GENERIC NAME INDICATION CONTRAINDICATION SIDE EFFECTS/ DOSAGE NURSING INTERVENTION

BRAND NAME ADVERSE REACTION AVAILABLE FORM

CLASSIFICATION
Clonidine HCl Tab Mild to Diseases affecting Dizziness, headache, paraesthesia, Catapres 150 mcg/1 mL x 5's May be taken with or without
moderate rhythmic & AV sedation, gynaecomastia, confusion state, (P741) food
Catapres hypertension 75-150 conduction system of the delussional perception, depression,
mcg bid. Severe heart; renal failure. hallucination, decreased libido, Catapres tablet Catapres 75 mcg x
Anti-hpn hypertension Impairment of ability to nightmare, sleep disorder, accomodation 100's (P2268)
Increase single dose drive or operate disorder, decreased lacrimation Catapres 150 mcg x 100's (P3456)
to 300 mcg. Could be machinery. Sudden atrioventricular block, bradyarrythmia,
repeated up to tid discontinuance. sinus bradycardia, orthostatic
(900 mcg). Inj 0.2 hypotension. Raynauds's phenomenon,
mcg/kg/min IV nasal dryness, alopecia, pruritus, rash,
infusion, not >150 urticaria, erectile dysfunction, fatigue,
mcg/infusion. malaise, colonic pseudo-obstruction,
constipation, dry mouth, nausea, salivary
gland pain, vomiting.
Isosorbide-5- Prophylactic Shock, constrictive Headache, hypotension w/ dizziness & 60 mg once daily in the morning. May be taken with or without
mononitrate treatment of angina cardiomyopathy, nausea. Tachycardia. Max: 120 mg once daily in the food (May be divided along
pectoris. pericarditis. morning. the score-line. Whole tabs &
Imdur divided halves must be
swallowed whole, do not
Anti-Anginal chew/crush. ).
Drugs May impair the ability to drive
or operate machinery.
Pregnancy & lactation.
Enoxaparin Na Prophylaxis of VTE Conditions w/ a high risk Hemorrhage. Thrombocytopenia. Local Clexane 2000 iu/0.2 mL (20 mg) x History of heparin-induced
disease, in particular of uncontrolled reactions (exceptionally small local 2's (P918.74) thrombocytopenia w/ or w/o
Clexane those which may be hemorrhage including hematoma). Exceptional cases of skin Clexane 4000 iu/0.4 mL (40 mg) x thrombosis. Do not
associated w/ major bleeding disorders. necrosis (discontinue treatment). Rarely, 2's (P1167.82) administer by IM route. Renal
Anticoagulants, orthopedic or Hypersensitivity to cutaneous or systemic allergic reactions. Clexane 6000 iu/0.6 mL (60 mg) x or hepatic insufficiency,
Antiplatelets & general surgery. enoxaparin Na, heparin Increase in liver enzymes, platelet counts. 2's (P1532.2) history of hepatic ulcer,
Fibrinolytics or its derivatives Hypersensitivity cutaneous vasculitis. arterial HTN, diabetic
(Thrombolytics) including other low MW retinopathy, shortly after
heparins. neuro or ophth surgery.
Monitor platelet count
(discontinue if there is
decrease of 30-50% of the
initial value).
Trimetazidine Long-term treatment Not for acute angina Rarely, GI upset (nausea & vomiting). 1 tab morning & evening. Should be taken with food
of coronary attacks, nor as initial (Swallow whole, do not
Vastarel insufficiency; angina treatment for unstable Vastarel MR 35 mg x 60's (P1600) chew/crush.).
pectoris. angina, or MI. Pregnancy.
Anti-Anginal
Drugs
Furosemide Acute pulmonary Hepatic cirrhosis, CHF, Fluid & electrolyte imbalance eg Adult 20-50 mg IM/IV. If response Hepatic cirrhosis, CHF,
edema, CHF, edema borderline renal failure. hyponatremia & ECF depletion, is inadequate after 1-2 hr, increase borderline renal failure.
Fremid of nephrotic Prostatic hyperplasia or hypochloremic alkalosis, hypokalemia. dose to 80 mg by slow IV. May be Prostatic hyperplasia or other
syndrome, severe other condition Ototoxicity manifested as tinnitus, given as 1-2 doses daily or condition associated w/
Diuretics HTN, ascites & associated w/ deafness & vertigo. Hypersensitivity intermittently. Childn 0.5-1.5 impairment of micturition.
edema due to liver impairment of reactions eg skin rashes, drug fever, mg/kg/day, max of 20 mg/day. Acute gouty arthritis & DM.
cirrhosis, acute renal micturition. Acute gouty interstitial nephritis & photosensitivity. Infant 1 mg/kg/day. Administration
failure. arthritis & DM. Hyperuricemia, hyperglycemia & rate should not exceed 4 mg/min.
dyslipidemia.
