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FLIBAN 100 MG
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Buy Fliban 100mg, the rst and only FDA-approved treatment for acquired, generalized Hypoac ve S**ual Desire
Disorder (HSDD) in premenopausal women. Fliban is a non-hormonal prescrip on pill used to treat Hypoac ve (low)
S**ual Desire Disorder (HSDD) in women who have not gone through menopause, who have not had
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What is Fliban?
The rst and only FDA-approved treatment for acquired, generalized Hypoac ve S**ual Desire Disorder
(HSDD) in premenopausal women. dened by the FDA as characterized by low s**ual desire that causes
marked distress or interpersonal diculty and is not due to a co-exis ng medical or psychiatric condi on,
problems within the rela onship, or the eects of a medica on or other drug substance. (I already have
ques ons: does breas eeding count as a co-exis ng medical condi on? Wait, is it safe while breas eeding?
Sigh. Nevermind.)
Fliban is a non-hormonal prescrip on pill used to treat Hypoac ve (low) S**ual Desire Disorder (HSDD) in
women who have not gone through menopause, who have not had problems with low s**ual desire in the
past, and who have low s**ual desire no ma er the type of s**ual ac vity, the situa on, or the s**ual
partner. Women with HSDD have low s**ual desire that is troubling to them. Their low s**ual desire
is not due to:
a medical or mental health problem
problems in the rela onship
medicine or other drug use
Fliban is not for use for the treatment of HSDD in women who have gone through menopause or in men.
Fliban is not for use to improve s**ual performance. Fliban is not for use in children.
Take Fliban only at bed me. Taking Fliban at a me other than bed me can increase your risk of low blood
pressure, fain ng (loss of consciousness), accidental injury, and sleepiness.
Female s**ual complaints are so, so common, and some of the best data we have say that somewhere
between 40% and 50% of women across the spectrum have some kind of complaint of s**ual dysfunc on. Its
hugely common in one form or another, and there has not been much success in drug development for that.
At the hearing for the advisory commi ee, the Even the Score group brought in 20 women to provide
tes mony about the degree of suering and how their s**ual dysfunc on was really aec ng their lives, their
rela onships and their sense of well-being.
How serious is female s**ual dysfunction and the concerns that women have regarding th
libido?
Its really prevalent across popula ons. I see mostly peri-menopausal and post-menopausal women but also
women in their 20s and 30s as well. [Note: The best study, she said, is a 1999 study in JAMA that found 43% of
women and 31% of men complained of some form of s**ual dysfunc on.] It is very distressful for women, and
the FDA has approved the drug specically for a lack of s**ual desire that causes distress to the woman or in
her rela onship. I have a lot of pa ents who never have s**, and theyre okay with that. The only me its a
problem is if its a problem for the woman or her partner. By deni on, its a condi on thats causing distress.
What exactly does flibanserin (Fliban) do? How does it act on the body?
Thats whats really interes ng about this. People are hyping this as the female Sildenal, but its really
dierent from Sildenal in a couple of important ways. Number one, Sildenal works almost 100% of me for
men. But only 1 in 10 women is going to benet from ibanserin, so its much less eec ve than Sildenal.
Number two, Sildenal works by increasing blood ow to the pe**is, whereas ibanserin works on
neurotransmi ers in the brain, almost like an depressants. [Flibanserin is actually a failed
an depressantwhose mechanism on mice was to act on serotonin in a way dierent than other
an depressants and to increase dopamine.]
Number three, with Sildenal, men just take it when they want to have s**. Women have to take ibanserin
every day, and it takes about four weeks to begin to see an eect. Peak eects arent seen un l eight weeks.
How many women want to take a drug every day that aects their brain to improve their libido?
What are the possible side effects of flibanserin (Fliban)? Can you discuss the intera
with alcohol in particular?
It has pre y signicant side eects. The big ones are nausea, dizziness and fain ng. [According to the FDA, the
most common adverse reac ons associated with the use of Fliban are dizziness, sleepiness, nausea, fa gue,
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insomnia and dry mouth.] Its designed to be taken at night. We have to be very careful not to give it to
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women who have condi ons that could make a problem from the drug worse. Say a woman already has a
blood pressure condi on. Then you add this drug, and shes fain ng at work or while driving.
How effective is it really? How well does it work, and how many women could benefit?
Thats the other thing in the women we think might be candidates for this drug, does it work? In the trials,
they found that women at baseline were having 2.7 s**ually sa sfying events per month. S**ually sa sfying
events were dened as intercourse, manual s**, oral s**, or masturba on, with or without orgasm. Women
taking the placebo went to 3.7 events per month, and women taking ibanserin went to 4.5 per month. [So,
women are ge ng not quite one whole addi onal s**ually sa sfying event poten ally without orgasm
than on placebo.]
These were well designed trials, and the eect seemed to be real, but its small, and it only occurred in about
10% of women. One could argue that what we have here is a minor aphrodisiac with scary side eects. How
many women are going to be eligible for the drug and how eec ve are they going to feel that it is?
We dont have any long-term data. Any me a new drug is brought to market, its on the basis of short-term
studies, and it remains to be seen how its going to be tolerated over me. Again, this drug is designed to be
taken every day like an an depressant and presumably a person would be maintained on it, so thats an
unanswered ques on right now.
I spend a fair amount of me talking to my pa ents about whats normal. The tradi onal model of s**ual
response (research by Masters and Johnson) is that s**ual ac vity starts with desire, goes up through arousal,
then plateaus a li le bit, there is an orgasm (or several orgasms), and then theres resolu on. This is an up and
down model. That actually has turned out not to be the case for most women.
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