Generic Dosage, Classification Indication Mechanism of Side Effects Nursing

Name Timing Action Considerations

(Brand Name) and Route

Is used to Doxorubicin is an Pain on the IV Before starting

2 mg/mL, Cytotoxic produce anthracycline site, nausea Doxorubicin
Doxorubicin 25 mL anthracycline regression in antibiotic with and vomiting, treatment,
(Adriamycin, vial, IV antibiotic disseminated antineoplastic low blood make sure
Rubex) neoplastic activity. Doxorubicin, counts hair you tell your
conditions like isolated from the loss, watery doctor about
Price: Anti-cancer / acute bacterium eyes, mouth any other
612.22 anti-neoplastic lymphoblastic Streptomyces sores, medications
1,000 pesos chemotherapy leukemia, acutes peucetius var. darkening of you are taking
drug myeloblastic caesius, is the nail beds, (including
leukemia Wilms hydroxylated darkening of over-the-
Tumor, congener of the skin, counter,
neuroblastoma, daunorubicin. problems with vitamins, or
soft tissue and Doxorubicin fertility, herbal
bone sarcomas, intercalates decrease in the remedies). Do
breast between base pairs hearts not take
carcinoma, in the DNA helix, pumpingactivity aspirin or
ovarian thereby preventing products
carcinoma, DNA replication and containing
transitional cell ultimately inhibiting aspirin unless
bladder protein synthesis. your doctor
carcinoma, Additionally, it permits this.
thyroid inhibits Do not receive
carcinoma, topoisomerase II any kind of
gastric which results in an vaccination
carcinoma, increased cleavable without your
Hodgkins enzyme-DNA linked doctors
disease, complex during DNA approval while
malignant replication and taking
lymphoma and subsequently Doxorubicin.
bronchogenic prevents the ligation Use care to
carcinoma in of the nucleotide keep body
which the small strand after double- fluids from
cell histologic strand breakage. It coming in
type is the most also forms oxygen contact with
responsive free radicals family
compared to resulting in members or
other cell types. cytotoxicity caregivers.
Doxorubicin is secondary to lipid Wash soiled
also indicated for peroxidation of cell
use as a membrane lipids; clothes
component of the formation of immediately
adjuvant therapy oxygen free radicals and use
in women with also contributes to gloves when
evidence of the toxicity of the touching body
axillary lymph anthracycline fluids for at
node antibiotics, namely least 5 days.
involvement the cardiac and Drink two to
following cutaneous vascular three quarts of
resection of effects. fluid every 24
primary breast hours, unless
cancer. you are
instructed
otherwise.
 Generic Dosage, Classification Indication Mechanism of Side Effects Nursing
Name Timing Action Considerations
(Brand Name) and Route

Treatment of Inhibits DNA, RNA, GI: Nausea Should be

10mg/40 Antineoplastic brain tumors, and protein and vomiting. taken with
Lomustine mg/100m Agent, both primary synthesis via Hematologic fluids on an
(Gleostine, g Alkylating (developed in alkylation and & oncologic: empty
CeeNU) Single Agent the brain) and carbamylation of Leukopenia, stomach; no
dose metastatic DNA and RNA bone marrow food or drink
Price: every 6 (spread from depression, for 2 hours
500 3,000 weeks another source). thrombocytope after to
pesos Hodgkin's nia. decrease
disease and CNS: Ataxia, incidence of
non-Hodgkin's disorientation, nausea.
lymphoma. dysarthria, For both men
Also has been lethargy and women:
used in Dermatologic: Do not
treatment of Alopecia conceive a
melanoma, lung Genitourinary: child (get
Azotemia pregnant)
and colon (progressive), while taking
cancer. nephron lomustine.
atrophy, Barrier
nephrotoxicity methods of
Hematologic contraception,
& oncologic: such as
Acute condoms, are
leukemia, recommended
anemia, bone Do not breast
marrow feed while
dysplasia taking this
Hepatic: medication.
Hepatotoxicity, Do not receive
increased any kind of
serum alkaline immunization
phosphatase, or vaccination
increased without your
serum bilirubin, doctor's
increased approval while
serum taking
transaminases lomustine.
Ophthalmic:
Blindness,
optic atrophy,
visual
disturbance
Renal: Renal
failure
Respiratory:
Pulmonary
fibrosis,
pulmonary
infiltrates
Drug Name Dosage, Timing, Classification Indication Mechanism Of Side Effects
Route Action
Drug Name Dosage, Timing Classification Indication Mechanism of Side Effects Nursing
Route Action Considerations

Mitoxantrone INDUCTION Antineoplastics, It is used Anthracenedione; Nausea Administer

(Novantrone) THERAPY: 12 Anthracenedione to treat DNA-reactive Upper slowly into a
mg/m2 IV daily on Multiple prostate agent with cell respiratory freely flowing
20mg days 1 to 3 Sclerosis cancer. cycle nonspecific infection intravenous
inhection: Treatments cytocidal activity Alopecia infusion and
(rupee) SECOND that intercalates Urinary tract never
385.00 or INDUCTION It is used into DNA infection administer IM,
300 pesos THERAPY: 12 to treat a resulting in cross- Amenorrhea SC, or intra-
mg/m2 IV daily on type of links and strand arterially or
Diarrhea
days 1 and 2 leukemia. breaks; inhibits intrathecally
Stomatitis
DNA and RNA
Constipation
CONSOLIDATION synthesis Severe injury
THERAPY: 12 with
mg/m2 given IV permanent
daily on days 1 sequelae can
and 2. The first result from
course is given intrathecal
approximately 6 administration.
weeks after the
final induction Severe local
course and the tissue damage
second is can occur if
generally extravasation
administered 4 occurs during
weeks after the administration
first.
Do not
administer
therapy to
patients with
baseline
neutrophil
counts <1,500
cells/mm.
Perform
peripheral
blood cell
counts to
monitor the
occurrence of
bone marrow
suppression,
primarily
neutropenia,
that may be
severe and
result in
infection