Simvastatin Used as an adjunct to Active liver disease or Abdominal pain, constipation, flatulence. CHD, Hyperlipidemia Initially 20 May be taken with or without
diet to reduce unexplained persistent Asthenia, headache. Nausea, diarrhea, mg/day as a single dose in the food (Avoid excessive
Stavid elevated total elevations of serum rash, dyspepsia, pruritus, alopecia, evening. If needed, adjust dose at consumption (> 1 L/day) of
cholesterol, LDL- transaminases, dizziness, muscle cramps, myalgia, intervals not <4 wk. Max: 80 grapefruit juice.).
Dyslipidaemic cholesterol, porphyria, pregnancy & pancreatitis, paraesthesia, peripheral mg/day as a single dose in the
Agents apolipoprotein B, lactation, women of neuropathy, vomiting & anemia. Increase evening. Homozygous familial Active liver disease or
triglycerides in childbearing potential of serum transaminases. hypercholesterolemia 40 mg/day unexplained persistent
patients w/ unless adequately in the evening or 80 mg/day in elevations of serum
hypercholesterolemi protected by non divided doses of 20 mg, 20 mg & transaminases, porphyria,
a or combine (mixed) hormonal methods. evening dose of 40 mg. Patients pregnancy & lactation,
hyperlipidemia when taking cyclosporin, fibrates or women of childbearing
response to diet & niacin Max: 10 mg/day. Severe potential unless adequately
other non- renal insufficiency Dose >10 protected by non hormonal
pharmacological mg/day should be cautiously methods.
measure is implemented.
inadequate.
Increases HDL- Stavid 20 mg x 100's (P1600)
cholesterol level.
Omeprazole Duodenal ulcer Presence of significant Headache, diarrhea, constipation, Duodenal ulcer 20 mg once daily May be taken with or without
Gastric ulcer & reflux unintentional wt loss, abdominal pain, nausea, vomiting, for 2-4 wk. Prevention of relapse of food (For patients w/
Losec esophagitis recurrent vomiting, flatulence. duodenal ulcer 10 mg once daily. swallowing difficulties, the
peptic ulcer dysphagia, hematemesis Max: 20-40 mg once daily. Gastric cap may be opened & the
Antacids, Dyspepsia or melena. Exclude ulcer & reflux esophagitis 20 mg contents swallowed or
Antireflux GERD malignancy if gastric once daily for 4-8 wk. Poorly suspended in a slightly acidic
Agents & Zollinger-Ellison ulcer is suspected. responsive gastric ulcer 40 mg fluid eg fruit juice or in non-
Antiulcerants syndrome once daily for 8 wk. Severe reflux carbonated water. The susp
esophagitis 40 mg once daily for 8 should be drunk within 30
wk. Long-term management: 10 mins. Alternatively, these
mg once daily, increased to 20-40 patients can suck the cap &
mg once daily. swallow the contents. The
contents of the cap should
not be chewed/crushed.).
Lactulose Adult: PO Galactosaemia, intestinal Diarrhoea (dose-related), nausea, Hepatic encephalopathy 60-100 g May be taken with or without
Constipation Initial: obstruction. Patients on vomiting, hypokalaemia, bloating and (90-150 mL)/day in 3 divided food. (May be taken w/ meals
Laxatives, 10-20 g (15-30 low galactose diet. abdominal cramps. doses; adjust accordingly. Rectal to reduce GI discomfort.)
Purgatives mL)/day. Max: 45 mL Potentially Fatal: Dehydration and Hepatic encephalopathy Mix 200 g Monitor electrolyte
(or 40 g of the hypernatraemia on aggressive treatment. (300 mL w/ 700 mL water or 0.9% imbalance. Lactose
reconstituted oral NaCl as a retention enema. Retain intolerance; diabetics.
formulation)/day. enema for 30-60 mins; repeat 4-6
[Continued on hrly until oral medication can be
 DOSAGE column] administered.
Allopurinol Management of signs Asymptomatic Hypersensitivity, skin, renal, CV, Initially 100 mg/day. Usual Should be taken with food
& symptoms of hyperuricemia. Childn. endocrine & metabolic reactions; maintenance dose: Mild cases100-
Purinase primary & secondary hematologic & hepatic effects; GI, 200 mg. Moderately severe cases Discontinue immediately at
gout eg acute nervous system & resp disturbances; 300-600 mg. Severe cases 700-900 1st appearance of rash or any
Hyperuricemia attacks, tophi, joint Stevens-Johnson syndrome. mg. Doses over 300 mg should be allergic reaction. Patients on
& Gout destruction, uric acid given in divided doses. diuretics or ACE inhibitors.
Preparations lithiasis &/or For hyperuricemia associated
nephropathy. w/ cancer therapy, allopurinol
Leukemia, treatment should be given
lymphoma, solid prior to cancer therapy.
tumor malignancies Hepatic or renal dysfunction
in patients (reduce dose). Pregnancy &
undergoing lactation.
chemotherapy.
Reccurent mixed Ca
oxalate renal calculi
w/ daily acid
secretion exceeds
750-800 mg/day. 2,8-
DHA renal stones.
