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The Test includes 50 MCQs and time allotted is 60 minutes

Mark the answer on answer sheet. Do not write on the question sheet.

1. Viruses cannot parasitize ________

a) Bacteria b) Fungi
c) Mammals d) None of these

2. Some viruses have a calculated replication time of _______

a) 70 seconds b) 1 min. 10 sec.

c) 1 minute d) Both a and b

3. Viruses cannot _________

a) Undergo genetic recombination b) Show irritability

c) Undergo mutations d) None of these

4. When Tobacco mosaic virus infects a tobacco plant, the plant leaves become

a) Wrinkled b) Mottled

c) Both a and b d) None of these

5. First isolation and demonstration of a non-bacterial entity i.e. virus was done by ______

a) Iwanowsky b) W.M. Stanley

c) Louis Pasteur d) Robert Koch

6. Mode of transmission of Foot and Mouth disease is by ______

a) Blisters on the healthy cattle b) Blisters on the diseased cattle

c) Blisters on the foot and mouth of dogs d) No known mode of transmission

7. Under electron microscope TMV crystals are seen as _____

a) silvery crystals b) rod shaped structures

c) nucleoproteins d) All of these

8. Tobacco mosaic virus is placed under the category of _____ viruses on the basis of morphology.

a) Spherical shaped b) Tadpole shaped

c) Rod Shaped d) TMV is not yet classified

9. Polio and Measles are _____ viruses.

a) D.N.A b) R.N.A

c) Both D.N.A and R.N.A d) None of these

10. A virus infected a bacterium and caused disease in it. It is named X by scientists. X can have a
maximum length of _____ nanometers.

a) 24 b) 200

c) 100 d) None of these

11. ______ is/are involved in the attachment of the phage to the bacterial cell.

a) Base plate b) Tail fibers

c) Both a and b d) None of these

12. Capsid of HIV is of ______ shape

a) Roughly spherical b) Bullet Shaped

c) Spiky d) HIV Capsid exists in all these shapes

13. CAEV is a virus which causes AIDS in ______

a) Dogs b) Sheep

c) Human Babies d) Goats

14. Almost all organisms, including most viruses, store their genetic material on long strands of _____

a) RNA b) DNA

c) Proteins d) None of these

15. For attacking a cell, viruses prefer those cells which are ______

a) Actively dividing b) Young

c) Both a and b d) Mature and less immune

16. Glycoproteins HA and Sialidase play a crucial role in the infection of the _____ cells of the upper
respiratory tract.

a) Epithelial b) Digestive

c) Respiratory d) Nerve
17. During a lytic cycle in the attack of a bacteriophage on a bacterium, the bacterial cells rupture
because _________

a) Viral phages are toxic b) Viral phages exert pressure on the cell wall of bacteria

c) Nucleus of phage is taking d) None of these

control of bacterium

18. __________ are capable of multiplying inside of living cells.

a) Bacteria b) Fungi

c) Cloning vectors d) All of these

19. _____ on the surface of the virus particle help viral envelope attach cell membrane in HIV.

a) Lipoprotein covers b) Spikes

c) Tail fibers d) Base plate

20. Earliest symptoms of HIV occur between ________

a) 6 weeks and 12 weeks b) 6 weeks and 3 months

c) 1 month 2 weeks and 12 weeks d) All of these

21. HAART combines 3 or more ______ medications in a daily regimen, sometimes referred to as
cocktail to cure HIV.

a) Antibiotic b) Antifungal

c) Antiviral d) No medicines are effective against viruses

22. Which form of hepatitis causes a mild infection?

a) Hep. A b) Hep. B

c) Hep. C d) Hep. D

23. Serum hepatitis has a maximum incubation period of ______

a) 26 weeks b) 20 weeks

c) 6 weeks d) No known incubation period

24. _____ is a leading cause of liver transplant.

a) HAV b) HIV

c) HCV d) HBV
25. Medications can cure ____ of the people infected with HCV.

a) Quarter b) Half

c) Three Quarters d) None of these

26. Herpes is usually caused by ______

a) HSV 1 b) HSV 2

c) Both a and b d) None of these

27. Blisters caused by Herpes virus soon open to form painful sores that lasts upto ___ weeks

a) 2 b) 3

c) 4 d) 5

28. Polio virus cannot enter through _______

a) Eyes b) Ear

c) Nose d) Mouth

29. Incubation period of Poliomyelitis is __________

a) 5 to 35 days b) 7 to 14 days

c) Both a and b d) Between 7 weeks and 10 weeks

30. Immunization against Polio is _______ percent effective.

a) Over 90 b) Below 90

c) Almost 90 d) All of these

31. Symptoms of infection in cotton after attack by begomovirus are initially characterized by ________

a) Deep upward cupping of b) Deep downward cupping of youngest leaves

older leaves

c) Formation of enations and swelling d) All of these

on leaves

32. The first symptoms of infection in cotton appear within ____ weeks of inoculation of begomovirus.

a) 2 to 3 b) 3 to 4

c) 2 to 4 d) 1 to 5
33. Chemically, Prions are ______

a) Bits of RNA b) DNA particles

c) Proteins d) Lipids

34. The normal prion proteins are expressed on the stem cells in _______

a) Brain b) Bone marrow

c) Epithelium d) All of these

35. In Scrapie _____ of goat and sheep are affected.

a) Peripheral Nervous System b) Central Nervous System

c) Cardiovascular System d) Both a and b

36. Humans are infected Prions when it is inherited as an apparent hereditary mendelian transmission
where it is an autosomal and _________ trait.

a) Recessive b) Dominant

c) Co dominant d) None of these

37. Viroids are small, circular _____ stranded molecules of infectious ______

a) Single, DNA b) Double, RNA

c) Single, RNA d) Double, DNA

38. The only form of Hepatitis which is not viral is _______

a) Hep. A b) Hep. B

c) Hep. C d) Hep. D

39. The first viroid to be discovered was ______

a) PSTV 1 b) PSTV 2

c) PSTV 3 d) Hep. D

40. HIV cDNA is also called _______

a) Provirus b) Mature Virus

c) Integrase d) HIV is RNA virus and does not contain DNA

41. Genome of influenza virus is surrounded by ______

a) Lipid membrane b) Lipoprotein membrane

c) Glycoprotein d) None of these

42. Some of the genes that control the HIVs ability to infect an individual are ____

a) vpf, vpr, env b) tat, rev, gag

c) gag, pol, env d) vif, vpr, vpu

43. Which of the following virus has RNA of segmented nature?

a) HIV b) Bacteriophage

c) Influenza d) Begomovirus

44. How many spikes spoke out of HIVs viral envelope?

a) 70 b) 120

c) 17 d) 72

45. An HIV particle is ______ the diameter of a human CD4+ white blood cell.

a) 1/70th b) 1/20th

c) 100-150 billionths d) Not yet measured

46. _______ virus can exist in more than one shape.

a) Influenza b) Bacteriophage

c) HIV d) Polio

47. In ____ polio, the virus usually doesnt get past the intestinal tract.

a) Symptomatic b) Abortive

c) Paralytic d) Both a and b

48. Herpes simplex virus type 1 usually causes_______

a) Bumps on Vagina b) Cold sores around mouth

c) Blisters on Penis d) Both a and b

49. When will a bacteriophage virus initiate a lytic cycle?
a) When prophage occasionally exits bacteriophage chromosome

b) When prophage exits bacterial chromosome

c) Both a and b

d) None of these

50. ________ exists as a mushroom shaped box-like head on top of a long stalk.

a) Neuraminidase b ) Sialidase

c) Hemagglutinine d) Both a and b