63- at what time 99% of the drug will be cleared from
the plasma:
a- 4.5 t half b- 6.6 t half
c- 7.4 t half

64- What is the meaning of pregnancy category B :

Animal reproduction studies have failed to demonstrate a risk to the fetus
and there are no adequate and well-controlled studies in pregnant women.

65- validity of Pharmacy permit :

a-1 year b-3 years
c-5 years d-10

66- MMR vaccine is given at what age :

first dose 12months and second dose 4years

67- when we should stop plavix before cardiac surgery

:
5-7 Days

68- in which muscle we give vaccine for infants :

The vastus lateralis muscle in the anterolateral thigh
69- -which of this lowest potency laxative :
a- glycrine b- magnesium milk
c- bisacodyl

70-Pharmacy regulation & guidlines is comming from:

a-MOH b-SPA
c-sFda d-scfhs

70-therapeutic equivalent dose of omeprazole 20 is:

a- cimetidin 800 mg b- esomeprazole 40 mg
c- ranitidine 300 mg d- pantaprazole 40 mg

71-dose of ferrous sulfate: 300 B.I.D

72- which NSAID has more enterogenic effect

a- Piroxicam b- Naproxen c- Dicofenac d- Ibuprofen
73- physician prescribe Amoxicillin if you don't have the
brand what you will do:
a- Will you give the generic b- send him an other pharmacy
c- tell him you dont have the medicine

74- child receive high dose Amoxicillin for otitis and he

has-appointment for vaccine what we do shall we postponed
the vaccination ?: NO
75- child receive short acting b agonist without
improvement then he develop cough with wheeping what is
the treatment: a- Amoxicillin b- azithromycin
c- steroid

76- pt was treated with Floxeten without improvement after

how many weeks: you shift him to anther group
77- Warfarin and heparin was prescribed to pt in hospital
how long he will take the heparin and how much the INR :
Take heparin for 2 days with warfarin then stop heparin , warfarin biological t/2
after 48 hours

78- Total knee replacement which anticoagulation he should

continue:
a- asprin b- Clopidogril

79- Pseudoefedrine is:

a- antiallergic b- decongestant

80-20 mg omeprazol equal to which doses of pantoprazol or

ranitidin in the H.Pylori treatment: pantaprazole 40 mg
81- Pt with Prostate hyperplasia and dysuria what
medication u will give :

82-35years BMI35 , (Oral contaceptive)?:

Only progesterone pill

83- Baby with immunedeficiency syndrome took

immunoglobulin which vaccines is C.I:
a- mmr b- rubella c- meningitis d- rotavirus (RV)

84- Baby with fever & tugging ear. Doctor exclude

bacterial infection : (amoxicillin with different doses + antiviral i do not
remember)

85- Calculate cr.cl age 40 &weight 80 &sr.cr=0.5 Result mg

/ml
- For male
- For female = CrCl of male x 0.85

86- what is the treatment of keto acidosis :

-Correction of fluid loss with intravenous fluids

-Correction of hyperglycemia with insulin

-Correction of electrolyte disturbances, particularly potassium loss

-Correction of acid-base balance

-Treatment of concurrent infection, if present

87- what should be monitored when giving patient lithium

therapy:

88- Liraglutide MOA:

Liraglutide (NN2211) is a derivative of human incretin (metabolic hormone) glucagon-like
peptide-1 (GLP-1) that is used as a long-acting glucagon-like peptide-1 receptor agonist,
binding to the same receptors as does the endogenous metabolic hormone GLP-1 that
stimulates insulin secretion.
89- child weight 16 kg and length 92 cm calculate the body
surface area ?

so BSA(m)= SQRT (92x16)/3600

= SQRT (.48555)

=.69681 m

90- Anti metabolite cause bone marrow suppression:

Azathioprine or Methotrexate

91- Relation between autism and vaccine:

Relation between autism and MMR vaccine ?? No relation
Relation between autism and thimerosal vaccine ?? relation
91- Urine incontinence drugs for urge conditions?:
-Anticholinergic medications
-Mirabegron (Myrbetriq)
-Onabotulinumtoxin type A (Botox)
92- Body mass index and body surface area calculation:

93- Duration of using domperidon 68 hrs

94- Duration of esomeprazole in gastroesophagial disease:

up to 24 hrs
95- Drug and dose of Infant with mild fever:
paracetamol 1 gm per day
96- Antibiotic cause hyperkalemia:
trimethoprim - sulfamethoxazole
97- Selective estrogen modulator:
tamoxifen

98- Masking acidic taste of syrup use which flavor:

strong base anionexchange resins
(grape, maple, raspberry, and wild cherry- Menthol )

99- Dose of enxaparine in male with DVT1.5 or1 rout IV or

IM:
IV
100- organophosphorus toxicity removed by: Gastric lavage

101- Reduce gastric side effect of metoformine administer

metoformine. .......?:
biggest complaint people have about Metformin is that it causes gas and
diarrhea. This can often be reduced by increasing the dose gradually

102- Dispense a prescription of diazepam for:

a- 7days b- 14 days c- 30 days

103-A man with hypertension and myocardial infarction his

medications are metoprolol and nitroglycerin for his MI he
present to the clinic with erectile dysfunction what
medication is the most appropriate for his erectile
dysfunction:
a- sildenafil b- avanafil c- no pharmacological treatment
104- Antiarrhythmic drug cause iodine hypothyroidism :
amiodarone

105- Metformin avoiding its side effect of N, V:

Metformin nausea and vomiting may be asign of lactic acidosis.And treatment is :
treating Lactic acidosis sometimes represents a medical emergency. Increasing
oxygen to the tissues and giving IV fluids are often used to reduce lactic acid
levels. Electrolyte-replacement sports drinks such as Gatorade help with
hydration, but water is usually best.

106- Pt taking prazocin , want to give him tadalafil ,

want the time duration bet them: 4 hours

107- patient is on Omeprazole and it's expired what you

advice her?:
a- she can take it if it was stored properly
b- buy a new one

108- Anti hypertension drug safe in pregnant?: labetalol

119- pt take morphen and we want replace by Fentanyl ?:
Fentanyl is 50 to 100 times more potent than morphine (80)

120- Removing a drug from formulary:

pharmacy therapeutic committee
121- Anti hypertensive drug... can affect fetal growth:
a- Amlodipine b- hydrochlorothiazide c- lisinopril
122- Diuretic side effects are ototoxicity and deafness:
a- frusemide b- triamterene c- hydrochlorothiazide

123- Food that should be avoided when taking amiodarone:

grape fruit

124- The meaning of compassionate drug use:

use a drug that not approved yet (new unapproved drug)

125- Overlapping of clexane with warfarin:

At least 5 days

126- Voriconazole dose is adjusted in hepatic impairment:

100 mg/ twice daily

127- Chlild e otitis media e QT prolongation , which abx

is CI:
azithromycin