Enzyme disorders
that lead to the
overproduction of
urate.
GENERIC NAME INDICATION CONTRAINDICATION SIDE EFFECTS/ DOSAGE NURSING INTERVENTION
BRAND NAME ADVERSE REACTION AVAILABLE FORM
CLASSIFICATION
Hydrocortisone Primary & secondary Septic shock; systemic GIT & musculoskeletal effects; fluid & 100-500 mg IV/IM, may be May mask symptoms of
Na succinate adrenocortical fungal infections. electrolyte imbalance; impaired wound repeated every 2, 4 or 6 hr. Childn infection. Avoid
insufficiency; healing, skin atrophy, increased sensitivity 25 mg daily. Adjust dose according immunizations & restrict salt
Pharmacort endocrine, to skin lesions, striae, inreased sweating, to severity of condition & patient's & K intake during therapy.
hematologic, telangiectasis, acne. Endocrine & reaction to treatment. Patients w/ history of
Corticosteroid rheumatic & collagen metabolic disorders; CNS & ophth effects. decompensation, HTN, peptic
Hormones disorders; severe Opportunistic infections, anaphylactoid Pharmacort 250 mg x 1's (P336) ulcer, glaucoma, previous
shock, bilateral reaction. steroid myopathy, epilepsy,
adrenalectomy, DM, osteoporosis, chronic
acute psychotic reactions & TB.
hypersensitivity Nonspecific colitis ulcerosa,
reactions, severe diverticulitis, fresh intestinal
lupus erythematosus anastomosis, renal
in relapse; other insufficiency, hypertonicity &
conditions requiring myasthenia gravis. Ocular
immediate metabolic herpes simplex. Avoid
& anti-inflammatory prolonged use. Pregnancy &
actions of lactation. Childn.
hydrocortisone.
Ranitidine HCl Treatment of GI malignancy. Severe Reversible hepatitis, hypersensitivity Tab 150 mg in the morning & in GI malignancy. Severe renal
duodenal ulcer, renal impairment. reactions, headache, dizziness. Rarely, the evening. Duodenal & gastric impairment. Pregnancy &
Ulcin benign gastric ulcer, Pregnancy & lactation. agranulocytosis, reversible leucopenia & ulcers 150 mg bid or 300 mg at lactation.
post-op ulcer, reflux thrombocytopenia. Diarrhea, muscle pain bedtime for 4-8 wk. Esophagitis
Antacids, esophagitis, & skin rash. 150 mg bid for 6 wk. Maintenance:
Antireflux Zollinger-Ellison 150 mg in the evening. Zollinger-
Agents & syndrome & the Ellison syndrome 150 mg tid & may
Antiulcerants following conditions be increased up to 600-900 mg. Inj
where reduction of 50 mg by slow IV inj over 1 min, or
gastric secretion & as an intermittent IV infusion at a
acid output is rate of 25 mg/hr for 2 hr, or as an
desirable: IM inj of 50 mg (2 mL). May be
Prophylaxis of GI repeated at 6-8 hrly. Prophylaxis of
hemorrhage from hemorrhage from stress ulceration
stress ulceration in or recurrent hemorrhage from
seriously ill patients, peptic ulceration Parenteral
prophylaxis of administration may be continued
recurrent until oral feeding commences. Risk
hemorrhage in of acid aspiration syndrome 50 mg
patients w/ bleeding by IM or slow IV inj (over 1 min)
peptic ulcer & before 45-60 min before induction of
general anesth in general anesth.
patients at risk of
acid aspiration, esp Ulcin 25 mg/1 mL x 10's
obstetric patients (P1176/box)
 during labor
(Mendelson's
syndrome).
Erythromycin Upper & lower resp Impaired hepatic GI disturbances eg abdominal cramping & Adult 250 mg 6 hrly, may be Should be taken on an empty
estolate tract, skin & soft function. May interfere discomfort, nausea, vomiting. Hearing increased up to ≥4 g/day. Childn stomach (Best taken on an
tissue infections of w/ AST (SGOT) & urinary loss &/or tinnitus. Urticaria, skin rashes 30-50 mg/kg body wt in divided empty stomach 1 hr before or
Ilosone mild to moderate catecholamine including anaphylaxis. Infantile doses. Severe infections: Dosage 2 hr after meals. May be
severity. Primary determination. Monitor hypertrophic pyloric stenosis. may be doubled. taken w/ meals to reduce GI
Macrolides syphilis in penicillin- creatinine kinase & discomfort.).
allergic patients. serum transaminase Cholestatic hepatitis,
Uncomplicated levels. jaundice. Preexisting liver
urethral endocervical Pseudomembranous disease.
& rectal infections colitis. Infants. Pregnancy
due to C. & lactation.
trachomatis.
Prophylaxis for
pertussis. Diphtheria
& erythrasma.
Conjunctivitis in
newborn, pneumonia
in infants &
urogenital infections
during pregnancy.